Mouse anti-Human BST1 polyclonal antibody (DPAB-DC2996) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol- anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Immunogen BST1 (AAH12095.1, 1 a.a. ~ 318 a.a) full-length recombinant with GST tag. The sequence is MAAQGCAASRLLQLLLQLLLLLLLLAAGGARARWRGEGTSAHLRDIFLGRCAEYRALLSPEQRN KNCTAIWEAFKVALDKDPCSVLPSDYDLFINLSRHSIPRDKSLFWENSHLLVNSFADNTRRFMPL SDVLYGRVADFLSWCRQKNDSGLDYQSCPTSEDCENNPVDSFWKRASIQYSKDSSGVIHVML NGSEPTGAYPIKGFFADYEIPNLQKEKITRIEIWVMHEIGGPNVESCGEGSMKVLEKRLKDMGFQ YSCINDYRPVKLLQCVDHSTHPDCALKSAAAATQRKAPSLYTEQRAGLIIPLFLVLASRTQL

Source/Host Mouse

Species Reactivity Human

Conjugate Unconjugated

Applications WB (Recombinant protein), ELISA,

Size 50 μl

Buffer 50 % glycerol

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name BST1 bone marrow stromal cell antigen 1 [ Homo sapiens (human) ]

Official Symbol BST1

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms BST1; bone marrow stromal cell antigen 1; CD157; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; BST-1; cADPr hydrolase 2; NAD(+) nucleosidase; ADP-ribosyl cyclase 2; bone marrow stromal antigen 1; cyclic ADP-ribose hydrolase 2;

Entrez Gene ID 683

Protein Refseq NP_004325

UniProt ID Q10588

Chromosome Location 4p15

Pathway Nicotinate and nicotinamide ; Pancreatic secretion; Salivary secretion;

Function NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; transferase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved