In This Issue… WINTER 2014–2015 3 Focus onon PublicPublic Affairs Affairs: 6 nMembers Government in the News Re-opens n afterFour 16-DayElected Shutdownto IOM: n AAIRafi Recognizes Ahmed 2013 PublicArturo ServiceCasadevall Award HonoreesJames Crowe, Jr. John O’Shea 6 AAI Council Welcomes New nCouncillor Jane Salmon JoAnne Flynn 7 JoAnnen Geor geL. Flynn’sTsokos 2013 AAI Candidate’s Statement 13 In Memoriam 8 Members in the News n Herman Eisen n y RandBrutkiewicz n Stephen Kaattari n Ruslan Medzhitov 17 The Journal of : n Joshua Obar Dos and Don’ts of Image 13 ManipulationIn Memoriam: Yacov Ron, Ph.D. 18 Outreach Program Update 14 AAI Looks Back 20 Grant Review for 22 myIDP Prepares Trainees Immunologiststo Transition to Program the Update“Final Frontier” 2522 Re-Cap:High School Summer Teachers 2013 Program AAI ParticipantsIntroductory Present Immunology at NABT 24 GrantCourse & Award Deadlines 26 Re-Cap: Summer 2013 AAI 26 AAI Welcomes New Members Advanced Immunology 30 MeetingsCourse Calendar 28 AAI Members and Staff Participate in 15th ICI 30 AAI Announces Tiered Awards for the 2014 Modest Increase Trainee Abstract Award Program for NIH Offers Small 32 Grant & Award Deadlines Bright Spot in Just- 34 Meetings & Events Calendar Passed Funding Law See Story on page 4 Important Dates for Two AAI Awards Programs AAI Programs to Benefit Your Lab’s Current or Future Research

AAI Careers in AAI Travel for Techniques Immunology Fellowship Award Program

KEY DATES APPLICATIONS OPEN APPLICATIONS CLOSE AWARDS CYCLE APPLICATIONS OPEN APPLICATIONS CLOSE JANUARY 15 MARCH 16 WINTER DECEMBER 15 FEBRUARY 15 SPRING APRIL 15 JUNE 15 These fellowships provide AAI member PIs with one year of FALL AUGUST 15 OCTOBER 15 salary support for a graduate student or postdoctoral fellow in their labs. Member PIs in good standing with less than The Travel for Techniques Award is given to member PIs, $250,000 (excluding PI’s salary) in annual direct costs are reimbursing up to $1,500 in expenses for travel to learn eligible to apply. a new technique. Member PIs in good standing with less Selection is based on the potential of the trainee, merit of the than $250,000 (excluding PI’s salary) in annual direct costs project, quality of the training environment, and financial need. are eligible to apply. Direct inquiries to [email protected]. Direct inquiries to [email protected].

These two exciting awards programs were launched by the American Association of Immunologists in 2014, adding significantly to its already robust support for scientists through fellowships, career awards, and travel grants. For more information, visit www.aai.org/awards.

AAI1413_NEW_AWARDS_AD_Revised.indd 1 11/21/14 9:54 AM Focus on Public Affairs Republicans Take Control of the Senate, Expand Majority in the House Congress to Welcome at Least 68 New Members As a result of the November elections, The American Association the 114th Congress, which is set to begin of Immunologists on January 6, 2015, will include at least 9650 Rockville Pike 68 new faces: 61 in the House and 13 Bethesda, MD 20814-3994 in the Senate (with seven new senators Tel: 301-634-7178 having previously served in the House Fax: 301-634-7887 of Representatives). For the first time E-mail: [email protected] in eight years, the Republican Party will www.aai.org have a majority in both chambers of Congress. Senator Mitch McConnell (R- Member Services KY), the current Senate Minority Leader, Tel: 301-634-7195 will take over as Senate Majority Leader, E-mail: [email protected] while Rep. John Boehner will retain his position as Speaker of the House of The Journal Representatives. of Immunology Tel: 301-634-7197 Republicans gained nine seats in E-mail: [email protected] the Senate, giving them a total of 54 seats. Democrats have 44 seats but can Important Dates for Two AAI Awards Programs www.jimmunol.org generally count on the support of two independent senators, both of whom will caucus with the Democratic Party.

AAI Programs to Benefit Your Lab’s Current or Future Research Council The Republican Party also expanded its majority in the House of Representatives, gaining 13 seats for an advantage of 247 to 188. President Linda A. Sherman, Ph.D. With majorities in both chambers, the Republican Party will have a greater ability to control the agenda. But legislating will continue to require Vice President compromise, because most controversial bills in the Senate require 60 votes to AAI Careers in AAI Travel for Techniques Dan R. Littman, M.D., Ph.D. pass and because bills that are passed by both chambers may be vetoed by the Past President president. Overriding a presidential veto requires a two-thirds majority vote in Immunology Fellowship Award Program Marc K. Jenkins, Ph.D. both the House and the Senate. Secretary-Treasurer NIH and the broader scientific community will lose a number of long-term KEY DATES APPLICATIONS OPEN APPLICATIONS CLOSE AWARDS CYCLE APPLICATIONS OPEN APPLICATIONS CLOSE Mitchell Kronenberg, Ph.D. champions when the 114th Congress begins. Longtime NIH advocate Senator JANUARY 15 MARCH 16 WINTER DECEMBER 15 FEBRUARY 15 Councillors Tom Harkin (D-IA) is retiring after five terms in the House of Representatives SPRING APRIL 15 JUNE 15 Arlene H. Sharpe, M.D., Ph.D. and five terms in the Senate—a total of 40 years of public service. Harkin has These fellowships provide AAI member PIs with one year of FALL AUGUST 15 OCTOBER 15 Wayne M. Yokoyama, M.D. served as either the chair or ranking member of the Senate Labor, Health, salary support for a graduate student or postdoctoral fellow JoAnne L. Flynn, Ph.D. and Human Services, Education, and Related Agencies Appropriations Subcommittee, which funds NIH, since 1989. He was also a co-recipient of the in their labs. Member PIs in good standing with less than The Travel for Techniques Award is given to member PIs, Jeremy M. Boss, Ph.D. AAI Public Service Award in 2001. $250,000 (excluding PI’s salary) in annual direct costs are reimbursing up to $1,500 in expenses for travel to learn Ex Officio Councillors Pamela J. Fink, Ph.D. The House of Representatives will also lose a leading science advocate to eligible to apply. a new technique. Member PIs in good standing with less Wendy L. Havran, Ph.D. retirement—eight-term Congressman and physicist Rush Holt (D-NJ, 12th). Selection is based on the potential of the trainee, merit of the than $250,000 (excluding PI’s salary) in annual direct costs M. Michele Hogan, Ph.D. Among other things, Holt was a co-chair of the Congressional Biomedical Research Caucus. Although his congressional service will be coming to an are eligible to apply. Eugene M. Oltz, Ph.D. project, quality of the training environment, and financial need. end, his commitment to science remains strong. In February, Holt will join Executive Director Direct inquiries to [email protected]. Direct inquiries to [email protected]. the American Association for the Advancement of Science as chief executive M. Michele Hogan, Ph.D. officer and executive publisher of Science and its family of journals. www.aai.org/ About/Departments-Staff These two exciting awards programs were launched by the American Association of Immunologists in 2014, adding significantly to its already robust support for scientists through fellowships, career awards, and travel grants. For more information, visit www.aai.org/awards. www.aai.org AAI Newsletter 3

AAI1413_NEW_AWARDS_AD_Revised.indd 1 11/21/14 9:54 AM Focus on Public Affairs ™ NIH Receives Small Increase for Current Year IMMUNOLOGY 2015 THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS New Law includes $5.4 Billion appropriation of $65 million, an increase of $25 million MAY 8–12, 2015 I AAI ANNUAL MEETING I NEW ORLEANS, LA to Combat Ebola from the FY 2014. The new law also includes $12.6 million to support the Gabriella Miller Kids First Research Act, Following significant debate, arcane procedural a bill sponsored by former House Majority Leader Eric maneuvers, and the passage of two very short term Cantor to increase NIH funding for pediatric research. funding extensions, Congress approved a “CROmnibus” In addition, the National Institute on Aging received a Call for 2015 Award Applications appropriations bill on December 13. The CROmnibus, $25 million increase, of which Congress expects that a Deadline: January 12, 2015 which President Obama signed into law on December “significant portion” should be directed to research on Applications are invited for the following AAI Travel Awards and Grants, which annually foster the promise and professional 16, funds the Department of Homeland Security under Alzheimer’s disease. a Continuing Resolution (“CR”) at its previous year’s development of investigators of all career stages, including underrepresented minority scientists and trainees. level through February 27, 2015, while funding NIH and The CROmnibus is accompanied by a report which Lefrançois-BioLegend Memorial Award Lustgarten-eBioscience Memorial Award all other federal agencies and programs (through an provides detailed guidance to federal departments and agencies, including spending instructions and other Established to honor the memory of AAI member Dr. Leo Lefrançois, Established to honor the memory of AAI member Dr. Joseph Lustgarten, omnibus appropriations bill) at their new levels through this award is intended to advance the career of a trainee who this award is intended to advance the career of a mid-career scientist who September 30, 2015. directives. The new law includes 17 pages of report attends the AAI annual meeting and presents an outstanding attends the AAI annual meeting and presents an outstanding abstract language that specifically pertain to NIH. Among other abstract specifically in the area of mucosal immunology. The award specifically in the area of immune regulation. The award recipient will The new law includes $30.05 billion for NIH in fiscal things, NIH is asked to: recipient will receive a $1,000 cash award and a certificate during receive up to $1,250 travel reimbursement and a certificate during an year (FY) 2015, an increase of $150 million (0.5 percent) • create an Administrative Burden Workgroup within an awards presentation program at the AAI annual meeting. awards presentation program at the AAI annual meeting. This award is gener- over the FY 2014 level. In addition, NIH received $238 60 days of enactment of the bill with the objective of This award is generously supported through a grant from BioLegend ously supported through a grant from eBioscience, an Affymetrix Company. and donations from friends and colleagues of Dr. Lefrançois. million in emergency funding to support Ebola research reducing current onerous requirements AAI Underrepresented Scientist Travel Awards and vaccine development, the full amount requested by • develop a plan to reduce the average age at which AAI Trainee Poster Awards These awards provide travel support to eligible AAI members to attend the President Obama for NIH. In total, Congress provided investigators receive their first R01 These awards provide up to $300 travel reimbursement to AAI trainee AAI annual meeting. Two types of awards are available (trainee, junior faculty), $5.4 billion of the $6.18 billion requested for all agencies • provide a report to the House and Senate members (students and postdoctoral fellows) whose first-author providing support of up to $1,850 for registration and meeting-related travel by the president to combat the Ebola epidemic. abstracts submitted to the AAI annual meeting are selected for poster expenses. This award is generously supported through the FASEB Minority Appropriations Committees on how it plans to proceed sessions only and found to be exceptional by the AAI Abstract Access to Research Careers (MARC) program and a grant from the National Part of the $150 million in new NIH money is with the National Children’s Study. (The fate of this Programming Chairs. Selection is based on the originality and Institute of General Medical Sciences (NIGMS), NIH. earmarked for specific programs. The President’s directive is somewhat at issue, however, given that NIH significance of the research being presented. Director Francis Collins has announced that NIH has AAI Trainee Abstract Awards Brain Research through Advancing Innovative Pfizer-Showell Travel Award Neurotechnologies (BRAIN) Initiative received a total cancelled the study.) These awards provide up to $500–750 travel reimbursement to AAI trainee This award recognizes the professional promise of an early career members (students and postdoctoral fellows) whose first-author abstracts investigator (assistant professor or equivalent) by assisting the award submitted to the AAI annual meeting are selected for presentation in ™ recipient with travel to the AAI annual meeting. Selection is based on block symposia. career progress and submission of an outstanding abstract selected ™ for oral presentation in a block symposium at the meeting. The award AAI Undergraduate Faculty Travel Grants IMMUNOLOGY 2015 recipient will be recognized and presented with a certificate at an These grants assist undergraduate faculty in attending the AAI annual meeting. THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS awards presentation program at the AAI annual meeting. Support Each grant will also support travel costs for an undergraduate student of the IMMUNOLOGY 2015 of up to $1,500 will be provided for meeting registration and travel. recipient’s selection. A grant of up to $1,250 is awarded to the undergraduate MAY 8-12, 2015 | AAI ANNUAL MEETING | NEW ORLEANS, LA THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS This award is supported through an endowment from Henry J. Showell faculty member, and a grant of up to $1,000 is awarded to the selected under- MAY 8-12, 2015 | AAI ANNUAL MEETING | NEW ORLEANS, LA and Pfizer, Inc. graduate student (registration for an undergraduate student is complimentary). AAI-Thermo Fisher Trainee Achievement Awards AAI Laboratory Travel Grants MARK YOUR CALENDAR! These awards recognize up to six promising trainees in the field of Now open to both mid-career and senior investigators! immunology. Selection is based on career promise and presentation These grants assist mid-career and senior investigators in attending the AAI of an outstanding first-author abstract selected for oral presentation MARK YOUR CALENDAR! annual meeting. Applicants must hold an appointment of associate professor, in a block symposium. Awardees will receive a $1,000 cash prize full professor, or equivalent; have limited research funding; and be a first and reimbursement for meeting expenses. This award is generously or last author on one or more abstracts submitted to the annual meeting. ABSTRACTS HOUSING supported through a grant from Thermo Fisher Scientific. Each grant will provide two travel awards of up to $1,250 each: one to the Regular Abstract Submissions Now OPEN! Housing Reservations Now OPEN! ABSTRACTS HOUSING AAI Early Career Faculty Travel Grants PI or laboratory director and another to a member of his or her lab, chosen Regular Abstract Submissions Close January 12, 2015 Discounted Hotel Rate Closes April 9, 2015 by the PI or laboratory director. Recipients will be reimbursed for registration www.IMMUNOLOGY2015.org/abstractRegular Abstract Submissions Now OPEN! www.IMMUNOLOGY2015.org/housingHousing Reservations Now OPEN! These grants assist young investigators (assistant professor or and travel expenses. Regular Abstract Submissions Close January 12, 2015 Discounted Hotel Rate Closes April 9, 2015 equivalent) in attending the AAI annual meeting. Recipients will be reimbursed up to $1,250 for registration and travel expenses. www.IMMUNOLOGY2015.org/abstract www.IMMUNOLOGY2015.org/housing For complete AAI Travel Award and Grant Chambers-eBioscience Memorial Award application details, visit www.AAI.org/Awards. AWARDS REGISTRATION Established to honor the memory of AAI member Dr. Cynthia Chambers, this award is intended to advance the career of an early The 2015 AAI Awards will be presented in conjunction with Travel Award, Grant Application Submissions Now OPEN! Registration Opens December 10, 2014 AWARDS REGISTRATION career scientist who attends the AAI annual meeting and presents ™ Travel Award, Grant Application Deadline is January 12, 2015 Early Registration Discount Ends March 23, 2015 an outstanding abstract specifically in the area of cancer biology. IMMUNOLOGY 2015 Travel Award, Grant Application Submissions Now OPEN! Registration Opens December 10, 2014 www.IMMUNOLOGY2015.org/awards www.IMMUNOLOGY2015.org/registration The award recipient will receive a $1,000 cash award and a certificate May 8–12, 2015 • New Orleans, Louisiana Travel Award, Grant Application Deadline is January 12, 2015 Early Registration Discount Ends March 23, 2015 during an awards presentation program at the AAI annual meeting. www.IMMUNOLOGY2015.org/awards www.IMMUNOLOGY2015.org/registration This award is generously supported through a grant from eBioscience, Questions? Contact AAI at 301-634-7178 an Affymetrix Company. or [email protected] 4 AAI Newsletter Winter 2014-2015

Imm2015_CFAwardApp.indd 1 10/1/14 12:03 PM IMMUNOLOGY 2015™ THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS MAY 8–12, 2015 I AAI ANNUAL MEETING I NEW ORLEANS, LA Call for 2015 Award Applications Deadline: January 12, 2015 Applications are invited for the following AAI Travel Awards and Grants, which annually foster the promise and professional development of investigators of all career stages, including underrepresented minority scientists and trainees.

Lefrançois-BioLegend Memorial Award Lustgarten-eBioscience Memorial Award Established to honor the memory of AAI member Dr. Leo Lefrançois, Established to honor the memory of AAI member Dr. Joseph Lustgarten, this award is intended to advance the career of a trainee who this award is intended to advance the career of a mid-career scientist who attends the AAI annual meeting and presents an outstanding attends the AAI annual meeting and presents an outstanding abstract abstract specifically in the area of mucosal immunology. The award specifically in the area of immune regulation. The award recipient will recipient will receive a $1,000 cash award and a certificate during receive up to $1,250 travel reimbursement and a certificate during an an awards presentation program at the AAI annual meeting. awards presentation program at the AAI annual meeting. This award is gener- This award is generously supported through a grant from BioLegend ously supported through a grant from eBioscience, an Affymetrix Company. and donations from friends and colleagues of Dr. Lefrançois. AAI Underrepresented Scientist Travel Awards AAI Trainee Poster Awards These awards provide travel support to eligible AAI members to attend the These awards provide up to $300 travel reimbursement to AAI trainee AAI annual meeting. Two types of awards are available (trainee, junior faculty), members (students and postdoctoral fellows) whose first-author providing support of up to $1,850 for registration and meeting-related travel abstracts submitted to the AAI annual meeting are selected for poster expenses. This award is generously supported through the FASEB Minority sessions only and found to be exceptional by the AAI Abstract Access to Research Careers (MARC) program and a grant from the National Programming Chairs. Selection is based on the originality and Institute of General Medical Sciences (NIGMS), NIH. significance of the research being presented. AAI Trainee Abstract Awards Pfizer-Showell Travel Award These awards provide up to $500–750 travel reimbursement to AAI trainee This award recognizes the professional promise of an early career members (students and postdoctoral fellows) whose first-author abstracts investigator (assistant professor or equivalent) by assisting the award submitted to the AAI annual meeting are selected for presentation in recipient with travel to the AAI annual meeting. Selection is based on block symposia. career progress and submission of an outstanding abstract selected for oral presentation in a block symposium at the meeting. The award AAI Undergraduate Faculty Travel Grants recipient will be recognized and presented with a certificate at an These grants assist undergraduate faculty in attending the AAI annual meeting. awards presentation program at the AAI annual meeting. Support Each grant will also support travel costs for an undergraduate student of the of up to $1,500 will be provided for meeting registration and travel. recipient’s selection. A grant of up to $1,250 is awarded to the undergraduate This award is supported through an endowment from Henry J. Showell faculty member, and a grant of up to $1,000 is awarded to the selected under- and Pfizer, Inc. graduate student (registration for an undergraduate student is complimentary). AAI-Thermo Fisher Trainee Achievement Awards AAI Laboratory Travel Grants These awards recognize up to six promising trainees in the field of Now open to both mid-career and senior investigators! immunology. Selection is based on career promise and presentation These grants assist mid-career and senior investigators in attending the AAI of an outstanding first-author abstract selected for oral presentation annual meeting. Applicants must hold an appointment of associate professor, in a block symposium. Awardees will receive a $1,000 cash prize full professor, or equivalent; have limited research funding; and be a first and reimbursement for meeting expenses. This award is generously or last author on one or more abstracts submitted to the annual meeting. supported through a grant from Thermo Fisher Scientific. Each grant will provide two travel awards of up to $1,250 each: one to the AAI Early Career Faculty Travel Grants PI or laboratory director and another to a member of his or her lab, chosen by the PI or laboratory director. Recipients will be reimbursed for registration These grants assist young investigators (assistant professor or and travel expenses. equivalent) in attending the AAI annual meeting. Recipients will be reimbursed up to $1,250 for registration and travel expenses. For complete AAI Travel Award and Grant Chambers-eBioscience Memorial Award application details, visit www.AAI.org/Awards. Established to honor the memory of AAI member Dr. Cynthia Chambers, this award is intended to advance the career of an early The 2015 AAI Awards will be presented in conjunction with career scientist who attends the AAI annual meeting and presents ™ an outstanding abstract specifically in the area of cancer biology. IMMUNOLOGY 2015 The award recipient will receive a $1,000 cash award and a certificate May 8–12, 2015 • New Orleans, Louisiana during an awards presentation program at the AAI annual meeting. This award is generously supported through a grant from eBioscience, Questions? Contact AAI at 301-634-7178 an Affymetrix Company. or [email protected] 4 AAI Newsletter Winter 2014-2015

Imm2015_CFAwardApp.indd 1 10/1/14 12:03 PM Members in the News Four AAI Members Elected to Advancement of Science and the American Academy of Microbiology, and foreign member of the Indian National Institute of Medicine Academy of Sciences. He has served on multiple National Institutes of Health (NIH) study sections and as a member AAI members Rafi Ahmed (AAI ’84), Arturo Casadevall of the National Cancer Institute (NCI) Board of Scientific (AAI ’98), James E. Crowe, Jr. (AAI ’99), and John J. Counselors. His additional review and advisory panel O’Shea (AAI ’84) were elected this fall to the Institute of appointments include service for the HIV Vaccine Trials Medicine (IOM). Election to the IOM is considered one of Network, Pediatric Dengue Vaccine Initiative (Gates the highest honors in the fields of health and medicine and Foundation), International AIDS Vaccine Initiative Advisory recognizes individuals who have demonstrated outstanding Committee, Government of India’s Ministry of Science, professional achievement and commitment to service. National Multiple Sclerosis Society, Oregon Regional Primate Research Center, Baylor School of Medicine’s Center for AIDS Rafi Ahmed, Ph.D., Research, AIDS Etiology and Pathogenesis Area Review Panel Director, Emory Vaccine (Office of AIDS Research, NIH), Virology Study Section (NIH), Center; Georgia Research and the United States Environmental Protection Agency Alliance Eminent Scholar; Biotechnology Science Advisory Committee. He has served Professor, Department as editor-in-chief of Microbial Pathogenesis and held editorial of Microbiology and board appointments for the Journal of Virology, Microbial Immunology, Emory Pathogenesis, Virology, and Immunity. University School of Medicine His additional professional honors and appointments include: Drexel Prize in Immunology, Drexel University; Rafi Ahmed’s research Dan H. Campbell Memorial Lecture, Asilomar, CA; Janeway addresses the development Lecture, Yale University; Stuart Memorial Lecture, Brown of T and B cell memory and University; Cepero Memorial Lecture, University of Miami, FL; the mechanisms by which Rafi Ahmed Julius Stone Lecture, Society for Investigative Dermatology; viruses persist by evading Baruj Benacerraf Lecture in Immunology, Harvard or suppressing the immune University; Calame Lecture, ; Keynote system, with the goal of better understanding host–pathogen Lecture, Conference for Immunology Day 2009, Montreal, interactions and using this knowledge to develop vaccines. Canada; Bassford Lecture, University of North Carolina at His work on lymphocyte memory has been influential in Chapel Hill (UNC); Dolman Lecture, University of British + understanding the differentiation of CD8 memory T cells, Columbia; Keynote Lecture, Immunologic Memory and beginning with the discoveries that memory was much Host Defense, Keystone, CO; Keynote Lecture, Prevention longer lived than previously anticipated and could persist of HIV/AIDS, Keystone, CO; Keynote Lecture, Association in the absence of antigen. His group also identified T cell of Scientists of Indian Origin in America, Denton, TX; Idaho exhaustion, which can occur in chronic viral infections, such State University Distinguished Alumnus Award; Hepatitis as HIV-1, and found that blockade of programmed death 1 B Foundation Bruce Witte Distinguished Lecturer; Thaler (PD-1) could rejuvenate exhausted T cells. This discovery Honorary Lecture, Aeras Global TB Vaccine Foundation; 45th has led to clinical development of PD-1 blockade, which is Annual J.S. and H.R. Blumenthal Memorial Lectureship; showing promise for the treatment of chronic infections and Dean’s Distinguished Faculty Lecture and Award, Emory cancer. Dr. Ahmed and his lab colleagues are now expanding University School of Medicine; Thomas J. Matthews Endowed their focus to address additional inhibitory receptors and the Lectureship, Duke University; Keynote Lecture, Basic Aspects roles of other cell types in chronic viral infection. Their work of Tumor Immunology, Keystone, CO; Russell S. and Rae on humoral memory is currently focusing on mechanisms Weiser Endowed Lecture in Immunology, University of that regulate the generation of broadly neutralizing Washington, Seattle; Albert E. Levy Scientific Research Award, following influenza vaccination in hopes of developing a Emory University; Neal Nathanson Lectureship, University universal influenza vaccine. of Pennsylvania; NIH Director’s Lecture (Dyer Lecture); 3rd Ahmed is a past AAI Distinguished Lecturer, major Merle Sande Lecture, Gladstone Institute of Virology and symposium chair, and major symposium speaker at the Immunology, San Francisco; Tadeusz J. Wiktor Memorial AAI annual meeting and has served as a member of the AAI Lecture, Wistar Institute; Visiting Lamb Professor, Vanderbilt Nominating Committee and as an AAI Advanced Course University School of Medicine; Harry Weaver Neuroscience faculty member. He is a member of the National Academy Scholar, National Multiple Sclerosis Society; Ryan Foundation of Sciences, a fellow of the American Association for the Scholar, Harvard University; Osmania University Merit

6 AAI Newsletter Winter 2014-2015 Scholarship; and Government of India National Merit based on the association between a journal’s impact factor Scholarship. and retraction rate, and as a supporter of the recruitment of Ahmed holds a B.Sc. degree (chemistry) from Osmania women and minority students into scientific disciplines. University in his native Hyderabad, India, as well as B.S. and A member of the AAI Minority Affairs Committee (MAC), M.S. degrees (microbiology) from Idaho State University. He Casadevall is a past presenter of the MAC Guest Lecture at earned his Ph.D. from Harvard University and completed the AAI annual meeting (2014) and has served as a reviewer postdoctoral training at Scripps Clinic and Research for The Journal of Immunology. He has actively trained and Foundation. In 1984, he was appointed an assistant professor mentored a significant number of minority scientists, and at the UCLA School of Medicine, where he rose to full himself served as a role model of success. He is the first professor before joining Emory in 1995. Hispanic department chair at the Albert Einstein College of Medicine (“Einstein”) and has been recognized by the Arturo Casadevall, M.D., Hispanic Center for Excellence at Einstein for training Ph.D., Chair, Department minority students. Among Casadevall’s trainees, nearly half of Microbiology and are members of underrepresented minority groups and more Immunology; Leo and Julia than half are women. Forchheimer Professor Casadevall has served on numerous review/advisory of Microbiology and panels for the National Institutes of Health, including at Immunology; Professor, NIAID (Board of Scientific Counselors, Blue Ribbon Panel on Department of Medicine Biodefense Research, Immune Epitope Database Scientific (Infectious Diseases); Advisory Board, the Institut Pasteur, Invasive Aspergillosis and Director, Center for Animal Models Panel, Strategic Plan Task Force), NCI, and Immunological Sciences, NHLBI, as well as for the National Academy of Sciences Albert Einstein College of (including National Science Advisory Board for Biosecurity), Medicine Arturo Casadevall Centers for Disease Control and Prevention, Lawrence Arturo Casadevall’s Livermore National Laboratory, National Research Council, research straddles basic National Science Foundation, National Cooperative Drug immunology and microbial pathogenesis. Dr. Casadevall Discovery Group, Burroughs Wellcome Fund, St. Jude became interested in the problem of fungal infections after Fellowship for Pediatric Infectious Diseases, and Abbott witnessing first hand the ravages of the AIDS epidemic in Laboratories Award in Clinical and Diagnostic Immunology. the mid-1980s. He worked with his postdoctoral mentor Dr. A founding editor and editor-in-chief of mBio, Casadevall Matthew Scharff (AAI ‘64) to develop passive therapy has held editorial appointments with the Journal of Clinical against Cryptococcus neoformans, which led to the discovery Investigation, Journal of Experimental Medicine, Nature of new mechanisms of antibody action. To understand other Reviews in Microbiology, Faculty of 1000, Future Microbiology, immunological questions he explored basic mechanisms of BMC Infectious Diseases, Expert Opinion on Emerging Drugs, fungal pathogenesis. His lab discovered that C. neoformans Current Opinion in Microbiology, Emerging Infectious Diseases, was a facultative intracellular pathogen with a novel Revista Iberoamericana de Micología, Infection and Immunity, replicative strategy that included activation of the cell cycle. International Journal of Infectious Diseases, and Journal of Some of Casadevall’s work has translated into therapeutics Medical and Veterinary Mycology and has served as a reviewer that have been tested in the clinic. His studies delving into the for over 40 journals. He is an elected member of the relationship between C. neoformans melanin production and American Society for Clinical Investigation, American virulence of this organism ultimately led to the development Association of Physicians, and Interurban Clinical of antibody-based radioimmunotherapy to treat melanoma. Club; fellow of the American Academy of Microbiology, Casadevall’s research now branches out beyond fungal Infectious Disease Society of America, and American immunity, encompassing studies on the development of a Association for the Advancement of Science; and has wide range of antibodies that are efficacious against diseases served as president of the Medical Mycology Society of ranging from anthrax to tuberculosis to cervical cancer. the Americas. Casadevall’s passion for science extends beyond his His additional career honors include: Founders prolific lab career (which has resulted in several hundred Distinguished Service Award, American Society for citations), to advocacy for good scientific practices in the Microbiology (ASM); Faculty Mentoring Award, Albert public realm. He is nationally recognized as a proponent Einstein College of Medicine; ASM William Hinton of scientific peer review reform and scientific integrity, as Award (for mentoring scientists from underrepresented the co-creator of the “retraction index,” a scoring system

6 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 7 Members in the News (continued) groups); NIH MERIT Award; Rhoda Benham Award, has used strategies, such as phage display combinatorial Medical Mycology Society of the Americas; Maxwell libraries, hybridomas, and high-throughput sequence analysis L. Littman Award in Mycology; Solomon A. Berson to dissect structural and functional characteristics of antiviral Medical Alumni Achievement Award in Basic Science, antibodies, and analyses of virus-neutralizing antibodies from (NYU) School of Medicine; survivors of historical pandemics. His early work, producing Kass Lecture, Infectious Disease Society of America; targeted, recombined antibody Fab fragments in bacteria, Burroughs Wellcome Visiting Professorship, University of demonstrated that these molecules could neutralize viruses Wisconsin; Sam Rosen Award, Einstein; Leo M. Davidoff in these organisms, leading to investigations for the use of Society (for outstanding teaching), Einstein; Foundation antibodies as therapeutic agents against infectious diseases. for Microbiology Lectures Program; Burroughs He also pioneered studies in the field of respiratory syncytial Wellcome Fund Developmental Therapeutics Award; virus (RSV) research, demonstrating that maternal antibodies James S. McDonnell Scholar Award; Pfizer Postdoctoral present in newborns hinder the ability of infants to mount Fellowship Award; Montefiore Fellow of the Year Award; effective antibody responses in response to immunization Medical Scientist Training Program Fellowship; Salk against RSV. Dr. Crowe’s lab identified a large number Graduate Scholarship; and undergraduate honors of live, attenuated RSV vaccine candidates for use in the including the Stanley Konkol Memorial Award and development of more efficacious vaccines to this virus. His Chemistry Department Service Award. In 2013 he ambitious research program extends beyond RSV studies delivered the Kinyoun lecture at the NIH. and targets the development of vaccines and therapeutics for A chemistry graduate of Queens College, CUNY, a broad spectrum of pathogens, including Ebola, influenza, Casadevall received his M.S., Ph.D. (biochemistry – Dengue, HIV, West Nile, and smallpox viruses. In addition to mentor: Loren Day), and M.D. degrees from NYU. He these endeavors, his lab currently focuses on learning how completed his medical internship and in viral proteins and viruses traffic within cells. internal medicine at ‐ NYU Medical Crowe is a member of the AAI Program Committee and Center, a postdoctoral fellowship in infectious diseases has served as a reviewer for The Journal of Immunology. He at Albert Einstein/Montefiore Medical Center, and has held editorial board appointments for Nanomedicine: postdoctoral fellowship in cell biology (Matthew Nanotechnology, Biology and Medicine; WIRES: Nanomedicine Scharff lab) at Albert Einstein College of Medicine. He and Nanobiotechnology; PLoS Pathogens; Nanomedicine; joined the Einstein faculty as an assistant professor Virology; Journal of Virology; Faculty of 1000; Pediatric of medicine and of microbiology and immunology in Infectious Diseases Journal; Seminars in Pediatric Infectious 1992; he was appointed associate professor in 1996 and Diseases; and Proceedings of the National Academy of Sciences full professor in 2001 and has served as Department of USA and has served as a reviewer for more than 30 journals. Microbiology and Immunology chair since 2006. His past Crowe has been a member of multiple NIH study Einstein appointments include director of the Division sections and served on numerous other review and of Infectious Diseases and Selma and Jacques Mitrani advisory panels for NIH, U.S. Department of Defense, Professor in Biomedical Research. U.S. Department of Homeland Security, U.S. Civilian Research and Development Foundation, March of James E. Crowe, Jr., M.D., Dimes, Thrasher Foundation, World Health Organization, Ann Scott Carrell Professor, Wellcome Trust , University of Siena, Swiss National Science Pediatric Infectious Foundation, BioAdvance/Greenhouse, Health Research Disease; Professor of Board of Ireland, Maryland Industrial Partnerships, , Microbiology, Genome British Columbia, Society for Pediatric Research and Immunology; and (SPR), Pediatric Infectious Diseases Society, U.S./Israel Director, Vanderbilt Binational Science Foundation, U.S. Immunodeficiency Vaccine Center, Vanderbilt Network, Infectious Diseases Society of America, University Medical Center American Institute of Biological Sciences–U.S. Army James Crowe’s research Medical Research and Materiel Command, Singapore elucidates the mechanisms Agency for Science, Technology and Research, New York behind the generation Influenza Center of Excellence, Duke–National University of effective antibody James Crowe, Jr. of Singapore Program, M. J. Murdock Charitable Trust, responses in response Danish National Research Foundation, Danish Council to viral infection. His lab for Strategic Research, Instituto Pasteur–Fondazione

8 AAI Newsletter Winter 2014-2015 Cenci Bolognetti (Italy), Pediatric Academic Societies/ Vanderbilt University Medical Center as a clinical fellow and Asian SPR Joint Meeting and Eastern SPR Annual Meeting, instructor in 1995. He was appointed an assistant professor Hong Kong Special Administrative Region Government in 1996, associate professor in 2001, and full professor Food and Health Bureau, Pediatric Academic Societies in 2004; his Vanderbilt appointments have included the Annual Meeting, Sigma Delta Epsilon Graduate Women in Ingram Professor of Cancer Research. Science Program, Swiss National Science Foundation, New York Capital Research Alliance, French National Research John J. O’Shea, M.D., Agency, Israel Science Foundation, Medical Research Scientific Director, National Council, U.K., International Pediatric Research Foundation, Institute of Arthritis and Human Vaccines Project Working Group, U.S.–Japan Musculoskeletal and Foundation, and U.S.–Japan Cooperative Medical Sciences Skin Diseases, National Program. Institutes of Health Crowe has received multiple Vanderbilt University John O’Shea’s lab honors, including Mentor of the Year Award (Vanderbilt studies signal transduction Postdoctoral Association), Chancellor’s Research Award, pathways that regulate Ernest W. Goodpasture Faculty Research Award, F. cytokine signaling and Peter Guengerich Award for Mentoring Postdoctoral how these pathways Fellows, Teacher of the Year Award (School of Medicine affect differentiation and activation of immune Interdisciplinary Graduate Program), and Turner Scholar John O’Shea Award. His additional career honors include: Norman J. cells. In particular, Dr. Siegel New Member Outstanding Science Award, American O’Shea has detailed many Pediatric Society; Outstanding Investigator Award, elements of Janus kinase (Jak) and signal transducer and American Federation for Medical Research; America’s activator of transcription (STAT) pathways and their role Top Pediatricians, Consumers Research Council; E. Mead in immunomodulation and disease. His group cloned and Johnson Award for Excellence in Pediatric Research, SPR; characterized Jak3, a nonreceptor tyrosine kinase, and Oswald Avery Award for Early Achievement, Infectious demonstrated the role mutations in this molecule play in Diseases Society of America; Judson Daland Prize for autosomal recessive severe combined immunodeficiency. Outstanding Achievement in Patient-Oriented Clinical His research on Jaks has yielded a number of patents and Research, American Philosophical Society; Young led to the development of immunomodulatory drugs Investigator Award, SPR; Young Investigator Award, that have the potential to treat a variety of diseases from Pediatric Infectious Diseases Society; Dade MicroScan cancer to autoimmunity. His group also examines the Young Investigator Award, ASM; Basil O’Connor Scholar contribution of Jak-STAT signaling to cytokine regulation Research Award, March of Dimes; Pfizer Faculty Scholar, of CD4+ T helper (Th) cell differentiation, including the Pfizer, Inc.; Edward Curnen Award, UNC Pediatrics; requirement for STAT-1 in follicular Th cell development, Outstanding Pediatric Resident, Wake Medical Center; STAT-3 in Th17 cell differentiation, and STAT-4 in Th1 cell Edward Stuart Scholarship (full four-year undergraduate differentiation. Importantly, his group collaborated with merit scholarship), Davidson College. others to show that STAT-3 mutations that cause defective Th17 cell differentiation contribute to the development He served on the council of the SPR American and of Hyperimmunoglobulin E syndrome. Most recently, is a member or fellow of the American Academy of O’Shea’s work has delved further into CD4+ Th subset Microbiology, American Association for the Advancement differentiation, analyzing the epigenetic events that of Science, American Pediatric Society, Association of determine the plasticity of Th cell commitment. American Physicians, American Society for Clinical Investigation, Federation for Medical Research, Infectious O’Shea has served as a major symposium chair Diseases Society of America, American Society for Virology, and speaker at the AAI annual meeting and as an and American Society of Microbiology. associate editor for The Journal of Immunology. His additional career honors and appointments include: A graduate of Davidson College, Crowe earned his fellow, American Association for the Advancement of M.D. from UNC School of Medicine, where he completed Science; U.S. Public Health Service Physician Researcher his internship and residency in pediatrics. He received of the Year Award; Paul Bunn Award in Infectious postdoctoral training in the Respiratory Viruses Section of Disease; Lee C. Howley Prize in Arthritis Research; the Laboratory of Infectious Diseases at NIAID (mentors: Irish Society for Immunology Public Lecture Award; Robert Chanock and Brian Murphy) before joining Ross Prize in Molecular Medicine; Daniel Drake Medal;

8 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 9 Members in the News (continued)

NIH Director’s Award (three times); elected member, and became scientific director of the NIAMS Intramural American Association of Physicians; elected member, Research Program in 2005. O’Shea has served as acting American Society for Clinical Investigation; World’s Most director of the NIH Center for Regenerative Medicine Influential Scientific Minds (Immunology 2002- 2014, and is a professor in the Department of Pathology at the Thomson Reuters); NIAMS Mentoring Award; NIH “Make University of Pennsylvania. a Difference” Office of Equal Opportunity Award; co- founder, NIH/Oxford/Cambridge program in biomedical IOM science; member, NIH–UPenn Immunology Program; Established in 1970 by and adviser, Howard Hughes Medical Institute Scholars. the National Academy of O’Shea has served on the editorial boards of Sciences as both an honorific Immunity, Journal of Experimental Medicine, Journal membership organization and of Biological Chemistry, and Blood and has presented an advisory organization, IOM numerous invited lectureships at universities and serves as a national resource international meetings in the United States, Canada, for independent, scientifically Europe, and Asia. He is board certified in internal informed analysis and medicine and allergy and immunology. recommendations on health issues. New members are elected by current active members through a selective process that recognizes A Phi Beta Kappa graduate of St. Lawrence University, individuals who have made major contributions to the advancement O’Shea received his M.D. from the University of Cincinnati of the medical sciences, health care, and public health. With their before serving as an intern and resident in internal election, members make a commitment to volunteer their service on medicine at the State University of New York Upstate IOM committees, boards, and other activities. Projects during the Medical University. He later received subspecialty past year include studies of the benefits of including physical activity training in allergy and immunology at NIH and additional in the school environment, direct health outcomes of sodium intake, postdoctoral training in the Cell Biology and Metabolism regional variations in Medicare spending, child abuse and neglect in Branch in the National Institute of Child Health and the United States, improved delivery of cancer care, the commercial Human Development. After subsequently establishing sexual exploitation and sex trafficking of minors in the United States, his own research group in the National Cancer Institute post-deployment needs of Iraq and Afghanistan service members, in 1989, he moved to NIAMS in 1994 as chief of the gun violence research priorities in the United States, and the Lymphocyte Cell Biology Section of the Arthritis and international problem of illegitimate and substandard medications. Rheumatism Branch. In 2002, he was appointed chief of the For more information about IOM, visit http://www.iom.edu. NIAMS Molecular Immunology and Inflammation Branch

Jane Salmon medicine and professor of obstetrics and gynecology at Weill Cornell Medical College (WCMC). Her research Receives Lupus focuses on the mechanisms of tissue injury in patients Foundation with lupus and other autoimmune diseases with the goal of characterizing determinants of disease phenotype Honors and, thereby, targets for therapy. Her laboratory identified the essential role of complement activation as a cause of Jane E. Salmon, M.D., pregnancy loss and thrombosis in the antiphospholipid AAI ’87, is a 2014 recipient syndrome (APS). To translate these findings to patients, of the Evelyn V. Hess she is currently leading the PROMISSE Study (Predictors Research Award, presented of pRegnancy Outcome: bioMarkers In antiphospholipid by the Lupus Foundation of antibody Syndrome and Systemic lupus Erythematosus), a America in recognition of multicenter, prospective observational study of pregnant Jane Salmon investigators whose work women with lupus and/or APS. The study seeks to has significantly advanced characterize predictors of pregnancy outcomes and use understanding of the these indicators to develop trials in patients at risk for causes and management of lupus. severe pregnancy complications. Salmon’s group is also Salmon is the Collette Kean Research Professor at investigating the mechanisms responsible for accelerated the Hospital for Special Surgery (HSS) and professor of atherosclerosis observed in patients with lupus and

10 AAI Newsletter Winter 2014-2015 rheumatoid arthritis. Overall, her studies have uncovered An honors graduate (psychobiology) of New York causes of pregnancy loss and organ damage in lupus, University, Salmon received her M.D. from the College identified predictors of risk for lupus-related pregnancy of Physicians and Surgeons of Columbia University, complications, kidney inflammation (nephritis), and where she was the first woman enrolled in their Medical cardiovascular disease, and pioneered new targets to Scientist Training Program. She completed her medical prevent these disorders. internship and residency at The New York Hospital and Salmon holds associate editor appointments with trained as a postdoctoral fellow in rheumatic diseases Annals of Rheumatic Diseases and Lupus, Science at the Hospital for Special Surgery (HSS). In 1983, she and Medicine and has held additional editorial board was appointed an instructor in medicine at Cornell appointments with Arthritis and Rheumatism, Lupus, University Medical College, where she later became Autoimmunity, Current Opinions in Rheumatology, and an assistant and then associate professor, including Genes and Immunity. in the immunology graduate program of the Cornell University Graduate School of Medical Sciences. Salmon has served on numerous review and advisory During the period, she also held scientist and attending panels for the National Institutes of Health, as well as physician appointments of increasing rank at New for other organizations including the American College York Presbyterian Hospital and HSS. In 1996, she was of Rheumatology (Board of Directors), Rheumatology named to her current appointments as a full professor of Research Foundation (Board of Directors), Alliance medicine of the Weill Cornell Medical College (WCMC), for Lupus Research (Scientific Advisory Board), Lupus senior scientist and attending physician at HHS, and Research Institute, Henry Kunkel Society, Clinical attending physician at New York Presbyterian. She also Immunology Society, Federation of Clinical Immunology serves as a professor in the immunology and microbial Societies (secretary-treasurer), European League pathogenesis graduate program of the Weill Cornell Against Rheumatism, Lupus Federal Working Group, Graduate School of Medical Sciences, professor of S.L.E. Foundation, New York Rheumatism Association medicine in obstetrics and gynecology at WCMC, and (president), and New York Arthritis Foundation. Collette Kean Research Chair at HSS. Her additional Salmon’s career honors include: the Carol Nachman appointments include director of the Lupus and APS Prize in Rheumatology; Virginia Kneeland Frantz ’22 Center of Excellence, director of the Lupus Registry and Distinguished Women in Medicine Award, Columbia Repository, and co-director of the Mary Kirkland Center Physicians & Surgeons Alumni Association; Nanna for Lupus Research. Swartz Lectureship, Swedish Society of Medicine; Annual Ogryzlo Research Day Visiting Professor, University of Toronto; “Best Doctors in New York,” New York magazine; George Tsokos Michael Einbender Distinguished Lectureship, University Receives of Missouri-Columbia School of Medicine; Soderberg Prize Symposium, Swedish Society of Medicine; Laura Awards from Hadad Lectureship, Georgetown University Hospital; American Theodore E. Woodward Award, American Clinical and Climatological Association; Arthur DeGraff Lecture, College of New York University School of Medicine; Eric Bywaters Rheumatology, Memorial Lecture, Imperial College of London; Edmund L. Dubois, M.D., Memorial Lectureship Award, American Lupus College of Rheumatology; Jacob Probstein Endowed Foundation Lecture in Obstetrics and Gynecology, Washington University in St. Louis; Janice M. Wiles Memorial Lecture George Tsokos George C. Tsokos, on SLE, University of Massachusetts; Kroc Visiting M.D., AAI ’81, has Professor, UCLA; Henry Christian Award for Excellence been honored with the in Research, American Federation for Clinical Research; American College of Rheumatology (ACR) Distinguished Young Women Achievers Award, National Council of Basic Investigator Award, which recognizes an ACR basic Women; Andrew W. Mellon Teacher‑Scientist; American scientist for outstanding contributions to the field of Rheumatism Association Senior Rheumatology Scholar rheumatology. In addition, Tsokos is a 2014 recipient Award; S.L.E. Foundation Fellowship. She is a member of of the Evelyn V. Hess Research Award, presented by Association of American Physicians. the Lupus Foundation of America in recognition of

10 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 11 Members in the News (continued) investigators whose work has significantly advanced scientific journals. His career honors include the NIH understanding of the causes and management of lupus. MERIT (Method to Extend Research In Time) Award; Dr. Tsokos is a professor of medicine at Harvard Lee C. Howley, Jr., Prize for Arthritis Research; the Medical School and chief of rheumatology at Beth Israel Mary Kirkland Award, Mary Kirkland Lupus Center; Deaconess Medical Center, Harvard Medical School. Distinguished Service Award, CIS; master, American His research delves into the cellular and molecular College of Physicians; fellow, American Association pathogenesis of systemic lupus erythematosus for the Advancement of Science; member, Association (SLE), with emphasis on identifying biomarkers and of American Physicians; James Leonard Award for therapeutic targets to diagnose and treat this disease. Excellence in Clinical Research, Uniformed Services Tsokos has taken a unique approach to his work, using University of the Health Sciences (USUHS); William human cells, tissues, and fluids from SLE patients to Crosby Superiority in Research Award, American College identify genetic and functional abnormalities. He then of Physicians; Philip Hench Award, Association of translates these aberrations into murine systems to Military Surgeons of the United States; William R. Felts, dissect out the specific mechanisms behind the defects M.D. Award for Excellence in Rheumatology Research and develop therapeutics to counteract them, in essence Publications, Arthritis Foundation’s Metropolitan traveling from the bedside to the bench and back again. Chapter; and member, Henry Kunkel Society. With the use of these methods, Tsokos has made seminal Tsokos has a special interest in training and contributions to the autoimmunity field by defining developing young colleagues. He directs a T32 training molecular abnormalities in SLE T cells. He has identified program in systemic autoimmunity and has mentored several defining characteristics of these cells that can numerous fellows who have attained leading positions be used as biomarkers for disease, including aggregated and/or become K award or R grant recipients. Between lipid rafts on the T cell surface, decreased T cell receptor 2003 and 2010, Tsokos ran the annual CIS summer zeta chain expression, and increased expression of school on systemic autoimmunity attended by select calcium/calmodulin-dependent protein kinase type fellows from around the world and supported through IV and the catalytic subunit of protein phosphatase an NIH/industry collaboration (R13). 2A. Tsokos’ work also extends to the investigation of A native of Greece, Tsokos received his medical aberrant T cell populations, signaling molecule activity, degree and doctor of sciences degree in biostatistics cytokine secretion, and epigenetic events that could from the National University of Athens in Athens, affect disease development or resolution. Other projects Greece, where he also did resident training in internal in the lab are oriented towards understanding the medicine. He undertook additional resident training mechanisms of tissue injury in autoimmune disease in internal medicine at the Combined Veterans and defining therapies to minimize the damage caused Administration Medical Center-Georgetown University during disease pathogenesis. His research has led to the Program in Washington, D.C., and completed additional identification of a number of therapeutic targets now in postdoctoral training in immunology (as a Fogarty different stages of development. International Center Fellow) and rheumatology in Tsokos has served as an associate and section editor the Arthritis and Rheumatism Branch of the National for The Journal of Immunology and as an abstract Institute of Arthritis, Diabetes, and Digestive and Kidney programming chair for the AAI annual meeting. He has Diseases at the National Institutes of Health. In 1983, he served as member or chair on numerous review panels was appointed a clinical professor in the Department for federal agencies including the National Institutes of Medicine at USUHS, where he would rise to full of Health, Department of Veterans Affairs (VA), and professor in 1991 and serve as vice chair for research. He Department of Defense (DoD), as well as for other also served as chief of the Department of Cellular Injury organizations including the Alliance for Lupus Research. at the Walter Reed Army Institute of Research. He was A past president of the Clinical Immunology Society named to his current Beth Israel Medical Center and (CIS), of which he served on numerous committees, Harvard Medical School appointments in 2007. Tsokos has served on multiple committees of the American College of Rheumatology and American College of Physicians. He has served as consulting editor of the Journal of Clinical Investigation, serves as editor-in-chief of Clinical Immunology, and held editorial appointments with dozens of additional

12 AAI Newsletter Winter 2014-2015 IN MEMORIAM

Herman N. Eisen, M.D., AAI ’51 (1918–2014)

“I’ve always enjoyed seeing medicine as an outsider and following it, but I enjoy science more... The kind of science I enjoy is dispelling ambiguities. I can’t stand ambiguity. Getting insight to a problem can be pretty rewarding.”

Herman Eisen, AAI Oral History Project interview (May 4, 2012)

AAI extends condolences to the family, The following tribute was published friends, and colleagues of renowned by MIT and appears with the kind immunologist and past AAI president permission of that institution. Herman N. Eisen, M.D., AAI ’51, who died on November 2 at the age of 96. He was the oldest and second-longest tenured AAI Herman Eisen, Professor member at the time of his death. Emeritus of Biology, Dies at 96 An emeritus professor of biology at Eisen was a pioneering immunologist and Massachusetts Institute of Technology longstanding member of MIT’s cancer (MIT), whose active research career research community. spanned six decades and extended to the Kevin Leonardi, Koch Institute end of his life, Dr. Eisen is perhaps best November 13, 2014 known for groundbreaking research in Herman Eisen, a professor emeritus of which he described affinity maturation, the biology and founding member of the immune system’s ability to adjust antibody MIT Center for Cancer Research, died production to better identify and neutralize Herman Eisen November 2 at age 96. invading pathogens after infection. Over a 70-year career, Eisen forged The recipient of the AAI Lifetime Achievement Award a path as a pioneering immunologist whose research has (1997) and AAI Behring Heidelberger Award (1993), Eisen significantly shaped the field. He joined the MIT faculty in was a member of the AAI Council from 1964 to 1971, 1973, having been recruited as a founding member of MIT’s including as AAI president from 1968 to 1969. He served on Center for Cancer Research (now the Koch Institute for the AAI Awards Committee and AAI Nominating Committee Integrative Cancer Research). (including as chair of both) and on additional AAI bodies, including the Blue Ribbon Panel, Committee for Liaison Eisen retired from MIT in 1989, albeit only in the official with DRG [Division of Research Grants, National Institutes sense: As a professor emeritus, he maintained an active of Health (NIH)], Liaison Committee with Research Granting laboratory and continued to research, publish, and advise Agencies, and Long Range Planning Committee (chair). students and postdocs until his passing. In all, Eisen spent He was a member of the editorial board of The Journal of 41 years at MIT, during which he taught, mentored, and Immunology and served as AAI representative to the board collaborated with thousands of students, faculty members, of the Federation of American Societies for Experimental and staff. Biology. For highlights of his AAI service and career achievements Early years and to view Dr. Eisen’s 2012 interview for the AAI Oral History Born in 1918 in Brooklyn, New York, Eisen developed Project, visit www.aai.org/About/History/Notable_Members/ a keen interest in science at an early age, when a high Presidents/Eisen_Herman.html. school chemistry class helped frame his perception of the Eisen was a member of the National Academy of Sciences world as a collection of atoms and molecules. Eisen began and the Institute of Medicine of the National Academies and premedical studies at New York University (NYU) in 1934, a fellow of the American Academy of Arts and Sciences. but halfway through his undergraduate career he needed to

12 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 13 IN MEMORIAM

Herman N. Eisen, M.D., AAI ’51 (continued) (1918–2014)

leave school — and his position as first baseman on NYU’s Physics, Chemistry, and Biological Engineering. baseball team — after developing tuberculosis. Though “Understanding this evolutionary process is critical for Eisen’s TB kept him out of school for one year, the illness vaccine design, and affinity maturation is also mimicked in sparked a curiosity about the immune system that would countless academic laboratories and companies to design endure for the rest of his life. antibody-based therapies.” Eisen returned to NYU to complete his bachelor’s degree, and he then enrolled at the university’s medical Joining the MIT cancer research community school. He graduated with an M.D. in 1943 and then In response to the signing of the National Cancer worked as an assistant in the pathology department at the Act of 1971, MIT tasked Nobel Prize-winning biology Columbia University College of Physicians and Surgeons professor with establishing and leading a before going back to NYU for his residency. new MIT Center for Cancer Research. Wanting to include Eisen had a strong interest in basic science research, cancer immunology as a focus of this new center, Luria particularly in trying to better understand the body’s approached Eisen about joining as a founding faculty immune system. Though career options for physician- member. Eisen accepted the role, and arrived at MIT in scientists had historically been limited, the federal 1973 as a professor in the Department of Biology. government began to increase its funding of biomedical Eisen brought his immunology expertise to MIT’s new research through the National Institutes of Health (NIH) cancer center to study how cancer cells evade the body’s following World War II. Seizing these new opportunities, natural immune response. Much of his work focused on Eisen became one of the first recipients of an NIH studying myeloma tumors in mice and screening their fellowship, which supported his research on sulfonamide- associated proteins. He found that if he used myeloma induced antibodies at NYU. These investigations helped proteins from one mouse to immunize other mice from him and colleague Fred Karush to determine the number of the same strain, they were resistant when challenged antigen-binding sites on antibodies. with cancer cells. After his two-year NIH fellowship, Eisen worked briefly Eisen and his laboratory went on to study how CD8 at the Sloan Kettering Institute before returning once again T cells develop into cytotoxic, or “killer,” T cells and to NYU as a faculty member. Inspired by the work of his long-lived memory T cells. Therapeutic vaccines that recently deceased role model, physician-scientist Karl exploit CD8 responses have not yet been developed for Landsteiner, he studied immune reactions of the skin. In human populations; existing immunotherapies rely on doing so, he clarified the basis for certain allergic responses helper T cells and other immune cells, and they do not and showed that only those chemicals capable of forming mount the same aggressive offense against targets. Eisen covalent bonds to skin proteins could cause a characteristic was working to understand and overcome the barriers to itchy rash. creating effective CD8 vaccines, and his research on the In 1955, Washington University in St. Louis (WUSTL) subject was of particular importance to the advancement recruited Eisen to join the faculty of its School of Medicine. of cancer immunology. As part of this research, Eisen There, he served as dermatologist-in-chief for five years collaborated closely with Koch Institute faculty members before moving to the Department of Microbiology to serve Jianzhu Chen and Richard Young, who is also a member as chair. While at WUSTL, Eisen published groundbreaking of the Whitehead Institute. research in which he described affinity maturation: the “Herman’s lifelong pursuit of science, even to the very process by which activated B cells produce antibodies with last day of his life, has been an inspiration to many of us,” an increasingly higher affinity for invading pathogens after says Chen, the Ivan R. Cottrell Professor of Immunology. infection. This process is fundamental to the development “He was a great human being with a great attitude and a of potent immune responses. clear mind. He will be missed greatly.” “Our understanding of affinity maturation begins with As a fixture of MIT’s cancer research community since Herman’s papers,” says Arup K. Chakraborty, director of its formal inception, Eisen could, in recent years, often be MIT’s Institute for Medical Engineering and Science and found in his second-floor Koch Institute office consulting the Robert T. Haslam Professor in Chemical Engineering, with students and younger investigators.

14 AAI Newsletter Winter 2014-2015 “Herman was a true treasure: an inspiring colleague, a Eisen was elected to the American Academy of Arts and caring mentor, and a wonderful human being,” says Tyler Sciences in 1965, the National Academy of Sciences in 1969, Jacks, director of the Koch Institute and the David H. Koch and the Institute of Medicine of the National Academies Professor of Biology. “We all aspire to be Herman Eisen.” in 1974. He received numerous other awards and honors Other colleagues remember Eisen not only as a throughout his career, including the Behring-Heidelberger groundbreaking immunologist but also as a hardworking Award from The American Association of Immunologists, collaborator and a generous man of integrity. He continued to an Outstanding Investigator Award from the National be an active scientist and had been working with Chakraborty Cancer Institute, and the Lifetime Service Award from The on a paper until his passing. American Association of Immunologists, of which he served as president from 1968 to 1969. “Herman was a giant in the field of immunology, with many seminal discoveries,” Chakraborty says. “He was also Eisen is survived by his wife Natalie; their children, Ellen, the kindest and most generous and moral person I have Jane, Jim, Tom, and Matthew; and 12 grandchildren. known. Until the end, he was working on scientific problems with junior colleagues and students who benefited from his Memorial donations may be made to the Marine wisdom. I am lucky to have worked with this great scientist Biological Laboratory (connect.mbl.edu/donate) in Woods and wonderful human being.” Hole, Massachusetts. “Herman was a wonderful colleague and a terrific See also: Michael C. Purdy, “Obituary: Herman Eisen, person with the highest integrity — a true mensch,” adds 96, former head of molecular microbiology,” Newsroom, Alan Grossman, the Praecis Professor of Biology and head November 13, 2014, Washington University in St. Louis, of MIT’s biology department. “We will miss his wisdom, https://news.wustl.edu/news/Pages/27687.aspx thoughtfulness, and vitality.” Future AAI Annual Meetings Future AAI Annual Meetings Mark Your Calendar for the Premier Annual Immunology Event! Mark Your Calendar for the Premier Annual Immunology Event! 2015 2016 2017

IMMUNOLOGY 2015™ IMMUNOLOGY 2016™ IMMUNOLOGY 2017™ IMMUNOLOGYMay 2015 8–12™ May 13–17™ May 12–16™ New Orleans, Louisiana IMMUNOLOGYSeattle, Washington 2016 IMMUNOLOGYWashington, 2017 D.C. May 8–12 May 13–17 May 12–16 New Orleans, Louisiana Seattle, Washington Washington, D.C. 14 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 15

AAI_FutureMtg2015_HPH_2.indd 1 3/19/14 7:01 AM

AAI_FutureMtg2015_HPH_2.indd 1 3/19/14 7:01 AM Digital Image Dos and Don’ts IN MEMORIAM

Stephen L. Kaattari, Ph.D., AAI ’88 Before preparing manuscript fi gures, please read the Information for Authors at http://www.jimmunol.org/site/misc/authorinstructions.xhtml#mspreparation (1951–2014)

1. Do not erase any part of the image, including the background. AAI member Stephen Kaattari, retired in January 2014. He served as Chair Ph.D., a professor in the Department of of the Department of Environmental and YES NO Environmental and Aquatic Animal Health Aquatic Animal Health (currently Aquatic at the College of William & Mary’s Virginia Health Sciences) from 2002 to 2004. Prior Institute of Marine Science (VIMS), died on to joining VIMS, Steve was a professor of November 11, 2014, at the age of 63. microbiology at Oregon State University, Before his January 2014 retirement, where he served on the faculty for 10 years. Dr. Kaattari and his laboratory colleagues Steve was a highly respected and 2. Do not use excessive contrast that removes background. explored the basic molecular, cellular, internationally recognized researcher, as well and immunochemical aspects of teleost as an extraordinary teacher and mentor. His YES NO immune system function. Their insights research program melded basic research in were applied to the understanding of immunology with applied goals to provide disease resistance and pathogenesis, as well innovative and practical new tools for the as the development of immunodiagnostics scientific community and the public. His and vaccines for aquaculture. An Stephen Kaattari research has provided new understanding of additional, more recent line of inquiry focused on basic immune functions and has produced vaccines for use in the development of monoclonal antibody probes for aquaculture. His more recent work included development of 3. Make any adjustments to brightness or contrast equally across the entire image. incorporation into real-time sensor platforms to monitor the real-time sensor platforms that are now being used to analyze presence and flux of pollutants, toxins, and pathogens within pollutants in Chesapeake Bay. Products from his research YES NO the estuarine environment. have resulted in new patents in the United States and Britain Prior to his two decades on the William & Mary faculty, and have led to new areas of research that continue today. Kaattari served as a professor of microbiology at Oregon State Steve advised 20 graduate students, 11 postdoctoral trainees, University. He received his B.S. and Ph.D. degrees from the numerous undergraduates, and served on more than 75 Entire image lightened. Contrast changed in three small areas only. University of California, Davis, and completed his postdoctoral graduate-student committees. training at Oregon State. His career honors and appointments During Steve’s tenure at VIMS, he secured more than $8 included the Special Achievement Award of the American million in competitive extramural grants and contracts to 4. Indicate any splicing of data from a single experiment by contrasting (black or white) Fisheries Society and the James and Mildred Oldfield Team support his research program. He authored or co-authored lines; state the manipulation in the legend. Award, Oregon State University; editorial board/reviewer more than 90 technical articles and books, and reviewed more Images from different experiments should not be spliced to form a new single image. service for Fish and Shellfish Immunology and Diseases of than 350 proposals and over 400 manuscripts for the scientific Aquatic Organisms; and interdisciplinary collaborations community. He also served on numerous advisory committees YES NO with the National Fish Health Research Laboratory (U.S. for professional societies. In 2004, Steve was awarded a special Geological Survey), the National Center for Cool and Coldwater achievement award by the American Fisheries Society. Aquaculture (USDA), and the schools of veterinary medicine Most recently, Steve chaired the faculty search committee at the University of Georgia and Michigan State University. that ultimately led to two new outstanding hires at VIMS. He In addition to AAI, Kattaari was a member of the American Splicing not marked. was very dedicated to serving the Institute and was excited Society for Microbiology and the International Society for to play a part in rebuilding the VIMS faculty following several Development and Comparative Immunology. recent retirements. 5. Crop gels and blots conservatively, retaining important bands. AAI extends condolences to Dr. Kattaari’s family, friends In a letter to the VIMS community, Dean and Director John and colleagues. The following remembrance appears courtesy Wells wrote “I and the entire VIMS community will miss Steve YES NO of VIMS. tremendously, but he will not be forgotten, as his legacy will live Tribute to Professor Stephen Kaattari on at VIMS. My deepest sympathies go out to his wife, Ilsa, and their family.” by VIMS Staff, November 12, 2014 A memorial and celebration of life for Dr. Kaattari was held Dr. Stephen L. Kaattari, CSX Professor of Marine Science, Monday, December 8, 2014, at the William & Mary Alumni Emeritus at the Virginia Institute of Marine Science, passed House. Donations may be made to the Williamsburg Heritage away on November 11, 2014. Humane Society, Habitat for Humanity, or the American • All images submitted to e Journal of Immunology must accurately represent the original data. Steve joined the William & Mary faculty in 1993 and had Heart Association. • Original data (digital fi les, autoradiographs, fi lms, etc.) for all experiments should be fully annotated, secured, and retrievable for up to 10 years. 16 AAI Newsletter Winter 2014-2015 • The original image fi le (raw data fi le) should be kept in an unprocessed and non-compressed fi le format. • Figures that are compiled into multi-fi gure panels should be kept individually. Digital Image Dos and Don’ts

Before preparing manuscript fi gures, please read the Information for Authors at http://www.jimmunol.org/site/misc/authorinstructions.xhtml#mspreparation

1. Do not erase any part of the image, including the background. YES NO

2. Do not use excessive contrast that removes background. YES NO

3. Make any adjustments to brightness or contrast equally across the entire image. YES NO

Entire image lightened. Contrast changed in three small areas only.

4. Indicate any splicing of data from a single experiment by contrasting (black or white) lines; state the manipulation in the legend. Images from different experiments should not be spliced to form a new single image. YES NO

Splicing not marked.

5. Crop gels and blots conservatively, retaining important bands. YES NO

• All images submitted to e Journal of Immunology must accurately represent the original data. • Original data (digital fi les, autoradiographs, fi lms, etc.) for all experiments should be fully annotated, secured, and retrievable for up to 10 years. 16 AAI Newsletter Winter 2014-2015 • The original image fi le (raw data fi le) should be kept in an unprocessed and non-compressed fi le format. • Figures that are compiled into multi-fi gure panels should be kept individually. AAI Outreach Program

he AAI Outreach Program, now in its fourth year, contributes to the career development of young scientists by Toffering awards for trainees and young principal investigators at eligible, member-organized conferences across the United States. This past fall, AAI sponsored oral and poster presentation awards at four immunology meetings: Colorado Immunology Conference, Northern Immunological Mountain Society Annual Meeting, La Jolla Immunology Conference, and New York Immunology Conference.

Colorado Immunology Conference (CIC) Left: Diane Griffin delivering the Pixie Campbell Memorial Keynote The 2014 CIC took place September 10–12 at the Beaver Address at the CIC Run Resort and Conference Center in Breckenridge, Colorado. The conference, organized, in part, by Laurel Lenz (AAI ’05), drew 167 attendees and covered a diverse array of topics, from gut microbiota to alphaviruses. AAI sponsored the Pixie Campbell Memorial Keynote Address, delivered by Diane Griffin (AAI ’75), who spoke on “Viral disease and the immune response.” In addition, AAI provided funding for eight Young Investigator Awards at the CIC. Four oral presentation awards were given to Kira Rubtsova (National Jewish Health), Rochelle Hinman (University of Colorado), Seth Welsh (National Jewish Health and University of Colorado), and Robin Lindsay (National Jewish Health Above: AAI Young Investigator and University of Colorado). Recipients of the four awardee Mira Estin at the CIC poster presentation awards that were also given were Sarah Clark, Daniel McDermott, and Janie Akerlund Left: AAI Young Investigator awardee Robin Lindsay (right) (University of Colorado) and Mira Estin (National Jewish discussing his work with another Health and University of Colorado). conference attendee

Northern Immunological Mountain Society Annual Meeting (NIMS)

Fifty-three scientists traveled to Bolton Valley, Vermont, to attend the NIMS, held September 12–14. The meeting, organized by Karen Fortner (AAI ’07), Mercedes Rincon (AAI ’03), and Ralph Budd (AAI ’90), focused on providing trainees with NIMS trainee attendees posing between scientific sessions opportunities to present their work orally. The program featured creatively AAI sponsored registration for 23 graduate titled sessions, including “Death by sugar; surviving off students and postdoctoral fellows at the NIMS. the fat,” which highlighted the relationship between The recipients were Matthew Alexander, Megan metabolism and immunity, and “Bugs I: the little guys,” O’Connor, Jessica Rastad, and Iviana Torres which focused on viral immunity. Stephen Hedrick (AAI (Dartmouth Medical College); Kelly Hawley, Ishita ’81) delivered the keynote address, entitled “Immune Banerjee, Sara Colpitts, Juliette Mouries, Sara Memory: A Human Construct with an Ancient Paveglio, Oriana Perez, Pablo Romagnoli, and Sierra Biological Past.”

18 AAI Newsletter Winter 2014-2015 Root (University of Connecticut); Bianca Bautista and Allen Vong (University of Massachusetts); Delphine Planas and Tévy-Suzy Tep (Université de Montréal-CRCHUM); and Edward Burgess, Victoria DeVault, Dimitry Krementsov, Michael Secinaro, Tina Thornton, Phyu Thwe, and Rui Yang (University of Vermont).

La Jolla Immunology Conference (LJIC) Left: (l-r) LJIC organizers Ananda Goldrath, Klaus The Salk Institute hosted 375 attendees for the LJIC, which Ley, and Catherine took place September 30–October 2 in La Jolla, California. Hedrick with Björn Lillemeier The meeting was organized, in part, by Klaus Ley (AAI ’00), Ananda Goldrath (AAI ’05), and Catherine Hedrick (AAI ’10) and included sessions ranging from lymphocyte development to host-pathogen interactions. Jason Cyster (AAI ’97) delivered the keynote address, speaking on “Deciphering the guidance cue code for B cell immunity.” AAI sponsored 10 Young Investigator Awards at the LJIC—five oral and five poster presentations. The oral presentation awardees were Anthony Phan and Claudia Bossen (University of California, San Diego), Sara McArdle and Shilpi Verma (La Jolla Institute for Allergy and Immunology), and Shivashankar Othy (University of California, Irvine). The poster presentation awards were given to Tyler Landtrith (University of California,

Riverside), Laura Shaw (University of California, San AAI President Linda Sherman (far right) posing with LJIC AAI Young Diego), Tobias Dong (University of California, Irvine), Investigator awardees and conference organizers Klaus Ley (second from Florent Carrette (Sanford Burnham Research Institute), right), Ananda Goldrath (front row, far left), and Catherine Hedrick (back row, second from left) and Darina Spasova (La Jolla Institute for Allergy and Immunology).

New York Immunology Conference (NYIC) Over 100 scientists attended the NYIC, held October 19–22 at the Sagamore Resort and Conference Center in Bolton Landing, New York. James Drake (AAI ’01) and Katherine Macnamara (AAI ’11) organized the proceedings, which highlighted keynote lectures by Arturo Casadevall (AAI ’98) and Michael Cancro (AAI ’79) and featured oral presentations by trainee scientists. The organizing committee selected 10 trainees to receive AAI Young Investigator Awards and present oral abstracts during the conference sessions. The awardees were Jocelyn Wang, Erika Gruber, and Norah Smith (Cornell University); Megan O’Connor (Dartmouth NYIC AAI Young Investigator awardees pausing for a photo break during the University); Jie Yang and Kristin Fino (Pennsylvania State busy conference schedule University); Adam Utley (Roswell Park Cancer Institute); Cody Spencer (Trudeau Institute); and Lisbeth Boule and Aditi Murthy (University of Rochester).

18 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 19 The AAI Grant Review for Immunologists Program Invites New Participants as It Marks a Major Milestone

or more than one decade, the AAI Grant experience,” remarked Annette Khaled FReview for Immunologists Program (AAI ’03). “My mentor emphasized the (GRIP) has offered young principal importance of writing your specific aims investigators (PIs) the opportunity to page first and told me if I could get this one consult established scientists for advice on component right, the rest of the grant would how to write an effective grant proposal. The flow out organically from there. I had never program was launched and sustained under thought of grants that way before. We spent the skillful direction of Andy Hurwitz (AAI two to three weeks conversing only about ’99) from its inception in 2002 until this fall this page. Learning that single point from when Steve Varga (AAI ’03) assumed the post him was sufficient to change the way I write of program coordinator. grants and has been instrumental to my Andy Hurwitz The program coordinator, together with a success in obtaining funding.” Jim Song (AAI cadre of senior PIs, matches early career PIs ’03) noted that his mentor gave him very with mentors in their area of expertise who detailed feedback that helped him receive can offer guidance on grant-writing skills a better score upon resubmission, saying, and navigation of the NIH review process. “I was having problems with describing an approach in one of my specific aims, so my Impetus for founding the program, mentor provided me with suggestions for according to Hurwitz, was the fact that improving this section. When I resubmitted some investigators do not receive adequate the grant, it received a better score than it training in grant writing during their had previously.” predoctoral and postdoctoral training experiences, leaving many ill-equipped Scott Abrams (AAI ’96) was adamant in his to write a compelling grant proposal as belief that mentorship from an established investigator was critical to writing an effective they begin their faculty careers. Over the Steve Varga years, GRIP mentors have addressed a range grant application, saying, “There are aspects of of “grantsmanship” issues, including some as basic as grantsmanship—intangibles—that can only be identifying an appropriate strategy for responding to learned by communicating with a scientist who has ample reviewer critiques in a resubmitted grant application or experience with the study section review process and has the importance of adapting one’s writing style for the NIH successfully and regularly obtained funding. My mentor grant application. “Young PIs often don’t understand that offered me insight into the best way to illustrate my ideas, a grant application is different from the other forms of which is something you may not think about prior to going writing that scientists do—papers and reviews. The grant through the experience.” application is an advertisement. You’re trying to sell your GRIP mentees may reap additional benefits beyond the project to reviewers,” says Suzanne Ostrand-Rosenberg development of grantsmanship skills. Ostrand-Rosenberg (AAI ’79). “Young PIs tend to think that by throwing their elaborates, stating, “A GRIP mentor can be an avenue that science up for all to see, the reviewers will just appreciate connects junior investigators with other senior investigators it and fund the proposal, but that’s not how it works. A in their field of expertise. It improves the exposure of the grant has to be properly packaged and presented to grab junior person and facilitates networking.” Goverman cites the attention of the reviewer.” additional benefits, saying, “It’s possible that reagents might Another GRIP advisor, Joan Goverman (AAI ’95), be exchanged in the future or new collaborations could agrees that presentation and packaging skills are areas develop. The program has the potential to open a lot of that the GRIP volunteers frequently address. “You doors for a young investigator.” bring your idea and you bring your proposal of how to accomplish that idea. You need to concisely state those The GRIP Process things along with clear specific aims in the first page, or you’ll lose the reader and your grant is unlikely to be Early career PIs wishing to be matched with a GRIP funded,” she cautions. mentor may submit their CVs along with the specific- aims page of their R01 or R15 grant proposal. The Past GRIP participants attest to the benefits of the applications are screened by GRIP Coordinator Steve program, noting how their grant-writing skills evolved Varga and referred to the GRIP volunteers to be matched during the GRIP process. “It was an eye-opening with an expert in the applicant’s area of expertise.

20 AAI Newsletter Winter 2014-2015 Applicants should apply at least eight weeks ahead New Applicants and Advisors Welcome of the grant deadline to allow ample time for the match AAI invites both prospective GRIP mentees and mentors to process and for mentors to review the grants. Varga inquire about GRIP at [email protected]. emphasized the importance of submitting proposals to GRIP well ahead of the NIH grant deadline, stating, Early career PIs interested in participating in GRIP may “Not only does it allow time for the mentor to review submit their CVs and the specific-aims page of their grant the grant, but it allows time for the applicant to take proposals to the above email address, referencing “GRIP” in those critiques and revise the application…and maybe the email subject line. go through a second round with the mentor. That [the Senior investigators wishing to be considered as potential second round] is where the learning process occurs and advisors for the program should email their CVs and an where the value of the program really lies.” outline of their grant-reviewing experience also to infoaai@ The mentor and mentee interact via email and/or aai.org, again referring to GRIP in the subject line. phone to discuss the grant proposal. Advisors usually For more information about GRIP, please visit spend between 8 and 16 total hours reviewing each aai.org/Education/GRIP. mentee’s grant proposal, but some mentors reported spending several months interacting with their mentees AAI gratefully acknowledges the service of the AAI GRIP and reviewing up to four iterations of the grant. Subcommittee. Varga is eager to raise awareness of the program and Steven Varga, Chair James Sheil ensure its continued success, saying, “My main goal is University of Iowa West Virginia University to improve the visibility of the program and make sure Rachel Gerstein School of Medicine AAI members, particularly new investigators, are aware University of Laurie Harrington of the opportunities GRIP presents. It’s a great program Massachusetts Medical University of Alabama at that has the potential to provide grant review support School Birmingham to members who may not have mentorship within their specialty at their own institutions.” Laurence Morel Andy Hurwitz University of Florida National Cancer Institute John Schreiber Tufts Medical Center

Get a GRIP: An AAI program designed to help new investigators prepare their NIH grant proposals The AAI Grant Review for Immunologists Program (GRIP) offers new principal investigators (PIs) access to established PIs for guidance in preparing grant proposals as they embark on their independent careers. Early-career PIs (assistant professors or equivalents) are invited to submit their grants’ “Specific Aims” pages to the GRIP coordinator who, with the assistance of a small volunteer subcommittee, will attempt to match each topic of the proposal with the research experience of an established PI. Matches will be made as quickly as possible to allow participants to meet upcoming NIH grant deadlines. Participation is open only to AAI regular members and is strictly voluntary. The program is not intended to supplant internal mentoring programs at applicants’ institutions. To apply, please send your CV and the grant’s “Specific Aims” page to [email protected]. (please write “GRIP” in the subject line) To volunteer as a mentor, please send your CV and a brief description of your grant-reviewing experience to [email protected]. (subject line “GRIP”) Program details at aai.org/Education/GRIP

20 AAI Newsletter Winter 2014-2015 www.aai.orgAAI_GripAd_1-2Pg.2014.indd 1 AAI Newsletter11/4/14 5:39 PM21 High School Teachers in AAI Summer Research Program Present Model Curricula at NABT Conference

Program—Immunology Lessons for the Classroom,” are listed with their mentors and talk titles below: Control of the allergic response Catherine Dollard, Northampton High School, Northampton, Massachusetts Mentor: Clinton B. Mathias, AAI ’10, Western New England Special Discounts University Director Clinton Mathias (left) and Educational Consultant Megean Garvin (right) Chronic inflammation: causes and consequences with 2014–15 AAI High School Teachers participants (l-r) Edwina Kinchington, Amy for AAI Member Authors Loewen, Lori Fretta, Catherine Dollard, Beth Krauss, and John Siefert (missing: Lori Fretta, Otter Valley Union High School, Brandon, Vermont Kindra Zuberbuehler) Mentor: Karen A. Fortner, AAI ’07, University of Vermont College of Medicine articipants in the 2014–15 AAI High School Teachers Using immunology to understand cell growth, protein structure, Waiver of Manuscript Submission Fee PSummer Research Program in Immunology gathered at the and specificity National Association of Biology Teachers (NABT) Professional Edwina C. Kinchington, Pittsburgh Public Schools, Pittsburgh, Development Conference, November 12–15 in Cleveland, Pennsylvania Corresponding authors who are regular, associate, emeritus, or honorary AAI members in Ohio. AAI arranged for the seven teachers to be invited there to Mentor: Christine Milcarek, AAI ’85, University of Pittsburgh good standing on the date of manuscript submission to The Journal of Immunology receive showcase curricula that they had developed from participating School of Medicine in the AAI program for high school science teachers to learn a waiver of the $50 submission fee. Using Lyme disease to teach immunological principles how to bring immunology lessons into their classrooms. Beth R. Krauss, Manlius Pebble Hill School, DeWitt, New York The teachers’ presentations at the NABT were an important Mentor: Gary Winslow, AAI ’96, Upstate Medical University milestone of their year in the AAI program. In the AAI program, Teaching the basics of immunology through clinical case teachers are provided four- to six-week summer research studies and assays Reduced Charges experiences in the laboratories of AAI members. Before starting Amy Loewen, Hinkley High School, Aurora, Colorado in the laboratory, the teachers are given an opportunity to for Color Figures Mentor: Ronald J. Harbeck, AAI ’78, National Jewish Health attend the AAI Introductory Course in Immunology, held this Advanced Diagnostic Labs year in July at the Long Beach Convention Center. Following the Corresponding authors who are regular, associate, emeritus, teachers’ mentored lab experiences, an educational consultant Exploring the immune response and autoimmunity through assists them with the development of innovative curricula systemic lupus erythematosus or honorary AAI members in good standing on the date their manuscript is accepted based on their summer projects for use in their own classrooms. John Siefert, Conrad Weiser Area School District, Robesonia, for publication in The Journal of Immunology receive a $300 reduction in the cost of each Finally, the teachers are given an opportunity to share their Pennsylvania color gure. projects at a national meeting. To reach a broader audience of Mentor: Angelika Antoni, AAI ’13, Kutztown University high school science teachers, AAI elected this year to support A study of light & fluorescence in the instruments of the AAI program’s teacher participation at the NABT rather immunologists . . . . than at the AAI annual meeting. “Most often the AAI program Kindra M. Zuberbuehler, Wake County Public School System, participants have presented their posters and their talks at Apex, North Carolina For complete details on AAI membership privileges and bene ts, eligibility requirements, the AAI annual meeting, and local high school teachers and Mentor: Richard Lee Reinhardt, AAI ’11, Duke University and application forms, please visit www.aai.org/membership, contact the AAI membership students are invited to attend. The NABT venue, however, was Medical Center optimal for enabling the teachers to present their immunology o ce at 301-634-7195, or email [email protected]. classroom exercises to an audience of fellow science teachers The session spanned many immunological topics, from around the United States,” said AAI Manager of from allergy and inflammation to autoimmunity and Educational and Career Development Programs Mary Litzinger. instrumentation. It also spanned different presentation styles. For complete details on manuscript submission to The JI, please visit www.jimmunol.org, Zuberbuehler shared her presentation via a YouTube link contact The JI o ce at 301-634-7197, or email [email protected]. Clinton B. Mathias (AAI ’10), assistant professor at Western when inclement weather and associated delays prevented her New England University and director of the AAI High School from making the session. The session ended with Dollard’s Teachers Program, said, “It was inspiring to see the creative presentation, in which she recruited her fellow teachers to help ways in which the teachers adapted their immunology with a dramatization of the immune response. laboratory experiences to their classrooms. We hope that this program assists high school teachers nationwide in bringing Members are urged to consider nominating a talented high the excitement of immunology research to the classroom and school teacher for the 2015 summer program. The AAI model helping to cultivate the next generation of investigators.” curricula are archived and made publicly available on the AAI website. To view their immunology lessons and learn more Teachers participating in the 2014–15 AAI program and the about this program, visit www.aai.org/Education/Summer_ NABT session, “AAI Presents: High School Teachers Research Teachers/. 22 AAI Newsletter Winter 2014-2015 Special Discounts for AAI Member Authors

Waiver of Manuscript Submission Fee

Corresponding authors who are regular, associate, emeritus, or honorary AAI members in good standing on the date of manuscript submission to The Journal of Immunology receive a waiver of the $50 submission fee.

Reduced Charges for Color Figures

Corresponding authors who are regular, associate, emeritus, or honorary AAI members in good standing on the date their manuscript is accepted for publication in The Journal of Immunology receive a $300 reduction in the cost of each color gure. . . . . For complete details on AAI membership privileges and bene ts, eligibility requirements, and application forms, please visit www.aai.org/membership, contact the AAI membership o ce at 301-634-7195, or email [email protected].

For complete details on manuscript submission to The JI, please visit www.jimmunol.org, contact The JI o ce at 301-634-7197, or email [email protected].

22 AAI Newsletter Winter 2014-2015 GRANT AND AWARD DEADLINES

February 2 January 12 Amgen Scholars (U.S. Program; Europe AAI Travel Awards and Grants (see also Program; Japan Program) Call for 2015 Applications, p. 5) n Prize/Award: Support for undergraduates to participate in cutting-edge research opportunities at n Prize/Award: Awards in 11 categories one of 17 leading institutions of higher learning in the recognizing the promise and bolstering the United States, Europe, and Japan; scholars undertake a professional development of investigators of all summer research project under top faculty, participate career stages through support for travel to the with peers in seminars and networking events, and AAI annual meeting take part in a regional symposium led by leading n Eligibility: Subject to limited exceptions, biotechnology scientists from industry and academia eligibility extends to AAI members in good n Eligibility: U.S. Program—U.S. citizens or permanent standing residents who are undergraduate students enrolled in n Details: www.aai.org/awards accredited four-year colleges or universities in the U.S., n Contact: AAI: (301) 634-7178; [email protected] Puerto Rico, or other U.S. territories, have a cumulative grade point average of 3.2 or above, and are interested in pursuing a Ph.D. or M.D.-Ph.D.; Europe Program— open to students in Europe; Japan Program—open to students worldwide n Details: http://amgenscholars.com/us-program January 28 n Contact: U.S. Program Office: (617) 253-2620; AAI Public Policy Fellows Program [email protected]; Europe/Japan Programs: http://amgenscholars.com/contact (PPFP) n Prize/Award: Awards in 11 categories recognizing the promise and bolstering the February 2 professional development of investigators of all Lasker Awards in Basic and career stages through support for travel to the Clinical Medical Research AAI annual meeting n Prize/Award: Separate awards each conferring an n Eligibility: Subject to limited exceptions, honorarium of $250,000 in recognition of a scientist eligibility extends to AAI members in good or scientists whose fundamental investigations standing have provided techniques, information, or concepts n Details: www.aai.org/awards contributing to the elimination of major causes of disability and death (Albert Lasker Basic Medical Research n Contact: AAI: (301) 634-7178; [email protected] Award) and improved the clinical treatment of patients (Lasker-DeBakey Clinical Medical Research Award) n Eligibility: Scientists and/or physicians who are nominated by a colleague and have made major advances in the understanding, diagnosis, treatment, cure, and prevention of human disease and/or whose work opens new areas of biomedical science n Details: http://www.laskerfoundation.org/nominate.htm n Contact: David Keegan: (212) 286-0222; dkeegan@ laskerfoundation.org

24 AAI Newsletter Winter 2014-2015 February 4 American Asthma Foundation (AAF) February 16 Scholar Awards AAI Travel for Techniques Awards n Prize/Award: Multiple awards, each of up to (see also Call for Winter 2014-2015 $150,000 annually for two years, in support Applications, p. 2) of innovative research with the potential to n Prize/Award: Up to $1,500 in reimbursable impact asthma, including research proposed by expenses to support travel to another laboratory investigators currently working outside the asthma to learn a particular technique relevant to the field; awards may be extended to a third year based applicant’s research but inaccessible at local on progress and potential institutions n Eligibility: Early- and mid-career investigators of n Eligibility: Qualifying AAI regular and associate any nationality and citizenship who are working members in good standing seeking to expand in the U.S., have held their first independent their skills to benefit their research faculty appointment for not more than 10 years, and have an independent research program with n Details: www.aai.org/awards national-level, independent funding; the program n Contact: AAI: (301) 634-7178; [email protected] is predicated on offering scientists the freedom to pursue new ideas without requiring preliminary data n Details: http://www.americanasthmafoundation.org/ n Contact: Valerie Dougherty, Program Manager: (415) 514-0730; [email protected] March 16 AAI Careers in Immunology Fellowship February 10 (see also Call for 2015 Nominations, p. 2) Young Investigator Grant for Probiotics n Prize/Award: Multiple awards in support Research of the laboratories of AAI member principal investigators (PIs), each providing one year’s n Prize/Award: Three $50,000 research grants in salary for a graduate student or postdoctoral support of new, exploratory research on probiotics fellow working in the PI’s lab and gastrointestinal microbiota in the United States n Eligibility: AAI member principal investigators n Eligibility: Young investigators committed to with less than $250,000 (excluding PI’s salary) basic research on gastrointestinal microbiota, in annual direct costs probiotics, and their role in health and wellness, including those who do not yet have independent n Details: http://www.aai.org/Awards/ funding; senior fellows with a committed faculty Fellowship.html appointment or early faculty members within n Contact: [email protected] a maximum of 5 years of their first faculty appointment (must be in the United States) may apply; proposed research must be conducted at non-profit, U.S. institutions with research programs demonstrating the capacity for probiotics research n Details: www.probioticsresearch n Contact: [email protected]

24 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 25 Welcome to all new AAI Members! Your membership in AAI benefits you, your area of research, your member colleagues, and the field.

AAI Welcomes New Members (2014)

AAI is very pleased to welcome all new members for the 2014 membership year.

Listed below are the 465 new regular and associate members who were added in 2014. Also added in 2014 were 839 new trainee members. To view the list online, go New members listed to: www.aai.org/Membership/newmemberlist.pdf. below appear in alphabetical order by state (U.S.) Please personally welcome the new members you know and make a point of and country (International). introducing yourself to those near you whom you haven’t met.

REGULAR Wenxian Fu, Ph.D. Nisebita Sahu, Ph.D. Claudia Jakubzick, Ph.D. Richard Louis Riley, Ph.D. United States La Jolla, CA South San Francisco, CA Denver, CO Davie, FL Alabama Amanda L. Gavin, Ph.D. William Schief, Ph.D. Stephanie James, Ph.D. Mark S. Sundrud, Ph.D. La Jolla, CA La Jolla, CA Denver, CO Jupiter, FL Tara M. DeSilva, Ph.D. Birmingham, AL Andrew Whitman Goodyear, John R. Sedy, Ph.D. Edward N. Janoff, M.D. Georgia Ph.D. La Jolla, CA Aurora, CO Srilalitha Kuruganti, Ph.D. San Bruno, CA Jianxu Li, Ph.D. Birmingham, AL Iftach Shaked, Ph.D. Eoin N. McNamee, Ph.D. Decatur, GA Iris K. Gratz, Ph.D. La Jolla, CA Aurora, CO Qiana Latrese Matthews, Ph.D. San Francisco, CA Feng Liu, M.D., Ph.D. Birmingham, AL Srividya Swaminathan, Ph.D. Connecticut Atlanta, GA Bethany Michele Henrick, San Francisco, CA Mark R. Walter, Ph.D. Ph.D. Martin S. Kluger, Ph.D. Santhakumar Manicassamy, Jonathan Tam, M.D. Birmingham, AL Elk Grove, CA New Haven, CT Ph.D. Los Angeles, CA Augusta, GA Alaska Zhongdong John Huang, Ph.D. Martin A. Kriegel, M.D., Ph.D. Xiaolei Tang, M.D., Ph.D. San Diego, CA New Haven, CT Mirko Paiardini, Ph.D. Brenna Simons, Ph.D. Loma Linda, CA Atlanta, GA Anchorage, AK Charles D. Kaplan, Ph.D. Thomas D. Manes, Ph.D. Isela C. Valera, Ph.D. South San Francsico, CA New Haven, CT Lisa M. Shollenberger, Ph.D. Arizona Los Angeles, CA Atlanta, GA Elad H. Kaufman, Ph.D. Adam Matson, M.D. H. Christian von Bådingen, M.D. Dominik Schenten, Ph.D. South San Francisco, CA Farmington, CT Iowa Pine Bluff, AR San Francisco, CA Suneil K. Koliwad, M.D., Ph.D. Vijay Rathinam, D.V.M., Ph.D. Abigail L. Henderson, Ph.D. Zhong Wang, Ph.D. Arkansas San Francisco, CA Farmington, CT Ankeny, IA Foster City, CA A. Selma Dagtas, M.D., Ph.D. Richard S. Kornbluth, M.D., Lauren H. Sansing, M.D. Holly R. Hughes, Ph.D. Pine Bluff, AR Daniela Weiskopf, Ph.D. Ph.D. Farmington, CT Ames, IA La Jolla, CA V. Laxmi Yeruva, Ph.D. La Jolla, CA Brian S. Sheridan, Ph.D. Scott M. Lieberman, M.D., Ph.D. Little Rock, AR Ian A. Wilson, D.Sc., Ph.D. Cecilia S. Lindestam Arlehamn, Farmington, CT Iowa City, IA La Jolla, CA California Ph.D. Yun-Hee Youm, Ph.D. William M. Nauseef, M.D. La Jolla, CA Changchun Xiao, Ph.D. New Haven, CT Coralville, IA Iannis Adamopoulos, Ph.D. La Jolla, CA Sacramento, CA Andrea I. Loewendorf-Snead, Florida Yatin M. Vyas, M.D. Ph.D. Alice L. Yu, M.D., Ph.D. Iowa City, IA Marion S. Buckwalter, M.D., Los Angeles, CA San Diego, CA Marisela D. Agudelo, Ph.D. Ph.D. Miami, FL Illinois Stanford, CA Gerrit Los, Ph.D. Isharat Yusuf, Ph.D. South San Francisco, CA San Diego, CA Alexey Y. Berezhnoy, D.V.M., John Patrick Galvin, Jr., M.D., Swey-Shen Alex Chen, D.Sc. Ph.D. M.P.H. San Diego, CA Henriette Macmillan, Ph.D. Traci Zell, Ph.D. Miami, FL Chicago, IL San Francisco, CA San Diego, CA Thomas C. Chen, M.D. Larry J. Dishaw, Ph.D. Justin Kline, M.D. La Canada, CA Rajkumar Noubade, Ph.D. Colorado St. Petersburg, FL Chicago, IL San Carlos, CA Troy D. Cline, Ph.D. Rachel Sharon Friedman, Ph.D. Shuhong Han, Ph.D. Joseph Ross Leventhal, M.D., Chico, CA Pedro E. Paz, Ph.D. Denver, CO Gainesville, FL Ph.D. San Francisco, CA Isaac Engel, Ph.D. Bridget Gordon, Ph.D. Gustavo J. Martinez, Ph.D. Chicago, IL La Jolla, CA Mepur H. Ravindranath, Ph.D. Boulder, CO Jupiter, FL Salvador Nares, D.D.S., Ph.D. Los Angeles, CA Aaron Palmer Esser-Kahn, Ph.D. Chunjian Huang, Ph.D. Corwin D. Nelson, Ph.D. Chicago, IL Irvine, CA William H. Robinson, M.D., Denver, CO Gainesville, FL David Perkins, M.D., Ph.D. Ph.D. Chicago, IL Donald Forthal, M.D. Stanford, CA Jennifer L. Owen, D.V.M., Ph.D. Irvine, CA Ocala, FL

26 AAI Newsletter Winter 2014-2015 Melody A. Swartz, Ph.D. Jung-Hyun Park, Ph.D. Adam Lerner, M.D. Pirooz Eghtesady, M.D., Ph.D. Morgan Huse, Ph.D. Chicago, IL Bethesda, MD Boston, MA St. Louis, MO New York, NY Julie A. Swartzendruber, Alexander V. Pichugin, M.D., Adam G. Matthews, Ph.D. Grzegorz Bogdan Gmyrek, Young-Min Hyun, Ph.D. Ph.D. Ph.D. Wellesley, MA D.O., Ph.D. Rochester, NY Chicago, IL Silver Spring, MD St. Louis, MO Gerd Meyer zu Horste, M.D. Mithilesh K. Jha, Ph.D. Edward B. Thorp, Ph.D. Nicholas P. Restifo, M.D. Boston, MA Kristin L. Griffiths, Ph.D. Saranac Lake, NY Chicago, IL Bethesda, MD St. Louis, MO Kerstin (Kiefer) Nundel, Ph.D. Warren V. Kalina, Ph.D. Carl Waltenbaugh, Ph.D. Meiqing Shi, Ph.D. Worcester, MA Yong Miao, Ph.D. Tarrytown, NY Chicago, IL College Park, MD St. Louis, MO Christine D. Palmer, Ph.D. Julia Kaufman, Ph.D. Andrew Zloza, M.D., Ph.D. Yuhong Shi, M.D., Ph.D. Cambridge, MA Edward J. Pearce, Ph.D. Tuckahoe, NY Chicago, IL Baltimore, MD St. Louis, MO Ravisankar Ramadas, D.V.M., Sergei B. Koralov, Ph.D. Indiana Nevil J. Singh, Ph.D. Ph.D. Emma Teixeiro, Ph.D. New York, NY Baltimore, MD Boston, MA Columbia, MO Keke C. Fairfax, Ph.D. Jill M. Kramer, D.D.S., Ph.D. West Lafayette, IN Andrew L. Snow, Ph.D. Namita Rout, Ph.D. Caihong Wang, Ph.D. Buffalo, NY Bethesda, MD Southborough, MA St. Louis, MO Samantha Nichole Oliphant, P’ng Loke, Ph.D. Ph.D. Greg A. Snyder, Ph.D. Carol E. Schrader, Ph.D. Montana New York, NY Baltimore, MD Worcester, MA Indianapolis, IN Diane Bimczok, D.V.M., Ph.D. Sridhar Mani, M.D. Kristin Tarbell, Ph.D. Seng-Lai Tan, Ph.D. Bozeman, MT Bronx, NY Kansas Bethesda, MD Billerica, MA Nebraska Phyllis M. O’Donnell, Ph.D. Yongming Sang, Ph.D., Sc.D. Rebekah Taylor, Ph.D. Catherine T. Yan, Ph.D. Endicott, NY Manhattan, KS Frostburg, MD Boston, MA Santhi Gorantla, Ph.D. Omaha, NE Jennifer A. Philips, M.D., Louisiana Rajat Varma, Ph.D. Kei Yasuda, Ph.D. Ph.D. Qingsheng Li, Ph.D. Jacob P. Bitoun, Ph.D. Bethesda, MD Boston, MA New York, NY Lincoln, NE New Orleans, LA Elizabeth Walsh, Ph.D. Michigan Xia Qian, M.D., Ph.D. Samuel J. Landry, Ph.D. Bethesda, MD New Hampshire Bronx, NY Nardhy Gomez-Lopez, Ph.D. New Orleans, LA Richard P. Weitzel, Ph.D. Detroit, MI David A. Blair, Ph.D. Brian D. Rudd, M.P.H., Ph.D. Mahesh Mohan, D.V.M., Ph.D. Bethesda, MD Lebanon, NH Ithaca, NY Fumito Ito, M.D., Ph.D. Covington, LA Wathsala K. Wijayalath, Ph.D. Ann Arbor, MI Mark S. de Souza, M.P.H., Stuart C. Sealfon, M.D. Silver Spring, MD Ph.D. New York, NY Maryland Jennifer Jean Linderman, Nashua, NH Joy Williams, Ph.D. Ph.D. Sharon A. Singh, M.D. Jobert G. Barin, Ph.D. Bethesda, MD Manhasset, NY Baltimore, MD Ann Arbor, MI New Jersey Xiaoyu Zhang, Ph.D. Selin Somersan Karakaya, Chew Shun Chang, Ph.D. Carey N. Lumeng, M.D., Ph.D. Ian Catlett, Ph.D. Baltimore, MD Ann Arbor, MI Princeton, NJ M.D. Gaithersburg, MD New York, NY Michael A. Chattergoon, M.D., Massachusetts Sumanta Mukherjee, Ph.D. Maria L. Gennaro, M.D. Ann Arbor, MI Newark, NJ Joel N. H. Stern, Ph.D. Ph.D. Faith D. Bahunde, Ph.D. Hempstead, NY Baltimore, MD Milford, MA Matthew Schaller, Ph.D. New Mexico Ann Arbor, MI Yasmin M. Thanavala, Ph.D. Sidhartha Chaudhury, Ph.D. Xinming Cai, Ph.D. Aaron Kurt Neumann, Ph.D. Buffalo, NY Frederick, MD Cambridge, MA Albuquerque, NM Minnesota Ivana Vancurova, Ph.D. Malarvizhi Durai, Ph.D. Aaron Castro, Ph.D. Mary A. Antonysamy, Ph.D. Queens, NY Ellicott City, MD Acton, MA New York Woodbury, MN Jayanta Chaudhuri, Ph.D. Ping Wang, M.D. Jeffy George, Ph.D. Wei Chao, M.D., Ph.D. Santanu Banerjee, Ph.D. New York, NY Manhasset, NY Gaithersburg, MD Boston, MA Minneapolis, MN Drew Cressman, Ph.D. Jingxiu Xuan, M.D., Ph.D. William G. Hearl, Ph.D. Janet S. Chou, M.D. Sarah Cooley, M.D., M.P.H. Bronxville, NY Buffalo, NY Rockville, MD Boston, MA Minneapolis, MN Kevin Anthony Da Silva, Ph.D. Alexandra Zanin-Zhorov, Shawn S. Jackson, Ph.D. Michael J. Elliott, M.B.B.S., Richard B. Kennedy, Ph.D. New York, NY Ph.D. Takoma Park, MD Ph.D. Rochester, MN New York, NY Cambridge, MA Tetyana L. Delaney, Ph.D. Christopher M. Jewell, Ph.D. Scott W. McPherson, Ph.D. Brooklyn, NY College Park, MD Wassim Elyaman, Ph.D. North Carolina Minneapolis, MN Boston, MA Marcella M. Flores, M.P.H., Melinda A. Beck, Ph.D. Brian L. Kelsall, M.D. Erik J. Peterson, M.D. Ph.D. Chapel Hill, NC Bethesda, MD Jordan Barry Fishman, Ph.D. Minneapolis, MN Brooklyn, NY Marlborough, MA Mulugu V. Brahmajothi, Ph.D. Stephane Lajoie, Ph.D. Regan C. Pyle, D.O. David R. Fooksman, D.O., Durham, NC Baltimore, MD David J. Gregory, Ph.D. Rochester, MN Ph.D. Boston, MA Gianna Hammer, Ph.D. Jianqing Li, Ph.D. Bronx, NY Debby Walser-Kuntz, Ph.D. Durham, NC Gaithersburg, MD Kambez Hajipouran Benam, Northfield, MN Adolfo Garcia-Sastre, Ph.D. Ph.D. Nancie J. MacIver, M.D., Ph.D. Susan Moir, Ph.D. New York, NY Boston, MA Missouri Durham, NC Bethesda, MD Alan Hanash, M.D., Ph.D. Erin M. Janssen, M.D., Ph.D. Maxim Artyomov, Ph.D. New York, NY Zachariah A. McIver, D.O. Boston, MA St. Louis, MO Winston-Salem, NC

26 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 27 Welcome to all new AAI Members (continued)

Luis A. Sanchez-Perez, Ph.D. Ann Jones Hessell, Ph.D. Ekaterina Koltsova, M.D., South Dakota Junmei Wang, Ph.D. Durham, NC Beaverton, OR Ph.D. Richard M. Rembecki, M.D., Houston, TX Philadelphia, PA Lauren V. Schnabel, D.V.M., Evan F. Lind, Ph.D. Ph.D. Jinsheng Weng, M.D., Ph.D. Ph.D. Portland, OR Michele A. Kutzler, Ph.D. Sioux Falls, SD Houston, TX Raleigh, NC Philadelphia, PA Jeffrey C. Nolz, Ph.D. Tennessee Zhenming Xu, Ph.D. Laura Watts, Ph.D. Portland, OR Courtney Marcia Lappas, San Antonio, TX Pradyot Dash, D.V.M., Ph.D. Winston Salem, NC Ph.D. Holly L. Rosenzweig, Ph.D. Memphis, TN Annville, PA Utah Haitao Wen, Ph.D. Portland, OR Alyssa Hasty, Ph.D. Chapel Hill, NC Shuguang Li, M.B.B.S., Ph.D. Dean Li, M.D., Ph.D. Nashville, TN Pennsylvania Willow Grove, PA Salt Lake City, UT Xiaojing Zheng, M.D., Ph.D. Simon Alexander Mallal, Chapel Hill, NC John F. Alcorn, Ph.D. John D. Lich, Ph.D. M.B.B.S. Vermont Pittsburgh, PA Collegeville, PA North Dakota Nashville, TN Eyal Amiel, Ph.D. Rajesh K. Aneja, M.D. Robbie B. Mailliard, Ph.D. Burlington, VT Gregor Neuert, Ph.D. Suba Nookala, Ph.D. Pittsburgh, PA Pittsburgh, PA Grand Forks, ND Nashville, TN Virginia Pierette M. Appasamy, Ph.D. Joshua T. Mattila, Ph.D. Danyvid Olivares-Villagomez, Ohio Pittsburgh, PA Pittsburgh, PA Kristian Michael Hargadon, Ph.D. Ulf H. Beier, M.D. Ph.D. Enguang Bi, Ph.D. Laura M. McLane, Ph.D. Nashville, TN Hampden-Sydney, VA Cleveland, OH Philadelphia, PA Philadelphia, PA Elizabeth J. Phillips, M.D. Scott B. Berger, Ph.D. Eun D. Lee, Ph.D. Arlene Dent, M.D., Ph.D. Matthew L. Nicotra, Ph.D. Nashville, TN Richmond, VA Cleveland, OH Collegeville, PA Pittsburgh, PA John V. Williams, M.D. Jennifer M. Boardman, Ph.D. Kenneth J. Oestreich, Ph.D. Michael L. Freeman, Ph.D. Natasa Obermajer, Ph.D. Brentwood, TN Roanoke, VA Cleveland, OH Scranton, PA Pittsburgh, PA Dahui You, Ph.D. Egidio Brocca Cofano, Ph.D. Y. Michael Shim, M.D. Patricia C. Fulkerson, M.D., Jon D. Piganelli, Ph.D. Memphis, TN Charlottesville, VA Ph.D. Pittsburgh, PA Pittsburgh, PA Cincinnati, OH Craig A. Byersdorfer, M.D., Texas Jamie L. Sturgill, Ph.D. Daniel Ricklin, Ph.D. Richmond, VA Marat Khodoun, Ph.D. Ph.D. Philadelphia, PA Stephen J. Anderson, Ph.D. Cincinnati, OH Pittsburgh, PA The Woodlands, TX Bin Xu, Ph.D. Matthew Randall Rosengart, Blacksburg, VA Min-Ho Kim, Ph.D. Xiaohua Chen, M.D., Ph.D. M.D., M.P.H. Maria Bettini, Ph.D. Kent, OH Pittsburgh, PA Pittsburgh, PA Houston, TX Washington Zhifeng Chen, Ph.D. Matthew L. Bettini, Ph.D. Chong Liu, Ph.D. David Rothstein, M.D. Anthony L. Desbien, Ph.D. West Point, PA Houston, TX Cincinnati, OH Pittsburgh, PA Seattle, WA Thomas Condamine, Ph.D. Lindsay G. Cowell, Ph.D. Satish K. Madala, Ph.D. Adam Eugene Snook, Ph.D. Krystalyn E. Hudson, Ph.D. Philadelphia, PA Dallas, TX Cincinnati, OH Philadelphia, PA Seattle, WA Louise M. D’Cruz, Ph.D. Richard H. Gomer, Ph.D. Halima Moncrieffe, Ph.D. Jason E. Stadanlick, Ph.D. David M. Koelle, M.D. Pittsburgh, PA College Station, TX Cincinnati, OH Fort Washington, PA Seattle, WA Greg M. Delgoffe, Ph.D. Haifa Hamdi, Ph.D. Suman Paul, M.B.B.S., Ph.D. Laura Su, M.D., Ph.D. Chris B. Russell, Ph.D. Pittsburgh, PA The Woodlands, TX Toledo, OH Philadelphia, PA Seattle, WA Ronald J. Fecek, Jr., Ph.D. Patrick Hwu, M.D. Daniel Popkin, M.D., Ph.D. Prithu Sundd, Ph.D. Wisconsin Cleveland, OH Fairchance, PA Pittsburgh, PA Houston, TX Patrizia Fuschiotti, Ph.D. Peter A. Keyel, Ph.D. David T. Evans, Ph.D. Elizabeth P. Schlaudecker, Asako Tajima, M.D., Ph.D. Madison, WI M.D., M.P.H. Pittsburgh, PA Pittsburgh, PA Lubbock, TX Cincinnati, OH Eric Scott Halstead, M.D., Silke Paust, Ph.D. Bruce S. Klein, M.D. Jennifer L. Taylor, Ph.D. Madison, WI Lyn M. Wancket, D.V.M., Ph.D. Ph.D. Pittsburgh, PA Houston, TX Hershey, PA Northwood, OH Armando Rivera, Ph.D. Bernadette C. Taylor, Ph.D. Robert H. Vonderheide, M.D., La Crosse, WI Yuhong Yang, M.D. Rosemary A. Hoffman, Ph.D. Ph.D. Houston, TX Columbus, OH Pittsburgh, PA Philadelphia, PA Roger Sciammas, Ph.D. REGULAR Jacob S. Yount, Ph.D. Weizhou Hou, M.D. Jieru Wang, Ph.D. Houston, TX Wexford, PA International Columbus, OH Pittsburgh, PA Michael U. Shiloh, M.D., Ph.D. Bing Yu, M.D., Ph.D. Jiu Jiang, Ph.D. Karla R. Wiehagen, Ph.D. Dallas, TX Cecile King, Ph.D. Swarthmore, PA Darlinghurst, Australia Stow, OH North Wales, PA Anton M. Sholukh, Ph.D. Anton A. Keskinov, M.D., Ph.D Qin Yang, M.D. San Antonio, TX Kelli P. A. MacDonald, Ph.D. Oklahoma Pittsburgh, PA Brisbane, Australia Pittsburgh, PA Sanjiv Sur, M.D. Lakshmi Tulasi Sunkara, Ph.D. Paul Robert Kinchington, Cecelia C. Yates, D.O., Ph.D. Galveston, TX Andreas Bergthaler, D.V.M. Stillwater, OK Ph.D. Vienna, Austria Pittsburgh, PA Robert S. Svatek, M.D. Pittsburgh, PA Oregon Mingquan Zheng, M.D. San Antonio, TX Alexander M. Dohnal, Ph.D. Girish S. Kirimanjeswara, Vienna, Austria Luiz E. Bermudez, M.D. Pittsburgh, PA Hideki Ueno, M.D., Ph.D. D.V.M., Ph.D. Corvallis, OR Dallas, TX Maria Carmen Visus-Miguel, University Park, PA Benjamin D. Ehst, M.D., Ph.D. Ph.D. Portland, OR Vienna, Austria

28 AAI Newsletter Winter 2014-2015 Luciola S. Barcelos, D.Sc. Qing-Wu Yang, M.B.B.S., M.D., Yukimi Sakoda, M.D., Ph.D. Ya-Jen Chang, Ph.D. Maryland Belo Horizonte, Brazil Ph.D. Ube, Japan Taipei, Taiwan Chong Qing, China Andrew J. Graves, M.S. Marco Aurélio Martins, Ph.D. Shuzo Sato, M.D., Ph.D. Huan-Yuan Chen, Ph.D. Rockville, MD Rio de Janeiro, Brazil Yongan Zhang, Ph.D. Fukushima, Japan Taipei, Taiwan Wuhan, China Dawn M. Henson, M.S. James R. Carlyle, Ph.D. Hajime Takeuchi, Ph.D. Jiann Chu Chen, Ph.D. Rockville, MD Toronto, ON, Canada Wei Zhao, M.D., Ph.D. Sanuki, Japan Keelung, Taiwan Jinan, China Annie Johnson, M.S. Bhargavi Duvvuri, Ph.D. Akane Tanaka, D.V.M., Ph.D. Hock-Liew Eng, M.D. Upper Marlboro, MD Toronto, ON, Canada Ivana Munitic, M.D., Ph.D. Tokyo, Japan Kaohsiung, Taiwan Rijeka, Croatia Massachusetts Li Fu, Ph.D. Hirotake Tsukamoto, Ph.D. Lei Wan, Ph.D. Edmonton, AB, Canada Soren Hansen, Ph.D. Kumamoto, Japan Taichung, Taiwan Sharon K. Germana, M.S. Odense, Denmark Boston, MA Paul J. Payette, Ph.D. Masayuki Umemura, Ph.D. Daniel Henry Paris, M.D., Ottawa, ON, Canada Reem Hamdy Mohammed, Nishihar, Japan Ph.D. Ohio M.D., Ph.D. Bangkok, Thailand Robin M. Yates, D.V.M., Ph.D. Gulnur Kozhachmet Giza, Egypt Heather R. Strange, M.S. Calgary, AB, Canada Zakiryanova, M.D., Ph.D. Joanna E. Brewer, Ph.D. Columbus, OH Yi Hao, M.D., Ph.D. Almaty, Kazakhstan Oxon, United Kingdom Susan M. Bueno, Ph.D. Paris, France Santiago, Chile Claudia Gonzalez-Espinosa, Jeremy Stuart Brown, Oregon David Klatzmann, M.D., Ph.D. Ph.D. M.B.B.S., Ph.D. Carolyn A. DeMarco, M.S. Min Cui, Ph.D. Paris, France Tlalpan, Mexico London, United Kingdom Eugene, OR Wuhan, China Stephane M. Paul, Ph.D. Yolanda Lopez-Vidal, M.D. John A. Hammond, Ph.D. Bing Du, Ph.D. Pennsylvania Saint-Etienne, France Mexico City, Mexico Woking, United Kingdom Shanghai, China Xuanhong Cheng, Ph.D. Asier Saez-Cirion, Ph.D. Rafael Saavedra, Ph.D. James A. Harker, Ph.D. Bethlehem, PA Xiao-Ming Gao, Ph.D. Paris, France Mexico City, Mexico London, United Kingdom Suzhou, China De Gaulle Igbodiegwu Maria Leptin, Ph.D. Valeria Ramaglia, Ph.D. John Maher, MBChB, Ph.D. Chigbu, M.S. Yanfeng Gao, Ph.D. Heidelberg, Germany Amsterdam, Netherlands London, United Kingdom Philadelphia, PA Zhengzhou, China Ramin Lotfi, M.D., Ph.D. Jos P. van Putten, M.D., Ph.D. James E. Pease, Ph.D. Sheri Dubey, M.S. Weiguo Hu, M.D., Ph.D. Ulm, Germany Utrecht, Netherlands London, United Kingdom West Point, PA Shanghai, China Eva Medina, Ph.D. Moses Ode Odugbo, Ph.D. Boris Rodenko, Ph.D. Kimberly Johnston, M.S. Zun-Ji Ke, M.D., Ph.D. Braunschweig, Germany Vom, Nigeria Glasgow, United Kingdom Doylestown, PA Shanghai, China Renata Stripecke, Ph.D. Gyri Teien Haugland, Ph.D. Christine Anne Wells, Ph.D. Qibin Leng, Ph.D. Tennessee Hannover, Germany Bergen, Norway Glasgow, United Kingdom Shanghai, China Joyce L. Azevedo, Ph.D. Alexander N.R. Weber, M.P.H., Hamza N. Hanieh, Ph.D. Timothy James Wilson, Ph.D. Guangxun Meng, Ph.D. Collegedale, TN Ph.D. Hofouf, Saudi Arabia Cambridge, United Kingdom Shanghai, China Tuebingen, Germany Anwar M. Hashem, Ph.D. Mo Yin Mok, M.B.B.S., M.D. Bhaskar Saha, Ph.D. Jeddah, Saudi Arabia Hong Kong, China ASSOCIATE Pune, India ASSOCIATE Masood A. Khan, Ph.D. International Bing Ni, Ph.D. Jan Emmerich, Ph.D. Buraydah, Saudi Arabia United States Chongging, China Bodour A. AlKhamees, M.S. Dublin, Ireland Florent Ginhoux, Ph.D. California London, ON, Canada Hai Qi, Ph.D. Yoram Louzoun, Ph.D. Singapore, Singapore Shelton S. Herbert, Ph.D. Beijing, China Hongwei Ma, Ph.D. Ramat Gan, Israel Angwin, CA Ho Liam Pock, M.B.B.S. Suzhou, China Xiao Su, M.D., Ph.D. Guido Ferlazzo, M.D. Singapore, Singapore Patrick P. Jones, B.S. Shanghai, China Qiang Shu, M.D. Messina, Italy San Francisco, CA Yong-Soo Bae, Ph.D. Hangzhou, China Honglin Wang, Ph.D. Ursula Grohmann, Ph.D. Suwon, South Korea Don Weldon, B.S. Shanghai, China Zhe Liu, Ph.D. Perugia, Italy Temecula, CA Tae-Hwe Heo, Ph.D. London, United Kingdom Pingli Wang, M.D., Ph.D. Anna Mondino, Ph.D. Bucheon, South Korea Hangzhou, China Connecticut Milan, Italy Jong-Hwan Park, D.V.M., Zhiliang Wang, M.D. Thomas J. Terenzi, D.O. Masataka Haneda, M.D., Ph.D. Tianjin, China Portland, CT Ph.D. Daejeon, South Korea Hui Xiao, Ph.D. Nagoya, Japan Florida Ju-Young Seoh, M.D., Ph.D. Shanghai, China Kazuhiro Iwai, M.D., Ph.D. Seoul, South Korea Ali Saharkhiz-Langroodi, D.O., Jianqing Xu, M.D., Ph.D. Kyoto, Japan Ph.D. Domingo F. Barber, Ph.D. Shanghai, China Fort Myers, FL Hidemitsu Kitamura, Ph.D. Madrid, Spain Lin Xu, Sr., Ph.D. Sapporo, Japan Gunilla B. Karlsson Georgia Zunyi, China Tomomitsu Miyasaka, Ph.D. Hedestam, Ph.D. Yibing Peng, D.M.D., M.B.B.S. Qiang Xu, D.O., Ph.D. Sendai, Japan Stockholm, Sweden Augusta, GA Nanjing, China Yasuhiko Nishioka, M.D., Gunnar Pejler, Ph.D. Illinois Huaqiang Yang, Ph.D. Ph.D. Uppsala, Sweden Guangzhou, China Tokushima, Japan Frank William Soveg, B.S. Christopher Sundling, Ph.D. Chicago, IL Tomonori Nochi, Ph.D. Stockholm, Sweden Sendai, Japan

28 AAI Newsletter Winter 2014-2015 www.aai.org AAI Newsletter 29 Meetings and Events Calendar Mark Your Calendar for These Important Dates!

2015 January 24–27, 2015 July 14–19, 2015 November 5–8, 2015 54th Midwinter Conference of AAI Introductory Course in Immunology 14th International Workshop on Immunologists at Asilomar Long Beach Convention Center Langerhans Cells Asilomar Conference Grounds, Long Beach, CA Kyoto, Japan Pacific Grove (near Monterey), CA aai.org/Education/Courses/Intro/index.htm lc2015.jp midwconfimmunol.org February 11–15, 2015 August 2–7, 2015 2016 2015 BMT Tandem Meeting AAI Advanced Course in Immunology San Diego, CA Seaport World Trade Center February 18–22, 2016 cibmtr.org/Meetings/Tandem/index.html Boston, MA 2016 BMT Tandem Meeting aai.org/Education/Courses/Advanced/ Honolulu, HI March 28–April 1, 2015 index.html cibmtr.org/Meetings/Tandem/index.html Experimental Biology (EB) (APS, ASPET, ASIP, ASN, AAA, ASBMB) September 6–9, 2015 May 13–17, 2016 Boston, MA ™ ECI 2015: 4th European Congress of IMMUNOLOGY 2016 Contact: [email protected] Immunology AAI Annual Meeting Vienna, Austria Washington State Convention Center May 8–12, 2015 eci-vienna2015.org Seattle, WA ™ IMMUNOLOGY 2015 AAI aai.org/Meetings/Future_Meeting.html Annual Meeting September 27-29, 2015 Ernest N. Morial Convention Center 48th Annual Meeting of the August 21–26, 2016 New Orleans, LA ™ Society for Leukocyte Biology, ICI 2016: International Congress of immunology2015.org “Immunity in Health and Disease” Immunology 2016 Raleigh, NC Melbourne, Australia June 14–19, 2015 http://leukocytebiology.org/Meetings/ ici2016.org Upcoming-SLB-Meetings.aspx First International Convention: IMMUNOLOGY 2015 IMMUNOPHARMACOLOGY - October 6–9, 2015 VACCIPHARMA 2015 2017 SAVE THE DATE Influenza Vaccines for the World IVW 2015 Melia Marina Varadero Albufeira, Portugal May 12–16, 2017 Varadero Beach, Cuba MAY 8-12, 2015 ERNEST N. MORIAL CONVENTION CENTER NEW ORLEANS, LA meetingsmanagement.cmail2.com/t/d-l-vpity- IMMUNOLOGY 2017™ scf.sld.cu vckugr-t AAI Annual Meeting July 10–12, 2015 Walter E. Washington Convention Center October 9–12, 2015 LACA 2015, 5th Latin American Congress Washington, D.C. ASBMR 37th Annual Meeting on Autoimmunity aai.org/Meetings/Future_Meeting.html Seattle, WA Salvador, Bahia, Brazil asbmr.org http://laca.kenes.com/

July 11–15, 2015 October 11–14, 2015 American Society for Virology 34th Cytokines2015 Annual Scientific Meeting Bamberg, Germany University of Western Ontario, London, www.cytokines2015.com Ontario, Canada www.asv.org/

Track updated meeting listings anytime via the online Meetings and Events Calendar – visit http://www.aai.org/Careers/Calendar/index.html.

30 AAI Newsletter Winter 2014-2015 IMMUNOLOGY2015.org Meetings and Events Calendar

IMMUNOLOGY 2015 ™ SAVE THE DATE MAY 8-12, 2015 ERNEST N. MORIAL CONVENTION CENTER NEW ORLEANS, LA

30 AAI Newsletter Winter 2014-2015 IMMUNOLOGY2015.org THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS NONPROFIT ORG 9650 Rockville Pike, Bethesda, MD 20814-3994 US POSTAGE PAID BETHESDA, MD PERMIT NO. 1126

AAI Invites Additions to List of Women Speakers

The AAI Committee on the Status of Women (CSOW) has revamped the format of the List of Potential Speakers and Chairs. (See the November/December In addition to representing a broader range of 2013 AAI Newsletter, page 39.) The committee also leadership roles occupied by women, the list will announced a new process for individuals to have be more accessible and more easily maintained. their names added to the list. The changes are Individuals listed will be able to maintain their intended to broaden the range of areas of expertise own entries as each now links to the individual’s of AAI members and to make the list more Web page. accessible and accurate as a resource for enhancing opportunities for women as speakers or chairs Viewers can determine how well the profile at professional meetings. matches their need for a woman immunologist in a particular leadership role. Listings were originally limited to women serving as heads of immunological research labs, but the Women currently listed must supply their URLs to CSOW Speaker List is now open to women AAI remain on the list. To be added to the list, contact members fulfilling leadership roles in non-research Mary Bradshaw, AAI staff liaison for the CSOW careers as well. ([email protected]).

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