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The University News, Vol. 5, No. 8, May 31, 1979
VOL5N08 MAY 311979 Newsletter for I( The University of Newcastle New Oval Mater ial isi ng Enrolments Enrolment oJ students as at . April 30 totalled 4364 compared with 4429 in 1978. This rep resents an annual rate of decrease of 1% compared with 4% for 1977-78. The enrolment for higher degrees increased this year from 391 to 403 - a gain of 3%. There has been a 2% fall in the enrolment in other than higher degrees, now 3961 as against 4038 in 1978. Of the total enrolment 55% is full-time and 45% part-time. This compares wit~ 58% and 42% respectively in 1978. In terms of students the full-time enrol ment is 2392 and the part-time 1937. The male student numbers are 2735 or 63% of the total, and the female enrolment 1629. A combination of favourable When construction commenced earl or 37%. In 1978. 64% was male growing conditions and fertiliz ier this year sufficient finance and 36% female. ation has allowed rapid progress was available to complete only half of the project. Now it has The number of students from to be made with work on NO.3 overseas has continued to fall Oval. The Electricity Commission been decided to complete the from 188 in 1977, 160 in 1978 of New South Wales and the entire oval in the very near to 145 in 1979. University are jointly construct future. tng the playing area, which The University will have the use The greater number of our over covers almost the same area as of the oval for an initial period seas students came from: NO.1 Oval. -
Melbourne Health Annual Report 2007/08
Melbourne Health Annual Report 2007/08 1BTTJPOGPS $BSJOH"DIJFWJOH UIF&YUSBPSEJOBSZ PROFILE Prof Graham Brown There was none more deserving of the 2007 Melbourne Health Chairman’s Award than Prof Graham Brown. Prof Brown, an acclaimed infectious diseases physician, researcher and teacher, is passionate about public health and is highly regarded by colleagues for his outstanding leadership, intellect and ethical standards. Prof Brown this year took up the role of Foundation Director of the Nossal Institute for Global Health and Foundation Chair in Global Health at the University of Melbourne. Prof Brown’s association with Melbourne Health began as a medical student at RMH, then as a resident, medical registrar, consultant and ultimately, as the James Stewart Professor of Medicine. In 1996, he established the hospital’s renowned Victorian Infectious Diseases Service, taking responsibility for the many services transferred from the former Fairfi eld Infectious Diseases Hospital. “It was almost by chance that I ended up in Medical School, and incredible good fortune to be trained in the environment of RMH that valued academic- based medicine with strong links to Melbourne University. The mentorship, the collegiality, the pursuit of excellence, the challenging students, the superb nursing and allied health staff, and above all, the concern and care for every patient, set very high standards and a benchmark for my career in medicine.” CONTENT 43 Financial Statements 44 Operating Statement 45 Balance Sheet Contents 46 Cash Flow Statement 2 Chairman’s -
Pfcerli1 Is a Conserved Rhoptry Associated Protein Essential for Plasmodium Falciparum Merozoite Invasion of Erythrocytes
ARTICLE https://doi.org/10.1038/s41467-020-15127-w OPEN PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes Benjamin Liffner 1,8, Sonja Frölich 1,8, Gary K. Heinemann2, Boyin Liu3, Stuart A. Ralph 3, ✉ Matthew W.A. Dixon 3, Tim-Wolf Gilberger4,5,6 & Danny W. Wilson 1,7 1234567890():,; The disease-causing blood-stage of the Plasmodium falciparum lifecycle begins with invasion of human erythrocytes by merozoites. Many vaccine candidates with key roles in binding to the erythrocyte surface and entry are secreted from the large bulb-like rhoptry organelles at the apical tip of the merozoite. Here we identify an essential role for the conserved protein P. falciparum Cytosolically Exposed Rhoptry Leaflet Interacting protein 1 (PfCERLI1) in rhoptry function. We show that PfCERLI1 localises to the cytosolic face of the rhoptry bulb membrane and knockdown of PfCERLI1 inhibits merozoite invasion. While schizogony and merozoite organelle biogenesis appear normal, biochemical techniques and semi-quantitative super- resolution microscopy show that PfCERLI1 knockdown prevents secretion of key rhoptry antigens that coordinate merozoite invasion. PfCERLI1 is a rhoptry associated protein iden- tified to have a direct role in function of this essential merozoite invasion organelle, which has broader implications for understanding apicomplexan invasion biology. 1 Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA 5005, Australia. 2 Experimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, Adelaide, SA 5005, Australia. 3 Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia. -
Melbourne Biomedical Precinct Studley Rd to an Exceptional Network Economic and Investment Growth Swinburne University of of Skilled Workers, Quality for the State
The Royal Children’s Hospital + The Murdoch Children’s Research Institute The Royal Women’s Hospital Darwin Walter & Eliza Hall Institute Monash Institute of Pharmaceutical NT Science, Monash University + CSIRO QLD Royal Melbourne Hospital WA Brisbane C Florey Institute SA e m ete ry Rd The University of Melbourne NSW Perth Sydney A Precinct approach Victorian Comprehensive Cancer Centre Adelaide Royal Pde Canberra + Peter MacCallum Cancer Centre The Doherty Institute to collaboration Flemington Rd Elgin St St Vincent’s Hospital Melbourne Hobart Melbourne, Grattan St Swanston St Australia and innovation Arden St Curzon St Elizabeth St Lygon St La Trobe University Queensberry St d R g r e b Burgundy St Rathdowne St l Chetwynd St Victoria St e > id e Melbourne Brain Centre H r Peel St e Austin Health p Plan Melbourne, Victoria’s key metropolitan Franklin St p Melbourne has biomedical La Trobe St U Austin Hospital planning strategy, highlights the precincts Banksia St capabilities unparalleled in around Melbourne, Monash, Deakin, Olivia Newton-John Australia and amongst the and La Trobe universities as clusters CSL Cancer Wellness & world’s best. We are home which offer significant opportunities (Poplar Road) Research Centre for innovation as well as employment, Melbourne Biomedical Precinct Studley Rd to an exceptional network economic and investment growth Swinburne University of of skilled workers, quality for the state. Technology education providers, leading The Melbourne Biomedical Precinct Deakin University St Kilda Rd research institutes and a Partners are largely collocated to the Princes Hwy Commercial Rd Burwood & Geelong Campuses sophisticated health system. north of Melbourne’s CBD close to Monash University, Australia’s highest ranking university, Clayton � Caulfield There is a growing body of evidence the University of Melbourne. -
2010-2011 Annual Report
Annual Report 2010-2011 Mastery of disease through discovery | www.wehi.edu.au Contents 1 About the institute 3 Director’s and Chairman’s report 5 Discovery 8 Cancer and Haematology 10 Stem Cells and Cancer 12 Molecular Genetics of Cancer 14 Chemical Biology 16 Molecular Medicine 18 Structural Biology 20 Bioinformatics 22 Infection and Immunity 24 Immunology The Walter and Eliza Hall Institute 26 Autoimmunity and Transplantation of Medical Research 28 Cell Signalling and Cell Death 1G Royal Parade 30 Inflammation Parkville Victoria 3052 Australia Telephone: (+61 3) 9345 2555 32 Molecular Immunology Facsimile: (+61 3) 9347 0852 34 Publications WEHI Biotechnology Centre 36 Awards 4 Research Avenue 37 Translation La Trobe R&D Park Bundoora Victoria 3086 Australia Translating our research 38 Telephone: (+61 3) 9345 2200 40 Developing our research Facsimile: (+61 3) 9345 2211 42 Patents www.wehi.edu.au www.facebook.com/WEHIresearch 43 Education www.twitter.com/WEHI_research 46 2010-11 graduates ABN 12 004 251 423 47 Seminars Acknowledgements 48 Institute awards Produced by the institute’s Community Relations department 49 Engagement Managing editor: Penny Fannin Editor: Liz Williams 51 Strategic partners Writers: Liz Williams, Vanessa Solomon and Julie Tester 52 Scientific and medical community Design and production: Simon Taplin Photography: Czesia Markiewicz and Cameron Wells 54 Public engagement 57 Engagement with schools Cover image 58 Donor and bequestor engagement Art in Science finalist 2010 Vessel webs 59 Sustainability Dr Leigh Coultas, Cancer and Haematology division 60 The Board This image shows the delicate intricacy in the developing eye of a transient population of web-like blood vessels. -
Human DECR1 Is an Androgen-Repressed Survival Factor
RESEARCH ARTICLE Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis Zeyad D Nassar1,2†, Chui Yan Mah1,2†, Jonas Dehairs3, Ingrid JG Burvenich4, Swati Irani1,2, Margaret M Centenera1,2, Madison Helm1,2, Raj K Shrestha5, Max Moldovan2, Anthony S Don6, Jeff Holst7, Andrew M Scott4, Lisa G Horvath8, David J Lynn2,9, Luke A Selth1,5,9, Andrew J Hoy10, Johannes V Swinnen3, Lisa M Butler1,2* 1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, Australia; 2South Australian Health and Medical Research Institute, Adelaide, Australia; 3KU Leuven- University of Leuven, LKI- Leuven Cancer Institute, Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, Belgium; 4Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, Australia; 5Dame Roma Mitchell Cancer Research Laboratories, University of Adelaide, Adelaide, Australia; 6NHMRC Clinical Trials Centre, and Centenary Institute, The University of Sydney, Camperdown, Australia; 7Translational Cancer Metabolism Laboratory, School of Medical Sciences and Prince of Wales Clinical School, UNSW Sydney, Sydney, Australia; 8Garvan Institute of Medical Research, NSW 2010; University of Sydney, NSW 2006; and University of New South Wales, Darlinghurst, Australia; 9College of Medicine and Public Health, Flinders University, Bedford Park, Australia; 10Discipline of Physiology, School of *For correspondence: Medical Sciences, Charles Perkins Centre, Faculty of Medicine and Health, The [email protected] University of Sydney, Camperdown, Australia †These authors contributed equally to this work Competing interests: The b authors declare that no Abstract Fatty acid -oxidation (FAO) is the main bioenergetic pathway in human prostate competing interests exist. -
University of Melbourne Annualreport2017 Fullreport
Annual Report 2017 unimelb.edu.au Contents Chancellor’s letter 1 VC’s introduction 2 The Melbourne Vision 3 Our past, present and future 4 2017 timeline 6 At a glance 8 Five-year statistics 10 Growing Esteem 12 Chapters in brief 14 Teaching, Learning and the Student Experience 16 Research 34 Engagement 48 Sustainability 64 Staff honours 78 High-achieving students 80 University governance 82 Council members 83 Academic governance 86 Governance structure 87 Senior leadership/University management 88 Statutory reporting 92 Financial report 105 Financial report index 106 Financial statement overview 107 Five-year financial summary 110 Financial statements 114 Disclosure index 166 Glossary 169 Index 171 | Front cover: ‘Eagle nest’, 2011, acrylic on canvas by Wurundjeri/Yorta Yorta artist and researcher, Ashley Kerr-Firebrace, is an intricate depiction of Wurundjeri creator Bunjil (the eagle) standing strong in the nest and supported by country, culture and people. The University of Melbourne stands on the land of the Wurundjeri people of the Kulin Nations. Ashley is the son of Wurundjeri Elder, Aunty Diane Kerr, who was born in Carlton, lives on Country and performs the Wominjeka (Welcome) to Country at University of Melbourne events and ceremonies. The Hon. Gayle Tierney MLC Minister for Training and Skills Level 1, 2 Treasury Place East Melbourne Vic 3002 16 March 2018 Dear Minister In accordance with the requirements of regulations and financial reporting directions under the Financial Management Act 1994, I am pleased to submit for your information and presentation to Parliament the Annual Report of the University of Melbourne for the year ending 31 December 2017. -
DECR1 Is an Androgen-Repressed Survival Factor That Regulates PUFA Oxidation To
bioRxiv preprint doi: https://doi.org/10.1101/865626; this version posted December 6, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis Zeyad D. Nassar1,2*, Chui Yan Mah1,2*, Jonas Dehairs3, Ingrid J.G. Burvenich4, Swati Irani1,2, Margaret M. Centenera1,2, Raj K. Shrestha5, Max Moldovan2, Anthony S. Don6, Andrew M. Scott4, Lisa G. Horvath7, David J. Lynn2,8, Luke A. Selth1,5,8, Andrew J. Hoy9, Johannes V. Swinnen3, Lisa M. Butler1,2# 1 University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia 2 South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia 3 KU Leuven- University of Leuven, LKI- Leuven Cancer Institute, Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, B-3000, Belgium 4 Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia 5 Dame Roma Mitchell Cancer Research Laboratories, University of Adelaide, Adelaide, SA 5005, Australia 6 NHMRC Clinical Trials Centre, and Centenary Institute, The University of Sydney, Camperdown, NSW 2006, Australia 7 Garvan Institute of Medical Research, Darlinghurst, NSW 2010; University of Sydney, Camperdown, NSW 2006; and University of New South Wales, Sydney, NSW 2052, Australia 8 College of Medicine and Public Health, Flinders University, Bedford Park, SA 5042, Australia 1 bioRxiv preprint doi: https://doi.org/10.1101/865626; this version posted December 6, 2019. -
CSL Research - Investor Site Tour @ Bio21 Institute 30 April 2018
CSL Research - Investor Site Tour @ Bio21 Institute 30 April 2018 CSL Research • Bio21 / Parkville, Marburg, Bern • Protein, gene & cell based therapies Specialty Breakthrough Immunoglobulins Haemophilia Transplantation Products Medicines • ~200 staff • Molecular Biology, Protein Biochemistry, Cell Biology & Physiology, Bioinformatics, Research & Clinical Analytics, Pharm/Tox Plasma Protein Science & Discovery 2 | Driven by Our Promise™ Global Hub for Research & Translational Medicine • New laboratories being constructed on the Bio21 site, 3628m2 • CSL space from 1470m2 to 3500m2 • Capacity to increase from 75 FTE’s to 165 (relocation from PKV) • University of Melbourne to fund construction • CSL to fund fit-out of CSL space • Construction commenced Q3 2016 with fit-out completed Q3 2018 3 | Driven by Our Promise™ Melbourne / Parkville Biomedical Precinct • a CSL competitive advantage Bio21 CSL 4 | Driven by Our Promise™ Melbourne / Parkville Biomedical Precinct • a CSL competitive advantage Melb. University Royal Melb. Florey Inst. Medical School Hospital Neuroscience Doherty Inst. Immunol. Microbiol Aust. Genomics Research Facility Victorian Comprehensive Cancer Centre Peter Mac WEHI Bio21 Cancer Inst. Women’s Hospital Royal Children's Murdoch Research Hospital Institute 5 | Driven by Our Promise™ WEHI / CSL Bioinformatics Alliance WEHI - world leaders in bioinformatic software development • By research specialty - differential expression - regulation of gene expression - cancer genome analysis - statistical genetics - molecular epidemiology -
The Bio21 Institute's 2020 Annual Report Is Available to Download
Annual Report 2020 Image of the coronavirus SARS-CoV-2 taken by Andrew Leis and Jason Roberts. Courtesy of the Doherty Institute. The Bio21 Molecular Science and Director Associate Director – Platform Biotechnology Institute Professor Michael W. Parker Infrastructure University of Melbourne DPhil (Oxon) FAA FAHMS Professor Malcolm McConville PhD 30 Flemington Road Deputy Director Associate Director – Commercialisation Parkville Victoria 3010 Professor Frances Separovic AO Professor Spencer Williams PhD Telephone: (03) 8344 2220 PhD FAA www.bio21.unimelb.edu.au Associate Director – Engagement @Bio21Institute Professor Sally Gras PhD @Bio21Institute Scientific Research Manager Dr David Keizer, PhD Produced by the Bio21 Molecular Science and Biotechnology External Relations Advisor,b Bio21 Florienne Institute Loder Annual Report 2020 Contents Our Mission 2 Our Vision 2 About the Institute 3 Director’s Message 4 Bio21 Leadership 8 Deputy Director, Professor Emeritus Frances Separovic AO 8 Associate Director Engagement – Professor Sally Gras 10 Associate Director Commercialisation – Professor Spencer Williams 13 Associate Director Platform Infrastructure – Professor Malcolm McConville 14 ACRF Facility for Innovative Cancer Drug Discovery 16 Impacts of Research 19 OHS Report 31 Equity Diversity and Inclusion 32 Industry Engagement and Commercialisation 35 Announcing the Ruth Bishop Building and Ian Holmes Imaging Centre 36 Events and Conferences 39 Graduate Research Students and Early Career Researchers 41 Institute Members Honoured 42 Grant Successes 43 Governance 46 Bio21 Scientific Research Team 47 Bio21 Research Groups 48 Bio21 People 50 Institute in Numbers 56 Bio21 Institute Theses submitted in 2020 57 Bio21 Steering Committee 58 Industry partners 63 Produced by the Bio21 Molecular Science aFontn Front cover image: Bio21 precinct aerial photograph, courtesy of Kane Jarrod Photography. -
June 2015.Indd
Australasian Society for Immunology Inc. NEWSLETTER PP 100000910 ISSN 1442-8725 June 2015 ContentsContents Feature article: Immunology & Cell Biology 3 Editorial 6 Christina Cheers: Hon. Life Member 8 2014 Jomar Poster Prize Winner 12 3D reconstruction of a murine lymph node. Honorary Secretary’s News 14 red: blood vessels, green: dextran-labelled phagocytes, grey: lymphatic sinuses. Lupus Research at Monash University 15 Inken Kelch and colleagues (see page 2) Visiting Speaker Program 20 Upcoming Conferences 10 Day of Immunology 22 Councillors’ News 27 Travel Award Conference Reports 30 Publications List 32 ASI Inc. Newsletter June 2015 ASI Inc. COUNCIL Non-Voting Councillors: Newsletter Editor President Past President Ms Joanna Roberts Professor Christopher Goodnow Professor Dale Godfrey Ph: 64 6 357 0654 Department Immunology Dept of Microbiology & Immunology Email: [email protected] JCSMR, ANU Peter Doherty Institute PO Box 334, Canberra ACT 2601 University of Melbourne Parkville Vic 3010 Journal Editor Ph: 61 2 6125 2394 Ph: 61 3 8344 6831 Dr Gabrielle Belz Email: [email protected] Email: [email protected] Ph: 61 3 9345 2544 Email: [email protected] Honorary Secretary Honorary Treasurer A/Prof. Stuart Berzins Dr John Stambas Visiting Speakers Co-ordinator CRN Section, School of Health Sciences AAHL, CSIRO Deakin Collaborative Lab. Dr Joanna Kirman Federation University Australia Private Bag 24 Ph: 64 3 479 7712 Mt Helen Vic 3352 East Geelong Vic 3220 Email: [email protected] Ph: 61 3 5320 2039 Ph: 61 3 5227 -
2Nd Postdoc Methods Symposium Program
Program Thursday, 13th September Event Approximate Time Location Registration Opens 8:30 – 9:00 Tapestry Lounge (in front of the Davis Auditorium) Session 1 9:00 – 10:20 Davis Auditorium 9:00 – 9:05 Organising Committee Welcome and Introductions 9:05 – 9:20 Daniel Brown An overview of single-cell omics methods, from Walter and Eliza Hall Institute technology to applications 9:20 – 9:35 Belinda Phipson Kidneys in a dish: examining the reproducibility Murdoch Children’s Research Institute of organoid differentiation using transcriptomics 9:35 – 9:50 Joanna Sacharz SELEX: In search of solubilizing nucleic acids Bio21 Institute, University of Melbourne KEYNOTE: A primer on single cell RNA-seq analysis 9:50 – 10:20 Matthew Richie Walter and Eliza Hall Institute Morning Tea 10:20 – 11:00 Tapestry Lounge posters & sponsor exhibits 2nd Postdoctoral Methods Symposium 2018 #PDMS2018 Event Approximate Time Location Session 2 11:00 – 12:15 Davis Auditorium MCFP sponsored talk Biological Imaging via Helium ion Microscopy 11:00 – 11:15 Babak Nasr University of Melbourne 11:15 – 11:30 Mohamed Fareh Single-molecule fluorescence reveals the Peter MacCallum Cancer Centre dynamics of microRNA recognition by Dicer- TRBP complex 11:30 – 11:45 Charis Teh Capturing the cellular gymnastics of survival Walter and Eliza Hall institute and killer proteins by mass cytometry (CyTOF) 11:45 – 12:00 Jieqiong Lou Phasor analysis and image correlation Bio21 Institute, University of Melbourne spectroscopy of histone FLIM/FRET reveals spatiotemporal regulation of chromatin organization by the DNA damage response. Session 2 Flash talks 12:00 – 12:15 Davis Auditorium Rachel Lundie Flow FISH as a method to elucidate the Walter and Eliza Hall Institute transcriptional effects of M.