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Australasian Society for Immunology Inc. NEWSLETTER PP 100000910 ISSN 1442-8725 June 2015 ContentsContents Feature article: Immunology & Cell Biology 3 Editorial 6 Christina Cheers: Hon. Life Member 8 2014 Jomar Poster Prize Winner 12 3D reconstruction of a murine lymph node. Honorary Secretary’s News 14 red: blood vessels, green: dextran-labelled phagocytes, grey: lymphatic sinuses. Lupus Research at Monash University 15 Inken Kelch and colleagues (see page 2) Visiting Speaker Program 20 Upcoming Conferences 10 Day of Immunology 22 Councillors’ News 27 Travel Award Conference Reports 30 Publications List 32 ASI Inc. Newsletter June 2015 ASI Inc. COUNCIL Non-Voting Councillors: Newsletter Editor President Past President Ms Joanna Roberts Professor Christopher Goodnow Professor Dale Godfrey Ph: 64 6 357 0654 Department Immunology Dept of Microbiology & Immunology Email: [email protected] JCSMR, ANU Peter Doherty Institute PO Box 334, Canberra ACT 2601 University of Melbourne Parkville Vic 3010 Journal Editor Ph: 61 2 6125 2394 Ph: 61 3 8344 6831 Dr Gabrielle Belz Email: [email protected] Email: [email protected] Ph: 61 3 9345 2544 Email: [email protected] Honorary Secretary Honorary Treasurer A/Prof. Stuart Berzins Dr John Stambas Visiting Speakers Co-ordinator CRN Section, School of Health Sciences AAHL, CSIRO Deakin Collaborative Lab. Dr Joanna Kirman Federation University Australia Private Bag 24 Ph: 64 3 479 7712 Mt Helen Vic 3352 East Geelong Vic 3220 Email: [email protected] Ph: 61 3 5320 2039 Ph: 61 3 5227 5740 Email: [email protected] Email: [email protected] Day of Immunology Co-ordinator Dr Claerwen Jones Deputy Treasurer Ph: 61 3 8344 9595 Dr Kim Jacobson Email: [email protected] Walter & Eliza Hall Institute 1G Royal Parade, Parkville Vic 3052 Meeting Co-ordinator Email: [email protected] Dr Susanne Heinzel Ph: 61 3 9345 2609 Branch Councillors Email: [email protected] New South Wales Victoria & Tasmania Dr Mainthan Palendira Dr Daniel Gray Council Member of IUIS Ph: 61 2 9565 6211 Ph: 61 3 9345 2497 Professor Alan Baxter Email: [email protected] Email: [email protected] Ph: 61 7 4781 6265 Email: [email protected] Queensland South Australia & Northern Territory Dr Kristen Radford Dr Cara Fraser FIMSA Councillor Ph: 61 7 3443 7638 Ph: 0422 903 093 Professor Alan Baxter Email: [email protected] Email: [email protected] Ph: 61 7 4781 6265 Email: [email protected] Western Australia Australian Capital Territory Dr Andrew Currie Dr Anselm Enders Honorary Archivist: Ph: 61 8 9360 7426 Ph: 61 2 6125 7605 Dr Judith Greer Email: [email protected] Email: [email protected] Ph: 61 7 3346 6018 Email: [email protected] New Zealand Dr Roslyn Kemp Ph: 64 3 479 7708 Administrative Correspondence Email: [email protected] Ms Judi Anderson Project Manager ASI Inc. Secretariat Miss Sarah Fardy PO Box 7108 Ph: 61 3 5227 5794 / 0413 917 990 Upper Ferntree Gully Vic 3156 Email: [email protected] Ph: 61 3 9756 0128 Email: [email protected] Cover Image: 3D reconstruction of a murine lymph node Inken Kelch1,2 Gib Bogle1,3 Greg Sands3 Anthony Phillips1,2,4 Dane Gerneke3 Ian LeGrice3,5 Rod Dunbar1,2 1. Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, NZ 2. School of Biological Sciences, University of Auckland, Auckland, NZ 3. Auckland Bioengineering Institute, University of Auckland, Auckland, NZ 4. Department of Surgery, University of Auckland, Auckland, NZ 5. Department of Physiology, University of Auckland, Auckland, NZ The image was taken during my (Inken’s) PhD using a specialised confocal microscope, able to resolve fi ne subcellular structures across large tissue regions such as entire murine lymph nodes. The aim of the multidisciplinary project was to image critical structures for immune function in whole lymph nodes and make them available for detailed computer analysis in 3D. With the help of the specialised imaging platform (Ian LeGrice, Greg Sands, Dane Gerneke) and custom-written computer tools (Gib Bogle) we studied the topology of the blood vessel system and the distribution of lymphatic channels, the main routes for cell traffi c and information distribution within lymph nodes. Our ongoing studies are concerned with the anatomical changes of these structures following an immune challenge, the antigen distribution within lymph nodes, and the positioning of supportive cell populations. 2 ASI Inc. Newsletter June 2015 IMMUNOLOGY & CELL BIOLOGY: FROM POSSUM’S PAGES TO LEADING IMMUNOLOGY JOURNAL Immunology & Cell Biology is the cornerstone journal of the Australasian Society for Immunology and is now joined by its sister journal Clinical & Translational Immunology. Gabriele Belz, Editor-in-Chief, Immunology & Cell Biology Division of Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria, 3052. Australia It’s Your Journal! In 2014, Immunology & Cell Biology celebrated its 90th year and has been host to a number of highly infl uential pioneering reports including those by McFarlane Burnett and Don Metcalf. Weathering the ups and downs of the last nine decades is testament to the quality and enduring nature of the journal. Continuing on the excellence in Volume 93 Number 5 May/June 2015 www.nature.com/icb publishing established over this period, the journal aims to attract the highest quality research in the cellular immunology fi eld. The journal publishes primary research articles but also stands out from other journals by collections of reviews as Special Features and Outstanding Observations. Our most recent Special Feature collection focuses on Epigenetics (www.nature.com/ icb/journal/v93/n3). The journals are of critical importance to the ASI as they • provide key platforms for fi nancially supporting the ASI and the activities that are funded through the Society (e.g. ASI Visiting Speaker Program, regional activities, travel awards); • are central places for the publication of high quality research; • are critical for building our international presence for the Australasian immunology community. Impact Factor: 4.205 (ISI Journal Citation • Special Feature Collections – Focus Meet the Team Reports ®, Thomson Reuters, 2014) issues, e.g. March 2015 Edition: Immunology & Cell Biology is overseen by Features: Epigenetics (www.nature.com/icb/ a vibrant team which implements the review journal/v93/n3). process of submitted articles and promotes • Rapid time to fi rst decision • Signifi cant exposure through Nature the development of the journal on behalf of • Accepted articles available online Publishing Group your society, ASI. within 72 hours of acceptance into production Location: www.nature.com/icb Simone Farrer: Simone is the Editorial Assistant for both ICB and CTI and is central • Outstanding Observations – rapid I encourage all ASI members to consider ICB for co-ordinating the engine house of the publication (14 days to fi rst decision) of cutting edge fi ndings for publication of their next paper. journal. Simone holds a MSc degree from University of Melbourne, where she studied the structure of hybrid zones in the common terrestrial toadlets of south-east Australia 3 ASI Inc. Newsletter June 2015 regulation of the development of these cells. More recently, she has developed a major theme focusing on mucosal immunology and the role of recently discovered innate immune lymphocytes which form their own front line defense preceding initiation of the adaptive immune response. She has more than 144 peer-reviewed research articles and invited reviews and in 2008, she received the Gottschalk Medal from the Australian Academy of Sciences. I encourage all ASI members to consider ICB for publication of their next paper Adrian Liston Adrian Liston, Deputy Editor. Adrian is Simone Farrer an immunologist, trained fi rst at Adelaide University, and then obtained his PhD at (which are related to the alpine Corroboree the Australian National University. He then frog) with Drs Murray Littlejohn and Graeme undertook a post-doc in Seattle (USA) with Watson. She brought to her position extensive Alexander Rudensky. In 2009, he established experience both in editing and publishing his own laboratory, the Autoimmune Genetics through 18 years in editorial roles at CSIRO Laboratory, at the VIB in Belgium. His main Publishing from 1991 to 2009 where she scientifi c interest is in understanding the worked with several zoological and botanical genetic control over the immunogenic/ journals as a Production Editor and Managing tolerogenic balance of T cells, critical for Editor. Simone took over the running of the preventing immune pathology. ICB Editorial Offi ce in 2010. Stuart Tangye Stuart Tangye, Deputy Editor, is currently an NHMRC funded Principal Research Fellow, Head of the Immunology Division and of the Immunology & Immunodefi ciency lab at the Garvan Institute of Medical Research. Since 1995, he has published >115 peer-reviewed research articles and invited reviews and has been funded by research fellowships and grants awarded by the NHMRC, Cancer Council NSW, XLP Research Trust and Association for International Cancer Research. In 2011, he received the Gottschalk Medal from the Australian Academy of Sciences, which recognises outstanding research in the medical sciences by scientists no more than 40 years of age. His research interests focus on the biology of human lymphocytes in health and disease, and elucidating mechanisms whereby defects in Gabrielle Belz signaling, activation and function underlie the Ian Parish development and clinical features of several Gabrielle Belz, Editor-in-Chief, is currently immunodefi ciencies. He is also a Section Ian Parish, News and Commentary Editor, an ARC Future Fellow and Elizabeth Editor for the Journal of Immunology, an currently drives a research group at the Blackburn NHMRC Fellowship recipient. Associate Editor for the Journal of Clinical John Curtin School of Medical Research at She has a central interest in the formation of Immunology, and an Advisory Editor for the the Australian National University having protective immune responses in response to Journal of Experimental Medicine.