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2020 Annual Report PHOTOGRAPH CREDITS: Pp Response and Recovery 2020 Annual Report PHOTOGRAPH CREDITS: pp. 13/18/back cover, Brett Summerell; p. 19, CDC/Alissa Eckert, MSMI; Dan Higgins, MAMS. Contents Chairman’s 2019/2020 Bioplatforms report Highlights Australia 2 4 5 Bioplatforms Bioplatforms Feature network activities stories 6 7 8 Network National Collaboration LEADERSHIP access Initiatives and partnerships Bioplatforms Australia is committed to maintaining a high standard of governance and leadership. Strategic direction and operational oversight is provided by an independent Board of Directors and supported by an Executive Management Committee who advise on platform technologies and organisational initiatives. Board Members and Responsibilities Executive Management Committee 10 13 16 Bioplatforms Australia’s Directors offer a wealth of experience The Executive Management Committee manages and advises across scientific, business and government domains. on platform issues and operations. It is also responsible for Industry Capabilities BioCommons Each Director has responsibility for particular aspects of implementing strategic initiatives, including Commonwealth engagement network organisational strategy in addition to their fiduciary duties. funding agreements established with network partners. Dr Leslie Trudzik – Chairman Committee members are: Les is a founding Board Member of Bioplatforms Australia and Chair became Chairman in 2013. He is responsible for developing the Andrew Gilbert, Chief Executive, Bioplatforms Australia organisation’s performance and impact framework. Genomics Convenor Dr Sue Meek – Director Professor Marc Wilkins Sue joined the Board in 2012 and is responsible for organisational communications and liaison with the Proteomics Convenor 20 24 Commonwealth government. Professor Ian Smith 18 Dr Katherine Woodthorpe – Director Metabolomics Convenor Katherine joined the Board in 2014 and is responsible for Professor Malcolm McConville industry engagement, advising on the innovation pipeline, and Bioinformatics Convenor providing experience to support challenging decision-making Associate Professor Andrew Lonie processes. Professor Peter Gray - Director Peter was appointed to the Board to provide scientific insight and expertise to all platforms. He supports academic and industry engagement, and integration with aligned NCRIS capabilities. 1 Chairman’s Review The last year has been like no other, with Australia in particular facing a succession of challenges related to drought, bushfire and the global pandemic. These have caused intense strain on individuals, families, communities and the nation at large. Our thoughts remain with those affected, and we are pleased to have had the opportunity to play some small part in focussing our actions on responses to, and mitigation of, the challenges. Scientific disciplines and our nation’s We thank our network of NCRIS facilities Notwithstanding that it has been an scientists have come to the fore, who have persisted, and in some cases extraordinarily difficult year that has providing objective analysis and re-oriented, through difficult circumstances demanded significant attention over and advice on pressing issues. Moreover, to deliver access to critical services in above normal operations, the national there appears to be growing genomics, proteomics, metabolomics Bioplatforms team has made great acknowledgement of the important role and bioinformatics. They have supported progress on all fronts of our strategy. The Bioplatforms Australia Melanoma We thank our of science and scientific advice, and that vital research agendas such as: We have now implemented all new Genome Project, which was initiated in investment in science is a critical national funding arrangements in response to the “ • investigation of traits in native plants 2012 and whose findings were published network of NCRIS resource in leading the mitigation and 2018 budget contribution to our NCRIS that will provide solutions to drought in Nature in 2017, was again analysed recovery from devastating drought, program, including the establishment of facilities who tolerance in agriculture and food in the context of an international bushfires and COVID-19. two new facilities in South Australia and security. Australia’s native flora has an “Pan-cancer analysis of whole genomes” Western Australia. have persisted, One critical way the scientific amazing tolerance and adaptability to investigating molecular dysfunction community has responded is through a range of stresses and we are aiming The South Australian Genomics across cancer families. This second study and in some cases the deployment of national capability to to harness this plasticity in future Consortium (SAGC) is a newly formed was also published in Nature in February support the current acute circumstances. agricultural development. cooperative of genomics facilities and 2020 and is indicative of the strategic re-oriented, Also important will be the role that will users in South Australia, forming a approach that has been established for • development of genetic analyses to be needed in consolidating hard gained consolidated capacity and staff aimed at developing critical data resources for through difficult support breeding programs for lessons and knowledge into planning providing South Australian researchers use and re-use. Australia’s most threatened species, circumstances. for future events, and to support the with a broader and deeper genomic acutely brought to the nation’s attention In reporting the above achievements, rebuilding of the economy with new resource. Connected into national with the devastation caused to our I would like to acknowledge my fellow services, products, businesses and capacities through the Australian wildlife through the Bushfire crisis. Directors, Professor Sue Meek, Dr jobs. There is much that can be done Genome Research Facility (AGRF), the Katherine Woodthorpe and Professor to position Australia for greater self- • support for the development of SAGC will focus on local needs for Peter Gray, all of whom have provided Professor Ian Smith (Proteomics), reliance in light of the needs revealed a crucial vaccine for COVID-19 by biomedical research and plant science flexible and adaptive leadership of Professor Malcolm McConville during the current pandemic. the CEPI team at The University of with sites at the South Australian Health Bioplatforms over the past year. (Metabolomics) and Associate Professor Queensland Australian Institute for and Medical Research Institute (SAHMRI) Research Infrastructures as collective Andrew Lonie (Bioinformatics). All have Bioengineering and Nanotechnology. and the Waite Campus respectively. The Bioplatforms team, led by our national assets have been ready led the growth and development of our This work was not only in response Chief Executive Andrew Gilbert, also and well positioned to respond to Genomics Western Australia has national networks with great energy, to the current pandemic but builds continue to deliver high quality ideas emergency needs over the year. The also been formed, combining key spirit and direction. Dr Les Trudzik critical capacity to contribute to and outcomes and have performed ongoing investment in and operation of participants in Perth and consolidating future concerns. Pleasingly, this work beyond expectations in this difficult I look forward to ongoing interaction Chair NCRIS has ensured that leading-edge access to significant state-based has been driven together with our year of isolation, adjusting rapidly and with the Bioplatforms Australia network instrumentation, staffed with expert capacities, including recently acquired NCRIS peer – Therapeutic Innovation seamlessly to new ways of working in the coming year, and to ensure scientists and operating with a culture Illumina NovaSeq and PacBio Sequel Australia. themselves, as well as with those of the that NCRIS investment in research of collaboration and service, has been II instrumentation. This consolidated broader Bioplatforms network. infrastructure continues to best meet available when, where and as needed. consortium will enhance the ability of both the immediate and longer-term In relation to these facilities, it is important WA researchers to collaborate readily needs of the life sciences. with research teams from elsewhere in to recognise the critical role provided the country. by Bioplatforms’ scientific leadership – Professor Marc Wilkins (Genomics), 2 3 HIGHLIGHTS 2019-20 Bioplatforms Australia Bioplatforms Australia is a national asset that supports Life Science innovation by connecting investment and researchers with leading ‘omics research capabilities and bioinformatics Our mission is to enhance Australian genomics, proteomics, metabolomics and bioinformatics research capabilities, to support innovation and help transform scientific outcomes into tangible benefits for Australians. We do this by: Capability Initiatives and collaborations • Supporting strategic national investments in scientific research infrastructure and personnel; • Enhancing Accessibility of the national infrastructure to enable Australian research; 15 world-class facilities 12 active National initiatives • Maximising Quality of research via international best practice; • Identifying and supporting Impact to ensure socio-economic return; $18.7 million invested in best Partner Organisation to • Maximising Collaboration in delivery and usage of the national infrastructure; and of breed technology and 5 ARC Centres of Excellence • Acting as a Catalyst
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