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Deep Neck Infections 55
Deep Neck Infections 55 Behrad B. Aynehchi Gady Har-El Deep neck space infections (DNSIs) are a relatively penetrating trauma, surgical instrument trauma, spread infrequent entity in the postpenicillin era. Their occur- from superfi cial infections, necrotic malignant nodes, rence, however, poses considerable challenges in diagnosis mastoiditis with resultant Bezold abscess, and unknown and treatment and they may result in potentially serious causes (3–5). In inner cities, where intravenous drug or even fatal complications in the absence of timely rec- abuse (IVDA) is more common, there is a higher preva- ognition. The advent of antibiotics has led to a continu- lence of infections of the jugular vein and carotid sheath ing evolution in etiology, presentation, clinical course, and from contaminated needles (6–8). The emerging practice antimicrobial resistance patterns. These trends combined of “shotgunning” crack cocaine has been associated with with the complex anatomy of the head and neck under- retropharyngeal abscesses as well (9). These purulent col- score the importance of clinical suspicion and thorough lections from direct inoculation, however, seem to have a diagnostic evaluation. Proper management of a recog- more benign clinical course compared to those spreading nized DNSI begins with securing the airway. Despite recent from infl amed tissue (10). Congenital anomalies includ- advances in imaging and conservative medical manage- ing thyroglossal duct cysts and branchial cleft anomalies ment, surgical drainage remains a mainstay in the treat- must also be considered, particularly in cases where no ment in many cases. apparent source can be readily identifi ed. Regardless of the etiology, infection and infl ammation can spread through- Q1 ETIOLOGY out the various regions via arteries, veins, lymphatics, or direct extension along fascial planes. -
Tenderness Over the Hyoid Bone Can Indicate Epiglottitis in Adults
J Am Board Fam Med: first published as 10.3122/jabfm.19.5.517 on 1 September 2006. Downloaded from Tenderness Over the Hyoid Bone Can Indicate Epiglottitis in Adults Hiroshi Ehara, MD Adult acute epiglottitis is a rare but life-threatening disease caused by obstruction of the airway. The symptoms and signs of this disease may be nonspecific without apparent airway compromise. We en- countered 3 consecutive cases of adult patients with this disease in a single 5-month period in one phy- sician’s office. In all cases, physical examination revealed tenderness of the anterior neck over the hyoid bone. These observations assisted us in identifying this rare disease quickly. We suggest that tenderness over the hyoid bone should raise suspicion of adult acute epiglottitis. (J Am Board Fam Med 2006;19: 517–20.) Adult acute epiglottitis is an inflammatory disease power, and talking aggravated her sore throat. At of the epiglottis and adjacent structures resulting admission, the patient did not seem to be critically from infection. It can be a rapidly fatal condition ill. Her voice was neither muffled nor hoarse. The because of the potential for sudden upper airway vital signs indicating the nature of her condition obstruction. Early recognition of acute epiglottitis were as follows: body temperature, 37.0°C (axil- is therefore of the utmost importance in minimiz- lary); blood pressure, 90/64 mm Hg; pulse, 64/min; ing morbidity and mortality. respirations, 24/min; peripheral oxygen saturation, Unfortunately, misdiagnosis occurs in 23% to 97%. At this point, these findings were not suffi- 1–3 31% of the cases of adult acute epiglottitis. -
Parts of the Body 1) Head – Caput, Capitus 2) Skull- Cranium Cephalic- Toward the Skull Caudal- Toward the Tail Rostral- Toward the Nose 3) Collum (Pl
BIO 3330 Advanced Human Cadaver Anatomy Instructor: Dr. Jeff Simpson Department of Biology Metropolitan State College of Denver 1 PARTS OF THE BODY 1) HEAD – CAPUT, CAPITUS 2) SKULL- CRANIUM CEPHALIC- TOWARD THE SKULL CAUDAL- TOWARD THE TAIL ROSTRAL- TOWARD THE NOSE 3) COLLUM (PL. COLLI), CERVIX 4) TRUNK- THORAX, CHEST 5) ABDOMEN- AREA BETWEEN THE DIAPHRAGM AND THE HIP BONES 6) PELVIS- AREA BETWEEN OS COXAS EXTREMITIES -UPPER 1) SHOULDER GIRDLE - SCAPULA, CLAVICLE 2) BRACHIUM - ARM 3) ANTEBRACHIUM -FOREARM 4) CUBITAL FOSSA 6) METACARPALS 7) PHALANGES 2 Lower Extremities Pelvis Os Coxae (2) Inominant Bones Sacrum Coccyx Terms of Position and Direction Anatomical Position Body Erect, head, eyes and toes facing forward. Limbs at side, palms facing forward Anterior-ventral Posterior-dorsal Superficial Deep Internal/external Vertical & horizontal- refer to the body in the standing position Lateral/ medial Superior/inferior Ipsilateral Contralateral Planes of the Body Median-cuts the body into left and right halves Sagittal- parallel to median Frontal (Coronal)- divides the body into front and back halves 3 Horizontal(transverse)- cuts the body into upper and lower portions Positions of the Body Proximal Distal Limbs Radial Ulnar Tibial Fibular Foot Dorsum Plantar Hallicus HAND Dorsum- back of hand Palmar (volar)- palm side Pollicus Index finger Middle finger Ring finger Pinky finger TERMS OF MOVEMENT 1) FLEXION: DECREASE ANGLE BETWEEN TWO BONES OF A JOINT 2) EXTENSION: INCREASE ANGLE BETWEEN TWO BONES OF A JOINT 3) ADDUCTION: TOWARDS MIDLINE -
Sesamoid Bone in the Tendon of the Supinator Muscle of Dogs: Incidence and Comparison of Radiographic and Computed Tomographic Features
Sesamoid bone in the tendon of the supinator muscle of dogs: incidence and comparison of radiographic and computed tomographic features Word count: 8473 Manon Dorny Student number: 01609678 Supervisor: Dr. Ingrid Gielen Supervisor: Prof. dr. Wim Van Den Broeck Supervisor: Dr. Aquilino Villamonte Chevalier A dissertation submitted to Ghent University in partial fulfilment of the requirements for the degree of Master of Veterinary Medicine Academic year: 2018 - 2019 Ghent University, its employees and/or students, give no warranty that the information provided in this thesis is accurate or exhaustive, nor that the content of this thesis will not constitute or result in any infringement of third-party rights. Ghent University, its employees and/or students do not accept any liability or responsibility for any use which may be made of the content or information given in the thesis, nor for any reliance which may be placed on any advice or information provided in this thesis. ACKNOWLEDGEMENTS I would like to thank the people that helped me accomplish this thesis and helped me achieve my degree in veterinary science. First of all I would like to thank Dr. Ingrid Gielen, Dr. Aquilino Villamonte Chevalier and Prof. Dr. Wim Van Den Broeck. I thank them all for their time spend in helping me with my research, their useful advice and their endless patience. Without their help, I wouldn’t have been able to accomplish this thesis. Next I would like to thank my family and friends for their continuing support and motivation during the last years of vet school. My parents and partner especially, for all the mental breakdowns they had to endure in periods of exams and deadlines. -
On the Development of Sesamoid Bones
bioRxiv preprint doi: https://doi.org/10.1101/316901; this version posted May 8, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. On the Development of Sesamoid Bones Shai Eyal1*, Sarah Rubin1, Sharon Krief1, Lihi Levin1 and Elazar Zelzer1 1 Weizmann Institute of Science, Department of Molecular Genetics, PO Box 26, Rehovot 76100, Israel * Current address: University of California at San Diego, Department of Cellular and Molecular Medicine, La Jolla, CA 92093, USA Corresponding author: [email protected] Keywords: Sesamoid bone, Patella, Fabella, Digits, Sox9, Scleraxis, Tgfβ, Bmp2, Bmp4, Joint, Mouse bioRxiv preprint doi: https://doi.org/10.1101/316901; this version posted May 8, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. ABSTRACT Sesamoid bones are a special group of small auxiliary bones that form in proximity to joints and contribute to their stability and function. Sesamoid bones display high degree of variability in size, location, penetrance and anatomical connection to the main skeleton across vertebrate species. Therefore, providing a comprehensive developmental model or classification system for sesamoid bones is challenging. Here, we examine the developmental mechanisms of three anatomically different sesamoid bones, namely patella, lateral fabella and digit sesamoids. Through a comprehensive comparative analysis at the cellular, molecular and mechanical levels, we demonstrate that all three types of sesamoid bones originated from Sox9+/Scx+ progenitors under the regulation of TGFβ and independent of mechanical stimuli from muscles. -
The Effects of Non-Surgical Interventions on Osteoarthritis-Like Changes in the Mouse Knee" (2008)
University of South Florida Scholar Commons Graduate Theses and Dissertations Graduate School 3-31-2008 The ffecE ts of Non-Surgical Interventions on Osteoarthritis-Like Changes in the Mouse Knee Wendy K. Anemaet University of South Florida Follow this and additional works at: https://scholarcommons.usf.edu/etd Part of the American Studies Commons Scholar Commons Citation Anemaet, Wendy K., "The Effects of Non-Surgical Interventions on Osteoarthritis-Like Changes in the Mouse Knee" (2008). Graduate Theses and Dissertations. https://scholarcommons.usf.edu/etd/121 This Dissertation is brought to you for free and open access by the Graduate School at Scholar Commons. It has been accepted for inclusion in Graduate Theses and Dissertations by an authorized administrator of Scholar Commons. For more information, please contact [email protected]. The Effects of Non-Surgical Interventions on Osteoarthritis-Like Changes in the Mouse Knee by Wendy K. Anemaet A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy School of Aging Studies College of Arts and Sciences University of South Florida Co-Major Professor: Anna Plaas, Ph.D. Co-Major Professor: William Haley, Ph.D. Katalin Mikecz, Ph.D. Keiba Shaw, Ed.D. Brent Small, Ph.D. Date of Approval: March 31, 2008 Keywords: cartilage, degradation, exercise, hyaluronan, transforming growth factor-beta, treadmill © Copyright 2008, Wendy K. Anemaet Dedication I dedicate this to my daughter, Aviendha, who has been right there every step of the way. You have experienced and endured more than most 10 year olds in this process. My hope is that it inspires (not disheartens) you to continually ask questions and seek answers. -
Sesamoid Bone of the Medial Collateral Ligament of the Knee Joint
CASE REPORT Eur. J. Anat. 21 (4): 309-313 (2017) Sesamoid bone of the medial collateral ligament of the knee joint Omar M. Albtoush, Konstantin Nikolaou, Mike Notohamiprodjo Department of Diagnostic and Interventional Radiology, Karls Eberhard Universität Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany SUMMARY tomical relations and the exclusion of other possi- bilities. The variable occurrence of the sesamoid bones This article supports the theory stating that the supports the theory stating that the development development and evolution of the sesamoid bones and evolution of these bones are controlled are controlled through the interaction between in- through the interaction between intrinsic genetic trinsic genetic factors and extrinsic epigenetic stim- factors and extrinsic stimuli. In the present article uli, which can explain their variable occurrence. we report a sesamoid bone at the medial collateral ligament of the knee joint, a newly discovered find- CASE REPORT ing in human and veterinary medicine. We present a case of a 51-year-old female pa- Key words: Sesamoid – MCL – Knee – Fabella – tient, who presented with mild pain at the medial Cyamella aspect of the left knee. No trauma has been re- ported. An unenhanced spiral CT-Scan was per- INTRODUCTION formed with 2 mm thickness, 120 kvp and 100 mAs, which showed preserved articulation of the New structural anatomical discoveries are not so knee joint with neither joint effusion, nor narrowing often encountered. However, their potential occur- of the joint space nor articulating cortical irregulari- rence should be kept in mind, which can eventually ties (Fig. 1). Mild subchondral sclerosis was de- help in a better understanding of patients’ symp- picted at the medial tibial plateau as a sign of early toms and subsequently improve the management osteoarthritis. -
The Axial Skeleton – Hyoid Bone
Marieb’s Human Anatomy and Physiology Ninth Edition Marieb Hoehn Chapter 7 The Axial and Appendicular Skeleton Lecture 14 1 Lecture Overview • Axial Skeleton – Hyoid bone – Bones of the orbit – Paranasal sinuses – Infantile skull – Vertebral column • Curves • Intervertebral disks –Ribs 2 The Axial Skeleton – Hyoid Bone Figure from: Saladin, Anatomy & Physiology, McGraw Hill, 2007 Suspended from the styloid processes of the temporal bones by ligaments and muscles The hyoid bone supports the larynx and is the site of attachment for the muscles of the larynx, pharynx, and tongue 3 1 Axial Skeleton – the Orbit See Fig. 7.6.1 in Martini and Fig. 7.20 in Figure: Martini, Right Hole’s Textbook Anatomy & Physiology, Optic canal – Optic nerve; Prentice Hall, 2001 opthalmic artery Superior orbital fissure – Oculomotor nerve, trochlear nerve, opthalmic branch of trigeminal nerve, abducens nerve; opthalmic vein F Inferior orbital fissure – Maxillary branch of trigeminal nerve E Z S L Infraorbital groove – M N Infraorbital nerve, maxillary branch of trigeminal nerve, M infraorbital artery Lacrimal sulcus – Lacrimal sac and tearduct *Be able to label a diagram of the orbit for lecture exam 4 Nasal Cavities and Sinuses Paranasal sinuses are air-filled, Figure: Martini, mucous membrane-lined Anatomy & Physiology, chambers connected to the nasal Prentice Hall, 2001 cavity. Superior wall of nasal cavities is formed by frontal, ethmoid, and sphenoid bones Lateral wall of nasal cavities formed by maxillary and lacrimal bones and the conchae Functions of conchae are to create swirls, turbulence, and eddies that: - direct particles against mucus - slow air movement so it can be warmed and humidified - direct air to superior nasal cavity to olfactory receptors 5 Axial Skeleton - Sinuses Sinuses are lined with mucus membranes. -
View of Long Bone Structural Features
APPLICATIONS OF HUMAN BONE MATERIALS AND SYNTHESIZED BIOMATERIALS FOR BONE-RELATED TISSUE ENGINEERING A Dissertation Presented to The Graduate Faculty of The University of Akron In Partial Fulfillment Of the requirements for the Degree Doctor of Philosophy Qing Yu December, 2016 APPLICATIONS OF HUMAN BONE MATERIALS AND SYNTHESIZED BIOMATERIALS FOR BONE-RELATED TISSUE ENGINEERING Qing Yu Dissertation Approved: Accepted: ______________________________ ______________________________ Advisor Department Chair Dr. William J. Landis Dr. Coleen Pugh ______________________________ ______________________________ Committee Member Dean of the College Dr. Nita Sahai Dr. Eric J. Amis ______________________________ ______________________________ Committee Member Dean of the Graduate School Dr. Coleen Pugh Dr. Chand Midha ______________________________ ______________________________ Committee Member Date Dr. Marnie Saunders ______________________________ Committee Member Dr. Ge Zhang ii ABSTRACT Engineered bone grafting has been considered as one of the alternative methods for bone regeneration in both fundamental research and clinical applications to address bone disorders. Bone graft materials, autologous bone, allogeneic bone and synthetic polymer scaffolds have been commonly utilized surgically as substrates for bone grafting. In this dissertation, periosteum, a thin membrane in which progenitor cells can develop into osteoblasts to regenerate bone tissue, has been applied in three different studies to determine its capability to induce new bone formation. In the first study, human periosteum-wrapped bone allografts were implanted subcutaneously in athymic mice followed by sample harvest and gene expression analysis and histological assessment. The second study developed a tissue-engineering approach to generate a functional tendon-to-bone enthesis. In this instance, the constructs were fabricated from human periosteum-wrapped allograft bone and tenocyte- and chondrocyte-seeded biomaterials. -
Hyoid Bone Fusion and Bone Density Across the Lifespan: Prediction of Age and Sex
Hyoid bone fusion and bone density across the lifespan: prediction of age and sex Ellie Fisher, Diane Austin, Helen M. Werner, Ying Ji Chuang, Edward Bersu & Houri K. Vorperian Forensic Science, Medicine, and Pathology ISSN 1547-769X Forensic Sci Med Pathol DOI 10.1007/s12024-016-9769-x 1 23 Your article is published under the Creative Commons Attribution license which allows users to read, copy, distribute and make derivative works, as long as the author of the original work is cited. You may self- archive this article on your own website, an institutional repository or funder’s repository and make it publicly available immediately. 1 23 Forensic Sci Med Pathol DOI 10.1007/s12024-016-9769-x ORIGINAL ARTICLE Hyoid bone fusion and bone density across the lifespan: prediction of age and sex 1 1 1 1 Ellie Fisher • Diane Austin • Helen M. Werner • Ying Ji Chuang • 2 1 Edward Bersu • Houri K. Vorperian Accepted: 7 March 2016 Ó The Author(s) 2016. This article is published with open access at Springerlink.com Abstract The hyoid bone supports the important func- predictors of age group for adult females. This study pro- tions of swallowing and speech. At birth, the hyoid bone vides a developmental baseline for understanding hyoid consists of a central body and pairs of right and left lesser bone fusion and bone density in typically developing and greater cornua. Fusion of the greater cornua with the individuals. Findings have implications for the disciplines body normally occurs in adulthood, but may not occur at of forensics, anatomy, speech pathology, and anthropology. -
Hole's Human Anatomy and Physiology
Hole’s Human Anatomy and Physiology 1 Chapter 7 Skeletal System Bone Classification • Long Bones • Short Bones • Flat Bones • Irregular Bones • Sesamoid (Round) Bones 2 Parts of a Long Bone • epiphysis • distal • proximal • diaphysis • compact bone • spongy bone • articular cartilage • periosteum • endosteum • medullary cavity • trabeculae • marrow • red • yellow 3 Compact and Spongy Bone 4 Microscopic Structure of Compact Bone • osteon • central canal • perforating canal • osteocyte • lacuna • bone matrix • canaliculus 5 Bone Development Intramembranous Ossification • bones originate within sheetlike layers of connective tissues • broad, flat bones • skull bones (except mandible) • intramembranous bones Endochondral Ossification • bones begin as hyaline cartilage • form models for future bones • most bones of the skeleton • endochondral bones 6 Endochondral Ossification • hyaline cartilage model • epiphyseal plate • primary ossification center • osteoblasts vs. osteoclasts • secondary ossification centers 7 Growth at the Epiphyseal Plate First layer of cells • closest to the end of epiphysis • resting cells • anchors epiphyseal plate to epiphysis Second layer of cells • many rows of young cells • undergoing mitosis 8 Growth at the Epiphyseal Plate Third layer of cells • older cells • left behind when new cells appear • cells enlarging and becoming calcified Fourth layer of cells • thin • dead cells • calcified extracellular matrix 9 Homeostasis of Bone Tissue •Bone Resorption – action of osteoclasts and parathyroid hormone •Bone Deposition -
Suprahyoid and Infrahyoid Neck Overview
Suprahyoid and Infrahyoid Neck Overview Imaging Approaches & Indications by space, the skull base interactions above and IHN extension below are apparent. Neither CT nor MR is a perfect modality for imaging the • PPS has bland triangular skull base abutment without extracranial H&N. MR is most useful in the suprahyoid neck critical foramen involved; it empties inferiorly into (SHN) because it is less affected by oral cavity dental amalgam submandibular space (SMS) artifact. The SHN tissue is less affected by motion compared • PMS touches posterior basisphenoid and anterior with the infrahyoid neck (IHN); therefore, the MR image basiocciput, including foramen lacerum; PMS includes quality is not degraded by movement seen in the IHN. Axial nasopharyngeal, oropharyngeal, and hypopharyngeal and coronal T1 fat-saturated enhanced MR is superior to CECT mucosal surfaces in defining soft tissue extent of tumor, perineural tumor • MS superior skull base interaction includes zygomatic spread, and dural/intracranial spread. When MR is combined with CT of the facial bones and skull base, a clinician can obtain arch, condylar fossa, skull base, including foramen ovale (CNV3), and foramen spinosum (middle meningeal precise mapping of SHN lesions. Suprahyoid and Infrahyoid Neck artery); MS ends at inferior surface of body of mandible CECT is the modality of choice when IHN and mediastinum are • PS abuts floor of external auditory canal, mastoid tip, imaged. Swallowing, coughing, and breathing makes this area including stylomastoid foramen (CNVII); parotid tail a "moving target" for the imager. MR image quality is often extends inferiorly into posterior SMS degraded as a result. Multislice CT with multiplanar • CS meets jugular foramen (CNIX-XI) floor, hypoglossal reformations now permits exquisite images of the IHN canal (CNXII), and petrous internal carotid artery canal; unaffected by movement.