2015 AACA Annual Meeting Program

Total Page:16

File Type:pdf, Size:1020Kb

2015 AACA Annual Meeting Program June 9 – 12, 2015 | Henderson, Nevada President’s Report June 9-12, 2015 Green Valley Ranch Resort & Casino Henderson, NV Another year has quickly passed and I have been asked to summarize achievements/threats to the Association for our meeting program booklet. Much of this will be recanted in my introductory message on the opening day of the meeting in Henderson. As President, I am representing Council in recognizing the work of those individuals not already recognized in our standing committee reports that you will find in this program. One of our most active ad hoc committees has been the one looking into creating an endowment for the association through member and vendor sponsorships. Our past president, Anne Agur, has chaired this committee and deserves accolades for having the committee work hard and produce the materials you have either already seen, or will be introduced to in Henderson. The format was based on that used by many clinical organizations. It allows support at many different levels, the financial income from which is being invested for student awards and travel stipends. Our ambitious 5 year goal is $100,000. I hope that you will join me in thinking seriously about supporting this initiative - at whichever level you feel comfortable with. Every dollar goes to the endowment. In October, Council ratified the creation of our new standing committee - Brand Promotion and Outreach. This committee was formed by fusing the two ad hoc committees struck by Anne Agur when she was President. Last year our new branding was highly visible in Orlando and we want to use this momentum to continue raising the profile of the Association at many different types of events within and outside North America. Our regional meeting initiative has also taken off with the first one to be held in Salt Lake City this coming October. We encourage those within the region - and also those outside the region - to make an effort to attend this new meeting format. Our continuation and expansion of these regional meetings will depend on member support. Check this program, or our web site, for full information on this meeting being organized by Jon Wisco and associates locally. Association finances continue to hold solid. Much of this is due to an increased number of paying members coupled with the Wiley subscription deal and Shane Tubbs’ ability to run the editorial office within the budget provided by the Wiley Contract. This allows us to retain the Clinical Anatomy royalties provided by Wiley that continue to grow in size - this year close to $70,000. Our relationship with ASG (our association management group) continues to mature into a solid working relationship where we have a mutual understanding of what we need and want as an association. Both Caitlin and Shanan continue to do an outstanding job as the “face” of the association and our members speak highly of their interaction with the management team. In light of projected increased hourly charges over the next few years, and to ensure we retain a sound financial footing with ASG, I have asked our Financial Affairs Committee to work closely with them over the next 12 months to see where the majority of ASG services are utilized - which committees/aspects of the association run the largest hours of usage with ASG. We value ASG as our management colleagues and will work with them to ensure fiscal responsibility as the cost of doing business rises. Financial responsibility has been my greatest area of focus since entering the presidential stream of the AACA and I remain committed to seeing our well- crafted ASG-AACA relationship continue into the future. Finally, I want to ensure that each of you recognize the hard work of our Program Secretary (Noelle Granger), our meeting managers (David Porta and Sherry Downie) and the other members of the MOPP Committee for their efforts in creating this non-hosted meeting in Henderson. Our bid to hold the meeting jointly with AMI in San Antonio fell through at a date that was too late to get other sites involved. Las Vegas has an infinite number of meeting sites and Green Valley Ranch came through with a proposal that we felt welcomed us back after our Touro-sponsored 2007 meeting. We appreciate everyone’s effort to make this a meeting that differs only slightly from our typical hosted meetings. We are all looking forward to hearing from our Presidential speaker - Francine Netter; Carol Scott-Conner, our Honored Member, and remembering our Adkins Award winner, Larry Ross. I look forward to seeing you all during the meeting and I encourage anyone with Association-related issues or ideas to discuss them with me at any time. Brian R. MacPherson, Ph.D. page 1 Table of Contents Floorplan of Convention Center .................................................................................................3 Block Schedule of Events ..........................................................................................................4 Handy Tear-Out Sheet............................................................................................................3,4 Acknowledgement and Thanks to our Sponsors and Exhibitors ................................................5 Information on Food/Beverage Around Green Valley Ranch .....................................................8 Pre-Meeting Events ...................................................................................................................9 Scientific Program .....................................................................................................................9 Presidential Speaker – Francine Mary Netter ..........................................................................14 Honored Member –Carol Scott-Conner ..................................................................................15 Distinguished Service Award – Lawrence M. Ross .................................................................16 Career Development Committee Symposium ......................................................................... 17 “High Point in Anatomical Art” by Acland, Machado & Gielecki...............................................19 “Anatomy in the New Millennium” Lunch Symposium ..............................................................20 Clinical Anatomical Terminology Committee Symposium ........................................................22 Poster Listing Poster Session 1 - Head and Neck .............................................................................24 Poster Session 2 - Limbs ............................................................................................27 Poster Session 3 - Torso .............................................................................................30 Poster Session 4 - Anatomical Services & Education .................................................33 Annual Business Meeting Agenda ...........................................................................................36 Annual Business Meeting Minutes – Orlando ..........................................................................37 Officers of the AACA Council ..................................................................................................40 Clinical Anatomy – the Official Journal of AACA ..................................................................... 41 Committee Reports Anatomical Services Committee .................................................................................42 Career Development Committee.................................................................................43 Clinical Anatomical Terminology Committee ...............................................................44 Educational Affairs Committee ...................................................................................45 Journal Committee......................................................................................................46 Meeting Oversight and Program Planning Committee ................................................47 Membership Committee ..............................................................................................49 Nominating Committee ...............................................................................................50 2015 Annual Meeting Committee ................................................................................ 51 Listserv Admin Report ................................................................................................52 Abstract Listing by Author Platform Presentations ...............................................................................................53 TechFair Presentations ...............................................................................................63 Poster Presentations...................................................................................................65 William Carey University College of Osteopathic Medicine Advertisement ...........................122 page 2 ground levelGVR map Conference Center Floor Plan shuttle schedule THE DISTRICT “STRIP” TRANSPORTATION GREEN VALLEY RANCH RESORT TO Ground Level MANDALAY BAY HOTEL ARCADE & The shuttle departs from CINEMAS the GVR Hotel Valet. 215 PARKING PASEO 12:00PM 2:00PM GARAGE VERDE 4:00PM 8:00PM MANDALAY BAY HOTEL TO GREEN VALLEY RANCH RESORT CASINO The shuttle picks up at the Tour & Travel VALET Lobby located on the lower level. 12:30PM 2:30PM EAST TOWER 4:30PM 8:30PM GUEST ELEVATOR EAST HOTEL TOWER GRAND EVENTS EL VIENTO AIRPORT TRANSPORTATION
Recommended publications
  • 3 Embryology and Development
    BIOL 6505 − INTRODUCTION TO FETAL MEDICINE 3. EMBRYOLOGY AND DEVELOPMENT Arlet G. Kurkchubasche, M.D. INTRODUCTION Embryology – the field of study that pertains to the developing organism/human Basic embryology –usually taught in the chronologic sequence of events. These events are the basis for understanding the congenital anomalies that we encounter in the fetus, and help explain the relationships to other organ system concerns. Below is a synopsis of some of the critical steps in embryogenesis from the anatomic rather than molecular basis. These concepts will be more intuitive and evident in conjunction with diagrams and animated sequences. This text is a synopsis of material provided in Langman’s Medical Embryology, 9th ed. First week – ovulation to fertilization to implantation Fertilization restores 1) the diploid number of chromosomes, 2) determines the chromosomal sex and 3) initiates cleavage. Cleavage of the fertilized ovum results in mitotic divisions generating blastomeres that form a 16-cell morula. The dense morula develops a central cavity and now forms the blastocyst, which restructures into 2 components. The inner cell mass forms the embryoblast and outer cell mass the trophoblast. Consequences for fetal management: Variances in cleavage, i.e. splitting of the zygote at various stages/locations - leads to monozygotic twinning with various relationships of the fetal membranes. Cleavage at later weeks will lead to conjoined twinning. Second week: the week of twos – marked by bilaminar germ disc formation. Commences with blastocyst partially embedded in endometrial stroma Trophoblast forms – 1) cytotrophoblast – mitotic cells that coalesce to form 2) syncytiotrophoblast – erodes into maternal tissues, forms lacunae which are critical to development of the uteroplacental circulation.
    [Show full text]
  • Te2, Part Iii
    TERMINOLOGIA EMBRYOLOGICA Second Edition International Embryological Terminology FIPAT The Federative International Programme for Anatomical Terminology A programme of the International Federation of Associations of Anatomists (IFAA) TE2, PART III Contents Caput V: Organogenesis Chapter 5: Organogenesis (continued) Systema respiratorium Respiratory system Systema urinarium Urinary system Systemata genitalia Genital systems Coeloma Coelom Glandulae endocrinae Endocrine glands Systema cardiovasculare Cardiovascular system Systema lymphoideum Lymphoid system Bibliographic Reference Citation: FIPAT. Terminologia Embryologica. 2nd ed. FIPAT.library.dal.ca. Federative International Programme for Anatomical Terminology, February 2017 Published pending approval by the General Assembly at the next Congress of IFAA (2019) Creative Commons License: The publication of Terminologia Embryologica is under a Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) license The individual terms in this terminology are within the public domain. Statements about terms being part of this international standard terminology should use the above bibliographic reference to cite this terminology. The unaltered PDF files of this terminology may be freely copied and distributed by users. IFAA member societies are authorized to publish translations of this terminology. Authors of other works that might be considered derivative should write to the Chair of FIPAT for permission to publish a derivative work. Caput V: ORGANOGENESIS Chapter 5: ORGANOGENESIS
    [Show full text]
  • Understanding Entheseal Changes: Definition and Life Course Changes Sébastien Villotte, Christopher J
    Understanding Entheseal Changes: Definition and Life Course Changes Sébastien Villotte, Christopher J. Knüsel To cite this version: Sébastien Villotte, Christopher J. Knüsel. Understanding Entheseal Changes: Definition and Life Course Changes. International Journal of Osteoarchaeology, Wiley, 2013, Entheseal Changes and Occupation: Technical and Theoretical Advances and Their Applications, 23 (2), pp.135-146. 10.1002/oa.2289. hal-03147090 HAL Id: hal-03147090 https://hal.archives-ouvertes.fr/hal-03147090 Submitted on 19 Feb 2021 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. International Journal of Osteoarchaeology Understanding Entheseal Changes: Definition and Life Course Changes Journal: International Journal of Osteoarchaeology Manuscript ID: OA-12-0089.R1 Wiley - ManuscriptFor type: Commentary Peer Review Date Submitted by the Author: n/a Complete List of Authors: Villotte, Sébastien; University of Bradford, AGES Knusel, Chris; University of Exeter, Department of Archaeology entheses, enthesopathy, Musculoskeletal Stress Markers (MSM), Keywords: senescence, activity, hormones, animal models, clinical studies http://mc.manuscriptcentral.com/oa Page 1 of 27 International Journal of Osteoarchaeology 1 2 3 Title: 4 5 Understanding Entheseal Changes: Definition and Life Course Changes 6 7 8 Short title: 9 10 Understanding Entheseal Changes 11 12 13 Keywords: entheses; enthesopathy; Musculoskeletal Stress Markers (MSM); senescence; 14 15 activity; hormones; animal models; clinical studies 16 17 18 Authors: For Peer Review 19 20 Villotte S.
    [Show full text]
  • Laparoscopic Extraperitoneal Salpingo-Oophorectomy in Women with Suspicious Ovarian Mass, a Way to Reduce the Risk of Spillage
    5 Surgical Technique Page 1 of 5 Laparoscopic extraperitoneal salpingo-oophorectomy in women with suspicious ovarian mass, a way to reduce the risk of spillage Giulio Sozzi, Giulia Zaccaria, Mariano Catello Di Donna, Giuseppina Lo Balbo, Stefania Cannarozzo, Vito Chiantera Department of Gynecologic Oncology, University of Palermo, Piazza Nicola Leotta, Palermo, Italy Correspondence to: Giulio Sozzi, MD. Department of Gynecologic Oncology, University of Palermo, Piazza Nicola Leotta 4, 90127 Palermo, Italy. Email: [email protected]. Abstract: The objective of the present paper is to provide a step by step description of the laparoscopic extraperitoneal salpingo-oophorectomy, a surgical technique useful to reduce the risk of spillage in women with suspected ovarian masses. The patient was a 52-year-old woman with sonographic diagnosis of a multilocular, 5 cm lesion, with Color Score 3 at right ovary. Computed tomography (CT) scan excluded any other localization of disease. Tumor markers were negative, except for Ca 19.9 that was 85 IU/mL. Preliminary diagnostic laparoscopy was performed and peritoneal carcinomatosis was excluded. In order to obtain a histological diagnosis, an extraperitoneal right salpingo-oophorectomy was performed. At frozen section analysis it was diagnosed an ovarian adenocarcinoma. Therefore, a laparoscopic complete surgical staging including total hysterectomy, controlateral salpingo-oophorectomy, infracolic omentectomy, multiple peritoneal biopsies, and pelvic and para-aortic lymphadenectomy, was performed. Operative time was 240 minutes and estimated blood loss was about 50 mL. No intra or post-operative complications were observed, and the patient was discharged 3 days after surgery. Final histology showed the presence of clear cell high grade carcinoma in both ovaries without fallopian tubes infiltration.
    [Show full text]
  • Muscle Tissue
    10 Muscle Tissue PowerPoint® Lecture Presentations prepared by Jason LaPres Lone Star College—North Harris © 2012 Pearson Education, Inc. 10-1 An Introduction to Muscle Tissue • Learning Outcomes • 10-1 Specify the functions of skeletal muscle tissue. • 10-2 Describe the organization of muscle at the tissue level. • 10-3 Explain the characteristics of skeletal muscle fibers, and identify the structural components of a sarcomere. • 10-4 Identify the components of the neuromuscular junction, and summarize the events involved in the neural control of skeletal muscle contraction and relaxation. © 2012 Pearson Education, Inc. 10-1 An Introduction to Muscle Tissue • Learning Outcomes • 10-5 Describe the mechanism responsible for tension production in a muscle fiber, and compare the different types of muscle contraction. • 10-6 Describe the mechanisms by which muscle fibers obtain the energy to power contractions. • 10-7 Relate the types of muscle fibers to muscle performance, and distinguish between aerobic and anaerobic endurance. © 2012 Pearson Education, Inc. 10-1 An Introduction to Muscle Tissue • Learning Outcomes • 10-8 Identify the structural and functional differences between skeletal muscle fibers and cardiac muscle cells. • 10-9 Identify the structural and functional differences between skeletal muscle fibers and smooth muscle cells, and discuss the roles of smooth muscle tissue in systems throughout the body. © 2012 Pearson Education, Inc. An Introduction to Muscle Tissue • Muscle Tissue • A primary tissue type, divided into: • Skeletal muscle tissue • Cardiac muscle tissue • Smooth muscle tissue © 2012 Pearson Education, Inc. 10-1 Functions of Skeletal Muscle Tissue • Skeletal Muscles • Are attached to the skeletal system • Allow us to move • The muscular system • Includes only skeletal muscles © 2012 Pearson Education, Inc.
    [Show full text]
  • Research Review Fibrocartilage
    J. Anat. (1990), 171, pp. 1-15 1 Printed in Great Britain Research Review Fibrocartilage M. BENJAMIN AND E. J. EVANS Department of Anatomy, University of Wales College of Cardiff, PO Box 900, Cardif CF1 3 YF, Wales Fibrocartilage has long been a neglected tissue that is too often viewed as a poor relation of hyaline cartilage. It failed to achieve the status of a tissue with the early histologists, but it is beginning to come of age, for modem techniques are revealing some exciting secrets about fibrocartilage in knee joint menisci and intervertebral discs in particular. Yet there has never been any general review on fibrocartilage, and workers concerned with the tissue in one organ rarely consider it in another. Consequently, we lack any global picture that would encourage the spread of interest in the tissue and the effective exchange of ideas. Our review deals largely with the white fibrocartilage of standard texts and for reasons of space excludes yellow elastic cartilage. We have concentrated on fibrocartilage as a tissue rather than fibrocartilages as organs. HISTORICAL CONSIDERATIONS The most important work on cartilage in the older literature is that of Schaffer (1930). His monograph is a thorough, comparative account of cartilage and related tissues throughout the animal kingdom. The reader interested in fibrocartilage must also study Schaffer's account of chondroid tissue, for some tissues that would now be regarded as fibrocartilage were viewed by Schaffer as hyaline-cell chondroid tissue. He had a narrow vision of 'true' cartilage and called tissues where the cells were not shrunken in lacunae, 'chondroid'.
    [Show full text]
  • Anatomy of Major Duodenal Papilla Influences ERCP Outcomes
    Journal of Clinical Medicine Article Anatomy of Major Duodenal Papilla Influences ERCP Outcomes and Complication Rates: A Single Center Prospective Study Gheorghe G. Balan 1 , Mukul Arya 2, Adrian Catinean 3, Vasile Sandru 4,*, Mihaela Moscalu 1 , Gabriel Constantinescu 5, Anca Trifan 1 , Gabriela Stefanescu 1,* and Catalin Victor Sfarti 1 1 Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania; [email protected] (G.G.B.); [email protected] (M.M.); [email protected] (A.T.); [email protected] (C.V.S.) 2 New York Presbitarian Brooklyn Methodist Hospital, New York, NY 11215, USA; [email protected] 3 Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania; [email protected] 4 Department of Gastroenterology, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania 5 Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania; [email protected] * Correspondence: [email protected] (V.S.); [email protected] (G.S.) Received: 27 March 2020; Accepted: 25 May 2020; Published: 28 May 2020 Abstract: Background: Endoscopic retrograde cholangiopancreatography (ERCP) has been one of the most intensely studied endoscopic procedures due to its overall high complication rates when compared to other digestive endoscopy procedures. The safety and outcome of such procedures have been linked to multiple procedure- or patient-related risk factors. The aim of our study is to evaluate whether the morphology of the major duodenal papilla influences the ERCP outcomes and complication rates. Methods: A total of 322 patients with a native papilla have been included in the study over an eight month period.
    [Show full text]
  • Autologous Matrix-Induced Chondrogenesis and Generational Development of Autologous Chondrocyte Implantation
    Autologous Matrix-Induced Chondrogenesis and Generational Development of Autologous Chondrocyte Implantation Hajo Thermann, MD, PhD,* Christoph Becher, MD,† Francesca Vannini, MD, PhD,‡ and Sandro Giannini, MD‡ The treatment of osteochondral defects of the talus is still controversial. Matrix-guided treatment options for covering of the defect with a scaffold have gained increasing popularity. Cellular-based autologous chondrocyte implantation (ACI) has undergone a generational development overcoming the surgical drawbacks related to the use of the periosteal flap over time. As ACI is associated with high costs and limited in availability, autologous matrix-induced chondrogenesis, a single-step procedure combining microfracturing of the subchondral bone to release bone marrow mesenchymal stem cells in combination with the coverage of an acellular matrix, has gained increasing popularity. The purposes of this report are to present the arthroscopic approach of the matrix-guided autologous matrix-induced chondrogenesis technique and generational development of ACI in the treatment of chondral and osteochon- dral defects of the talus. Oper Tech Orthop 24:210-215 C 2014 Elsevier Inc. All rights reserved. KEYWORDS cartilage, defect, ankle, talus, AMIC, ACI Introduction Cartilage repair may be obtained by cartilage replacement: (OATS, mosaicplasty) or with techniques aimed to generate a hondral and osteochondral lesions are defects of the newly formed cartilage such as microfracture or autologous Ccartilaginous surface and underlying subchondral bone of chondrocyte implantation (ACI).9-17 the talar dome. These defects are often caused by a single or Arthroscopic debridement and bone marrow stimulation multiple traumatic events, mostly inversion or eversion ankle using the microfracture technique has proven to be an 1,2 sprains in young, active patients.
    [Show full text]
  • Vocabulario De Morfoloxía, Anatomía E Citoloxía Veterinaria
    Vocabulario de Morfoloxía, anatomía e citoloxía veterinaria (galego-español-inglés) Servizo de Normalización Lingüística Universidade de Santiago de Compostela COLECCIÓN VOCABULARIOS TEMÁTICOS N.º 4 SERVIZO DE NORMALIZACIÓN LINGÜÍSTICA Vocabulario de Morfoloxía, anatomía e citoloxía veterinaria (galego-español-inglés) 2008 UNIVERSIDADE DE SANTIAGO DE COMPOSTELA VOCABULARIO de morfoloxía, anatomía e citoloxía veterinaria : (galego-español- inglés) / coordinador Xusto A. Rodríguez Río, Servizo de Normalización Lingüística ; autores Matilde Lombardero Fernández ... [et al.]. – Santiago de Compostela : Universidade de Santiago de Compostela, Servizo de Publicacións e Intercambio Científico, 2008. – 369 p. ; 21 cm. – (Vocabularios temáticos ; 4). - D.L. C 2458-2008. – ISBN 978-84-9887-018-3 1.Medicina �������������������������������������������������������������������������veterinaria-Diccionarios�������������������������������������������������. 2.Galego (Lingua)-Glosarios, vocabularios, etc. políglotas. I.Lombardero Fernández, Matilde. II.Rodríguez Rio, Xusto A. coord. III. Universidade de Santiago de Compostela. Servizo de Normalización Lingüística, coord. IV.Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, ed. V.Serie. 591.4(038)=699=60=20 Coordinador Xusto A. Rodríguez Río (Área de Terminoloxía. Servizo de Normalización Lingüística. Universidade de Santiago de Compostela) Autoras/res Matilde Lombardero Fernández (doutora en Veterinaria e profesora do Departamento de Anatomía e Produción Animal.
    [Show full text]
  • New Insights Into the Secretory Functions of Brown Adipose Tissue
    243 2 Journal of J Villarroya et al. Secretory functions of brown 243:2 R19–R27 Endocrinology adipose tissue REVIEW New insights into the secretory functions of brown adipose tissue Joan Villarroya, Rubén Cereijo, Aleix Gavaldà-Navarro, Marion Peyrou, Marta Giralt and Francesc Villarroya Departament de Bioquímica i Biomedicina Molecular and Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Catalonia, Spain CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Catalonia, Spain Correspondence should be addressed to F Villarroya: [email protected] Abstract In recent years, an important secretory role of brown adipose tissue (BAT) has emerged, Key Words which is consistent, to some extent, with the earlier recognition of the important f brown adipose tissue secretory role of white fat. The so-called brown adipokines or ‘batokines’ may play an f brown adipokine autocrine role, which may either be positive or negative, in the thermogenic function f batokine of brown adipocytes. Additionally, there is a growing recognition of the signalling f thermogenesis molecules released by brown adipocytes that target sympathetic nerve endings (such as neuregulin-4 and S100b protein), vascular cells (e.g., bone morphogenetic protein-8b), and immune cells (e.g., C-X-C motif chemokine ligand-14) to promote the tissue remodelling associated with the adaptive BAT recruitment in response to thermogenic stimuli. Moreover, existing indications of an endocrine role of BAT are being confirmed through the release of brown adipokines acting on other distant tissues and organs; a recent example is the recognition that BAT-secreted fibroblast growth factor-21 and myostatin target the heart and skeletal muscle, respectively.
    [Show full text]
  • Female Reproductive System Chapter 28
    The Female Reproductive System Chapter 28 • Female Reproductive System Anatomy • Oogenesis and the Sexual Cycle – Ovarian Cycle – Menstrual Cycle Female Reproductive System Functions: • Produce female sex hormones and gametes • Provide nutrition for fetal development • Nourish the infant after birth The Uterus • Thick-walled, pear-shaped, muscular chamber opening into vagina. • Cervix is the rounded opening of the uterus. • Two uterine tubes (also called Fallopian tubes or oviducts) branch off the uterus and terminate near the ovaries. Uterine Tubes • Also called Fallopian Tubes or Oviducts • Open-ended, muscular tube lined with secretory cells and ciliated cells that sweep secretions and peritoneal fluid towards the uterus. • Uterine Tube Regions: – narrow isthmus near the uterus – middle portion is the ampulla – flared distally into infundibulum with fimbriae • Fertilization usually occurs in ampulla or isthmus Epithelium lining the uterine tube consists of ciliated cells, goblet cells and other secretory cells. Cilia move peritoneal fluid and uterine tube secretions towards the uterus. Cervix and Vagina normally have a stratified squamous epithelium Test developed by Dr. G.N. Papanicolaou can detect cervical cancer by identifying transformed squamous cells. normal PAP smear abnormal PAP smear Histology of the Uterus • Perimetrium is the external serosa layer • Myometrium is the middle muscular layer – 1 cm thick in nonpregnant uterus – composed of smooth muscle – produces labor contractions to expel fetus during childbirth • Endometrium – simple columnar epithelium with tubular glands – stratum functionalis is superficial layer that is shed with each menstrual cycle – stratum basalis is deeper layer that regenerates a new stratum functionalis with each menstrual cycle Ovary • Ovaries produce oocytes and female hormones.
    [Show full text]
  • Has a Role in Cardiovascular and Placental Development and Is a Binding Partner of the Α4 Integrin
    Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the α4 integrin Colleen Ringa,1, Mark H. Ginsbergb, Jacob Halingb, and Ann Marie Pendergasta,1 aDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710; and bDepartment of Medicine, University of California at San Diego, La Jolla, CA 92093 Edited* by Stephen P. Goff, Columbia University College of Physicians and Surgeons, New York, NY, and approved November 30, 2010 (received for review August 19, 2010) Dynamic signals linking the actin cytoskeleton and cell adhesion properties among integrin subunits in that α4 predominantly receptors are essential for morphogenesis during development accumulates at the leading edge of migrating cells, rather than at and normal tissue homeostasis. Abi1 is a central regulator of actin focal adhesions. Moreover, α4 expression is associated with polymerization through interactions with multiple protein com- protrusive activity and enhanced cell migration; however, the plexes. However, the in vivo role of Abi1 remains to be defined. pathways that link α4 integrin to the actin-regulatory machinery The α4 integrin adhesion receptor is associated with enhanced at the leading edge have remained elusive. Here we identify Abi1 protrusive activity and regulation of directional cell migration. as a target of α4 integrin that positively regulates membrane Among integrin subunits, α4 exhibits unique properties in that it protrusion by promoting actin polymerization at sites of integrin predominantly accumulates at the leading edge of migrating cells; engagement. however, the pathways that link the actin-regulatory machinery to The Abi family proteins, Abi1 and Abi2, were originally id- α4 at the leading edge have remained elusive.
    [Show full text]