95 Journal of Bioscience and Applied Research, Sep.2017, Vol.3, No.3, PP.95-130 pISSN: 2356-9174, eISSN: 2356-9182 JBAAR Journal of Bioscience and Applied Research WWW.JBAAR.ORG Gene-Behavior Theory: Relation between behavioral deviation and satellite DNA causing increased selective disease susceptibility within communities Seif Salah-Eldin Mohammed Department of Immunology and Allergy, Medical Research Institute, Alex, Egypt.
[email protected] +201111017413/ +201202025770 Abstract: The regional differences in the mix of cancers and diseases provoke many questions regarding the causes that control the susceptibility, in this work, it is proven that the behavioral deviance is the main cause for the increased selective disease susceptibility through cross-sectional studies. Theoretically, it is suggested that human leucocyte antigens is a marker for a deviated ancestors, and satellite DNA is an expression to the common-sense and reflects the behavior (The Gene-Behavior Theory), causing increased disease susceptibility if deviated. The conformity approach which used in the human-community theory explain many social and genetic mechanisms, especially, how human-human interactions affect the genetic damage/repair. Keywords: Disease susceptibility. Behavioral deviation. Common sense. HLA. Satellite DNA. Genetic repair. The Gene-Behavior Theory. Introduction: Cancer constitutes an enormous burden on society in more and less developed countries, and has more and less economically developed countries surpassed breast cancer as the leading cause