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VETERINARY MEDICINES A compact collection of information on Veterinary drugs/medicines in practice Prepared By : Dr. ANWAR ALAM KHAN eMail and FaceBook : [email protected] Sep-2013 CHAPTERS 1 Gastrointestinal & Hepatobiliary System 2 Infection and Infestations 3 Cardiovascular System 4 Nervous System 5 Respiratory System 6 Allergic Disorders 7 Urinary System 8 Genital System 9 Eye & Ear 10 Topical Applications 11 Nutrition and Metabolism 12 Exclusive Formulations 13 Surgical 14 Livestock Biologicals 15 Diagnostics 16 Ayurvedics Page 2 1...Gastrointestinal & Hepatobiliary System GASTROINTESTINAL & HEPATOBILIARY SYSTEM Antemetics PROMETHAZINE Phenothiazines. Anti-Histaminic, H1 receptar antagonist Phenergan NPIL Promethazine inj 2ml Dog 1-2ml--IM or Nausea, Vomition Slow-IV syp 60 ml tab 10mg Dog 25mg DOMPERIDONE Dopamine receptar Antagonist Domstal Torrent Domperidone drops 5 ml Dog Puppies, 2--3 Nausea, Vomiting. drops susp 30 ml Dog 5-10 ml orally tab 5,10,20 mg Dog 1-2 tab before meals Vomistop Cipla Domperidone drops 30ml Dog 5-10 ml tab 10mg Dog 1-2 tab METACLOPRAMIDE Perinorm IPCA Metaclopramide inj 2ml, 10ml Dog 0.05~2ml--IV Nausia, Vomition liq 30 ml Dog 5-10 ml tab 5mg, 10mg, Dog 5-10 mg DT-5mg ONDANESTRON Belongs to the class of serotonin (5HT3) antagonists Emeset Cipla Ondanestron inj 2ml, 4ml Dog 2-4 ml Nausea, Vomiting syp 30 ml Dog 5-10 ml orally tab 4mg, 8mg Dog 4mg, 8mg Ondem Alkem Ondanestron inj 2ml, 4ml Dog 1--2 ml, IM Nausea, Vomiting (2mg/ml) susp 30 ml Dog Page 3 1...Gastrointestinal & Hepatobiliary System Antacids, AntiReflux Agents & AntiUlcerants H2 Antagonist RANITIDINE Aciloc Cadila Ranitidine inj 2 ml (25mg/ml) Dog 1--2 ml, IM, IV tab 150, 300 mg Dog 150 mg Zinetac GSK Ranitidine inj 2 ml (25mg/ml) Dog 2 ml, IM,IV tab 150, 300 mg Dog 150 mg Proton pump inhibitors OMEPRAZOLE Ocid Zydus Omeprazole inj 40mg Dog AntiReflux & AntiUlcerants PANTOPRAZOLE PAN Alkem Pantoprazole inj 40 mg Dog 20--40 mg IV Gastro-oesophageal infusion reflux tab 20, 40 mg Dog Small dog 10- 20mg; Large dog 20-40mg Pantop Aristo Pantoprazole inj 40 mg Dog 20--40 mg IV Gastro-oesophageal infusion reflux tab 20, 40 mg Dog 20--40 mg Pantop-D Aristo Pantoprazole 20mg tab 20+10 mg Dog 1 OD Gastro-oesophageal + Domperidone reflux, Anti-emetic 10mg Other 7-LA FDC Al(OH), Mg(OH), susp 200 ml Dog 5 ml, BD Antacid Simethicone, Oxetacaine Gelusil-MPS Pfizer Dimethicone, liq 170ml Antacid Mg(OH), Al(OH) tab 10's Page 4 1...Gastrointestinal & Hepatobiliary System GI sedatives, Antispasmodic, Prokinetics DICYCLOMINE HCL Cyclopam Indoco Rem Dicyclomine drops 10 ml GIT Spasm susp 30 ml tab 20mg (Dicyclo. Dog 10mg, TID 20mg + Paracetamol 500mg) Marcogesic Marc Fenpiverinium inj 30 ml GIT Spasm Spas Bromide, Piroxicam, Pitofenone Meftal-Spas Blue Cross Dicyclomine drops 10 ml Dog Pups - 5--10 GIT Spasm (Dicyclomine + drops Simethicone) susp 30 ml Dog (Dicyclomine + Simethicone) tab (Dicyclomine- Dog 10mg + MefenamicAcid 250mg) Nobigan Novitech Dicyclomine, bolus 2's GIT Spasm Paracetamol inj 30 ml Large Animals 15--30 ml Spasmo- Wockhardt Dicyclomine inj 2, 30 ml GIT Spasm proxyvon Spasmo- Wockhardt Diclofenac + inj 2 ml Dog 2 ml GIT Spasm proxyvon Dicyclomine Forte Page 5 1...Gastrointestinal & Hepatobiliary System Antidiarrhoeals/ GI anti-infectives Antibiotic+Antiprotozoals CIPROFLOXACIN, TINIDAZOLE, ... Cflox-Tz Intas Ciprofloxacin + bolus 2 boli Large Animals 1--2 bol. BD Tinidazole tab 10 tabs Small Animals 1 BD Cifomed-TZ Aglowmed Ciprofloxacin + tab (Cip.500mg + Tinidazole Tin.600mg) METRONIDAZOLE, FURAZOLIDONE, ... Flagyl-F Piramal HC Metronidazole + susp 60 ml Furazolidone tab (400+100) Marcogyl-LM Marc Metronidazole, bolus 2's Large Animals 1--2 bol, BD Furazolidone, Loperamide Small Animals 1/2--1 bol, BD Metrofural Alembic Metronidazole + bolus 4's Small Animals 1--2 boli/day Furazolidone Large Animals 4--6 boli/day Vetfur-TL Dosch Metronidazole + bolus Metro.1000mg All Animals 1 bol / 50Kg Furazolidone + + Furaz.200 + Loperamide + Lope. + Tinidazole Tinida.1500mg OFLOXACIN, TINIDAZOLE, ORNIDAZOLE, ... DOT Pail Ofloxacin + bolus 2's Small Animals 1/2-BD Infectious Diarrhoea Tinidazole + Dicyclomine + Dimethicone Large Animals 1-BD Marcogyl-OZ Marc Ofoxacin 1000mg + bolus 4's Large Animals 2 BD Infectious Diarrhoea Ornidazole 2500mg Small Animals 1 BD Oflokind-OZ Mankind Ofoxacin.1000 + bolus 2 bol Small Animals 1/2 BD x 5 days Infectious Diarrhoea Ornidazole.2500 mg Large Animals 1 BD x 5 days Oflox-TZ Cipla Ofoxacin + Tinidazole susp 30ml, 60ml Infectious Diarrhoea Zenflox-OZ Mankind Ofoxacin.200 + susp 30 ml Infectious Diarrhoea Ornidazole.500 mg NORFLOX, TINIDAZOLE, METRONIDAZOLE, .. Marcogyl-TZ Marc Norflox 1.2g + bolus 4's Diarrhoea Tinidazole 1.8g Powergyl Cipla Norflox + susp 30ml, 60ml Small Animals 5-10 ml, BD Metronidazole tab 400mg+500mg Small Animals 1 BD tab HALQUINOL 3 Care Vetcare Halquinol bolus 6's Large Animals 1--2 x BD Small Animals 1/3 -- 1/2 x BD Page 6 1...Gastrointestinal & Hepatobiliary System FURAZOLIDONE, KAOLIN Marcogyl Marc Furazolidone, bolus 4's Small Animals 0.5--1 bol, BD Diarrhoea Hydroxyquinolone, Kaolin Large Animals 2--4 bol, BD Page 7 1...Gastrointestinal & Hepatobiliary System Carminatives, Enzymes, Digestives, Rumen tonics, Antizymotics, Antiflatulants Carminatives, Enzymes, Digestives, Rumentonics CARMINATIVES, ENZYMES, DIGESTIVES, RUMENTONICS Digyton Himalaya Herbal drops 30 ml Dog Pups - 5 drops Indigestion, BD ; Dogs-1-2ml dyspepsia, colic, BD flatulence and gastrointestinal upsets in weaned puppies HB Strong Himalaya pow 10gm sachet All Animals 1/2 -- 1 sachet daily Ketonex Pfizer Sod. dihydrogen bolus 4's Sheep/Goat 1/2 daily Anorexia, Ketosis phos., Nicotinic acid, Yeast Cattle/Buffalo 2 BD Provisac Plus Vetcare Probiotics, Vits, AA, bolus 2's Large Animals 1--2 bol x BD Anorexia, Indigestion Enzymes Rumbion Himalaya Herbal bolus 4's Cattle/Buffalo 2 boli Sheep/Goat 1 boli Rumen-FS Alembic Co,Fe,Cu, B1,B12, bolus 4 boli Sheep/Goat 1/2 bolu, BD, Anorexia, Indigestion Yeast, Enzymes, daily Probiotic Cattle/Buffalo 2 boli, BD, daily Rumentas Intas Co,Fe,Cu, bolus 4 boli Cattle/Buffalo 2 BD Anorexia, Indigestion AntimonyPot.Tart Rumenton Pfizer AntimonyPot.Tart, tab Tin of 50 tabs Cattle/Buffalo 1--2 tab/day x 2-- Anorexia, Indigestion Fe 3 days Rumicare Vet Intervet Ca, Methionine, pow Sachet (32g, Sheep/Goat 32g.BD Anorexia, Indigestion Picorhiza,Co, B6, 65g, 125g, Dextrose 500g) Cattle/Buffalo Adult-125g.BD Rumipro Natural Herbal bolus 6's Large Animals 2.BD x 3days Anorexia, Indigestion Remedies Small Animals 1.BD x 3days RumisacC Pfizer Probiotics, Enzymes, bolus 4's Cattle/Buffalo 2--4 bol x 5 days Anorexia, Indigestion AA, LivExt, .... Start Pail Yeast, LA.Bacillus, bolus 4's Large Animals 2 bol x BD Indigestion AA, Ginger, Cu, Co, LivExt, B12, B1, Mag.Tri.Silicate, Ca.PO4 Small Animals 1/2--1 bol x BD Tonakind Mankind Probiotics, Vits, bolus 2's Large Animals 1--2 boli Anorexia, Indigestion Mins, Enzymes, Ca, LivExt Page 8 1...Gastrointestinal & Hepatobiliary System Antizymotics, Antiflatulants Deblota Mankind AlOH, MgOH, susp 100 ml Small Animals 20 ml Bloat Simethicone, Dill Oil Large Animals 100 ml Tyrel Natural Herbal susp 100 ml Cattle/Buffalo 100 ml Bloat Remedies Sheep/Goat 50 ml Hepato-Biliary drugs Herbal Liv-52 Vet Himalaya Herbal drops 30 ml Dog Pups- 5-8 drops Liver Tonic BD liq 110 ml, 1-Ltr Dog 5ml BD pow 100 gm All Animals 5-10 gm daily tab 60's All Animals 1-2 tabs daily Vetoliv Dosch susp 200 ml Cattle/Buffalo 40 ml/day Liver Tonic Small Animals 5--10 ml/day Zigbo Natural Herbal bolus 10's Large Animals 2 daily Liver Tonic Remedies Small Animals 1 daily liq 300ml, 1.ltr, Small Animals 10ml daily 5.ltr Large Animals 30ml daily Page 9 2...Infection and Infestations INFECTION AND INFESTATIONS Antibiotics / Antibacterials Penicillins PROCAINE PENICILLIN Bistrepen Alembic Procaine Penicillin + inj 4 Lacs IU; 10 Penicillin_G Lacs IU; 40 Lacs IU Bistrepen-V Alembic Procaine Penicillin + inj (20Lacs+2.5g) Large Animals 2.5 gm Gm +ve & -ve Bact. LD Penicillin_G + Vial Streptomycin Small Animals 0.5--1 gm Dicrysticin-DS Zydus Procaine Penicillin G inj 5 gm Large Animals 30 Lakh iu Penicillin G 10 Lakh iu Streptomycin 5g Dicrysticin-S Zydus Procaine Penicillin G inj 2.5gm 15 Lakh iu Penicillin G 5 Lakh iu Streptomycin 2.5g Dicrysticin-S Zydus Procaine Penicillin G inj 2.5 gm Large Animals . LD 15 Lakh iu Penicillin G 5 Lakh iu Streptomycin 2.5g FPP Alembic Procaine Penicillin, inj 04, 20, 40 Lacs Large Animals 20--40 Lacs or 10- PenicillinG IU 20 ml Small Animals 2--5 Lacs or 1-2 ml FPP-20, FPP- Zydus Procaine Penicillin, inj 20 Lakh, 40 40 PenicillinG Lakh PAM Zydus Procaine PenicillinG inj 10 ml (30 Lakh Dog & Cat 1--2 ml; deep IM Long acting; (3 Lakh IU/ml) IU) Mastitis; Metritis; Wounds; Anthrax; HS; BQ; Strangles; UTI; Navell ill Large Animals 30 Lakh IU / 300Kg (10 ml); deep IM AMPICILLIN AC-Vet Intas Ampicillin + inj 2gm, Large Animals 2--3 gm, IM,IV Cloxacillin 3gm(Forte) Betalactin Unichem Ampicillin + inj 500mg, 2g Small Animals 500 mg Cloxacillin Large Animals 2 gm Clampivet-S Dosch Ampicillin + inj 3 gm Large Animals 3 gm, IM, BD Sulbactam Cloxam Marc Ampicillin + inj 2, 3, 4 gm Cloxacillin RC-Forte-D Pfizer Ampicillin + inj 4 g Large Animals 4 gm, IM, IV Dicloxacillin Roscillin Pfizer Ampicillin inj 2.5g Large Animals 2.5g, IM, IV, SC Page 10 2...Infection and Infestations AMOXICILLIN Acromin Novitech Amoxicillin, bolus 2gm (Amox + Large Animals 1 bol x BD RTI, GIT, UTI Cloxacillin Diclox) inj 3.5gm Large Animals 3.5gm (follow with Acromin bolus in Evening)
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    ii Antibiotic Use Guidelines for Companion Animal Practice (2nd edition) iii Antibiotic Use Guidelines for Companion Animal Practice, 2nd edition Publisher: Companion Animal Group, Danish Veterinary Association, Peter Bangs Vej 30, 2000 Frederiksberg Authors of the guidelines: Lisbeth Rem Jessen (University of Copenhagen) Peter Damborg (University of Copenhagen) Anette Spohr (Evidensia Faxe Animal Hospital) Sandra Goericke-Pesch (University of Veterinary Medicine, Hannover) Rebecca Langhorn (University of Copenhagen) Geoffrey Houser (University of Copenhagen) Jakob Willesen (University of Copenhagen) Mette Schjærff (University of Copenhagen) Thomas Eriksen (University of Copenhagen) Tina Møller Sørensen (University of Copenhagen) Vibeke Frøkjær Jensen (DTU-VET) Flemming Obling (Greve) Luca Guardabassi (University of Copenhagen) Reproduction of extracts from these guidelines is only permitted in accordance with the agreement between the Ministry of Education and Copy-Dan. Danish copyright law restricts all other use without written permission of the publisher. Exception is granted for short excerpts for review purposes. iv Foreword The first edition of the Antibiotic Use Guidelines for Companion Animal Practice was published in autumn of 2012. The aim of the guidelines was to prevent increased antibiotic resistance. A questionnaire circulated to Danish veterinarians in 2015 (Jessen et al., DVT 10, 2016) indicated that the guidelines were well received, and particularly that active users had followed the recommendations. Despite a positive reception and the results of this survey, the actual quantity of antibiotics used is probably a better indicator of the effect of the first guidelines. Chapter two of these updated guidelines therefore details the pattern of developments in antibiotic use, as reported in DANMAP 2016 (www.danmap.org).
  • Committee for Veterinary Medicinal Products

    Committee for Veterinary Medicinal Products

    The European Agency for the Evaluation of Medicinal Products Veterinary Medicines Evaluation Unit EMEA/MRL/217/97-FINAL January 1998 COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS PROCAINE SUMMARY REPORT 1. Procaine (p-aminobenzoyl-diethylaminoethanol; synonym: novocaine), is a water-soluble local anaesthetic. Procaine is an amino ester. It is used in cattle, sheep, goats and horses for minor surgical procedures particularly dehorning by subcutaneous injection, and for local and regional anaesthesia by infiltration or nerve block. The common therapeutic doses ranged from 25 to 250 mg per animal. In humans, though procaine formerly was used widely, its use is now confined to infiltration anaesthesia and occasionally for diagnostic nerve block. When it is used as a local anaesthetic, dosages of up to 1000 mg procaine hydrochloride have been used, although doses of 600 mg are more common. In humans, the systemic analgesia can be observed after subcutaneous injection of 100 to 800 mg of procaine. Procaine is also used as a part of the complex procaine benzylpenicillin, which is an active constituent of various intramammary and parenteral products in veterinary as well as in human medicine. Procaine when combined with benzylpenicillin can prolong the pharmacological effects of benzylpenicillin, reducing the solubility of the latter. This form is an equimolecular mixture of procaine and benzylpenicillin. Procaine benzylpenicillin has the same antimicrobial action as benzylpenicillin, but because of the relatively low blood concentration produced, its use should be restricted to infections caused by micro-organisms that are highly sensitive to penicillin. 2. Procaine acts on the central nervous system, cardiovascular system, neuromuscular junctions and ganglion synapse.
  • 1: Gastro-Intestinal System

    1: Gastro-Intestinal System

    1 1: GASTRO-INTESTINAL SYSTEM Antacids .......................................................... 1 Stimulant laxatives ...................................46 Compound alginate products .................. 3 Docuate sodium .......................................49 Simeticone ................................................... 4 Lactulose ....................................................50 Antimuscarinics .......................................... 5 Macrogols (polyethylene glycols) ..........51 Glycopyrronium .......................................13 Magnesium salts ........................................53 Hyoscine butylbromide ...........................16 Rectal products for constipation ..........55 Hyoscine hydrobromide .........................19 Products for haemorrhoids .................56 Propantheline ............................................21 Pancreatin ...................................................58 Orphenadrine ...........................................23 Prokinetics ..................................................24 Quick Clinical Guides: H2-receptor antagonists .......................27 Death rattle (noisy rattling breathing) 12 Proton pump inhibitors ........................30 Opioid-induced constipation .................42 Loperamide ................................................35 Bowel management in paraplegia Laxatives ......................................................38 and tetraplegia .....................................44 Ispaghula (Psyllium husk) ........................45 ANTACIDS Indications: