Safety Assessment of Fluoropolymers as Used in Cosmetics Status: Draft Report for Panel Review Release Date: February 9, 2018 Panel Date: March 5-6, 2018 The 2018 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Ronald A. Hill, Ph.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Executive Director is Bart Heldreth, Ph.D. This report was prepared by Wilbur Johnson, Jr., M.S., Senior Scientific Analyst © Cosmetic Ingredient Review 1620 L STREET, NW, SUITE 1200 ◊ WASHINGTON, DC 20036-4702 ◊ PH 202.331.0651 ◊ FAX 202.331.0088 ◊
[email protected] Commitment & Credibility since 1976 Memorandum To: CIR Expert Panel Members and Liaisons From: Wilbur Johnson, Jr. Senior Scientific Analyst Date: February 9, 2018 Subject: Draft Report on Fluoropolymers A Scientific Literature Review (SLR) on Fluoropolymers was issued on January 8, 2018. The attached use concentration data (fluoro032018data1 and fluoro032018data2) that are included in this draft report were received from the Personal Care Products Council (Council) prior to issuance of the SLR. Data relating to the skin irritation and sensitization potential and ocular irritation potential of formulas containing PTFE (fluoro032018data3) and report comments (fluoro032018pcpc1) were received from the Council after the SLR was issued. These data are included in the draft report, and the Council’s comments have been addressed. Additionally, a memorandum with report comments (fluoro032018pcpc2) was received from the Cosmetic Ingredient Review (CIR) Science and Support Committee of the Council.