bioRxiv preprint doi: https://doi.org/10.1101/715870; this version posted July 26, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 2 Mitochondria branch within Alphaproteobacteria 3 4 Lu Fan1,2¶, Dingfeng Wu3¶, Vadim Goremykin4¶, Jing Xiao3, Yanbing Xu3, Sriram Garg6, Chuanlun 5 Zhang2,5, William F. Martin6*, Ruixin Zhu3,2* 6 1 Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology 7 (SUSTech), Shenzhen 518055, China 8 2 Shenzhen Key Laboratory of Marine Archaea Geo-Omics, Department of Ocean Science and Engineering, 9 Southern University of Science and Technology (SUSTech), Shenzhen 518055, China 10 3 Putuo people's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, 11 P.R.China. 12 4 Research and Innovation Centre, Fondazione E. Mach, 38010 San Michele all’Adige (TN), Italy 13 5 Laboratory for Marine Geology, Qingdao Pilot National Laboratory for Marine Science and Technology, 14 Qingdao, 266061, China 15 6 Institute of Molecular Evolution, Heinrich-Heine-University, Universitätsstr. 1, 40225 Düsseldorf, 16 Germany 17 18 ¶ These authors contribute equally to this work. 19 * Corresponding authors: 20 William F. Martin (
[email protected]) 21 Ruixin Zhu (
[email protected]) 22 23 It is well accepted that mitochondria originated from an alphaproteobacterial-like ancestor. However, 24 the phylogenetic relationship of the mitochondrial endosymbiont to extant alphaproteobacteria 25 remains a subject of discussion.