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Danzhou Yang 2010 CURRICULUM VITAE NAME: Danzhou Yang TITLE: Associate Professor ADDRESS: Division of Medicinal Chemistry Department of Pharmacology & Toxicology College of Pharmacy University of Arizona Tucson, AZ 85721-0207 PHONE: (520) 626-5969 FAX: (520) 626-6988 E-mail: [email protected] WEB SITE: http://www.pharmacy.arizona.edu/copdirectory/dispperson.pl?person=yangd GENDER Female DATE OF BIRTH March 5, 1969 Education Date Institution Degree (field, advisor) 1998 University of Kentucky Postdoctoral Fellow. (Pharmaceutical Sciences, T. G. Burke) 1996 University of Illinois Ph.D. (Biophysics, A. H.-J. Wang) at Urbana-Champaign 1989 University of Science and B.S. (Molecular & Cell Biology, W. Huang) Technology of China (Special Class for Gifted Young) Professional Experience Dates Institution Position 2009-2011 American Association Co-Chair, Young Chemists Committee, Chemistry for Cancer Research in Cancer Research 2008 - present University of Arizona Associate Professor of Chemistry 2008 - present University of Arizona Associate Professor of Medicinal Chemistry 2008 - present University of Arizona Director, Drug Discovery and Development Graduate Program 2005 - present University of Arizona Faculty Member, BIO5 Institute 2002 - present University of Arizona Comprehensive Member, Arizona Cancer Center, Therapeutic Development Program 2001 - present University of Arizona Faculty Member, Biological Chemistry Program 2001 - present University of Arizona Faculty Member, Undergraduate Biology Research Program 2001 - Present University of Arizona Director, College of Pharmacy NMR facility 1 Danzhou Yang 2010 2001 - 2007 University of Arizona Assistant Professor of Medicinal Chemistry 1999 - 2000 University of Kentucky Research Assistant Professor of Chemistry 1996 - 1998 University of Kentucky Postdoctoral Fellow in Pharmaceutical Sciences 1991 - 1996 University of Illinois Graduate Research/Teaching Assistant at Urbana-Champaign 1990 - 1991 University of Illinois Graduate Research Assistant at Urbana-Champaign Honors and Recognitions 1984-89 The Exclusive Special Class for Gifted Young in China Honor Graduate, University of Science & Technology of China 1996 Francis M. and Harlie M. Clark Research Support Grant, University of Illinois 1996 Student Paper Competition Award by Sigma Xi Scientific Research Society, University of Illinois 1996 Graduate College Thesis Project Award, University of Illinois 2000 Howard-Temin Career Development Award, National Cancer Institute, National Institutes of Health 2004 NIH Special Emphasis Panel member 2009-11 Co-Chair, Young Chemist Committee, Chemistry in Cancer Research, AACR 2009 NIH MSFB study section ad hoc member 2009 Session Chair, “Chemistry in Support of Cancer Drug Discovery I”, Chemistry in Cancer Research/AACR-American Chemical Society joint conference, New Orleans. 2009 Organizing Committee, International Symposium of NMR for Biological Macromolecules, China 2009 Advisory Board, 5th Modern Drug Discovery and Development Conference, San Diego. 2010 Session Co-Chair, “Career Paths in Cancer Drug Development” 2010 Symposium Chair, “G-Quadruplexes as Targets for Drug Discovery and Development”, ACS National meeting, Boston. 2010-16 NIH MSFB study section member Professional Societies 1996 - present American Association for Cancer Research 1996 - 2001 American Association of Pharmaceutical Scientists 1997 - present American Chemical Society 1997 - 2008 American Association for the Advancement of Science 2004-2005 American Society for Biochemistry and Molecular Biology (ASBMB) 2009-2010 The Protein Society Research Interests High-field NMR macromolecule structure determination and structure-based rational drug design, G- quadruplex DNA secondary structures and their interactions with small molecule drugs, anticancer drugs that inhibit transcription factors, topoisomerase I inhibitors. PROFESSIONAL ACTIVITIES 2 Danzhou Yang 2010 Teaching Experience *University of Arizona, College of Pharmacy 2001-present PCOL 420 (Case Studies in Pharmacology, 1 unit) – facilitator of 2-3 cases/semester 2001-present PCOL 421 (Case Studies in Pharmacology, 1 unit) – facilitator of 2-3 cases/semester 2001-present PCOL 837(437)/537A (Medicinal Chemistry, 3 units) – course lecturer 2007 PCOL 837/537A (Medicinal Chemistry, 3 units) – course coordinator and lecturer 2001-present PHSC 596A (Medicinal Chemistry and Developmental Therapeutics Seminar Series, 1 unit) – course coordinator 2001-present BIOC 595B (Biological Chemistry Journal Club, 1 unit) – course co-coordinator 2001-present PCOL 695A (Research Conference, 1 unit). 2001 GENE 670 (Recent Topics in Genetics, 2 units) – guest lecturer 2001 CBIO 596H (Cancer Biology Series, 1 unit) – guest lecturer 2003-present PCOL 530 (Proteins and Nucleic Acids as Drug Targets, 3 units) course lecturer 2003-present PHSC 670 (Drug Design, Development and Discovery, 3 units) course lecturer 2004 CHEM/PHSC 549 (Chemistry of Natural Products, 3 units) course lecturer Students Supervised University of Kentucky, Department of Chemistry Graduate Student Research Advisor to: Li Jie (2000) Liu Xinli (2000) Undergraduate Research Advisor to: Alex Bingcang (1999-2000) *University of Arizona, College of Pharmacy Postdoctoral Advisor to Jixun Dai (2001-present) Zhizhong Meng (2002-2004) Attila Ambrus (2003-2006) Emmanouil Chatzakis (2008-2010) Ravi Mathad (2008-present) Graduate Student Thesis Advisor to Chanda Adikaram, BCP/Medicinal Chemistry, 2001-2006, Ph.D. (2002 and 2003 BCP fellowship recipient) Dissertation: DNA and DNA-interacting proteins as anticancer drug targets. Ding Chen, BCP/Medicinal Chemistry, 2003-2007, Master of Science. Dissertation: Structure and drug-binding study of G-quadruplexes. Kaika Okamoto, Pharmacology and Toxicology, 2008-2009. Jessica Foritn, Medicinal Chemistry, 2008-present, Ph.D. Co-advisor Yuwei Chen, Chemistry, 2010-present, Ph.D. 3 Danzhou Yang 2010 Ph.D. Dissertation Committee of Tom Dexheimer (2001-2006, Medicinal Chemistry/BCP) Fei Hong (2001-2005, Medicinal Chemistry) Hongliang Jiang (2001-2005, Medicinal Chemistry) Zhengzhi Xie (2001-2007, Medicinal Chemistry) Aik Teong Ooi (2002-2008, Medicinal Chemistry/BCP) Qian Cheng (2002-2007, Medicinal Chemistry/BCP) Yong Qin (2003-2008, Medicinal Chemistry/BCP) Tiffanie Bialis (2003-2006, Medicinal Chemistry/BCP) Ashley Fisher (2003-2009, Medicinal Chemistry/BCP) Wendy Hartsock (2004-2006, Medicinal Chemistry/BCP) Kexiao Guo (2004-2008, Medicinal Chemistry/BCP) Hong Gao (2004-2007, Pharmacology and Toxicology) Mital Bhakta (2005-present, Medicinal Chemistry/BCP) Diana J. Uribe (2007-, Cancer Biology) SunMi Lee (2008-2009, Cancer Biology) Visiting Ph.D. Student Advisor to Daniel (Zhenjiang) Zhang Undergraduate Research Advisor to Beth Rosenberger (2001-2002, Pharmacy student) Alicia Newkirk (2001, Pharmacy student) Adrienne Kiehle (2003-2006, UBRP student, Physiological Sciences) Ly Ho (2003-2004, senior thesis, Biochemistry and Molecular Biophysics) Adrian De Alba (2004-2006, Minority Health Disparities Program) Lucy Sanchez Covarrubias (2006, Minority Health Disparities Summer Program) Mimi Tat (2006-2007, Senior Honors Thesis, Molecular and Cellular Biology) Irene Alderete (2007 Summer, Arizona Biology Network Summer Program) Matthew R. Karolak (2007-2008, Biochemistry) Marti Larriva (2007-present , Chemistry) Newsha Sarmadnia (2007-2009, Biochemistry) Bobby Abdallah (2009- present, Chemistry and Biochemistry) Frank W. Li (2010-present, Physiology) UA Graduate College Summer Research Opportunities Program Monica Alvarez Malvido, La Salle University, Mexico D.F (2008, Mexico-UA Summer Research Program) Host of Visiting Scientist Jincheng Hu (2002-2003, visiting scientist) Host for Local High School Student Intern Jessica Wang (2001). Graduate Student Rotation Advisor to 4 Danzhou Yang 2010 Chanda Adikaram (Fall 2001, BCP/Biochemistry) Hongliang Jiang (Fall 2001, Medicinal Chemistry) Fei Hong (Spring 2002, Medicinal Chemistry) William Taylor (Fall 2002, BCP/Biochemistry) Josh Black (Fall 2002, Medicinal Chemistry) Qian Cheng (Fall 2002, Medicinal Chemistry) Aik-teong Ooi (Spring 2003, BCP/Medicinal Chemistry) Ding Chen (Spring 2003, BCP/Biochemistry) Sonia Ahuja (Fall, 2003, Medicinal Chemistry) Justin Dietrich (Fall, 2004, Medicinal Chemistry/BCP) Davide Botta (Fall, 2004, Medicinal Chemistry/BCP) Katherine Block (Fall, 2004, Medicinal Chemistry/BCP) Samuel Jayankathan (Spring, 2005, BCP/Biochemistry) Vineela Kadiyala (Summer, 2007, BCP/Chemistry) Xi Chen (Fall, 2009, Medicinal Chemistry) Liu Qi Chen (Fall, 2009, BCP) Frank Tedeschi (Spring, 2010, BCP) Cory Burgess (Summer, 2010, DDD) Pharmacy Student Advisor to Kathryn Matthias (2001-2005) Robert Montierth (2001-2005) Robert Moore (2001-2005) Alicia Newkirk (2001-2005) Yen Nguyen (2001-2005) Sarah Nii (2001-2005) Brian Moran (2002-2006) Zhinus Bahraini (2003-2007) Katherine Tauson (2003-2007) Nisha Donda (2004-2008) Caroline Sepp (2004-2008) Courtney Weiser (2005-2009) Matthew Potter (2006-2010) Guadalupe Sandoval (2006-2010) Jesus Solis (2006-2010) Kateryna Yenina (2006-2010) Amy Gowler (2007-2011) Jennifer Schiefer (2007-2011) Katherine Schiraldi (2007-2011) Tracy Post (2008-2012) May Li (2009-2013) 5 Danzhou Yang 2010 Interdisciplinary Program and Training Grant Participation Pharmaceutical Sciences - Medicinal Chemistry Graduate Program Biological Chemistry Interdisciplinary Graduate Program (BCP) Cancer Biology Interdisciplinary Graduate Program (CBIG) Undergraduate Biology Research Program (UBRP) UA Minority Access to Research