Ion Channels in Health and Disease: A Symposium to Celebrate the 50th Anniversary of the Award of the Nobel Prize to Alan Hodgkin and Andrew Huxley
Preliminary Symposium Programme
Symposium Day One: Monday 16th September, 2013
Registration from 08.00 Opening of the Symposium Chair: Professor Ole Paulsen / Dr Hugh Robinson, Dept of Physiology, Development and Neuroscience 08.45-09.00 Welcome by The Master of Trinity College, Sir Gregory Winter 09.00-09.40 Professor King-Wai Yau, John Hopkins University, USA
Session One: Sodium channels and neuronal excitability Chair: Professor Alastair Compston, Department of Clinical Neurosciences 10.10-10.50 Professor Bill Catterall, University of Washington, USA “Structure and function of voltage-gated sodium channels at atomic resolution” 10.50-11.20 Professor Simon Laughlin, Department of Zoology, University of Cambridge ”Why does a low power brain use high power action potentials?” 11.20-12.00 Professor Stephen Waxman, Yale School of Medicine, USA “Fire, Fantoms and Fugu: Sodium Channels from Squid to Clinic” 12.00-13.15 Lunch and Poster Session / Hodgkin-Huxley exhibition
Session Two: Potassium channels and neuronal function Chair: Professor Bill Harris, Department of Physiology, Development and Neuroscience 13.15-13.55 Professor Lily Jan, Howard Hughes Medical Centre, USA ”Voltage-gated potassium channels in health and disease” 13.55-14.25 Dr Hugh Robinson, Department of PDN, University of Cambridge “Potassium channels and spike patterns in cortical interneurons” 14.25-15.05 Professor Dimitri Kullmann, University College London, UK ”Shaker potassium channels: from genetic disease to gene therapy” 15.05-15.35 Refreshments
Session Three: Light-activated channels and cortical circuits Chair: Professor Wolfram Schultz, Department of Physiology, Development and Neuroscience 15.35-16.15 Professor Peter Hegemann, Humboldt-Universitat zu Berlin, Germany “Light-gated ion transport: speed, direction, selectivity and limitations” 16.15-16.45 Professor Ole Paulsen, Department of PDN, University of Cambridge “The use of optogenetics to study neural plasticity”
16.45-17.30 The Alan Hodgkin Lecture Professor Karl Deisseroth, Stanford University, USA “Optical deconstruction of fully-assembled biological systems”
18.30 Reception at Trinity College hosted by the Master, Sir Gregory Winter. 19.30 Conference Dinner at Trinity College Pre dinner speech by Professor Denis Baylor, Stanford University
Symposium Day Two: Tuesday 17th September, 2013
Session Four: Ligand-gated channels and synaptic transmission (1) Chair: Professor Eric Barnard, Department of Pharmacology 09.00-09.30 Dr Nigel Unwin, MRC Laboratory for Molecular Biology, Cambridge “Gating movement of the acetylcholine receptor caught by plunge-freezing” 09.30-10.00 Dr Sarah Lummis, Department of Biochemistry, University of Cambridge “The ABC of 5-HT3 receptors” 10.00-10.40 Professor Angela Vincent, University of Oxford, UK “Antibodies and ion channels” 10.40-11.05 Refreshments
Session Five: Ligand-gated channels and synaptic transmission (2) Chair: Professor Sir Michael Berridge, Babraham Institute 11.05-11.45 Professor Shigetada Nakanishi, Osaka Bioscience Institute, Japan “Molecular diversity and synaptic mechanisms of glutamate receptors” 11.45-12.15 Dr Ingo Greger, MRC Laboratory for Molecular Biology, Cambridge “AMPA receptors - from assembly in the ER to function at synapses” 12.15-12.55 Professor Dennis Selkoe, Harvard Medical School, USA “Perturbations of neuronal receptor and channel functions in Alzheimer's Disease suggest therapeutic targets” 12.55-14.00 Lunch and Poster Session / Hodgkin-Huxley exhibition
Session Six: Cortical circuits Chair: Professor Trevor Robbins, Department of Psychology 14.00-14.45 The Andrew Huxley Lecture Professor Bert Sakmann, Max Planck Institute of Neurobiology, Germany “Cortical circuits” 14.45-15.25 Professor Troy Margrie, MRC National Institute for Medical Research, London, UK “Biophysical diversity and connectivity of neuronal networks” 15.25-15.55 Professor Ed Bullmore, Department of Psychiatry, University of Cambridge “Brain connectomics from macro to micro 15.55-16.20 Refreshments
Session Seven: TRP channels and sensation Chair: TBC 16.20-16.50 Professor David Julius, University of California, USA "From Peppers to Pit Vipers: Molecular mechanisms of thermosensation and pain” 16.50-17.20 Professor Roger Hardie, Department of PDN, University of Cambridge ”TRP channels and phototransduction in Drosophila” 17.20-17.50 Professor Peter McNaughton, Department of Pharmacology, University of Cambridge ”Modulation of TRP channels - fundamental mechanisms and in vivo significance" 17.50-18.20 Professor Michael Tymianski, University of Toronto, Canada “Role of TRPM7 channels in ischemic cell death”
Public Programme and Outreach Lecture: Chair: Professor Barbara Sahakian, Department of Psychiatry 18.20-18.30 Public arrive 18.30-18.45 Dance performance, Professor Nicola Clayton, Department of Psychology 18.45-19.30 Professor Fran Ashcroft, University of Oxford, UK