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Short Parietal Lobe Connections of the Human and Monkey Brain

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Short Parietal Lobe Connections of the Human and Monkey Brain King’s Research Portal DOI: 10.1016/j.cortex.2017.10.022 Document Version Peer reviewed version Link to publication record in King's Research Portal Citation for published version (APA): Catani, M., Robertsson, N., Beyh, A., Huynh, V., de Santiago Requejo, F., Howells, H., Barrett, R. L. C., Aiello, M., Cavaliere, C., Dyrby, T. B., Krug, K., Ptito, M., D’Arceuil, H., Forkel, S. J., & Dell' Acqua, F. (2017). Short parietal lobe connections of the human and monkey brain. Cortex, 97(0), 339-357. https://doi.org/10.1016/j.cortex.2017.10.022 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. 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Download date: 30. Sep. 2021 Accepted Manuscript Short Parietal Lobe Connections of The Human and Monkey Brain Marco Catani, Naianna Robertsson, Ahmad Beyh, Vincent Huynh, Francisco de Santiago Requejo, Etta Howells, Rachel L.C. Barrett, Marco Aiello, Carlo Cavaliere, Tim B. Dyrby, Kristine Krug, Maurice Ptito, Helen D’Arceuil, Stephanie J. Forkel, Flavio Dell’Acqua PII: S0010-9452(17)30370-2 DOI: 10.1016/j.cortex.2017.10.022 Reference: CORTEX 2171 To appear in: Cortex Please cite this article as: Catani M, Robertsson N, Beyh A, Huynh V, de Santiago Requejo F, Howells E, Barrett RLC, Aiello M, Cavaliere C, Dyrby TB, Krug K, Ptito M, D’Arceuil H, Forkel SJ, Dell’Acqua F, Short Parietal Lobe Connections of The Human and Monkey Brain, CORTEX (2017), doi: 10.1016/ j.cortex.2017.10.022. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. ACCEPTED MANUSCRIPT SHORT PARIETAL LOBE CONNECTIONS OF THE HUMAN AND MONKEY BRAIN Marco Catani 1,2 , Naianna Robertsson 1,2 , Ahmad Beyh 1,2 , Vincent Huynh 1,2 , Francisco de Santiago Requejo 1,2 , Etta Howells 1,2 , Rachel L. C. Barrett 1,2 , Marco Aiello 4, Carlo Cavaliere 4, Tim B. Dyrby 5,6 , Kristine Krug 7, Maurice Ptito 7,8 , Helen D’Arceuil 9, 10 , Stephanie J. Forkel 1,2* , Flavio Dell’Acqua 1,2* . 1NatBrainLab, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. 2NatBrainLab, Sackler Institute for Translational Neurodevelopment, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. 3Spinal Cord Injury Center, Research, University of Zurich, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich. 4NAPLab, IRCCS SDN Istituto di Ricerca Diagnostica e Nucleare, Via E. Gianturco 113, Naples, Italy, 5 Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. 6 Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kongens Lyngby, Denmark. 7 Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. 8 Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, Copenhagen. 9 Ecole d’Optométrie, Université de Montréal, Montréal, Québec. 10 Athinoula A. Martinos Center, MassachusettsMANUSCRIPT General Hospital, Charlestown. * These authors have contributed equally to the study. Corresponding author: Marco Catani, NatBrainLab, PO50 Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. Email: [email protected] ACCEPTED ACCEPTED MANUSCRIPT SHORT PARIETAL LOBE CONNECTIONS OF THE HUMAN AND MONKEY BRAIN Marco Catani 1,2 , Naianna Robertsson 1,2 , Ahmad Beyh 1,2 , Vincent Huynh 1,2 , Francisco de Santiago Requejo 1,2 , Etta Howells 1,2 , Rachel L. C. Barrett 1,2 , Marco Aiello 4, Carlo Cavaliere 4, Tim B. Dyrby 5,6 , Kristine Krug 7, Maurice Ptito 7,8 , Helen D’Arceuil 9, 10 , Stephanie J. Forkel 1,2*, Flavio Dell’Acqua 1,2*. 1NatBrainLab, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. 2NatBrainLab, Sackler Institute for Translational Neurodevelopment, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. 3Spinal Cord Injury Center, Research, University of Zurich, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich. 4NAPLab, IRCCS SDN Istituto di Ricerca Diagnostica e Nucleare, Via E. Gianturco 113, Naples, Italy, 5 Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. 6 Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kongens Lyngby, Denmark. 7 Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. 8 Laboratory of Neuropsychiatry, PsychiatricMANUSCRIPT Centre Copenhagen, Copenhagen. 9 Ecole d’Optométrie, Université de Montréal, Montréal, Québec. 10 Athinoula A. Martinos Center, Massachusetts General Hospital, Charlestown. * These authors have contributed equally to the study. Corresponding author: Marco Catani, NatBrainLab, PO50 Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK. Email: [email protected] ACCEPTED ACCEPTED MANUSCRIPT ABSTRACT The parietal lobe has a unique place in the human brain. Anatomically, it is at the crossroad between the frontal, occipital, and temporal lobes, thus providing a middle ground for multimodal sensory integration. Functionally, it supports higher cognitive functions that are characteristic of the human species, such as mathematical cognition, semantic and pragmatic aspects of language, and abstract thinking. Despite its importance, a comprehensive comparison of human and simian intraparietal networks is missing. In this study, we used diffusion imaging tractography to reconstruct the major intralobar parietal tracts in twenty-one datasets acquired in vivo from healthy human subjects and eleven ex vivo datasets from five vervet and six macaque monkeys. Three regions of interest (post-central gyrus, superior parietal lobule and inferior parietal lobule) were used to identify the tracts. Surface projections were reconstructed for both species and results compared to identify similarities or differences in tract anatomy (i.e. trajectories and cortical projections). In addition, post-mortem dissections were performed in a human brain. The largest tract identified in both human and monkey brains is a vertical pathway between the superior and inferior parietal lobules. This tract can be divided into an anterior (supramarginal gyrus) and a posterior (angular gyrus) component in both humans and monkey brains. The second prominent intraparietal tract connects the post-central gyrus to both supramaginal and angular gyri of the inferior parietal lobe in humans but only to the supramarginal gyrus in the monkey brain. The third tract connects the post- central gyrus to the anterior region of the MANUSCRIPTsuperior parietal lobule and is more prominent in monkeys compared to humans. Finally, short U-shaped fibres in medial and lateral aspects of the parietal lobe were identified in both species. A tract connecting the medial parietal cortex to the lateral inferior parietal cortex was observed in the monkey brain only. Our findings suggest a consistent pattern of intralobar parietal connections between humans and monkeys with some differences for those areas that have cytoarchitectonically distinct features in humans. The overall pattern of intraparietal connectivity supports the special role of the inferior parietal lobule in cognitive functions characteristic of humans. ACCEPTED ACCEPTED MANUSCRIPT INTRODUCTION Despite proposed functional homologies (Culham & Kanwisher, 2001), studies comparing the anatomy of the human and monkey brain have suggested differences between these two species in some regions of the parietal lobe (Critchley,
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