The Dissociation of Location and Object Working Memory Using Fmri and MEG
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Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans Ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai
Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai To cite this version: Hans ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai. Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex. Frontiers in Neuroanatomy, Frontiers, 2018, 12, pp.93. 10.3389/fnana.2018.00093. hal-01929541 HAL Id: hal-01929541 https://hal.archives-ouvertes.fr/hal-01929541 Submitted on 21 Nov 2018 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. REVIEW published: 19 November 2018 doi: 10.3389/fnana.2018.00093 Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans J. ten Donkelaar 1*†, Nathalie Tzourio-Mazoyer 2† and Jürgen K. Mai 3† 1 Department of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands, 2 IMN Institut des Maladies Neurodégénératives UMR 5293, Université de Bordeaux, Bordeaux, France, 3 Institute for Anatomy, Heinrich Heine University, Düsseldorf, Germany The gyri and sulci of the human brain were defined by pioneers such as Louis-Pierre Gratiolet and Alexander Ecker, and extensified by, among others, Dejerine (1895) and von Economo and Koskinas (1925). -
The Role of the Superior Temporal Sulcus and the Mirror Neuron System in Imitation
r Human Brain Mapping 31:1316–1326 (2010) r The Role of the Superior Temporal Sulcus and the Mirror Neuron System in Imitation Pascal Molenberghs,* Christopher Brander, Jason B. Mattingley, and Ross Cunnington The University of Queensland, Queensland Brain Institute & School of Psychology, St Lucia, Queensland, Australia r r Abstract: It has been suggested that in humans the mirror neuron system provides a neural substrate for imitation behaviour, but the relative contributions of different brain regions to the imitation of manual actions is still a matter of debate. To investigate the role of the mirror neuron system in imita- tion we used fMRI to examine patterns of neural activity under four different conditions: passive ob- servation of a pantomimed action (e.g., hammering a nail); (2) imitation of an observed action; (3) execution of an action in response to a word cue; and (4) self-selected execution of an action. A net- work of cortical areas, including the left supramarginal gyrus, left superior parietal lobule, left dorsal premotor area and bilateral superior temporal sulcus (STS), was significantly active across all four con- ditions. Crucially, within this network the STS bilaterally was the only region in which activity was significantly greater for action imitation than for the passive observation and execution conditions. We suggest that the role of the STS in imitation is not merely to passively register observed biological motion, but rather to actively represent visuomotor correspondences between one’s own actions and the actions of others. Hum Brain Mapp 31:1316–1326, 2010. VC 2010 Wiley-Liss, Inc. Key words: fMRI; imitation; mirror neuron system r r INTRODUCTION ror neurons are visuomotor neurons that fire both when an action is performed and when a similar or identical Motor imitation involves observing the action of another action is passively observed [Rizzolatti and Craighero, individual and matching one’s own movements to those 2004]. -
Efficacy of Transcranial Magnetic Stimulation Targets for Depression
Efficacy of Transcranial Magnetic Stimulation Targets for Depression Is Related to Intrinsic Functional Connectivity with the Subgenual Cingulate Michael D. Fox, Randy L. Buckner, Matthew P. White, Michael D. Greicius, and Alvaro Pascual-Leone Background: Transcranial magnetic stimulation (TMS) to the left dorsolateral prefrontal cortex (DLPFC) is used clinically for the treatment of depression. However, the antidepressant mechanism remains unknown and its therapeutic efficacy remains limited. Recent data suggest that some left DLPFC targets are more effective than others; however, the reasons for this heterogeneity and how to capitalize on this information remain unclear. Methods: Intrinsic (resting state) functional magnetic resonance imaging data from 98 normal subjects were used to compute functional connectivity with various left DLPFC TMS targets employed in the literature. Differences in functional connectivity related to differences in previously reported clinical efficacy were identified. This information was translated into a connectivity-based targeting strategy to identify optimized left DLPFC TMS coordinates. Results in normal subjects were tested for reproducibility in an independent cohort of 13 patients with depression. Results: Differences in functional connectivity were related to previously reported differences in clinical efficacy across a distributed set of cortical and limbic regions. Dorsolateral prefrontal cortex TMS sites with better clinical efficacy were more negatively correlated (anticorre- lated) with the subgenual cingulate. Optimum connectivity-based stimulation coordinates were identified in Brodmann area 46. Results were reproducible in patients with depression. Conclusions: Reported antidepressant efficacy of different left DLPFC TMS sites is related to the anticorrelation of each site with the subgenual cingulate, potentially lending insight into the antidepressant mechanism of TMS and suggesting a role for intrinsically anticor- related networks in depression. -
Translingual Neural Stimulation with the Portable Neuromodulation
Translingual Neural Stimulation With the Portable Neuromodulation Stimulator (PoNS®) Induces Structural Changes Leading to Functional Recovery In Patients With Mild-To-Moderate Traumatic Brain Injury Authors: Jiancheng Hou,1 Arman Kulkarni,2 Neelima Tellapragada,1 Veena Nair,1 Yuri Danilov,3 Kurt Kaczmarek,3 Beth Meyerand,2 Mitchell Tyler,2,3 *Vivek Prabhakaran1 1. Department of Radiology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA 2. Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA 3. Department of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA *Correspondence to [email protected] Disclosure: Dr Tyler, Dr Danilov, and Dr Kaczmarek are co-founders of Advanced Neurorehabilitation, LLC, which holds the intellectual property rights to the PoNS® technology. Dr Tyler is a board member of NeuroHabilitation Corporation, a wholly- owned subsidiary of Helius Medical Technologies, and owns stock in the corporation. The other authors have declared no conflicts of interest. Acknowledgements: Professional medical writing and editorial assistance were provided by Kelly M. Fahrbach, Ashfield Healthcare Communications, part of UDG Healthcare plc, funded by Helius Medical Technologies. Dr Tyler, Dr Kaczmarek, Dr Danilov, Dr Hou, and Dr Prabhakaran were being supported by NHC-TBI-PoNS-RT001. Dr Hou, Dr Kulkarni, Dr Nair, Dr Tellapragada, and Dr Prabhakaran were being supported by R01AI138647. Dr Hou and Dr Prabhakaran were being supported by P01AI132132, R01NS105646. Dr Kulkarni was being supported by the Clinical & Translational Science Award programme of the National Center for Research Resources, NCATS grant 1UL1RR025011. Dr Meyerand, Dr Prabhakaran, Dr Nair was being supported by U01NS093650. -
The Prefrontal Cortex
Avens Publishing Group Inviting Innovations Open Access Review Article J Hum Anat Physiol July 2017 Volume:1, Issue:1 © All rights are reserved by Ogeturk. AvensJournal Publishing of Group Inviting Innovations Human Anatomy The Prefrontal Cortex: A Basic & Physiology Embryological, Histological, Anatomical, and Functional Ramazan Fazıl Akkoc and Murat Ogeturk* Department of Anatomy, Firat University, Turkey Guideline *Address for Correspondence Murat Ogeturk, Firat University, Faculty of Medicine, 23119 Elazig, Turkey, Tel: +90-424-2370000 (ext: 4654); Fax: +90-424-2379138; Keywords: Prefrontal cortex; Working memory; Frontal lobe E-Mail: [email protected] Abstract Submission: 24 May, 2017 Accepted: 11 July, 2017 The prefrontal cortex (PFC) unites, processes and controls the Published: 19 August, 2017 information coming from cortex and subcortical structures, and Copyright: © 2017 Akkoc RF. This is an open access article distributed decides and executes goal-oriented behavior. A major function of PFC under the Creative Commons Attribution License, which permits is to maintain the attention. Furthermore, it has many other functions unrestricted use, distribution, and reproduction in any medium, provided including working memory, problem solving, graciousness, memory, the original work is properly cited. and intellectuality. PFC is well developed in humans and localized to the anterior of the frontal lobe. This article presents a systematic review and detailed summary of embryology, histology, anatomy, functions and lesions of PFC. I. Lamina zonalis: Contains few Cajal horizontal cells. The axons of Martinotti cells located at deep layers, the last branches of the apical dendrites of pyramidal cells, and the last branches Introduction of the afferent nerve fibers extend to this lamina. -
An Analysis of Functional Neuroimaging Studies of Dorsolateral Prefrontal Cortical Activity in Depression
Psychiatry Research: Neuroimaging 148 (2006) 33–45 www.elsevier.com/locate/psychresns An analysis of functional neuroimaging studies of dorsolateral prefrontal cortical activity in depression Paul B. Fitzgeralda,⁎, Tom J. Oxleya, Angela R. Lairdb, Jayashri Kulkarnia, Gary F. Eganc, Zafiris J. Daskalakisd aAlfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd, Melbourne, Victoria 3004, Australia bResearch Imaging Center, The University of Texas Health Science Center, San Antonio, San Antonio, TX, USA cHoward Florey Institute, The University of Melbourne, Victoria, Australia dCentre for Addiction and Mental Health, Clarke Division, Toronto, Ontario, Canada Received 22 December 2005; received in revised form 28 March 2006; accepted 10 April 2006 Abstract Repetitive transcranial magnetic stimulation (rTMS) is currently undergoing active investigation for use in the treatment of major depression. Recent research has indicated that current methods used to localize the site of stimulation in dorsolateral prefrontal cortex (DLPFC) are significantly inaccurate. However, little information is available on which to base a choice of stimulation site. The aim of the current study was to systematically examine imaging studies in depression to attempt to identify whether there is a pattern of imaging results that suggests an optimal site of stimulation localization. We analysed all imaging studies published prior to 2005 that examined patients with major depression. Studies reporting activation in DLPFC were identified. The DLPFC regions identified in these studies were analysed using the Talairach and Rajkowska–Goldman-Rakic coordinate systems. In addition, we conducted a quantitative meta-analysis of resting studies and studies of serotonin reuptake inhibitor antidepressant treatment. -
Potential Scalp Stimulation Targets for Mental Disorders
Cao et al. J Transl Med (2021) 19:343 https://doi.org/10.1186/s12967-021-02993-1 Journal of Translational Medicine RESEARCH Open Access Potential scalp stimulation targets for mental disorders: evidence from neuroimaging studies Jin Cao, Thalia Celeste Chai‑Zhang, Yiting Huang, Maya Nicole Eshel and Jian Kong* Abstract Mental disorders widely contribute to the modern global disease burden, creating a signifcant need for improvement of treatments. Scalp stimulation methods (such as scalp acupuncture and transcranial electrical stimulation) have shown promising results in relieving psychiatric symptoms. However, neuroimaging fndings haven’t been well‑ integrated into scalp stimulation treatments. Identifying surface brain regions associated with mental disorders would expand target selection and the potential for these interventions as treatments for mental disorders. In this study, we performed large‑scale meta‑analyses separately on eight common mental disorders: attention defcit hyperactivity disorder, anxiety disorder, autism spectrum disorder, bipolar disorder, compulsive disorder, major depression, post‑ traumatic stress disorder and schizophrenia; utilizing modern neuroimaging literature to summarize disorder‑asso‑ ciated surface brain regions, and proposed neuroimaging‑based target protocols. We found that the medial frontal gyrus, the supplementary motor area, and the dorsal lateral prefrontal cortex are commonly involved in the patho‑ physiology of mental disorders. The target protocols we proposed may provide new brain targets for scalp stimulation in the treatment of mental disorders, and facilitate its clinical application. Keywords: Neuroimaging, Meta‑analysis, Scalp stimulation, Scalp acupuncture, Transcranial electrical stimulation, Mental disorder Introduction For instance, scalp acupuncture, a modern school of Mental disorders are a major component of the modern acupuncture developed on the basis of anatomical and global disease burden. -
Non-Invasive Brain Stimulation of the Posterior Parietal Cortex Alters Postural Adaptation
ORIGINAL RESEARCH published: 26 June 2020 doi: 10.3389/fnhum.2020.00248 Non-invasive Brain Stimulation of the Posterior Parietal Cortex Alters Postural Adaptation David R. Young 1*, Pranav J. Parikh 1 and Charles S. Layne 1,2 1Center for Neuromotor and Biomechanics Research, Department of Health and Human Performance, University of Houston, Houston, TX, United States, 2Center for Neuro-Engineering and Cognitive Science, University of Houston, Houston, TX, United States Effective central sensory integration of visual, vestibular, and proprioceptive information is required to promote adaptability in response to changes in the environment during postural control. Patients with a lesion in the posterior parietal cortex (PPC) have an impaired ability to form an internal representation of body position, an important factor for postural control and adaptation. Suppression of PPC excitability has also been shown to decrease postural stability in some contexts. As of yet, it is unknown whether stimulation of the PPC may influence postural adaptation. This investigation aimed to identify whether transcranial direct current stimulation (tDCS) of the bilateral PPC could modulate postural adaptation in response to a bipedal incline postural Edited by: adaptation task. Using young, healthy subjects, we delivered tDCS over bilateral PPC Giovanni Di Pino, Campus Bio-Medico University, Italy followed by bouts of inclined stance (incline-interventions). Analysis of postural after- effects identified differences between stimulation conditions for maximum lean after- Reviewed by: Junhong Zhou, effect (LAE; p = 0.005) as well as a significant interaction between condition and Harvard Medical School, measurement period for the average position (p = 0.03). We identified impaired postural United States Leif Johannsen, adaptability following both active stimulation conditions. -
1. Lateral View of Lobes in Left Hemisphere TOPOGRAPHY
TOPOGRAPHY T1 Division of Cerebral Cortex into Lobes 1. Lateral View of Lobes in Left Hemisphere 2. Medial View of Lobes in Right Hemisphere PARIETAL PARIETAL LIMBIC FRONTAL FRONTAL INSULAR: buried OCCIPITAL OCCIPITAL in lateral fissure TEMPORAL TEMPORAL 3. Dorsal View of Lobes 4. Ventral View of Lobes PARIETAL TEMPORAL LIMBIC FRONTAL OCCIPITAL FRONTAL OCCIPITAL Comment: The cerebral lobes are arbitrary divisions of the cerebrum, taking their names, for the most part, from overlying bones. They are not functional subdivisions of the brain, but serve as a reference for locating specific functions within them. The anterior (rostral) end of the frontal lobe is referred to as the frontal pole. Similarly, the anterior end of the temporal lobe is the temporal pole, and the posterior end of the occipital lobe the occipital pole. TOPOGRAPHY T2 central sulcus central sulcus parietal frontal occipital lateral temporal lateral sulcus sulcus SUMMARY CARTOON: LOBES SUMMARY CARTOON: GYRI Lateral View of Left Hemisphere central sulcus postcentral superior parietal superior precentral gyrus gyrus lobule frontal intraparietal sulcus gyrus inferior parietal lobule: supramarginal and angular gyri middle frontal parieto-occipital sulcus gyrus incision for close-up below OP T preoccipital O notch inferior frontal cerebellum gyrus: O-orbital lateral T-triangular sulcus superior, middle and inferior temporal gyri OP-opercular Lateral View of Insula central sulcus cut surface corresponding to incision in above figure insula superior temporal gyrus Comment: Insula (insular gyri) exposed by removal of overlying opercula (“lids” of frontal and parietal cortex). TOPOGRAPHY T3 Language sites and arcuate fasciculus. MRI reconstruction from a volunteer. central sulcus supramarginal site (posterior Wernicke’s) Language sites (squares) approximated from electrical stimulation sites in patients undergoing operations for epilepsy or tumor removal (Ojeman and Berger). -
Altered Brain Activation During Action Imitation and Observation in Schizophrenia: a Translational Approach to Investigating Social Dysfunction in Schizophrenia
Article Altered Brain Activation During Action Imitation and Observation in Schizophrenia: A Translational Approach to Investigating Social Dysfunction in Schizophrenia Katharine N. Thakkar, Ph.D. Objective: Social impairments are a key Results: Activation in the mirror neuron feature of schizophrenia, but their un- system was less specific for imitation in Joel S. Peterman, M.A. derlying mechanisms are poorly under- schizophrenia. Relative to healthy sub- stood. Imitation, a process through which jects, patients had reduced activity in the Sohee Park, Ph.D. we understand the minds of others, posterior superior temporal sulcus dur- involves the so-called mirror neuron sys- ing imitation and greater activity in the tem, a network comprising the inferior posterior superior temporal sulcus and parietal lobe, inferior frontal gyrus, and inferior parietal lobe during nonimita- posterior superior temporal sulcus. The tive action. Patients also showed reduced authors examined mirror neuron system activity in these regions during action function in schizophrenia. observation. Mirror neuron system ac- tivation was related to symptom severity Method: Sixteen medicated schizophre- and social functioning in patients and nia patients and 16 healthy comparison to schizotypal syndrome in comparison subjects performed an action imitation/ subjects. observation task during functional MRI. Participants saw a video of a moving hand Conclusions: Given the role of the in- or spatial cue and were instructed to either ferior parietal lobe and posterior superior execute finger movements associated with temporal sulcus in imitation and social the stimulus or simply observe. Activation cognition, impaired imitative ability in in the mirror neuron system was measured schizophrenia may stem from faulty during imitative versus nonimitative perception of biological motion and trans- actions and observation of a moving hand formations from perception to action. -
Supplementary Tables
Supplementary Tables: ROI Atlas Significant table grey matter Test ROI # Brainetome area beta volume EG pre vs post IT 8 'superior frontal gyrus, part 4 (dorsolateral area 6), right', 0.773 17388 11 'superior frontal gyrus, part 6 (medial area 9), left', 0.793 18630 12 'superior frontal gyrus, part 6 (medial area 9), right', 0.806 24543 17 'middle frontal gyrus, part 2 (inferior frontal junction), left', 0.819 22140 35 'inferior frontal gyrus, part 4 (rostral area 45), left', 1.3 10665 67 'paracentral lobule, part 2 (area 4 lower limb), left', 0.86 13662 EG pre vs post ET 20 'middle frontal gyrus, part 3 (area 46), right', 0.934 28188 21 'middle frontal gyrus, part 4 (ventral area 9/46 ), left' 0.812 27864 31 'inferior frontal gyrus, part 2 (inferior frontal sulcus), left', 0.864 11124 35 'inferior frontal gyrus, part 4 (rostral area 45), left', 1 10665 50 'orbital gyrus, part 5 (area 13), right', -1.7 22626 67 'paracentral lobule, part 2 (area 4 lower limb), left', 1.1 13662 180 'cingulate gyrus, part 3 (pregenual area 32), right', 0.9 10665 261 'Cerebellar lobule VIIb, vermis', -1.5 729 IG pre vs post IT 16 middle frontal gyrus, part 1 (dorsal area 9/46), right', -0.8 27567 24 'middle frontal gyrus, part 5 (ventrolateral area 8), right', -0.8 22437 40 'inferior frontal gyrus, part 6 (ventral area 44), right', -0.9 8262 54 'precentral gyrus, part 1 (area 4 head and face), right', -0.9 14175 64 'precentral gyrus, part 2 (caudal dorsolateral area 6), left', -1.3 18819 81 'middle temporal gyrus, part 1 (caudal area 21), left', -1.4 14472 -
Quasi-Periodic Patterns Contribute to Functional Connectivity in the Brain
bioRxiv preprint doi: https://doi.org/10.1101/323162; this version posted May 16, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Quasi-periodic patterns contribute to functional connectivity in the brain Anzar Abbasa, Michaël Belloyb, Amrit Kashyapc, Jacob Billingsa, Maysam Nezafatic, Shella Keilholza,c a Neuroscience, Emory University, 1760 Haygood Dr NE Suite W-200, Atlanta, GA 30322, United States b Bio-Imaging Lab, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium c Biomedical Engineering, Emory University and Georgia Institute of Technology, 1760 Haygood Dr NE Suite W-200, Atlanta, GA 30322, United States Corresponding Author Shella Keilholz [email protected] 1760 Haygood Dr NE W-230 Atlanta, GA 30322 Highlights • Quasi-periodic patterns (QPPs) of low-frequency activity contribute to functional connectivity • The spatiotemporal pattern of QPPs differs between resting-state and task-performing individuals • QPPs account for significant functional connectivity in the DMN and TPN during rest and task performance • Changes in functional connectivity in these networks may actually reflect differences in the QPPs Declarations of Interest None !1 bioRxiv preprint doi: https://doi.org/10.1101/323162; this version posted May 16, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license.