Integrating Research Integrity Into the History of Science
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Case Studies in Research Misconduct and Human Subjects
Rules of the Road for those Conducting Federally Funded or Regulated Research: Case Studies in Research Misconduct and Human Subjects April 2, 2019 University of Maryland School of Medicine Baltimore, MD Robert P. Charrow General Counsel United States Department of Health and Human Services Introduction The materials that follow address three areas-misconduct in science, human subjects and privacy, and financial conflicts of interest. To help illustrate the application of the rules that pertain in each area, a number of hypothetical case studies are presented. You should read and be prepared to discuss each case study during the April 2 lecture. The government regulates research under two authorities. First, it regulates research that it funds. How much does the federal government spend annually on research? See Table 2. Second, a federal agency can regulate research on products that fall within its jurisdiction. Thus, by way of example, the Food and Drug Administration asserts jurisdiction over clinical drug trials even though those trials are privately funded. 1. Misconduct A. What is Research Misconduct? The Public Health Service ("PHS"), which includes NIH, defines "research misconduct" as follows: Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results. (a) Fabrication is making up data or results and recording or reporting them. (b) Falsification is manipulating research materials, equipment, or processes, or changing or omitting data or results such that the research is not accurately represented in the research record. (c) Plagiarism is the appropriation of another person's ideas, processes, results, or words without giving appropriate credit. -
Integrating the History of Science Into Broader Discussions of Research Integrity and Fraud
HOS0010.1177/0073275320952268History of ScienceRoberts et al. 952268research-article2020 Introduction HOS History of Science 2020, Vol. 58(4) 354 –368 Integrating the history © The Author(s) 2020 of science into broader https://doi.org/10.1177/0073275320952268Article reuse guidelines: sagepub.com/journals-permissions discussions of research DOI: 10.1177/0073275320952268 integrity and fraud journals.sagepub.com/home/hos Lissa L. Roberts University of Twente, Netherlands H. Otto Sibum Uppsala University, Sweden Cyrus C. M. Mody Maastricht University, Netherlands Abstract This introductory article frames our special issue in terms of how historicizing research integrity and fraud can benefit current discussions of scientific conduct and the need to improve public trust in science. Keywords Research integrity, fraud, scientific conduct, scientific values, public trust Writing about research integrity and fraud in the midst of the Covid-19 crisis carries an extra sense of urgency. Voices of reason tell us to trust the experts, echoing both the (idealized) scientific method and Ronald Reagan’s response to Soviet promises regard- ing nuclear disarmament: “trust, but verify.” Great advice, but how easy is it really to identify trustworthy experts? Is the boundary between healthy skepticism and manufac- tured doubt a simple matter of distinguishing between valid laboratory and publishing protocols on one side and political, economic, or personal interests on the other? Should we follow those who rely on the Mertonian distinction between norm-bound -
Achieving a High Level of Protection from Pesticides in Europe: Problems with the Current Risk Assessment Procedure and Solutions
https://doi.org/10.1017/err.2020.18 . Achieving a High Level of Protection from Pesticides in Europe: Problems with the Current Risk Assessment Procedure and Solutions Claire ROBINSON* , Christopher J. PORTIER**, Aleksandra ČAVOŠKI***, Robin MESNAGE****, Apolline ROGER*****, Peter CLAUSING******, Paul WHALEY*******, Hans MUILERMAN******** and https://www.cambridge.org/core/terms Angeliki LYSSIMACHOU********* The regulation of pesticides in the European Union (EU) relies on a network of hard law (legislation and implementing acts) and soft law (non-legally binding guidance documents and administrative and scientific practices). Both hard and soft laws govern how risk assessments are conducted, but a significant role is left to the latter. Europe’s pesticide regulation is one of the most stringent in the world. Its stated objectives are to ensure an independent, objective and transparent assessment of pesticides and achieve a high level of protection for health and environment. However, a growing body of evidence shows that pesticides that have passed through this process and are authorised for use may harm , subject to the Cambridge Core terms of use, available at humans, animals and the environment. The authors of the current paper – experts in toxicology, law and policy – identified shortcomings in the authorisation process, focusing on the EU assessment of the pesticide active substance glyphosate. The shortcomings mostly consist of failures to implement the hard or soft laws. But in some instances the law itself is responsible, as some provisions can only fail to achieve its objectives. Ways to improve the system are proposed, requiring changes in hard and soft laws as well as in administrative 30 Sep 2021 at 13:44:58 and scientific practices. -
“Technologies of the Law/ Law As a Technology”
HOS0010.1177/0073275318816163History of ScienceBiagioli and Buning 816163research-article2018 Special Issue - Technologies of the Law/ Law as a Technology HOS History of Science 1 –15 “Technologies of the © The Author(s) 2018 Article reuse guidelines: law/ law as a technology” sagepub.com/journals-permissions https://doi.org/10.1177/0073275318816163DOI: 10.1177/0073275318816163 journals.sagepub.com/home/hos Mario Biagioli UC Davis, USA Marius Buning Freie Universitat, Berlin, Germany Abstract Historians of science and technology and STS practitioners have always taken intellectual property very seriously but, with some notable exceptions, they have typically refrained from looking “into” it. There is mounting evidence, however, that they can open up the black box of IP as effectively as they have done for the technosciences, enriching their discipline while making significant contributions to legal studies. One approach is to look at the technologies through which patent law construes its object – the invention – in specific settings and periods by examining procedures, classifications, archives, models, repositories, patent specifications (in both their linguistic and pictorial dimensions), and the highly specialized language of patent claims. More ambitiously, we could treat intellectual property as a technology itself. Patent law does not evolve either by merely articulating its doctrine in response to technological developments. The line between what does and does not count as invention may be redrawn with the emergence of new objects and technologies, but is not determined by them. It is this constructive feature of the law that we are trying to capture with the notion of law as technology. We hope that thinking about the technologies of the law and the law as technology will bring into question what we mean by both “technology” and “law”. -
ELCOCK-DISSERTATION.Pdf
HIGH NEW YORK THE BIRTH OF A PSYCHEDELIC SUBCULTURE IN THE AMERICAN CITY A Thesis Submitted to the College of Graduate Studies and Research in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in the Department of History University of Saskatchewan Saskatoon By CHRIS ELCOCK Copyright Chris Elcock, October, 2015. All rights reserved Permission to Use In presenting this thesis in partial fulfilment of the requirements for a Postgraduate degree from the University of Saskatchewan, I agree that the Libraries of this University may make it freely available for inspection. I further agree that permission for copying of this thesis in any manner, in whole or in part, for scholarly purposes may be granted by the professor or professors who supervised my thesis work or, in their absence, by the Head of the Department or the Dean of the College in which my thesis work was done. It is understood that any copying or publication or use of this thesis or parts thereof for financial gain shall not be allowed without my written permission. It is also understood that due recognition shall be given to me and to the University of Saskatchewan in any scholarly use which may be made of any material in my thesis. Requests for permission to copy or to make other use of material in this thesis in whole or part should be addressed to: Head of the Department of History Room 522, Arts Building 9 Campus Drive University of Saskatchewan Saskatoon, Saskatchewan S7N 5A5 Canada i ABSTRACT The consumption of LSD and similar psychedelic drugs in New York City led to a great deal of cultural innovations that formed a unique psychedelic subculture from the early 1960s onwards. -
On Speed: the Many Lives of Amphetamine
On Speed Nicolas Rasmussen On Speed The Many Lives of Amphetamine a New York University Press • New York and London NEW YORK UNIVERSITY PRESS New York and London www.nyupress.org © 2008 by New York University All rights reserved Library of Congress Cataloging-in-Publication Data Rasmussen, Nicolas, 1962– On speed : the many lives of amphetamine / Nicolas Rasmussen. p. ; cm. Includes bibliographical references and index. ISBN-13: 978-0-8147-7601-8 (cl : alk. paper) ISBN-10: 0-8147-7601-9 (cl : alk. paper) 1. Amphetamines—United States—History. 2. Amphetamine abuse— United States—History. I. Title. II. Title: Many lives of amphetamine. [DNLM: 1. Amphetamines—history—United States. 2. Amphetamine-Related Disorders—history—United States. 3. History, 20th Century—United States. 4. History, 21st Century—United States. QV 102 R225o 2007] RM666.A493R37 2007 362.29'90973—dc22 2007043261 New York University Press books are printed on acid-free paper, and their binding materials are chosen for strength and durability. Manufactured in the United States of America c10987654321 p10987654321 To my parents, Laura and Norman, for teaching me to ask questions Contents Acknowledgments ix Introduction 1 1 The New Sensation 6 2 Benzedrine: The Making of a Modern Medicine 25 3 Speed and Total War 53 4 Bootleggers, Beatniks, and Benzedrine Benders 87 5 A Bromide for the Atomic Age 113 6 Amphetamine and the Go-Go Years 149 7 Amphetamine’s Decline: From Mental Medicine to Social Disease 182 8 Fast Forward: Still on Speed, 1971 to Today 222 Conclusion: The Lessons of History 255 Notes 261 List of Archival Sources 347 Index 348 About the Author 352 Illustrations appear in two groups following pages 86 and 148. -
Springer International Publishing AG, Part of Springer Nature 2018 1 M
Biomedicine and Its Historiography: A Systematic Review Nicolas Rasmussen Contents Introduction ....................................................................................... 1 What Is Biomedicine? ............................................................................ 2 Biomedicine’s Postwar Development ............................................................ 7 The Distribution of Activity in Biomedicine and in Its Historiography . ...................... 14 Conclusion ........................................................................................ 19 References ........................................................................................ 20 Abstract In this essay I conduct a quantitative systematic review of the scholarly literature in history of life sciences, assessing how well the distribution of the activity of historians aligns with the distribution of activities of scientists across fields of biomedical research as defined by expenditures by the cognate institutes of the United States NIH. I also ask how well the distribution of resources to the various research fields of biomedicine in the second half of the 20th Century has aligned with morbidity and mortality in the United States associated with the cognate disease categories. The two exercises point to underexplored areas for historical work, and open new historical questions about research policy in the US. Introduction I have taken an unusual approach in this essay to ask a question that, to my knowledge, has not been addressed before: how -
Managing Allegations of Scientific Misconduct: A
MANAGING ALLEGATIONS OF SCIENTIFIC MISCONDUCT: A Guidance Document for Editors January 2000 Office of Research Integrity Office of Public Health and Science U.S. Department of Health and Human Services http://ori.dhhs.gov 1 TABLE OF CONTENTS I. Role of Editors in Responding to Scientific Misconduct .............. 1 II. Purpose of Guidelines ................................................................... 2 III. Definitions ..................................................................................... 2 IV. Procedure for Handling Suspect Manuscripts .............................. 3 V. Responding to ORI Requests for Assistance ............................... 4 VI. Correcting the Literature ............................................................... 5 VII. Helpful Editorial Policies ............................................................... 5 VIII. Conclusion .................................................................................... 8 References ................................................................................................. 9 Appendix A: ORI Case Examples of Suspect Manuscripts ..................... 11 ORI Information and Technical Assistance . Inside Back Cover 2 MANAGING ALLEGATIONS OF SCIENTIFIC MISCONDUCT: A Guidance Document for Editors* I. Role of Editors in Responding to Scientific Misconduct The role editors should play in responding to scientific misconduct has been articulated by their colleagues, asserted by two national reports, and demonstrated by the scientific misconduct allegations -
How Scientific Misconduct Harms Prior Collaborators
A Service of Leibniz-Informationszentrum econstor Wirtschaft Leibniz Information Centre Make Your Publications Visible. zbw for Economics Hussinger, Katrin; Pellens, Maikel Working Paper Guilt by association: How scientific misconduct harms prior collaborators ZEW Discussion Papers, No. 17-051 Provided in Cooperation with: ZEW - Leibniz Centre for European Economic Research Suggested Citation: Hussinger, Katrin; Pellens, Maikel (2017) : Guilt by association: How scientific misconduct harms prior collaborators, ZEW Discussion Papers, No. 17-051, Zentrum für Europäische Wirtschaftsforschung (ZEW), Mannheim, http://nbn-resolving.de/urn:nbn:de:bsz:180-madoc-436888 This Version is available at: http://hdl.handle.net/10419/171327 Standard-Nutzungsbedingungen: Terms of use: Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Documents in EconStor may be saved and copied for your Zwecken und zum Privatgebrauch gespeichert und kopiert werden. personal and scholarly purposes. Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle You are not to copy documents for public or commercial Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich purposes, to exhibit the documents publicly, to make them machen, vertreiben oder anderweitig nutzen. publicly available on the internet, or to distribute or otherwise use the documents in public. Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, If the documents have been made available under an Open gelten abweichend von diesen Nutzungsbedingungen die in der dort Content Licence (especially Creative Commons Licences), you genannten Lizenz gewährten Nutzungsrechte. may exercise further usage rights as specified in the indicated licence. www.econstor.eu Dis cus si on Paper No. 17-051 Guilt by Association: How Scientific Misconduct Harms Prior Collaborators Katrin Hussinger and Maikel Pellens Dis cus si on Paper No. -
June 11-14, 2011 Snow King Resort Jackson Hole, Wyoming
PROGRAM BOOK JUNE 11-14, 2011 SNOW KING RESORT JACKSON HOLE, WYOMING CHILDREN’S TUMOR FOUNDATION 95 PINE STREET, 16TH FLOOR, NEW YORK, NY 10005 | WWW.CTF.ORG | 212.344.6633 Dear NF Conference Attendees: On behalf of the Children’s Tumor Foundation, welcome to the 2011 NF Conference. Yes we are back in the mountains! Those NF ‘historians’ among us will remember that until 2006 this meeting was held at the Hotel Jerome in Aspen, Colorado. We know many of you loved that mountain setting, and recall with fondness the time when you knew everyone at the meeting personally, every afternoon was totally free, and everyone could fit onto the Jerome’s terrace for the farewell dinner. Those early meetings were special and those of you who took part were the pioneers who laid the founding stones of NF research. We outgrew the Hotel Jerome in 2007, as meeting attendance grew from 140 in 2005 to over 300 in 2010. What happened? In short, NF research progress happened. We are no longer speculating about NF clinical trials – they are underway. As of this spring, 19 NF specific trials were listed on clinicaltrials.gov. This is incredible progress. The NF Conference remains the foremost venue for world-class discussion on NF biology. But it is now also now a forum for the clinicians to discuss ongoing NF trials, and to collaborate with the scientists as to the next drugs they should consider. The meeting agenda has expanded to accommodate these new developments in our search to unlock the mysteries of NF. -
Download Preprint
Recommendations from the Reducing the Inadvertent Spread of Retracted Science: Shaping a Research and Implementation Agenda Project Jodi Schneider*, Nathan D. Woods, Randi Proescholdt, Yuanxi Fu, and the RISRS Team July 2021 *Corresponding author: [email protected] and [email protected] Table of Contents EXECUTIVE SUMMARY 3 Recommendations 4 INTRODUCTION 5 RISRS Project Goals and Assumptions 6 Framing the Problem 8 Scope of this Document 9 THE RISRS PROCESS 10 Scoping Literature Review 10 Interviews 11 Workshop, Dissemination, and Implementation 11 LITERATURE REVIEW AND CURRENT AWARENESS 11 Reasons for Retraction 11 Formats and Types of Retraction 13 Field Variation 15 Continued Citation of Retracted Papers: What Went Wrong? 20 Visibility of Retraction Status 24 Inconsistent Retraction Metadata 25 Quality of Retraction Notices 26 Literature Review Conclusions 28 DEFINING PROBLEMS AND OPPORTUNITIES 29 PROBLEMS AND OPPORTUNITIES DESCRIBED BY THE EMPIRICAL LITERATURE ON RETRACTION 29 Problem Themes Described by the Empirical Literature on Retraction 30 Opportunity Themes Described by the Empirical Literature on Retraction 32 Problem Definition Described by the Empirical Literature on Retraction 35 THEMES FROM STAKEHOLDER INTERVIEWS 36 Problem Frameworks based on Stakeholder Interviews 36 Contentious Themes based on Stakeholder Interviews 38 The Purpose of Retraction According to Stakeholder Interviews 38 Changing the Scholarly Record 39 The Harms of Retraction According to Stakeholder Interviews 39 The Character of Reform According to Stakeholder Interviews 40 SYNTHESIZING THE PROBLEMS AND OPPORTUNITIES 41 Aligning Opportunity Pathways 41 Defining the Scale and Scope of the Problem 42 RECOMMENDATIONS 43 1. Develop a Systematic Cross-industry Approach to Ensure the Public Availability of Consistent, Standardized, Interoperable, and Timely Information about Retractions. -
Parallels of Unintentional Plagiarism and Predatory Publishing: Understanding Root Causes and Solutions
City University of New York (CUNY) CUNY Academic Works Publications and Research New York City College of Technology 2017 Parallels of Unintentional Plagiarism and Predatory Publishing: Understanding Root Causes and Solutions Monica Berger CUNY New York City College of Technology How does access to this work benefit ou?y Let us know! More information about this work at: https://academicworks.cuny.edu/ny_pubs/352 Discover additional works at: https://academicworks.cuny.edu This work is made publicly available by the City University of New York (CUNY). Contact: [email protected] Monica Berger, Associate Professor, Library, NYC College of Technology, CUNY Parallels of Unintentional Plagiarism and Predatory Publishing: Understanding Root Causes and Solutions CUNY-Wide Conference on Academic Integrity Eugenio María de Hostos Community College Sept. 29, 2017 Abstract Plagiarism and predatory publishing share common attributes. Although students do not publish in predatory journals, both plagiarism and predatory publishing fall under the umbrella of academic integrity and scholarly ethics. Academic misconduct has many faces, ranging from student cheating on exams to purchasing a doctoral thesis and claiming it as one’s own work. Some forms of academic misconduct, such as the examples above are always intentional. However, many manifestations of academic misconduct are less clearly intentional. Students often plagiarize unintentionally because they lack writing skills including paraphrasing and citing. Faculty sometimes publish with predatory journals when they lack scholarly publishing knowledge. Weak information literacy underpins both behaviors. However, other factors drive both plagiarism and predatory publishing. Three broad areas are cultural considerations, generational differences, and local academic values. The discourse related to cultural considerations is especially fruitful to unpack.