THE STATE OF SÃO PAULO RESEARCH FOUNDATION

Translating Research into Business

Ten years promoting technological innovation THE STATE OF SÃO PAULO RESEARCH FOUNDATION

Carlos Vogt President

Marcos Macari Vice-president

BOARD OF TRUSTEES Adilson Avansi de Abreu Carlos Vogt Celso Lafer Hermann Wever Horácio Lafer Piva Hugo Aguirre Armelin José Arana Varela Marcos Macari Nilson Dias Vieira Júnior Vahan Agopyan Yoshiaki Nakano

EXECUTIVE BOARD Ricardo Renzo Brentani Chief Executive

Carlos Henrique de Brito Cruz Scientific Director

Joaquim José de Camargo Engler Administrative Director Translating Research into Business

Ten years promoting technological innovation

Projects supported by FAPESP in the Partnership for Technological Innovation and Technological Innovation in Small Businesses Programs

2005 Catalogação-na-publicação elaborada pelo Centro de Documentação e Informação da FAPESP

The State of São Paulo Research Foundation. Translating research into business : ten years promoting technological innovation : projects supported by FAPESP in the Partnership for Technological Innovation and Technological Innovation in Small Businesses programs / The State of São Paulo Research Foundation – São Paulo : FAPESP, 2005. 256 p. : il. ; 28 cm.

Tradução de: A pesquisa traduzida em negócios : dez anos de incentivo à inovação tecnológica : projetos apoiados pela FAPESP nos programas Parceria para Inovação Tecnológica e Inovação Tecnológica em Pequenas Empresas.

I. Título II. Título: Ten years promoting technological innovation. III. Título: Projects supported by FAPESP in the Partnership for Technological Innovation and Technological Innovation in Small Businesses programs. 1.FAPESP 2. Pesquisa e desenvolvimento – São Paulo 3. Ciência 4. Tecnologia 5. Inovação tecnológica 6. Inovação Tecnológica em Pequenas Empresas 7. PIPE 8. Parceria para Inovação Tecnológica 9. PITE

04/05 CDD 507.208161 Depósito Legal na Biblioteca Nacional, conforme Lei n.º 10.994, de 14 de dezembro de 2004.

2005 Direitos reservados à FAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo Rua Pio XI, 1500 – Alto da Lapa 05468-901 – São Paulo – SP Tel: (11) 3838-4000 Advancement of Knowledge with Development of the Economy

ver the last 50 years, Brazil has developed a competitive academic capability in the activities of the advancement of knowledge and the training of human O resources. There has been a six-fold increase in scientific production since 1980 – a rate of growth well above the world average –, whilst the highly suc- cessful state drive to support post-graduates over this period nowadays enables the qual- ification of 9 thousand new PhDs each year. All of this indicates the existence of an aca- demic base comparable to that of many member countries of the Organization for Cooperation and Economic Development (OCDE), which derives from the complemen- tary drive of research support agencies such as the National Council for Scientific and Technological Development (CNPq), the Coordination for the Training of University Personnel (Capes), the Financier of Studies and Projects (Finep) and from state research support foundations including the State of São Paulo Research Foundation (FAPESP). This base enables the country to meet with increased chances of success, the enormous challenge of introducing research activity into businesses, bringing an increase in tech- nological competitiveness and in the capacity for innovation. FAPESP, one of the main support agencies for scientific and technological research in Brazil, has played a key role in this endeavor to engage the academic base by means of the training of human resources and cooperative projects, with Research and Development (R&D) in the business world. Just over ten years ago, the Foundation’s programs geared towards Technological Innovation began to produce a revolution in the way scientific and technological research was financed in Brazil, as well as obtaining results of high impact in very competitive areas. Brazilian scientists, in partnership with national and transna- tional technology-based companies, developed original projects which resulted in inno- vations with a potential for competing with technologies produced in the great world centers. Some examples of this are synthetic diamond drill bits for use in dentistry, advanced devices for fiber optical communication, technology for the early and more accurate diagnosis of skin cancer, a new type of fibrocement to replace asbestos, or improvements in the control and planning strategies of the operation of oil refineries which resulted in tens of millions of dollars in benefits. FAPESP’s first initiative in the direct funding of innovation occurred at the end of 1994, when it decided to put into practice a program for research projects, which in addi- tion to supporting the training of researchers and the creation of knowledge, also sought its dissemination and application, facilitating the interactions for the transformation of knowledge into wealth. In tune with society’s wishes, FAPESP accepted the challenge of adding to its mission to promote scientific research, the commitment to creating opportunities to support eco- nomic development, financing research projects created and developed in partnership between academic institutions and private enterprise. The concern was to engage the aca- demic sector’s research offer with the demand from the business sector. The main novel-

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ty was the requirement for a partner business that demonstrated real interest in the trans- fer of technology which the project proposed to create. With risks and costs shared, this would also guarantee the possibility of overcoming prejudices in the relationship between the academic and business environments.

Backing businesses

Thus, in 1995, the first of the current twelve programs geared to Technological Innovation began to operate. Conceived in the Scientific Directorate and approved by the Foundation’s Governing Body, the Partnership for Technological Innovation Program (PITE) began to accept proposals that year. And, after ten years of activity, it now numbers 90 approved projects and an investment of over R$ 90 million, or US$ 37,5 million – 46 per cent of which contributed by partner businesses. The program is open to researchers from research institutions based in the State of São Paulo in partnership with businesses of whatever size regardless of whether they are headquartered in Brazil. The part of the pro- ject financed by FAPESP is developed in the academic research institution.

Brazil: according to the UN, an outstanding region for investment in technology

Index of Technological Achievement Leaders Potential leaders Dynamic followers Marginalized No data avaliable

Classification according to technological innovation Points 16 - maximum

4 - minimum

Translating Research into Business • 7

In addition to promoting partnerships between academic institutions and businesses, FAPESP perceived that there existed in São Paulo a scientific and technological base capa- ble of creating and developing small innovative businesses. Consequently, it set up the Technological Innovation in Small Businesses (PIPE), which supports scientific and tech- nological research projects undertaken in small businesses. Created in 1997, in its first year of activity PIPE received 82 proposals and 32 of them were awarded finance. Today, more than R$ 71 million, or around US$ 29,5 million, have already been invested in the 435 approved projects. Of these, 64 per cent are in the second phase or are actively seek- ing capital for the commercialization of their results in Brazil or abroad. PIPE is based on the Small Business Innovation Research program (SBIR), main- tained by the National Science Foundation (NSF) in the United States. The projects are developed in three phases, within the small business, they do not require the investment counterpart and they must lead to an innovation with commercial value. In phase 1, the viability of the proposal must be studied. In phase 2, a prototype of the proposed inno- vation is developed. In phase 3, aimed at the development of products, the Foundation may finance a small business through partnerships such as that made possible by the Support for Research in Businesses Program (Pappe), run by Finep which is an agency of ADO Ç SIRIO CAN

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the Ministry of Science and Technology. Partnership with the Brazilian Support Service for Micro and Small Businesses in São Paulo (Sebrae) is another means of support for the development of business plans. One of the assumptions is that micro and small businesses are important vectors of technological development, that is to say, they are capable of creating technology which could reach the production line or be licensed by larger businesses. The program also seeks to encourage undergraduate and post-graduate students to set up businesses, with a strat- egy of incorporating knowledge produced in the academic environment into a product, developing research aimed at innovation.

Expansions

The confirmation that investments of this nature do indeed bring significant socioe- conomic returns opened perspectives for the formation of groups of businesses from the same economic sector, in partnership with teaching and research institutions in the State of São Paulo, for the solution of shared technological problems. This perception led FAPE- SP to offer a third form of university-business cooperation: the Sectoral Consortiums for Technological Innovation or the ConSITec Program. Jointly responsible for the creation of a considerable number of innovations, FAPESP decided to organize the Program for the Support of Intellectual Property (PAPI), which operates within the ambit of the Nucleus for Patenting and Licensing of Technology (Nuplitec). This program assists the researcher in the protection of intellectual property arising from the results of the project and has already financed 114 patent requests since May 2000.

Programs

The affinity between projects and its vocation to produce original industrial products and processes led FAPESP in 2002, to classify as Technological Innovation some of its pro- grams with that characteristic. Today, in addition to PITE, PIPE, ConSITec and PAPI- Nuplitec, there are a further eight programs: FAPESP-Genome, with 17 projects and sub- projects of genetic analysis and sequencing; FAPESP-Biota, to inventory and characterize the biodiversity of the State of São Paulo, with consequent bioprospection for pharma- ceuticals; Centers for Research, Innovation and Dissemination (Cepid), which supports ten centers of excellence in scientific and technological research; Information Technology in the Development of Advanced Internet (Tidia), for the study of digital communications networks; Network for Structural Molecular Biology (Smolbnet), to elucidate structures of proteins associated with sequenced genes in the FAPESP-Genome program; Viral Genetic Diversity Network, to study genetic varieties of viruses of importance to public health; Integrated System for Hydrometeorology in the State of São Paulo (Sihesp), which involves studies on the hydric resources in the State of São Paulo; Public Policies, aimed at providing support for public administration; and Technology Parks, to promote the incor- poration of science and technology in the entrepreneurial sector.

Science,Technology and Development

FAPESP’s most recent program arose out of an initiative of the government of the State of São Paulo to promote and develop Technology Parks. The program centers on the exist- ing competitive base in the State for the production of academic research and the training of human resources, involving the four most important Brazilian poles for the production of technology, located in the capital and in the regions of São Carlos, Campinas, and São

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Four great technological poles

The cities of São Paulo, Campinas, São José dos Campos and São Carlos have universities, research centers of international caliber, availability of qualified personnel and high technology businesses LUIZ GRANZOTTO/PREFEITURA LUIZ Campinas O/PREFEITURA ÇÃ DIVULGA São Carlos JARBAS MOURA ROSA PMSJC EDUARDO CESAR EDUARDO São Paulo São José dos Campos

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José dos Campos. This is a strategic governmental program for the development of the State of São Paulo, operated by FAPESP through an agreement signed in November 2004 with the Secretariat for Science, Technology and Economic Development (SCTDE). The program brings together and complements initiatives from the local academic institutions for the development of the Technology Parks. SCTDE contributed R$ 2,5 million, more than US$ 1,04 million, for the development of business plans and the study of partnership alternatives with the private sector, and a further R$ 17 million (US$ 7,1 million) has already been designated for investment in infrastructure. Supervised by independent specialist consultants, this system of Technology Parks is intent on incorporating Research and Development in private enterprise, leading to the development of innovations in businesses, increasing their competitiveness and distribut- ing benefits to society. The initiative is sowing its seeds in fertile ground, given that a report published by the United Nations in 2001 showed the State of São Paulo to be one of the outstanding regions for investment in technology, in competitive comparison with other world centers. The United Nations Human Development Report for that year, included a ranking of the tech- nological development of 72 countries, classified on the basis of a Technology Achievement Index (TAI). This index evaluates processes of creation, use and dissemination of tech- nologies. Brazil held two of the 46 World Centers of Technological Innovation – one in São Paulo and the other in Campinas. Another document, published in September 2004 by the Economist Intelligence Unit (EIU), an economic analysis unit from the same group that publishes The Economist magazine, placed Brazil in sixth place out of countries where busi- nesses from all over the world intend to invest in Research and Development up till 2007.

In which of the following countries is your business planning to invest more in R&D in the next three years (excluding your domestic market)? (The ten most quoted out of 54) (% of replies)

1. China 39

2. United States 29

3. India 28

4. United Kingdom 24

5. Germany 19

6. Brazil 11

7. Japan 10

8 = France/Italy 9

10. Czech Republic 8

Source:The Economist Intelligence Unit

Translating Research into Business • SUMMARY 11

PARTNERSHIPS FOR TECHNOLOGICAL INNOVATION

PITE EDUARDO CESAR EDUARDO

Agrarian Sciences 8 Evaluation of the Production 1 Potential of Embryos in vitro Agronomic and Industrial of Cows with High Genetic Evaluation of Citrus Varieties, 35 Value and Acquired Infertility, 37 2 9 Development of a Program for Food Dispenser for Larvae and the Management of Elodea densa and Fish Farming of Pacu and Matrinxã,38 Egeria densa in the Jupiá Reservoir, 35 10 3 Alteration of the Quality Food and Agriculture Quality in of Eucalyptus Wood, 38 a Market Economy: Organic Production and the Certifying of Farm 11 Products for Obtaining a Green Seal, 35 FORESTS: Eucalyptus Genome Sequencing Project Consortium, 39 4 Study of the Technical Viability 12 of Microriveted Cans for the Development of Molecular Storage of Edible Vegetable Oil, 36 Markers based on ESTs of Sugar Cane for Selection of Economically 5 Important Characteristics, 39 Development of Technology Aimed at the Use of Derivatives of Yeast 13 in Human and Animal Foodstuffs, 36 Identification of Molecular Markers Attached to Genes Resistant to Race 1 6 of Oidium (Sphaerotheca fuliginea) Increase in the Biomass of the and to Papaya Ringspot Vírus,Watermelon Eucalyptus Tree by the Introduction of Strain, in Melon (Cucumis melo), 39 the CAB Gene via Genetic Modification, 37 14 7 Sequencing of Environmental Coloring as a Reproduction Bovine Expressed Assistant and Reducer of Cannibalism in Matrinxã,37 Sequence Tags (Best), 40

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Biological Sciences Health Sciences 15 28 Production of Botulinic Development of a Transference Serum,Toxins and Vaccines, 40 Mold – Zanetti Technique, 50 16 29 Project: Construction and Operation of a Pilot Development of Optimized Implants Plant for the Recovery of Gallium from Bayer Liquor, 41 for the Areas of Low Bone Density and Products for Bone Regeneration, 50 17 In vitro and in vivo Evaluation of Nineteen Exact and Earth Siences Molecules with High Anti-inflammatory Potential, 41 30 18 Implementation of a Telemedicine Purification and Description and Medical Practice Support Network of the Antigens of Pork Tapeworms Covering the Whole Brazilian Territory, 30 (Taenia crassiceps) for the Development of Diagnostic Reagents for Human Cysticerosis, 41 31 Development of Remote Management 19 System for Quality Control Programs in Analysis of the Life Cycle of Imaging Diagnosis Departments, 51 Packaging for the Brazilian Market, 42 32 20 Project and Implementation Control of Contamination by Filamentous of an Automatic Grammar Reviser Fungi, and Heat Resistant Actinomycetes in for the Portuguese Language, 51 Aseptically Processed Tomato Derivatives, 42 33 21 Pilot Training System: Development of a New Aircraft Cabin Simulator52 Class of Anti-Hypertensive, 43 34 22 Application of Plasma Torches Krahô Project: Study in Steel-making Processes, 52 of Medicinal Plants, 43 35 23 Development of High Power Adaptation for Veterinary Use Lasers with Emission in of the Type Rabies Antigen in the Spectral Region of 800 Adhered BHK Cells Used for Humans, 43 to 1000 nm, Based on Hetero Structures of GaAs/InGaAsP/InGaP,52 24 Development of Vaccine Against 36 Group A Beta Hemolytic Streptococcus, 48 High Performance Solver for Structured Optimization Problems, 53 25 Microencapsulation of Human Pancreatic 37 Islands and Tissue Engineering as New Inorganic and Hybrid Alternative Treatment for Diabetes Mellitus, 48 Phosphate-based Pigments, 53 26 38 Transcriptome Continuous Production of Fuel of Sugar Cane, 49 Alcohol Using Saccharomyces cerevisiae Supported by Chrysotile, 54 27 Development of System for 39 Control of Ant Colonies ReGra Project: New Challenges for in Urban Environments, 49 Automatic Grammar Revision, 54

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40 52 Development of a Differential GPS Optimization and Advanced Control System for Positioning and Guidance of the Cyclohexanol Reactor at Rhodia’s of Aircraft in Real Time, 55 Chemical Plant in Paulinia, 59 41 53 Application of Advanced Computational Prumo – Project of Mobile Units Fluid Dynamics for High Performance Aircraft, 55 for Technological Assistance for Micro and Small Businesses (MSBs), 60 42 Identification of Derivatives of Stability and 54 Control Of Aircraft via Non-Linear Filtering Development of a Polymerization and Stochastic Optimization: Algorithms and Process for the Production of Polymers Data Application from Test Flights, 55 with Low Residual Monomer Content, 60 Engineering 55 Development of Electric Steels, 60 43 Program for the Development and 56 Construction of Mechanical Heart Production of Compounds Based on Natural Valves and from Bovine Pericardium, 56 Fibers for Use in the Automobile Industry, 61 44 57 Optical Fiber Catheter for the Development of the Production of High Diagnosis of Atheromatosis Platelets Speed Steel Rolls for Hot Strip Rolling, 61 in the Cardiovascular System, 56 58 45 Study of the Process of Continuous Development of Technology for Two- and Casting of Thin Plates, 62 Three- Dimensional Aerodynamic Trials for High Performance Aircraft Project, 57 59 Development of a Test Methodology 46 for Alloys that Resist Carburetion and Panels of Cement from Clinker Catastrophic Carburetion, 62 Reinforced with Fiber Glass E (E-GRC), 57 60 47 Synthesis and Characterization of Development of Technology Advanced Carbonous Materials, 63 for the Manufacture of Fibro-cement Tiles without Asbestos, 57 61 Industrial Applications of Nitriding 48 Methods with Plasma Ovens and Ionic Development of Corrugated Implantation for the Treatment of Steels Cardboard Packaging Systems Used in Car Transmission Systems, 63 for Fruit and Vegetables, 58 62 49 Development of a New Automated System for Security Synthesis Process of Polypropylene Copies and the Recovery of with High Resistance to Melting, 63 Backup/Restore Files on Heterogeneous Platforms, 58 63 PRUMO – Projects of Mobile 50 Units for Technological Assistance System for the Visual and/or Sound for Micro and Small Businesses (MSBs) Location of Fixed or Moving Objects, 59 of the Surface Treatment Sector, 64 51 64 Development of Integrated Optimization Parallelization of the Adjustment of the Background of the Units of an Oil Refinery, 59 of Production in Management Networks Using PVM, 64

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65 74 Recycling of Aluminum: Development of Study of the Influence of the Characteristics Technological Innovations, 65 of Phosphated Layers in Stamping Operations with and without Lubricants, 69 66 Strategic Reorganization and Technological 75 Innovation in the Product Line, 65 Behavior of Aeronautical Materials and Structures 67 Subjected to Impact, 69 Evaluation of the Recycling of Industrial Residues Derived from the Synthesis of 76 Styrene and the Rolling of Metallic Aluminum, Prumo – Project of Mobile Units for Technological with a View to their Application in the Assistance for Micro and Small Businesses in Protection of the Covering of Civil Constructions, 66 the Shoemaking Sector of the State of São Paulo (Franca-Birigüi-Jaú), 70 68 Development of a Reactor 77 for Sterilizing Waste Water, 66 Prumo – Project of Mobile Units for Technological Assistance for Micro and Small Businesses 69 in the Industrial Sector of Plastics Transformation, 70 Geochronology Laboratory with High Resolution Ionic Microprobe: Support for 78 Development of High Technology Geoscientific Dedini Rapid Hydrolysis (DHR Process) – Projects in Oil Exploration, 67 Design, Implementation and Operation Unit Development Process (UDP), 71 70 Synthesis and Characterization of Copolymers of 79 Alphamethylstyrene-Styrene Aimed at its Application Development of System of Control in the Encapsulation of Silica Particles, 67 of Process of Crystallization in Suspension Through Monitoring of 71 Concentration and Distribution, 71 Properties of Mixed Systems Prepared from Mixtures of Carrageenans and Tensoactives, 67 80 Prumo – Project of Mobile Units 72 for Technological Assistance for Micro Prediction and Solubility and Small Businesses in the Industrial of Polar Polymers and Crystalline Sector of Rubber Transformation, 71 Solids in Solvent Mixtures, 68 Human Sciences 73 Prumo – Project of Mobile Units for 81 Technological Assistance for Micro and Primary Level Reading and Small Businesses in the Wooden Furniture Writing Project for Members of Making Sector in the State of São Paulo, 68 Staff at Cia. Nestlé de Alimentos, 72

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TECHNOLOGICAL INNOVATION IN SMALL BUSINESSES

PIPE EDUARDO CESAR EDUARDO • The project texts retain the objectives of the proposals as they were originally presented.

1th Bidding Instructions 8 Development of General Purpose, Low-cost, Controller 1 operated by a with the Capacity for Human Growth Hormone Production Remote Data Communication in Multipoint Networks, 77 using Recombinant DNA Technology, 75 9 2 20-Meter Range Laser Optimization of the Yields from Bacterial Distance Meter for Industrial Use, 78 Expression, and the Fermentation and Purification of Recombinant Human 10 Growth Hormone in order to Enable Daily Production Control at a its Production and Sale, 75 Chicken Slaughterhouse, 78 3 11 Use of Computer Learning Development of a 16xE1 Multiplexer/Optical and OCR Mathematical Modem with Technological Innovation, 78 Morphology in the Computer Stage, 75 12 4 Development of VDS Sheets (Vibration Improvement of the Vacuum Press Filter Damping Steel) for Absorbing Noise and Vibration, 79 for the Sugar and Alcohol Industry, 76 13 5 Production of Ultra-Pure Development of Refrigerators Manganese Carbonate, 79 Based on Thermo-acoustics Phenomenon, 76 14 6 Research and Development A Computer System for into Micro-controlled Systems for Analyzing Injuries to the Skin, 76 Monitoring the Milling of Components Using Acoustic Emission, 79 7 Project and Development 15 of Equipment for Neonatal Development and Assessment of Phototherapy Based on Pseudo-chelates in Bleaching Pulp Paste with Corrugated Optical Fiber, 77 H2O2 and in Inhibiting Equipment Corrosion, 80

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16 29 Advanced Materials for the Manufacture of Cast Manufacturing of Bipolar Separators Quartz Products, 85 for Ion Conducting Polymer Fuels Cells, 80 30 17 Research and Technological Development Development of Technology for Assessing into the in vitro Transfer of Embryos, and Environmental Risk in Places with their Sexing and Fertilization, 85 Contaminated Underground Soil and Aquifers, 80 31 18 Biological Markers of Occupational Automatic System for Exposure to Benzene, 86 Monitoring Vehicle Routes, 81 2th Bidding Instructions 19 Development of a System for Measuring 32 the Concentration of Pollutants in the Assisted Cutting of Atmosphere with Infrared Lasers (CO2 e CO) Digital Images and Videos, 86 using Photo-acoustic Spectroscopes, 81 33 20 Development of Systems for Equipment for Predicting Fungal R2/MF Signaling Using Diseases in Vegetables, 82 New Signal Processing Techniques, 87 21 34 Enscer – Computerized and Integrated Development of an Intra Surgical System for Teaching and Assessing Topograph (first prototype), 87 Learning and Neural Progress in Mentally Deficient Children, 82 35 Development of an Endoscope Video 22 Camera with an Optical Gradient, 87 Technological Development of Micro-environmental Systems for the Rearing, 36 Maintenance and Experimentation of Chemical Metrology Laboratory, 88 Small Animals in Breeding Units, 83 37 23 Evaluation of the Residual Spectrophotometric , 83 Water Treatment System from Cassava Processing, 88 24 Instrumental Evaluation of the Quality 38 of Pork and its Uses in the Meat Industry, 83 Stereotrips II: Stereoscopic Computer Graphic Techniques 25 and Synchronized Audio-Video Electrocardiograph Linked for Multimedia Applications, 88 to a PC with an End Cost of between R$ 500 and R$ 1,000, 84 39 DNA Automatic Sequencing in 26 Molecular Diagnostics: Analysis of Bragg Grid Characterizers the Efficiency, Reproducibility in Optical Fiber, 84 and Costs of Different Methods, 89 27 40 Diamond Sanders, 84 Technological Innovation for the Financial World, 89 28 Development of the 41 Technology of Molding of Metropolitan Wireless Ceramic Items by Injection, 85 Network – Wireless MAN, 90

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42 55 Low Noise Amplifier with Frequency Optimization and Classification Project Converter in KU Band (LNB – Low Noise on Biodegradable Polyurethane Foam, 95 Block) for Use with Parabolic Reflectors, 90 56 43 Development of Coatings Intended for Inertial Sensors Integrated the Use of Organic Corrosion Inhibitors Platform/Global Positioning and to a Reduction in the Use of Solvents, 96 System (GPS), 90 57 44 Technological Innovation in the Recycling Development of Plasma of Plastic Bottles from Gas Stations, 96 Processes Applied to Metallurgy, 91 58 45 Development of a Development of a Self-Propelled Sprayer/Duster Plasma Sterilizer, 91 for Treatment in Citrus Orchards, 96 46 59 Development of Modular Estocastic Analysis of the Temporal Dynamics and Configurable Equipment for of Cardiac Arrhythmias through Intermittent the Capture and Digital Recording of an Electrocardiogram, Processing of Biological Signals, 92 for Very Long Time Periods, 97 47 60 Development of Semiconductor Laser Applications of Cooperative and Equipment for Medical Applications, 92 Communication Work for Educational Institutions, 97 48 61 Transportable Odontological Module, 92 Development of Systems for Localized and Rationalized Application of the Technology 49 of Herbicide Application for Railroads, 98 Development of a Generic Planning Solution of Automatic Processing for 62 Parametric Parts, 93 Technological Development of Special Compact Autonomous 50 Air-Conditioning for Use in Application of Conductor Microenvironmental Cabinets for Polymers as Gas Sensors, 93 Animal Testing Laboratories, 98 51 63 Development of Devices Obtaining (gamma) MnO2 for in CVD-diamond for Short use in Batteries from Different Term Applications, 94 Manganese Compounds, 99 52 64 Manufacture of Credit Cards, Applications of Lasers Open and Closed Plastic Cards, 94 in Materials Processing, 99 3th Bidding Instructions 4th Bidding Instructions 53 65 Technological Modernization of SISOFT 14001 – Software for Optical Amplifiers by Erbium Doped Fiber, 94 Supporting the Preparation of an Environmental Management System, 100 54 Studies of Acidification of Raffinate in Kuhni 66 column, to Increase the Yield in the Development of a High Phosphoric Acid Purification Process, 95 Performance Ozone Generator, 100

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67 80 Improvement in the Quality of Precious Stones Development of Advanced Materials through Microbiological Purification and for Lithium-Ion Battery Electrodes, 106 Induction of Color through Ionizing Radiation, 101 5th Bidding Instructions 68 Experimental Bench 81 for Ratifying Software and Pre-Distortion Linearizer Hardware for Intelligent Batteries, 101 for High Power Amplifiers for Land-based Satellite Stations, 106 69 Anodic Oxidation with Aluminum 82 Plasma in an Aqueous Medium, 101 Optical Precision Microscope with Synthetic Granite Base, 107 70 System for MonitoringUrban 83 Public Transport Vehicle Fleets, 102 Development of a User Terminal for Transmitting and Receiving 71 Voice and Data by Satellite, 107 Program Decompressing System for Risc Processor, 102 84 Ink Jet Space-Time Recorder, 108 72 Development of an STM-1 Multiplexer 85 for Optical Access Networks, 103 Development of Natural Christmas Trees for Brazil, 108 73 Call IP – Telephone Switching System 86 for Call Centers Using Voice Over IP,103 Low-Cost Solar Heater, 108 74 87 Ceramix – Computer System Hybrid, Broadband, High-Gain for the Formulation and Amplifier Module, Using Hybrid Reformulation of Ceramic Paste, 103 Copper Plating Technology in an Alumina Substratum, 109 75 Development of a 88 Bacterial-Toxoid Vaccine to Optimization of the Process Prevent the Poor Egg-Shell Quality of Vulcanization of Retainers Syndrome in Breeder Birds through Microwaves and Commercial Laying Hens, 104 and Compound Material Molds, 109 76 89 The Use of Molecular Techniques in Automatic Reconfigurable Farming: Improvement of the Genealogical System for Testing Recording of Cattle and Horses, 104 Electronic Modules, 109 77 90 Development of a Reworking Welded Tubular Low-cost, Geo-referenced, Aeronautical Structures – Steel ABNT Electronic Penetrometer, 105 Brazilian Association of Technical Rules) 4130, 110 78 Study of the Process 91 of Freezing Bread, 105 Solar Collector Manufacturing Process, 110 79 92 Optical System for the Automatic Development of a Tool for Positioning of Screens (Sopat), 106 Optimizing Structures, 111

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93 105 Pulsing Current and Squared Wavelength Development of a Micro Rectifier for Anodizing Aluminum, 111 Controlled Deformation Gauge with a Communication Interface, 116 94 Improvement of the Surface Properties 106 of Industrial Components through Electro-Mechanical Packaging Three-dimensional Ionics Implementation, 112 of Micro Pressure Sensors, 116 95 107 Generation of Digital Elevation Use of Clean Technology in the Models using Radar Measurement with National Production of Active Principles Images from the Radarsat-1 Satellite, 112 with Pharmacological Activity, 117 96 108 Development of New Kits System for the Management of “Dusting” Destined for the Diagnosis of in Agriculture with the Technology of Intestinal Parasites in Feces Samples, 112 Automatic Acquisition of Field Data, 117 97 109 Universal Interface System Portable Inductive System for Distance Control, 113 for the Imaging of Steel Bars in Concrete Structures, 118 6th Bidding Instructions 110 98 Recognition of System of Detection and Localized Digital Fingerprint, 118 Application of Herbicides on Sugarcane, 113 111 99 System of Tracking, Control Genetic-Biochemical Properties of Four and Remote Immobilization, 118 Strains of Nile Tilapia (Oreochromis niloticus), Aimed at their Genetic Improvement, 114 112 Study for the Development of 100 Distance and Level Gauges Using Implantation of the PCR Technique for the Microwaves (radar) and Laser (optical), 119 Detection of Genetically Modified Foodstuffs, 114 113 101 Reticulation of Coating, Development of Seedlings Quality Control Based on EPDM using in Laboratories Allied to Biotechnology, 115 Ultraviolet Radiation (UV), 119 102 114 Oral Implant Device for Front Positions with Gearing Pump of Variable Flow, 119 Threaded Fixing in the Second Cortical, Articulated, with Titanium Plasma Spray in the Active Region and 115 Hydroxiapatite in the Paste, Head with an Esthetically System for the Low Cost Adequate Diameter and with an Anti-Rotational and Fast Drilling of Deep Tubular and Screwed Prosthesis Fixation System, 115 Wells in Hard Rock, for Obtaining Underground Water, 120 103 Development of a System 116 of Ionizing Radiation Monitors, 115 Optical Components in Injected Plastic with Non-Spherical Surfaces, 120 104 General Use Computer Program and Software 117 for the Modeling of Drainage and for Production of Pigments the Transport of Contaminants by Monascus sp in in Natural and Artificial Waterways, 116 Semi-Solid Fermentation, 121

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118 131 A Computerized Systemfor the Development of a Bacterial-Toxoid Vaccine Analysis of Human Chromosomes, 121 (VT) and the Production of Immunized Yolks for the Prevention of Post Weaning Diarrhea 119 and Edema Illness in Pigs, 130 Geophone – Integrated System for Obtaining Geo-Referenced 132 Information for Emergency Services, 121 Development of a Decision Support System in the 120 Management of Reservoirs, 130 Flexible Manufacturing of Chocolates and Innovation 133 in the Basic Line of Products, 122 Projects for Odontological Implants Associated with Hydroxiapatite and 121 Titanium Particle Coated Surfaces, 131 Money Exchange System and Foreign Trade, 122 134 Development of a System to Increase 7th Bidding Instructions Afocal Apochromatic Zoom for Ophthalmologic Surgical Microscope, 131 122 CD-ROM for City Planning, 123 135 Identification of Aromatic 123 Compounds in Brazilian SETAS – Electronic Fruit for the Creation of New Safety Triangle System, 123 Aromas for the Food Industry, 132 124 136 Development of Optical Spectrophotometer Based on Attenuator Technology, 128 a Pulsating Xenon Lamp and Linear Image Sensor, 132 125 Design and Industrialization 137 of Furniture, 128 Development of Equipment for the Determination of Ocular Aberrations Using Wave-Front Measurements 126 by way of the Harmann-Shack Technique, 132 Ultrapurification of Natural Products through Molecular Distillation, 128 138 Micro-Computerized System for 127 the Gauging of Functional Parameters Development of a of Radio Diagnostic Equipment, 133 Connectable Crusher Cart linked to a Caterpillar 930 Tractor 139 and its Application in the Production Pumping System for the Extraction of of Organic Material Compost, 129 Petroleum Using the Linear Tubular Motor, 133 128 140 Post Fruit Harvesting Protection, 129 System of Video-Auditing for the Control of Vehicles in Car Parking Lots Through Images, 133 129 Study of the Technical Viability 141 for the Installation of a Bromeliad Research and Development of Bio Factory in the Ribeira River Valley, 129 a Low Cost Digital Network for the Automation of Buildings, 134 130 Survey of the Technical Parameters for 142 Managing a Sustainable Income Development and Classification of from Species with Medicinal Potential, PET/HDPE Polymer Blends, Employing Native to the Atlantic Rain Forest, 130 Post-Consumer Polymers, 134

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143 154 Development of a Low Cost Recording system for Measurements Recycled PET Compound for the of Electrical Energy Transmission Manufacture of Fireproof Sockets, 135 of Data to the Concentrator via Communication “Carrier”, 140 144 Software for the 155 Development of Worn Parts, 135 Myconate Project 8th Bidding Instructions 156 Automatic Vending Machine 145 for the Sale of Natural Juices, 140 Training System for Chemical and Petrochemical 157 Processes (STOP QP), 135 A Computing Tool for the Programming 146 of Urban Bus Routes, 141 Synthesis of Molecular Sieves from Carbon Precursors, 136 158 Development of Fuel Cells 147 Integrated with Hardware Analysis of Fatigue in and Software for Monitoring, Semi-articulated Trucks, 136 Diagnostics, Control and Peripherals , 141 148 159 Development of a Chemical Industrial Use Electron Accelerator , 142 Mechanism for the Controlled Release of Bioactive Ingredients for the 160 Microbiological Treatment of the Development of a Polymeric System Internal Air in Climatized Atmospheres, 137 for the Transmission of Light, 142 149 161 Obtaining Zinc Coating and Zinc Fluorescence Spectrophotometer Alloys by Electro-deposition Using with a Double Monochromatic System Modulated Current, its Passivation via of Continuous Sweeping, Based Process Devoid of CrVI Followed by on a Xenon Pulsating Lamp, 143 Application of Water-based Resin, 137 162 150 System of Automatic Measurement of Design, Simulation and the Cornea’s Curvature Rays with a Slit Lamp – Development of Static Automatic Keratometer with Slit Lamp, 143 Mixers for Liquids, 138 163 151 Development of Photo Conductive Cones Obtaining Chelated Pharmaceutical for the Obturation of Canals with and Food Grade Amino Photopolymerizable Obturating Material, 144 acids from Natural Sources, 138 164 152 GPS Receiver, 144 Production and Commercialization of Equipment for the 165 Electrochemical Removal of The Establishment of a Metrological Standard for Metallic Ions from Aqueous Effluents, 139 an Audiometric System with Parameters for the Respective Functions of Calibration and Reliability, 145 153 Design and Development of Flexible 166 Video-Endoscopic Equipment Using Development of a Tar Based Resin Fiber Optics Consistent with Use in with Enhanced Properties for Gastrointestinal Diagnosis and Treatment, 139 Use in the Graphics Industry, 145

• Translating Research into Business 22

167 179 The Production of Amino Acid Chelates iGate – Gateway with Direct from Hydrolyzed Proteid of Saccharomyces Connection to the Internet, 150 cerevisiae to be Used as Mineral Food Supplements of High Bio-Availability, 146 180 Application of Parallel Computing 168 Techniques to the Solution of Problems LF line Project, 146 in the Logistical Optimization, 151 169 181 Thermo-chemical and Plasma Development of a Low Cost System Treatment of Carbon Steel Reels, 146 for the Generation of a Differential Correction Signal, in Real Time, for GPS, 151 170 Finished Polyether Silil-based Adhesives and 182 Sealants for use in Industry and Civil Engineering, 147 Industrialization of Biodegradable Starch Films, 152 9th Bidding Instructions 183 171 Project for Monitoring Development of Expander Agent Based on Equipment for Gastroesophagal Aluminum Slag for the Production of Autoclaved Reflux Disease (DRGE) with or Molded Cellular Concretes in loco, 147 Innovative Use in Biliar Paths, 152 172 184 Instant Whole Bean: Study of the Preparation of Critical Conditions in the Process, 148 Magnesium Hydroxide as Antiflame in Polymers, 152 173 Safety Culture in Activities 185 Involving Ionizing Radiation, 148 Editing and Publication System for the WWW, 153 174 Malleable Pleated Valve with 186 Self-Adjustable Flow Mechanism Diagnostic Kit for Potentially for Pleural or Mediastinal Deteriorating Micro-organisms, 153 Drainage Collection System, 148 187 175 Preparing Future Entrepreneurs, 154 Production and Characterization of Environmentally Degradable Polymers (EDP) 188 From Renewable Sources: Sugar Cane, 149 Recovery of Lead Metal by an Electrohydrometallurgical Process, 154 176 Production of Pre-alloyed Metal 189 Powders by Atomization for Methodology of Online Application in the Manufacture of Teaching Applied Tablets for Addition of Alloying to Courses Geared Elements in Aluminum Metal Baths, 149 to Information Technology, 154 177 190 Interphone Communication Development of High System via Electricity Network, 150 Accuracy Current Transducers with Microprocessed 178 Re-excitement Mesh, 155 Control Network of Devices withDistributed Intelligence with Voice and Data Communications Interfaces 191 with Public Exchange Telephone Lines, Applied to Photovoltaic generators Residential, Commercial, Industrial Automation, 150 for Aerospace Applications, 155

Translating Research into Business • 23

10th Bidding Instructions 204 Evaluation and Optimization of the 192 Metallurgical Properties of Aluminum Applied Molecular Biology to Billets for Extrusion Produced the Rational Management of Ostriches, 156 from Recycling of Scrap Metal, 160 193 205 Development of the Technology Study of the Means of Controlling the for the Metallization of Optical Flowering Time of Oncidium flexuosum sims. Fibers by Chemical Process, 156 and Selection of Plants for the Reconstitution of Uniform Populations, 161 194 Mass Breeding and Commercialization 206 of Trichogramma spp and Cotgesia flavipes Production of Purified Plasmidial for the Control of Agricultural Pests, 156 DNA and Recombinant Proteins, on a Large Scale, for use in 195 Vaccines and Diagnostics, 161 Genetic and Zootechnical Evaluation of two Varieties of NileTilapia 207 (O. niloticus var. Red-Stirling and Visual Environment for O. niloticus var. chilatrada) for the the Development of Parallel Establishment of Program Real-Time Programs (Visual-RT), 162 for the Mass Production of a Hybrid of Red Tilapia, 157 208 Development of Computational 196 Tools for the Teaching and Advanced System for the Production Learning of CNC Usage Processes, 162 of Electricity with High Efficiency, Low Cost and Non Pollutant, 157 209 Development of Compounds 197 from Ceramic Waste as Management of Road Parcel Replacement for Granite, and Freight Services via Internet, 158 Wood, and other Quality Facings, 163 198 210 Electronic Anticorrosive Development of an Operational OX-FREE Protection, 158 Prototype for an Alternative Rotating Engine Known as Tetracycle, 163 199 Stoq: A Flexible System for 211 the Management of Development of Integrated Commercial Companies, 159 Management System for Ostrich Breeding ventures, 164 200 Interactive Experiments for Scientific 212 and Technological Education, 159 Manufacture of Self-reducing Manganese Pellets, 164 201 Development of Processes 213 for Syntheses of Desferrioxamine, 159 Production and Commercialization of Equipment for the Electro-Chemical 202 Treatment of Watery Industrial Effluents Complete Encapsulation Containing Organic Pollutants, 165 of Discardable Blood Pressure Transducers, 160 214 Development of Instrument for 203 Measuring Thermic Diffusivity Production of Porous Parts of Materials by the in High Performance Alloys, 160 Energy Pulse Method, 165

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215 228 Robotized System for HIC TV – Facilitator for Interactive Inspection of Tubing, 166 Shopping via Television and Radio, 171 11th Bidding Instructions 229 Integrated Project for Production 216 of Buildings – A New Methodology Development of High in Project Development, 172 Performance Adhesive For Use in Urban Traps, 166 230 Production of Concentrated, 217 Sterile, Liquid Culture Medium, for Optimization of Performance Cultivation of Leptospire Strains, 172 of Heat-reflecting Curtain, Aiming for Reduction of Energy 231 Consumed in Thermal Conditioning, 166 Improvement and Expansion of Software Platform for 218 National and International Io – Intelligent Sensor for Applications Dental Health Market, 173 in the Electrical Sector, 167 232 219 Optimization of the Production Fiber Optical Silica Amplifiers and Formulation of Doped with Erbium, 167 Biocontroller of Phytopathogens, 173 220 12th Bidding Instructions Development of an ELISA Kit for the Detection of Aflatoxine B1, Aimed at the 233 Control of Grains, Foods and Animal Foods, 168 SIGE – Integrated System for the Strategic Management of Business, 173 221 Graphical Model of the Dependence 234 between the Rules of Business and the Optical Fiber Sensors Physical/Financial Impact on Maintenance, 168 for the Detection of Chloride in Concrete Structures, 174 222 Parallel Processing 235 on the Internet or in Development of New Technologies Corporate Networks, 169 for the Multiplication of Bananas in High Volume Bioreactors, 174 223 Recycling of 236 Reticulated Polymers, 169 PABX over Local Network, 175 224 237 Development of Standardized Materials for Model for Corporate Portal the Manufacture of Herbal Remedies and in the Brazilian Banking Sector, 175 Vehicles appropriate for their Applications, 169 238 225 Production of Bio-Oil Use of Mobile Internet as via Fast Pyrolisis of a Tool for Distance Learning, 170 Agricultural Waste for Use as Fuel and Materials, 175 226 Clothes Press, 170 239 Establishment of New 227 Space for Agricultural Software for the Study Commercialization with Virtual of Hazard and Operability, 171 Reverse Auction – AGRO VIRTUAL, 176

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240 253 Development of Machine for the Fusion Biocompatible and Traction of Fibers for the Manufacture Metal Implants, 181 of Passive Optical Components, 176 13th Bidding Instructions 241 Development of Instrumentation 254 for Optical Fibers, 176 Research on Fuel Purifier Device, 181 242 Universal Wake-up System, 177 255 Network Quality Management 243 System – HORUS, 182 Development of Multi-user Gas Chromatograph, 177 256 Computational System for Reduction 244 of Losses in EnergyDistribution Development of Integrated System for Networks with Virtual Reality Interface, 182 the Production of High Quality Strawberry Seedlings in Protected Cultivation 257 and Sterile Substrate, 178 Development of a National 5Kw Aerogenerator, 183 245 System for Satellite Earth 258 Stations of Natural Resources, 178 Integrated Computational Platform for Teaching, Research and Development 246 of Telecommunications and Wind-up Free-fall Simulator, 178 Electronic Instrumentation, 183 247 259 Development of Equipment for the Wireless Optical Electro-chemical Recovery of Gold from the Communications System, 183 Watery Effluent of the Bijouterie Industry, 179 260 248 Development of New Development of Continuous Infrared Movement Detection Process for Incorporation of Vegetable Sensors for Domestic and Fiber in Thermoplastic Matrixes, 179 Business Security Applications, 184 249 261 Development of Equipment Band S Transmitter to for the Electrochemical Integrate Doppler Treatment Hospital Sewage, 180 Meteorological Radar System, 184 250 262 Multi-Satellite Modular FIEEL – Hardware Band S Receiver to Integrate Doppler for Control of a System of Uninterrupted Meteorological Radar System, 185 Supply of Electrical Energy, 180 263 251 Administration and Integration of New Support System for Decisions Information for Decision Taking on on Prices, Quotations and Costs Enterprise Resources in Small and for Small and Medium Enterprises, 180 Medium Businesses, Using Automated Management Tool, Providing 252 Diagnostics and Administrative Production of a Porous Body by and Operational Agility, 185 Means of Agglomeration of Fines of Active Carbon, to be Used as Filter 264 and Absorbed in Water Treatment, 181 Development of Thermoluminescent Dosimeters, 186

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265 278 Radio-controlled Agricultural Model Plane, 186 Antibacterial Counter Flow Air Purifier and Humidifier for Domestic, Pneumological 266 Clinics and other purposes, 191 Band S Antenna Set to Integrate in Doppler Meteorological Radar System, 186 279 Optimization of the Process of Organic Film 267 Formation by Cataforetic Deposition, Aiming Development of Bio-insecticide for Energy Savings, Environmental Protection Formulations Based on the Entomopathogenic and Adaptation of the Process Fungus Metarhizium anisopliae, 187 to National Climatic Conditions, 191 268 280 Biomaterials Based on Phosphates of Calcium Restoration of Value to Polyethylene/ Collagen for Reconstitution of Bone Tissue, 187 Aluminum Waste From Cardboard Packaging of Long 269 Life type, Post-consumption, 192 Computational Analysis of Genetic Paternity Test, 188 281 Development of the First 270 Brazilian Analyzer for Combustion Development of Foams Based Gases and Environmental Emissions, 192 on Starch and Their Application As Eco-sustainable Packaging, 188 282 Use of Titanium Powders 271 Obtained by the HDH Route, 192 Establishment of Unit for Recovery of Foundry Sand Contaminated 283 by Phenolic Resin by Heat Process, 188 Management of Companies Based on Projects via Workflow, 193 272 Project for Frequency Filters 284 Using SAW Technology for Application Research and Development of a Process in Cell Phone Repeaters, 189 for the Synthesis of Polypropylene with High Melt Resistance (HMS-PP) in Presence 273 of Multifunctional Liquid Polymers, 193 Development of Protective Polymeric Electrically Highly Conductive Films 285 for Application on Electrochemical Development of Inorganic Energy Generating Devices and Manufacture Low Toxicity Biocides, 198 of an Automatic Applicator, 189 286 274 Electromechanical Packaging of Fiber Optic Sensor for Environmentally Isolated Piezoresistant the Petroleum Industry, 189 Pressure Sensors Used in Industrial Pressure Transducer and Transmitters, 198 275 Development and Nationalization of the 287 Technology for the Manufacture of Clonazepam, 190 System for Generating Numerical Terrain Models Based on 276 Polarimetric Images from Band P Radar, 198 Spectroscope for Teaching, 190 288 14th Bidding Instructions Microencapsulation of Pigments for Application in Special Paints, 199 277 Development of Haploid-Inducing 289 Populations for Commercialization Training System of Double-Haploid Strains of Maize, 190 in the Area of Security, 199

Translating Research into Business • 27

290 302 Development of Equipment and Method Modeling and Development for the Dehydration of Fruit and Vegetables, 199 of a System for Integrated and Efficient Management 291 of Electricity Sector, 204 Cellular Module 2.5/3G for Machines, 200 303 Production of Colored Gold Alloys 292 by High Energy Milling, 204 Development of Optimization Solvers for Commercial Applications, 200 304 Development of Atomic Absorption 293 Spectrometer with Electrothermic Production of Linalool Atomization Using Tungsten based on Essential Oil of Basil – Filament Based in Pulsed Xenon a Sustainable Ecological Lamp and Linear Image Sensor, 205 Alternative to Replace Linalool from the Bendy Tree, an 305 Amazonian Threatened Species, 201 T-Learning – Learning Based on Interactive Digital TV, 205 294 Development of Technology of Production 306 and Improvement to Mechanical Production of Stainless Steel Properties of High Silicate Cast Iron, 201 Powder by Water Atomization, 206 295 307 Production of MnZn Ferrites with High Software Dental Software for Color Permeability and Low Magnetic Mapping and Selection of Restorative Loss by Co-precipitation Method, 201 Materials Aided by Computer – Phase 1: Determination of Colorimetric 296 Variation Curve of Resin Compounds, 206 Optimizer for Insertion of Adverts in Printed Media 308 Using Mean-Variance Model, 202 Hotel Environmental Adaptation Project – Diagnosis, Adaptation 15th Bidding Instructions and Environmental Innovation in Hotelier Sector, 206 297 Optical Reflectometer 309 (Not in Time-Domain), 202 Monitor: an Environmental, Socioeconomic, Operational and Production Monitoring System, 207 298 Development and Optimization 16th Bidding Instructions of a Process for the Electrosynthesis of Hydrogen Peroxide, 202 310 An Approach to Gradual Migration 299 from Legacy Applications, 207 Evaluation of Methodology and Techniques for the Industrial Production of Entomopathogenic 311 nematodes and Study of Market for SGEP – System for the Strategic Commercialization of these Agents, 203 Management of Projects; Computerized System for the Tracking and 300 Management of Projects, Development of a Controller Geared Towards Decision Makers, 208 for Application of Liquid Fertilizers, 203 312 301 Technological Development Development of Modular Software Platform for Precision Irrigation for the Analysis of Genic Expression, 204 of Perennial Crops, 208

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313 326 Development of a Computational Development and Manufacture Tool for the Design and Analysis of Mono and Bi-Propellant Injectors of Networks of Optical Packets, 209 for Low Thrust Thrusters Produced Through the Process of Solid State 314 Diffusion Soldering, 213 Development and Characterization of Blends of Ethylene Polyterephtalate 327 Recycled/Polycarbonate (PETr/PC), 209 Development of a Monitoring System for Multisensors, 214 315 Integrated Robotic System 328 for the Areas of Education, Development of Research and Entertainment, 209 Gravimetric Titrator, 214 316 329 Construction of a Metals Nitriding Plant Development and Qualification of Using a New Technology of Pulsed Plasma, 210 5N Mono-Propellant Satellite Thruster, 215 317 330 High Precision Intelligent Piezoresistant Development of Anti-evaporation Pressure Transmitters for Aggressive and Mixture for the Conservation of Fresh Water, 215 Non-Aggressive Environments, 210 331 318 Development of a process Development of Alumina-Based for Recovery and Recycling Cutting Tools, 210 of Rhodium from Waste Metal in the Semijewels Industry, 216 319 Project Workshop Kit, 211 332 Development of New 320 Functionalities for Development of Toplmplant Equipment, 216 PET-recycled/ABS Blend, 211 333 321 Classifier/Selector Improvement to the Quality of Machine for Oranges Using Recognition and Availability Computational Vision, 216 (SpeedCluster) of Griaule’s AFIS, 212 334 322 Security Logistcs Design and Construction of Self-Service System Using GPS, 217 Intelligent Kiosk for Demonstration, Adaptation and Commercialization 335 of Spectacles On-line, 212 Development of Dental Porcelains for the Making 323 of Dental Prosthetics, 217 IrisVision – The Eyes of Your Business, 212 336 324 Development of Complementary Development of a Process to Hot Vulcanize Organic Foods for Children, 217 Ten Tires Simultaneously, Research into the Heating Curve Parameters During 337 the Vulcanization Process for Retreaded Optical Service Channel, 218 Tires, with Automation of the Machine, 213 338 325 Optical Cross-Connect Ultra-Sound Tartar Remover with Liquid Crystal Based for Use in Dentistry, 213 Switching Matrixes, 218

Translating Research into Business • 29

339 352 Development of Material in the Form Production of Polyclonal Antibodies, 224 of Filament of the ABS Type for Use in FDM Rapid Prototyping Machines, 219 353 Generator of Systems for 340 Business Processes Based on BPM Identification System (Business Process Management), 224 for Polymorphisms, 219 354 341 Concentrator of Fixed and Mobile Method for Increasing ProductivityBased on the Telephone Services – CFM, 224 Fixation of the G2 Allele in the Promoting Region of the Growth Hormone Gene in Slaughter Cattle, 219 355 Development of Kits for Immunodiagnosis 17th Bidding Instructions of Canine Monocytic Ehrlichiosis, Using the Techniques of Indirect Immunofluorescence 342 (RIFI) and Indirect Immunoenzymatic Development of Automatic Electrolytic Tests (Dot-ELISA and ELISA-test), 225 Extractors for Heavy Metals in Effluents, 220 356 343 System for Measuring Project for the Development of an Real Time for Swimmers, 225 Experimental On-board Module on a Low Orbit Orbital Platform – “Sara” Project, 220 357 Development of a Low Cost System for the Supply 344 and Presentationin Various Media – Network, Manufacture of Rectangular Dental Thread, 221 Internet, Palm, PDA, Cell Phone, etc. – of the Strategic and/or Performance Indicators of an Organization 345 to its Executives and/or Owners of Processes, 226 Appropriate Disposal of Fluorescent Lamps which Contain Mercury, 221 358 Processor For the 346 Detection of Oil Spills, 226 Process for Multiple Operations of Sterilization, Homogenization, Inoculation and Packaging, 359 Aimed at the Production of Inoculants for the Process for the Obtaining, Composition Cultivation of Edible and Medicinal Mushrooms, 221 and Use of a System of Recombinant Hormones for Superovulation in Vertebrates, 226 347 Development of Optimized and Economically 360 Viable Process for the Production of Biosilicate Development of Dental Ceramics for Treatment of Dentinary Hypersensibility, 222 Based on Alumina e Zirconia, 227 348 361 Standardization and Validation of an Single Dose Vaccine Against Bovine Tick, 227 Elisa Kit for the Quantification of Chloraphenicol in Products of Animal Origin, 222 362 Generation of Graphical Interfaces for Parallel 349 Real Time Applications Based on Source Code, 227 Innovation in the Production Process of Composts for Special Edible Mushrooms, 223 363 Mini-Washing Machine, 228 350 Middleware for High Performance 364 Electronic Games on Network, 223 Provision of Dental Accessory, 228 351 365 Development of Continuous Production Optimization of Production Process for Large System for Torrefied Briquettes, 223 Scale Gain in the Micropropagation of Plants, 229

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366 378 Development of High Performance Sinterized Vitroceramics Laminated Armor Materials Composed for Ceramic Claddings, 234 of Alumina Ceramic and Fiber Fabric for Personal and Vehicular Ballistic 379 Protection to NIJ Ballistic Levels III and IV, 229 Synthesis and Production of Poly (L-lactic acid-co-D,L-lactic acid) 367 Implant Materials, 234 Study of the Technical Viability of the Use in Yoghurt of Natural Beetroot Coloring Obtained by Alcoholic 380 Precipitation (a New Methodology of Production), 229 Econometric Modeling Project for the Broadening of Knowledge of the Brazilian 368 Geoinformation Market, 234 Software for the Strategic Management of Knowledge, 230 381 GP-101, 235 18th Bidding Instructions 382 369 Development of a Telephone Machine for Polishing Terminal with Compensation Fiber Optic Connectors, 230 for Hearing Deficiencies, 235 370 383 Integrated Telemetric and Telecommand Development of a New System Solution Based on Wireless Technology of Multichannel Acquisition for for Refinement to Urban Services, 231 Pulmonary Monitor Based on Electrical Impedance Tomography, 235 371 Development of an Identification System 384 for the Rice Finch (Oryzoborus anglensis) Recycling of Plastic Bottles Using DNA Microsatellites, 231 at Gas Stations and the Like, 236 372 385 Planning Tool for Broadband Pharmacology,Toxicology Data Transmission Systems Via and Chemistry of the Oil the Electricity Extracted from Fatty Bodies Network Infrastructure, 231 of the Rana catesbeiana (Shaw), 236 373 386 Vitroceramics for Use in Applied Oceanic Electric Oven Plates, 232 Monitoring System, 236 374 387 Manufacture of Hospital Development of a piece of Washing Machines and Software for Pairing and Integration Consultancy to Hospital Laundries, 232 of Personal and Health Information, Using Record Linkage 375 Method and HL-7 Standardization, 237 Therapeutic Vaccine for Equine Melanoma, 232 388 Development of a Support System 376 for the Integrated Management Re-engineering of Large Scale Legacy of Pay-as-you-Fish businesses Systems Based on Frameworks, Distributed in the Central Region of the Components and Design Standards, 233 State of São Paulo – Fishing Project, 237 377 389 Microcamera Attached Precision System for the Localized to Frontal Surgical Illuminator, 233 Variable Rate Limestone Application, 238

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390 402 Development of a Methodology Development of Heat Pumps for Applicable for the Production of Residential and Industrial Applications, 242 Cationic Latex from Natural Rubber on a Commercial Scale, 238 403 SuperVision: Support System 391 for Railway Logistics and Operation, 243 Integrated System for the Obtaining of Georeferenced Information for the 404 Dynamic Control of Water Quality, 238 Quantitative Genetic Evaluation of Ostriches (Struthio camelus) in the State of São Paulo, 243 392 Novogesso, 239 405 Innovations in pH and 393 Conductivity Meters, 243 Development of High Capacity Oxygen Generating Equipment, 239 406 Hydropneumatic Linear 394 Position Controller, 244 Production of Intervariety Hybrids and Segregating Populations of Gerbera jamesonil , with Help from 407 Molecular Biology Techniques, Aiming to Produce On-Line Sales Tool, 244 New Commercial Cultivars, 239 19th Bidding Instructions 395 Development of Oxygen 408 Generating Equipment, 240 Development of Humidifier for Fuel Cells, 245 396 Conception and Development 409 of Prototype User Adaptable Interface Production of Silica-Aluminous for Building Automation Systems, 240 Fire Bricks with Chamotte Produced at Low Temperature, 245 397 Tracking, Monitoring and Debugging 410 Tools for the VisualRT Development Development of an Electronic Ear Visual Environment, 240 Tag for Cattle Identification, 245 398 411 Development of National Technology: Research and Development Production of Integrated Devices for of Microprocessed, Portable, and Low the Quality Control of Images Cost Videolaparoscopy Equipment, in Radiodiagnostics Equipment, 241 with Functions for Monitoring and Recording Vital Signs and Images, 246 399 Improvement and Expansion 412 of Manufacturing Simulation Development of a Sugar Cane and Management and Factory Productivity Monitor to Obtain Productivity Floor Supervision Software, for both Maps for Self-propelled Harvesters, 246 the National and International Markets, 241 413 400 Study of the Viability of the Development of a Computerized Development of Software for System for the Management Natural Vulnerability to Pollution of the Fish Production process, 242 in the Physical Environment, 247 401 414 Design of High Performance Development of Cartridge Cryptography Module (HSM), 242 Type Sinterized Metal Filters, 247

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415 425 AbEvo – (Antibodies Evolution). Miniaturized Fluorescence Detection Intelligent System Systems for DNA Analysis, 251 for the Development of Antibodies Based on the 426 Structure of the Antigen, 247 Software for the Registration of Water Supply and Sewage Collection 416 Networks with Space Databases, 252 Production of Human FSH by Recombinant Engineering, 248 427 Development of Injected Graphite Composites 417 Applied in Electrochemical Processes, 252 Research and Development of Construction Process Using Pre-Fabricated Armed Concrete 20th Bidding Instructions Panels Reinforced with Expanded Polystyrene Core: Application for One-Storey Houses, 248 428 Determination of Ferrite Level in Duplex 418 and Superduplex Austenoferritic Stainless Steels, Development of Vitroceramic in Relation to the Variables: Chemical composite for Dental Applications, 249 Composition, Solidification Mode and Thermic Treatment of Solubilization, 252 419 Application of Ceramic 429 Coating on Metal Surfaces, 249 Conformation-Specific Antibodies: Proposal for Generation of Antibodies Directed at 420 Receptors Linked to Active G protein (GPCRs), 253 Production of Adsorbents and Chiral Columns and their use in the Process to 430 Obtain Nantiomerically Enriched Substances Optic Device for Broadband Integrated Access, 253 through Liquid Chromatography, 249 431 421 Study of the Development of Unit for Plasma Technical Viability of a Treatment of Town Refuse, with Piezoelectric Flow Pump, 254 Production of Synthesis Gas, 250 432 422 Process for Manufacture Staged Production of Banana of Gold Artifacts, 254 Seedlings in Three Models of Bioreactor. Challenges of Optimizing the 433 Marriage of Micropropagation Production of Peaches in Regions Techniques for the Supply of with Low Incidence of Cold, 254 Healthy Genetically Improved Banana, 250 434 423 Development of Systems with Use of Cell Culture in Monitoring Toxicity Anti-static Additive and Conductive and in the Investigation of Anti-Tumoral Layers for Development of Transmission Compounds: Evaluation of Cell Death, 250 Belt Used in the Textile Industry, 255 424 435 Airborne System for Acquisition Development of a Temperature and Post-Processing of Images Supervision System for Productive Taken with Digital Cameras, 251 Sectors of Red Ceramic, 255

Translating Research into Business • PARTNERSHIPS FOR TECHNOLOGICAL INNOVATION PITE

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AGRARIAN SCIENCES Institution: School of Agrarian and Veterinary Sciences of Jaboticabal/ Paulista State University (Unesp) Agronomic and Industrial Company: 1 Evaluation of Citrus Varieties Cesp – Cia. Energética de São Paulo Coordinator: Approved value: Luiz Carlos Donadio Company: R$ 154,868 FAPESP: R$ 33,600 / US$ 112,700 Institution: Sum total: R$ 188,468 / US$ 112,700 School of Agrarian and Veterinary Sciences of Jaboticabal / Paulista State University (Unesp) Start: 1/1/1997 Finish: 30/6/1998 Company: Montecitrus Trading S/A The high proliferation of the submerged aquatic Approved value: macrophyte (higher plant) E. densa in the reservoir Company: R$ 18,100 of the Jupiá Hydroelectric Plant (SP) has caused in- FAPESP: R$ 41,800 creasing operational problems for the enterprise. The Sum total: R$ 59,900 research aimed to develop techniques that could be used in their control and it developed into three in- Start: 1/8/1996 terdependent sub-units. The first corresponded to Finish: 31/7/1999 the identification of the species that occur in the re- servoir and to the mapping of their possible ecoty- This research project was aimed at the agrono- pes, using techniques of electrophoresis of isoenzy- mic and industrial evaluation of new varieties and mes and DNA. The second sub-unit corresponded to clones of orange trees, in a partnership between the the work aimed at the development of biological pro- Citrus Culture Experimental Station of Bebedouro grams for the control of E. densa. Fungi were isolated (EECB-SP) and the company Montecitrus Trading. and one of them proved to be capable of controlling Nine varieties of “precocious” orange trees (those the proliferation of E. densa. In the third sub-unit, that give fruit in the north of the State of São Paulo the endeavor was to generate the necessary informa- from July to August) were evaluated, in partial subs- tion for the development of control programs with titution for those currently used in citrus farming, the use of herbicides. An economic and operational with the aim of improving productivity and quality analysis of all the treatments with potential use for of the final product – concentrated orange juice. the control of E. densa was also undertaken. Eight of them showed characteristics close to or even better than those of the Hamlin, presently the most planted precocious variety. The study of the “mid- Food and Agriculture Quality in season” oranges (July to October) involved close to 3 a Market Economy: Organic three dozen varieties, with the Tarocco A and Early Production and the Certifying of Farm Oblong varieties proving to be outstanding. In rela- Products for Obtaining a Green Seal tion to the “late” varieties (September to January), it was concluded that those currently planted – Valên- Coordinator: cia and Natal – show the best advantages. No less Siu Mui Tsai than 150 new varieties of orange trees alone were in- Institution: troduced into the EECB in the period 1997/98, du- Nuclear Energy in Agriculture Center / ring the research, which established data that will University of São Paulo (Cena/USP) serve as a basis for future plantings. Further studies are looking to evaluate close to 250 other varieties. Company: Shimura’s Granja/Shimura Alimentos Ltda. Approved value: Development of a Program for Company: R$ 74,200 the Management of Elodea densa and 2 FAPESP: R$ 115,050 / US$ 56,111.11 Egeria densa in the Jupiá Reservoir Sum total: R$ 189,250 / US$ 56,111.11 Coordinator: Start: 1/7/1998 Robinson Antonio Pitelli Finish: 30/6/2001

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Rural modernization has brought benefits, but at sed to the stages of processing, transportation and the same time social and environmental problems, distribution of the canned product. The present re- such as growing pollution through the intensive use search project aimed to study the properties and of agrochemicals. This project initially aimed to ob- performance of the 900 ml microriveted can, in the tain agricultural commodities (corn and beans) and preserving of edible oil. With the adequate perfor- potatoes through an intensive system of organic pro- mance of the microriveted can for oil proven, the duction (worm humus), with low use of additives market is now offered cheaper packaging with a and at a lower cost when compared to conventional greater capacity to preserve the product than plastic agriculture. Cena/USP and the Microtoxin Labora- containers. Microriveting technology was developed tory of the Luiz de Queiroz Higher School of Agri- by the Kramer Group of Jundiaí (SP). culture (Esalq)/USP continued in their efforts to achieve a qualification for certifying farm products with the official mark of the Green Seal, by means of Development of Technology a comparative analysis of the organic production of 5 Aimed at the Use of beans, corn and potatoes by the company Shimura Derivatives of Yeast in Human Alimentos Ltda. with other conventional production and Animal Foodstuffs of these crops. This project could also serve as a mo- del to make the Brazilian small farm holder econo- Coordinator: mically viable, via the production of clean and certi- Valdemiro Carlos Sgarbieri fied foodstuffs. With the qualification of the Institution: Cena/Esalq laboratories in toxicological analysis, the Food Technology Institute (Ital) opportunity will also be open for interaction bet- ween a teaching and research institution with com- Company: panies which need to have their products qualified. Cooperativa dos Produtores de Cana, Açúcar e Álcool of the State of São Paulo Approved value: Study of the Technical Company: R$ 596,730 4 Viability of Microriveted Cans FAPESP: R$ 62,651 / US$ 18,500 for the Storage Sum total: R$ 659,381 / US$ 18,500 of Edible Vegetable Oil Start: 1/12/1998 Coordinator: Finish: 31/11/2001 Silvia Tondella Dantas The objective of this project was the use of the Institution: biomass of yeast for obtaining modified products Food Technology Institute (Ital) and functional ingredients by means of fractioning Company: in order to obtain derivatives with different chemi- CSN – Companhia Siderúrgica Nacional cal, nutritional and functional properties. The pro- cess followed two schemes: a) the biomass, after Approved value: being cleaned and mechanically broken up and cen- Company: R$ 35,429.03 trifuged, provided a sediment (cellular wall I) and a FAPESP: R$ 5,079.03 / US$ 28,350 clear liquid, which after treatment, resulted in a pre- Sum total: R$ 40,508.06 / US$ 28,350 cipitate (proteic concentrate); b) the biomass, after Start: 1/3/1996 cleaning, was subjected to a process of autolysis so as Finish: 31/7/1997 to obtain autolysed material. This autolysed material underwent two different treatments: one, dehydra- Microriveting, the process of sealing cans which tion in a spray drier (total dehydration of the autoly- allows for a significant reduction in the material sed material), while another part was subjected to used and the use of sheets of low thickness for tops centrifuging in order to obtain a precipitate (Cellu- and bottoms of the cans, is an important technolo- lar wall II) and another clear liquid (extract). The gical development. However, because of its reduced extract could be concentrated so as to obtain a con- dimensions in relation to the traditional system centrated extract, or could be dried in order to ob- used, i.e. conventional riveting, questions arose re- tain a dehydrated extract. The extract, concentrated garding its mechanical resistance and its capacity to or dehydrated, is used in the food industry as an in- guarantee the integrity of the packaging when expo- gredient for nutritional and flavor enhancement.

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The proteic concentrate is used to improve products Environmental Coloring such as meats, breads, soups and sauces. The frac- 7 as a Reproduction Assistant tions, cellular wall I and II, could be used as a sour- and Reducer of ce of soluble fiber and/or thickener/stabilizer for Cannibalism in Matrinxã emulsified or jellified foodstuffs. Coordinator: Gilson Luiz Volpato Increase in the Biomass Institution: of the Eucalyptus Tree by the 6 Botucatu Institute of Biosciences/Unesp Introduction of the CAB Gene via Genetic Modification Company: Fish-Braz Comércio, Coordinator: Importação e Exportação Ltda. Carlos Alberto Labate Approved value: Institution: Company total: R$ 7,145 Luiz de Queiroz Higher FAPESP total: R$ 1,750 School of Agriculture/University Sum total: R$ 8,895 of São Paulo (Esalq/USP) Start: 1/11/1998 Company: Finish: 30/6/1999 Cia. Suzano de Papel e Celulose The matrinxã (Brycon cephalus) is one of the Approved value: main species used in national fish farming, but its Company: R$ 75,127 breeding still poses two fundamental problems: in- FAPESP: R$ 49,930 / US$ 163,791.76 duction of spawning and the high index of canniba- Sum total: R$ 125,057 / US$ 163,791.76 lism in the first days after the hatching of the larvae. Start: 1/7/1998 As in previous studies, we observed that environ- Finish: 30/6/2001 mental coloring affects the aggression and the growth of this species, the present project was set up The objective of this technologically innovative to use environmental coloration (green) to improve project was the genetic modification of commercial their production, as a way of improving the induced hybrids of Eucalyptus grandis and Eucalyptus smith spawning of this species. Furthermore, it was sought with the chimerical pea gene RSLhcb1. To this end, to use environmental coloration (red/blue) to redu- initially different methods of transformation were ce aggression during the initial larvae period, thus tested, using Agrobacterium, bombardment with mi- reducing cannibalism. The results obtained provi- croprojectiles and electroporation of protoplasts. ded clear answers regarding the use of these environ- The research took as its base the results of the ex- mental colors in the production of fresh water sole. pression of that gene in tobacco plants (Nicotiana This process could certainly impact on the building tabacum) and lettuce (Lactuca sativa), which pro- of reproduction and incubating tanks, currently de- moted the increase in the biomass of the modified veloped with colors chosen on the basis of criteria plants, in addition to a series of pleiotropic effects other than the animal’s response. on the morphology, vegetative development and physiology. In conditions of light limitation, trans- genic tobacco plants display greater photosynthetic Evaluation of the Production capacity and synthesis of carbohydrates. Eucalyptus 8 Potential of Embryos in vitro is an ideal culture for applications of this technology, of Cows with High Genetic Value due to its rapid growth and its capacity for vegetati- and Acquired Infertility ve propagation. The economic importance of the production of cellulose and wood as a source of Coordinator: energy demands that new technologies be incorpo- Joaquim Mansano Garcia rated into vegetal improvement system in order to Institution: increase the competitiveness of the Brazilian pro- Agrarian Sciences and Veterinary School of duct on the national and international market. Jaboticabal/Paulista State University (Unesp)

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Company: adequate dispersion of the ration in the fish bree- Gertec Representação, Assessoria ding tanks. It requires no electricity, being operated e Produção de Embriões Ltda. manually, with the dispersion taking place by the hydraulic force deriving from the movement itself, Approved value: nor is experience required for its operation. The Company: R$ 195,180 project aimed to test the efficiency of this equip- FAPESP: R$ 129,700 / US$ 12,351.59 ment, the prototype of which we had already cons- Sum total: R$ R$ 324,880 / US$ 12,351.59 tructed, on two species of fish: pacu or raw tilapia Start: 1/4/1998 (Oreochromis niloticus) and matrinxã (Brycon ce- Finish: 31/3/2001 phalus). Both are unquestionably of commercial va- lue in the Brazilian fish farming industry. The for- Cows with acquired infertility are routinely des- mer species has a gregarious habit, forming shoals. tined to slaughter, without their genetic potential The latter is more aggressive, with a high rate of being totally exploited. Much better use could be cannibalism, though these species represent the two made of these animals in programs of in vitro ferti- main social characteristics among fish. The larvae lization (IVF). In Brazil, there are still no IVF pro- were introduced into their respective tanks and grams aimed at rural producers. For this reason, we their size assessed after 30 and 45 days, whilst bet- proposed a project in conjunction with companies ween the two dates food quantity and feeding time that work in the area of transfer of bovine embryos, were fixed. At the end of the experiment, the survi- for an initial evaluation of the exploitation of the val rate was assessed. embryos of cows with acquired infertility in in vitro production (IVP) and to study the viability of im- planting this methodology in the commercial ambit. Alteration of the 10 Quality of Eucalyptus Wood Food Dispenser for 9 Larvae and Fish Farming Coordinator: of Pacu and Matrinxã Carlos Alberto Labate Institution: Coordinator: Luiz de Queiroz Higher School of Agriculture/ Gilson Luiz Volpato University of São Paulo (Esalq/USP) Institution: Company: Botucatu Institute of Biosciences/ Cia. Suzano de Papel e Celulose Paulista State University (Unesp) Approved value: Company: Company: R$ 770,850.24 Fish-Braz Comércio, Importação FAPESP: R$ 117,691 / US$ 925,350.62 e Exportação Ltda. Sum total: R$ 888,541.24 / US$ 925,350.62 Approved value: Start: 1/7/2002 Company: R$ 23,202 Finish: 30/6/2005 FAPESP: R$ 18,000 Sum total: R$ 41,202 Biotechnology has been revolutionizing human Start: 1/3/2000 activity in the most diverse areas. In the forestry sec- Finish: 28/2/2001 tor technologies are being rapidly incorporated such as transgenics based on studies in genomics, proteo- This project sought to solve an important pro- mics and bioinformatics. The association of biotech- blem in fish farming: how to distribute the ration in nology with conventional programs for the impro- the feeding of larvae adequately. Current methods vement of trees can accelerate the process of are precarious, allowing for high mortality rates, development of products with specific characteris- high competition for food (which leads to large tics. In the paper and cellulose industry, the sourcing growth differentials in individual fish), low growth of trees with a reduced content or altered composi- rates and ration waste. The proposal entailed the in- tion of lignin is one of the examples of the applica- troduction of a device that would carry out a more tion of these technologies. The present project aimed

Translating Research into Business • 39 to modify the quality of eucalyptus wood altering its Development of Molecular composition. The proposal was to obtain a product 12 Markers based on ESTs of Sugar with different chemical properties and physical cha- Cane for Selection of Economically racteristics, enabling a reduction in the costs of the Important Characteristics industrial paper production process. Coordinator: Anete Pereira de Souza FORESTS: Eucalyptus Institution: Genome Sequencing 11 Center for Molecular Biology and Project Consortium Genetic Engineering/State University of Campinas (Unicamp) Coordinator: Helaine Carrer Company: Cooperativa dos Produtores de Cana, Institution: Açúcar e Álcool of the State of São Paulo Luiz de Queiroz Higher School of Agriculture/ University of São Paulo (Esalq/USP) Approved value: Company: R$ 103,675.30 Company: FAPESP: R$172,403 / US$ 42,495.22 Consórcio de Empresas Sum total: R$ 276,078.30 / US$ 42,495.22 Florestais de Papel e Celulose Start: 1/7/2002 Approved value: Finish: 30/6/2005 Company: R$ 1,005,000 FAPESP: US$ 530,000 The project of sequencing ESTs (Sugarcane EST Sum total: R$ 1,005,000 / US$ 530,000 Project - Sucest) in FAPESP’s Genome program has Start: 1/11/2001 already identified around 40 thousand clusters which Finish: 31/10/2003 represent the genes of sugar cane. ESTs have the po- tential to be used in the development of genetic mar- The Eucalyptus Genome project aimed to iden- kers. In this way, microsatellite markers can be obtai- tify 15 thousand genes by means of the sequencing ned from databases of ESTs, and ESTs probes can be of approximately 100 thousand ESTs (Expressed used in RFLP tests for the mapping of QTLs. Bearing Sequence Tags), prepared from libraries of different in mind the advances that should be achieved in the tissues, including plantules, leaves, roots, stems and genetic improvement of sugar cane with the exploita- wood. The EST sequences were recorded automati- tion of the information contained in the ESTs databa- cally and clustered for the identification of the ge- ses, the proposal is, based on these sequences, to deve- nes. By means of the use of bioinformatics, the pro- lop microsatellite, molecular markers of the RFLP ject carried out an analysis of those sequences, type. It is also intended to develop specific markers observing redundancy during the sequencing; the for agronomic characteristics of interest, via conver- (Blast) comparison of the sequences with those de- sion of RFLP markers (hybridized with ESTs probes) posited in international data bases and in the FA- into specific PCR markers (SCARs and STSs). The de- PESP-Genome program; and the clustering of the velopment of these markers will be integrated into a sequences obtained from special programs for data mapping program of the qualitative and quantitative analysis, such as CAP3 and others. In addition, it characteristics that are being developed with the use was endeavored to use the information obtained to of an F1 population, obtained from the crossing of carry out an analysis of the genic expression using two commercial varieties of sugar cane. the microarrays. In this way, it was sought to deve- lop a new technology for the identification of genes involved in the genetic control of the quality of the Identification of Molecular Markers wood and in the resistance to disease and pests, en- 13 Attached to Genes Resistant to Race 1 vironmental stresses and tolerance to nutritional of Oidium (Sphaerotheca fuliginea) and deficiencies. The intention was for this information to Papaya Ringspot Vírus, Watermelon to be made available rapidly to companies for the Strain, in Melon (Cucumis melo) modification of the properties of the wood in in- dustrial use or in other applications. Coordinator: Luis Eduardo Aranha Camargo

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Institution: Company: Luiz de Queiroz Higher School of Agriculture/ Central Bela Vista – University of São Paulo (Esalq/USP) Angus Bela Vista Pecuária Ltda. Company: Approved value: Sakata Seed Sudamerica Ltda. Company: R$ 1,175,000 FAPESP: R$ 730,868 Approved value: Sum total: R$ 1,901,368 Company: R$ 47,800 FAPESP: R$ 118,400 Start: 1/2/2003 Sum total: R$ 166,200 Finish: 31/7/2004 Start: 1/7/2003 The main objective of this project was the iden- Finish: 31/12/2005 tification of bovine genes with a potential for use in the development of new products and technologies Amongst the methodologies used for the identi- to be exploited commercially. In parallel, the infor- fication of molecular markers linked to genes of in- mation created while the work was in progress was terest (in this case, resistance to pathogens), the of inestimable value to the scientific community, no- comparative analysis of almost isogenic strains, tably in the areas of zootechnics, biology, genetic and which differ from each other merely by the presence veterinary medicine, among others. For this purpo- or absence of specific genes, is one of the most effi- se, approximately 100 thousand expressed sequences cient. Two almost isogenic strains of melon, AF-426 (ESTs) were analyzed, obtained from the sequencing (P1) and AF-2196 (P2), contrasting in the absence of libraries of cDNA, prepared with the messenger and presence, respectively, of alleles of resistance to RNA extracted from different organs and bodily tis- Oidium and PRSV-W, are compared using Rapo sue (such as testicles, skin, muscle tissue and adipo- (Random Amplified Polymorphic DNA) and AFLP se tissue). The production of libraries of cDNA fol- (Amplified Fragment Length Polymorphism). These lowed the strategy used by the Sucest project strains, in turn, are compared with AF-125 (P3), the (Sugarcane EST Project), in which the fragments of donor strain of alleles of resistance. Markers present cDNA produced with the SuperScript Plasmid in the resistant converted strain P2 and in the donor System kit (Gibco-BRL) are selected by size in sera- strain P3 and absent in the susceptible recurrent phose column and subsequently cloned in the vec- strain P1 are considered potentially linked to the ge- tors pSport-1 and 6, which were transferred by cells nes of resistance in question. The link between these of Escherichia coli (DH10B strain) by the technique marker candidates and the genes of resistance is con- of electroporation. firmed using a population derived from the retro- crossing (P2 x P1) x P1, which is evaluated for resis- tance to two pathogens, in different experiments BIOLOGICAL SCIENCES conducted in greenhouse conditions. There being a close link between the marker and the gene(s) of re- sistance, the ultimate objective will be to sequence Production of the linked markers and transform them into Scar Botulinic Serum, (Sequence Characterized Amplified Region) type 15 Toxins and Vaccines markers, aiming for their use in programs of genetic improvement to resistance aided by markers. Coordinator: Isaías Raw Sequencing of Institution: 14 Bovine Expressed Butantan Institute Sequence Tags (Best) Company: Solvay Saúde Animal Ltda. Coordinator: Luiz Lehmann Coutinho Approved value: Company total: R$ 25,000 / US$ 150,000 Institution: FAPESP total: R$ 25,000 / US$ 110,000 Luiz de Queiroz Higher School of Agriculture/ Sum total: R$ 50,000 / US$ 260,000 University of São Paulo (Esalq/USP)

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Start: 1/6/1996 In vitro and in vivo Evaluation Finish: 31/12/1999 17 of Nineteen Molecules with High Anti-inflammatory Potential The aim of this project was to develop and set up a unit for the production of botulinic toxins, Coordinator: with a 50 liter fermenter and downstream proces- Gilberto de Nucci sing, aimed at: 1) producing botulinic toxins A, B, Institution: E of medium grade purity intended for the produc- Institute of Biomedical Sciences/ tion of antibotulinic serum for supply to the Natio- University of São Paulo (ICB/USP) nal Health Foundation and the requirements of other countries. The product would be produced Company: by the institute and commercialized by the Funda- Aché Laboratórios Farmacêuticos S/A ção Butantan; 2) producing botulinic anatoxins C Approved value: and D intended, respectively, to immunize birds (or Company: R$ 42,000 / US$ 93,000 horses) and cattle, and to be commercialized by the FAPESP: R$ 140,000 / US$ 90,000 Solvay company; 3) producing botulinic toxins A Sum total: R$ 182,000 / US$ 183,000 and B of high quality for clinical and scientific use. These products would be commercialized by the Start: 1/12/1998 Fundação Butantan. Finish: 30/11/1999

The project aimed to evaluate in vitro and in vivo Project: Construction and laboratory synthesized molecules, with anti-inflam- 16 Operation of a Pilot matory action, leading from there to new medicines. Plant for the Recovery of The in vitro evaluation was carried out, on the one Gallium from Bayer Liquor hand, through the contact of the synthesized molecu- les with the cyclooxygenase enzyme, present in all in- Coordinator: flammatory processes. Tests were carried out on pla- Arthur Pinto Chaves telets of human blood. The in vivo tests were carried out on mice. One of the synthesized molecules displa- Institution: yed positive results in all the in vitro and in vivo tests. Polytechnic School/University of São Paulo (Poli/USP) Company: Purification and Description CBA – Cia. Brasileira de Alumínio 18 of the Antigens of Pork Tapeworms (Taenia crassiceps) for the Approved value: Development of Diagnostic Company: R$ 313,516.91 Reagents for Human Cysticerosis FAPESP: R$ 228,936 / US$ 76,892.79 Sum total: R$ 542,452.91 / US$ 76,892.79 Coordinator: Start: 1/7/1997 Adelaide José Vaz Finish: 30/6/1999 Institution: School of Pharmaceutical Sciences/ The project proposed to design, build and opera- University of São Paulo (USP) te a pilot factory for the extraction of gallium using Bayer liquor. The technology was developed for the Company: extraction of high purity gallium – a strategic metal Biolab-Mérieux S/A in the computer and telecommunications industry Approved value: of high commercial value – using Bayer liquor, one Company: R$ 42,000 of the main waste products from the processing of FAPESP: R$ 33,100 / US$ 8,800 aluminum from bauxite. During the project ionic Sum total: R$ 75,100 / US$ 8,800 resins were also developed for the retrieval of gal- lium from the Bayer liquor and a substance to sepa- Start: 1/12/1997 rate the metal from the resin. Finish: 29/2/2000

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Cysticercosis is a serious problem in the Public This project proposed to carry out a Life Cycle Health system in Brazil, caused by the presence of Analysis (LCA) study of approximately twenty pac- the Taenia solium (Cysticercus cellulosae) larvae in kaging systems in the national market. With finan- the human organism. Frequent locations are the ske- cial support from FAPESP and from a consortium of letal muscle, the ocular system and the central ner- associations and companies, it aimed to identify vous system. The nervous form, neurocysticerosis, is strategic actions for improvements in whatever stage considered to be of the greatest clinical concern. Ho- of the processes involved in the production, use and wever, a safe diagnosis of neurocysticerosis is diffi- final disposal of the packaging, taking into conside- cult due to the large variety of clinical possibilities ration the minimization of its environmental im- and inconsistencies of the symptoms presented. pact. The work was developed using methodology Computerized tomography of the cranium and selected from those available on the international magnetic resonance are currently the techniques market, in accordance with the Society of Environ- that help with the diagnosis. They are, however, very mental Toxicology and Chemistry (Setac), the Envi- expensive and it is not always possible to reach a ronmental Protection Agency (EPA) and ISO 14000 conclusive diagnosis. The immunological evaluation regulations, and from a proposed database of natio- in the serum and its correlation with the cephalo-ra- nal processes and products, which will also contain chidian liquid (CRL) are determining elements in reference information on external markets. The the evolution of the disease. Various techniques have study was applied to packaging systems of some na- been developed as a diagnostic, both through serum tional products, with a significant share of packaging and through LCR, the Elisa test being the method of consumption in the country, with emphasis on the choice. The difficulty of obtaining antigen extracts comparison of the environmental impact of diffe- from naturally infected pigs and the low specificity rent packaging alternatives and in the detection of of the Elisa tests, mainly in serum, indicate the need the critical points of the production processes and to invest in new discoveries. Consequently, the ob- final disposal of the packaging open to improvement jective of this project was to obtain antigens from an and with consequent potential for optimization, thus experimental source, as well as the preparation and contributing to the application of clean technologies purification of antigen fractions for use in rapid and aimed at the sustainable development of the country. low cost testing, which make it possible to detect in- dicators of this disease in the human organism. The research reached its proposed result, and the product Control of Contamination by is now in the improvement stage, prior to being pro- 20 Filamentous Fungi, and Heat Resistant duced on a commercial scale. Actinomycetes in Aseptically Processed Tomato Derivatives

Analysis of the Life Coordinator: 19 Cycle of Packaging for the Pilar Rodriguez de Massaguer Brazilian Market Institution: School of Food Engineering/ Coordinator: State University of Campinas (Unicamp) Luís Fernando Ceribelli Madi Company: Institution: Tetra Pak Ltda. Institute of Food Technology (Ital) Approved value: Company: Company total: R$ 144,022 Fundação de Desenvolvimento FAPESP total: R$ 38,745 / US$ 190,627 da Pesquisa Agropecuária (Fundepag) Sum total: R$ 182,767 / US$ 190,627 Approved value: Start: 1/3/1997 Company: R$ 280,000 / US$ 45,000 Finish: 28/2/1999 FAPESP: R$ 92,800 / US$ 138,200 Sum total: R$ 372,800 / US$ 183,200 This project aimed to quantify and identify the Start: 1/3/1997 flora of mildews and heat resistant actinomycetes in Finish: 28/2/1999 tomato juice and pulp processed aseptically in Tetra Pak packaging and to evaluate the presence of patu- lin and verrucologen mycotoxins in the final pro-

Translating Research into Business • 43 duct of these derivatives. The characteristics were Krahô Project: also determined of the content of residual oxygen, 22 Study of pH and permeability of the packaging that might Medicinal Plants contribute to the development of these microorga- nisms. The study made it possible to establish the Coordinator: sources of contamination and, after the identifica- Elisaldo Luiz de Araújo Carlini tion and selective screening of the most resistant or- Institution: ganisms, the thermal resistance of these mildews was Paulista School of Medicine/Federal evaluated and compared to the resistance of bacte- University of São Paulo (EPM/Unifesp) rial targets normally used to establish the thermal process of acidic foodstuffs (CI. pasteurianum and Company: B. coagulans), using as a substrate the derived toma- Biolab Sanus Farmacêutica Ltda./ to products produced by processing factories. The Eurofarma Labs. Ltda / VYTY-CATI (Krahô) level of sterilization required by the product was es- Approved value: tablished and the re-dimensioned thermal process Company: R$ 238,468 (retention time, temperature) was tested. The pro- FAPESP: R$ 347,550/ US$ 337,900 cesses, once the methodologies of control and quan- Sum total: R$ 586,018/ US$ 337,900 tification were validated, were passed on to the par- ticipating industries. Start: 1/7/2003 Finish: 30/6/2005

Development of The present proposal entailed the continuation 21 a New Class of of the previous project, which focused on an ethno- Anti-Hypertensive pharmacological survey amongst the Krahô Indian ethnic group. In this study, data was obtained on the Coordinator: use of 138 plant species in 292 recipes prescribed for Gilberto de Nucci 51 therapeutic indications, which probably have so- mething to do with the central nervous system. Gi- Institution: ven this wealth of data, it was sought to begin the Institute of Biomedical Sciences/ first pharmacological and phytochemical tests that University of São Paulo (ICB/USP) would enable the investigation of these botanical ex- Company: tracts on laboratory animals in order to discover Laboratórios Biosintética Ltda. new phytotherapics. The studies should extend over the next ten years and will follow a span of collabo- Approved value: ration between eminently national institutions: the Company: R$ 400,000 Federal University of São Paulo (Unifesp), Bio- FAPESP: US$ 474,823.02 lab/Sanus Farmacêutica, Eurofarma Laboratórios Sum total: R$ 400,000 / US$ 474,823.02 and the VYTY-CATI Association, which represents Start: 1/11/2000 the Krahô ethnic group. In addition to this, the pro- Finish: 30/06/2005 ject will receive consultancy from other groups of re- searchers from the country’s universities. In the case The aim of this project is to develop a new class of a phytotherapic resulting from this work, a patent of medicines for the treatment of cardiovascular di- will be sought by the institutions mentioned. seases. This new class of medicines are the aspirina- tes. Basically, this involves attaching a molecule of anti-hypertensive substances (for example atenolol Adaptation for Veterinary Use of and carvedilol) and a calcium antagonist (nimodi- 23 the Type Rabies Antigen in pine) to an aspirin molecule, given that aspirin of- Adhered BHK Cells Used for Humans fers a significant therapeutic effect when administe- red daily in low doses. The immediate advantage Coordinator: would be that the patient, by taking just one pill, Hisako Gondo Higashi would be ingesting a substance in vivo which would Institution: release two important main agents in the treatment Butantan Institute of his disease.

• Translating Research into Business MIGUEL BOYAYAN

EDUARDO CESAR MIGUEL BOYAYAN EDUARDO CESAR

MIGUEL BOYAYAN MIGUEL BOYAYAN

MIGUEL BOYAYAN

EDUARDO CESAR MIGUEL BOYAYAN

EDUARDO CESAR

MIGUEL BOYAYAN 48

Company: The principal aim of the present project was the Produtos Veterinários Ouro Fino Ltda. development of a vaccine for the prevention of rheu- matic fever and other infections caused by type A Approved value: beta hemolytic streptococcus, in partnership with to- Company: R$ 196,675.46 tally national private enterprise. Considering also FAPESP: R$ 196,675.46 the high socioeconomic costs of these pathologies, Sum total: R$ 393,350.92 there is as a final goal the production of an effective Start: 1/11/2004 subunit vaccine, that will offer protection against in- Finish: 31/1/2006 fections from the various serotypes of beta hemoly- tic streptococcus of the group. The vaccine should The production and manufacture of vaccines be, at the same time, safe and incapable of setting off against rabies for veterinary use using technology al- chronic inflammatory or autoimmune reactions, ready developed for human use, of the type rabies such as observed in rheumatic fever. It will use as antigen in adhered BHK cells, is aimed at increasing immunogene, sequences conserved from aminoa- global productivity in response to new market de- cids of the C-terminal region of the M protein. Pro- mands. This involves a relevant technological inno- vided we keep our sights on the reliability and safety vation for the country, insofar as it will create the of the vaccine, its use may be guaranteed in the pre- conditions for a significant increase in competitive- vention of streptococcic infections with possibilities ness in the biological products segment of the Brazi- for applications also in developed countries. lian veterinary market, tending to provoke a subs- tantial drop in the price of these vaccines for the end consumer. This innovation will have a positive im- Microencapsulation of pact on public health, in addition to producing sa- 25 Human Pancreatic Islands and vings for the Ministry of Health, which is responsi- Tissue Engineering as Alternative ble for the vaccination of 19 million dogs in the Treatment for Diabetes Mellitus entire country. The two institutions involved in this project are committed to the proof of concept of Coordinator: production and they should undertake every effort Mari Cleide Sogayar to achieve ideal levels of quality and efficiency of Institution: manufacture on an industrial scale and tests of the Chemistry Institute/University product in the field to comply with the necessary of São Paulo (IQ/USP) steps for the transference of this technology. Company: Biobrás S/A Development of Approved value: Vaccine Against Group A 24 Company: R$ 207,952 Beta Hemolytic Streptococcus FAPESP: R$ 138,200 / US$ 239,378 Sum total: R$ 346,152 / US$ 239,378 Coordinator: Luiza Guilherme Guglielmi Start: 1/2/2000 Finish: 31/1/2004 Institution: Heart Institute (Incor), The isolation, purification and microencapsula- University of São Paulo (USP)/ tion of pancreatic islands constitute a promising al- State of São Paulo Health Secretariat ternative in the treatment of diabetes mellitus (DM). Company: This project aimed: 1) to optimize and perfect the Laboratório Teuto Brasileiro Ltda. isolation, purification and cryopreservation of hu- man pancreatic islands derived from organs taken Approved value: from donor cadavers; 2) to reconstitute the microen- Company: R$ 2,704,840 vironment by means of the co-cultivation of isolated FAPESP: R$ 239,663 / US$ 1,402,960.95 islands with cells of the pancreatic tissue, in the ab- Sum total: R$ 2,944,503 / US$ 1,402,960.95 sence and presence of the extracellular matrix, so as Start: 1/4/2002 to maximize its survival and functionality; 3) to mi- Finish: 31/3/2005 croencapsulate the isolated islands using previously

Translating Research into Business • 49 designed biocompatible materials and/or new mate- be extremely valuable for the improvement pro- rials resulting from tissue engineering; and 4) to gram. This project aims to use the technology of mi- analyze the functional activity of the microencapsu- croarrays of cDNA for the analysis of 6,528 trans- lated islands both in vitro and in vivo. The develop- cripts in contrasting varieties of cane for the ment of this project should permit the creation of accumulation of sugar and subjected to the pre- products (biomaterials for the production of micro- viously mentioned conditions. The project also envi- capsules) and processes (technology for the mi- sages the making up of nylon membranes contai- croencapsulation of pancreatic islands), opening up, ning 3 thousand clones, which will be made available thus, a new and revolutionary treatment perspective to researchers interested in analyzing the response of for diabetic patients. this plant to other phenomena.

Transcriptome of Development of 26 Sugar Cane 27 System for Control of Ant Colonies in Coordinator: Urban Environments Glaucia Mendes Souza Coordinator: Institution: Odair Correa Bueno Chemistry Institute/University of São Paulo (IQ/USP) Institution: Institute of Biosciences of the Paulista Company: State University (Unesp – Rio Claro) Cooperativa dos Produtores de Cana, Açúcar e Álcool of the State of São Paulo Company: e Central de Álcool Lucélia Ltda. Vitex – Agricultura e Pecuária Ltda. Approved value: Approved value: Company: R$ 823,563 Company: R$ 84,600 FAPESP: R$ 493,543 / US$ 82,255 FAPESP: R$ 114,800 Sum total: R$ 1,316,106 / US$ 82,255 Sum total: R$ 199,400 Start: 1/8/2003 Start: 1/4/2003 Finish: 31/7/2005 Finish: 30/3/2006

The production of sugar and alcohol in Brazil Considering that ants are social insects with a would greatly benefit from the introduction of va- very well established division of labor amongst its rieties with a higher content of saccharose and grea- members, the functional unit is the colony as a who- ter resistance to biotic and abiotic stresses. The esta- le and not an ant in isolation. This project proposes blishment of such varieties, using traditional the development of a system involving the use of at- techniques of genetic improvement, is slow. The tractive baits in order to carry out control of colo- process could be accelerated if the target genes for nies of the species that have the status of pest. Al- the improvement were identified. The recent se- though the use of baits has a long history in the quencing of 237 thousand sugar cane ESTs (Expres- control of pests, there is today renewed interest in sed Sequence Tags) offers the opportunity to study their application, something which is due to several its levels of expression on a large scale, using the factors. Amongst them, pressure from public opi- technology of microarrays of cDNA. The analysis of nion for a reduction in the use of insecticides, the re- the transcriptome of contrasting varieties of high quirement for a correct evaluation of the ideal insec- and low sugar content using DNA chips, could indi- ticide to be used and the increase in the safety of the cate genes involved in the induction of the accumu- applicators and the users. The proposal for the deve- lation of saccharose throughout the maturation of lopment of an efficient system for the control of ant the plant, pointing the way to the genetic manipula- colonies based on knowledge acquired in basic re- tion of this gramineum. In addition to this, a global search involves two paths: to act on research aimed analysis of the transcriptome of this plant subjected at providing assistance to technological develop- to insect attacks, to interactions with endophytic ment and to provide a basis for the legalization of bacteria, to hydric stress, among other factors, would the final product.

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HEALTH SCIENCES Institution: Bauru School of Dentistry/ University of São Paulo (USP) Development of a Company: 28 Transference Mold – Kunzel Brasil Equipamentos Odontológicos Ltda. Zanetti Technique Approved value: Coordinator: Company: R$ 582,000 Artêmio Luiz Zanetti FAPESP: R$ 307,637 / US$ 158,160.20 Sum total: R$ 889,637 / US$ 158,160.20 Institution: Bauru School of Dentistry/ Start: 1/9/1998 University of São Paulo (USP) Finish: 31/8/2001

Company: The aim of the present project was to promote Teccom Industrial e Comercial the development of products aimed at the huge mar- de Equipamentos Ltda. ket of Brazilians with missing teeth and/or localized Approved value: bone loss. The second generation of this product Company: R$ 96,250 should replace, with advantages, previously available FAPESP: R$ 194,000 products. Its goal was the fast production of a varia- Sum total: R$ 290,250 tion of the system of implants with innovative cha- racteristics and the production of substances for Start: 1/3/1998 bone regeneration – reabsorbable membrane and Finish: 28/2/2001 inorganic bovine bone –, as well as amelogenin, a product with cemental regeneration capacity, and The aim was to develop a new method for sim- bone morphogenetic protein (BMPs). plifying and giving greater precision in the moun- ting of models of the upper dental arch, in semi or totally adjustable articulations. The project presen- EXACT AND EARTH SCIENCES ted a new technique in molding, obtaining, transfe- rence and mounting of the plaster model in the ar- ticulating device, in any case that demands the use Implementation of a of an articulator for the diagnosis and planning of 30 Telemedicine and Medical Practice patient treatment. The project had as its final objec- Support Network Covering tive the development of a so-called transference the Whole Brazilian Territory mold, with which one is able to transfer the measu- rements of the upper arch of the patient to the arti- Coordinator: culator in a single stage, without the need to elabo- Álvaro Garcia Neto rate bases of measurement and orientation plans, and without the use of the facial arc fork and two Institution: halves of the transference of the model. During the São Carlos Institute of Physics/ execution of the project, at the stainless steel phase, University of São Paulo (USP) prototypes were developed due to the complexity of Company: the various anthropometric standards that exist wi- Unimed – Participações S/C Ltda. thin the country. Approved value: Company: R$ 333,072 Development of FAPESP: R$ 168,722.54 / US$ 40,407.46 29 Optimized Implants for Sum total: R$ 501,794.54 / US$ 40,407.46 the Areas of Low Bone Start: 1/3/1996 Density and Products for Finish: 28/2/1998 Bone Regeneration The use of computer networks is one of the mo- Coordinator: dern-day revolutions. With this in mind, Unimed Aguinaldo Campos Junior approached the universities for guidance as to how

Translating Research into Business • 51 to make best use of them. In September 1993, an ve action to be taken quickly. In order to do this, agreement was signed between the São Carlos Insti- specific hardware and software were configured, tute of Physics and Chemistry of the University of and equipment was developed, dedicated to the São Paulo, via the Foundation for the Support of constant assessment of the control parameters of Physics and Chemistry, and Unimed Participações. the film processors, and another for the assessment, This agreement resulted in Brazil’s first network to in the field, of the geometrical characteristics of the use the TCP/IP protocol via satellite (VSAT), which focal points of X-ray tubes, based on a CCD came- has 43 points of presence, spread throughout the ra. All the performance tests of the equipment car- Brazilian territory. These points constitute the net- ried out periodically were automated, with the use work backbone. The objective of this second project of suitable instrumentation, controlled by portable was to expand this backbone to the 250-plus remai- microcomputers. ning points (Unimed affiliates), to form UniRed, in order to provide telemedicine services (access to in- formation, new techniques, continuous training, pu- Project and Implementation blication of periodicals, bibliographical research) 32 of an Automatic Grammar Reviser and medical practice support services (virtual doc- for the Portuguese Language tors on duty distributed by area of medical specialty and electronic mail). Coordinator: Maria das Graças Volpe Nunes Institution: Development of Remote São Carlos Institute of Mathematical Management System for Quality 31 Sciences /University of São Paulo (USP) Control Programs in Imaging Diagnosis Departments Company: Itautec-Philco S/A Coordinator: Approved value: Jean Albert Bodinaud Company: R$ 78,000 Institution: FAPESP: R$ 17,954 / US$ 9,200 Institute of Electrotechnics and Energy/ Sum total: R$ 95,954 / US$ 9,200 University of São Paulo (USP) Start: 1/10/1997 Company: Finish: 30/9/1998 Unidade Radiológica Paulista Clínica de Diagnóstico por Imagens The research aimed to carry out studies in com- putational linguistics for the production of a new Approved value: version of Itautec-Philco S/A’s Grammatical Reviser, Company: R$ 39,500 / US$ 12,600 which is now on the market. The original version, FAPESP: R$ 20,852 / US$ 131,186.54 which included automatic syntactic analysis and Sum total: R$ 60,352 / US$ 143,786.54 corrected several kinds of errors, was perfected, fol- Start: 1/3/1998 lowing the creation of rules to avoid lexical ambigui- Finish: 28/2/2001 ties and ambiguities in syntactical structures. In or- der to do this, studies were undertaken of the written The objective of quality assurance in imaging Portuguese language in a corpus (a body of texts) of diagnosis is to optimize the quantity of clinically over 35 million words. Besides serving for the crea- useful information in the radiological images, while tion of the rules, the study of the corpus made it reducing doses of radiation and minimizing opera- possible to extend the process of identifying the er- tional costs. This project aimed to develop a com- rors frequently committed by users of secondary puter communications network, over which part of school level, making the Grammatical Reviser suita- the data used in this kind of assessment would be ble for its target public, namely secretaries and offi- sent, several times a day, via Internet, to a center for ce workers in general. In this new version, the Gram- the reception, storage and analysis of data, located matical Reviser works coupled with an online in the Institute of Electro-techniques and Energy grammar, which supplies contextualized grammati- (IEE-USP). In addition, the network would have a cal assistance, based on the difficulties identified in system for sending performance reports in real time the correction of the text by the user himself. The to the management of the clinics, allowing correcti- implementation of the online grammar was an im-

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portant part of the project. The work was carried out dustries and aircraft pilots; and b) “hybrid intelligent with the support of a multidisciplinary team of lin- systems”, for supporting operation and control, and guists, and computing professionals who were al- real time systems, both in the petrochemical and in ready working in collaboration. the aeronautical industries; and c) the development of dynamic sites for the Internet, for Ministry of Science and Technology (amongst others). Pilot Training System: 33 Aircraft Cabin Simulator Application of Plasma Torches Coordinator: 34 in Steel-making Processes Alexandre Carlos Brandão Ramos Coordinator: Institution: Aruy Marotta Technological Aeronautics Institute/ Aerospace Technical Center (ITA/CTA) Institution: Gleb Wataghin Physics Institute / Company: State University of Campinas (Unicamp) Laboratório de Informática Aplicada (LIA) Company: Approved value: Villares Metals S/A Company: R$ 106,000 FAPESP: R$ 97,980 Approved value: Sum total: R$ 203,980 Company: R$ 371,403 FAPESP: R$ 310,500 / US$ 305,000 Start: 1/4/1999 Sum total: R$ 681,903 / US$ 305,000 Finish: 31/3/2001 Start: 1/9/1999 There are at the moment two quite different Finish: 31/8/2002 kinds of simulator for aircraft pilots: 1) the flight si- mulator properly speaking, an extremely expensive This project set out to develop plasma torch hea- piece of equipment, which accurately represents all ting technology for the 3-ton steel distributor of the the movements made by the aircraft, and 2) the com- continuous casting system at Villares Metals S/A. It is puter simulator, with software similar to computer a known fact that the stability of the temperature of games and a low cost, where the pilot verifies the air- the steel brought about by the plasma torch in the craft’s behavior without having the real three-dimen- distributor, coupled with an inert atmosphere on the sional impression of piloting the plane. The aircraft surface of the liquid metal, has a beneficial effect on cockpit simulator that was the object of this project the quality of the steel, with less segregation and a comes somewhere between these two extremes, as it more homogeneous structure of equiaxial grains. Ex- is a low-cost piece of equipment, comprising a three- perience in other countries has shown that the sys- dimensional representation of an aircraft cockpit and tem of plasma in the distributor may offset, within a software that simulates the instruments and main range of +/-1°C, fluctuations in temperature between systems. In this kind of simulator, there is no cabin or one trip and another of the crucible of up to +/-20°C. joystick while piloting the airplane, and the pilot only The most appropriate settings of the torch and the simulates the operation of some of the systems. A distributor were studied, the level of potency of the system is already used for pilot training, that combi- torch required to keep the temperature of the steel nes two important stages in one system: 1) the within desired limits for a given mass of liquid metal, ground school, where the pilot learns to recognize and the effect of the plasma assessed on the quality of the physical location of the instruments, the different the steel and the savings in the process. subdivisions of the control panel, and the check list sequences, and 2) CPT, where the pilot learns the va- rious operating procedures in normal, abnormal and Development of High Power Lasers emergency situations. Currently, researchers from the 35 with Emission in the Spectral Region Laboratory of Applied Information Technology – of 800 to 1000 nm, Based on Hetero LIA, together with teachers from the Technological Structures of GaAs/InGaAsP/InGaP Institute of Aeronautics/ITA, are conducting research into a) the area of “intelligent tutor systems”,applied Coordinator: to the training of operators in the petrochemical in- Wilson de Carvalho Junior

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Institution: The present research project had the objective of Center for Research and Development developing Mathematical Programming solvers es- in Telecommunications and Brazilian pecially adapted for the optimization of RBAF – Association for Synchrotron Light Row Block Angular Form and NRBAF – Nested Row Agreement/Convênio CPqD-ABTLuS Block Angular Form. The project adapted and im- plemented the structural method developed by the Company: researcher responsible for it as part of his thesis for a AsGa Microeletrônica S/A doctorate at Cornell University. This method is pre- Approved value: sented in the article “J.M. Stern and S.A. Vavasis, Ac- Company: R$ 105,900 tive Set Methods for Problems in Column Block An- FAPESP: R$ 49,500 / US$ 124,180 gular Form, Com.Appl.Math”, v. 12, p. 199-226, Sum total: R$ 155,400 / US$ 124,180 1994. The solvers were to replace commercial solvers Start: 1/3/1999 (OSL-IBM) in the MultiFor and DyFor computer Finish: 28/2/2001 programs (software) in UniSoma. This software with an industrial application solves optimization pro- This project sought to develop the manufacture blems of multiple mixtures, with an RBAF structure, of an encapsulated prototype of a powerful laser and multiperiod optimization problems, with an with emission in 808 nm, based on heterostructures NRBAF structure. of GaAs/InGaAsP/InGaP. The performance charac- teristics of the device were adapted to the applica- tions for use in medical equipment and in Nd:YAG New Inorganic and Hybrid laser pumping. It was also sought to make viable the 37 Phosphate-based Pigments manufacture of lasers with emissions in 880 and 980 nm, aiming at applications in the pumping of solid Coordinator: state lasers and telecommunications. The performan- Fernando Galembeck ce characteristics envisaged were: 2 W of power in Institution: continuous mode (cw) with operating current of 3- Chemistry Institute/State 5 A, spectral width around 2 nm and beam divergen- University of Campinas (IQ/Unicamp) ce in the range of 40º and 10º in directions perpen- Company: dicular and parallel to the active region, respectively. Serrana de Mineração Ltda. The project involved the collaboration of the labora- tory of the Optoeletrônica do Convênio Fundação Approved value: CPqD/ABTLuS, based in Campinas (SP), with AsGa Company: R$ 67,340 Microeletrônica, a business located in Paulínia (SP). FAPESP: R$ 25,915.30 / US$ 107,132.70 Sum total: R$ 93,255.30 / US$ 107,132.70 Start: 1/3/1996 High Performance Solver for Finish: 31/8/1997 36 Structured Optimization Problems The objective of this project was the development Coordinator: of two new classes of pigment and of the respective Julio Michael Stern manufacturing processes. This involves white pig- Institution: ments and colored pigments, both based on phospha- Institute of Mathematics and Statistics / tes (condensed or not) of metal ions: aluminum, cal- University of São Paulo (IME/USP) cium, iron and others. These new pigments are intended, on the one hand, to replace titanium dioxi- Company: de in white paints and, on the other, to fill other gaps UniSoma Matemática para Produtividade S/A in the availability of colored pigments, of high optical Approved value: quality and enhanced chemical stability in the envi- Company: R$ 188,000 ronment. Due to their chemical nature, all the pro- FAPESP: R$ 96,000 ducts in question should be exempt from problems of Sum total: R$ 284,000 toxicity. Their production and disposal will be effected Start: 1/10/1996 without creating new environmental problems and Finish: 31/1/1999 without increasing existing problems. Processes were used which have been the subject of patent requests,

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lodged by the requesting group; production opera- ReGra Project: New Challenges for tions on a pilot scale have been carried out at the pre- 39 Automatic Grammar Revision mises of the interested company since June 1995. Coordinator: Maria das Graças Volpe Nunes Continuous Production Institution: of Fuel Alcohol Using 38 São Carlos Institute of Mathematical Saccharomyces cerevisiae Sciences/ University of São Paulo (USP) Supported by Chrysotile Company: Coordinator: Itautec Philco S/A Inês Joekes Approved value: Institution: Company: R$ 214,620 Chemistry Institute/State FAPESP: R$ 67,500 University of Campinas (IQ/Unicamp) Sum total: R$ 282,120 Company: Start: 1/3/2001 Sama – Mineração de Amianto Ltda. Finish: 28/2/2003 Approved value: ReGra is a grammatical reviser for Brazilian Por- Company: R$ 287,610 tuguese that is regarded as the most wide-ranging FAPESP: R$ 71,527 / US$ 62,464.61 and efficient of its category on the market. Microsoft Sum total: R$ 359,137 / US$ 62,464.61 acquired a license from Itautec-Philco, the co-spon- Start: 1/1/1999 sor of the project, and today makes ReGra available Finish: 31/12/2000 through its Office 2000 package, ensuring world- wide distribution. The ReGra Project was honored This technological innovation project refers to with two prizes, the Pawn of Technology, awarded by the obtaining of fuel alcohol by a continuous process the São Carlos High Technology Park Foundation, in based on sugar cane, using Saccharomyces cerevisiae 1998, and the Alcatel National Prize for Technologi- supported by chrysotile, with a view to its industrial cal Innovation, in 1999. This very positive scenario implementation to replace the traditional process, may give the impression that the quality of gramma- whether in batches or semi-continuous. The indus- tical revision by ReGra had now reached satisfactory trial implementation of a continuous process has levels, and that the development, properly speaking, long been a target pursued by the productive sector, of the reviser had been concluded. However, tests since it means a reduction in installation and opera- showed that ReGra’s current performance still fell ting costs, and makes it possible to automate the considerably short of what was desirable, with a sig- line, thereby allowing a reduction in the price of the nificant number of omissions (39.48 per cent of all ethanol produced. This price reduction is funda- the incorrect sentences were not corrected) and of mental for making ethanol competitive with gasoli- unwanted actions by the tool (there were 1.03 incor- ne. The heart of the continuous process for this in- rect actions for each correct action). Therefore there dustrial sector is the existence of a chemically, still existed ample margin for work on improve- mechanically and biologically stable supported ca- ments, which resulted in a far greater evolution than talyzer. We achieved a catalyzer supported by Sac- had actually been observed. This evolution deman- charomyces cerevisiae on chrysotile, in which the cells ded efforts to improve the current reviser, but – more bind, are not removed, and acquire heat tolerance importantly – it called for a change of paradigm, and display activity for up to one year after their pre- both in the use of linguistic strategies and in compu- paration. Bench tests of fermentation with fixed bed ter implementation, in particular because the perfor- reactors, using selected strains, showed efficiency mance of the current version had practically reached and productivity considerably superior to the best its peak in the approach adopted up to this moment. values obtained with free cells operating in a conti- It proved to be indispensable for the strategies used nuous system for up to one month. Fixed beds are in ReGra to be revised, and for new modules to be not, however, the most suitable in project enginee- added to the existing ones for the revision of texts, in ring. There still has to be an increase in scale to con- order to expand the number of correct actions of the firm whether the increases in efficiency and produc- tool, and, consequently, to reduce the number of its tivity are maintained. omissions and over-corrections.

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Development of a Approved value: 40 Differential GPS System for Company: R$ 3,572,800 / US$ 105,000 Positioning and Guidance FAPESP: R$ 1,665,000 / US$ 1,150,000 of Aircraft in Real Time Sum total: R$ 5,237,800 / US$ 1,255,000 Start: 1/1/2002 Coordinator: Finish: 31/12/2004 Helio Koiti Kuga Institution: The aim of this project was the integration of in- National Institute for Space Research (Inpe) novative technologies for high performance aircraft by means of the creation of a nucleus for the mecha- Company: nics of Computational Fluid Dynamics (CFD). The Embraer – Empresa Brasileira de Aeronáutica S/A development of this project was to enable Embraer Approved value: to acquire expertise in the area of CFD, enabling it to Company: R$ 583,586 function in a similar manner to its competitors and FAPESP: R$ 67,935 / US$ 218,117 to obtain productivity gains and technological inno- Sum total: R$ 651,521 / US$ 218,117 vation. At the present time, the market offers high Start: 1/3/2002 performance computers with a competitive cost-be- Finish: 31/8/2003 nefit relationship. At the same time, the current ma- turity of advanced methods of CFD permits its in- This project was aimed at the application of new corporation in technological application. These precise methods of trajectography and guidance in factors, together with the high level of expertise in real time to increase the productivity of landing and Brazilian research, could allow the convergence and take-off attempts and aircraft noise. The work invol- the incorporation of latest generation knowledge, ved the development of: 1) a Differential Global Po- techniques and methods for the application of CFD sitioning System (DGPS) which makes it possible to in the development of high performance aircraft. determine on board, with precision and in real time, The making available of state-of-the-art computa- the position of the aircraft in a system of coordina- tional resources, currently non existent in the coun- tes; 2) a guidance system which offers the pilot, in try, should also permit the continued development real time, information which permits the overflight in the research and teaching institutions and promo- of previously defined points under desired condi- te the consolidation of parallel computing techni- tions, within the precisions required by certification; ques, with positive impacts on scientific productivity and 3) a complete and integrated project covering in the area of the mechanics of computational fluids. the means necessary for the implementation of the Differential Global Positioning System (antennae, RF, telemetry, real time processing, processors, com- Identification of Derivatives of munications boards and interfaces) aimed at reuse 42 Stability and Control Of Aircraft via in various aircraft and bases. Non-Linear Filtering and Stochastic Optimization: Algorithms and Data Application from Test Flights Application of 41 Advanced Computational Coordinator: Fluid Dynamics for High Luiz Carlos Sandoval Góes Performance Aircraft Institution: Technological Aeronautics Institute/ Coordinator: Aerospace Technical Center (ITA/CTA) João Luiz Filgueiras de Azevedo Company: Institution: Embraer – Empresa Brasileira de Aeronáutica S/A Technological Aeronautics Institute/ Approved value: Aerospace Technical Center (ITA/CTA) Company: R$ 908,237.50 Company: FAPESP: R$ 121,995 / US$ 195,525.05 Embraer – Empresa Brasileira de Aeronáutica S/A Sum total: R$ 1,030,232.50 / US$ 195,525.05

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Start: 1/1/2002 area have been directed towards improved perfor- Finish: 30/6/2003 mance and durability of both kinds of prosthesis (they are suitable for specific situations). In the case This project permitted the complete dynamic of mechanical prostheses, there are no domestic ma- modeling, that is to say, the determination of the nufacturers nor does the necessary technology exist dynamic parameters and of the aerodynamic deriva- in Brazil: the development of this technology was tives and of the control of aircraft on the basis of test one of the targets of this project. In the case of bio- flights. Embraer currently uses static techniques for prostheses, the objective of this work was to develop the determination of these parameters, which does new techniques for reticulating the bovine pericar- not permit the identification of complete models and dium. The expectation was to achieve more homo- requires the use of theoretical data, of tunnel trials, genous materials, resulting in significant improve- and even exhaustive manual adjustment by trial and ments in the mechanical and biological properties. error. With the mastery of the modern techniques of For mechanical valves, the main objective was to try dynamic systems identification, the company will be to meet the repressed market demand, which is asso- able to make use of more representative data from ciated with the scientific and technological challenge the aircraft, which will save time and allow it to redu- of making a structure in titanium alloys, covered ce the cycle of development, notably with respect to with carbonous materials, widely used in orthopedic control systems, such as automatic pilot, yaw damper prostheses, in association with a covering of hemo- and other systems for increasing stability. This pro- compatible materials, in particular collagen. ject was aimed at the application of new numerical, algorithmic methods and experimental techniques for test flights to increase the productivity and relia- Optical Fiber Catheter for the bility of the dynamic and aerodynamic modeling tri- 44 Diagnosis of Atheromatosis Platelets als for fixed wing jet aircraft. in the Cardiovascular System

Coordinator: ENGINEERING Renato Amaro Zangaro Institution: Institute of Exact Sciences and Technology/ Program for the Development and University of Vale do Paraíba (Univap) 43 Construction of Mechanical Heart Valves and from Bovine Pericardium Company: Tecnobio Ltda. Coordinator: Approved value: Gilberto Goissis Company: R$ 150,000 Institution: FAPESP: R$ 30,800 / US$ 98,982.03 São Carlos Institute of Chemistry/ Sum total: R$ 180,000 / US$ 98,982.03 University of São Paulo (IQ/USP) Start: 1/8/1998 Company: Finish: 31/7/2000 Braile Biomédica Indústria, Comércio e Representações Ltda. Techniques based on Raman spectroscopy and fluorescence spectroscopy, also known as “optical Approved value: biopsy”, have proven themselves to be potential Company: R$ 84,624 / US$ 4,545 substitutes for conventional histology. This entails a FAPESP: R$ 33,636 / US$ 47,564 form of spectral analysis followed by a processing via Sum total: R$ 118,260 / US$ 52,109 software which enables the identification of the na- Start: 1/1/1997 ture of deposits occurring on the coronary walls. Ac- Finish: 31/12/1998 cess to different regions of the body by laser radia- tion and the collection of the generated signal next Heart valves are vulnerable to pathologies of se- to the tissue have proved to be one of the great tech- veral etiologies that severely jeopardize the cardio- nological obstacles to this technique becoming defi- vascular system. Solutions for these complications nitively established. In the present case, namely, in generally include valve replacements using mechani- the diagnosis of in vivo coronary pathologies, ano- cal or biological prostheses. Developments in this malies are looked for in the wall of the arteries. This

Translating Research into Business • 57 proposal was based on the study of the different pa- Institution: rameters that involve a fiber optic catheter, in order Polytechnic School/University to design and build one with a lateral view which, via of São Paulo (Poli/USP) laser radiation, enables it to stimulate an internal co- Company: ronary wall, and to pick up in an efficient manner Owens Corning Fiberglas A S. Ltda. the Raman scattering generated by this same tissue. This catheter should be part of a piece of equipment Approved value: that enables a diagnosis, in the first instance, and, in Company: R$ 414,962.62 a second stage, the destruction of the platelets for- FAPESP: R$ 13,900 / US$ 196,651.60 med, avoiding perforation of the arteries. Sum total: R$ 428,862.62 / US$ 196,651.60 Start: 1/11/1996 Finish: 31/10/1999 Development of Technology 45 for Two- and Three- Dimensional The various stages of this research project cove- Aerodynamic Trials for High red a diagnosis of the market and of the technology Performance Aircraft Project for the production of fiber glass components, a diag- nosis of alternative applications for steel mill clinker, Coordinator: the development of cement from clinker, a study of Olympio Achilles de Faria Mello the cost and the choice of the cement, the durability Institution: of the composites and the development of the pa- Technological Aeronautics Institute/ nels, as well as the dissemination and transfer of Aerospace Technical Center (ITA/CTA) technology. The project succeeded in developing a new kind of low alkaline cement, in which clinker is Company: the basic component, which also contains activators Embraer - Empresa Brasileira de Aeronáutica S/A and E-type fiberglass. Panels were obtained with an application in the construction of walls, ceilings, Approved value: floors and partitions. The project is at the stage of Company: R$ 3,704,000 passing on the technology to industry, for commer- FAPESP: R$ 1,894,300 / US$ 948,479.42 cial scale production. The project opens up the pos- Sum total: R$ 5,598,300 / US$ 948,479.42 sibility of alternative markets for blast furnace clin- Start: 1/6/2001 ker and the use of E-type glass fiber. Finish: 31/5/2004

This project is aimed at the application of new Development of methods to increase the productivity and reliability 47 Technology for the of low velocity aerodynamic tests carried out in Bra- Manufacture of Fibro-cement zil, as well as new methods for two-dimensional and Tiles without Asbestos three-dimensional tests, in order to provide the cor- responding support to our aeronautical industry, so Coordinator: that it can develop new aerodynamic profiles and Holmer Savastano Junior wing configurations, and obtain performance gains Institution: – and, consequently, an increase in competitiveness School of Zootechnics – on a time scale compatible with market realities. and Food Engineering/ The innovation proposed here was of an incremen- University of São Paulo (USP) tal type, so as to fine tune, by means of a series of ac- tions, the services of subsonic aerodynamic tests ne- Company: cessary for the design of aircraft. Permatex Ltda. e Imbralit Ltda. Approved value: Company: R$ 1,576,560 Panels of Cement from Clinker FAPESP: R$ 213,749 / US$ 95,496.33 46 Reinforced with Fiber Glass E (E-GRC) Sum total: R$: 1,790,309 / US$ 95,496.33 Coordinator: Start: 1/8/2001 Vahan Agopyan Finish: 31/7/2003

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The main objective of this research was to develop Start: 1/4/1998 a new technology for the production of cement tiles Finish: 30/9/1999 reinforced with cellulose and plastic fibers, for the production of tiles by the modified Hatschek process. The Brazilian fruit and vegetable market, in ad- The international trend in the civil engineering and dition to being highly competitive and risky, displays building market is for competition based on new a high index of product loss (in the order of 12.3 technology for composites. On the other hand, the million tons). Therefore, it is essential not only to Brazilian building industry, in its residential, indus- produce fruit and vegetables of high quality, but also trial and farming sectors, is showing a robust demand to adopt correct techniques of handling, packaging for low cost systems, with a rational use of labor and and transport, so that the products reach the consu- reduction of waste. Also to be observed is the world- mer in the best possible state of conservation and so wide tendency for the use in the building industry of that a reduction is achieved in the index of loss. materials reinforced with fibers, as they offer the pos- Thus, it is indispensable to use packaging systems sibility to produce slim components, in addition to suitable for each type of product. The objective of enhanced energy absorption when struck by sharp this project was to develop packaging systems appro- forces. Cellulosic fibers are a renewable raw material priate for seven types of fruit and vegetable products that has been accepted internationally for over 20 and suitable for our distribution and transport sys- years, in countries such as Australia and the United tem. Corrugated cardboard combines several cha- States. In developing countries too, natural fibers have racteristics as a packaging material for market garde- aroused interest, as reinforcement for fragile cement- ners and was to be used in the project. In addition to based matrixes, due to their low cost, their availability the packaging, the project also sought to develop se- in wood and also fibrous plants, due to the possibility ven technical manuals, one for each product, presen- of using fibers considered sub-products of other ap- ting the systems developed. plications (rope-making, textile industry, paper in- dustry), due to energy savings, and also to environ- mental issues. With adaptations, these fibers are Automated System for suitable for production on Hatschek equipment. The 49 Security Copies and the Recovery principal stages of this study comprised the formula- of Backup/Restore Files tion of the fibrous composite, through the selection on Heterogeneous Platforms and preparation of the fibers and the cement matrix; advice on the adaptation of a Hatschek-type indus- Coordinator: trial production line, in each partner company; the Antonio Marcos Aguirra Massola determination of the mechanical, physical, chemical Institution: and microstructural properties of the new material; Polytechnic School/University and the verification of the acceptable performance of of São Paulo (Poli/USP) the materials and of their durability. Company: Perrotti Informática Com., Imp. e Exp. Ltda. Development of Corrugated Approved value: 48 Cardboard Packaging Systems Company: R$ 275,000 for Fruit and Vegetables FAPESP: R$ 54,700 Sum total: R$ 329,700 Coordinator: Luís Fernando Ceribelli Madi Start: 1/3/1996 Finish: 31/5/1997 Institution: Institute of Food Technology (Ital) The objective of this project was to develop an Company: automated system for file backup and restoration on Associação Brasileira do heterogeneous platforms. The research resulted in Papelão Ondulado – ABPO the development of the EBS - Enterprise Backup System – a piece of backup software to be deployed Approved value: mainly in corporate environments and which opera- Company: R$ 41,040 te over a network of totally interconnected compu- FAPESP: US$ 52,520 ters of various sizes. Sum total: R$ 41,040 / US$ 52,520

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System for the Visual and/or result in benefits of tens of millions of dollars. This 50 Sound Location of project, therefore, was aimed at the optimization of Fixed or Moving Objects the operation of the company’s refineries, focusing on the three main aspects of the control structure: Coordinator: the actions to maintain the process close to ideal Wilhelmus Adrianus Maria Van Noije conditions, restrictions over safety, quality, etc., and the level of optimization, at which are defined the Institution: optimum conditions for the operation of the equip- Polytechnic School/University ment and processes which constitute an oil refinery of São Paulo (Poli/USP) – including the function of production planning. As Company: a product of this work, it was intended to offer to Pe- Microline – Multiplexadores de R.F. Ltda. trobras, for application in its refineries, a suite of software programs that would be able to interact in Approved value: real time with all levels in the control of production, Company: R$ 37,500 / US$ 1,000 from planning up to predictive control. FAPESP: R$ 55,900 / US$ 5,000 Sum total: R$ 93,400 / US$ 6,000 Start: 1/10/1997 Optimization and Advanced Control Finish: 30/9/1998 52 of the Cyclohexanol Reactor at Rhodia’s Chemical Plant in Paulinia The objective of this research project was to de- velop a system which would enable objects to be lo- Coordinator: cated remotely, whether they were fixed or in mo- Rubens Maciel Filho tion. Generally speaking, the objects are located by Institution: means of a signaling device associated with them School of Chemical Engineering/ which, when activated, enables the identification State University of Campinas (Unicamp) and location of a specific object contained within a Company: certain perimeter. Rhodia S/A Approved value: Development of Integrated Company: R$ 340,600 51 Optimization of the Units FAPESP: R$ 25,800 / US$ 20,000 of an Oil Refinery Sum total: R$ 366,400 / US$ 20,000 Start: 1/8/1996 Coordinator: Finish: 31/7/1998 Claudio Augusto Oller do Nascimento Institution: The cyclohexanol reactor is an important piece of Polytechnic School/University equipment for several chemical routines at the Pauli- of São Paulo (Poli/USP) nia Chemical Plant (SP), as cyclohexanol is an inter- mediate item for a great number of products of com- Company: mercial interest. This is a catalytic process based on Petrobras – Petróleo Brasileiro S/A the hydrogenation of phenol, in a multistage reactor. Approved value: In this context, this project aimed: 1) to develop and Company: R$ 573,522 validate a deterministic mathematical model for the FAPESP: R$ 22,000 / US$ 167,951 cyclohexanol reactor; 2) to develop a methodology Sum total: R$ 595,522 / US$ 167,951 and a procedure for obtaining operational policies Start: 1/7/1997 for the Paulinia Chemical Plant cyclohexanol reactor, Finish: 30/6/2000 through the use of non-linear deterministic optimi- zation techniques and factorial planning; 3) to deve- Petrobras has ten oil refineries which process the lop control structures and algorithms and implement equivalent of several billions of dollars per year. Im- them in the cyclohexanol reactor. Two algorithms ba- provements in the strategies for the control and sed on the concepts of DMC (Dynamic Matrix Con- planning of the operation of these refineries could trol) and STR (Self-Tuning Regulator) were assessed,

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initially by simulation, and, subsequently, implemen- Development of a ted in real time in the reactor. 54 Polymerization Process for the Production of Polymers with Low Prumo – Project of Mobile Residual Monomer Content 53 Units for Technological Assistance for Micro and Coordinator: Small Businesses (MSBs) Reinaldo Giudice Institution: Coordinator: Polytechnic School/University Vicente Nelson Giovanni Mazzarella of São Paulo (Poli/USP) Institution: Company: Institute of Technological Research Rhodia Brasil Ltda. of the State of São Paulo (IPT) Approved value: Company: Company: R$ 135,000 Serviço Brasileiro de Apoio às Micro FAPESP: R$ 55,000 / US$ 259,000 e Pequenas Empresas – São Paulo (Sebrae–SP) Sum total: R$ 190,000 / US$ 259,000 Approved value: Start: 1/1/1999 Company: R$ 1,182,000 Finish: 31/12/2000 FAPESP: R$ 94,847 / US$ 253,992 Sum total: R$ 1,276,847 / US$ 253,992 The objective of this research was to develop Start: 1/5/1998 polymerization processes in which the end product Finish: 30/4/2000 had a reduced content of free monomer, without sa- crificing the productivity of the process. The innova- With organized and programmed action to sup- tion consisted of acting on the polymerization pro- port micro and small businesses (MSBs) on their cess through the use of new initiators and additives, own premises, the plan was – with the use of batte- as well as of strategies for adding raw materials du- ries of tests, analyses, on-the-spot control experi- ring the process and of temperature variations. This ments and examinations – to detect faults in raw made it possible to reduce the process periods asso- materials, equipment and processes, and to indicate ciated with the extraction of the residual monomer the necessary modifications, implementing them, and to diminish the losses of monomer in this sepa- whenever possible, expeditiously, as a didactic tool ration. The objective was to meet and to surpass in- with as much visibility and effectiveness as possible. ternational standards relating to permitted levels of These dynamics for support should result in inno- volatile compounds in the product. The technology vations, both in processes and in the formulation of in use then was based on the extraction by steam, the components of the raw materials and in the pro- which affects productivity with an additional stage, perties of the end products. These activities will be and creates effluents that have to be treated. delivered via Prumo, which consists of mobile labo- ratory units (MU), operated by specialized engi- neers and technicians. The in loco technological as- Development of sistance is expected to last between one and three 55 Electric Steels days. During this period, a survey will also be car- ried out to identify problems that are common to Coordinator: the sector and afterwards themes for cooperative re- Fernando José Gomes Landgraf search, with several MSBs taking part, will be pro- Institution: posed. Management problems may be attended to Institute of Technological Research at a later stage, possibly by Sebrae or other qualified of the State of São Paulo (IPT) institutions. To start with, this proposal will be ap- plied to the plastics transformation sector. Company: CSN – Companhia Siderúrgica Nacional

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Approved value: The objective of the present project was the de- Company: R$ 74,500 / US$ 80,000 velopment of better technology for converting lig- FAPESP: R$ 88,474.53 / US$ 43,793.73 nocellulosics (residue or otherwise) and virgin or Sum total: R$ 162,974.53 / US$ 123,793.73 recycled thermoplastics into environmentally friendly products. The main technologies studied Start: 1/3/1996 were: the formation of a mantel by deposition by air Finish: 28/2/1997 (non-woven) and mixture by melting (extrusion and injection of mixtures). The steps of the project The innovations expected from this project were consisted of developing methods to convert ligno- aimed at establishing the technology for the manu- cellulosic residue (newspapers, sugar cane bagasse facture of two new kinds of steels for electromagne- and sawdust) mixed with thermoplastics (poly- tic purposes, combining the experience of resear- propylene, polyethylene and polystyrene); optimi- chers from CSN – Companhia Siderúrgica Nacional zing laboratory methods for producing composites and of the IPT – Institute of Technological Research. for the automobile industry, using residue; setting The characteristics of the two groups that were the up a database for various natural fibers (jute, sisal, objective of this project – Type of steel: high loss; Sta- ramie, coconut, curauá [a kind of fibrous brome- ge: certification; Losses (W/kg) 1.5 t/60 Hz/0.5 mm: liad], pineapple, linen, sugar cane bagasse, etc.) in 7.5; Permeability (B50(t)): 1.78. Type of steel: me- different proportions and formulations, aimed at dium loss; Stage: exploratory; Losses (W/kg) 1.5 t/60 better adhesion and mechanical and physical pro- Hz/0.5 mm: 5.8; Permeability (B50(t)): 1.74. The perties; establishing the extent of the recycling pro- project provided for the experimental investigation cesses of these composites and quantifying the losses of the effect of some variables in the processing on of properties, and analyzing their life cycle, in parti- the magnetic properties of the steel sheets, with the cular with regard to the automobile industry. The aim of attaining the above mentioned values of elec- composites were assessed for their mechanical pro- trical losses and magnetic permeability. Steel with perties (flexion, tension), impact (IZOD) and physi- better magnetic properties leads to electric motors cal properties (swelling and accelerated aging). that perform better. Support from FAPESP made it possible to construct a system of magnetic measure- ments and to add new competencies to the teams Development of the from the IPT (a new methodology of magnetic tes- Production of High Speed ting, the “separation of losses”), widening the range 57 Steel Rolls for Hot Strip Rolling of services that the institute can offer and giving the team deeper insight into the relations between pro- Coordinator: cessing, microstructure and magnetic properties. Amilton Sinatora Institution: Production of Compounds Polytechnic School/University 56 Based on Natural Fibers for Use of São Paulo (Poli/USP) in the Automobile Industry Company: Aços Villares S/A Coordinator: Alcides Lopes Leão Approved value: Company: R$ 467,700 Institution: FAPESP: R$ 145,475 / US$ 30,850 Botucatu School of Agricultural Sciences / Sum total: R$ 613,175 / US$ 30,850 Paulista State University (Unesp) Start: 1/12/1997 Company: Finish: 30/11/1999 Toro Indústria e Comércio Ltda. Approved value: The objective was the production of cast high- Company: R$ 728,350 speed steel rolls for hot strip rolling, with a perfor- FAPESP: R$ 145,750 mance superior to that shown by the rolls currently Sum total: R$ 874,100 made in Brazil. The targets of the project were: a) to produce high-speed steel rolls for hot strip rolling Start: 1/3/1997 with a competitive advantage of at least 10 per cent, Finish: 28/2/1999 in terms of the cost/benefit coefficient, compared

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with the products currently produced in Brazil; b) to rolling. With the integration of this unit with an attain reliability and reproducibility in the manufac- electric steel works or an LD, both capital investment turing process (levels of rejects lower than 5 per cent and operating costs can be reduced, resulting in high of the total of rolls produced). The activities of esta- productivity and shorter times for order comple- blishing the bases of the research project were car- tion. The main argument in favor of the producti- ried out at the premises of the Metallurgy Division vity of this type of plant is savings achieved. of the IPT and of the Laboratory of Superficial Phe- nomena of the Mechanical Engineering Department of Epusp, as well as in Villares’s roll factory. The pi- Development of a Test lot production of rolls was carried out at the same 59 Methodology for Alloys that factory, in Pindamonhangaba (SP), with subsequent Resist Carburetion and operation in the steel mills, followed by analyses of Catastrophic Carburetion their behavior and performance. Coordinator: Zehbour Panossian Study of the Process Institution: of Continuous 58 Institute of Technological Research Casting of Thin Plates of the State of São Paulo (IPT) Coordinator: Company: Rezende Gomes dos Santos Engemassa Engenharia e Materiais Ltda. Institution: Approved value: School of Mechanical Engineering / Company: R$ 170,401 State University of Campinas (Unicamp) FAPESP: R$ 27,146 / US$ 50,760.75 Sum total: R$ 197,547 / US$ 50,760.75 Company: CST – Cia. Siderúrgica de Tubarão Start: 1/5/2000 Finish: 30/4/2003 Approved value: Company: R$ 80,000 The objective of this project was to develop a test FAPESP: R$ 160,000 / US$ 25,500 methodology for assessing the behavior of alloys Sum total: R$ 240,000 / US$ 25,500 that resist heat, under conditions in which the phe- Start: 1/7/1997 nomena of carburetion, catastrophic carburetion Finish: 30/6/1999 and fluidity are acting simultaneously. Furthermore, it aimed to increase the degree of mastery over the Steel mills the whole world over seek to put into effects of the chemical composition of alloys that re- operation the process of continuous casting integra- sist heat and of the characteristics of the application ted with rolling, in view of the possible significant of these alloys on the phenomena of carburetion and cost reductions that this would bring about, notably catastrophic carburetion. It also aimed to increase due to the great reduction in energy consumed. This knowledge of the mechanisms for the occurrence of integration would also provide for a marked impro- this latter phenomenon. The target is to set up a vement in the quality of the products, in view of the “ranking” of the performance of the heat resisting reduction in the stages of the process: the reheating alloys produced by Villares, related to the demands of the plate would be eliminated. In addition to the involving carburetion, catastrophic carburetion and construction of new micro-mills, it is known that fluidity. It provides for two series of experiments in- the market shows the possibility of some integrated volving heat resisting alloys marketed by the com- mills incorporating a thin plate rolling machine next pany: tests to assess the susceptibility to carburetion to the LD converter. At the moment, the process of and to catastrophic carburetion, using a gaseous car- the continuous casting of thin plate is the most ac- bonizing atmosphere with test bodies positioned in- cepted solution amongst the Near-Net-Shaping Cas- side a tubular oven, and tests to assess the behavior ting processes. One of the advantages of the conti- of the alloys, when they are submitted simulta- nuous casting of thin plate is the possibility of neously to carburetion and fluidity, with cast tubes coupling together the continuous casting and the positioned in a fluidity testing machine.

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Synthesis and Characterization of Institution: 60 Advanced Carbonous Materials Gleb Wataghin Institute of Physics/ State University of Campinas (Unicamp) Coordinator: Company: Carlos Alberto Luengo Eaton Ltda. - Divisão de Transmissões Institution: Approved value: Physics Institute/State Company: R$ 1,133,000 / US$ 40,000 University of Campinas (Unicamp) FAPESP: R$ 488,300 / US$ 155,120.70 Company: Sum total: R$ 1,621,300 / US$ 195,120.70 Usiminas Start: 1/7/2001 Approved value: Finish: 30/6/2003 Company: R$ 410,000 FAPESP: R$ 292,032.90 The nitriding of metals is a process that makes it Sum total: R$ 702,032.90 possible to alter the properties of surface hardness, wear, corrosion and heat resistance of the material. Start: 1/5/1995 In order of importance, it is used in the treatment of Finish: 31/12/1998 ferrous metals, refractory metals, and, more recently, aluminum. The process of nitriding surfaces is ap- The objective of this integrated research was the plied, amongst others, in the mechanical, automobi- synthesis and characterization of Advanced Carbo- le and hydraulic industries, in the deformation of nous Materials (ACM), working on Brazilian raw metals, foundries, steel making, biomedicine and materials to reach new developments in the area. In foodstuffs. The process is used in the treatment of the first instance, a separation was carried out of the plastic injection molds, of automobile parts (valves, undesirable phases present in coal tar and a suitable gears, pistons, etc.), aluminum extrusion molds, choice of residue from the distillation of petroleum tools for the cutting and milling of metals, puncture to obtain middle stage pitch. This pitch was synthe- of matrixes for cutting generally, treatment of pros- sized through heat treatments of distillation/poly- theses, etc. In the last two decades, there has been merization, taking as a comparative standard the re- progress in the technology used in the processes for sults of the characterizations of imported middle treatment of surfaces, in particular with the develop- stage pitch. The next stage was the conversion of the ment of the method of nitriding by plasma in a va- middle stage pitch, both the imported pitch and the cuum oven and methods of ionic implantation. one produced in the course of the research project, Thermo-chemical treatment by plasma offers va- into ACM products, such as carbon fiber, carbon- rious advantages when compared with the traditio- carbon compound, microsphere of mesocarbon, nal methods nitriding by salt bath or gaseous nitri- synthetic graphite and carbon 60, with the conse- ding. Studies carried out recently, comparing the quent development of processes for each kind of various methods of nitriding, show that it is possible material. The delicate microscopic arrangements in- to improve the metallurgical properties of the metals volved in the formation of the middle stage pitch considerably, using implantation with a beam of and later treatments (up to the final products) called ions and nitriding with intensified plasma. for the use of advanced characterization techniques, such as polymerized optic light microscopy, nuclear magnetic resonance, X-ray diffraction and infra-red Development of a New spectroscopy with Fourier transforms, to determine Synthesis Process of Polypropylene the degree and the type of condensation of the aro- 62 with High Resistance to Melting matic structures. Coordinator: Ademar Benévolo Lugão Industrial Applications of Nitriding 61 Methods with Plasma Ovens and Ionic Institution: Implantation for the Treatment of Steels Institute of Energy and Used in Car Transmission Systems Nuclear Research (Ipen) Company: Coordinator: OPP Petroquímica Daniel Wisnivesky

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Approved value: go to the companies’ premises, carrying out tests, Company: R$ 136,000 examinations and experiments, diagnosing pro- FAPESP: R$ 36,500 / US$ 67,360 blems and/or detecting possible faults and presen- Sum total: R$ 172,500 / US$ 67,360 ting solutions. The project also intended to identify technological problems in the sector, not solvable Start: 1/11/1999 through the MUs, translating them into a set of the- Finish: 31/10/2001 mes of common interest to a certain number of MSBs, developing work proposals for these compa- The main applications of HMS-PP are: extrusion nies and identifying possible development agencies of plates, films, thermo-formation, coatings, foams for financing these projects. The project was develo- and blowing. The participation of PP in these seg- ped by the IPT – Institute of Technological Research ments has been limited by its low resistance to mel- of the State of São Paulo S. A., in partnership with ting, which prevents or jeopardizes these processes. Sebrae/SP and with the support of associations from These applications represent a market of over 1 mil- the sector of the treatment of surfaces. lion tons in the Northern Hemisphere. In Brazil, OPP estimates that the market for this is around 30,000 tons. The objective of this work was to deve- lop the process of synthesizing HMS-PP based on Parallelization of the the original process put forward by Ipen. 64 Adjustment of the Background of Production in Management Networks Using PVM PRUMO – Projects of Mobile 63 Units for Technological Assistance Coordinator: for Micro and Small Businesses (MSBs) Denis José Schiozer of the Surface Treatment Sector Institution: School of Mechanical Engineering/ Coordinator: State University of Campinas (Unicamp) Zehbour Panossian Company: Institution: Petrobras – Petróleo Brasileiro S/A Institute of Technological Research of the State of São Paulo (IPT) Approved value: Company: R$ 261,000 Company: FAPESP: R$ 1,383.40 / US$ 160,989.60 Serviço Brasileiro de Apoio às Micro e Sum total: R$ 262,383.40 / US$ 160,989.60 Pequenas Empresas – São Paulo (Sebrae–SP) Start: 1/6/1996 Approved value: Finish: 31/5/1999 Company: R$ 972,720 FAPESP: R$ 107,084 e US$ 104,660.43 This research project aimed to develop a system Sum total: R$ 1,079,804 / US$ 104,660.43 and to qualify professionals in the area of parallel Start: 1/5/2001 computing in a network of using PVM Finish: 30/4/2003 and the oil fields’ numerical simulators. It was ini- tially developed on a network of workstations at Prumo – the Project of Mobile Units for Techno- Unicamp, and used the Black-Oil simulator of logical Assistance – is an original proposal that aims, CMG, IMEX. The project was divided basically into through an innovative work dynamic, to achieve in- four stages. In the first three, the objective was to de- cremental innovations in micro and small busines- velop a methodology capable of facilitating the work ses (MSBs), to create the conditions for productive of the engineer in adjusting the background of pe- processes to evolve, and, possibly, of diagnosing op- troleum production. At the end of the third stage, portunities for radical innovations, that may bring the engineer should have, in real time a little more about changes in the technological level in the sector than the equivalent of a run of a simulator, a sensiti- assisted. Essentially, the project consisted of a pro- vity study of one of the chosen parameters. At the gram of technological assistance for the micro and end of these three stages, there will also be a study small company – MSBs, lasting from one to three intended to choose the best architecture for this kind days, through mobile laboratory units (MUs), which of problem. The last stage is intended for the appli-

Translating Research into Business • 65 cation of the results obtained in the previous stages, ment, applied to the remelting of aluminum refuse extending the project to a more complex problem, (IPT), and in the study for optimization of recycling which may be the parallelization of the semi-auto- processes (Epusp) and included the comparative matic adjustment of production backgrounds, or study of two techniques for the heating of the reco- methods of optimization for the choice of alternati- very furnace: heating with an electric arc (plasma) ves for production. This definition will depend on and by oxy-gas. Besides the recycling of aluminum, the results obtained beforehand. With the techno- the project pursued the prospective study of the re- logy acquired in the area, the results should also be use of the solid residue generated by the process, as extended to other network architectures and other raw material for refractory products, abrasives oil field simulators. and/or white ceramics. The project involved the as- sembly of a recovery furnace with a nominal capa- city of 100 kg/h, the operation of this equipment in Recycling of Aluminum: the processing of waste from different origins with 65 Development of two alternative sources of energy; the analytic moni- Technological Innovations toring of the process, with a view to studying the va- riables in the process and the assessment of the per- Coordinator: formance of each alternative. The project also Antonio Carlos da Cruz provided for a technical/economic study to be car- Institution: ried out, aiming to scale the equipment for the capa- Institute for Technological Research/State city needed to meet the industrial demand for the of São Paulo Secretariat for Science,Technology treatment of these residues. and Economic Development (IPT/SCTDESP) Company: Strategic Reorganization Associação Brasileira do Alumínio – Abal 66 and Technological Innovation Approved value: in the Product Line Company: R$ 192,700 FAPESP: R$ 161,924 / US$ 129,107.36 Coordinator: Sum total: R$ 354,624 / US$ 129,107.36 Alfredo Colenci Junior Start: 1/7/2000 Institution: Finish: 30/6/2002 São Carlos School of Engineering/ University of São Paulo (USP) The conventional process for the recovery of alu- Company: minum is based on the heating of the recovery fur- Chocolates Finos Serrazul Ltda. naces by means of air/oil combustion. To increase Approved value: the metallurgical yield of this process, there is an ad- Company: R$ 59,300 dition of salts (NACI and KCI) to the load, in a pro- FAPESP: R$ 65,300 portion of between 10 and 40 kg for each 100 kg of Sum total: R$ 124,600 residue processed. These salts are easily lixiviated by water, and, for this reason, they call for the disposal Start: 1/9/1998 of the residue from the process (black sludge) in in- Finish: 31/8/2000 dustrial landfills. Due to its high cost, this practice is not always observed, above all by small businesses In the market for almost 50 years, Chocolates Fi- from the sector. In addition, the conventional pro- nos Serrazul Ltda. has been going through a key mo- cess is highly pollutant, due to the presence of salt ment in its existence, under pressure from the forces vapors in the exhaust gases. As they are corrosive, of the so-called globalized market. In response to these vapors cause the premature wear of the gas this, it has made investments in two simultaneous cleaning equipment and a consequent increase in and inseparable directions: management and tech- processing costs. The project’s main objective was to nology, in order to realign itself and redefine its ac- research and develop a clean (without the use of tivities in the sector. In strategic terms, it should gra- salts) process of its own for recycling aluminum. The dually abandon the production of intermediate project made use of the previous experience of its industrial goods, such as the granulated and coating proponents, in the development of similar equip- lines, and act in the line of finished chocolate pro-

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ducts, such as Easter eggs and fine chocolates (diffe- tions were tested on top of the covering of a building rentiated and personalized), ceasing to act at levels with dimensions of 5 m x 6 m that had cracks and as of “increasing diseconomies”, to act at levels of “in- a consequence let water leak through. Suitable tech- creasing economies” with products of higher added niques were developed for the application of the sys- value. In terms of technology, the improvements cal- tem. The field experiment proved that the proposed led for go as far as a refinement in the manufactu- system is effective in eliminating infiltration in cove- ring process and a systematic search for new sources rings, as well as being economically and environ- and specifications of raw materials, which will be mentally appropriate. carried out under the technological and helping control of specialists. Development 68 of a Reactor for Evaluation of the Recycling Sterilizing Waste Water 67 of Industrial Residues Derived from the Synthesis of Styrene Coordinators: and the Rolling of Metallic Gilberto de Martino Jannuzzi / Aluminum, with a View to their Roberto Feijó de Figueiredo Application in the Protection of the Institution: Covering of Civil Constructions School of Mechanical Engineering/ State University of Campinas (Unicamp) Coordinator: Fazal Hussain Chaudhry Company: NCR Esterilização D´Água por UV Ltda. Institution: São Carlos School of Engineering/ Approved value: University of São Paulo (USP) Company: R$ 48,000 FAPESP: R$ 36,025 Company: Sum total: R$ 84,025 Martinez & Micheloni Ltda. Start: 1/6/1998 Approved value: Finish: 31/5/2000 Company: R$ 7,320 FAPESP: R$ 16,025 / US$ 399 This is a project to adapt an already existing tech- Sum total: R$ 23,345 / US$ 399 nology for the sterilization of drinking water, and to Start: 1/1/2/1997 use it in a system for treating waste water. The prac- Finish: 30/6/1998 tice of treating sewage in Brazil is still in its infancy, and the intention was to make a contribution towards Industrial activities generate a variety of sub- a solution of this problem. Specific objectives: the products in great quantities, which often mean was- construction of a prototype reactor for sterilizing te requiring disposal. This fact is even truer in the waste water, using a collection point in Unicamp’s case of petrochemical industries, where these waste Hospital de Clínicas, monitoring the performance of products do not follow a consistent pattern. The the equipment and analyzing its bactericidal powers, purpose of this project was to test the use of sub- and doing a cost/benefit analysis of the equipment. products from the synthesis of styrene and from the Initially, the quality of the in-going water was ascer- manufacture of telephone cables, to be used, in an tained by measuring its main physical, chemical and innovative technology, as protection for the cove- bacteriological parameters. Secondly, an attempt was rings of buildings. This technology exploits the ad- made to determine any preliminary treatment prior hesive quality of the resin and the impermeability of to making use of the sterilization system. Next, tests the compound, discarded by the cable industry, were carried out with the prototype reactor using ul- made up of two layers of a copolymer on both sides traviolet lamps to sterilize the waste water, and bac- of a rolled aluminum product. The feasibility of this teriological analyses (and possible alterations to the technology was initially tested over a small concrete prototype), and tests with different levels of flow, slab to which the resin/compound system was ap- and, finally, an analysis of the economic feasibility of plied. The properties of the system in field condi- the treatment system.

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Geochronology Laboratory with Institution: 69 High Resolution Ionic Microprobe: Lorean School of Chemical Engineering – Support for Development of State of São Paulo Secretariat for Science, High Technology Geoscientific Technology and Economic Development Projects in Oil Exploration Company: Rhodia Brasil Ltda. Coordinator: Colombo Celso Gaeta Tassinari Approved value: Company: R$ 64,997 Institution: FAPESP: R$ 35,850 / US$ 1,120 Institute of Geosciences / Sum total: R$ 100,847 / US$ 1,120 University of São Paulo (USP) Start: 1/7/2002 Company: Finish: 30/6/2003 Petrobras - Petróleo Brasileiro S.A. Approved value: The main objective of this project was to develop Company total: R$ 1,500,000 hydrophobic and or hydrophobic-hydrophilic co- FAPESP total: R$ 1,500,000 polymers using as comonomers styrene, methylsty- Sum total: R$ 3,000,000 rene, methyl-metacrylate, butyl acrylate, acrylic acid and acrylonitril for use as additives in plastics for Start: 1/2/2005 different applications. These copolymers (additives) Finish: 31/1/2008 are added to plastics and elastomers to improve some of their properties, such as thermic resistance, The objective of this project is the implementa- dispersion, moldability and density, among others. tion of a Geochronological Laboratory with a high Polymers formed by styrene, alphamethylstyrene resolution ionic microprobe on the campus of the and methyl-metacrylate are used as additives for University of São Paulo (USP), in the city of São plastics aiming for an increase in flexibility without Paulo. The proposal is to develop, in the area of altering their thermic resistance and as elastomers, geosciences, projects geared towards the explora- adhesives and sealants, to confer a high degree of tion/exploitation of oil. They should be related to moldability, among other characteristics, to foams. the study of the source of the sediments forming the It was sought to control the characteristics of the co- reservoir bedrocks and to the study of the precise da- polymers, such as composition (monomer ratio and ting of diagenetic processes and of the characteriza- their distribution in the chain) and molecular tion of the tectonic evolution of potentially oil-bea- weight by means of the adjustment of the parame- ring sedimentary basins. The project will also train ters involved in the copolymerization reactions: flow human resources in high geoscientific technology of reagents, temperature of reaction, agitation and geared to applications in the oil industry in order to nature of the solvents (polarity, pH and ionic force). meet market demand. It is important to highlight In this manner different polymers were sought with that the implementation of the laboratory will af- physico-chemical properties compatible with the ford technological innovations in other areas, such different applications previously mentioned. as in the study of the evolution of the continents and in the mineral industry. In addition to Petrobras and USP, the São Paulo State University (Unesp) and the Properties of Mixed State University of Campinas (Unicamp) will also be Systems Prepared from partners in this work. 71 Mixtures of Carrageenans and Tensoactives

Synthesis and Characterization Coordinator: 70 of Copolymers of Maria Elisabete Darbello Zaniquelli Alphamethylstyrene-Styrene Aimed at its Application in Institution: the Encapsulation of Silica Particles School of Philosophy, Science and Arts/University of São Paulo (USP – Ribeirão Preto, SP) Coordinator: Company: Amilton Martins dos Santos Rhodia Brasil Ltda

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Approved value: Approved value: Company: R$ 75,538 Company: R$ 50,505 FAPESP: R$ 22,700 FAPESP: R$ 14,200 Sum total: R$ 98,238 Sum total: R$ 64,705 Start: 1/12/2002 Start: 1/7/2002 Finish: 30/11/2003 Finish: 30/6/2003

Carrageenans are a special type of polysacchari- The project developed a predictive safe and suita- de extracted from seaweed which reveal units of ga- ble methodology for the formulation of industrial lactose and variable substitution of sulfated groups. solvents for the solubilization of crystalline solids. In this way they behave like polyanions. Owing to The proposal was, in the first instance, to apply the their great affinity with water, carrageenans belong Hansen methodology, originally developed for poly- to the group of hydrocolloids, in which gelatins and mers, to systems with polar polymers and crystalline other gums are also included. They are used as dis- solids, using experimental data on the solubility of persal, jelling and thickening agents, principally in solids in solvents. Data on the solubility of solids of the food industry. The present project studied the interest was acquired. A computer program was de- interaction of some fractions of carrageenans with veloped to obtain the parameters of solubility of the synthetic tensoactives with the aim of understan- solid based on experimental information. In addi- ding: 1) the formation of possible polyelectrolyte- tion, the creation of two alternative methodologies tensoactive complexes; 2) the variation in the jelling for predicting the solubility of solids was proposed. capacity through the introduction of low molar The first calculates the solubility using the parame- mass tensoactives in the presence of different elec- ters estimated on the basis of the experimental data. trolytes; and 3) the separation of phases caused by The second predicts the solubility on the basis of the the mixture with tensoactives and the determination thermodynamic criterion of solid-liquid equili- of the microstructure. In parallel, chemical modifi- brium, using the Unifac model. Software was develo- cations were carried out on carrageenan molecules ped encompassing all the methodologies worked on. with the aim of obtaining fractions with some am- phiphilic character. The carrageenans, modified or not, were characterized in relation to the type and Prumo – Project of proportion of contra-ions, size exclusion chromato- 73 Mobile Units for Technological graphy, RMN, FTIR and finally HPLC. The results Assistance for Micro and obtained in this project, in addition to their funda- Small Businesses in the Wooden mental scientific aspect, may contribute to the broa- Furniture Making Sector dening of the application of carrageenans in diffe- in the State of São Paulo rent formulations, such as the cosmetic and pharmaceutical areas. Coordinator: Takashi Yojo Institution: Prediction and Institute of Technological Research 72 Solubility of Polar of the State of São Paulo (IPT) Polymers and Crystalline Solids in Solvent Mixtures Company: Serviço Brasileiro de Apoio às Micro Coordinator: e Pequenas Empresas – São Paulo (Sebrae–SP) Martín Aznar Approved value: Institution: Company: R$ 972,700.00 School of Chemical Engineering/ FAPESP: R$ 472,855 State University of Campinas (Unicamp) Sum total: R$ 1,445,555 Company: Start: 1/7/2004 Rhodia Brasil Ltda. Finish: 30/5/2006

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With organized and programmed action to sup- conformation stage, and it is done by the same com- port micro and small businesses in their own premi- pany that carries it out. In this case, the post-treat- ses, it is planned – using a battery of tests, analyses ment of the phosphatized layers consists of the ap- and examinations – to detect deficiencies in raw ma- plication of a lubricant without anticorrosive terials, equipment and processes and to indicate the properties, since there is practically no waiting time necessary modifications, implementing them, whe- between the application of the phosphatized layer rever possible, as a didactic tool of maximum viabi- and the conformation operation. However, although lity and efficiency. This dynamic of assistance should not very common, phosphatization can be carried result in innovations both in the process and in the out by the company supplying the metal sheets. This formulation of the components of the raw materials situation occurs in Brasmetal, which sells steel sheets and in the properties of the final products. This ac- already phosphatized and lubricated, ready for cut- tion is delivered by means of Prumo, which consists ting and conformation. Thus, the post-treatment of of mobile laboratory units (MUs) operated by spe- the phosphatized layers must take into account the cialized engineers and technicians. The in loco assis- possible occurrence of corrosion of the sheets in the tance is intended to last from one to three days. In storage and transport phases. Therefore, a lubricant this project, the focus of the proposal is on the fur- with anticorrosive properties should be applied or niture making sector, aiming for an improvement in some other product should be applied over the lu- its production processes and products. A survey will bricant that will protect the phosphatized and lubri- be undertaken to identify problems common to the cated sheet. The aim of this project is to carry out a sector and to detect any organizational, manage- systematic study for the purposes of correlating the ment and operational deficiencies the micro and performance of different phosphatized layers with small businesses . The project is developed by IPT in different lubricants aiming for the mechanical con- partnership with Sebrae-SP and with the support of formation of phosphatized layers. the furniture making sector.

Behavior of Study of the 75 Aeronautical Materials 74 Influence of the Characteristics and Structures of Phosphated Layers in Subjected to Impact Stamping Operations with and without Lubricants Coordinator: Marcílio Alves Coordinator: Institution: Zehbour Panossian Polytechnic School/University Institution: of São Paulo (Poli/USP) Institute of Technological Research Company: of the State of São Paulo (IPT) Embraer - Empresa Brasileira de Aeronáutica S/A Company: Approved value: Brasmetal Waelzholz Indústria e Comércio Company: R$ 261,900 / US$ 57,580 Approved value: FAPESP: R$ 367,896 Company: R$ 160,889.96 Sum total: R$ 629,796 / US$ 57,580 FAPESP: R$ 113,710 Start: 1/6/2003 Sum total: R$ 274,599.96 Finish: 30/11/2005 Start: 1/2/2005 Finish: 31/1/2007 The purpose of this project is to undertake the technological development that will allow Embraer Phosphatized layers on ferrous metals are used, to simulate and analyze the response of aeronauti- among other purposes, to facilitate conformation cal structures when subjected to impact. The sha- operations with the use of the traditional zinc phos- pes of the impacting projectiles include extremely phate-based baths. Normally the application process hard spheres and flexible bodies which mimic the of the phosphatized layers immediately precedes the impact of small fragments and birds respectively.

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The projectiles are fired against aeronautical struc- solidate its position in the State’s economy. With the tures and the various impact tests provide assistan- implementation of the MUs and the methodology to ce for the simulations to be undertaken. In order to be applied, it was sought to achieve a technological proceed to numerical analysis, the mechanical pro- increment in the sector. Since there is a period of stay perties of the material that makes up the structure in the companies assisted, we may consider that the- under evaluation are determined by means of static se laboratory units fit into the company routine and dynamic traction tests, covering a range of 0 to being able, in the making of shoes, to substitute raw 5.000/s of deformation rate. The project also pro- materials and alter production processes in pursuit of poses the development of the theoretical model of accumulated improvements. Thus, the companies failure based on the mechanics of damage to pre- can minimize production costs, direct their purcha- dict the failure of the material in impact situations. ses towards better quality products, increase produc- The model considers the effect of large deforma- tivity and avoid reworking and rejects, among other tions, temperature and rate of deformation and items of relevance to micro and small businesses. will be implemented and tested alongside the expe- rimental results in the program of finite elements used in the analyses. Prumo – Project of 77 Mobile Units for Technological Assistance for Micro and Prumo – Project of Small Businesses in the Industrial 76 Mobile Units for Technological Sector of Plastics Transformation Assistance for Micro and Small Businesses in the Coordinator: Shoemaking Sector Armênio Gomes Pinto of the State of São Paulo Institution: (Franca-Birigüi-Jaú) Institute of Technological Research of the State of São Paulo (IPT) Coordinator: Kléber de Barros Company: Serviço Brasileiro de Apoio às Micro Institution: e Pequenas Empresas – São Paulo (Sebrae–SP)) Institute of Technological Research of the State of São Paulo (IPT) Approved value: Company: R$ 946,220 Company: FAPESP: R$ 170,000 / US$ 223,664.69 Serviço Brasileiro de Apoio às Micro Sum total: R$ 1,116,220 / US$ 223,664.69 e Pequenas Empresas – São Paulo (Sebrae–SP) Start: 1/3/2002 Approved value: Finish: 28/2/2004 Company: R$ 972,700 FAPESP: R$ 320,000 Prumo is an original proposition which aims, Sum total: R$ 1,292,700 through a dynamic of innovative work, to obtain in- Start: 1/5/2003 cremental innovations in micro and small busines- Finish: 30/4/2005 ses (MSBs) in various sectors of the State of São Pau- lo economy and to create conditions for the Projects under the umbrella of the initials Prumo evolution of productive processes. From time to consist of mobile laboratory units (MUs) operated time, it may diagnose opportunities for radical inno- by specialized engineers and technicians who offer vations that bring about changes in the technologi- technological assistance on the premises of micro cal platform in the assisted sector. The project essen- and small businesses, remaining for between one and tially consists of a program of technological three days. By means of a battery of tests, analyses assistance at the company’s premises spread over one and examinations, deficiencies in raw materials, to three days provided by engineers and technicians equipment and processes are detected and the neces- by means of mobile laboratory units (MUs). The sary modifications indicated. In the current project, unit carries out tests, examinations and experi- the objective was to improve the performance in the ments, makes a diagnosis of problems and/or detects shoemaking sector in the State of São Paulo and con- possible failings and offers solutions. In the current

Translating Research into Business • 71 project, focused on the plastics transformation sec- Development of System of Control tor, it was also sought to identify specific technologi- 79 of Process of Crystallization in cal problems in that area, not capable of being solved Suspension Through Monitoring of by the MUs. The intention was to translate them into Concentration and Distribution a set of themes of common interest to a certain number of MSBs, to develop work proposals for Coordinator: them and identify possible support agencies for the Marcelo Martins Seckler financing of the projects drawn up. Institution: Polytechnic School/University of São Paulo (Poli/USP) Dedini Rapid Hydrolysis 78 (DHR Process) – Design, Company: Implementation and Operation of Rhodia Poliamida e Especialidade Ltda. Unit Development Process (UDP) Approved value: Company: R$ 149,400 Coordinator: FAPESP: R$ 136,105 Carlos Eduardo Vaz Rossell Sum total: R$ 285,505 Institution: Start: 1/6/2003 Technology Center of the State of São Paulo Finish: 30/11/2004 Cooperative of Sugar-cane, Sugar and Alcohol Producers producers (Copersucar) The present project aimed to develop a system Company: for the induction and control of the concentration Codistil S/A – Dedini and distribution of crystal sizes (DTC) in batch crystallization operations. The system is based on Approved value: measurement of the concentration of the solution Company: R$ 1,822,100 by refraction index for the monitoring of the super- FAPESP: R$ 1,751,487 saturation and on data from total count and nume- Sum total: R$ 3,573,587 rical distribution of the sizes of particle strings. This Start: 1/2/2002 data is obtained by the system of reflection of laser Finish: 30/6/2003 immersed in the suspension contained in the crystallizer (in-line measurement). This information The DHR process (Dedini Rapid Hydrolysis), provides the entry variables for a neural network which consists of the design, implementation and model adjusted to induce the volumetric DTC and operation of a development unit (UDP), brought the mass concentration of crystals in suspension. considerably lower costs for the production of alco- These variables constitute the base for the calcula- hol than those currently obtained in the best plants, tions of supersaturation in the crystallizer and for resulting in a significant socioeconomic contribu- the models based on populational balance. Based on tion for the country. The application of this process, the acquisition of reliable data susceptible to mode- considered by Copersucar to be a true breakthrough ling, it becomes possible to act on the manipulable in the sugar alcohol industry, enables the produc- variables by means of an adequate control strategy, tion of alcohol from bagasse, releasing the cane for seeking improvement in the quality of the product sugar production without increasing the planted and uniformity between batches. area, which brings considerable profitability to the plants. In this way, exports of sugar and alcohol can be increased, and competitive alcohol reduces the Prumo - Project of concern with the increase in the price of imported 80 Mobile Units for oil, leading to a positive impact on the external ba- Technological Assistance for lance of payments. The UDP has for the hydrolysis Micro and Small Businesses area for the recuperation of solvent, an area for in the Industrial Sector of treatment of hydrolyzed material, an area for fer- Rubber Transformation mentation and an area for the collection and treat- ment of the effluent. Coordinator: Selma Barbosa Jacomis / Armênio Gomes Pinto

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Institution: HUMAN SCIENCES Institute of Technological Research 81 of the State of São Paulo (IPT) Company: Primary Level Reading and Serviço Brasileiro de Apoio às Micro Writing Project for Members of e Pequenas Empresas – São Paulo (Sebrae–SP)) Staff at Cia. Nestlé de Alimentos Approved value: Coordinator: Company: R$ 946,220 Stela Conceição Bertholo Piconez FAPESP: R$ 170,000 / US$ 223,664.69 Sum total: R$ 1,116,220 / US$ 223,664.69 Institution: School of Education/ Start: 1/3/2002 University of São Paulo (USP) Finish: 28/2/2004 Company: Prumo is an original proposition which aims, Nestlé Industrial e Comercial Ltda. through a dynamic of innovative work, to obtain in- Approved value: cremental innovations in micro and small businesses Company total: R$ 104,412.48 (MSBs) in various sectors of the State of São Paulo FAPESP total: R$ 37,173 economy and to create conditions for the evolution of Sum total: R$ 141,585.48 productive processes. From time to time, it may diag- Start: 1/2/1996 nose opportunities for radical innovations that bring Finish: 31/3/1998 about changes in the technological platform in the as- sisted sector. The project essentially consists of a pro- A project directed towards the development of gram of technological assistance at the company’s ongoing research on the process of the teaching of premises spread over one to three days, provided by reading and basic schooling for adults with little or engineers and technicians by means of mobile labora- no schooling – in the specific case, among collabo- tory units (MUs). The unit carries out tests, examina- rators (staff from the Total Quality program) with tions and experiments, makes a diagnosis of problems Cia. Nestlé de Alimentos, at 17 industrial units loca- and/or detects possible failings and offers solutions. ted in four states: São Paulo, Rio de Janeiro, Minas In the current project it also identified technological Gerais and Bahia. Making use of the principles and problems in the rubber transformation sector not ca- resources of distance learning, both for training the pable of being solved by the MUs. The intention was teachers to teach adults to read and write, as well as to translate them into a set of themes of common in- in attending to the primary school education, the terest to a certain number of MSBs, to develop work aim was to provide an opportunity for consolida- proposals for them and identify possible support ting a partnership between university and company agencies for the financing of the projects drawn up. in the sector.

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1st BIDDING INSTRUCTIONS Approved value: Phase 1: R$ 44,360 Phase 2: R$ 182,813 Human Growth Hormone 1 Production using The research group of the Bioengineering De- Recombinant DNA Technology partment of the Institute of Energy and Nuclear Research/National Nuclear Energy Comission (Ipen/ Coordinator: CNEN/SP) has been working on the production and Jaime Francisco Leyton Ritter characterization of human pituitary hormones in general and of the human growth hormone in parti- Company: cular. Since 1994, this laboratory has had an agree- Genosis Biotecnológica Ltda. ment with the company Hormogen Biotecnologia Approved value: Imp. Exp. Ltda. Hormogen’s main purpose is the Phase 1: R$ 19,300 / US$ 27,538 production and sale of hGH obtained through re- Phase 2: R$ 46,838 / US$ 74,200 combinant DNA techniques in transformed bacte- ria. The product’s high social potential has already The use of pharmaceutical products produced by been shown, and it is indispensable in the treatment recombinant DNS technology has become a reality of various forms of dwarfism and recommended in in today’s world. Brazil, however, has no pharmaceu- serious conditions of debility. Its use in cases of os- tical laboratory producing pharmaceutical products teoporosis, bone fractures, burns, and kidney defici- using this technology. This project intends to create ency is being studied and is partly being carried out a company able to produce pharmaceutical formula- as are its effect on rejuvenation and on the increase tions using this method. The choice of the Human of muscle mass. This hormone, as is the case with Growth Hormone (hGH) as the first product, in ad- practically all pharmaceutical products obtained dition to its therapeutic importance, is due to the through genetic engineering techniques, is not yet fact that most of the research has already been com- produced in Brazil. This research is intended to bu- pleted – from isolating the gene and its expression in ild significant vectors enabling an industrial increa- bacterium to the purification of the recombinant, se in the bacterial periplasmic secretion of the pro- biologically active product on a laboratory scale. The duct, optimizing the fermentation process in the result of this project, recombinant human growth bioreactor, increasing at the same time the biomass hormone (rHGH), is an indispensable product for and the production of hGH by bacteria, and impro- promoting growth in cases of dwarfism caused by a vements to the purification stages. deficiency of hGH. Other therapeutic uses for this product (aging, osteoporosis, recovery from fractu- res, loss of muscular mass in AIDS) are being resear- Use of Computer Learning ched. All the hGH currently used in Brazil is impor- 3 and OCR Mathematical ted and there is a shortage in the market. It is Morphology in the Computer Stage intended to scale up the fermentation process to in- dustrial scale, partially to scale up the purification Coordinator: process carrying out the appropriate purity tests and Felício Hissaaki Sakamoto performing clinical tests. Company: Carta Consultoria Ltda. Optimization of the Yields from Approved value: 2 Bacterial Expression, and the Phase 1: R$ 24,000 Fermentation and Purification of Phase 2: R$ 51,000 Recombinant Human Growth Hormone in order to Enable its The object of this project is to develop a study to Production and Sale enable the development of the use of automatic op- tical character recognition (OCR) in faxes sent by Coordinator: computer. Based on this recognition, the application Paolo Bartolini must enable structured storage of information recei- Company: ved and the carrying out of swift searches and reco- Hormogen Biotecnologia Imp. Exp. Ltda. veries of this information. The theory used will be

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based on Mathematical Morphology. This theory is Development of useful for modeling changes between images and, 5 Refrigerators for this reason, it has been used quite successfully to Based on Thermo-acoustics solve various image processing problems. By auto- Phenomenon mating the morphological operators project (map- ping between images), based on computer learning, Coordinator: it is intended to show the feasibility of developing a Humberto Pontes Cardoso program able to be used automatically in offices wi- Company: thout users having to have specific knowledge of the Equatorial Sistemas Ltda. technique used. The expected benefits are quite bro- ad, particularly in space saving in storing informati- Approved value: on, in enabling automatic classification of, and ac- Phase 1: R$ 66,635 cess to, fax contents, and in searching for subjects Phase 2: R$ 193,500 and specific words, something which was previously impossible with matrix (bitmap) images. The recent progress in developing long-wave photovoltaic detectors for imagers installed in artifi- cial satellites has created an increasing demand for Improvement of the Vacuum highly reliable, low-weight and low energy consu- 4 Press Filter for the Sugar ming cryogenic refrigeration systems. Micro-cryoge- and Alcohol Industry nic, thermo-acoustic refrigerators are being develo- ped by the world’s main space research centers as an Coordinator: alternative to the passive refrigeration systems (cryo- Pedro Gustavo Córdoba Junior genic radiators) and thermoelectric refrigerators. Company: Recent progress in microelectronics, especially in Technopulp Consultoria e Com. , also requires highly reliable, low- de Equipamentos Industriais Ltda. weight micro refrigerators. Thermo-acoustic micro refrigerators consist of a stainless steel tube contai- Approved value: ning a mixture of gases (normally helium and xe- Phase 1: R$ 50,000 non), a loud-speaker installed at one end and a ther- Phase 2: R$ 197,400 mo-acoustic dephaser (TAD) positioned inside the tube at the opposite end. In triggering the loudspea- The purpose of this piece of research is the tech- ker, compression and decompression waves are pro- nological improvement of the continuous double duced in the gas that give rise to successive heat ex- screen filter known as a Vacuum Press, used in pu- changes between the various layers of TAD and the rifying the mixed fresh sugarcane juice (garapa) in gas in such a way that, in the end, a quantity of heat sugar and alcohol mills, enabling an increase in effi- is removed from the TAD that is greater than the one ciency and productivity. The project aims to study produced. This technology, as well as being very pro- the market in greater detail, with laboratory rese- mising for use in space and in the local cooling of arch testing new membranes and filter coadjutants, microcircuits, also seems to be an alternative for do- such as polymers and chemical coagulation agents, mestic refrigerators. to achieve better operating performance. This is only possible through work in the laboratory and at the mill, using a pilot filter for testing. Setting up a A Computer laboratory with pilot equipment will enable the 6 System for Analyzing team to achieve higher levels of automation and ef- Injuries to the Skin ficiency, enabling the company to broaden the ran- ge offered to the market, leading to social and eco- Coordinator: nomic benefits by creating new jobs. The vacuum Antônio Francisco Junior press filter is the company’s most recent develop- ment in the field of engineering and processes asso- Company: ciated with the sugar and alcohol, and paper and Atonus Engenharia de Sistemas Ltda. pulp sectors, to produce satisfactory results, repla- Approved value: cing conventional rotary filters, that are not very ef- Phase 1: R$12,090 ficient at retaining suspended particulate matter Phase 2: R$ 97,074 and have a high rate of loss of sucrose. Grants: R$ 126,047.80

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Brazil, with its people constantly exposed to sun the construction of the manta is of the multimode rays, has witnessed increasing rises in the number of step index type, with a PMMA nucleus and a Teflon skin lesions. In order to help healthcare specialists to skin. The present proposal uses commercially availa- diagnose skin lesions, especially skin cancer, Atonus ble optical fiber, and the technological innovation Engenharia de Sistemas Ltda. proposes developing a lies in the use of a mechanical process to alter the to- computer system for capturing, storing and analy- tal internal reflection and producing controlled late- zing images of human skin. With the local help of ral light emission. The fibers will emit light through this system and remote transfer over the Internet of the skin inside the blanket. In the project’s first digital images obtained by specialists in the medical phase, mechanical devices and tools were built that field, it is intended to reduce the degree of subjecti- produce controlled corrugations on the surface of vity in examining skin lesions. Thus, the present pro- the fibers and tests were carried out on fibers of dif- ject aims not only to develop equipment, but also to ferent diameters and of different materials. In the se- publicize and institutionalize the approach to health cond phase, the product itself was developed, which problems through the remote exchange of texts and is in the final phases of testing. images, known as telemedicine. The first phase to be approached has to do with adequate lighting of the Development of General human epidermis, followed by capturing the digital 8 Purpose, Low-cost, images. To do this,Atonus is developing an optical fi- Controller operated by a ber video-dermatoscope, using Brazilian technology, Microprocessor with the Capacity in order to light the human epidermis uniformly. Af- for Remote Data Communication ter the digital image of the epidermis has been captu- in Multipoint Networks red, specific software will be used for morphological and radiometric analysis of the skin lesions, especi- Coordinator: ally with regard to the diagnosis of skin cancer. Durval Makoto Akamatu Company: Incon Eletrônica Ltda. Project and Development 7 of Equipment for Neonatal Approved value: Phototherapy Based on Phase 1: R$ 70,847.60 Corrugated Optical Fiber Phase 2: R$ 233,948

Coordinator: The purpose of this work is the design and cons- Cícero Lívio Omegna de Souza Filho truction of prototypes of low-cost, general purpose, microprocessor-operated controllers with the capa- Company: city for communicating remote data in multipoint Kom Montagens e Comércio Ltda. networks, in order to define the internal elements of Approved value: a product of this sort. This product will be chosen Phase 1: R$ 21,000 / US$ 26,796 from among the prototypes and will be used initially Phase 2: R$ 101,500 / US$ 98,500 as a controller of certain physical elements, such as Grants: R$ 46,709.40 temperature, pressure, and air humidity in refrigera- tion systems for machine operating panels, cold Physiological jaundice is the most commonly room systems and air conditioners for telecommu- found problem in the neonatal period, affecting 30 nications system containers. The requirements of to 50 per cent of new-born babies. Around 10 per the product to be developed include having a low- cent of these children need phototherapeutic treat- cost controller using a micro-controller, peripherals ment, by present-day standards. The light-emitting and a modem chip assembled on an SMD board. devices used for this treatment can be essentially of The data communication function over a telephone three types: using a fluorescent bulb, a halogen bulb line is carried out by the modem chip, giving the mounted on a spot type reflector, and a cold light controller a competitive advantage over other pro- emitting manta using optical fiber. The proposed ducts on the market. As a result of this phase of the phototherapeutic device uses modified optical fiber development of the controller, a prototype will be consisting of a light radiating blanket that will be in built and tested to assess the definitive specifications contact with new-born child experiencing a high de- in the project, to suggest adjustments and to give a gree of bilirubinaemia. The light guide to be used in more accurate view of the costs involved.

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20-Meter Range Laser Unisoma developed and introduced the PIPA sys- 9 Distance Meter for Industrial Use tem in Sadia, from 1989 to 1997: PIPA is the Portu- guese acronym for Integrated Poultry Production Coordinator: Planning. This system is made up of various modu- Mario Antonio Stefani les based on mathematical and statistical techniques, aimed at optimally concatenating the decision-taking Company: processes through the entire integrated chicken pro- Opto Eletrônica S/A duction chain, ranging from the production of one- Approved value: day-old chicks to the consumer market. One of the Phase 1: R$ 6,000 / US$ 40,742 critical points in this production chain is the daily Phase 2: R$ 111,362 / US$ 75,117 production control in the slaughterhouses. Classifi- cation of the products by weight requires dynamic The purpose of this project is to develop laser weighing procedures. Unisoma is developing a weig- distance meters with a range of from 0.5 to 20 me- hing system using computer viewing techniques, as- ters. There are various ways of measuring distance sociating the images of the chicken carcasses with with lasers. The most common is the geometric me- their respective weights. This system enables produc- thod also known as the laser triangulation method. tion flows to be programmed better, since weighing Nonetheless, when a high degree of accuracy is re- takes place immediately before chilling the carcasses, quired, this method is only useful for short distan- about an hour before these carcasses go to the reweig- ces, from 2 mm to 500 mm. The desired range is jus- hing and classification point, thus enabling better tified by the countless potential uses – civil production flow. This project aims to complete the engineering, measurement in grain silos, the level of development of a prototype to be installed at Sadia’s liquids, detection and positioning of loads in freight Toledo (PR) plant. cars, security systems, etc. For it to be feasible to use, however, the equipment must be low-cost and por- table. Because of the limitations of the triangulation Development of a 16xE1 method for longer distances, new methods are nee- 11 Multiplexer/Optical Modem ded to make the system feasible and practical. The with Technological Innovation most common is the telemetry method of short bursts of laser light, and this requires a careful elec- Coordinator: tronic design project. The second method consists of Rege Romeu Scarabucci comparing the phase of a modulated waveband of Company: the laser beam with the returning signal. Opto Ele- Asga Microeletrônica S/A trônica S/A has already carried out the conceptual phase of developing this project. Based on this study Approved value: a set of requirements was prepared, specifying the Phase 1: R$ 20,000 / US$ 26,000 main features the product must have: measurement Phase 2: R$ 53,510 / US$ 127,060 range of up 20m, accuracy of better than 1 cm, res- ponse time of no more than 1 second, visible laser of The development of the 16xE1 Multiplexer/ Opti- up to 5 MW of average power. The equipment must cal Modem (MMO 16xE1) will take place in two pha- also be portable and be able to work in sunlight. ses. In phase 1, three studies of innovations to be in- cluded in the MMO 16xE1 will be carried out. In phase 2, these and other technological innovations Daily Production Control at a will be implemented in the equipment, the design and 10 Chicken Slaughterhouse production of prototypes, in which they will be the main focus. The MMO 16xE1 is being developed for Coordinator: use in the Primary Optical Route (POR) defined by Miguel Taube Netto the Telebrás System. It must, however, meet the speci- fications of Technical Standard no. 225-540-786 of Company: December 1996, Functional Requirements and Equip- Unisoma Matemática para Produtividade Ltda. ment Performance for the Primary Optical Network. Approved value: The MMO 16xE1 will perform the multiplexing and Phase 1: R$ 49,700 demultiplexing of up to 16 E1 tributary channels at a Phase 2: R$ 120,760 speed of 2,048 kb/s, as well as carrying out the conver-

Translating Research into Business • 79 sions of added signals from electrical to optical and The purpose of this research is to develop a pro- vice-versa, enabling communication between the tri- duction process for ultra-pure manganese carbona- butary channels by a pair of optical fibers. The main te for use in magnetic ceramics. Two courses of acti- technological innovations to be introduced into the on will be assessed. The first is through leaching MMO 16xE1 are: 1) measurements of Operational manganese monoxide with an ammonium carbona- Performance – Measurement of Optical Transmitting te solution. The manganese is mixed as an anion and Power – Measurement of Optical Reception Power – made soluble, when the ammonium content is abo- Measurement of the Optical Interleaving Error Rate; ve a given level. Lowering the ammonia content, the 2) the Introduction of Radial and Ring Structures; 3) manganese is precipitated as a very pure carbonate. managing Failures and the Performance of Optical The process developed by Dr. R. S. Dean of the U.S. Interlacing. In particular, an FPGA chip will be deve- Bureau of Mines, sought, in its original form, to take loped to measure the error rate with a BIP (Bit Inter- advantage of low-content, American manganese ore leaved Parity) code. for use in steelmaking. Although very pure, the car- bonate this process produces still does not attain the levels that are desirable for use in electronics. Preli- Development of VDS Sheets minary studies have shown that the introduction of 12 (Vibration Damping Steel) for supplementary purification stages has a high proba- Absorbing Noise and Vibration bility of achieving a purer form of carbonate. The second course of action for the process aims to im- Coordinator: prove the classic method of producing manganese Francisco de Paula Assis Junior carbonate based on a reaction of manganese sulfate in solution with ammonium carbonate. Using this Company: method, it is intended to purify the manganese sul- Fitafer Indústria e Comércio Ltda. fate solution through adsorption and crystallization. Approved value: Phase 1: R$ 48,200 Phase 2: R$ 198,500 Research and Development 14 into Micro-controlled Systems for This project can be summed up as the develop- Monitoring the Milling of ment of a process for laminating two or more sheets Components Using Acoustic Emission together, of the same or different thickness, with the interspacing of plastic polymers or other materials Coordinator: adhering to the internal surfaces, also known as – Vi- Luiz André Melara de Campos Bicudo bration Damping Steel (VDS) –, to reduce noise and Company: vibration induced in these sheets at various frequency Sensis São Carlos Ind. e Com. ranges. This is the development of a new process and Equipamentos Eletrônicos Ltda. – ME a new product as yet unprecedented in Brazil, which will enable the sound insulation of equipment such as Approved value: motor vehicles, household appliances, and machinery Phase 1: R$ 65,405 / US$ 1,795 in general, or sound insulation between different spa- Phase 2: R$ 70,100 / US$ 27,434 ces as in the case of room dividers. This research project intends to define the neces- Production of Ultra-Pure sary characteristics for developing a digital monito- 13 Manganese Carbonate ring system. The equipment must monitor and pro- cess the acoustic signals produced by the system and Coordinator: communicate with the control of machine-tools Silvio Benedicto Alvarinho in order to correct problems or improve working conditions. The research intends to establish preci- Company: sely the most appropriate methods of handling the Fermavi Indústria e Comércio acoustic signals and monitoring strategies for indus- de Produtos Químicos Ltda. trial use. The development of a hybrid filtering sys- Approved value: tem will also be developed, as well as frequency Phase 1: R$ 13,300 analysis software. Sensis was founded in May 1995 by Phase 2: R$ 170,850 / US$ 24,215 postgraduate students and former students of the

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São Carlos Engineering School, who carried out rese- Advanced Materials for the arch into the monitoring and automation of the pro- 16 Manufacturing of Bipolar Separators cess of rectification. Sensis developed a first product, for Ion Conducting Polymer Fuels Cells called BM12, which is an acoustic emissions monitor using similar technology. In using and monitoring Coordinator: the BM12, Sensis observed the need to develop a new Antonio César Ferreira digital technology system, aimed at increasing the re- Company: liability and quality of precision manufacturing ope- Unitech rations as well as lowering their costs. The digital sys- tem will enable the system to interact more with the Approved value: machine and make it easier to install. Phase 1: R$ 14,342 / US$ 10,182 Phase 2: R$ 83,145 / US$ 67,300

Development and The project’s object is to develop bipolar separa- 15 Assessment of tors using carbon fibers for ion conducting polymer Pseudo-chelates in Bleaching fuels cells and phosphoric acid. Fuel cells are ther- Pulp Paste with H2O2 modynamically efficient energy converters and do and in Inhibiting not cause pollution. The material traditionally used Equipment Corrosion has been a special type of graphite specifically for use in fuel cells. With the technological progress in fuel Coordinator: cell components, such as ion conducting electrodes Paulo Rogério Pinto Rodrigues/Hugo Antônio Vil- and polymers, however, the graphite separators have ca Melendez come to be one of the main bottlenecks in building cell prototypes. To achieve high power density, more Company: compact cell prototypes need to be built, but the re- Logos Química Ltda. duction in the thickness of the graphite makes them Approved value: very fragile. This project is designed to find a new Phase 1: R$ 45,872 concept for manufacturing bipolar separators using Phase 2: R$ 112,879.80 / US$ 85,940.80 carbon fiber. In the first stage we will use two produc- tion processes. In one of them, the separators will be New pulp bleaching processes, considered clean manufactured from a mixture of carbon fiber, phe- technologies meeting the requirements of environ- nolic resin, and carbon powder deriving from oil, with mental legislation, use hydrogen peroxide as an oxi- subsequent high-temperature sintering to convert dizing agent. Nonetheless, they require pre-blea- the resin into graphite. In the other process, the bipo- ching of the pulp, using chelates, to remove the lar separators will be manufactured on the basis of transitional metallic ions, such as iron, copper and mixtures of carbon fiber, polymers, and carbon pow- manganese, which act as stabilizers, preventing the der, with subsequent hot rolling to form sheets. In fiber from breaking down (attack on the polysac- phase 2, a 2 kW-prototype will be built using the new charides) in the subsequent treatment with peroxi- concept of the separators developed in this project. de. This research project intends to develop a new product to be called “pseudo-chelates”,which differs from the traditional chelate DTPA: (Diethylenetria- Development of Technology mine pentaacetic acid) and which it is intended to 17 for Assessing Environmental Risk in introduce in the Brazilian market. The study propo- Places with Contaminated ses to assess the influence of these pseudo-chelates Underground Soil and Aquifers on the efficiency of the bleaching process (increase of whiteness) and the consequent saving of peroxi- Coordinator: de. The inhibiting action of these compounds on Nelson Ellert the corrosion of the metals used in the “pre-treat- Company: ment of the pulp”,bleaching and subsequent stages, Hidro Ambiente Projetos, will also be assessed. Consultoria e Serviços S/C Ltda.

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Approved value: plete integration of the system embarked upon will Phase 1: R$ 45,200 enable better operational performance (through gre- Phase 2: R$ 150,750 / US$ 29,750 ater resident processing capacity) and a lower instal- lation costs. The use of alternative satellite communi- This research project is intended to consolidate cations and the use of dispersed control centers will solutions for the restoration of the official city of enable operating costs to be lowered compared with Cubatão (SP) garbage dump. To achieve these ob- the solutions currently available on the market. The jectives it is intended to develop and apply methods system will enable greater operational security and of risk assessment appropriate to tropical environ- planning, as well as the automatic location of vehicles. mental conditions. Risk Assessment methods are The main users will be commercial vehicle fleets, mi- currently quite frequently applied in northern he- litary vehicles, ambulances and private vehicles. misphere countries, as a decision-making tool in al- locating priorities to the environmental restoration of contaminated areas. These methods will enable Development of more efficient underground soil and aquifer reme- 19 a System for Measuring the diation technologies to be identified, having less im- Concentration of Pollutants in pact from the social and environmental point of the Atmosphere with Infrared view. This garbage dump, located along the valleys Lasers (CO2 and CO) using of the River Cubatão and of the dos Pilões creek, at Photo-acoustic Spectroscopes the foot of the Serra do Mar ridge, was used up to the 70s as a dump for household waste. The lack of Coordinator: control enabled dangerous, and sometimes toxic in- Edjar Martins Telles dustrial waste mixed with household and hospital Company: waste to be deposited. After having been officially Unilaser Indústria e Comércio Ltda. deactivated, around 70 families moved there. The presence of dangerous and toxic waste contamina- Approved value: ted some of the families living there. As a result of Phase 1: R$ 61,005 this episode the families were obliged to leave the Phase 2: R$ 181,500 area. Downstream from the area, there is a water re- servoir belonging to Sabesp. The area is still used for The purpose of this project is to develop a devi- recreation. The presence of heavy metals, volatile ce able to measure on-the-spot concentrations of va- organic compounds and pesticides was detected in rious molecular types (pollutants) present in the at- the groundwater and soil in concentrations above mosphere with a detection limit of 1 ppb (10-9) or the permitted levels. less. This device will use an infrared laser to stimula- te the molecules of interest and the detection of the radiation absorbed is done using the photo-acoustic Automatic System for effect. Atmospheric pollution by motor vehicles, fac- 18 Monitoring Vehicle Routes tories, slash and burn agriculture, and other sources produces undesirable consequences both for human Coordinator: health and for the environment. The first step in es- Ailton de Assis Queiroga tablishing the size of the problem (and its solution) is to determine accurately the concentrations of the Company: different pollutants in the air, as well as their distri- Compsis Computadores e bution over space and time. To do this, a CO laser Sistemas Indústria e Comércio Ltda. 2 will be used initially to develop the spectrometer. A Approved value: CO laser is of great interest insofar as it can be used Phase 1: R$ 44,193.80 to detect various pollutants arising from the com- Phase 2: R$ 153,100 bustion of gasoline and diesel oil. The objectives of phase 1 are: a project for a photo-acoustic spectro- The purpose of this research project is to imple- meter for gases using a CO2 laser; constructing a ment an automatic monitoring system for vehicle photo-acoustic cell for gases to take preliminary me- routes, integrating GPS receiving modules, processing asurements for the test; construction of a CO2 laser and modem communication with mobile phones, operating at 80 lines, between 9 and 11 meters, with VHF/UHF, and communication satellites. The com- power output of 5-10 W. In phase 2, they are: the

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construction of a photo-acoustic spectrometer for Enscer – Computerized and Integrated gases using a CO2 laser; the development of softwa- 21 re to analyze samples, and the development of a CO System for Teaching and laser and a market survey. Assessing Learning and Neural Progress in Mentally Deficient Children Equipment for 20 Predicting Fungal Coordinator: Diseases in Vegetables Armando Freitas da Rocha Company: Coordinator: Eina– Estudos em Inteligência Nilson Augusto Villa Nova Natural e Artificial Company: Approved value: Microdesign Informática Phase 1: R$ 45,000 Tecnologia Indústria e Comércio Ltda. Phase 2: R$ 131,992 Approved value: Phase 1: R$ 4,293 This research project is intended to develop a Phase 2: R$ 70,938 / US$ 5,584.20 computerized system for the quantitative analysis of electroencephalograms (EEG), to help in processing The purpose of this project is to develop equip- and standardizing the medical diagnosis of disabled ment for forecasting diseases caused by fungi in ve- brains and supplying a set of educational games for getables, providing farmers with a technical referen- supplementing the process of teaching handicapped ce for the use of fungicides and, for scientists, an children. Countless causes contribute to the cerebral instrument for improving the algorithms that will injuries that characterize the brains of handicapped form part of the project. The planned equipment children and, in general, more than one neural sys- will be made up of hardware that collects, records tem (visual, motor, auditory, etc.) is affected in each and processes agro-meteorological data in the area of these children. This complicates matters in educa- of monitored planting and informs, through a dis- ting them. Quantitative analysis of the EEG has pro- play (or also through an optical interface), as to the ved efficient in characterizing specific functional de- possibility of fungus infestation and its severity. In ficits and provides reasonable spatial differentiation recent decades, the advent of new technologies has to justify its use as an important diagnostic tool. Au- meant that agriculture has changed a great deal. tomated quantitative electroencephalographs are fe- Maximization of productivity has been achieved asible nowadays thanks to the use of computers. So- mostly by using pesticides. These have caused con- called artificial intelligence is the information cern as to their impact on the environment, their in- technology field that seeks to simulate the intelligent creased cost, and the exodus of people from the processes undertaken by the brain, but computers countryside. The equipment in question must be have also been used as an auxiliary tool in various low-cost, be able to withstand harsh environmental educational processes. For these reasons, it is propo- usage conditions and be easy to use and set up. The sed here to develop the Enscer system as a compute- system will be assembled with degree of protection rized system for quantitative analysis of the EEG appropriate for the environment it will be used in made up of the following modules: database; online and it must be independently battery- and solar- acquisition module and offline intelligent diagnosis cell- operated. Studies conducted abroad, where the and prognosis module and the educational games method of predicting diseases has been employed module for developing concepts and teaching chil- based on agro-meteorological data show a dramatic dren to read and write. There is an agreement with reduction in the use of fungicides to control and the Apae (Association of Parents and Friends of the contain the diseases. Mentally Handicapped) in Jundiaí.

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Technological Development of Approved value: 22 Micro-environmental Systems for the Phase 1: R$ 23,960 / US$ 781 Rearing, Maintenance and Phase 2: R$ 24,741 / US$ 90,000 Experimentation of Small Animals in Breeding Units The purpose of this piece of research is to deve- lop and build a spectrophotometric workstation Coordinator: made up of a spectrophotometer coupled to a Habib Guy Marie Nahas three-axis robot for accessing 24 reagents and ano- ther also of three axes for choosing one hundred Company: samples, both of them randomly and easily pro- Hvac Engenharia e Comércio Ltda. grammable, managed by a standard IBM-compati- Approved value: ble PC. Multi-element detection, each using on Phase 1: R$ 49,250 average three reagents and random access both for Phase 2: R$ 200,000 the samples and the reagents, are targets to be achieved. The purpose is also to train and qualify The purpose of the project is to study the techni- new technicians and engineering students to be ta- cal and financial feasibility of producing specific ken on in the future by the company. The modern equipment for laboratories of experimental animals chemical industry seeks to automate laboratories, in this country, with a view to introducing them. To robotics, optimization, simplification, chemo-me- do this, it is expected to undertake two basic engine- tric signal processing, easy management results and ering projects, one of them using conventional tech- low cost. From the standpoint of automation, the nology and the other based on this technological in- FIA (Flow Injection Analysis) analysis systems are novation. The progress of biomedical research has appropriate when it is wished to conduct an analy- demanded ever more sophisticated animal models sis, or several analyses, involving a large number of in relation to sanitary control. Obtaining animals sa- samples per batch. In industrial chemical laborato- nitarily compatible with the best international stan- ries in general, however, there is the need to exami- dards has required considerable spending on the ne various analyses involving a small number of animal houses, particularly as regards the buildings samples. These samples must be examined imme- and equipment. One of the most significant points is diately. They also require random access and versa- the control of the atmosphere of the animal houses, tility which is not available in current flow systems including the control of the temperature and the re- but which are already present in biochemical auto- lative humidity, as well as the proper removal of pol- mation systems. lutants, such as ammonia, from the animals’ envi- ronment. The technology currently employed on this control uses expensive systems and equipment Instrumental Evaluation of doubtful efficiency, since most of the time, they 24 of the Quality of Pork and consist of adaptations of systems or equipment stan- its Uses in the Meat Industry dardized for use in establishing human comfort le- vels. Experiments are underway intended to esta- Coordinator: blish specific equipment for animal houses. The Expedito Tadeu Facco Silveira preliminary results suggest encouraging results from the standpoint of sanitary standards for the animals, Company: with the possibility of lowering both investment and Didai Tecnologia Ltda. maintenance costs. Approved value: Phase 1: R$ 30,805

Spectrophotometric The quality of pork can be affected by the PSE 23 Workstation (pale, soft, exudative meat) or the DFD (dark and firm meat, dry on the surface) conditions. The pre- Coordinator: sence of these anomalies affects the functional pro- Lídio Kazuo Takayama perties of the muscle intended for processing, as well Company: as the appearance of the final product. Until the Femto Indústria e Comércio de Instrumentos Ltda. PSE/DFD conditions in pigs are eliminated through

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genetic selection, pre-slaughter handling, and the will control its operation. After the examination, the use of good slaughtering methods, there will be an software will perform a statistical pre-diagnosis, com- ongoing need to detect, under commercial conditi- paring the results of the examination with data pre- ons, the incidence of PSE/DFD in order to use this recorded in memory. It is also intended to use the type of meat properly and help minimize losses in equipment remotely, through the internet – patients, the industry. The present research aims to develop at home, will conduct their own examinations; the an information technology program to be coupled doctor will receive the report in his or her office, over to the optical system of characterizing pig carcasses. the telephone line, and will then be able to offer gui- In the first stage, 12,000 animals will take part in the dance to the patient. In future versions, it is intended census of the number of pigs slaughtered in four to include a wireless modem (pager type), to be used slaughterhouses in the state of São Paulo. Data on with a cardiac monitor in clinics and hospital ICUs. the thickness of the bacon and the weight of the car- cass will be gathered and 120 carcasses will be dissec- ted to arrive at an equation that will provide the pro- Bragg Grid Characterizers portion of lean meat representative of the pigs 26 in Optical Fiber slaughtered in each commercial establishment. The information obtained will also help to develop a Coordinator: swift method of assessing the ability to retain water, Sérgio Barcelos intramuscular fat and total pigmentation, and this Company: will be incorporated into the system. FiberWork – Optical Communications Approved value: Electrocardiograph Linked Phase 1: R$ 2,620 / US$ 41,200 25 to a PC with an End Cost Phase 2: R$ 31,000 / US$ 79,650 of between R$ 500 and R$ 1,000 The purpose of this research is to develop a com- Coordinator: mercial prototype of a high-resolution instrument Climério dos Santos Vieira for characterizing optical fiber devices. It provides measurements of phase dispersal and the delay time Company: in narrow- and broadband optical elements, with Elemed Equipamentos particular interest for Bragg grids in optical fibers. Médico-Hospitalares Ltda. – ME The equipment is based on an original interferome- Approved value: tric technique, insensitive to polarization, and uses Phase 1: R$ 27,240 an adjustable, high-resolution, wavelength laser, to- gether with a fully automated system for capturing It is intended to study the feasibility of building a data. It is able to measure delay time and dispersal low-cost electrocardiograph to operate coupled to a with accuracy greater than 0.5 ps and 1 ps/nm, res- PC. The equipment will use the potential of a PC, pectively, and with a wavelength resolution of bet- with the expensive and bulky components of a com- ter than 1 nm. There is no commercially available mon electrocardiograph (signal monitor and plotter equipment that can take these measurements. Its output) being replaced by the PC’s screen and printer. closest competitor is laboratory-assembled and ba- Thus, the intention is to simplify as far as possible the sed on the method of shifting the RF signal phase, electrocardiograph hardware, keeping its cost to a mi- which however, costs a great deal to set up and pro- nimum. The PC will run on Windows, with a window vides less accuracy than the proposed equipment. It for the operation. A version will also be produced to is expected that there will be an enormous market run under DOS. This electrocardiograph will work potential, because of the growing importance of together with patient registration software, keeping Bragg grids in fiber optics. the result of the examination in the PC itself, along with the patient’s record. The equipment will be made up of box with a liquid crystal or a LED display for Diamond monitoring its functioning, with the electrodes for 27 Sanders connecting to the patient and a power cable with a 127/220 A/C plug and mobile-phone type battery, Coordinator: and another cable for connecting to the PC, which Benjamin Grossman

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Company: Manufacture of Cast Cromática Sistemas de Comunicação 29 Quartz Products de Dados e Informática Ltda. Coordinator: Approved value: Yoshikazo Ernesto Nagai Phase 1: R$ 40,000 Company: This is a project to develop or adapt machinery Optron Micromecânica Óptica Ltda. – ME for the manufacture of diamond sanders. The proce- Approved value: dure chosen was that of adapting a flexography prin- Phase 1: R$ 20,743.20 ting machine used in the manufacture of plastic la- bels for use in liquids containing suspended, abrasive Cast quartz, because of its thermal, optical, and me- particles in a plastic substrate. Variables to be con- chanical properties and its resistance to chemical erosi- trolled include the thickness of the layer to be depo- on, is used in various scientific and technological appli- sited, the adherence of the deposit, the proportions in cations, sometimes as a plain structural element in the the makeup of the liquid suspended with abrasives, high-temperature transparent tube, sometimes as the the speed of drawing the coil so as to enable proper main element in high-performance, telecommunicati- drying of the deposit, and in particular, the choice of ons optical fiber. Mastery of its processing based on the the suspended liquid and the quality of the diamond ore is an important target in any scientific and techno- powder, seen through characteristics such as the his- logical policy. This research plan seeks to extend the ex- togram of the narrow overflow, and the repetition of periment of fusing quartz from the academic labora- the characteristics in various batches, etc. tory to the production sector, initially at craftsmen level with production limited by the size of the Brazilian consumer market, which consists of government and a Development of the few private research centers. In this initial stage it is in- 28 Technology of Molding of tended to transform the Brazilian mined quartz into Ceramic Items by Injection samples of structural elements and some laboratory objects. To do this, the main item of research equip- Coordinator: ment, a flame oven of the Verneuil type already manu- Siegfried Eugen Rayer factured by the company, will undergo modification ai- Company: med at increasing the area of deposit to produce larger Rayplast Indústria e Comércio Ltda. dowels. The feasibility of producing cast quartz tubes using the same oven will also be researched. Approved value: Phase 1: R$ 34,180 Research and Technological The purpose of this project is to develop injecti- 30 Development into the in vitro on technology for ceramic items in this country. The Transfer of Embryos, and use of ceramic techniques is limited, very often, by their Sexing and Fertilization inherent difficulties in the traditional processes of molding, by the cost of achieving the size tolerances Coordinator: required and the production of complex geometric Jorge Nicolau Neto molds. The process of adaptation of the ceramics by means of injection reduces these limitations subs- Company: tantially, making it possible to use ceramic compo- Embrionic nents in complex shapes, with narrow size tolerances Approved value: and delicate surface finishing at a cost acceptable to Phase 1: R$ 50,000 the consumer market. In Brazil, this technique of molding ceramics is not used because nobody has The objective of this project is to implement, in mastered the technology. All the ceramic compo- this country, two techniques of transferring embryos nents with these features are imported. already employed abroad: Embryo Sexing and In Vi-

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tro Fertilization. The first enables the sex of the embr- low levels of exposure. In the present work Toxikón yo to be identified immediately after being collected will seek to develop analytical methodology for de- from the uterus of the donor. This opens up immen- termining the trans-trans mucoid acid (t-t-MA) and se zootechnical possibilities, since, economically, it is the urinary phenyl mercaptan acid (S-PMA). rarely worthwhile to raise pedigree males. The bree- der, therefore, opts for the insemination or freezing of female embryos. The technique most used around the 2nd BIDDING INSTRUCTIONS world consists of puncturing (by micro-manipulati- on) the seven-day-old embryo, withdrawing a frag- ment whose DNA code will reveal the sex of the Assisted Cutting of embryo in the laboratory in around an hour (by elec- 32 Digital Images and Videos trophoresis). The second technique, besides signifi- cantly multiplying the female, enables the multiplica- Coordinator: tion of the semen itself, since the eggs collected will be Robert Liang Koo fertilized. With the revolution in genetic engineering, Company: embryo transfer has become universally established SDC Engenharia, Sistemas, since it represents a technique which enables rapid ex- Eletrônica, Imp. e Exp. Ltda. pansion and greater productivity in cattle herds. Approved value: Phase 1: R$ 35,000 Biological Markers Phase 2: R$ 57,000 / US$ 35,000 31 of Occupational Exposure to Benzene The SDC Company has been developing, through the project Softex, a "tool box" of mathema- Coordinator: tical morphology for the software of the visual pro- Henrique Vicente Della Rosa gram Matlab. Mathematical morphology is a non-li- near technique for handling digital images for image Company: segmentation. This proposal intends to develop cut- Toxikón Assessoria Toxicológica S/C Ltda. ting tools of the type that can easily be transferred Approved value: for use in the different programs already in use on Phase 1: R$ 32,820 the market, such as Photoshop, Matlab itself, 3DStu- dio, etc. The manipulation of a photograph and of a This project, intended to meet the needs of pre- video demands various sophisticated techniques of ventative techniques not yet applied in Brazil, is a pri- image processing. The growing capacity for storage mary occupational health concern, and is achieved and transmission of current data is possible thanks by comparing the efficiency of two biomarkers to as- to technologies such DVD, TV digital, Internet and sess the degree of low exposure to benzenes in the the various techniques of compressing data (MPEG2 working environment. The main reason for this choi- and MPEG4). This ease of access to images and vide- ce lies in the fact that workers occupationally exposed os is allowing video signals to be manipulated with and showing a marked degree of metabolizing the much more complexity within the digitalized com- benzene t-t-MA run a greater risk of developing leu- puter. This new panorama opens up routes for diver- kemia at levels of exposure of more than 1 ppm. In se applications of image processing where the cut- recent times, in Brazil and other countries, a problem ting of the objects is one of the most fundamental affecting workers, companies and the government operations. The cutting consists in using the compu- has become manifest, namely, the serious health risk ter to define, on the image, automatic cuts, around deriving from occupational exposure to benzene. At objects of interest. The intention is to study the best the same time, there is evidence of a risk to the popu- methodology for the development of this software. lation at large because of its dissemination into the In particular, during phase 1 of the research we will environment. The present recommendation of vari- be looking to understand what are the users’ real ne- ous researchers and institutions for the biological eds; what sort of interface there should be; whether monitoring of occupational exposure to benzene, a stand-alone product needs to be generated or falls, principally, on biological markers, trans-trans plug-ins for platforms already in existence; and mucoid acid and urinary phenyl mercaptan acid, at which are the most promising tools.

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Development of Systems for The objective of this project is to carry out of 33 R2/MF Signaling Using practical research in the area of cornea topography New Signal Processing Techniques and the development of the first prototype for intra surgical topography (for use during the surgery), an Coordinator: instrument unprecedented on the national or inter- Carlos Geraldo Kruger national market. As a first step, a system for the pro- jection of cornea rings must be developed, which will Company: perform well during surgery. Its light must not be IDEA! Sistemas Eletrônicos Ltda. obscured by the illumination of the surgical micros- Approved value: cope and the reflection on the cornea must be sharp. Phase 1: R$ 33,300 The projector should be built in the form of three Phase 2: R$ 59,900 / US$ 105,000 acrylic cones. Once assembled, it will be coupled to a fiber optic illumination system with light source in- With this project, the company IDEA! intends to tensity that can be regulated. It is intended to produ- develop an application-specific integrated circuit ce the system in two versions: one for a notebook, (Asic) which, besides encompassing the already exis- and the other for a desktop, both computers to be ting solutions, brings together new functions that IBM-PC compatible. The first will have the advanta- justify its application in low cost terminal equip- ge of being portable; the second will be able to use ment. For this to happen, it is intended to make use image capturing video boards specific to a desktop, of innovative techniques of telephone signal proces- which enable capture of better quality images and in sing jointly with the use of structured project me- real time. The digitalized images will be processed for thodologies, where a high level description is made the detection of rings reflected by the cornea. Algo- with the later use of simulation tools and synthesis. rithms of mathematical models of topography of the Having detected the growing strength of small and human cornea will be applied to the information ob- medium enterprises throughout the world, a rese- tained. Topographical maps, with color codes for dif- arch group, originating from the Telebrás system, ferent curvatures, will be generated and available in decided to create the company IDEA! Sistemas Ele- intervals of a few seconds during the surgery, thus as- trônicos Ltda. Determined to meet and to exceed sisting the surgeon in the diagnosis of surface irregu- their customers’ expectations, IDEA! visited the larities. Cataract and refractive surgeries in general, companies that are important players in the Brazili- are examples for the use of this system. an technology arena and identified the interest of businesses in the telecommunications sector in the development of a low cost Asic component for the Development of an reception and transmission of multi-frequency sig- 35 Endoscope Video Camera nals of type MFC and MFP. As a result, it expects to with an Optical Gradient obtain a low cost component for MFC that will ena- ble the development of national equipment for vari- Coordinator: ous applications, rendering them competitive in the Cícero Lívio Omegna de Souza Filho national and international markets. Company: Kom Montagens e Comércio Ltda. Development of Approved value: 34 an Intra Surgical Topograph Phase 1: R$ 53,387 (first prototype) Phase 2: R$ 113,900 / US$ 79,500

Coordinator: The present project proposes the development of Silvio Antonio Tonissi Junior an endoscope optimized for use as a video camera. Company: The endoscope is an optical instrument that allows Eyetec Equipamentos Oftálmicos Ind. e Com. Ltda. for the observation of locations with limited access. The instrument is composed of a metallic rod and in Approved value: its interior are housed the image optics and a bundle Phase 1: R$ 33,100 / US$ 11,738 of optical fibers for illumination. Its diameter varies Phase 2: R$ 182,223 / US$ 30,950 from 1.8 to 12 mm. The endoscope that we propose Scholarships: R$ 31,500 to develop will be of the rigid type and we will make

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use of technology of graduated lenses (grin lenses). demands with respect to international quality norms These lenses have a cylindrical form and possess a such as ISO 9000, ISO 14000, QS 9000 and others. profile of refractive index that diminishes gradually The laboratory will limit itself to producing stan- from the axis to the cylinder. The use of the techno- dards of pH, ionic activity, conductance, elements for logy of grin lenses, as against conventional lenses, al- absorption and atomic emission, organic com- lows: the use of less lenses, as a consequence less loss pounds for GG, wave length and transmittance for through reflection and accumulated aberrations; spectroscopy of UV, visible and infrared light, and greater precision in the positioning of the lenses pre- primary standards for volumetric analysis. It is im- serving the optical axis of the system, since they pos- portant to emphasize that this project should involve sess cylindrical symmetry; and a smaller tube diame- research which could be utilized in other laboratori- ter, making the inspection of the cavity less invasive. es of the same type and also by official bodies such as Currently the video endoscope requires an additio- the Inmetro, which is attempting to implant bases of nal optical system to link the image of the endosco- chemical metrology in Brazil, mainly for the manu- pe to the CCD camera. Considering the illumination facture of its own standard reference materials and side, the fiber optic cable is interrupted by a connec- the formation of a network of chemical metrology tor placed between the source and the endoscope, accredited and recognized internationally, along the and this connection causes a loss in the order of 50 lines of those already in existence in the Brazilian ca- per cent. In the first phase of this project, we built four libration network (RBC), adopted for the laboratori- prototypes, three of them possessing optical gradient es of physics and mechanics metrology. and one a microvideo-otoscope using conventional lenses. Innumerable gadgets and mechanical tools were made to assemble and test the produced instru- Evaluation of the ments. Efforts in the mounting and development of 37 Residual Water Treatment a new light source integrated with the control unit of System from Cassava Processing a micro camera were experimented with. A special type of fiber was designed and made up with a dia- Coordinator: meter of 40 microns. Using this fiber, beams for the Marney Pascoli Cereda illumination of the prototypes were constructed. Company: Plaza – Indústria e Comércio Ltda. Chemical Approved value: 36 Metrology Laboratory Phase 1: R$ 48,511.70 Coordinator: The present study is part of a project for the ma- Nilton Pereira Alves nagement of residues from the industrialized cassava process, set up by the PRI program jointly by the Bra- Company: zilian Ministry of Science and Technology and the QuimLab – Química e Metrologia French Ministry of Foreign Relations (R$ 29,000.00 (Sesoko & Alves Ltda.) were provided for its development). However, accor- Approved value: ding to the program regulations, those funds could Phase 1: R$ 15,500 / US$ 28,500 not be used for the purchase of equipment, which Phase 2: R$ 56,216 / US$ 121,378 rendered the development of the project impossible. An alternative found was through FAPESP’s Program The objective of this project is to establish a che- for Technological Innovation in Small Businesses, as mical metrology laboratory aimed, mainly, to cater a means of complementing the resources. for industrial companies regarding the supply of in- ternationally recognized chemical standards for the main analytical techniques used in the chemical con- Stereotrips II: Stereoscopic trol of products, processes and the environment. For 38 Computer Graphic Techniques each standard produced a trace certificate will be is- and Synchronized Audio-Video sued, recording the real value of the determined che- for Multimedia Applications mical purity with respect to impurities. The traced standards will be commercialized and will fill the gap Coordinator: in this area in Brazil, principally by fulfilling industry Nelson Coelho Nascimento

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Company: company encountered a large number of viable al- Intuição S/C Ltda. ternative techniques and a total lack of data which would allow the comparison of the methods regar- Approved value: ding quality, reproducibility, cost and the possibility Phase 1: R$ 39,300 of automation. This project aims to overcome this difficulty by means of a comparative analysis of the The present research project has as its objective different techniques currently available in the acade- new research technologies for the presentation of mic world, but as yet not widely used in the indus- high resolution computerized animations accompa- trial environment. This project, during its first pha- nied by music, with a view to launching the product, se, will provide comparative data on the cost and the which should result from this work, on the interna- benefits of these methods based not on theoretical tional market, in particular the United States. Since studies, but on practical use. we are dealing with animations generated through 3-dimensional models, the main emphasis is being made on the study of emergent technologies in the Technological field of real time rendering, such as Direct X®, Innovation for the OpenGL®, and, as well, in the language of VRML 40 Financial World 2.0. The research project Stereotrips II is a continu- ation of the project Stereotrips, carried out in 1996, Coordinator: which consisted of a CD-ROM with stereoscopic Mamede Augusto Machado da Silveira animations accompanied by music. Ten stereoscopic animations were made, each with its respective mu- Company: sical accompaniment, run on a piece of software es- JRM Informática Ltda. pecially created for this purpose, on the PC-Win- Approved value: dows platform in 16 bits programmed in Visual- Phase 1: R$ 50,264 Basic language. This CD could also be played on conventional audio CD players. The software in this The objective of this project is to study the techni- case used DLL routines freely distributed and crea- cal viability of a computerized structure capable of ted by the Autodesk company. The basic feature of meeting all the storage and processing requirements Stereotrips is simply the stereoscopy of the animati- of the corporate information of a financial instituti- ons, which provides the illusion of 3-dimensiona- on, in a single, integrated form. Furthermore, this lism on two-dimension support without the need structure should serve as an embryonic tool for un- for glasses or any other device, requiring nothing dertaking the re-engineering of the institution’s busi- more than the common multimedia computer. ness processes. The requirements for the success of a company’s strategic plan are effected only if the sys- tems that support their businesses are able to make DNA Automatic Sequencing in fast changes, with real-time access. Consequently, it is Molecular Diagnostics: Analysis of 39 necessary to re-think information technology soluti- the Efficiency, Reproducibility ons in such a way as to converge and support all of the and Costs of Different Methods business processes (flexible and adaptable) and the information technology needs of the company. For Coordinator: this to occur, a model of an integrated system must be Heloísa Barbosa Pena built, with the following prerequisites: integration in a Company: single system of all of the institution’s data and busi- Genomic Engenharia Molecular Ltda. ness processes; total portability between various cli- ent/server platforms; easy scalability of applications Approved value: between few or many users; inter-operability between Phase 1: R$ 47,600 the diverse open standards of the information tech- nology market; the possibility for the extension of the The Genomic Engenharia Molecular company model for the inclusion of new types of complex data specializes in the development and commercializati- and new products; offers the possibility of gradual on of diagnostic tests in medical, veterinary and migration from the institution’s existing systems; mi- agricultural areas using molecular biology techni- nimizes costs; offers a user friendly graphic interface ques. During the process of setting up diagnostic capable of manipulating and bringing on screen com- tests based on the automatic sequencing of DNA, the

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plex data; establishes a technology plan for the finan- Company: cial institution for the next decade. Proqualit Montagem e Comércio Ltda. Approved value: Phase 1: R$ 19,900 / US$ 7,206.40 Metropolitan Phase 2: R$ 155,800 / US$ 20,000 41 Wireless Network – Wireless MAN The present project consists of the complete specification of a low noise level amplifier with fre- Coordinator: quency converters in KU Band (satellite television) Oséas Valente de Avilez Filho Low Noise Block (LNB) for the features currently Company: used on the national market by the operating com- Josaphat Engenharia Ltda. panies of the DTH (Direct to Home) system: Sky (Globo Group) and TVA (Abril Group). Thereafter, Approved value: a theoretical project should be developed that will Phase 1: R$ 39,111.11 attempt to solve the problem of the balance between the specified impedance for the minimum noise Our proposal is to present an alternative to the level and maximum gain in high frequency (12 rationalization of water consumption and electrical GHz) and for the variations in the environment energy, that consists in the development of a system temperature (-10°C to 50°C). Once the theoretical the objective of which is to better distribute the con- electrical project is defined, in accordance with the sumption of these resources throughout the day. As diagram of the blocks to follow, a mechanical pro- is known, there are consumption peaks that define ject enclosing the box and attaching the reflector the capacity of distribution networks. If consumpti- should be carried out. Diagram of blocks of LNB: on were better distributed, the peaks would be redu- Zin 1 = Zin 2; Zout 1 = Zout 2; O.L. = Local Oscil- ced and as a result, existing networks could be re-di- lator, and LNA = Low Noise Level Amplifier. The mensioned and maximized, there no longer being next step will be the mounting of the components, the need for large investments in new networks, ge- thus obtaining the first prototype of this printed nerating in this manner, a huge benefit to environ- circuit plate made in the country. Shortly after- mental conservation. Brazil has an enormous poten- wards, tests must be carried out on the performance tial of natural resources. Despite this, serious of the mounted PCP (Printed Circuit Plate). After problems related to shortages of fresh water and the evaluation of the performance, possible modifi- electrical energy, have begun to appear. With the on- cations to the PCP will be made, which must be line monitoring forecast in this project, other gains integrated with the container box and the reflector will be obtained: a reduction in physical losses (le- for new performance tests. The final evaluation aks, diversions, etc.) and non-physical losses (billing must be carried out on the whole assembly: evasion) and the detection of critical situations, ma- parabolic reflector + LNB + receptor. The conclu- king possible prompt corrective action in the distri- sions to this project should indicate the best solu- bution systems. Currently, the Brazilian market has tion for the mass production of this product. This no available system capable of monitoring the sup- study could also generate important procedures for ply networks. Our initial goal is to meet the needs of projects on frequency converters to be applied in this market, and in the future, to export the techno- other telecommunications systems. logy and the developed products to other countries. The Metropolitan Area Network (MAN), the main objective of this project, will be a low velocity, wire- Inertial Sensors less network using Spread Spectrum techniques and Integrated Platform/ code division multiple access (CDMA). 43 Global Positioning System (GPS) Low Noise Amplifier with 42 Frequency Converter in KU Coordinator: Band (LNB – Low Noise Block) Otávio Santos Cupertino Durão for Use with Parabolic Reflectors Company: Navcon Navegação e Controle Coordinator: Indústria e Comércio Ltda. Alexandre Nunes da Trindade

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Approved value: using a structure of hollow cathode discharges and Phase 1: R$ 23,635 / US$ 21,929 superficial treatment of ferrous elements in substi- Phase 2: R$ 111,739 / US$ 45,564 tution of the conventional galvanization processes. These processes were chosen due to the fact that they This research project is looking to integrate, on a require few modifications to the existing processing single platform, inertia sensors and a low cost GPS re- unit, as well as their high content of technological ceptor, with the aim of determining trajectories and innovation and their large commercial potential, gi- position. Besides the mechanical integration, algo- ven that they are part of a virtually untapped niche rithms, processing and the treatment of the necessary market in Brazil. Though there is equipment (from signals will also be implemented. As a result, we ex- foreign companies) available on the market, Metal pect to have, on a small-dimensioned, low mass plat- Plasma chose to develop its own reactor, since ad- form, a unit capable of offering better results than vanced technologies require constant changes and those of its components (GPS and inertia sensors) adaptations. The first processing unit consists of a when working in isolation but with same purpose. In high vacuum stainless steel chamber with a useful addition, the integrated platform will overcome the li- volume of 120 liters, a Roots Pumping System with a mitations these components have when acting in iso- flow rate of 150 m3/h, a 30 kW electrical source and lation. Continuous use of isolated GPS receptors, for an admission system for Ar, N2 and H2 gases. Taking example, is not possible, due to temporary geometric the project forward, phase 2 will entail applied rese- restrictions of its positioning. Other causes of tempo- arch studies in order to develop the selected proces- rary loss of GPS signal occur due to errors in signal ses, in order to reach the quality standards that will transmission. Also, the frequency of the GPS receptor allow its use on a commercial scale. Basically four reader is insufficient in certain cases, and this fre- experimental techniques will be used in the investi- quency will be substantially increased when it is inte- gation of the plasma: atomic emission spectroscopy, grated with the inertia sensors. The integration of atomic absorption spectroscopy, mass spectrometry these two pieces of equipment eliminates these defici- and current flow. encies. Phase 1 of the project analyzed the viability of this integration for a wide range of applications. As a result, in phase 2, the intention is to build a pre-indus- Development trial model of the system that has modular characte- 45 of a Plasma ristics. That is, attention will be paid to different ap- Sterilizer plications and precision specifications, allowing for the modular substitution of some of the system’s Coordinator: components, notably the inertia sensors board. In this Tadashi Shiosawa way, low precision applications can be handled with Company: low cost sensors, without this preventing the use of Valitech Ind. e Com. Ltda. the system in other higher precision applications, pro- vided better quality sensors are used. Approved value: Phase 1: R$ 36,600 Phase 2: R$ 111,290 / US$ 18,494.75 Development of 44 Plasma Processes This project entails the development of a sterili- Applied to Metallurgy zer for contaminated surgical, odontological and packaging materials, through the use of plasma tech- Coordinator: nology. The development will be done in stages. In Vladimir Henrique Baggio Scheid the first stage, market research will be carried out, looking at the technical viability and marketability Company: of the process to be developed. In this phase contacts Metal Plasma S/C Ltda. and visits will be undertaken to companies and ins- Approved value: titutions that use surgical, odontological and packa- Phase 1: R$ 49,000 ging materials in general which need to be sterilized before use, aiming to obtain information about the- The objective of this project is the development se materials such as their physical and clinical pro- of the following processes of plasma application in perties and the level of sterilization necessary. Paral- metallurgy: plasma nitration of non-ferrous ele- lel to this, a prototype sterilizer will be built, where ments, deposition of films of Al2O3, TiN and TiC by the conditions of the plasma discharge of some gases

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will be investigated. Once the parameters for the lu- Development of minescent discharge (plasma) have been defined, 47 Semiconductor Laser and taking into account the results of the market re- Equipment for search, a sterilizer will be built in which tests on the Medical Applications elimination of standard bacteria will be carried out as well as studies of the effect of the plasma on the Coordinator: sterilized material itself and the determination of the Sergio Celaschi best conditions for luminescent discharge sterilizati- Company: on. From the results of this research project, our ul- Ecco – Fibras e Dispositivos timate goal will be to manufacture a plasma sterili- zer that meets the needs of the market. Approved value: Phase 1: R$ 45,500

Development of Modular The objective of this research is the design, deve- 46 and Configurable Equipment for lopment and surgical testing of prototypes of three the Capture and Digital portable pieces of equipment for laser operations, Processing of Biological Signals each one of them consisting of a diode laser semicon- ductor with a radiation source. Cables and optical Coordinator: probes for specific applications will be optically lin- Luiz Antônio Barbosa Coelho ked to the main parts of the prototypes. In addition, a visible optical sight will be located on the same op- Company: tical exit cable. The first clinical tests of the prototy- Lynx Tecnologia Eletrônica Ltda. pes are forecast for ophthalmological, dermatological Approved value: and acupuncture operations. The main application Phase 1: R$ 49,800 for the three categories of equipment are: low power (between 50 and 200 MW) – for bio-stimulation, The project intends to specify and to develop a with analgesic, anti-inflammatory, anti-spasmodic system of capturing and processing biomedical sig- and vasodilatory effects; medium power (between 1 nals based on modular hardware and totally configu- and 3 W) – for ophthalmological and dermatological rable software that offers both high performance and treatments, and high power (between 15 and 20 W) a high degree of flexibility. This system will be based – for general surgery. The methodology of the study on modules of simple and standardized hardware and envisages handing over the prototypes to university from groupings of which a high processing capacity hospitals for clinical and medical testing. We expect in numbers of channels and a high degree of sam- to demonstrate the viability of designing and assem- pling can be obtained. Particular emphasis will be gi- bling three portable medical prototypes for laser sur- ven to the configurability of this system, allowing for geries. Two of them will be designed and mounted its use across a wide range of applications, as well as for operations at 810 nm, and one of them (an inno- its easy adaptation to other types of application, even vation) will emit close to 0.5 W of power at 405 nm. outside of the biological area. Consequently, the short This wave length will be obtained by doubling the ef- term goal is: to specify the design of the distributed ficiency of its primary frequency. The main applica- system of capturing and processing (biological) sig- tions are expected to be in bio-stimulations, with nals capable of processing up to 64 channels, with a analgesic, anti inflammatory, anti-spasmodic and va- sample frequency of 20 kHz per channel with presen- sodilatory effects, for ophthalmological and derma- tation and digital filtration of the signal in real time tological treatments as well as general surgery. under the control of a microcomputer, and to define a high performance communication protocol betwe- en the microcomputer and the acquisition modules Transportable and the digital processing of signals, and to formulate Odontological Module processing algorithms in real time for application in 48 neurophysiology. In the long term, the intention is to Coordinator: consolidate technological training within the project Alexandre de Oliveira Rangel as well as the implementation of capturing and digi- tal processing systems of high performance signals. Company: Oral Health – Oliveira Rangel & Camargo Jr. Ltda.

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Approved value: with good results, in a master’s thesis. However, this Phase 1: R$ 19,007 development was too specific and it was not possible to incorporate this feature in the Cappe solution – The objective of this project is to develop a mo- something the present work is attempting to remedy. bile odontological module, fitted with simplified The results of phase 1 demonstrated the technical vi- equipment, easily carried from one location to ano- ability of the proposed solutions. The objective of ther, so as to offer odontological services directly to phase 2 is to complete the implementation of a pro- the more needy areas. Today, mobile dental health totype resulting from phase 1, with emphasis on the teams are already a reality and have been established details of the integrated process of CAD, multi-lan- in various Brazilian municipalities based fundamen- guage working, integration with ERP, three layer de- tally on Clinical Modular Transportable Systems. sign and visualization of the plans via the web. These teams move about in order to assist priority population groups. For example, they visit primary and secondary schools within the municipality on a Application of Conductor rotating basis, providing an initial service for first 50 Polymers as Gas Sensors grade primary children and yearly checkups on stu- dents in the other school grades. Today, with their Coordinator: accumulated experience, in addition to teams dedi- Milton Soares de Campos cated to the care of children and adolescents, one Company: can imagine mobile teams, working through a trans- Toró e Toró Ltda. – ME portable clinical module system, meeting the needs of special groups such as the elderly, pregnant wo- Approved value: men, factory workers etc. Phase 1: R$ 49,500

The objective of this project is to use the rectifi- Development of cation properties of conductor polymers for the 49 a Generic Planning Solution construction of sensors for methane and ethylene of Automatic Processing gas. For this, two types of polymer will be used, which for Parametric Parts are very stable under environmental conditions, polypyrrole and polythiophene. Schottky diodes will Coordinator: be constructed using these polymers (doped with Haroldo Thomaz Kerry Junior protonic acid), both in the planar configuration (with two metallic electrodes deposited by litho- Company: graph or silk screen on the same face of the polymer) KSR Com. de Materiais e Componentes and in the sandwich configuration. Metals with a para Informática e Consultoria Ltda. work function that forms ohmic and blocking con- Approved value: tacts with the polymer will be used. Studies of the Phase 1: R$ 15,561 electric current as a function of the DC voltage, both Phase 2: R$ 66,241 in the forward direction and reverse, in relation to humidity, temperature and gas concentration, will The goal of the present research work is to ena- be carried out using doped and non-doped poly- ble the Cappe (Computer Aided Process Planning mers. Their sensibility, reproducibility and stability Environment) information technology system alre- will also be investigated. We expect to collect suffici- ady developed by KSR, to become an automatic sys- ent information for the construction of a sensor for tem for parametric parts in general. KSR is a part- ethylene and methane gas. Despite the agricultural nership of former University of São Paulo (USP/São sector being one of the most dynamic in the natio- Carlos) students who, five years ago, with experien- nal economy, one of the serious problems still is the ce gained in the area of Capp (Computer Aided Pro- storage of agricultural produce. It is estimated that cess Planning), set up the company with a view to close to 25 per cent of the total production is lost ye- filling a gap they detected in the international indus- arly through decomposition and fires that occur in trial automation market. Shortly afterwards they grain silos, probably caused by the formation of in- launched the Cappe system. However, this system flammable gases such as methane. In the case of the does not support automatic generative planning, controlled stocks of fruit, their maturing is caused and this represents a serious limitation. An automa- by the formation of a hormone which on decompo- tic solution for parameterized parts was developed, sing forms the gas named ethylene.

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Development of Devices Approved value: 51 in CVD-diamond for Short Phase 1: R$ 48,000 Term Applications Phase 2: R$ 199,800

Coordinator: Phase 1 of this research project aims to build a Kiyoe Umeda collection of totally original prototypes for the ma- nufacture of plastic, magnetic, inductive, smart cards Company: and transponders entirely from national compo- Clorovale Indústria e Comércio de Cloro Ltda. nents, that offer ease of operation and maintenance, Approved value: high productivity, and considerably lower cost com- Phase 1: R$ 26,335.50 pared to the technology available on the internatio- Phase 2: R$ 109,000 / US$ 76,485 nal market, in addition to levels of quality and secu- rity compatible with international standards, to be The objective of this project is to carry forward used in information technology systems. In phase 2, the research and development work of the National we will aim to reach the stage of manufacturing of Space Research Institute – Inpe and of the São Fran- magnetic credit cards and smart cards on an indus- cisco University – USF, in a small company, with the trial scale. The innovation for the second phase, will real possibilities of achieving the industrialization of be a system of authentication and security for tran- products manufactured from CVD-diamond. This sactions through public networks (Internet/fax/tele- artificial diamond has properties equivalent to natu- phone), named Security Smart Card. The aim of this ral diamond, with the advantage of being made avai- product is to offer to companies the ability to ex- lable in the form of fine and thick films on small sur- pand, securely, via computer networks. These pro- faces (less than 1 mm2) and large surfaces (greater ducts will have three main elements: software with than 100 cm2), in different formats. The company the authentication of an electronic signature and itself already produces hydrogen gas, the most ex- dynamic passwords generated by a cryptographic pensive raw material for the process of growing key, a smart card reader connected to personal com- CVD-diamond. Within this objective, there is the puters and personalized smart cards manufactured need for the assembling of a reactor for growing, on by the company, with the innovation of combining large surfaces, with a system of recycling/reusing of smart card and inductive card technologies. We will the gas adjusting the reactor to higher growth rates, be dealing with an inductive relay with metallic prin- appropriate to industrialization. To be able to make ting, with mechanisms for insertion of tracks and sa- use of the company’s hydrogen, it will be necessary feguards within the internal part of the card. to set up a compression system for this gas, allowing its escape into the appropriate receiving vessel. With this new reactor concept, there is a need to research, 3rd BIDDING INSTRUCTIONS on an industrial scale, the new growth parameters in relation to quality, rates of nucleus and film growths to be produced on some types of substrates. At the Technological heart of this research, there is a desire to develop and 53 Modernization of place on the market, devices such as mechanical pro- Optical Amplifiers bes, cutting edges for plastic materials and non-fer- by Erbium Doped Fiber rous metals, orifices and tubes in CVD-diamond, drills for odontology and related uses, as well as win- Coordinator: dows for optical protection. Ildefonso Félix de Faria Junior Company: AGC – Optosystemas Ltda. Manufacture of Credit Cards, 52 Open and Closed Plastic Cards Approved value: Phase 1: R$ 8,300 / US$ 37,000 Coordinators: Phase 2: R$ 74,600 / US$ 106,460 Wellington Gomes de Andrade / Amador Poceiro Orelo The objective of this project is the improvement of the technology of Optical Amplifiers by Fiber Do- Company: ping with Erbium (AFDE), as well as the establis- Tecnocard Tecnologia em Cartões Ltda.

Translating Research into Business • 95 hment of a laboratory, dedicated to the product. AF- acid H3PO4 occurs to the degree of that used as a fer- DEs are pieces of equipment for the amplification of tilizer (aqueous phase) with a cooled solution of iso- optical signals transmitted via optical fibers, fed by a propyl ether/ tri-butyl phosphate (organic phase). source that is also optical (semiconductor laser, high The residue produced from this phase is called raffi- powered optical electronic devices). We are dealing nate, which is rich in compounds of phosphate not with a technology initially developed by the Center available for extraction, generally metallic phospha- for Research and Development of Telecommu- tes of Mg2+, Fe3+ and Al3+, deriving from the phos- nications (CPqD/Telebrás) and that has undergone phate mineral. The process is now looking to impro- technological modernization over the last six ve on the extraction process operations of the pilot months. The fundamental changes in the initial pro- plant with a reactor and a Kuhni column, where the ject were the design of an electronic control system acidification using sulfuric acid from the raffinate based on micro-processing circuits and the cons- occurs, followed by extraction with the solvent of truction of a measuring device that allows the moni- phosphoric acid. The acidification with the stronger toring of the internal parameters of the amplifiers, as acid frees the phosphates in the raffinate, increasing well as the current and temperature of the base laser; the yield of the process. In the extraction process, the optical potential at the entrance and exit of the am- phosphates must present themselves in the form plifier; RS232 interface for interlinking with the su- H3PO4 in order for the transfer from the aqueous pervision and management systems of telephone ex- phase to the organic solvent phase to occur. With in- changes. For the second phase, the development will creased efficiency in the process, it will be possible to be taken forward, concentrating attention on the reduce the cost of the final product. module of optical gain. Special filters will be used so as to equalize the optical gain in the operational band which, in addition to producing a planar gain, Optimization and will allow a small broadening of the amplifier’s opti- 55 Classification Project on cal band. Special optical fibers will be used and also Biodegradable Polyurethane Foam a rounding design to produce amplifiers in the opti- cal band of 1570 to 1610 nm, band L). Coordinator: Eduardo Murgel Ferraz Kehl Company: Studies of Acidification Eduardo Murgel Ferraz Kehl – ME 54 of Raffinate in Kuhni column, to Increase the Yield in the Approved value: Phosphoric Acid Purification Process Phase 1: R$ 39,965 The objectives of this project are to improve the Coordinator: physical-chemical properties of the product BioEs- Roberto Corrêa de Cerqueira César puma (BioFoam), its parameters of production, to Company: determine the quality system, to analyze its behavior Fosbrasil S/A regarding properties of biodegradation and as a substrate for the growth of plant cuttings. Once the Approved value: parameters are defined, the intention is to produce Phase 1: R$ 46,000 and sell the possible products obtained, such as pac- kaging, and the intermediate raw material (polyol) The objective of this process is to increase the ef- targeting a profit margin greater than 20 per cent. ficiency of the liquid-liquid extraction in flux pro- The company’s philosophy has always been to give cess for the purification of phosphoric acid, which priority to using processes, the raw materials of has been successfully used for the last 13 years by which can be obtained from the agriculture/farming Fosbrasil, which is the only Brazilian company to industry, which aim towards products of large con- have mastered this cutting edge technology, posses- sumption. From castor oil and other derivatives of sing in its premises a pilot plant where it has already the agriculture/farming industry a semi-rigid foam carried out various tests with raw materials, impro- (basically of polyurethane) has already been obtai- ving and implementing changes in the purification ned, which is biodegradable. The product was paten- process. The purification process, via extraction, is ted as BioEspuma. The objective now is to work out divided into three stages: extraction, cleaning and the details of a production process and a quality re-extraction. In the first stage, the extraction of the control system which meet the ISO 9000 and ISO

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14000 standards. In five years, it is intended to pro- Approved value: duce a quantity equivalent to 2 per cent of the cur- Phase 1: R$ 27,546 rent consumption of packaging material. Presently, this would be around 300 tons/month or US$ 1.5 The present project’s objective is to study and de- million of monthly income. Another objective is to velop processes for the recovery and recycling of lu- triple market share during a second five-year period brication oils, additives and high density polyethyle- of the project, generating, in this manner, sufficient ne (HPDE) originating from leftover bottles at gas resources for investment in the area of production stations. In addition, a further objective is to develop technology. The objective is to use the family work- systems for the capture of this raw material with a force of small producers for whom the cultivation of view, ultimately, to developing a viable program for the castor bean on a consortium basis would provi- the return to a useful life of these residual pollutants. de an alternative to traditional crops. The tests on Therefore the studies involve: the verification of the cutting growths will be in the form of observing and procedures most appropriate for the capture of recording growth from the seeds. throw-away bottles; the verification of the frequency necessary for the removal of collected residues; studi- es of the processes of decontamination of the HPDE Development of Coatings bottles, with the removal of the residual oil and of fo- 56 Intended for the Use of Organic reign material (tops, seals, paper); improvement in Corrosion Inhibitors and to a the HPDE recycling process; improvement in the Reduction in the Use of Solvents recycled granules (HPDE) production process, as well as the production of plastic bottles from granu- Coordinator: les of recycled HPDE. Brazil consumes per year close Lorenzo De Micheli to 900 million liters of lubricant oil, of which 60 per Company: cent is for automobile oils and 40 per cent for in- Reade Revestimentos Especiais dustry. During its use, part of the lubricant is burned de Alto Desempenho Ltda. or incorporated into the final product, leaving some- where between 250 and 300 million liters of waste oil Approved value: per year. Only around 100 million of liters of this oil Phase 1: R$ 7,500 per year go to refining. The remainder is discarded into the ground or into water or burned, almost al- This project proposes a reduction in the use of ways in an inadequate manner (one liter of oil is ca- solvents in coatings through the use of a thermo-fi- pable of removing the oxygen from 1 million liters of xing resin (epoxy resin) with a high level of solids and water). Gas stations discard into the environment the use of non-toxic organic inhibitors in place of the HPDE bottles contaminated with lubricant oil and conventional organic compounds. Research and de- additives. Since its biodegradable rate is extremely velopment in the area of coatings in Brazil is very low (over one hundred years) these bottles reduce the small. Even today, industrial companies are using very useful life of rubbish dumps and landfills. old formulae that work, but which ignore environ- mental issues. With increased demand from Brazilian society for the manufacture of products which do not Development of a damage the environment, it is now becoming neces- 58 Self-Propelled sary to research coatings which are longer lasting and Sprayer/Duster for have a lower level of solvents in their composition. Treatment in Citrus Orchards Current coatings on the market normally contain to- xic inorganic inhibitors based on lead or zinc. Coordinator: Tomomassa Matuo Technological Innovation Company: 57 in the Recycling of Plastic Bottles Herbicat Ltda. from Gas Stations Approved value: Phase 1: R$ 36,700 Coordinator: João Antonio Galbiatti The present proposal intends to develop a self- Company: propelled duster for the treatment of citrus orchards Comércio de Ferro Velho Moretti Ltda. entirely mounted on a modified tractor, with the ob-

Translating Research into Business • 97 jective of obtaining greater efficiency in the work of the basic parts of a complete collection system, and in the treatment, of gaining better maneuverabi- transmission and analysis of the biological parame- lity, greater height – in order to have more favorable ters such as electrocardiogram (ECG) and blood pres- angles for covering the high parts of the plant –, to sure (BP), the emphasis changed towards a philo- diminish losses during the application and to im- sophy of horizontal development where the system is prove the security and comfort of the operator. An put into a working situation with all of its parts avai- important objective is to minimize losses, leading to lable, and progressively amplified. What remained for reduced production costs, less environmental conta- the final part of the 2nd phase was the stochastic mination and greater safety for the operator. The in- analysis of the parameters collected over long periods tended sanitization treatment of citrus trees is one of of time. In Brazil, sudden death from cardiac arrhyth- the main production cost components, accounting mia (“cardiac arrest”) is the greatest cause of death in for more than a third of the overall cost. The use of the adult population. The introduction of the Holter the plant-sanitization products applied to the crown exam, in which 24 hours of ECG are continuously re- of the tree (insecticides + acarus killers + fungici- corded in the normal environment of the patient, re- des), during the year 1996, absorbed close to US$ presented an advance. Nevertheless, a significant part 120 million. In spite of the intensive use of sanitiza- of the ECG information is not utilized. This arises tion products, the operation of phytosanitary treat- from the failure to analyze day-to-day variations. The ment is characteristically extremely wasteful. Losses proposal is to use the support technology already de- during the application by mechanized process using veloped by the company namely digital Holter recor- turbo atomizers, which is the principal process, are ders and software, to analyze the arrhythmias on the in excess of 63 per cent. In 1988, we presented a mo- ECG, to create a teleprocessing center that will allow del of an applicator that made use of various basic ECG monitoring over extended periods of time components through the use of which the loss was (more than two weeks), and to improve and test pre- reduced to 24 per cent. This invention won an award viously studied models of dynamic analysis. at the XV National Convention of Brazilian Inven- tions, receiving the “Governor of the State of São Paulo” Award. Applications of Cooperative 60 and Communication Work for Educational Institutions Estocastic Analysis of 59 the Temporal Dynamics Coordinator: of Cardiac Arrhythmias Rodrigo Cascão Araújo through Intermittent Recording Company: of an Electrocardiogram, RAM Computer Systems – for Very Long Time Periods Consultoria em Informática S/C Ltda. Coordinator: Approved value: Ricardo Geretto Kortas Phase 1: R$ 33,000 Company: This project’s objective is the implementation of Kiim – Kortas Informática Instrumentação a computerized system for applications in coopera- Médica Ind. Com. Imp. Exp. Ltda. tive and communications work specific to educatio- Approved value: nal institutions via the Internet. The top priority of Phase 1: R$ 30,200 this system is to offer these institutions an alternati- Phase 2: R$ 183,900 ve that overcomes existing obstacles. The system must be simple, efficient, functional, comprehensive, Phase 1 of the project aimed to analyze intermit- and easy to administer and operate. With the ever- tently recorded electrocardiograms (ECG), over a expanding use of the Internet, the worldwide com- long period of time, in order to obtain a better un- puter network, educational institutions have increa- derstanding of the spontaneous variability of the car- singly begun to exploit its potential for accessing and diac arrhythmias, with consequent improvements in publishing information, cooperative work and com- the estimation of the risk of arrhythmias and in the munication. However, there still are three obstacles use of anti-arrhythmia drugs. Subsequently, since this that create difficulty or impede this use: the diversity phase enabled the development and implementation of standards and the absence of a single operating

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environment; the demands for a broad body of tech- tem and the work controller. Mapping of the tar- nical knowledge for use with these existing environ- gets will be carried out by means of prior passage of ments; and lack of mechanisms that promote the the equipment over the areas of application, at participation of parents, teachers, pupils, and mem- which time the operators will collect information bers of other institutions in the single collaborative about the targets, using special keyboards. The na- context. The proposed system would be structured vigation software will receive the signals from the in a manner so as to simulate the working of a tradi- DGPS (Differential Global Positioning System) and tional school. All of the modules should be accessi- from radar (positioned with reference to the ble via an initial common interface: the web browser. ground), providing information of position and It would need to allow the publication of documents time, which will enable the generation and reading independent of platform and the format in which of the geo-referenced maps. The target maps will be they are created. Its users should be able to make use transformed into treatment maps with the help of of it from any part of the world via the Internet. It a support and decision system, which corresponds should allow the exchange of information between to SGI (system of geographical information) struc- various institutions and the publication of internal tured in layers, with the ability to manipulate diffe- activities of the institution for public access. rent data banks with support information for the mapping. The work control system will simultane- ously read the treatment maps and position the Development of duster, generating information on the dosage ne- 61 Systems for Localized and cessary and the precise location of application, Rationalized Application of which will be passed on as commands to the injec- the Technology of Herbicide tion systems and the pulverized bars. The injection Application for Railroads systems will receive the information and will mix the herbicide in the water in the necessary propor- Coordinators: tions and at the correct time. Ulisses Rocha Antuniassi / José Armando Furlani Junior Technological Development Company: of Special Compact Autonomous Infrajato Engenharia Ltda. 62 Air-Conditioning for Use in Approved value: Microenvironmental Cabinets for Phase 1: R$ 36,319 / US$ 8,527.50 Animal Testing Laboratories Phase 2: R$ 52,600 / US$ 31,026 Project Coordinator: This research project aims to develop and eva- Habib Guy Marie Nahas luate new techniques and equipment for the appli- Company: cation of herbicides. It is intended to bring together Hvac Engenharia e Comércio Ltda. advanced technologies relating to the selection of snouts, construction of duster bars, electronic ma- Approved value: nagement and localized application. In addition, Phase 1: R$ 61,000.00 the project seeks to train the proposing company’s personnel in order to offer services in the control of Conventional air-conditioning equipment on nuisance plants on railroads and the development the market fails to meet the technical requirements and employment of concepts of localized applicati- when used for thermohygrometric control and of on of agricultural herbicides in general. In this se- levels of ammonia of the interior ambient air of the cond phase, we propose to build a piece of equip- microenvironmental cabinets. These conventional ment for the localized application of herbicides and pieces of equipment are sized merely for macroen- the implementation of an improved control system vironments and for human comfort, not meeting of nuisance plants on railroads, following the con- the requirements of animal testing laboratories. The cepts of precision agriculture. The system will be proposed equipment would provide the correct si- based on an on-board computer to be installed in zing of volumes of air in the air-conditioning sys- the cabin of the applying equipment, which will tem for heat exchanges between the interior and the consider three main questions: the generation of exterior air, as well as the safe dilution of the ammo- the target maps for application, the navigation sys- nia vapors generated by the animals. Also envisaged

Translating Research into Business • 99 is the sizing of a piece of equipment with air con- ting in an oven with alternating flows of (water va- densation, autonomous working, totally automatic, por + air) and (water vapor + oxygen). Virtually microprocessed, easy to regulate from the point of pure synthetic nsutites were obtained, with the operation, with visual temperature and relative hu- structure of y-MnO2 and with a density of around midity indicators, including batteries for warming, 1.2 g per cm3. In phase 2, the intention is to build a humidifying and filtering of air, electro-electronic rotating heating vessel with sections for the heating controls, silent working and of small dimensions, of rhodochrosite in an atmosphere of (air + water), able to cope with a maximum of two microenviron- with a chimney for the escape of gases, as well as mental cabinets. Installation is envisaged for a win- density increasing sections, on a production scale of dow and/or hole in the wall, with ease of operation some 100 Kg/hour. and preventative and/or corrective maintenance. The result is important for the enhancement of ani- mal testing processes and for the guaranteed quality Applications of of the experiments and/or scientific results. 64 Lasers in Materials Processing

Obtaining (gamma) Coordinator: 63 MnO2 for use in Spero Penha Morato Batteries from Different Company: Manganese Compounds LaserTools (Incubated at Cietec/Ipen) Coordinator: Approved value: José Vicente Valarelli Phase 1: R$ 24,300 / US$ 20,600 Phase 2: R$ 87,500 / US$ 70,000 Company: Fermavi Ind. e Com. de The objective of the present proposal is, during Prods. Químicos Ltda. the first Phase, to develop methods and advanced Approved value: procedures for the use of Ipen’s Central Processing of Phase 1: R$ 66,926 Material by Laser (CPML) as a processing instru- Phase 2: R$ 182,390 ment (cutting, drilling, soldering and surface proces- sing) for industrial materials (steels, ceramics, silicon This project proposes the evaluation and the im- etc.). It is also expected to identify those sectors of the proved use of manganese minerals in Brazil through metal/mechanics industry that are potential candida- the development of processes that converge towards tes for the use of the CPML as a job shop for the de- obtaining gamma-MnO2 (nsutite) used in the ma- velopment of processes and for the delivery of speci- nufacture of Le-clanche and Alkaline type batteries. alized services in the areas of tooling and welding. In In phase 1 proposals were made for methods of ob- the medium and long term (phase 2), this proposal taining y-MnO2, with a structure of nsutite from dif- looks towards the use of a CO2 laser as a comple- ferent raw materials. Two of them achieved good mentary tool for the processing of materials in line performance, but only one of them is recommended with results obtained with the CPML. In this second for development. Conversion of the natural mine- phase, the objective is to develop and consolidate me- ral from the Raizama Mine in the municipality of thodologies and laser processes for use in industrial Cavalcanti, GO, was carried out. The mineral is es- applications of greatest demand. For this purpose, it sentially composed of Hollandite (BaMna016). The is intended to lay the foundations of a job shop at La- mineral was ground up and submitted to enclosed serTools,that will offer the productive sector an array heating, transforming it into Hausmannite (Mn3O4). of laser tooling services. Currently the main industrial This was followed by aqueous leaching with the sig- uses of lasers are for cutting materials. However, nificant elimination of Barium. The conversion of other types of work using a greater variety of materials Hausmannite into nsutite was successfully achieved. have expanded considerably. LaserTools is a limited However, the method proved not to be economically company of shareholding partners who are involved viable. Studies concentrated on the conversion of directly or indirectly in developments undertaken in synthetic rhodochrosite of high purity, through hea- Ipen’s Division of Applied Optics.

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4th BIDDING INSTRUCTIONS Company: Aluísio Pimentel de Camargo - Micro Company Approved value: SISOFT 14001 – Phase 1: R$ 44,000 65 Software for Supporting Phase 2: R$ 171,067 / US$ 8,984.70 the Preparation of an Environmental The present piece of research consists of develo- Management System ping new types of generator intended to increase the efficiency of ozone production. Matters relating to Coordinator: the lowering the cost of the generator production Sahadev Anantha Krishnan and the consumption of electricity in its operation Company: will be studied. Taking into account the climatic Biotec Assessoria e Serviços Ltda. conditions prevailing in Brazil, the operational diffi- culties of installing ozone generators available in the Approved value: international market, allied to their high cost, the Phase 1: R$ 28,294 purpose of the project was, in the initial stage, sim- ply to develop technologically a high-performance The present piece of research is intended to set ozone generator. The work was carried out based on up and develop SISOFT 14001 software, an informa- conventional ozone generators, produced commer- tion technology tool intended to offer the following cially by the company Qualidor Saneamento Incor- facility: to set up an environmental management poração. The generators were developed based on system (EMS) in a company, step by step; to manage cylindrical cells where the ozone production is based the daily tasks required by the EMS through an au- on electrical discharges with specially prepared die- tomated tracking and documentation system; to cre- lectric barriers to obtain high productivity, with a ate an audit (due-diligence) system; to facilitate the high concentration of ozone and low electricity con- online exchange of information within the organiza- sumption. Systems appropriate for drying and purif- tion, and to facilitate the management decision-ma- ying the air were developed as an integral part of the king process. Sispamte software, developed and sold generators, achieving relative air humidity of close by the company Sensora Sensoriamento e Geopro- to zero and a dew point of less than -40° C. This con- cessamento, will be used as the basis. This is a system cept of implementing an air purification system is a for recording data and producing cartographically determinant factor in adapting the generators deve- referenced information and it is noted for its logical loped to this country’s climatic and atmospheric structure and ease of use. The implementation of an conditions in order to ensure appropriate degrees of EMS brings various advantages, among which are: productivity and durability. The air humidity pro- credibility, lower risk, and less pollution; increased duces nitric acid during the production of ozone, profit margins, and an improvement to the internal damaging both the equipment and the environment. management system. ISO 14001 standard supplies The most important result of the First Stage of this the specifications for developing an environmental project was to complete building an experimental management system, consisting of establishing and generator able to produce 33 g/h, at a concentration maintaining a policy with a commitment and strict of 1.8 per cent ozone, in contrast to the capacity ori- adherence to environmental conservation; develo- ginally manufactured by Qualidor of 7g/h and a ping a plan taking into account all the aspects of the concentration of 1.2 per cent. Another important organization and current legislation; implementing characteristic achieved by the equipment built is its a program to attain the plan’s targets and goals; esta- continuous operation for long periods, in principle, blishing procedures to monitor the organization’s for more than a week. Based on these results, the fol- environmental performance and its compliance with lowing work will carried out in the Second Stage: the established policy. development of peripheral equipment to ensure proper and reliable working of the generator for each type of application chosen for the project, with Development of a High emphasis on automation, including a digital control 66 Performance Ozone Generator system of its various operational functions, coupled to a microprocessor control system; construction of Coordinator: generators to meet demand in terms of carrying out Wilfredo Milquiades Irrazabal Urruchi in situ experiments; improvement of fixed laborato-

Translating Research into Business • 101 ries (ITA and Unimep) for monitoring and qualif- frastructure and installations, lowering the cost and ying the generators to be constructed and the mate- improving the control of irradiated gems. rials to be handled by them; and the implementati- on of a mobile laboratory station for the analysis of ozone and humidity content, to appraise the wor- Experimental Bench king of the generator over time, and properly to col- 68 for Ratifying lect samples of the materials treated with ozone pro- Software and Hardware duced by the generator. for Intelligent Batteries

Coordinator: Improvement in the Gilberto Janólio Quality of Precious Stones 67 Company: through Microbiological DCSYSTEM Energia e Telecomunicações Purification and Induction of Color through Ionizing Radiation Approved value: Phase 1: R$ 49,600 Coordinator: Phase 2: R$ 60,200 Etsuko Ikeda de Carvalho The purpose of the present piece of research is to Company: develop an experimental bench for ratifying softwa- TRON Tec Radion Tecnologia da re used in sizing and studying the dynamic behavior Radiação Ionizante Comercial Ltda. of lead acid and special batteries. With this bench Approved value: and the validation of the software, it will be possible Phase 1: R$ 35,400 to develop methods and tools for the diagnosis and prevention of operational conditions, and the useful The Brazilian precious stone market is worth life of systems using direct current essential to the millions of Reals and in general they are channeled performance of equipment used in telecommunica- abroad through the export of crude stones at very tions companies. These include fixed and mobile low prices; then, after being treated in various ways, phone switchboards and biomedical products, such they are re-imported. Generally speaking, this treat- as organs for transplant. The adaptation of this soft- ment adds value of up to ten times the original va- ware to a suitably integrated and validated piece of lue of the stone. In terms of economically impor- hardware will enable the development of this pro- tant Brazilian precious stones, emeralds stand out ject. Another of its goals is to ascertain, with a high for their beauty and popularity yet they are marked degree of accuracy, the capacity of the direct current by the presence of contaminants in their crevices system, especially in completely sealed batteries containing iron and sulfur. A number of published which allow no access for developing diagnostic and papers have indicated that certain bacteria of the preventive maintenance and, also, fully implantable Thiobacillus genus are able to attack rocky structu- batteries that similarly have no access faculties for res, chiefly concrete, and remove the iron and sulfur, diagnosis and maintenance. This adaptation is ex- leading to the formation of acids that deteriorate pected to give rise to “Software and Hardware for In- these structures. The present project intends to take telligent Batteries”. advantage of the microbiological method, through use of species of the Thiobacillus genus, to purify Brazilian gems, chiefly emeralds, the contamination Anodic Oxidation of which is related to the presence of sulfur and 69 with Aluminum Plasma in iron, in order to add value to the stones and decre- an Aqueous Medium ase Brazil’s expenditure of foreign currency. Simi- larly, a treatment widely practiced abroad for obtai- Coordinator: ning topazes, tourmalines and other colored Gerhard Ett gemstones, using ionizing radiation, is little used in Company: Brazil, to such an extent that stones are sent abroad Anod-arc Serviços e Comércio Ltda. for treatment, later to be re-purchased by Brazilian jewelers. The present proposal intends to make it Approved value: possible to treat precious stones using Brazilian in- Phase 1: R$ 67,566.20

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This project seeks to obtain compact aluminum formation transmitted by the landmark stations dis- oxide layers with a hardness similar to corundum tributed along the routes. At the end of the day, or at (2300 Hv), through anodic plasma oxidation, in wa- any other time, the recorders in the vehicle downlo- ter, of aluminum, other reactive metals, and their al- ad the information stored at collecting stations. The- loys. Both the process and the layers obtained bear se stations are connected to a central computer to little resemblance to the traditional process of hard process the information and produce reports. The oxidation (maximum 700 Hv 0.5 N). The proposers recorders are carried on each vehicle in the fleet and intend to develop the process and optimize the para- they consist of a radio transponder, an antenna and meters according to the costs and properties of the a control board. The transmitters are fixed, distribu- layer obtained. Differences in the coefficients of ted along the bus routes, installed on posts or next to thermal expansion in use and thermal cycling can be traffic lights and they consist of a transponder, an corrected by including additional oxide. The relati- antenna and a control board. In Stage 1, a prototype vely low hardness of the layers obtained by hard ano- of the system, consisting of a collecting station, a dization can be explained by their dentiform struc- transmitter, and two recorders, was built. The feasi- ture. It is not proportional to their resistance to wear bility of the system was checked and the project but is confined to the large number of uses where team was able to deal with various aspects related to abrasive grains (or the shape of the contact pieces) its implementation. The purpose of Stage 2 is to enable high punctiform pressure. The structure of carry on the work, completing solutions to the main the layers obtained by the new process will not suf- questions relating to the construction of the moni- fer from this restriction. toring system and the development of prototypes of the system’s equipment.

System for Monitoring 70 Urban Public Program Transport Vehicle Fleets 71 Decompressing System for Risc Processor Coordinator: Claudemir Marcos da Silva Coordinator: Silvio Luis Lima Nogueira Company: Neuron Engenharia and Comércio Company: de Equipamentos Eletrônicos Ltda. IDEA! Sistemas Eletrônicos Ltda. Approved value: Approved value: Phase 1: R$ 38,047.45 Phase 1: R$ 41,300 Phase 2: R$ 130,000 / US$ 2,000 The purpose of this work is to develop a compu- The project aims to establish of a System for Mo- ter program decompressing system for Risc proces- nitoring Urban Public Transport Vehicle Fleets de- sors. The central idea of this approach is to encode signed to monitor the punctuality of buses or vans expression trees and operand sequences separately through the use of radio signals along pre-establis- using Huffman coding. Decompressing the program hed routes. Besides informing the moment when is done using a decompression module based on dic- each vehicle passes by the radio devices, the system tionaries. The growth of the market for dedicated can also monitor other parameters, such as, for systems (embedded systems) has led to the emergen- example, the speed of the vehicle and the number of ce of a project method known as System-On-a-Chip passengers carried. The information collected from (SOC), where a processor, integrated with memori- the vehicle is transferred by radio to a collecting sta- es, DMAs, I/T ports, and other modules, is designed tion coupled to a central computer by radio or a te- to minimize the cost of the system. One of the most lephone line. This computer processes the informa- difficult tasks in an SOC is to make the application tion received to help assess the system’s punctuality, program fit within the specified area of silicon (mi- the distances covered, the number of vehicles in ope- croprocessor). This problem is particularly critical ration, costs, speed control, etc. It also enables the for industry. IDEA! Sistemas Eletrônicos has colla- municipal authorities to monitor the service quality. borated on research into the compression of pro- Under the proposed scheme, each vehicle will be fit- grams on SOCs developed by Prof. Guido Araújo ted with a recorder able to receive and store the in- and his doctoral students at IC-Unicamp. The idea

Translating Research into Business • 103 consists of storing the compressed code in on-chip Call IP – Telephone memory, decompressing it online during the search 73 Switching System for Call for instructions. The commercial feasibility of this Centers Using Voice Over IP proposal was recently demonstrated by the launch by IBM of a PowerPC (CodePack) processor with si- Coordinator: milar but fewer features. Research into this project Tereza Cristina Melo de Brito Carvalho has already reached the point where the results Company: achieved encourage its commercial sale. The final Macrolog Teleinformática Ltda. objective of this proposal is to implement a decom- pressing system to be sold as core software in IP (In- Approved value: tellectual Property) providers. Phase 1: R$ 44,920

Macrolog Teleinformática Ltda. has a new project Development of an for the research, development and implementation of 72 STM-1 Multiplexer for Optical switching systems for call centers using VOIP – Voice Access Networks Over Internet Protocol, instead of the traditional switchboards with (ACD) Automatic Call Distribu- Coordinator: tors and CTI (Computer & Telephony Integration) Rege Romeu Scarabucci interfaces. This new technology is made possible by the constant increase in the performance of net- Company: works, as well as by the progress of voice compressi- Asga Microeletrônica S/A on technology. Nowadays, networks enable speeds Approved value: higher than 100 Mb/s and silence compression and Phase 1: R$ 26,300 suppression algorithms that compress voice messages Phase 2: R$ 200,000 to 8 kb/s. With these figures, networks can transmit voice information, as well as other data, with high The purpose of this proposal is to carry out a fe- quality. With the development of a device for mana- asibility study for developing an STM-1 multiplexer ging this telephone traffic which we can call a “Call with the capacity to carry up to 63 E1 tributaries at Manager”,it is possible to switch virtually all voice in- 2048 kb/s for optical access by large users to the pu- formation at existing points in the network without blic telecommunications networks. The technology the need for a parallel telephone network and a spe- to be used is the Synchronous Network, developed cific telephone switchboard. Within the proposed in recent years and standardized by the International operating area, the use of “virtual switching” by IP Telecommunications Union (ITU) as SDH – will enable a new level of call centers to be created, in- Synchronous Digital Hierarch. Synchronous Net- troducing countless benefits to users, such as: facili- work Multiplexers are the best communications sig- tating the connection of multimedia calls, integrating nal carriers known. They were developed to carry voice, video, web, e-mail and fax; cost will be lowered; everything from low-speed digital signals in their savings will be made through lower rates for long- small containers to very fast data signals, used, for distance calls and it will also open up the high tech- example, in supercomputers. The all-encompassing nology market to small call centers. supervision process adopted in the Synchronous Network, with information available on the status of the communication, in failures and on performance Ceramix – Computer System – as well as enabling centralized management – is ra- 74 for the Formulation and dically transforming the quality of public communi- Reformulation of Ceramic Paste cations networks. The feasibility study for the deve- lopment of the first Brazilian SDH multiplex Coordinator: equipment will consist of the following: a study of Edélcio Leme de Almeida the performance of the chipset recently launched on Company: the world market; a systemic project for two types of SpAll – Sistemas de Informações Ltda. multiplexer, a MUX Terminal and a MUX ADM (Add-Drop Multiplex), and planning the stages of Approved value: the project. It is designed to provide a detailed esti- Phase 1: R$ 31,440 mate of the time and cost involved. Phase 2: R$ 65,920

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The purpose of this project is to develop a new shell (around R$ 79 million in 1996), and the obser- piece of software using Artificial Intelligence techni- vation that part of the cause of this problem could ques to make it easier to manufacture ceramics in be connected not just to age, nutrition, genetics, or this country, taking into account that the main pro- the environment, but also to the health of the birds perties of the sector’s raw materials (chemical and – involving specific pathologies, including alteration mineralogical composition, particle size and the ca- to the metabolism of intra-medullar calcium, caused tion exchange capacity) are always unique; there are by unknown or little-studied infectious agents – Li- no two that are identical in nature. When one of vet Produtos Veterinários has begun a microbiologi- them must be replaced, all the ceramic paste has to cal study of the bone marrow of the femur, tibia and be reformulated, an extremely complex task in the metatarsus of birds with altered egg-shell quality. As manufacturing process. This software will run under a result, it was observed that the change in the calci- Windows 9X and NT, because of their large installed fication of the bone marrow and consequent malfor- base. The composition of traditional ceramic pro- mation of the egg-shell may be related to the bacte- ducts (tiles, porcelain, chinaware, etc.) involves rial etiology including its respective toxins. Field countless natural raw materials, such as clays, kaolin, experiments have enabled the identification of bac- feldspar, talc, and quartz. What we propose is to wri- teria such as S. epidermides, S. aureus, Haemophylus te a new piece of software using an advanced GUI, to sp., Streptococcus sp., E. coli and Bacilus sp. in the carry out the same basic functions as Reformix, but birds’ bone marrow without creating a problem for with countless implementations. The use of Artifici- the egg-shells in the same breeding stock and the al Intelligence techniques to create a database will preparation of an experimental vaccine based only make it possible to include a Wizard in the software on the S. aureus. Vaccinated and non-vaccinated to help users to identify errors in product formulati- birds show a relationship between the presence of ons and in the choice of raw materials. An initial the bacteria and the re-absorption of calcium into study will be carried out of the various computer the bone marrow. implementations of the Simplex algorithm, to check which implementation will be the most efficient in this particular case. The programming language The Use of Molecular chosen is Delphi, in conjunction with the Paradox 76 Techniques in Farming: database handler. Improvement of the Genealogical Recording of Cattle and Horses Development of a 75 Bacterial-Toxoid Vaccine to Coordinator: Prevent the Poor Egg-Shell Quality Cynthia Rachid Bydlowski Syndrome in Breeder Birds Company: and Commercial Laying Hens Linkgen Biotecnologia Veterinária e Agropecuária S/C Ltda. Coordinator: Masaio Mizuno Ishizuka Approved value: Phase 1: R$ 20,000 / US$ 24,283.20 Company: Phase 2: R$ 0 / US$ 94,282 Livet Produtos Veterinários Ltda. Approved value: The purpose of this project is to standardize the Phase 1: R$ 51,274.50 / US$ 0 analysis of micro-satellite DNA regions in cattle and Phase 2: R$ 17,550 / US$ 17,211 horses, so as to enable both checking paternity and maternity as well as helping to identify the animal by The present piece of research is intended to con- means of genotyping, in order to complete the gene- tinue the study of the poor egg-shell quality of bree- alogical records. At present, few genealogical recor- der birds, and, in particular, commercial layers in ding services in Brazilian breeding associations use Brazil, in order to develop a bacterial toxoid vaccine the technique of typing blood groups to check the to prevent or minimize this problem (stages 1 and 2, validity of their records of animals. This technique respectively, of the action plan). In the light of the has problems that can be overcome by the analysis of substantial economic losses in Brazilian poultry rai- micro-satellite DNA regions. Improving the recor- sing, deriving from the poor development of the egg ding system will enhance the organization and add

Translating Research into Business • 105 value to the different breeds in Brazil. At this stage of yers is essential to scientific studies requiring a sur- the project, it is intended to identify polymorphisms vey of the local control of experimental areas and it in the hyper-variable micro-satellite DNA regions of will contribute to determining the physical state of cattle and horses using the PCR (Polymerase Chain the soil, both in pedological studies and in those de- Reaction) technique. The DNA was prepared from signed to assess the machine-soil-plant relationship. the blood cells and/or hair follicles of the animals The initial prototype of the equipment uses a cell and the polymerase chain reactions were carried out with an extensometric load as a sensor of the pene- using different pairs of specific oligonucleotide initi- tration strength. An electronic ultrasound type sen- ators for the micro-satellite regions. Through these sor is used to measure the depth of penetration. The studies it is intended to characterize the individua- geo-referenced position, furnished by a Global lity of animals of the same breed, whether or not re- Positioning Systems (GPS), is read through a serial lated. To examine the polymorphisms of the expan- interface. This same interface is used to transfer the ded fragments, a system of electrophoresis in data from the penetrometer to a PC. This has non- polyacrylamide gels and coloring with silver nitrate volatile memory enabling storage of the data and an was employed. alpha-numeric display used to configure and opera- te the equipment and to view the results.

Development of a 77 Low-cost, Geo-referenced, Study of the Process Electronic Penetrometer 78 of Freezing Bread Coordinator: Coordinator: Nelson Luis Capelli Carmen Cecília Tadini Company: Company: DLG Automação Industrial Ltda. FMAIIS Indústria de Alimentos Ltda. Approved value: Approved value: Phase 1: R$ 24,910 Phase 1: R$ 23,400 / US$ 10,581 Phase 2: R$ 147,360 Phase 2: R$ 58,082 / US$ 32,566.19

In the first stage of the project a technical and The purpose of this research project is to place financial feasibility study was undertaken for the on the market an alternative frozen product, to manufacture of a low-cost, geo-referenced, electro- meet, in particular, the heavy demand from conveni- nic penetrometer. An initial prototype was built ence stores, including supermarkets and highway for the main purpose of identifying potential tech- stores. The research will be designed to shed light on nological and financial difficulties. The function of the knowledge of the technology involved in the va- the proposed equipment is to determine the cone rious stages of producing bread for freezing, in par- index (resistance of the soil to penetration), as a ticular, the parameters of the process during fermen- function of the depth of penetration and geo-refe- tation and pre-baking, and surveying the freezing renced position of the equipment. This electronic curves, as well as the optimal distribution and stora- penetrometer will enable data to be obtained swift- ge conditions, in order to appraise the enterprise’s ly, accurately and at a low operating cost, for the profitability. The manufacture of bread has been au- preparation of geo-referenced maps of layers of tomated and improved over the years. Brazil still has compacted soil. The construction of the initial pro- market potential for products in the dough and bre- totype showed the technical feasibility of develo- ad sector (other than the cakes segment), since it has ping a commercial product. Pilot equipment will be low annual average consumption. Specifically regar- developed to be assigned, by way of demonstration, ding industrialized bread, the segment has been gro- to research institutions and companies interested wing in production volume and variety. Production and qualified, in order to subject it to normal use and freezing of the bread involves problems such as and thus identify any weak points. It is also propo- maintaining the properties of the yeast and its fer- sed to achieve a finished product intended for sale menting capacity, maintaining the physical properti- by the company associated with the project. The de- es of the dough and its ability to retain carbon dio- termination of the occurrence of compacted soil la- xide over the shelf life of the product.

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Optical System for Approved value: the Automatic Positioning Phase 1: R$ 30,500 79 of Screens (Sopat) Phase 2: R$ 55,940 / US$ 99,979.30

Coordinator: The present research project is intended to deve- Benedito Carlos da Silva lop local carbonaceous materials to be used in the manufacture of lithium ion batteries, a product Company: made up of two electrodes that intersperse lithium Akros Engenharia e Empreendimentos Ltda. ions in organic and lithium salt electrodes. The main Approved value: materials used as cathodes are lithium oxides of the Phase 1: R$ 16,280 type: LiMn2O4; LiCoO2 and LiNiO2. And, the main Phase 2: R$ 156,400 materials used as anodes are made up of carbonace- ous compounds with a graphitic structure. At pre- The present piece of research is intended to deve- sent, the main uses for lithium ion batteries are lop an Optical System for the Automatic Positioning electronic devices in general, in particular mobile of Screens (Sopat), the purpose of which is to arrive phones and portable computers. The main features at a definitive solution for a problem faced by manu- of these batteries are: high reversible capacity facturers of flat paper, which causes considerable fi- (mAh/g), high power density (Wh/kg) and long life nancial loss. This problem occurs in paper producti- cycles. The main materials to be studied are: natural on, giving rise not only to damage, but also, and in graphite, carbon fiber, sugar and sugarcane residues particular, causing production stalls for maintenan- (bagasse), and coffee beans. These materials have ce, with the resultant decline in productivity. At the shown great potential for use in lithium ion batteri- beginning of the paper manufacturing cycle there is es. The main properties that the carbonaceous mate- a piece of equipment that undertakes pre-drying of rials must have, in this case, are: high reversing capa- the pulp paste. This equipment consists of large city for interspersing lithium and being good cylinders, beneath a synthetic fiber screen which electricity conductors. The main goal of phase 1 was supports the paste. When stretched, it revolves the to obtain a material with a higher capacity at low cylinders at a speed of up to 1,000 m/min. As the cost. During phase 2, the materials that proved the surface of the cylinders is flat, there is a need for an most promising were submitted to thermal and che- active control of the position of the screen over the mical treatment to optimize their crystal structure. cylinder, which, under normal conditions, has a ten- dency to shift to one side. The solution used at pre- sent is a mechanical system, which has worked, but 5th BIDDING INSTRUCTIONS with reservations. To make matters worse, the envi- ronment in question is subject to temperatures of around 120°C, with high humidity and chemical ste- Pre-Distortion Linearizer am. Sopat intends to solve the problem of the posi- 81 for High Power Amplifiers tioning of the screen through the use of optical sen- for Land-based Satellite Stations sors, employing bundle type optical fiber to enable information to be sent and received without tou- Coordinator: ching the equipment, which is immune to environ- Wilton José Fleming mental conditions and will be installed together with Company: a micro-controller outside the equipment. Beta Telecom Consultoria e Comércio Ltda. Approved value: Development of Advanced Phase 1: R$ 27,600 / US$ 12,400 80 Materials for Lithium-Ion Battery Electrodes The present work is designed to investigate the so-called pre-distortion linearizers, used in satellite Coordinator: communication systems. Initially, a solution for C- Antonio César Ferreira/ José Alberto band satellite communication will be investigated, Rodrigues Ferrão and subsequently, the possibility of using it in Ku- band will be assessed. The pre-distortion linearizer Company: creates a transfer function, which is opposed, from UniTech Ltda.

Translating Research into Business • 107 the standpoint of distortion, to that of the amplifier tic granite is a material made of natural crushed sto- to be linearized. Among its main characteristics are ne. As a structural material, synthetic granite has ex- broadband operation and the ability to operate re- cellent mechanical properties, such as: long-lasting gardless of internal alterations to the amplifier. De- mechanical stability, internal damping about eight velopment of the technology of digital modulation times greater than traditional materials, a high de- and compression circuits enables (and even de- gree of thermal stability, geometric flexibility and mands) that various carriers be transmitted in the the ability to use metal grafts. We will be developing same waveband previously occupied by a single car- a process to mold the microscope’s structural sys- rier in satellite communications systems. The linear tem in synthetic granite. The process and the opti- nature of the amplifiers is a predominant factor in mization of the molding will enable high quality avoiding interference with these signals and services. parts to be produced on a large scale. Setting up the In satellite communication technology, the use of entire production process for parts in synthetic gra- special valves is required. In this case, depending on nite, we will add the other optical and mechanical the desired transmission power, there is no similar components so as to achieve a very high quality, but solid state valve, or when it exists (for low power), it low-cost microscope. In this way we, we hope to do- is very high-priced. To solve the problem of the line- minate the domestic market and compete in the ex- ar structure, manufacturers have adopted the system port market. of making the power amplifiers (HPAs) run at subs- tantially below their maximum power output. This condition is called back-off and, although techni- Development of a cally correct, its cost is high. The solution to this type 83 User Terminal for of problem is to introduce a linearizer, the purpose Transmitting and Receiving of which is to compensate for the intrinsic non-line- Voice and Data by Satellite ar nature of the HPA gain and phase. Coordinator: Joel Muniz Bezerra Optical Precision Company: Microscope with 82 Databus Sankay Ltda. Synthetic Granite Base Approved value: Coordinator: Phase 1: R$ 25,900 / US$ 11,100 Fernando de Moraes Mendonça Ribeiro Phase 2: R$ 164,700 / US$ 45,925 Company: The purpose of this project is to develop a semi- MM Optics Ltda. fixed voice and data terminal for remote areas and Approved value: a truck locator for fleet monitoring by satellite. At Phase 1: R$ 45,420 the end of 2001, the ICO satellite communication system will come on commercial stream, using a MM Optics is a new company, but firmly com- constellation of 12 medium orbit satellites. Users of mitted to participating in and promoting technolo- this system will then be able to send and receive gical Brazilian innovation in the field of optics. It is voice and data signals through fixed or mobile ter- a small company that is making every effort to pro- minals from anywhere on earth. The ICO group duce three models of microscope (MM 1600, high considers Brazil to be one of the three largest mar- precision, binocular up to 1600x, MM-01 didactic kets for this system, particularly, in serving users in up to 600x, MM- L1 expansion of up to 30x for use remote areas and in monitoring freight trucks. Sin- in agriculture and teaching applications) and coun- ce Anatel will require present fixed-line telephone tless other precision systems. With this experience suppliers to provide a service for areas of low popu- and having already taken part in a development lation density, the ICO expects its system to be a fi- project in the microscopy field with IFSC-USP and nancially feasible option for these operators. In Lamafe-EESC, both of USP in São Carlos, MM Op- phase 1 of this project, the terminal architecture tics proposes to develop and produce an innovative was defined, the antenna project was carried out, microscope, in which its structural part is made of and the RF front-end was built and prototypes of synthetic granite, improving its stability, lowering these subsets were assessed. Contact was also esta- costs, and thus making it more competitive. Synthe- blished with component suppliers and potential

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customers and distributors for the above mentio- Company: ned equipment. For phase 2, the finishing of the Arboreto Produtos Florestais Ltda. front-end project and the antennas is planned in Approved value: order to compact and fully meet the specifications, Phase 1: R$ 41,900 / US$ 700 the software and hardware development of the ter- minal, including the telephone and fax interfaces, The Tree Physiology Laboratory (Department of definition of the terminal manufacturing procedu- Forestry Sciences - Esalq/USP) is part of the Thema- res and tools and the ratification of the equipment tic Clonal Silviculture and Forestry Vivaria Program. with the ITU, ICO, and Anatel. This program has been undertaking basic research, technological development and the transfer of clo- ning technology, as well as assessment of the politi- Ink Jet cal, environmental, social, and legal risks of using Space-Time Recorder 84 this technique and improved raising and use of fi- nancial resources. Coupled with research, there is Coordinator: personnel training and technology transfer in the Yoshikazo Ernesto Nagai production of clones of forestial essences, chiefly Eu- Company: calyptus and Pine, for companies associated with the Optron Micromecânica Óptica Ltda. – ME Forestry Studies and Research Institute (IPEF), other companies, producers, and research institutes, such Approved value: as Embrapa, with species of bromeliads, orchids, ba- Phase 1: R$ 9,500 nana, cashew, bamboo, rubber tree, teak, and the Phase 2: R$ 35,900 cryptomeria. The research group’s main fields of operation are the handling of macro, mini and mi- The present research project is intended to deve- cro- clonal gardens, the handling of the production lop an alternative to the high-voltage sparker used in of eucalyptus seedlings, partnerships in the produc- classical mechanics experiments: a space-time recor- tion of micro-propagated seedlings, environmental der based on the same principle and the head of an stress studies in cloning; partnerships in research ink-jet printer with a piezoelectric element. Classical with equipment and supplies companies for foresti- mechanics experiments in schools and universities, al vivaria; in vitro mineral nutrition, in vivaria and when offered, are generally trivial and with concep- in the field: clone selection; somatic embryo-genesis tually poor content, in contrast to the elegance with of eucalyptus, the production of micro-propagated which the theory approaches and solves teaching seedlings of clones of Eucalyptus spp., Pinus spp., teak problems, making use of conservation laws such as and other species of forestial interest. linear moment. Nonetheless, for direct proof of such straightforward laws as these, equipment is required. Tracks and air tables minimize the effect of attrition, Low-Cost maintaining a fine layer of compressed air between Solar Heater the moving part and the surface over which it slides. 86 Furthermore, they are equipped with high-voltage Coordinator: space-time recorders leaving fine black dots on wa- Julio Roberto Bartoli xed paper (or fax paper) over the trajectory and pe- riodically over time. A dangerous inconvenience of Company: this type of apparatus is the high voltage present SunPower Engenharia Ltda. throughout its length. Fed by common batteries, the Approved value: space-time recorder here planned could be built in Phase 1: R$ 33,989 to the moving part, thus avoiding any impediment to the movement. The rest of the equipment would The purpose of this project is to offer a low-cost be the same as the conventional track or air table. solar heater able to heat sufficient bath water for a family of four, the final cost of which, with accesso- Development of Natural ries and components, does not exceed R$ 100. The Christmas Trees for Brazil result of nine years of feasibility studies and analy- 85 ses, it began soon after Sunpower Energia Solar Ltda. Coordinator: began operating. At the time of the Earth Summit Antonio Natal Gonçalves 92, the first prototype of the solar heater was built to

Translating Research into Business • 109 take part in the event’s companies exhibition. It was on will have to be to world standard SOT115J2. The based on welded PVC film, the body in waterproof, third stage provides for the establishment, develop- corrugated cardboard, covered to produce the gree- ment and the design project for setting up the tes- nhouse effect in the collector (using film employed ting of the component. Finally, in the 4th stage, the in flower greenhouses), and a water tank based on a qualification testing will be carried out. polystyrene box. The concept was presented to Se- brae and immediately approved. Now, it is ready to be approved by an ideas and technological compani- Optimization of the Process es incubator, under the auspices of USP, Ipen and 88 of Vulcanization of Retainers IPT. The team is willing to disclose the basic con- through Microwaves and cepts of the project for public discussion. Compound Material Molds

Coordinator: Hybrid, Broadband, High-Gain Antonio Carlos Alvarez Fasano Amplifier Module, Using Hybrid 87 Company: Copper Plating Technology OmniTek Tecnologia Ltda. in an Alumina Substratum Approved value: Coordinator: Phase 1: R$ 48,776 Alexandre Nunes da Trindade This project is designed to develop a process of Company: vulcanization of retainers through microwaves and Proqualit Montagem e Comércio Ltda. molds in compound materials, in accordance with Approved value: the subject of a doctoral thesis. Work already carried Phase 1: R$ 33,296 out includes the study of the behavior of polymers and plastics to be used at industrial level microwave The project consists of developing and cons- frequency (2.45 GHz), by placing pieces of material tructing an electronic component called a Hybrid with wavelength guide ends (this stage was carried Amplifier Module (MHA). This component is used out jointly between OmniTek and the microwave la- inside amplifiers used in Cable TV (CATV) Systems boratory of the Polytechnic School), and simulation and Collective VHF/UHF and “C” Band Systems. of the behavior of the system in finite electromagne- Another important application is its use in Two- tic 3D elements (this stage was also carried out with Way amplifiers using two communication channels. the participation of OmniTek). The new stages in- These amplifiers enable amplification of TV signals clude the theoretical sizing of the wavelength guides in one direction and data amplification, making and sounding chamber, the design of the part to be possible Home Banking, Home Shopping and Inter- manufactured and the mold in polymeric PEEK ma- net services in broadband networks in CATV sys- terial plus 30 per cent carbon fiber and the establis- tems. The first phase will be to undertake the elec- hment and study of method of injecting elastomers trical design project for an amplifier in the that are more appropriate to the project in question. push-pull and cascode configurations, in order to It also includes the manufacture of an injector set obtain a circuit with broadband characteristics (40- and chamber supports to be installed in commercial 860MHz), high gain (34dB), a low noise ratio injectors, injection and vulcanization testing and (<8dB), low distortion, solid construction, high re- improvement of the process parameters. liability and a high degree of repeatability for large- scale production. To succeed, the components will have to be modeled to optimize the circuit and the Automatic Reconfigurable simulations. In this stage, Proqualit will be helped 89 System for Testing by the CPqD – Telecommunications Research and Electronic Modules Development Foundation’s laboratory. The 2nd phase consists of the manufacturing of the prototypes em- Coordinator: ploying alumina layers coated with metal through a Gilberto Antonio Possa Cooper Plating process. This stage will also involve Company: the milling of the steel bases on which the layers will Qualibrás Assistência Técnica be deposited, as will the covering. The encapsulati- Dirigida e Comércio Ltda.

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Approved value: indicating the amount of reworking and its influen- Phase 1: R$ 50,001 ce on the mechanical properties of the material (re- Phase 2: R$ 278,705 sistance to metal fatigue along with changes to the microstructure because of reworking the welds). In- This project involves the development of an auto- formation may result from this project to support matic reconfigurable system for testing electronic the preparation of a guideline on the quality of the modules to be used initially in testing and repairing number of welds that can be reworked in the sector the terminal boards of digital telephone switchboards and still ensure the same level of safety of the equip- produced by various manufacturers in Brazil. These ment. During flight, an aircraft is subject to repeated boards interface with subscribers, public telephones, loads of highly varying size and frequency. It is esti- and with switchboards and devices. The objective is to mated that 90 per cent of failures, in service, of com- develop an initial product that will be used in most ponents that undergo movement of one sort or ano- commonly used digital telephone switchboards mo- ther, can be attributed to material fatigue. The dules. The system will be flexible – in other words, its aircraft engine cradle is a critical aeronautical com- hardware and software must be reconfigurable to ena- ponent that undergoes complex loads, and fractures ble more than one technology’s or manufacturer’s caused by fatigue are constantly found. This compo- modules to be tested; it must be of low cost in imple- nent, manufactured in ABNT 4130 steel, includes mentation and reconfiguration; it will be efficient and welding operations during manufacturing , or even fast in the tests; and have a database to store informa- reworking, and the process requires considerable tion on the failures and repairs of each board tested to analysis and care. A study of fractures in aircraft en- be used for trouble-shooting, making repair services gine cradles suggests that the welds are the parts easier. Experience suggests that terminal modules are most subject to metal fatigue failure. For this reason, those with the highest priority (subscribers, public te- the standards in respect of the manufacture of these lephones, connections, etc.). It is estimated that there components are extremely strict and careful, parti- are around a million of these modules in Brazil. The cularly in the case of welding operations, where a failure rate is estimated around 20 per cent a year and zero failure rate is demanded. What we do not have, the average repair cost is R$ 200 per module, and the however, are guidelines on the number of rewor- estimated revenues from repairs are only R$ 40 milli- kings permitted and their consequent influence on on a year. The services of the PqD’s Microelectronics the fatigue of the joint. Division will be contracted. This development will also enable Qualibrás to qualify for the supply of tes- ting and repair services to large manufacturers of te- Solar Collector lecommunications equipment. The demand for these 91 Manufacturing Process services is growing fast. Coordinator: Mauro Hirdes Reworking Welded Tubular Company: Aeronautical Structures - 90 Nova Aliança Comércio Indústria de Steel ABNT (Brazilian Association Sistemas Solares e Produtos Afins Ltda. of Technical Rules) 4130 Approved value: Coordinator: Phase 1 + Grants: R$ 79,385.23 Herman Jacobus Cornelis Voorwald Phase 2 + Grants: R$ 231,935.20 / US$ 1,000 Company: During the first half of 2000, the company No- ESRA Engenharia Serviços e vaAliança (formerly Dynamikarman) and the engi- Representação Aeronáutica Ltda. neer Mauro Hirdes, the project coordinator, develo- Approved value: ped a new process for manufacturing solar collectors Phase 1: R$ 39,318 for heating water. Thus, they arrived at a process proposal based on brazing and on changing the pa- The purpose of the present project is to establish nel material to copper. Because of its innovative na- parameters for reworking welded tubes in ABNT ture, it was decided to submit a financing project to (Brazilian Association of Technical Rules) 4130 steel develop it to FAPESP. The purpose of the original used in the manufacturing of aircraft engine cradles, project was to enable the construction of a new type

Translating Research into Business • 111 of high-efficiency collector, known as “Cellular”,and Program. In the first stage of this program we sought it had undergone corrosion and supply problems in to show that optimization in structural projects carri- its original design concept – aluminum roll-bond ed out with more solid optimization algorithms, such panel. The collector, unconventional in its construc- as DOT and Faipa, together with MSC/Nastran for tion, has a capture panel made of two sheets shaped modeling and analyzing structures by finite elements, and welded to each other so as to form channels are more efficient and lead to better results than the along which water can flow. The interconnection problems solved with the algorithms available in the between these channels, in a network similar to a he- MSC/Nastran optimization modules. xagonal beehive, makes the panel highly efficient at capturing solar rays. Impressing with elastomer and spot welding was employed as the manufacturing Pulsing Current process, and copper was chosen as the basic materi- 93 and Squared Wavelength al to avoid problems with corrosion and to increase Rectifier for the efficiency of capturing the rays of the sun. A co- Anodizing Aluminum operation agreement was arranged with the Materi- als Characterization and Development Center – Coordinator: CCDM, of São Carlos Federal University, to provide Elisabete Jorge Pessine technological support for the project. Company: Termocontroles Indústria e Comércio Ltda. Development Approved value: 92 of a Tool for Phase 1: R$ 49,806 Optimizing Structures The technological innovation proposed here, to Coordinators: be developed jointly by Termocontroles and Uni- Susana Angélica Falco Meira / camp-Ipen (São Paulo State University - Campinas Wolodymir Boruszewlski and the Institute of Nuclear and Energy Research), consists of the manufacturing of a pulsing current Company: and high-power, squared wavelength rectifier ap- Fibraforte Engenharia propriate to the hard anodization process to be used Indústria e Comércio Ltda. on an industrial scale. Anodization is one of the best Approved value: methods of giving aluminum a protective coating. Phase 1: R$ 38,400 / US$ 6,000 The hard anodization process permits thicker coa- Phase 2: R$ 101,200 / US$ 65,000 ting than the conventional ones. However, they are restricted by the composition of the aluminum al- The purpose of this program is to develop infor- loys, by the temperature and by their degree of bur- mation technology procedures and tools that are ning. High temperatures encourage the formation more efficient and have broader coverage to optimize of an external soft and porous anodic layer, redu- structures, using MSC/Nastran to model and analyze cing resistance to wear and significantly limiting the structures and the Faipa and DOT software programs increase in thickness. The advantages of anodizing for optimization. In practical optimization applicati- aluminum alloys carried out using squared wave- ons for the structure of satellites, carried out at Inpe, length pulsing current rectifiers, compared with it was observed that the optimization algorithms avai- processes using only continuous current, range lable in the MSC/Nastran structure analysis software from a saving of 25 per cent in use of reagents, in- were not very efficient from the standpoint of conver- cluding the achievement of thicker layers (50 - 700 gence and arriving at the global optimum. There are µm) faster, whilst obtaining a coating which is more general purpose software programs available that of- resistant to corrosion and abrasion, since the layer is fer more powerful and efficient optimization algo- generally more homogeneous and less porous, wi- rithms. One of them is DOT – Design Optimization thout burning. In hard anodization of large alumi- Tools, sold commercially by Vanderplaats Research num parts the rectifier needs to be high powered, and Development. Another software program availa- since the Al2O3 film is an electrical insulator. The ble is Faipa – Feasible Arc Interior Point Algorithm, feasibility of constructing a prototype will be esta- developed under Coppe’s Mechanical Engineering blished in the laboratory.

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Improvement of the Surface The proposed research project is intended to 94 Properties of Industrial Components qualify the company in generating DEM-Digital Ele- through Three-dimensional vation Models, through orbital radar images, to sup- Ionics Implementation port the preparation of topographical maps and SAR (Radar) Integrated Products for geo-environ- Coordinator: mental application. The method is based on radar Raul Murete de Castro measurement using Standard and Fine images from the Canadian Radarsat-1 satellite. The proposal gives Company: priority, too, to introducing a culture of using radar Metrolab Engenharia Ltda. imaging technology in the company. Brazil is of con- Approved value: tinental size but has poor cartographic knowledge. Phase 1: R$ 36,020 / US$ 6,900 Only 60 per cent of the country has been topogra- Phase 2: R$ 57,220 / US$ 114,414.75 phically mapped on a scale of 1:100.000 and most of this is out-of-date. In this context, the use of SAR In- Having achieved significant results in an experi- tegrated Products has great added-value potential, ment involving ionic implementation by immersion but it depends on strict geometrical correction (or- in plasma (IIIP), the use of this method is now being thorectification) of the images. The project focuses tested in some companies in the State. Ionic imple- on generating DEMs of a test area in the Serra dos mentation (II) is a method of surface treatment with Carajás (State of Pará), through Fine and Standard great impact in the new materials field and has been RADARSAT images, treated using OrthoEngine SE used in some state-of-the-art companies. The main (PCI Geomatics) software in a radar measurement factor restricting this process in more generalized in- approach (stereoscopic radar). In addition, the po- dustrial applications, however, is the nature of its tential for generating topographical maps on the line-of-sight implanting, which makes it different or semi-detailed scale (1:100.000) will be investigated. impossible to engage in three-dimensional treat- In its second stage, improvement of the results focu- ment of geometrically complex parts at low cost. In sing on the generation of Digital Elevation Models turn, ionic implementation through immersion in in the preparation of topographical maps and Inte- plasma (IIIP) has been opening up new frontiers grated Radar Products for geo-environmental appli- and opportunities for industrial application. This cation is planned. Besides this, alternatives will be processing takes advantage of implanting without sought in the international market for devices line-of-sight and enables it to be independent of the (hardware and software) enabling GCPs to be plot- area to be treated. In the first stage, development of ted in a three-dimensional view (less propagation of part of the HIP(INPE/Metrolab) equipment in res- errors in the final accuracy of the DEMs). pect of the high-performance plasma source, was sought by using a highly efficient vacuum system and source of glow discharge with controlled poten- Development of New Kits tial. In the second, a new vacuum chamber will be 96 Destined for the Diagnosis of built and integrated into the system with a high-vol- Intestinal Parasites in Feces Samples tage pulsar with a high repetition rate and other ap- propriate equipment. Coordinator: Sumie Hoshino Shimizu Company: Generation of Digital Immunoassay Produtos Hospitalares Ltda. 95 Elevation Models using Radar Measurement with Images Approved value: from the Radarsat-1 Satellite Phase 1: R$ 35,904 / US$ 7,866

Coordinator: The project envisions the development of kits for Waldir Renato Paradella the diagnosis of intestinal parasites in feces samples. The kits may be industrialized and sold by the com- Company: pany Immunoassay Produtos Hospitalares Ltda. Re- Geoambiente Sensoriamento Remoto S/C Ltda. cent data released by the World Health Organization Approved value: shows that close to 3.5 billion people in the world Phase 1: R$ 6,500 / US$ 23,750 find themselves with intestinal parasites, of which Phase 2: R$ 122,618 / US$ 6,376.18

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450 million are ill, the majority being children living veloped and a video of the system in action. Phase 2 in tropical areas, including Brazil. Market research will be executed in two stages. The first will comple- indicates that there are few national diagnostic kits ment the existing prototypes, demonstrating the destined towards the examination of feces. This pro- complete working of the system. As a result, we will ject is divided into three sub-projects. The first deals have a set of devices and accessories that will allow with the development of a simple, practical and low- for the control and automation of some home-mo- cost kit, which will permit the collection of feces, dels, giving them “intelligence” and dynamic distan- concentrating on the parasitic elements and their ce control (telecontrol). This grouping will then per- morphological identification through the optical mit, in parallel with the continuation of this phase, a microscope, which could, at the next stage, be linked demonstration of the system to possible partners to an automatic system. The two other kits characte- and clients in various segments of the industry and rize themselves as being diagnostically advanced, for the market, maturing and strengthening their strate- use with monoclonic antibodies and the technique gic, commercial and marketing aspects, as well as the of genomic amplification. In this manner, the se- aspects of working and technological validation. The cond kit will be destined to the detection of antigens second stage of this phase will develop the same pro- of Entamoeba histolytica, by way of immuno enzyme totypes, now in a pre-industrial phase. Or in other testing (Elisa). The third kit will be for the detection words, how they should be marketed. In this stage, a of Cryptosporidium parvum, Cyclospora cayetanensis standard circuit will also be developed that can be and Microsporida, opportunist and emergent proto- integrated into any electric/electronic device, ma- zoa that are present under immune deficiency con- king it universally distance controllable by any pro- ditions, such as those observed with AIDS. This kit is grammable device, using different processors, ope- based on the amplification of DNA, using a system rational systems, programming language and of biotinylation primers, and the identification of interfaces. Then at the end of this second stage, it is the amplified products on plastic trays treated with expected to have three mobile home-models availa- avidin, internal marking probes with digoxygenin, ble for demonstration, as well as one fixed model for and enzyme conjugates anti-digoxygenin (PCR-co- testing and development. At the end of the project lorimetry). Kits for the detection of C. parvum could we will have, in a pre-industrial form: a universal also be applied for the analysis of water quality. The pre- chip Suit; a set of basic suit accessories; a group of sent project could open up paths towards the stan- outstanding residential devices, for demonstration dardization, evaluation and the production of other purposes; and control software. immune reagents applied in the diagnosis of the other intestinal protozoa, among them the giardiasis extra-intestinal infections by free living amebas. 6th BIDDING INSTRUCTIONS

Universal System of 97 Interface System for 98 Detection and Distance Control Localized Application of Herbicides on Sugarcane Coordinator: Eduardo Vettori Coordinator: Luiz Geraldo Mialhe Company: InfoDinâmica Assessoria, Company: Planejamento & Treinamento Ltda. Agrionics - Instrum. Equipamentos Agrícolas e Industriais Ltda. Approved value: Phase 2: R$ 166,200 Approved value: Phase 1: R$ 47,090 This project, in its current stage, already has pro- totypes that are demonstrating the partial working The pre-loaded instrumentation available on the of the system regarding concepts, computerized pre- market today is almost totally imported and of the sentation of marketing, functional and technological “black box” type. These characteristics, in the case of aspects, business plan – focusing specifically on one complete systems, are interesting both to the suppli- of the possible markets –, some software already de- ers and to the users, and, when correctly installed,

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guarantee a safe return on the investment. Nonethe- strain will be obtained from the Federal Rural Uni- less, the number of complete systems available on the versity of Pernambuco and another from the Pisci- national market is small, and, given the complexity of cultura Tupi company from Guairá in the State of Pa- their infrastructure, demands a high initial inves- raná. The first part of the project will describe the tment and renders obsolete the part of the non-ins- genetic-biochemical characteristics of a group of trumented fleet in use by the owner. Realization of specimens from each population. During the first this reality and the perception of a case in point in phase, the specific objectives of the project include the fleet of a group of ten herbicide dusters from the the identification of a better molecular marker for Rafard Sugarcane Distillery (União S.Paulo S/A), the study of stocks of Oreochromis niloticus and the motivated research aiming to study and develop a application of this marker for the classification of system capable of satisfying the necessities of this different stocks. In the second stage, a selection pro- agricultural operation under critical conditions (de- gram will be carried out of O. niloticus with a view to clining topography, infestation intensity, use of diffe- obtaining an improved production performance, rent products, movement risks, etc.). Currently, in which will be measured by the evaluation of the rate Brazil the use of electronic controls in dusters is res- of growth, size of fillet and volume of steak produ- tricted to the conventional systems (command of the ced. Once defined which breed produces specimens flow valves from pressure sensor signals) that attempt with the best performance, the parental populations to maintain the applied dose independent of variati- will be multiplied so as to obtain an industrial pro- ons of the velocity of the field tractor’s movement. duction of this high performance “hybrid”. There are exceptions in a few cases of imported equipment of the self-propelled type and the cost of which is extremely high, generally for application un- Implantation of der flat topography conditions. This project proposes 100 the PCR Technique for the to develop electro-electronic and mechanical com- Detection of Genetically ponents, software and operational methodology that Modified Foodstuffs will permit the assembly of a system of detection and localized application of herbicides on sugarcane. Coordinator: Janete Walter Moura

Genetic-Biochemical Company: 99 Properties of Four Strains of Tecam - Tecnologia Ambiental Ltda. Nile Tilapia (Oreochromis Approved value: niloticus), Aimed at their Phase 1: R$ 26,000 / US$ 4,000 Genetic Improvement Phase 2: R$ 47,100 / US$ 101,000

Coordinator: The objective is to implement and standardize Newton Castagnolli the PCR technique for the detection of GM foods- Company: tuffs, reproducing tests previously carried out in Castagnolli Aqüicultura Ltda. other laboratories and aiming to adapt them to the company. The project means to train personnel from Approved value: Tecam - Tecnologia Ambiental Ltda. to develop and Phase 1: R$ 34,990 / US$ 5,222.75 to offer molecular tests related to the detection of Ge- netically Modified Organisms. During the first phase, The aim of this project is the genetic improve- we carried out the detection of the genetic elements ment of Nile tilapia (Oreochromis niloticus) through introduced into foodstuffs in natura through the the dialectic crossbreeding between specimens des- PCR method, developing specific reagents, standar- cended from four populations of this species, origi- dizing the methodologies of extraction and measu- nating from different regions. On the Jurema Farm, ring the sensibility and the specificity of the reactions in Macatuba, SP,where the project will be developed, of PCR. The project was very successful in its first there are already available tilapia strains of Thai ori- phase and for the second phase we intend to develop gin imported by the Alevinopar company from Tole- our own technique, the successful marketing of do in the state of Paraná, and another strain from the which will depend on constant research practice in Municipal Foundation of 25th of July, from Joinville, the area of Molecular Biology. In parallel, we will be in the state of Santa Catarina. Furthermore, another carrying out research and standardization of PCR in

Translating Research into Business • 115 processed foodstuffs and other GMOs that may be Oral Implant Device important in the national scenario. In some countri- 102 for Front Positions with Threaded es such as the United States, Canada and the Argenti- Fixing in the Second Cortical, ne, foodstuffs that originate from genetically modifi- Articulated, with Titanium ed organisms (GMOs) have been widely accepted. Plasma Spray in the Active Region The rejection of transgenic foods on the part of some and Hydroxiapatite in the Paste, European Community and Asian countries is gene- Head with an Esthetically rating a demand for conventional foodstuffs. These Adequate Diameter and with markets are demanding the assurance of the absence an Anti-Rotational and Screwed of contamination by GMOs through their food chain Prosthesis Fixation System production. A large part of the raw materials expor- ted from Brazil are destined for these markets. Coordinator: Antonio Vicente de Souza Pinto Company: Development of Seedlings Pro-Line Serviços Produtos Quality Control in Laboratories 101 Odontológicos Ortopédicos Ltda. Allied to Biotechnology Approved value: Coordinator: Phase 1: R$ 49,700 Monique Inês Segeren The project aims to develop a dental implant de- Company: vice, the technical appeal of which is in the combina- ProClone - Mudas Matrizes de Laboratório tion and use of strong points from the two models Approved value: currently most commonly used: the bi-cortical im- Phase 1: R$ 50,000 plant and bone integration. From the first model we Phase 2: R$ 213,000 will use the concept of the fixation of the device in the second cortical, drastically reducing the time for The objective of the project is the large scale pro- the placement of the dental prosthesis. From the se- duction of healthy seedlings of plants from the Bra- cond model we will apply the design of its crown, zilian flora through tissue culture or micro propaga- which offers a much greater capacity than the first in tion in vitro. In ornamental plant market segment, terms of esthetics, asepsis, and the monitoring of the orchids are plants with great commercial value and prosthesis system in the replacement of front teeth with enormous export potential. Orchid seedlings and treatment of the active surface for a greater area can easily be obtained through micro propagation in of bone integration. Both are models that adopt tita- vitro. Currently they are produced in small quantiti- nium as the basic material for their construction, es by collectors, small producers and household gro- which will be retained in this project. The methodo- wers. The proposal is to create an infrastructure for logy to be used in the project follows sequentially the producing seedlings and a means of cultivation to following activities: modeling and dimensioning of feed a network of laboratories and producers. The the prototypes; mechanical testing of wear and tear, intention is to install distinct processes for the pro- compression and cutting ability between the con- duction of micro propagating cuttings and to meet ventional bi-cortical model and the model being the needs of a network of cuttings producers, suppl- proposed here; production of prototypes; and their ying them with the means of growing, cuttings, tech- implantation in animals. niques for the implantation of these processes and quality control in situ, through nurseries and gree- nhouses specifically designed for each plant species. Development of The developed work within an integrated network of 103 a System of Ionizing allied laboratories will improve supply to the inter- Radiation Monitors nal market and open the way for exporting. During this project a supervision system of the process of Coordinator: cloning of each culture will be developed, as well as Thomaz Ghilardi Netto the definition of commercial standards for each la- Company: boratory in the network. Improvement programs of MRA Indústria de Equipamentos Orchids and Zantedeschia (Calla) through hybridi- Eletrônicos Ltda. zation and mutations will be carried out.

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Approved value: grid) both uniform and non-uniform. The methods Phase 1: R$ 35,607 of primitive variables and finite volumes will be used. The solutions will be seek to simulate and to forecast The company is developing research into biome- incompressible outflow and variable density outflow, dical instrumentation, mainly in projects linked to the permanent and non-permanent outflow, turbulence control of the quality of radiology images. The project and non-turbulence, regular and non-regular do- intends, during the first phase, to compact an analy- mains, the consideration of bed variations and coas- zing system of an X-ray beam through alteration to its tline variations and elevation of surface water. acquisition hardware, looking to simplify its applica- tion in quality control programs in healthcare. In the compacting of the system, some micro controlling de- Development of a Micro vices, available on the market, will be evaluated, in or- 105 Controlled Deformation Gauge der to provide a connection of the acquisition modu- with a Communication Interface le to a notebook. Furthermore, we intend to collect data with the intention of studying the behavior of Coordinator: the system with X-ray beams generated by electrical Alexandre César Rodrigues da Silva feed of half waves and full waves and to research ma- Company: terials, to build a prototype of an ionization chamber Engel - Indústria e Comércio and to study its behavior towards the energy of pho- de Instrumentos Ltda. tons used in radio diagnostics. During the second phase, the intention is to produce compact prototypes Approved value: of equipment, kVp gauges, dosage rate, dosage level, Phase 1: R$ 20,390 exposure time, semi-reducing cover, built-in filtering, in keeping with market demands. The project aims to develop a deformation gauge for application both in test laboratories and the rese- arch of new materials and in the civil engineering General Use Computer structures. The desired equipment will have a very 104 Program and Software for the precise measurement system (better than 0.1 per Modeling of Drainage and for the cent) and high resolution (1 micrometer/meter), the Transport of Contaminants functions of which will be monitored and controlled in Natural and Artificial Waterways by a microcomputer control system. Furthermore, a communication interface will be made available com- Coordinator: patible with standard IBM/PC microcomputers, so as Swami Marcondes Villela to facilitate the analysis of the data through specific software programs. Since it possesses predominantly Company: digital properties, the intention is to implement seve- SHS Consultoria e Projetos de Engenharia Ltda. ral of its circuits by means of matrixes of logic circu- Approved value: its (FPGA), which are more efficient, consume less Phase 1: R$ 41,558 power and occupy less space. The conclusion of this project will deliver into the national market a quality The project aims to develop general use compu- product of flexible use, and high technological value, ter programs and the respective software for draina- since at the moment no other such manufacturer ge modeling and for the transporting of contami- exists in this market. The equipment has guaranteed nants in natural and artificial waterways. The applications in the areas of materials testing and the products from this project should solve, in a general monitoring of civil engineering works. way, continuity equations, Navier-Stokes equations, Reynolds equations, transportation equations with turbulence parameters and transport equations of Electro-Mechanical other scales. The solutions will be applied to systems 106 Packaging of Micro of Cartesian coordinates both 2- and 3-dimensional, Pressure Sensors 2-dimensional Polar coordinates and 3-dimensional Cylindrical coordinates. These solutions will be gene- Coordinator: rated through alternated grids (movement quantity Alfeu Fissore

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Company: The treatment for pulmonary tuberculosis con- Fissore - Consultoria e Assessoria sists of the association of medication, good nutrition Técnico-Científica S/C Ltda. and rest. The first drugs used were streptomycin, iso- niazid and para-aminosalicylic acid, all capable of Approved value: eradicating the tuberculosis bacillus from the hu- Phase 1: R$ 18,400 man organism. Other effective drugs are etambutol, rifampicin, thiacetazone and pirazinamid. Although Pressure transducers based on silicon micro sen- the infection is halted quickly, the complete cure re- sors are already a technological reality and constitu- quires several months of treatment. Thus, it is of te a true revolution for different industrial segments strategic importance that Brazil becomes self-suffi- such as automotive, medical, biomedical, control, cient in these medicines. The production of pirazi- etc. The principal component of the transducers is namid was discontinued in the country and, in the the silicon micro pressure sensor, the design and ma- last 8 years around 79 tons of technical pirazinamid nufacture of which depends on its application. It is were imported, which signified a foreign exchange impossible to develop various different types of mi- cost of US$ 3,333,678. The objectives of this project cro pressure sensors in the medium term here in are: 1) the development of clean methodologies for Brazil. The research activities of this project have the production of drugs for the treatment of tuber- been under development for close to five years and culosis (pirazinamid); 2) subsequent implementa- have reached a point in which the results obtained tion on an industrial scale. The methodologies to be encourage their industrial exploration. The proposal developed consist of: 3) studying the oxidization of is to design and develop miniaturized electromecha- quinoxalin 6 through the use of ozone with catalytic nical packaging for the enclosure of silicon micro quantities of manganese dioxide, and 4) studying pressure sensors purchased abroad, in this way as- the synthesis of pirazinamid from 2,3-diamino-pro- sembling the pressure transducers. The micro sensor pionic acid 9. will be assembled on a ceramic plate made using thick film technology. In principle, two types of ex- ploratory prototypes will be developed, denomina- System for the Management ted Type A and Type B. Type A will make use of a of “Dusting” in Agriculture with pressure micro sensor made with ultra modern tech- 108 the Technology of Automatic nology and, in this case, the user will have to supply Acquisition of Field Data the circuitry for the regulation of signal standard for its specific use. Type B is a throw-away transducers, Coordinator: the chip for which is also made with cutting edge Cléber Rinaldo Manzoni technology, of high performance, especially design- ed to satisfy all existing requirements for medical Company: instruments. The pressure sensor must be compen- Enalta Inovações Tecnológicas para Agricultura sated and calibrated using laser trimming of thick Approved value: film resistors. The transducer integrates a high per- Phase 1 + Scholarships: R$ 66,342.60 / US$ 2,000 formance chip tolerant to radiation, with thermal and calibration compensation circuitry, and a pro- The research intends to develop a system for the tective gel in a low cost capsule. management of dusting /spraying activity in agricul- ture with technology of automatic acquisition of fi- eld data, which aims to enable the farmer to have to- Use of Clean Technology tal mastery over the information involved in this in the National Production 107 activity, such as: data directly concerning the equip- of Active Principles with ment i.e. rate of application (I/ha), velocity of tractor Pharmacological Activity (km/h), quantity of raw material to be applied per treated area and other data involved in the control of Coordinator: the application of raw material (type of application, Moacir de Mancilha type of raw material to be used, stage of growth of the Company: product, planting phase, hours/machine worked, re- Synthon Especialidades Química Ltda. asons for stoppages, location of application and oth- ers.) All of the above related data will be collected in Approved value: the field by collector modules of mobile and fixed Phase 2: R$ 23,882.00

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data (hardware) and afterwards uploaded onto a per- Approved value: sonal computer, to be subsequently transformed into Phase 1: R$ 49,150 information (management software) that will enable the farmer to automate the programming of the ma- The project is a study into the feasibility (phase 1) chine’s activity, to evaluate the performance of the and the implementation (phase 2) of devices for the operator, of the agricultural equipment (tractor and extraction of features and the verification of a digital sprayer/duster) and of the process as a whole. fingerprint, through the use of an image capturing sensor based on network capacitance CMOS (semi- conductor) and a high performance digital signal pro- Portable Inductive cessor, resulting in the first commercial device of its 109 System for the type to be developed in Latin America. The main cha- Imaging of Steel Bars in racteristics of this proposed device are: implementati- Concrete Structures on using innovative algorithms developed here in Bra- zil, thus improving the processes involved (image Coordinator: capturing, treatment, extraction of characteristics, sto- Isaac Newton Lima da Silva rage and comparison); interface inclusion for smart cards, introducing a new security element in the trans- Company: port and storage of digital fingerprint characteristics Tecnolab do Brasil Instrumentos and off-line verification; use of devices based entirely de Lab. Computadores Pessoais Ltda. on semiconductors, with no optical part for image Approved value: capturing, rendering circuits more robust and much Phase 1: R$ 13,295 / US$ 747.30 more compact; low number of components (proces- sor, memory and sensor), small motherboard area, The project has as its goal the development of the commercially available and locally made components; prototype of a compact version of a system for the standardized communication interfaces, facilitating inductive scanning of steel bars in concrete structu- the integration with existing systems or products res, producing 3D images starting from a beta versi- (OEM) or for the development of new products. on already developed, which produces 2D images. At the end of phase 2 of the project, it is intended to have the first version of a device of wide application System of Tracking, Control in the civil construction industry, as well as in other 111 and Remote Immobilization sectors. Today there is greater concern about the sa- fety of concrete structures than before. One of the Coordinator: most important aspects in such structures is the Samir Aued condition of the steel reinforcements. Considerable Company: resources are being spent on research to develop Standard Telecom Ltda. tests on the destructibility of such components. The magnetic scanner is the most advanced instrument Approved value: for the inspection of concrete structures, providing a Phase 1: R$ 16,580 / US$ 7,800 magnetic image of the metallic structures. This pro- ject intends to make available to the Brazilian mar- The main objective of the project is to develop a ket a complete system, including a magnetic scanner control system for the monitoring, tracking, and re- and controller, data acquisition, software for vie- mote immobilization of automobiles. This objective wing, processing and analysis of the image of the will be achieved through the selection and incorpo- concrete, as well as instruction manuals. ration of the latest generation alternative technolo- gies (such as the two-way pager), which will allow the maximization of the cost/benefit relationship of the Recognition of final product, making possible its popularization and 110 Digital Fingerprint use on a large scale. The system permits the location, tracking and remote control of vehicles, through the Coordinator: use of satellite locating systems (GPS – Global Positi- Rogério Souza da Mata oning Systems) and of the data transmission techno- logy of two-way pagers (Reflex protocol). The fact Company: that a large part of the national territory is already S.M.A Tecnologia Comércio e Serviços Ltda

Translating Research into Business • 119 covered by paging systems, increases the reliability of Reticulation of Coating, the proposed security system (there are plans to ex- 113 Based on EPDM using tend the two-way pager coverage). The proposed sys- Ultraviolet Radiation (UV) tem will permit the incorporation of an immobili- zing unit via magnetic transponders already Coordinator: developed and in the initial phase of commercializa- Ricardo Aurélio da Costa tion by Standard Telecom, which will allow for both Company: the local and remote monitoring and immobilization Área Química Ltda of vehicles. The system will permit the development of new commercial applications in the areas of mo- Approved value: nitoring and control of freight transportation, secu- Phase 1: R$ 32,207 rity systems and anti-theft of vehicles; the monito- ring and remote control of mobile devices, enabling The chemical industry patented a series of multi- the implementation of various applications in the composite polyolefin- amorphous- waxes, such as non area of tele-metrics and tele-command. conventional keratins for impermeability and pain- ting. The multi-composites based on EPDM are sta- ble solutions, used to modify the interfacial properti- Study for the es of different substrates. Nonetheless, the coating of 112 Development of Distance non-reticulated EPDM, obtained after the evaporati- and Level Gauges Using Microwaves on of the solvent, is recommended for temperatures (radar) and Laser (optical) close to or below room temperature, restricting the use of this coating to these conditions. The project Coordinator: proposes to study the technical viability of producing Willian Paul Yuzo Abe coatings based on reticulated EPDM, in the ultravio- let region, with speeds of reticulation compatible with Company: its continuous manufacturing process. The experi- Level Control Comércio, mental work forecasts the preparation of the coatings Indústria e Representações Ltda. with EPDM starting from solutions prepared accor- Approved value: ding to the description of Patent PI 8701355-0. The Phase 1: R$ 26,240 / US$ 9,417.54 solutions will have additives of photo initiators and commercial reticulation agents. The choices of the The objective of the research is the development photo initiators and reticulation agents will be made of a level gauge for tanks which will have the proper- in accordance with the solubility of these two additi- ties of good precision and high reliability under the ves in the solvents or mixtures, used for the prepara- most diverse applications. The current techniques tion of the elastic-like solutions. The EPDM coatings used for this type of measuring gauge with the avai- will be prepared and reticulated, varying the concen- lable devices on the market are: capacitance measu- trations of the photo initiator and the reticulating rement, magnetic float, manometer or differential agent, irradiation time and thickness of the coating. pressure transmitter, pendulum, ultrasound, radar and laser. The types of gauges proposed as objects of this research, that is to say, radar and laser, eliminate Gearing Pump one of the large problems of level or distance sen- of Variable Flow sors, which is direct physical contact with the pro- 114 duct to be measured. This is also the advantage of ul- Coordinator: trasound. However, contrary to ultrasound, which José Luis Bertazzoli depends on the medium of propagation, the propo- sed types don’t suffer interference from temperature, Company: pressure, density or dielectric constant. The potenti- Hidrometal Indústria e Comércio al users are all those who need precise measurements de Equipamentos Hidráulicos Ltda. of distance or level. The existing manufacturers of Approved value: the proposed equipment are all foreign and number Phase 1: R$ 46,520 merely five companies world-wide. Since there are so few dealing with this high technology, in prices The objective of the project is to develop a gea- charged in Brazil are extremely high. ring pump of variable flow. The expression V = M.

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pd. W determines the volume of fluid displaced per crown, containing the latest generation of super turn, with m = module, pd = primitive diameter and abrasives, sintered in ceramic molds, with the em- W = useful width of the gearing. The dimension ployment of non-conventional processes in its ma- “W” is also defined as the position in which the ge- nufacture which reduce its final cost. The parame- ars are connected among themselves, that can vary ters for the operating of the tool will define the final from zero up to a maximum limit. The empty spaces properties both of the drill press and the drilling co- between the teeth on the linking sides of the gears lumn. The technical-economic viability of the deep are filled by the teeth of internal gears, with such drilling tool is the crucial point for the viability of precision that they prevent leaks. The gearing of the the complete proposed system, permitting a reducti- internal teeth, that seals the motor gearing, have axi- on in the order of 70 per cent in the value of the in- al movement. The gearing of the internal teeth, that vestment in equipment, occasioning a proportional cover the mobile gearing, do not possess this move- reduction in the final cost per meter drilled. ment. The gear movement of the mobile gearing is free in the axial paths and also acts as a command piston of outflow and pressure, doing away with Optical Components what in the competing products is an expensive ac- 116 in Injected Plastic with cessory. The piston advance results from the internal Non-Spherical Surfaces forces transmitted by the pressure of the command oil and by the pressure in the gearing chamber. The Coordinator: recoil of the piston is carried out through the allevi- Sérgio Antonio de Almeida Nobre ation of the command oil, which increases the resul- Company: tant internal force on gears’ side. If these opposite Optovac Mecânica e Optoeletrônica Ltda forces balance each other out with springs, economic and reliable load sensing control is obtained. Approved value: Phase 1: R$ 33,000 / US$ 16,236 Phase 2: US$ 140,000 System for the Low Cost 115 and Fast Drilling of Deep Tubular The goal of this research project is to develop Wells in Hard Rock, for the technology for the manufacturing of high qua- Obtaining Underground Water lity optical components with non-spherical surfa- ces thus qualifying the company in the manufactu- Coordinator: re of non-spherical optical components, products Roberto Megumi Tomaoka that use this type of component and also to project Company: and build molds and necessary inserts. The manu- Megatech Produtos Mecânicos Ltda. facture of injected plastic optical components with non-spherical surfaces involves component project Approved value: aspects of the molds, inserts and necessary tools, Phase 1: R$ 16,970 which even in worldwide terms, are only accessible to a few companies. Products with applications of The project aims to develop a system of fast and plastic optical components are in increasing de- economic drilling of tubular wells for obtaining un- mand, given the volume of sophisticated products derground water in geological formations composed and the low cost that they bring to the market each of very hard rocks, with a final drill diameter of 153 year. Examples of products that use this type of mm, and a depth of 350 meters. The system will have technology are the low-cost video camera, compact as innovation, three basic characteristics: a light and disc readers, optical linkages, infrared and visible compact drill press for its size, allowing a version light sensors, etc. The surface of the inserts that with a mast of low altitude (2.5m) brought into play make up the most critical parts of the cavity of the by a motor with power of around 100 HP with required injection molds possess optically polished hydraulic advance and semi-automatic transmission surfaces that are devised by elaborate mathematical (power shift), permitting centralized commands and functions. For the manufacturing of these surfaces operation by only two technicians; drilling column it is necessary to have equipment with numerical equipped with a system to remove cut rock through control, with advanced control prerequisites and its interior, up to the surface, using a small barrel extremely critical mechanical stability, since the se- wire-line; use of a deep drilling tool in the form of a ams of the machinery tooling must be less than the

Translating Research into Business • 121 width of the light wave over which the component A Computerized System for the will work, that is to say, the surfaces must present a 118 Analysis of Human Chromosomes final finish comparable to that obtained through optical polishing. Coordinator: Antônio Francisco Junior Company: Production of Pigments Atonus Engenharia de Sistemas Ltda. 117 by Monascus sp in Semi-Solid Fermentation Approved value: Phase 1: R$ 21,600 Coordinator: Phase 2: R$ 173,520 / US$ 22,545 Beatriz Vahan Kilikian Currently there are various techniques for the Company: study of human chromosomes, both in a morpholo- Germinal Indústria e Comércio gical focus, whose main technique is G banding, and de Produtos Químicos Ltda. through methods of molecular cytogenetics, known Approved value: as FISH (Fluorescent in situ hybridization). In spite Phase 1: R$ 21,000 / US$ 10,229.32 of the growing demand, the offer of automatic sys- Phase 2: R$ 197,260 / US$ 20,685.56 tems that assist the work of the geneticist in the col- lection of data, in the generation of karyotypes and The present project proposes to set up a produc- in the study of FISH, is small. The goal of the present tion process for organic pigments of microbic ori- study is to develop a computerized system using vi- gin, to be used in food. Species of Monascus fungi sion techniques by computer, capable of assisting the will be cultivated in a semi-solid substrate made geneticist both in the execution of the analysis of the from the cassava root, this being one of the innova- form of the human chromosome, in order to carry tive aspects of the project, since the fungi referred to out the assisted pairing of the chromosomes, and are traditionally cultivated through a rice base in also to help in the collection and analysis of data for China and Japan. The use of a low cost substrate, carrying out the FISH study. Through FISH it is pos- abundant in Brazil and non seasonal, constitutes an sible to execute the cytogenetic diagnosis of embryos advantageous aspect over the traditional process. and fetuses with increased risk from chromosomal The implantation of a process under controlled problems. In the case when the FISH is carried out at conditions of fungus cultivation constitutes another the initial stage of cell division, one can both deter- aspect to be highlighted, since in the original coun- mine some illnesses as well as the sex of the future tries the fermentation is carried out without con- generated individual. This study makes use of lumi- trols, under appalling hygienic conditions. The ob- nescent chromosome probes that intrude into part taining of a product under controlled conditions of the DNA chain of a chromosome, emitting light would qualify it for entry to the market for food in- of determined wave lengths. Optical filters are then gredients. It is estimated that the Brazilian con- used to select the light wavelength that needs to be sumption of the red pigments of Monascus, monas- analyzed. The capture and analysis of this luminous corubramine and rubropunctamine, is in the order standard is the essence of the FISH study. of 500 tons of product per year, which represents a turnover of close to R$ 5 million. This consumpti- on may increase when one considers that cochineal Geophone – Integrated carmine and nitrate salts and nitrite are still being 119 System for Obtaining used, which give rise to toxicity due to the formati- Geo-Referenced Information on of nitrosamine. The present project, ultimately, for Emergency Services aims to produce organic pigments, but social as- pects – job creation – and technologies – implanta- Coordinator: tion of a technological base for this and other pro- Flávio Gonçalves Boskovitz cesses of similar characteristics – will be taken into Company: consideration. Geodados Mapeamento e Pesquisa Ltda.

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Approved value: The present project is the fruit of a partnership Phase 1 + Scholarship: R$ 54,138 between the process development laboratories of the Phase 2 : R$ 207,085 Chemical Engineering Department of UFSCar (Fede- ral University of São Carlos), of the Work Project and This project is looking to develop Geophone – of the Industrial Installations of the Production Engi- an integrated system of geo-referenced informati- neering Department also from UFSCar along with the on capable of instantly localizing on the digital Cereals and Chocolate Technology Center – Cereal map of the city the origin of a phone call, to carry Chocotec, linked to Ital, and the Chocolates Finos out a spatial analysis for creating data on the dis- Serrazul Ltda. During this second phase, the project tance of the point of origin of the phone call to develops simultaneously and inseparably in two di- other aspects of interest (hydrants, police pre- rections: the management of the processes and the cincts, schools, hospitals etc.), the best route from technology of the products. In the case of the mana- point to point, to look for tabulated data relative to gement process, the intention is to direct efforts to- the point of origin, and finally to generate, store wards the preparation of the company’s management and print out a report containing this information. and production team, for the feasibility of the process Geophone is a system that uses, in an integrated of technological innovation and in the preparation manner, a phone call identifier, a microcomputer and training of their people for a new manufacturing and an exit device. The focus of the research will process to be introduced in a new specially designed be to achieve an improvement in the integration of industrial plant. From the technological point of view the call identifier with the microcomputer and of the new products, the project aims to develop, in with the system search platform, in the analysis partnership with a team of researchers from the Cere- and exhibition of the information relative to the al Chocotec Ital’s, new recipes: the traditional cove- origin of the telephone caller, so that the operators rings of chocolate based on buttered cacao bean (whi- (firemen, police, rescue and ambulance) provide a te, bitter and milky) and four new types of recipe, better and quicker service. The Geophone is viable. denominated organic chocolate (with components It is already part of the reality of a Center of Atten- produced without the use of harmful agricultural tion and Dispatch of the Military Police of the Sta- chemicals), chocolate plus (enriched chocolate), cho- te of São Paulo, implanted within the 17th Battali- colate diet (without sugar) and chocolate without lac- on in the town of São José do Rio Preto. During tose. It is worth highlighting the fact that on the Bra- phase 2, the research emphasis will be to make a zilian market, and according to our knowledge, on the general improvement to the system, creating new world market, as yet there are no recipes for organic, tools for geo-processing, improving those already enriched or non-lactose chocolate. in existence, improving the routines for better per- formance, developing a fusion between the Opera- tional System of the Military Police and Geophone Money Exchange and remodeling the data bank with links to exter- 121 System and Foreign Trade nal data bases. The expansion of the Geophone service to three other towns will be fundamental Coordinator: for its improvement and the design of efficient Valter Francisco Arruda Alves methodologies of geo-referencing, geo-codificati- Company: on and the acquisition of field data. Invenire Internacional Informática S/C Ltda. Approved value: Phase 1: R$ 45,230 Flexible Manufacturing Phase 2: R$ 187,140 / US$ 30,000 120 of Chocolates and Innovation in the Basic Line of Products The objective of this work is to develop an inno- vative computerized system for operational support Coordinator: in international exchange and trade in financial insti- Paulo Ignácio Fonseca de Almeida tutions. The system will support the banking transac- tions related to the control of day to day operations, Company: providing a managerial vision of all of aspects of the Chocolates Finos Serrazul Ltda. business. The system will be innovative in the manner Approved value: that: it will use object-oriented technology; it will Phase 2: R$ 119,800 / US$ 12,355 support the concept of frameworks; it will blend the

Translating Research into Business • 123 object-oriented development with the development tion of some of the above difficulties. The new pro- of systems especially based on regulations; it will be grams in non-linear electronic editing have come to multi-level; it will make use of Internet-derived tech- create a new possibility for controlling the length of nologies such as communication backbone; and it duration of the filming compatible between the cine- will be fully integrated into the external networks matographic and videographic registers of large such as Sisbacen and Swift. This system will show sig- stretches of urban landscape or of highways for the nificant advantages over current systems, be they tho- purposes of city planning and landscaping. The pre- se available on the market, or internally developed by sent project proposes a revision and fine-tuning of the banks themselves. The proposed system will com- the experiment already carried out and the technical prise the following modules: Basic Registration Mo- working up of an application. dules (client, currency, countries, indexes and others); Commercial Operations Module (exportation, im- portation, inter-banking and financial); Operations SETAS – Electronic Table Module; Accounting Module; Management 123 Safety Triangle System Control Module; Reciprocity of Clients; Reciprocity of Bankers; Cash Flow in Foreign Currency; Cash Coordinator: Flow in National Currency; Country Risk; Market Francisco Rafael Meyer Pires Risk (Exchange and Credit); Raising of Foreign Cur- Company: rency; and Operations Yield. Initially, a prototype cor- AUTTRAN - Automação de responding to a Control Module of Exchange Con- Transportes - Indústria e Comércio Ltda. tracts will be developed. Approved value Phase 1: R$ 75,000.00 7th BIDDING INSTRUCTIONS Phase 2: R$ 261,900.00

The Electronic System of Safety Triangles (SE- CD-ROM for TAS), aims to introduce an innovatory concept for 122 City Planning the prevention of road traffic accidents, based on di- rect warnings to motorists, within their vehicles. Coordinator: One of the great advantages of the system, from the Eleonora Seligmann road safety perspective, is the possibility of alerting Company: drivers immediately a problem occurs, long before Cutin & Cafruni Consultores Associados S/C Ltda the obstacle on the highway is visible to the driver. Many scenarios, with the frequent occurrence of se- Approved value: rious accidents could be avoided or be reduced in se- Phase 1: R$ 40,200.00 riousness. The main point of SETAS is the Sinalerta equipment, the development of which is being pro- One of the difficulties encountered in the evalua- posed here. Sinalerta is a device installed in vehicles tion of urban landscape for the purposes of architec- and also at fixed points along the highway. In vehi- tural projects, urbanization projects, projects for the cles, the devices are transceivers for short distance control of urban landscapes and highways has been communication which, in the case of a collision, au- that of finding a methodology that deals not just with tomatically activate, in a radius of 300 meters, a war- quantitative data, but also with qualitative data. The ning signal which is received by vehicles equipped evolution of General Cinematic Scenography tech- with the Sinalerta, and other vehicles by cascade ef- nology applied to City Planning has pointed to some fect, will also reduce their speed, even though they practical results which go beyond the methodologies are not equipped with the Sinalerta. In addition, the usually employed in work of this nature. The surveys motorist with the equipped vehicle will be able to ac- and inventories of urban landscape already carried tivate the Sinalerta manually when confronted with out use restitutions of a mnemonic order expressed an accident or a situation of imminent danger. The in sketches, drawings, photographs, films, enquiries fixed units, which can also be transportable, could with open or closed questionnaires, all on variable be used by the road traffic police and highway admi- bases, therefore not allowing a space-time analysis of nistrators to warn motorists. Engineering prototy- all the recorded details. General Cinematic Sceno- pes of the equipment were designed, manufactured graphy applied to City Planning allows for the solu- and tested, and the project viability proven by means

• Translating Research into Business EDUARDO CESAR

EDUARDO CESAR EDUARDO CESAR

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of the system’s deployment, operation and perfor- The project, based on analysis of the furniture mance in the field. The final planned result is the sector, proposes an innovative relationship between production of a set manufactured items of equip- the design development of furniture and the produc- ment, that are fully functional and qualified for full tion process. This relationship is based on the possi- use, which will serve as the pilot batch for the future bility of combining a form of horizontal production, commercialization phase. that is, where different components can be produced by different businesses, with the design activity which necessarily precedes this splitting up. The design de- Development of Optical tails each component: platform frames in wood and 124 Attenuator Technology sheet metal, metal drawers anticipating the possibi- lity of the use of plastic at a later stage, metal fittings, Coordinator: which today are generally imported or produced here Walter Luiz de Andrade Carvalho at high cost, and smaller components such as clothes hanger racks. To this end, the project centers on work Company: done in workshops and in the laboratory, in order to Fotônica Tecnologia Óptica Ltda. arrive at a feasible design with a performance test al- Approved value: ready approved in prototype. The project includes re- Phase 2: R$ 11,000.00 / US$ 119,190.00 search amongst users and furniture sales personnel to give an indication of the acceptability of the pro- The project aims to develop optical attenuator duct on the market and to provide elements for the technology. These components are of special impor- marketing strategy. Also contemplated was the defi- tance in the installation of modern optical systems nition of materials, the installation of the production and various types of attenuator are necessary for the unit and the production of the strategy and the pro- good administration of the optical power of a sys- ducts necessary for marketing. tem. Initially, existing models of attenuator were stu- died for the development of a component adapted especially for the needs of amplified WDM optical Ultrapurification of systems. In this case, existing attenuators present va- 126 Natural Products through rious problems, such as resistance to high powers, Molecular Distillation losses dependent on polarization and lack of control of the return loss, polarization and the attenuation Coordinator: value. The project aims to resolve these problems César Benedito Batistella using three approaches: 1) attenuation using con- Company: trolled fracture in the fusion of the two fibers; 2) the Natural Products & Technologies Ltda. use of fibers doped with metallic ions; and 3) the in- sertion of absorbent elements in the optical path. As Approved values: a result it is hoped to obtain new high performance Phase 1: R$ 41,280.00 components capable of being commercialized in the Phase 2: R$ 208,140.00 international optical communications market. This project proposes an alternative method for the refining of special plant oils by means of a mole- Design and cular distillation technique which, in addition to 125 Industrialization permitting a higher degree of refinement of the oils, of Furniture prevents heat sensitive components, such as polyun- saturated fats, from decomposing during the refi- Coordinator: ning process due to the reduced time they remain in Yvonne Miriam Martha Mautner the oil. This technique dispenses with the use of sol- vents and offers great operational flexibility, allo- Company: wing for the possibility of carrying out the refining Góes & Soares Ind. e Com. de Móveis Ltda. of several oils in the same physical arrangement. As (ex-Oficina de Arte e Design Ltda.) a result, the project will obtain oils and their deriva- Approved value: tives, such as fatty acids, mono and diglycerides of Phase 1: R$ 67,829.00 high quality to be applied in the food, cosmetic and Phase 2: R$ 307,844.82 pharmaceutical industries using plants such as mu-

Translating Research into Business • 129 rumuru palm, echium plantagineum, myris and Company: pentaclethra macroloba, since natural products have Cyrbe Indústria e become increasingly acceptable to national and in- Recondicionamento de Rolos Ltda. ternational consumers. As a consequence, raw mate- Approved value: rials previously exported with a low value and redu- Phase 1 + Scholarship: R$ 94,542.60 ced technology can be commercialized with greater added value and better technological content. The goal of the proposal is to create post-harves- ting protection processes to perfect the means by Development of a which fruits are presently stored or transported in 127 Connectable Crusher Cart linked Brazil, aiming to preserve to the maximum its quality to a Caterpillar 930 Tractor for the consumer. The processes can be active or pas- and its Application in the Production sive, depending on the type of fruit. In the active pro- of Organic Material Compost cess, the fruit will remain, temporarily, immersed in a gaseous medium, with chemical agents that selecti- Coordinator: vely impede the growth of the main micro organisms Edmar José Kiehl that are the catalysts of their premature ripening. In the passive process, the fruit will suffer a surface tre- Company: atment which will retard dehydration and will make Terraviva Consultoria Ambiental S/C Ltda. the contact with micro organisms difficult, even if Approved value: they are already present in the storage environment. Phase 1: R$ 51,770 During the first phase, the intention is to set up dis- tinct processes for slowing down the rotting of some The present project proposes to develop an fruit during the post-harvesting stage. Brazil, despite adaptable implement for machinery of hydraulic being among the largest producers of fruit worldwi- action used in organic compost material (waste) ser- de, suffers considerably when one takes into account vices that deal with the operations of loading, selec- the volume of losses that occur between fruit collec- tion and crushing of the material for improving the tion and consumption. In the case of certain pro- yield of the process and the standardization of the ducts, losses are close to 40 per cent of production, final product (compost), making possible the reduc- when typically loss should not exceed 10 per cent. tion of costs and the improvement of the efficiency of application of the compost to the soil. Compost spreading is an important process in the recycling of Study of the Technical Viability organic material on agricultural properties and in 129 for the Installation of a Bromeliad the systems of industrial solid waste and of munici- Bio Factory in the Ribeira River Valley pal garbage, eliminating the risk of pollution through direct application of the waste to the soil, Coordinator: and reducing the environmental liabilities of land fill Lirio Luiz Dal Vesco and rubbish dumps. Methods of natural compost Company: formation using machinery of type retro-excavator Atlântica Assessoria Agro Ambiental S/C Ltda. and shovel-carrier type have shown themselves to Approved value: be technically and economically viable for small and Phase 1: R$ 33,970 medium size enterprises. However, the use of these machines without the necessary adaptations for the The proposing company has been re-directing activity, leads to some limitations in productivity its business activities, and since 1999, has been esta- and homogenization of the final product. blishing bases for the installation of a bio-fac- tory/laboratory of bromeliads. The product to be obtained, bromeliad seedlings, will be sold on the Post Fruit internal and external markets. Based on the experi- 128 Harvesting Protection ences observed in other countries, notably Cuba and Costa Rica, and considering the competence instal- Coordinator: led in the area within some Brazilian laboratories – Antonio José Gomes Bettega and, furthermore, the research developed together

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with the Physiology Laboratory of Development Development of a and Vegetal Genetics of the Federal University of the 131 Bacterial-Toxoid Vaccine (VT) State of Santa Catarina –, the intention is to esta- and the Production of Immunized blish the basis for the working of this laboratory/ Yolks for the Prevention of bio-factory. Bromeliads have been the most sought Post Weaning Diarrhea after ornamental plants over the last decade and the and Edema Illness in Pigs production processes on a large scale, within a labo- ratory, will give controlled conditions, allowing for Coordinator: the control of the technological processes associated João Takashi Ohashi with them. The main commercial applications of Company: the research relate to the establishment of a bio-fac- Livet Produtos Veterinários Ltda. tory for the production of ornamental bromeliads, as a pilot project for the setting up of a network of Approved value: laboratories specialized in the processes and pro- Phase 1 : R$ 47,150 / US$ 14,215 ducts of Brazilian biodiversity. About one year and a half ago, Livet Produtos Ve- terinários Ltda. developed an experimental vaccine Survey of the Technical Parameters for and immunized egg yolks, made from samples of Es- 130 Managing a Sustainable Income cherichia coli produced from fimbriae F18ab and from Species with Medicinal Potential, F18ac, commonly associated with post-weaning diar- Native to the Atlantic Rain Forest rhea and with the illness named edema in pigs. Through the present project, the company intends to Coordinator: takes its research forward, with the production of an- Alexandre Mariot tibodies against fimbriae antigens and VT toxin in Company: chicken yolks (phase 1) and , afterwards, the produc- Atlântica Assessoria Agroambiental S/C Ltda. tion and evaluation of a bacterial-toxoid vaccine and immunized yolks in pigs, for the control of diarrhea Approved value: and the illness edema (phase 2). Post-weaning diar- Phase 1 + scholarship: R$ 35,172.60 rhea and the illness known as edema are, from the practical point of view, the largest causes of econo- This survey has as its objective the evaluation of mic losses in pig production, and, throughout the the potential for the sustained exploration of medici- world, pig populations suffer from different degrees nal plants native to the Tropical Atlantic Rain Forest, of severity of these illnesses. The economic losses are complying with the legislation in effect, from the ex- significant mainly due to weight loss, high food con- ploratory process to commercialization, contributing version, non-uniformity of size (rejected), high me- to an improvement in the local population’s standard dical costs and animal mortality. Current control of living. In the region of the Ribeira Valley the grea- programs are carried out using zinc oxide and antibi- test stretch of unbroken forestry cover in the Tropical otics, which bring with them risks to public health. Atlantic Rain Forest (TARF) can be found. The lar- Pilot experiments in the field of experimental vacci- gest part of this area shows a typical forest activity, ne developed by the company Livet have shown pro- where the consequent use is restricted to manage- mising results, with a reduction of up to 65 per cent ment strategies for the permanent maintenance of of diarrhea in recently weaned piglets, showing that the forestry cover. Under these conditions, the alter- the vaccination and the use of immunized yolks could native of managing a sustainable income is the most be an efficient method in the control of this illness. viable option, balancing economic return and the conservation of nature. Initially, a survey of the plants used by the local communities in the curing Development of a Decision and prevention of illnesses will be carried out, aiming 132 Support System in the to steer the choice of the target species of this project. Management of Reservoirs Once the plants have been chosen, demographic sur- veys will be made in permanent forest stands, loo- Coordinator: king towards the verification of the abundance of José Galizia Tundisi these species and the availability of the biomass sui- table for exploitation, seeking fundamental strategies Company: for sustainable management. Instituto Internacional de Ecologia

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Approved value: the market show themselves to be compounds con- Phase 1: R$ 52,929 taining the metal vanadium (toxic and eliminated in the urine). However, vanadium could be substituted This project intends to produce a decision sup- by other metallic compounds such as niobium (non- port system for the management of river basins and toxic metal and found in abundance in the Brazilian reservoirs, consolidating scientific experiments and territory). This alloy could give vastly superior results management practice of these systems during the compared to commercially pure alloy, and is already last twenty years. The project will be consolidated by in use in England. An increase in the contact surface an international team involving researchers from between the implants and the bone tissue is also de- four countries: Brazil, Denmark, Spain and the sirable. This increase can be created by means of the Czech Republic, and which has experience of scien- spraying of the surface with bio-inert, bio-tolerant, tific research and management programs for reser- and even bio-active materials. The most commonly voirs and hydrographic basins. The world situation used material at the moment for surface spraying are of water resources, especially reservoirs (7,500 km3 particles of aluminum oxide, which belong to the stored in all of the continents), demands the organi- bio-inert group of materials which can, partially con- zation of adequate, optimized and economic systems taminate the surface of the implants. Many implants of management due to the economic impact produ- present a format which is incompatible with that of ced by the deterioration of water quality and the cost the dental element lost, and this can lead to surface of treatment and recovery of ecosystems. There is tensions which diminish or impede a perfect bone also a great need to integrate scientific research and regeneration. management into one combined and compact group, which produces innovation and alternatives with economic and social impact. The decision sup- Development of port system will be organized beginning with the 134 a System to Increase surrounding conditions that involve hydrographic Afocal Apochromatic Zoom basins, reservoirs, force functions, hydrological data, for Ophthalmologic climatology, physics and chemistry and potential in- Surgical Microscope teractions with users. Manuals, courses, software for training and operation of reservoirs will be produced Coordinator: for environmental and waterway resource managers. Fátima Maria Mitsue Yasuoka Company: Opto Eletrônica S/A Projects for Odontological 133 Implants Associated with Approved value: Hydroxiapatite and Titanium Phase 1: R$ 44,500 Particle Coated Surfaces The objective of this project is to develop a sys- Coordinator: tem of magnification of the afocal and apochroma- Bruno König Júnior tic zoom type to be used in an ophthalmologic sur- gery microscope, which is one of the products Company: manufactured by Opto Eletrônica. This system Brastec Empresa Brasileira de Usinagem should replace the conventional system of magnifi- Approved value: cation of the Galilean type telescope that allows for Phase 1: R$ 54,203 only five magnifications (0.40; 0.67; 1.00; 1.50 and 2.50x). Considering the increases introduced by the The present proposal intends to use exclusively lens and eyepiece, the surgical microscope has total bio-active materials or materials which promote a magnifications of 05, 08, 12, 20 and 30x. With the better interaction with bone tissue such as, for exam- system of increased afocal apanchromatic zoom, the ple, hydroxiapatite and titanium in particles, to be surgical microscope will have available magnificati- sprayed over the surface of implanted dentures, crea- ons that could vary from 0.40 up to 2.50x. The opti- ting a greater surface contact, without the presence of cal system will consist of two positive doublets (len- contaminating residues. Titanium alloys have de- ses constructed of two different materials, crown or monstrated high bio compatibility with bone tissue. flint, the aim of which will be to minimize chroma- Nevertheless part of the dental implants available on tic aberration) and two negative doublets inserted

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between the positive lenses, in such a manner that Femto Indústria e Comércio de Instrumentos the two negative doublets and one positive remain Ltda. intends, through the present project, to gain fixed. Since the relative movement of the lenses is the knowledge of how to develop and produce a PC- non-linear, it will be necessary to use a sophisticated based fast sweep spectrophotometer, incorporating mechanical system of cams. The major advantage of the most recent components and technology availa- this type of system is that it lends itself to the auto- ble on the world market. A manufacturer of spectro- mation of the surgical microscope, making it much photometers, the company is aware that Brazilian easier to perform surgical procedures. consumers require a product with screens and pro- grams in Portuguese, at a price (for the product and services) compatible with national reality, in additi- Identification of Aromatic on to responsiveness and competence in attending 135 Compounds in Brazilian to their needs. New models must be continually de- Fruit for the Creation of New veloped, mainly to fulfill the demands and the stan- Aromas for the Food Industry dards of the companies with quality programs equi- valent to ISO 9000 or higher. Coordinator: Claudio de Lima Miguel Martinez Company: Development of Equipment for VittaFlavor Indústria e Comércio Ltda. 137 the Determination of Ocular Aberrations Using Wave-Front Approved value: Measurements by way of Phase 1: R$ 75,546.60 the Harmann-Shack Technique

The present project intends to set up a research Coordinator: center into national fruit, creating a data base of the Jarbas Caiado de Castro Neto aromas of these fruit. For the extraction and identifi- cation of the compounds that compose these natural Company: aromas, it will be necessary to develop updated analy- Eyetec Equipamentos Oftálmicos Ind. e Com. Ltda. tical techniques of fine chemistry, today predomi- Approved value: nantly in the hands of chemical companies. After the Phase 1: R$ 19,500 / US$ 12,250 creation of a research center in the company, it will be important expand it and have it interact with uni- The objective of this project is to develop a com- versities, for the formation of masters and doctors in puterized instrument for the precise measurement this area. Currently, research in the area of the identi- of ocular aberrations and associated refractive de- fication of aromatic compounds is restricted to mul- fects (astigmatism, myopia and hypermetropia). tinationals, with laboratories located in their original The more traditional method for refractive exami- countries. In Brazil, there are no known laboratories nations is based on the use of various test lenses, the specialized for this purpose. Isolated research exists in degrees of which vary by intervals of 0.25 diopters. some universities for the identification of some pro- This is a subjective test which leaves the patient to ducts, but not for the creation of new aromas. choose the best lens. The examination is carried out with optotypes situated a certain distance from the patient. This technique even today shows itself to be Spectrophotometer problematic when being used under certain cir- 136 Based on a Pulsating cumstances and for certain patients. A few years Xenon Lamp and Linear ago, so-called auto refractors were developed and Image Sensor made available on the instrumental market. The ba- sic objective was to eliminate the subjective element Coordinator: associated with previous methods. These instru- Lídio Kazuo Takayama ments normally measure the ametropias, projecting Company: discrete light points onto the retina. Through analy- Femto Indústria e Comércio sis of the reflection of these points the best correcti- de Instrumentos Ltda. ve lens could be calculated. These techniques of conventional refractometry, nonetheless, offer no Approved value: diagnosis, and therefore no treatment for irregular Phase 1 : R$ 34,563 / US$ 2,543.83

Translating Research into Business • 133 features of the refractory defect. The point to point Pumping System for the refractory map generated by a front wave analyzer 139 Extraction of Petroleum Using collects real data from the refractometer, without the Linear Tubular Motor simplifying it through “regular” lenses (spherical, cylindrical or toric). Consequently, the information Coordinator: obtained is the most complete. Since the advent of José Roberto Cardoso refractive surgery by excimer laser, a new field of Company: medicine has been opened up, in which the correc- Equacional Elétrica Mecânica Ltda tion of the optical defects of the ocular system can be carried out in a parametricized manner for each Approved amount: eye. In this way, the correction of the refractory de- Phase 1: R$ 42,800 fects with excimer laser could include the correcti- on of optical aberrations present in the “normal” The objective of the present project is to develop eye. Another application for the precise diagnosis of a linear tubular motor for the operation of an oil the defects of refraction is the creation of irregular pump for application in petroleum extraction sys- corrective lenses beginning with LCD or of defor- tems. The goal is to offer an alternative to the tradi- mative reflector mirrors. Such applications could tional form of extraction, which consists of a com- permit the examination of intra-ocular structures plex system whose mechanical characteristics make by means of specific pieces of apparatus with mi- extraction impracticable in low production wells or croscopic resolution. at the wells running out of crude oil. One of the cha- racteristics of the system is that the linear tubular motor must have pulsating movement and must be Micro-Computerized System for designed in a modular form, facilitating under- 138 the Gauging of Functional Parameters ground assembly. Its choice is justified by the featu- of Radio Diagnostic Equipment re of linear movement and by the absence of mecha- nical contact between the fixed part (which Coordinator: operates) and the mobile part (which is operated), Newton Sá de Miranda Curi thus eliminating mechanical losses characteristic of the traditional operation. Basically the work involves Company: three fundamental tasks: the mechanical dimensio- Indústria e Comércio Fac Ltda ning of the pump and of the pumping system; an Approved value: electromagnetic study of the linear tubular motor, Phase 1: R$ 44,000 where the electromagnetic structure of the motor will be defined; the electrical calculation and cons- The basic objective of this project is to perfect a truction of a prototype, simulation of the operation simple to operate, but nonetheless very precise piece and thermal performance, and the development of of equipment which displays all the operational pa- an electronic . rameters of radiology apparatus, evaluating its qua- lity in the very location itself where it is installed. Such equipment must be based on a system compo- System of Video-Auditing for sed of semiconductor radiation sensors, suitably lin- 140 the Control of Vehicles in ked to a support device, a digitalized signal machine Car Parking Lots Through Images and a laptop style microcomputer, which will enable the evaluation of factors of interest, ranging from Coordinator: the operational parameters of the radio diagnostic Julio Augusto Leitão Machado apparatus (dose, kVp, exposure time, wave form, Company: tube current, magnetic field, heel effect, semi-redu- Tecnima Imagem e Automação Ltda. cing cover) to the value of its focal point. The goal of the application of this system is in the quality con- Approved value: trol radio diagnostic equipment in hospitals, specia- Phase 1: R$ 10,930 / US$ 3,935 lized clinics and even in the industrial production of this equipment for the calibration of the quality pa- The system proposes to increase the security of rameters. Special emphasis will be given for its appli- vehicles in closed parking lots, resolving weaknesses cation in the mammography systems. inherent in existing commercial systems, through

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the capture of their images on entry to and exit from cost, the various sub-systems used in private or pu- the car park and the emission of a receipt specific to blic buildings, such as: security, lighting, air conditi- the vehicle on entrance, in such a way that the au- oning, audio and video security, irrigation, telepho- thorization of its exit can be given either via manual ne and Internet. Building automation or “intelligent (through the operator) or automatic (by computer building” is a question that has been widely discus- through the application of computerized vision for sed over the last few years. The need for the ratio- the identification and automatic reading of the ning of energy spent on lighting, air conditioning, number plate) comparison of both images. Increases among other sub-systems of a building’s installati- in vehicle theft have led drivers to prefer the use of ons, has led to the adoption of automation as means controlled car parks, as they provide a feeling of se- of reducing costs. Sensis has been developing digital curity and are covered by theft insurance policy. No- systems for industrial automation and, based on the- netheless, the control systems, even those automa- se developments, has turned its attention to the mar- ted, essentially are concerned with commercial ket of building automation. The current research control and don’t offer protection against theft or will define the level of the transmission of data ne- false allegations of robbery, by failing to automati- cessary for the transmission of commands and sen- cally issue receipts containing data linking the vehi- soring, as well as the group of commands for acces- cle to its owner. The entirely digital processing of the sing all of the applicable functions available in the images captured, as well as their storage together controlled sub-systems. From this data it will be pos- with the associated data (date, time and code of re- sible to define a digital network structure of com- ceipt provided to the driver of the vehicle), allows for munication and protocol communication to be im- the easy search of the images according to determi- plemented. The network structure to be defined ned criteria. The proposed system is protected should be modular and of low cost. through a patent request with Registration Number MU7802291-6 at the INPI (National Institute of In- dustrial Property), with a view to its commercializa- Development and tion for owners or operators of controlled parking 142 Classification of PET/HDPE lots, whether paid for or free, as well as its use as a Polymer Blends, Employing detector of stolen vehicles for highway police and Post-Consumer Polymers traffic control agencies. Another application, also protected through a patent request with Registration Coordinator: Number MU7600785-5 at the INPI, consists of the Alex Sandro Babetto automatic registration of the images and data asso- Company: ciated with visitors and customers in banking esta- Inbrapol Indústria e Comércio blishments and companies. de Materiais Plásticos Ltda. Approved value: Research and Development of Phase 1: R$ 35,566 141 a Low Cost Digital Network for the Automation of Buildings In this project of technological innovation, the intention is to have a blended polymer and an indus- Coordinator: trial process that permits the use of post-consump- Luiz André Melara de Campos Bicudo tion rejects of PET and HDPE packaging, adding va- lue to the re-cycled product, which will be in the Company: form of PET/HDPE blends. The objective is to ob- Sensis São Carlos Ind. e Com. tain a blend of PET/HDPE based on the use of these Equipamentos Eletrônicos Ltda-ME. 100 per cent recycled polymers, or that is to say, pre- Approved value: viously used polymers so that this blend replaces in Phase 1: R$ 23,950 consumer products, other polymer materials that are used in virgin form. Also, there is the objective of Sensis aims in this first phase of the project to other applications for the suggested recycled PET carry out research to define the features necessary and HDPE such as injection processes, since cur- for the design of a network control system for buil- rently the recycled PET is used exclusively in extru- ding automation. This network should integrate in sion processes for the production of fibers and fila- an efficient, simple form, and at the lowest possible ments, and the HDPE is used only in extrusion for

Translating Research into Business • 135 the production of wrinkled plastic and tubes for fluence on the process. Thus, there will be a starting packaging. The choice of PET/HDPE is due to their point for the development of a multi-functional large availability in both weight and volume in gar- program, formulated with a base from a dynamic bage generated by the population. database from field and laboratory results, past and present, which allow the parts manufacturer to fol- low up the performance of his products, making Development of a Low Cost possible their improvement, aiming to obtain the 143 Recycled PET Compound for the best cost/benefit relationship. The losses from wear Manufacture of Fireproof Sockets and tear in the mineral industry are considerable, so much so that, for example, the refitting of the mills Coordinator: may represent up to 20 per cent of the cost of mil- Geraldo Pedroso Filho ling. This demonstrates the importance that must be given to the metallic consumption in milling, either Company: in the search for better designs and materials or as Cameando Industrial e Comercial Ltda. well in the increase of the availability of the equip- Approved value: ment. The forms of the worn out pieces vary as a Phase 1: R$ 56,760 function of their specific application – and even then, identical pieces, working side by side with the Cameando, a manufacturer of low voltage elec- same mineral, may require different types or forms trical/electronic products, proposes to study the of design. Diverse methods have been developed to technical and economic viability of producing fire- follow up the wear and tear of mill linings, among proof sockets for florescent lamps starting from them that of control by the physical mapping by ul- recycled PET. In order to reach this goal, it will be trasound and control by calibration. necessary to add functional raw materials to the recycled PET, in a double ringed extruder for the preparation of the compounds. The compositions of 8th BIDDING INSTRUCTIONS recycled PET will be planned out with the help of factorial projecting. The recycled PET compositions will be evaluated in a prototype product, obtained Training System for through injection. This type of prototype was cho- 145 Chemical and Petrochemical sen because of the level of geometrical detail of the Processes (STOP QP) mold, looking to truly evaluate the difficulties of in- jection molding and production. The only evaluati- Coordinator: on to be carried out on the experimental sockets will Alexandre Carlos Brandão Ramos be flammability test UL94. Company: Laboratório de Informática Aplicada Software for Approved value: 144 the Development Phase 1: R$ 18,000 of Worn Parts Nowadays control centers for processing units Coordinator: may have two types of system. Analogical Control José Bruno Neto Systems - ACS, which use technology from the 1970s which require several operators controlling the va- Company: rious subsystems. And Digital Distributed Control DuraSteel Engenharia Systems - DDCS, of more recent technology, which Comércio e Representações Ltda. are micro-processed, facilitating the control and op- Approved value: timization of processes by computer, reducing hu- Phase 1: R$ 48,107 man intervention in the normal operation of the process, intervening only when operational instabi- Through this work, it is proposed to develop a lities occur, stops and starts. The current tendency is computer program destined to follow the wear and for ACS gradually to be replaced by DDCS, in view tear of parts of a mill, with the objective of obtaining of the great versatility of these systems represented the parameters of the variables that have a direct in- by the interface with external computers. This ad-

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vantage, however, does not favor process operators te chemical and physical characterization of the pro- with little experience. STOP QP is there to meet the ducts obtained (AGC and CMS) with the collabora- training needs of these operators, providing kno- tion of third parties. The AGC developed will also be wledge of corrective actions needed to resolve opera- used as raw material for the production of CMS in tional emergencies and instabilities, displaying seve- phase 2 of the project. In the first Phase, the develop- ral facilities, among which: multimedia tutorials ment of the process for obtaining CMS using plasma which demonstrate the various subsystems to be will be carried out using small samples produced in operated, the function of each process and the ope- UNINEP. The conversion of AGC into CMS will be rational procedures; interactive multimedia courses carried out with the creation of micropores (d < 4 with specific knowledge tests at the end of each sec- nm) of homogeneous size to retain by adsorption tion and gradings for the next; simulation and visua- specific molecules and radicals, even those of low lization of the functioning of the subsystems of the molecular weight. The micropores will be produced processing unit in normal and emergency situations; by the adaptation and utilization of caged hollow-ca- and monitoring and timekeeping of the users ac- thode cold plasma technology developed in ITA’s tions under normal and emergency situations; ac- LPFI. The anticipated effect is the blocking of meso- companying the operator’s learning process with and macro pores produced by the depositing of car- graphical displays of performance. bon followed by reactivation and/or opening of nar- row channels on the surface due to selective corro- sions produced by the reactive plasmas. Phase 2 of Synthesis of the project will entail the work of setting up a com- 146 Molecular Sieves from plete system for the production of Activated Carbon Carbon Precursors Molecular Sieves on a pilot scale, in Multivácuo, and the consolidation of the applicability of this product Coordinator: in areas such as: vacuum filters in general, air filters Aparecido dos Reis Coutinho for clean rooms and hospitals, air processor and ad- sorption of residual ozone in collaboration. Company: Multivacuo Comércio de Filtros Ltda-EPP Approved value: Analysis of Fatigue in Phase 1: R$ 65,840 / US$ 5,130 147 Semi-articulated Trucks Phase 2: R$ 227,090 Coordinator: This project aims to develop and produce a Car- Carlos Alberto Nunes Dias bon Molecular Sieve (CMS) using national, renewa- Company: ble raw materials (biomass), with a view to replacing MASA Peças e Serviços Ltda. the activated aluminum molecular sieve, currently imported, for use in the special filters produced by Approved value: the company. The project also aims to set up a pilot Phase 1: R$ 35,300 manufacturing facility for the production of Activa- ted Granular Carbon (AGC), to be used in replace- Many goods vehicles, such as semi-articulated ment for conventional powder-form activated car- tanker trucks for the transportation of bulk or liquid bons and also to serve as a basic material for the cargoes, are used in Brazil for the freight of liquid design and building of new filter models for various and corrosive liquids. Despite being built to some applications. In phase 1 of the project it is intended Brazilian specifications and in compliance with to carry out work to demonstrate the technical viabi- weight regulations, owing to the state of the road lity of the process: the setting up of a pilot produc- surfaces these components have manifested fatigue- tion infrastructure for the production of AGC in the induced collapse, characterized by the occurrence of company in order to embrace and establish the car- fracture in the region of the rear suspension bearers, bonization and activation of biomass technology de- causing cracks in the tanker body and spillages of veloped in UNIMEP’s Laboratory for Carbonous corrosive products. This study will present an analy- Materials (FAPESP Project Process 95/09627-6); de- sis of the phenomenon of fatigue in semi-articulated velopment of the methodology of transformation of tanker trucks, taking into consideration the complex activated carbons into CMS in the Laboratory for dynamic loading acting on it by virtue of tire/road Plasmas and Processes (LPP) of ITA; and the comple- surface contact. A methodology will be developed

Translating Research into Business • 137 based on the application of the SN curve in conjunc- condensed water and enables the maintenance of the tion with the Palrngren-Miner rule, in order to defi- air within the standards laid down by law. The inclu- ne the accumulated damage associated with every sion compound will be prepared, in the laboratory dynamic demand, enabling a definition of the ope- phase, using the coprecipitation and liofilization rational life of the semi-articulated tanker truck. The methods. Aqueous solutions of cyclodextrine are dynamic tensions acting on this equipment will be mixed with the active ingredient in predetermined obtained experimentally, with the instrumentation estequiometric proportions, in constant agitation of a semi-articulated tanker truck, and they will be and, when necessary, using heat, thus obtaining the recorded when it goes over a specific route. With the supramolecular compound. The inclusion com- aid of the use of the method of Finite Elements for pound will be supported in the ceramic base matrix. the definition of acting static stresses on the semi-ar- The matrix may be prepared from ceramic dusts ob- ticulated tanker truck, a proposal for possible altera- tained from non-conventional chemical processes tion to the geometry of this component will be eva- such as co-precipitation and hydrothermic, with luated, with a view to reducing the stresses acting on controlled microstructure. The ceramic matrix is the region of the circumferential and longitudinal kept, after the controlled thermic treatment to ob- solders. The idea is to suggest alterations in the ma- tain the desired microstructure, in an aqueous solu- nufacturing process of the semi-articulated tanker tion for chemiabsorbtion of the active ingredient truck with the aim of reducing the defects introdu- and/or the inclusion compound, under agitation ced by the use of soldering the metal sheets and ac- and strict pH control. The control of the stages of cessories which make up this piece of equipment. synthesis and the quality of the product will be car- ried out through physico-chemical characterization with infrared spectroscopy, X-ray difratometry, ther- Development of a Chemical moanalytical techniques and nuclear magnetic reso- 148 Mechanism for the Controlled Release nance in solution and in the solid state. of Bioactive Ingredients for the Microbiological Treatment of the Internal Air in Climatized Atmospheres Obtaining Zinc Coating and Zinc 149 Alloys by Electro-deposition Using Coordinator: Modulated Current, its Passivation via Carlos Alberto Alves de Carvalho Process Devoid of CrVI Followed by Application of Water-based Resin Company: Scientia Tecnologia Química Coordinator: (ex-STQ Ind. e Com. Ltda) Célia Regina Tomachuk dos Santos Catuogno Approved value: Company: Phase 1: R$ 74,797 Tecnozinco Tratamento Superficial Ltda. Phase 2: R$ 244,150 / US$ 4,000 Approved value: The principal focus of this project is in the pro- Phase 1: R$ 61,800 duction of a chemical mechanism for treating con- densed water in air-conditioning systems, aiming for Alloys of zinc with metals from the eighth group the chemical and biological sterilization of the air have been replacing layers of pure zinc in applica- fed back into the internal atmosphere. The mecha- tions which require high resistance to corrosion. As nism of controlled release works by the interaction with zinc coatings, zinc alloys are also chromatized between an encapsulant, cyclodextrine, obtained with subsequent application of a layer of resin. The from a renewable source through a biotechnical pro- project in question proposes to develop layers of cess and hosts with antifungal and/or antibacterial ZnNi, ZnCo and ZnFe electrodeposited using baths action, forming an inclusion compound, which will free from cyanides on a substrate of carbon steel be incorporated into a ceramic matrix. This is an in- using modulated current deposition techniques. novative product, since it differs from other existing Modulated current allows better control of the com- products on the market in its use of controlled relea- position of the alloy deposits, as well as savings in se technology, the mechanism of which is the intelli- the quantity of salts and additives used in the prepa- gent chemical release of the active ingredient which ration of the baths. Subsequently, a post treatment inhibits the multiplication of microorganisms in the will be carried out with alternative products to chro-

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mates, such as molibdates and rare earths and, in re- sent an alternative to traditional agitated vessels, placement for commonly used resins, water-based being able to be used as much in batches as in, prin- varnishes will be researched. The search for alterna- cipally, continuous processes. Nevertheless, there is tive passivants is with the aim of bringing the pro- still a great dearth of methods which permit the pre- ducts up to international standards in terms of envi- setting of specifications for the quality of mixture, in ronmental protection. The efficiency of the process the face of technical limitations in the control of the with modulated current will be compared with the mechanisms which govern its performance. The pre- traditional process through reproducibility, savings sent research proposal aims to establish concepts for on deposition time and chemical compounds, mea- a project for the use of static mixers, optimizing them surements of thickness of layer, the morphology of by means of computer simulation (CFD – computa- the deposit and the composition of the deposition tional fluid dynamics) and validating them by chec- solutions. The resistance to corrosion of passivated king them against experimental data obtained on the coatings will be analyzed with electrochemical tech- workbench, allowing for a mathematical model to be niques: polarization curves and spectroscopy – of drawn up, as well as the definition of extrapolation electrochemical impedance and by in camera expo- criteria for applications on an industrial scale. sure to saline fog. It is intended to develop a mathe- matical model to quantify the protective value of Zn coatings and Zn alloys in a given medium. The per- Obtaining Chelated Pharmaceutical formance of the electrodeposits will be compared 151 and Food Grade Amino with coatings passivated with hexavalent chrome Acids from Natural Sources and organic resins. Coordinator: César Benedito Batistella Design, Simulation and Company: Development of Static 150 Natural Products & Technologies Ltda. Mixers for Liquids Approved value: Coordinator: Phase 1: R$ 65,980 Celso Fernandes Joaquim Junior Phase 2: R$ 209,000 Company: This project aims to develop an adequate metho- KROMA Equipamentos Especiais Ltda. dology for the production of chelated compounds Approved value: from natural sources. The raw materials to be stu- Phase 2: R$ 299,380 died refer to those protein-rich compounds which come from soya, maize and wheat, among others. As With applications in the most varied of sectors, a result, chelated amino acids of iron, copper, cal- such as food, chemicals, pharmaceuticals, or drinks cium, magnesium, cobalt, zinc and manganese will and toiletries, among others, the blending operation be obtained which can be used in replacement for of shaking or mixing fluids plays an important part mineral salts, in relation to which they present seve- in industrial processes, and may be used for a variety ral advantages. Among them, the advantage of cons- of purposes, among which: the mixing of mixable or tituting a more natural product, displaying better unmixable liquids; in the acceleration of heat ex- absorption by the organism and being less toxic. change; to promote the incorporation of solids in li- With a quality of hygiene unquestionably superior quid media; to catalyze chemical reactions; in the to that of commercially produced mineral salts, the- creation of solutions or suspensions. Many concepts se amino acids have great potential for application in of impellers have been created and studied, under a the food, cosmetics and pharmaceutical industries broad range of parameters, aiming, in most cases, to and, naturally to compete in the export market. In meet specific processual requirements. Outstanding addition, with a better technological content after among them are static mixers, devices set up in a line, processing, these raw materials will derive greater provided with mixing elements inserted in a certain aggregated values when they are commercialized. length of tube. The energy used to do the mixing de- The satisfactory results obtained in phase 1 of this rives from the pressure loss generated by the flow of project showed that the proposed production of fluid as it runs through the mixing elements through high-quality chelated amino acids is totally viable. the action of pumping or gravity. Static mixers repre- Phase 2 will complement the first phase, seeking to

Translating Research into Business • 139 overcome the technical difficulties encountered and Design and to transform the methods already developed and 153 Development of Flexible made feasible into productive units. An evaluation Video-Endoscopic of the products will also be carried out in terms of Equipment Using Fiber biodisponibility as mineral source. Optics Consistent with Use in Gastrointestinal Diagnosis and Treatment Production and Commercialization 152 of Equipment for the Coordinator: Electrochemical Removal of Cícero Lívio Omegna de Souza Filho Metallic Ions from Aqueous Effluents Company: Kom Montagens Comércio Ltda. Coordinator: Christiane de Arruda Rodrigues Ragnini Approved value: Phase 1: R$ 62,500 Company: Phase 2: R$ 288,500 Super Zinco Tratamento de Metais Comércio e Indústria Ltda. Upper digestive endoscopy is a procedure which Approved value: permits the mucous membrane of the esophagus, Phase 1: R$ 57,300 / US$ 4,000 stomach and duodenum to be examined in detail Phase 2: R$ 299,519 and represents the most accurate diagnostic me- thod available, with a growing range of therapeutic The central objective of this project is to trans- possibilities. Any symptom that persists or causes form into an industrial process the process of elec- changes in the homeostasis related to the upper di- trochemical removal of metallic ions, developed and gestive tube leads to the carrying out of the digesti- tested on workbenches of the Electrochemical Engi- ve endoscopy. In Unicamp’s Hospital das Clínicas, neering Laboratory in Unicamp’s Faculty of Mecha- 12 per cent of digestive endoscopies had digestive nical Engineering. Based on the results obtained in bleeding as the main indicator for performing the the laboratory, it is intended to design, build and op- examination. The most common causes are peptic timize electrochemical reactors with three-dimen- ulcer and gastric and esophageal varices. The carr- sional electrodes for direct use in the galvanoplasty ying out of an endoscopy is mandatory in all cases industry and others which have heavy metals in their where the bleeding is significant, an endoscopic he- aqueous effluents. The use of the electrochemical mostasis being possible in the great majority. The technique for removal of metals favors the elimi- endoscopic video system proposed by this project is nation, or the substantial reduction, in the iodine technologically innovative in the simplicity of its resulting from the physico-chemical treatment of structure. We will replace the rigid conventional aqueous effluents used in the galvanic industries sec- optical systems with an appropriate fiber optic ca- tor. The proposal for the future is to develop and ins- ble as a conducting element for the images to the tall reactors for the removal of metallic ions in every video system. The resources available will be fewer, water tank used for washing so as to permit the re- when compared to imported devices which offer use of the water in the process, as well as to minimi- ultra high resolution, remote control, electronic ze the amount of aqueous effluents to be treated. To zoom, amongst others, which have grown more so- this end, this project aims to design reactors which phisticated in the course of the world wide spread meet the demand of an industry, bearing in mind of this type of treatment, with technological incre- the speed at which the aqueous waste is generated ments removed from the reality of a country like and the concentration of metallic ions in those solu- Brazil. According to those most informed on the tions. The electrochemical reactors will use three-di- subject, such resources add little therapeutically mensional cathodes and cation membranes dividing and make the commercial price very much higher, the hydraulic flows of the anolyte and the catholyte. around US$ 39 thousand. Once developed, the In addition to the design and selection of materials, equipment should popularize this type of clinical studies will be carried out on the optimization of the examination in Brazil, making it accessible to a lar- speed of the reaction controlled by mass transport ger number of doctors and clinics. and of the distribution of speed and pressure of the fluid on the surface of the electrodes.

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Recording system for Measurements Approved value: of Electrical Energy Transmission Phase 2: R$ 149,963 / US$ 5,288.89 154 of Data to the Concentrator via Communication “Carrier” Mycorrhizas benefit plants directly because they promote an increase in the absorption of nutrients Coordinator: and also indirectly through other mechanisms. The Edison Ramalho increase in the absorption of nutrients is promoted by the external hyphae which derive from the inter- Company: nal colonization of the root system. Arbuscular Qualibras Assistência Técnica mycorrhizas establish themselves in the majority of Dirigida e Comércio Ltda. plants and they are extremely important in natural Approved value: ecosystems, given that mycotrophic plants normally Phase 1: R$ 77,000 are pioneers in areas of low availability of phospho- rus. In agro-systems, plants display good develop- The aim of this project is to build a system for the ment and increased productivity, with lower doses of measurement of electrical energy consumption fertilizer than are normally recommended, when which is very accurate, reliable and operationally ver- they possess good mycorrhizal colonization. Mycor- satile, allowing for the remote programming and ac- rhizal colonization occurs in natural conditions by quisition of data. At present, consumption figures are means of spores, or even hyphae which survive in collected manually, generally once a month. This root segments, left over from previous crops or na- procedure is of low reliability and does not allow for tural vegetation. In the study of the mechanisms of the adoption of a considerable social gain, which mycorrhizal colonization it was observed that some would be the establishment of lower tariffs at specific substances, among them formononetine produced times of the day, that’s to say, the charging of diffe- by the roots and exuded in the rizosphere, stimulate rentiated, more socially fair tariffs. The proposed sys- this process. Following this observation, formono- tem consists of a remote module next to the electro- netine was synthesized in the laboratory. In synthe- nic meter which, via communications carrier, sized form it also stimulates mycorrhizal coloniza- transports the data to the concentrator terminal on tion and therein lies its potential for use as a the post which possesses the transformer for the area stimulant for vegetal development and production. covered. From this point, via transmission through Potassic salt of formononetine also stimulates cell phone, the company’s center of operations col- mycorrhizal colonization and could be simpler to lects the data for processing. With the use of sensors handle than formononetine as it is highly soluble in on the meters, the remote module continually moni- water. The present project aims to demonstrate the tors pulses relating to the consumption of energy. agronomic efficiency of this mycorrhizal stimulant This information is stored in memory units contai- for the cultivation of maize and soya, with economic ned within the modules. The module can be accessed return for the farmer. It is also looking to formulate at any time via cell phone and the data stored in the it adequately for our growing conditions. Four expe- memory units interrogated by specific man-machine riments with maize and four with soya will be car- commands. The centralized computer can even be ti- ried out, with the same guidelines and treatment, metabled to carry out an automatic sweep of all the with the cultivation of soya BRS 133 and maize remote modules of a given urban area and at a pre- hybrid BRS 3060. Further greenhouse experiments programmed date and time. Differential tariffs based will be carried out to gain more detailed knowledge on time of day and day of the week and the month on the interaction of the product with varieties of can be applied by specific programming, recorded in maize and soya and for its application in the organic existing e2prom memory in the remote modules. system of potato and cotton cultivation.

Myconate Automatic 155 Project 156 Vending Machine for the Sale Coordinator: of Natural Juices Eli Sidney Lopes Company: Coordinator: Indústria Bio Soja de Inoculantes Ltda. Enilene de França Cordeiro

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Company: human interventions in order to make them opera- Signalcard Tecnologia Indústria e Comércio Ltda. tional or, even worse, the computer generated solu- tion fails to achieve significant cost reductions when Approved value: compared to manually obtained solutions. This can Phase 1: R$ 53,376 be explained by the fact that these products reprodu- ce the same patterns already employed in the manual The objective is to specify and to design an auto- construction of a travel program. The person nor- matic vending machine for natural juices, especially mally involved in the development of these products orange juice. The machine will have the dimensions has considerable experience in the operation of bus necessary for installation in offices, factories, schools, companies or in the municipal organs of transport hospitals, etc., and one of the main features of this management. However, they have little or no kno- machine will be the fact that it won’t need cleaning, a wledge of computing and the development of mathe- characteristic which will guarantee the quality of the matical models that can be used to tackle this pro- product, independently from the process of distribu- blem. Thus, given the complexity of the problem, tion and maintenance of the machine chosen by the those responsible for the production of the stops fail operator. The machine makes two relevant social to extract, in real time, solutions as competitive as contributions: the increase in nutritional quality for those which could be obtained through mathemati- the machine users, since natural juice is going to re- cal modeling, followed by an automatic generation of place alternatives such as soft drinks, and an increase produced stops using a computer tool implemented in agro-business mainly as it deals with oranges in with a mathematical model base. the State of São Paulo, due to the power of the capil- lary action product distribution in these machines. The machine may also provide an alternative in com- Development of bating unemployment for the small operator, as it Fuel Cells Integrated with demands a low investment and is easy to operate. The 158 Hardware and Software machine will be activated by means of a magnetic for Monitoring, Diagnostics, card. It will be used with a pre-paid card, thus avoi- Control and Peripherals ding the necessity for the installation of a money ma- chine or of an imported banknote reader. Coordinator: Gerhard Ett A Computing Tool Company: 157 for the Programming of Electrocell Ind. e Com. Ltda. Urban Bus Routes Approved value: Phase 1: R$ 62,900 / US$ 6,000 Coordinator: Fernando Antônio Vanini Electrocell proposes to establish the technologi- Company: cal consolidation of a complete package for the de- Fernando Antônio Vanini - ME velopment of a fuel cell with the application of the concept of an intelligent system, incorporating hard- Approved value: ware and software for monitoring, making diagno- Phase 1: R$ 44,604 sis, controlling and simulation software, assuring greater reliability and safety of operation. This pro- The project’s objective is to develop the prototy- ject will assure the strategic development of a project pe of a computing tool capable of automatically ge- for the generation of alternative energy through the nerating trip programs for an urban bus route. In or- use of renewable sources, with the opportunity of der to solve this problem, it begins with a curve technologically consolidating the generation of elec- describing the hourly demand by passengers along trical energy based on the concept of no environ- the route and of a grouping of operational restric- mental harm, principally in urban centers, that is to tions, producing a timetable, as well as the scale of say, through the use of fuel cells associated with the complete service of the buses and drivers/conductors application of hydrogen as a fuel which results in the that are going to operate the urban routes in ques- residue H 0, differing from the type of combustion tion. Some software for this task is already available 2 which produces C0 , the gas mainly responsible for on the market, but the solutions found by them ge- 2 the greenhouse effect. Fuel cells to be developed by nerally end up demanding a considerable quantity of

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the company will be applicable for use in the auto- technical packaging, the insulation of electrical ca- mobile sectors, in residential and industrial buil- bles for applications in the automobile and aeronau- dings and as a source of electrical energy of small tical industries and the cure of adhesives, varnishes wattage for poorer communities and where the na- and paints on different substrates. The proposed tional electrical distribution network finds it diffi- machine aims to generate extended electronic fluxes, cult to reach. The company is proposing the deve- of high current and moderate energy. The underta- lopment of hardware and software for monitoring, king is divided in three phases. The first is the deve- making diagnosis, control and the construction of lopment of a workbench experimental model, con- cells of 1.2 kW fed by hydrogen, fossil fuels and fuels taining the fundamental elements of the project in obtained from renewable sources. Also as part of this order to demonstrate the technical-commercial via- technological package is the supply to the market of bility . The second phase involves the construction of all of the peripherals needed for the use of this sour- a prototype with all the elements of the final equip- ce in the areas of automobiles and the generation ment and which will enable the evaluation of its and distribution of energy. operation within a realistic industrial environment. The third phase will consist essentially of transfer of the technology generated to an industrial base con- Industrial Use templating the mass production of the items develo- 159 Electron Accelerator ped in the present project and the development of national suppliers for its accessory items. Coordinator : José Carlos Orsi Morel Development of a Company: Polymeric System for the Metron - Física Aplicada & 160 Transmission of Light Instrumentação S/C Ltda. Approved value: Coordinator: Phase 1: R$ 59,060 José Miraglia Company: The present project proposes to build an electron Light Tech Ltda accelerator for industrial use in the areas of petro- chemicals, chemical-pharmaceuticals, foods and the Approved value: treatment of effluents. With modern technology, de- Phase 1: RS 75,000 veloped nationally, and which offers reliability, re- duction in costs, minimization of primary and se- Polymeric systems for the transmission of light, condary environmental impact, in addition to offer several advantages compared to glass optical fi- making the technology available to the range of bers. Attempts to use the latter for general or specia- small and medium businesses, which presently are lized lighting have been quite difficult, because these unable to take advantage of it due to serious techni- fibers are expensive, fragile, heavy, have a small dia- cal and commercial barriers. The use of electron ac- meter and do not transmit a large amount of light celerators in industry is fairly widespread in indus- under normal conditions. It is clear therefore, that trialized countries, however, it presents two serious there is a need to find a cheaper, more flexible, lon- problems. The high cost of the equipment and its ger-lasting light source for lighting. And concomi- maintenance and the existence of few suppliers. In tantly, to create polymeric fiber optics resistant to addition to this, the designs of the machines are of ageing, even when exposed to heat of up to 350°C at an old conception – the majority of their patents are the point exposed to the light and up to 250ºC in the from 25 years ago –, they are not very efficient and rest of the length; which offers characteristics such as they consume a great deal of energy, which has ham- good environmental resistance and good light trans- pered the spread of the technology in Brazil. The in- mission property; does not go out of shape with age, dustrial base, however, would benefit greatly from a does not melt, oxidize or deteriorate when exposed broad dissemination of this technology, from the to high temperatures, remaining flexible; and which, point of view of saving foreign currency and the im- besides this, is relatively easy and cheap to produce. provement of environmental conditions, as well as It is intended to apply the technique of radiation-in- the expansion of the possibilities for research and duced polymerization to the system composed of development of new materials, such as, for example, methyl methacrylate monomer base, mixed with

Translating Research into Business • 143 other components to lower the Tg and increase the native system; 5) development of software in high le- flexibility with the aim of: 1) achieving fine control vel language (Delphi); implementation of methods: over the reaction, since radiation polymerization PC-type Microcomputer based on a 32-bit opera- permits greater control of the process, given that the ting system (Windows 95/98 or above). The poten- energy can be delivered directly to the reactive mass tial national market for fluorescence spectrophoto- without problems of heat transmission; it is possible meters with the characteristics described above is to initiate the reaction at any temperature, which al- estimated by the company to be around 40 units per lows for control of every stage, from beginning to year, which equates to R$ 2.4 million. end; and 2) the absence of color, since radiation dis- penses with the use of radicalar indicators. Radia- tion makes it possible to attain higher conversions System of Automatic than in any other process, eliminating the presence 162 Measurement of of monomers that might post-polymerize. the Cornea’s Curvature Rays with a Slit Lamp - Automatic Keratometer with Slit Lamp Fluorescence Spectrophotometer 161 with a Double Monochromatic Coordinator: System of Continuous Liliane Ventura Schiabel Sweeping, Based on Company: a Xenon Pulsating Lamp CALMed Ltda. Coordinator: Approved value: Lídio Kazuo Takayama Phase 1: R$ 53,545 Phase 2: R$ 163,333 Company: Femto Indústria e Comércio de Instrumentos Ltda. The basic objective of the present project is the Approved value: development of a piece of equipment for clinical Phase 1: R$ 52,963 / US$ 4,379.20 use which is simple to operate, but automated and Phase 2: R$ 131,000 precise, which offers measurement of curvature rays of the human cornea, or rather, automatic kerato- In keeping with the world wide trend, the use of metry. This equipment will be adapted to the Split the spectrophotometer in Brazil has been growing in Lamp (ocular biomicroscope available in all oph- volume and importance in the pharmaceutical in- thalmological clinics), and which will be able, at low dustry, molecular biology laboratories, environmen- cost, to carry out quickly the measurements descri- tal control, limnology and the food industry, follo- bed above. The system consists of capturing the re- wing on the heels of a worldwide trend. It also can be flection from the projection of a luminous ring applied in medicine for hormonal analysis and the sight in the patient’s cornea, through an optical sys- demarcation of cancer, in the petrochemical in- tem and a detector of the CCD type. The image of dustry and in the analyses by chemo-luminescence this reflection is sent to a PC type microcomputer and bio-luminescence. Femto’s objectives in this via a video capturing board in real time. The image project are: 1) the development of a fluorescence is analyzed afterwards by a computer program spectrophotometer with double monochromatic which will provide the rays of greater and lesser cur- system of continuous sweep, based on a xenon pul- vature and the respective associated axes, of the sating lamp; 2) knowledge and use of the program analyzed surface, in relation to the deformity of the Optical Design Software ZEMAX -EE(ID) to be ap- reflected image of the ring. In Brazil, manual and plied in the calculation and the optical project; 3) automatic equipment exists for keratometric mea- development of a high speed acquisition system with surements, but it is all imported and expensive. The the resolution of 12 bits or better, with a conversion system proposed here offers, in addition to speed of index less than or equal to 20 ms.; 4) compensation obtaining measurements and the presentation of of the signal by means of the reference beam and the final results, depth of scale up to 30D, precision synchronization through the xenon lamp. Tempori- in ray of curvature and axis comparable to manual zation of the A/D converter should be carried out keratometers, respectively, the advantage of low preferably by the micro-controller 8031, and if this is cost. Phase 1 of the project may be considered a suc- not possible it will be necessary to develop an alter- cess, in view of the enormous interest of other com-

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panies in the sector in commercializing the equip- merizable cements, allowing for the replacement of ment and/or obtaining patent licenses. Thus, in or- the traditional gutta-perch cone. der to cater for clinical needs and market interest, phase 2 will consist of perfecting the system with an LED and also it will be miniaturized. GPS 164 Receiver Development of Coordinator: 163 Photo Conductive Cones Marco Antonio Chamon for the Obturation of Canals Company: with Photopolymerizable Navcon - Navegação e Controle Obturating Material Indústria e Comércio Ltda. Coordinator: Approved value: Luis Augusto Lupato Conrado Phase 1: R$ 61,010 Company: Phase 2: R$ 154,500 / US$ 31,500 Goen3 Comercial Ltda. The enormous growth in the application of Approved value: Global Positioning Systems (GPS) is generating the Phase 1: R$ 41,740 / US$ 10,412.45 need for the mastery of this technology, not only for applications, but also for the adaptation of the pro- Root obturation aims at the complete sealing ject of receptors for specific needs. This need has be- with materials which, through their own properties, come greater in view of the progress in the area of aid the repair process. In view of the large number of low cost inertia sensors, leading to a growth in the endodontic failures, various studies have been car- use of integrated GPS/ Inertia systems. Today this is ried out aiming to optimize the sealing of the root an area of major development in positioning sys- canal. Gutta-perch cone is the solid material most tems in every developed country, and even in some commonly used nowadays for this purpose. This ma- emerging countries. The company, in collaboration terial, however, is unable to fill all the voids pre- with researchers from the National Institute for Spa- viously occupied by the pulp, requiring professionals ce Research, Inpe, is attempting to follow this trend, in the field to use various cements and pastes to cure through carrying out a project developed within the this problem. Owing to the fact that the endodontic ambit of PIPE named Integrated GPS/Inertia Plat- cements used present polymerization by chemical form, now in its final phase. As a natural follow-on, reaction, paste-paste, or even dust-liquid, a mechani- the project now proposes to look into the develop- cal contraction can be observed with consequent in- ment of GPS receptors based on available chips sets. filtration next to the wall of the root canal. On the The objective is, through the mastery of the project’s other hand, photopolymerized cements display qua- techniques, to eliminate restrictions imposed in the lities superior to those chemically activated, but they use of the receptors in applications of greater altitu- are not indicated for endodontics owing to the diffi- de and speed, such as space, as well as to permit an culty of guiding the light to the apical region. The improvement in the use of the techniques of integra- possibility of guiding laser light by optical fiber to the tion with inertia sensors and others. The restrictions apice permits the testing of the apical sealant using mentioned previously are not found in the chip set photopolymerizable cements. Faced with the diffi- used for the receiver, but in the software firmware culties imposed by a common optical fiber for this which determines the dynamic of the tracking cove- type of application, a solution adapted to this kind of rage of the satellite signals and, therefore, the capa- optical device was sought. It involves the design for city to track a vehicle with greater velocity and acce- creating a photoconductive cone capable of distribu- leration, and in the application software which ting optical radiation along the whole length of the determines the vehicle’s coordinates. This software root canal. For the construction of this device the can be altered once the algorithms involved are mas- characteristics of different biocompatible polymeric tered. The possibility of using a GPS receiver with materials will be studied, for subsequent develop- several aerials, or several GPS receivers for the deter- ment of the process of obtaining the cone. The im- mination of altitude received a great boost recently plementation of this device will enable the complete when it became possible to obtain greater precision sealing of the root canal with the help of photopoly- from the systems using low cost inert sensors,

Translating Research into Business • 145 through their operative calibration. In a project de- trological characteristics of the instrument pre- veloped by the previously mentioned company, this viously measured. The implementation of this pro- last option was used. By means of access to the de- ject should significantly reduce the time and total sign of the receiver, consideration of the second op- cost of the calibration of audiometers, permitting tion becomes a possibility, particularly for space ap- the metrological laboratory to function far from its plications, in which the reduction in weight and base, while nevertheless maintaining a high degree energy used is more important than cost. of reliability in its measurements.

The Establishment of Development of 165 a Metrological Standard for 166 a Tar Based Resin with an Audiometric System Enhanced Properties for Use with Parameters for the in the Graphics Industry Respective Functions of Calibration and Reliability Coordinator: Paulo Firmino Moreira Junior Coordinator: Company: Oswaldo Rossi Júnior Angatuba Química Ltda. Company: Approved value: Inter-Medtro Serviços Phase 1: R$ 40,100 Especiais e Consultoria Ltda. Phase 2: R$ 233,800 Approved value: Phase 1: R$ 5,500 The objective of the present work is to design a Phase 2: R$ 77,480 process for the production of resins with enhanced characteristics for use in the graphics industry which The carrying out of an audiometric evaluation is are in the public domain or innovatory, and the pro- extremely important in the process of diagnosing duct of which possesses properties appropriate for individuals suspected of having a hearing problem. use as a pigment vehicle in off-set printing presses. Electronic equipment called audiometers is used for Brazil is the world’s second largest producer of tar. this purpose. However, two factors conspire negati- However, the national industry does not add suffi- vely to influence and drastically undermine tests cient value to this raw material, which is exported carried out in this country. The first is the lack of a and later imported back in the form of finished pro- national standard for the metrological reliability of duct. Currently the company also produces tar based the equipment, along with the occurrence of a very resins with a low added value due to the use of an large number of diverse equipment and distinct me- outdated technology. The project includes the dra- thodologies. Secondly, the lack of standardized pa- wing up of a bibliography involving the study of pa- rameters and metrological standards for these pie- tents and papers for the selection of possible routes ces of equipment. The central objective of the of synthesis for the definition of raw materials to be present project is to develop research and define sta- used in the second stage. Trials are also planned in ble standards for the operating of audiometric sta- the Analytical Center of the Chemical Institute of tions in their diverse configurations, as well as stan- the University of São Paulo, USP, and reactor bench dards for the metrological reliability of these trials in USP’s Department of Chemical Engineering stations. It is about developing a brand new and re- with a view to obtaining a first selection of process liable system of measurement for analysis from au- conditions, including in this operating conditions diometers with characteristics such as operational (temperature and pressure) and the proportion of agility and portability that may be removed from reagents to be fed in with the aim of synthesizing a the metrological laboratory to clinics and locations resin with the desired characteristics, enabling an as- where audiometric tests are being carried out. In sessment of the technical-economic viability of the this way, the system will be able to carry out rea- synthesis. In the second phase, in addition to the de- dings and measurements in a simple manner and in velopment of tar based resins with enhanced proper- real conditions. The readings effected will be stored ties for use in the graphics industry, the implemen- in electronic memories (loggers) and sent to the la- tation of a structure for the engineering of tar based boratory for analysis and the definition of the me- products will be emphasized.

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The Production of LF Amino Acid Chelates from Line Project 167 Hydrolyzed Proteid of 168 Saccharomyces cerevisiae Coordinator: to be Used as Mineral Food Vicente de Paula Barbosa Supplements of High Bio-Availability Company: Lifemed Industrial de Equipamentos Coordinator: e Artigos Médicos e Hospitalares Ltda. Ricardo da Silva Sercheli Approved value: Company: Phase 2: R$ 173,947 / US$ 7,400 Biofarm Química e Farmacêutica Ltda. Approved value: The vast majority of infusions are performed by Phase 1: R$ 61,840 gravitational means, an inadequate method in view Phase 2: R$ 216,190 / US$ 255,275.20 of the need for constant readjustments in the flow as the level of the liquid to be infused decreases in the The goal is to develop processes aimed at the feeder bottles as the infusion progresses. With the industrial production of chelates of amino acids ob- introduction of new, more concentrated and power- tained through complexation reactions between dif- ful drugs, requiring stable and precise flow for the ferent metals and the hydrolyzed proteid of Saccha- safety of the patient and the medical profession, so- romyces cerevisiae. Stage 1: Hydrolyzed proteid of called mechanized infusions have emerged. These Saccharomyces cerevisiae: though amply described in use micro-processed electro-medical pieces of technical literature, the research intends to develop equipment which control in a precise and constant an industrial process capable of obtaining a hydroly- manner the amount of medication injected. During zed product of the necessary quality to be used in the these sessions, the infusion line must be monitored next stage, at a competitive operational cost, avoiding for the presence of air to prevent patient embolism the generation of effluents. The two selected proces- and also the occurrence of excessive pressures which ses for the study were that of acid hydrolysis and of could cause a break in the line or in access to the cir- enzyme hydrolysis: a) acid hydrolysis: the work will culatory system. In addition to this, medical staff initially concentrate on the parameters described in need to be alerted by the equipment via its alarm the literature, aiming for an optimization of the pro- systems in case the medication runs out or the line cess in relation to the different acids used; b) enzyme in becomes obstructed. The proposal for this project hydrolysis: will be conducted in the presence of a is to develop items of equipment essential for the mixture of proteids, initially following the data des- medical practice of life support. The equipment set cribed in the literature for posterior determination of brings together the following features: 1) a linear pe- the operational parameters of the process. The choi- ristaltic pump – the first such equipment to be ma- ce of the best process will be made based on the qua- nufactured in Brazil using national technology; 2) lity and cost of the hydrolysis obtained. Stage 2: ami- an “air-in-line” detector using proportional ultra- no acid chelates. These will be obtained by adopting sound; 3) non-invasive infusion line detector; 4) ac- the following steps: a) the formation of organo-me- tivation of system peristaltic linear system by means tallic complexes; b) desalinization of the mother li- of a micro-controlled stepper motor with variable quid of the reaction and the isolation of the product; torque; 5) anti-free-flow device which cuts off the c) the drying of the complex. Phase 2 of the project flow; 6) infrared system for the detection of dripping will seek, taking into account the results obtained in and end of infusion; 7) patient alarm and protection phase 1 and works described in the literature, to de- systems; 8) interactive user communication and velop processes aimed at the industrial production of programming via LCD; and 9) micro-controlled au- free amino acid chelates and peptides obtained tomatic test routine for detectors and audible and through complexation reactions between different visual equipment signals. metals and the hydrolyzed proteid of Saccharomyces cerevisiae. The proposal is to obtain a hydrolyzed proteid containing peptides with a molecular weight Thermo-chemical and Plasma of half 1 million daltons, which offer high absorption 169 Treatment of Carbon Steel Reels for the organism. Coordinator: Vladimir Henrique Baggio Scheid

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COMPANY: This project seeks to develop finished polyether Metal Plasma S/C Ltda silil-based adhesives and sealants for use in industry and civil engineering. This involves an important Approved value: technological innovation in the science and enginee- Phase 1: R$ 21,710 / US$ 2,115 ring of polymeric materials, since they have adhesive properties equal to or superior to silicone and polyu- Nitration by plasma is a process used for the im- rethane adhesives in almost all substrates used in in- provement of various physical properties of steels dustry and civil engineering. Unlike other types of such as hardness and resistance to wear, corrosion adhesive, they are free from solvents and isocyanates, and fatigue. This process consists of a luminescent being, therefore, harmless to the atmosphere and to discharge of gases at low pressure containing nitro- the health of workers. They also form resistant and gen. The plasma makes use of nitrogen atoms that quick-setting bonds, which should encourage new permeate into the steel to form nitrides of elevated production methods in industry and civil enginee- hardness. In this process there is no formation of ring. The project will determine the formulations pollutant residues. Especially in the case of carbon which best suit the needs of the national market for steels, the nitration favors a definite and long lasting adhesives and sealants. The physico-chemical pro- protection against corrosion. The objective of this perties of the formulations obtained will be optimi- project is to develop a process for the treatment of zed and compared with silicone and polyurethane carbon steel reels through their cleaning and nitra- based products currently used on the market. At this tion by plasma, with a view to protecting them from stage, the basic production processes of the most sui- corrosion. The intention is to develop the process table formulations will be determined and tests car- and to improve on the parameters in order to reach ried out in pilot batches using potential customers. a compatible cost and higher standard of quality Once the product and process parameters have been than those offered today by galvanoplasty. It is also defined, the intention is to produce and commercia- proposed to carry out market research among the lize those products which demonstrate the best cost- large suppliers and users with the aim of evaluating benefit relationship and market potential. the demand and the requirements of each line of production. Though commercial equipment exists, capable of processing a large quantity of material, it 9th BIDDING INSTRUCTIONS is not appropriate for the treatment of reels of sheet metal and wires, since only the external parts of them, which are exposed to the plasma treatment, Development of are nitrated. The present process, using an innovati- Expander Agent ve system, would permit the nitration of long reels of 171 Based on Aluminum wire. Its development will enable the company to in- Slag for the Production crease its area of activity and will also bring socioe- of Autoclaved or Molded conomic benefits, both from the environmental Cellular Concretes in loco point of view and in the generation of new jobs. Coordinator: Edval Gonçalves de Araújo Finished Polyether 170 Silil-based Adhesives and Company: Sealants for use in Industry Siporex Concreto Celular Ltda. and Civil Engineering Approved value: Phase 1: R$ 72,700 Coordinator: Phase 2: R$ 300,163 Wang Shu Chen Company: Secondary slag from the production of alumi- AdEspec Adesivos Especiais num contains, in addition to oxides, salts and other Ind. e Com. Import. e Export. compounds, around 3 to 5 per cent of metallic alu- minum. After processing the slag, the removal of the Approved value: salts takes place and a powder is obtained with a Phase 1: R$ 44,830 / US$ 3,690 granulometry below 150 micrometers. The resulting Phase 2: R$ 291,000 material contains aluminum metal finely spread and

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homogeneously dispersed. When exposed to the al- conditions of this process will allow a technical eva- kaline medium, it releases hydrogen and can be used luation to be undertaken and, subsequently deter- in the production of cellular concrete. The experi- mine the economic viability of the project. ments in this project aim to determine the proper- ties of autoclaved cellular concrete with the addition of slag as a gas forming agent (apparent dry density Safety Culture in – NBR 13440 – and resistance to compression – NBR 173 Activities Involving 13439), maintaining the same industrial conditions Ionizing Radiation of the processing. Concrete not autoclaved with slag, will be tested for the action of stabilizers and ten- Coordinator: soactives on the resistance to compression of concre- Gian Maria Agostino Angelo Sordi tes with a density of 800 to 1600 kg/m3 (NBR 5739). Company: Thus, this project is based on the reuse of a highly Átomo Radioproteção e polluting industrial waste in the production of cellu- Segurança Nuclear S/C Ltda. lar concrete. In financial terms, this technique repre- sents a viable alternative for the replacement of com- Approved value: mon expanders (aluminum powder or foaming Phase 2: R$ 250,400 / US$ 895 agents), decreasing in up to 10 per cent the cost of raw material used in the manufacture of these two The company offers radioprotection services in types of concrete. the field of ionizing radiation applications in indus- tries, in the area of medicine and in research, among other sectors. To achieve part of its objectives, Áto- Instant Whole Bean: mo developed an educational sector which, among 172 Study of the Critical other products, provides interested parties with the Conditions in the Process minimum knowledge that a specialist in radiopro- tection or a worker should have, in the presence of Coordinator: ionizing radiation, to carry out their tasks with sa- Franz Salces Ruiz fety. The learning system currently in place amounts to an exposition by the instructor and the clarifica- Company: tion of the pupil’s doubts, which, in addition to Green Technologies, Projetos being expensive, removes the specialized professio- Agroindustriais S/C Ltda. nal from the workplace for a minimum of five Approved value: weeks. The objective of this project is to develop a Phase 1: R$ 17,991 low cost multimedia course, which can be followed at a distance, with or without the presence of an ins- Owing to the complexity of modern life, the tructor, in a group or individually. The course could spread of so-called convenience products – foods have different degrees of complexity, that’s to say, it which combine speed with ease of preparation – has could be accessed by the simplest or the most so- become ever more widespread. The development of phisticated pieces of equipment. The company’s instant whole beans was based on growing demand mission, in this business, is to offer flexibility of so- from that market and considering that Brazil is the lutions, using techniques which afford the least world’s leading producer and consumer of this im- physical and emotional wear on the professional, as portant legume. Instant beans benefit from the high well as lower costs for the business that uses them. availability of excellent quality raw materials, easily adaptable technology, low energy consumption and high yield. In view of this, to industrialize this type Malleable Pleated Valve with of bean, technico-economic viability studies are 174 Self-Adjustable Flow Mechanism needed. Based on the methodology described in the for Pleural or Mediastinal product patent’s technical statement, the objective Drainage Collection System of this first phase of the project is to determine the critical conditions of the parameters in the unitary Coordinator: operations considered most important in the pro- Hugo David Chirinos Collantes cess, in the maceration with mineral salts and in the Company: high pressure heat treatment. The study of these Roberto de Menezes Lyra ME.

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Approved value: which makes it very attractive in refuse situations in Phase 1: R$ 47,000 the environment. This polymer is also biocompati- Phase 2: R$ 140,000 ble, with a high regularity of polymeric chain and high molecular weight, which permits numerous in- At the moment, public hospitals in remote parts dustrial applications, including flexible packaging of Brazil use systems for pleural and mediastinal (films), rigid packaging (blown bottles, plastic bottle drainage which are fashioned by the surgeons’ own tops and thermoforming sheets) and surgical com- handicraft. These systems can cause serious compli- ponents, among others. The biodegradable plastic cations in the patient’s convalescence, raising the risk PHB (polyhidroxibutirate) synthesized by biotech- of hospital infections and of post-operative sequels. nological production is extremely competitive com- On the other hand, the systems for pleural and me- mercially, since starting with cane sugar, with the diastinal drainage with a simple or single collecting stages of synthesis, extraction and purification of the bottle, manufactured on an industrial scale in Brazil, polymer with natural solvents, a final product with a promote improvement in the quality of hospital care, very low cost is obtained. The present project aims to at a relatively low cost when compared with interna- launch this product on the plastic packaging market. tional products. The innovation in this product is a In order to characterize and formulate the polymer, malleable pleated valve with a siphoning mechanism it will be necessary to acquire some basic equipment self-adjusting for flow. At a low cost, this product in polymer technology which will go towards com- adds technology to the system for pleural and me- plementing the investments already made by PHB diastinal drainage with a simple or single collecting Industrial S/A in this project. bottle, making it more competitive technologically. This valve will optimize the variations in subaquatic pressure drawn off by siphoning the gases coming Production of from the thoracic cavity, in the collecting system. In 176 Pre-alloyed Metal Powders the technical viability stage of the project, the matri- by Atomization for ces and the manufacturing processes for the pieces Application in the Manufacture that make up part of the drainage system were deve- of Tablets for Addition of loped. In the second phase, the manufacture of the Alloying Elements in pleated valve which is part of this system will be op- Aluminum Metal Baths timized, concentrating on the choice of materials which are totally sterilizable by ionizing radiation. Coordinator: Lucio Salgado Company: Production and Characterization Mextra Engenharia Extrativa de Metais Ltda. 175 of Environmentally Degradable Polymers (EDP) From Approved value: Renewable Sources: Sugar Cane Phase 1: R$ 73,600 Phase 2: R$ 300,000 Coordinator: Jefter Fernandes do Nascimento The addition of alloying elements in metal baths can be achieved using carriers contained in the mo- Company: ther alloys obtained by smelting or, as is becoming PHB Industrial S.A more widely used, by means of powder mixtures, in Approved value: the form of tablets or briquettes. In the specific case of Phase 1: R$ 54,360 aluminum alloys, normally mixtures of aluminum Phase 2: R$ 284,480 powder are used with powders of the alloying element one wishes to add, such as iron, chrome, nickel, cop- Poly(3-hydroxybutyric acid) or pl-113 is an envi- per, manganese, etc. These tablets must perform well ronmentally biodegradable polymer, synthesized in the dissolution of the alloying element, that is, they and accumulated as a reserve substance by a series of must provide a good yield so that as much as possible bacteria, with thermoplastic properties similar to of the alloying element is incorporated into the liquid those of conventional polymers. However, it mani- aluminum. This project aims to develop the process fests the peculiarity of being highly biodegradable for manufacturing powders of metal alloys by water when exposed to biologically active environments, atomization, the main purpose of which is the pro-

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duction of these tablets. The idea is to add value to the Control Network of Devices with tablets by means of manufacturing a powder with the 178 Distributed Intelligence with Voice final desired composition, normally in the range of 70 and Data Communications Interfaces to 90 per cent of the alloying element (the remainder with Public Exchange Telephone aluminum), which could minimize or dispense alto- Lines, Applied to Residential, gether with the use of elemental powders. In phase 1 Commercial, Industrial Automation of the project the atomization parameters were defi- ned for the preparation of the metal alloys. Phase 2 is Coordinator: planning to install an industrial unit with capacity for Miguel dos Santos Alves Filho the production of 200 tons per month of the Fe- Company: 10%AI alloy. In this phase, studies will be carried out Conceito Tecnologia Ltda. to optimize the manufacturing process of the powder and the tablets. Approved value: Phase 1: R$ 56,273 Phase 2: R$ 121,035 Interphone 177 Communication System The fundamental objective of this project is to via Electricity Network demonstrate and implement a new applied techno- logy in telephony. This technology distributes intelli- Coordinator: gence and autonomy through a communications Manuel Bernardo da Silva Neto network by means of interfaces for the participating telephonic circuits of any telephone system to share Company: and inter-relate all the internal and external states to EQE - Eletrônica Qualificada Espacial Ltda. be controlled by a communications network special- Approved value: ly developed for this purpose. The technology displays Phase 1: R$ 35,120 high performance, with speed in the interoperability of all the components of the network. In addition, The central aim of this work is to validate the the control of the process is entirely decentralized. concepts and ideas for the development and imple- Each active element or sensor works independently mentation of an interphone system for condomi- while being at the same time integrated to the other nium environments using the electric cabling as a devices present in the network. The main advantage means of propagating the voice signals. In this way of the system is low amount of wiring and cabling and the need for the installation of a specific new me- it can be applied in a modular manner, decreasing dium for communication between the terminals is maintenance costs. Telecommunications, residential dispensed with, as is the need for a central routing automation, commercial and industrial sectors are unit. The basic objective is to make available a solu- the targets initially envisaged for the application of tion to meet the needs of users who do not have an this system. The present project is studying the me- efficient means of communication amongst them- thodology and modeling for the development of any selves, or which represents an important safety item. control system based on the concept of distributed Or to cater for those who live in environments whe- network control, in any field of application. re the installation of currently available systems is difficult or costly. Technically each interphone will be an independent terminal, capable of entering or iGate - Gateway with Direct leaving the network environment without impairing 179 Connection to the Internet it. To guarantee secrecy and reliability in the com- munication or in the establishment of the link, some Coordinator: sort of spectral diffuser will be used, adding to this Marcelo Tadeu Bertanha product a modern technology, which will allow for Company: an expansion of functions. We will also make availa- IAS - Integração e Automação de Sistemas Ltda. ble a low cost, flexible and secure alternative means of closed network communication. Approved value: Phase 1: R$ 51,936 / US$ 1,200 Phase 2: R$ 184,145.29

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This project entails the development of a piece of cing processing time and improving the quality and hardware called i-gate, the function of which is to stability of the results. A parallelized algorithm mo- collect field variables such as level, temperature, del will be implemented (own code/optimization flow, pressure and other so-called field variables. The solvers), parameterized for the number of CPUs. hardware connects directly to the world wide web The computational architecture used will be a uploading information there into a database, acces- workstation with various processors, compilers and sed by software developed for the internet environ- a set of optimization solvers. In the second phase, ment. I-gate will have the main capability of moni- complex operational restrictions will be incorpora- toring up to eight field variables, isolated from the ted such as, for example, a large number of products, existing measuring provision, with a weatherproof different packaging, different vehicles and time win- cabinet, and two digital input and output connec- dows for collection and delivery. Optimization of tions. The main benefits envisaged derive from the stock replenishment will also be modeled, aiming to use of the existing web structure, rendering unneces- program deliveries/collections so as to simulta- sary a structure for receiving the information, or a neously optimize transport costs and stock costs. Datacenter. With a local connection to an internet service provider, long distance calls will no longer be necessary. Equipment imported today does not have Development of a Low Cost a direct connection to the internet. I-gate, presently, 181 System for the Generation of a is applied in the Remote Monitoring of Tanks for the Differential Correction Signal, supply of grain. The product supplier receives infor- in Real Time, for GPS mation regarding levels in the tanks via internet, from his customer, and carries out a Planned Pro- Coordinator: duct Delivery, based on demand, production, trans- Nelson Luis Cappelli port conditions and other parameters. Company: DLG Automação Industrial Ltda. Application of Parallel Approved value: 180 ComputingTechniques to the Phase 1: R$ 39,145 Solution of Problems in Phase 2: R$ 226,470 the Logistical Optimization This project aims to develop a low cost system for Coordinator : generating differential correction signals for GPS Nelson Bianco Standerski (global positioning system) in real time, with radio- frequency transmission and use of a private correc- Company: tion station. For the development of this station it is Paperless Consultoria e Serviços em Sistemas intended to use a GPS receiver of the portable type to de Gerenciamento de Informação Ltda. generate the correction signal. GPS is, at present, the Approved value: most widely spread and used global positioning sys- Phase 1: R$ 7,500 tem. Low cost GPS receivers, used by civilians, cur- Phase 2: R$ 22,460 rently display an inaccuracy of 15 meters in horizon- tal positioning. To improve the GPS accuracy, The project aims to develop a set of software so-called “differential correction” can be used, this tools for application in large scale problems of logis- being the system known as Differential Global Posi- tical optimization, using parallel processing techni- tioning System (DGPS) or differential GPS. The ques. The first phase seeks to demonstrate that the functioning of DGPS is based on the supposition algorithms of parallel processing can be successfully that the error in determining a point is similar for all applied in this area, in the typical operating condi- the receivers situated in a radius of up to hundreds of tions that exist in Brazil. The generation of the pro- kilometers. The elimination of this error allows the gramming of deliveries/collections in the case of a user to significantly reduce the total error present. large number of places of origin and destination, With the use of differential GPS the precision in po- freight with different characteristics, large and diver- sitioning can increase up to submetric figures. It will sified fleets of vehicles and the needs of replenishing be necessary to develop a piece of equipment that stocks is a large scale inventory routing problem. Pa- will receive the GPS positioning signal and transform rallel programming can help in its solution, redu- it into correction signal in the appropriate format.

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Industrialization of The creation of solutions for the diagnosis of gas- 182 Biodegradable Starch Films troesophagal reflux diseases (DRGE) is the origin of the present proposal. Studying the clinical manifesta- Coordinator: tions of these diseases, physiological aspects of the Olivier François Vilpoux human body and the digestive process, the search is for technological concepts for the monitoring of eso- Company: phagal reflux and esophagal motility. The idea is to Empresa de Materiais Biodegradáveis develop a piece of equipment which, by means of a Indústria e Comércio Ltda. probe inserted in the esophagal cavity, parameterizes Approved value: the physical modification in the region during a de- Phase 1: R$ 44,115 termined period. The probe will store the alterations Phase 2: R$ 151,200 of the pH and the pressure exerted by the esophagus musculature, which will be transferred to a piece of The project aims to identify industrial equip- software which will interpret in numbers, graphics ment and the adaptation of biodegradable starch and statistics the data collected, comparing it with films to enable their large scale production. The in- pre-established data. This measuring apparatus tention of Empresa de Materiais Biodegradáveis should reach a broader range of pH reading, making (EMB) is to produce biodegradable matter based on it possible to identify the origin of the reflux. The starch and other materials of vegetable origin. Starch probe should have multiple sensors, which will per- film is already suited to niche markets such as edible mit more accurate and faster monitoring. In the rea- wrappings (sweets, candies and toffees) or for packa- ding of manometric pressure, for example, the mul- ging of products to be dissolved in water (detergent, tiplicity of sensors will be better at interpreting the defensives and chemical products). However, the sequences and pre-established standards of the beha- equipment for the manufacture of disposable plastic viors of the esophagal motility. Owing to the cost of films on the market has not adapted to the starch imported apparatus, the pH/manometric examina- film, mainly as it uses cooling for hardening, while tions are not very widespread in Brazil. The produc- the starch demands a drying process. As well as the tion of a national apparatus, at an accessible cost, will differences in the processing stages, the raw material bring great social benefits to the country. that gives origin to the starch film has a consistency different from the plastic one, making the process of blowing and film formation difficult. In the first Preparation of phase of the project, in which work was done on the 184 Magnesium Hydroxide identification and evaluation of possible equipment as Antiflame in Polymers that could be used for the formation of starch films, among other activities, problems were uncovered Coordinator: that need to be solved in the second stage. The inten- Pompeu Pereira de Abreu Filho tion is also, in this phase, to carry out impermeabi- lity tests on the products and on the materials obtai- Company: ned from EMB’s pilot equipment, in addition to Itatex Indústria, Comércio de Cerâmica Ltda. working on the improvement of the mechanical pro- Approved value: perties of the film, and on the preparation of a detai- Phase 1: R$ 54,823 / US$ 7,995 led business plan. The project involves the development of an ori- ginal chemical process for the preparation of mag- Project for Monitoring Equipment for nesium hydroxide to be used as an antiflame pro- Gastroesophagal Reflux Disease (DRGE) 183 duct in polymer compounds. The starting materials with Innovative Use in Biliar Paths will be commercially available natural magnesite or caustic magnesite (MgO). If the starting material is Coordinator: magnesite, the chemical process will entail its ther- Paulo Sakai mic decomposition using formed briquettes with Company: hollow perforations in one of their extensions and Ibasil Tecnologia Ltda prepared mixing magnesite and water, in the presen- Approved value: ce and in the absence of an organic agglutinant (dex- Phase 1: R$ 42,360 trine). These briquettes must be mechanically resis-

Translating Research into Business • 153 tant to withstand the manipulations and contraction such as working in proprietary environments, lack of stresses during thermal treatments. The magnesite access to external sources of content, and non-reusa- briquettes will be transformed into caustic magnesia bility of modules and content, among others. The by thermal decomposition (between 600-800ºC) in product proposed here is innovative because it adopts an oven with forced air renovation and, immedia- advanced technologies, such as the use of the 3-tier tely, ground to obtain caustic magnesia in the form model of development, EJB specification platform, of powder. If the starting material is commercially which promotes the re-use and rapid integration of obtained caustic magnesia, the chemical process will components, adoption of Java language, with interac- not include the stages of briquetage and thermal de- tions with databases via JDBC, use of XML language composition and will begin at the hydration stage. In to support access to databases of external and hetero- this stage, the caustic magnesia in the form of pow- geneous content, and the use of GPL (general public der will react with water vapor in the interior of a license) tools in the environment. The product reactor built for this purpose. The reaction of the will be developed in the context of open source. Since caustic magnesia plus the water vapor producing it will be built in the form of components, new func- magnesium hydroxide will be monitored using ther- tionalities will easily be added to the product, which mogravimetry and/or x-ray diffraction to determine makes it flexible and easy to integrate. the fractions of magnesium hydroxide formed and caustic magnesia remaining during the reaction pro- cess. The starting materials and the magnesium Diagnostic Kit for hydroxide will be characterized physico-chemically 186 Potentially Deteriorating by instrumental methods and by humid method. Micro-organisms Chemical composition, specific surface area, chemi- cal reactivity, density and granulometry will be de- Coordinator: termined. Crystalline structures and degrees of Soelly Magalhães do Valle crystallinity will be determined by x-ray diffraction. Company: The variables of each stage of the process will, when Tecxhall Tecnologia Ltda. necessary, have their effect studied by chemiometric techniques. The results obtained will be analyzed to Approved value: verify the technical and economic viability of the Phase 1: R$ 61,590 / US$ 5,000 process in the production of magnesium hydroxide on an industrial scale. Micro-organisms play an important role in the bio-deterioration of materials and, in a general way, in industrial processes. Some examples: the presence Editing and of algae, strong odors, stains, unexpected fermentati- 185 Publication System ve processes, among others. What’s serious is that in- for the WWW dustries only manage to detect the problems of bio- contamination when all is lost, because there is no Coordinator: fast, safe, economic and efficient control to indicate Rodrigo Fernandes de Mello that the situation is at green (bio-contamination un- der control), yellow (biocontamination in state of Company: alert), or red (bio-contamination at dangerous le- Radium Systems Ltda. vels). At present the service for controlling industrial Approved value: bio-contamination is effected through complicated Phase 1: R$ 48,000 and expensive techniques. The present project pro- poses the use of diagnostic kits to monitor bio-con- The objective of this project is the research and tamination in industrial systems, in products and implementation of an innovative product for editing raw materials. The project for the development of and publication on the World Wide Web on a large analyses of biodeteriorating bacteria in kit will confer scale, while reducing time and costs. The production the following advantages: efficiency, practicality, of content for the Web, whether in the form of trai- speed, economy and above all safety for the health of ning courses, distance learning or journalistic sites, the operator and of the environment. In addition to has a high cost and a large preparation time. The nu- the safety of the integrity of the kit itself, since one of merous editorial and content publication products the great problems of laboratory techniques is the existing in today’s market have various limitations, fact that external microbiological contaminations

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occur which could conspire to mask the results. The Company: realization of the project will help businesses and go- Global Eletroquímica Ind. e Com. de Metais Ltda. vernment to gain access to fundamental information, Approved value: which is presently difficult to ascertain and control. Phase 1: R$ 70,000.00

In Brazil, lead mines are practically exhausted Preparing Future and the sub-products which contain compounds of Entrepreneurs 187 this metal (concentrations of lead) generated by the mining industries of other metals have been expor- Coordinator: ted. Consequently, the lead metal required for the Valéria Maria Barros de Andrade manufacture of lead-acid automotive batteries has Company: been supplied by imports and by the recycling of Desenvolvimento e Tecnologia dead batteries in national metallurgy plants. The Mentortec Ltda. (Red Tecnologia S/C Ltda.) present project aims to develop and implement the electrohydrometallurgical process as an economical Approved value: and environmentally appropriate alternative for the Phase 1: R$ 39,200 recovery of lead metal, initially from a residue rich in Phase 2: R$ 190,460 lead compounds, and in the future, from other raw materials, such as scrap lead-acid automotive batte- The objective of the project is to develop a piece ries, lead mines (mainly galena) and from residues of software with an interactive learning environ- or effluents which contain lead compounds. By this ment aimed at future entrepreneurs. Its focus is to process, the lead compounds contained in the resi- give guidance in an objective and integrated man- due will first be converted in lead sulfate. Following ner on the structuring of a technology-based pro- the lixiviation of the lead sulfate, lead metal of high ject, transforming ideas into business. The applica- purity (99.99 per cent) and easily commerciable will tion was structured in four units which touch on be electrodeposited on a stainless steel cathode con- and demonstrate the interconnection that exists tained in an electrochemical reactor. between the following topics: Strategic Thinking, Product Conception, Business Plan and Financial Support. It possesses innovative characteristics: 1) Methodology of Online Integration of the concepts Strategy x Product De- Teaching Applied to Courses velopment x Business X Resources via an interacti- 189 Geared to Information Technology ve environment which prioritizes critical thought, the end result of which will be a decision taken on Coordinator: the make-up of the business, as well as on the credit Armando Fernandes da Silva Moreira agreement; 2) Ability to make intimate associations with the user’s reality and analyzing potentialities Company: and risks; 3) Adaptation of content according to the People BrasilEducação Ltda. user profile at the time of execution, that’s to say, Approved value: the user can choose cases from his specific area and Phase 1: R$ 50,355.00 / US$ 7,000.00 the environment will be automatically reconfigured to display the chronological path through the envi- The objective of this research is the development ronment related to the case selected. As the main of a methodology for e-Learning which enables the form of distributing this application, the Entrepre- production of courses mediated by computer, geared neur’s Portal will be set up, which will permit the to Technology Information. The research takes ad- offer of additional services with specialized tutorials vantage of the developmental atmosphere of a busi- and a discussion forum among others. ness and part of its methodology for the production of its in-person courses to adapt and transpose its components to the model of distance courses and Recovery of Lead Metal by an educational programs that will be implemented. The Electrohydrometallurgical Process 188 project defines the methodology of online teaching and orientation documents for the author, for the Coordinator: teacher and for the students. As a practical test of the Abel Edmundo Chacon Sanhueza theoretical bases, the project develops an online pi-

Translating Research into Business • 155 lot course on Basic Programming Logic for applica- microprocessors. Experiments will be carried out to tion to a group of students in public and private verify the effect of high intensity current transitories schools in Campinas. Using this pilot course a tool on the calibration of the transducers. Immediately for online course management will also be tested. after, the possible methods of correction such as de- magnetization, will be investigated. Finally, some studies on the effects of mechanical cuts on the mag- Development of netic properties of the nuclei will be investigated. 190 High Accuracy Current Transducers with Microprocessed Re-excitement Mesh Photovoltaic generators 191 for Aerospace Applications Coordinator: Carlos Shiniti Muranaka Coordinator: Célio Costa Vaz Company: Globalmag Transdutores Magnéticos Company: Indústria e Comércio Ltda. Orbital Engenharia Ltda. Approved value: Approved value: Phase 1: R$ 22,600.00 / US$ 2,725.00 Phase 1: R$ 39,000.00 Phase 2: R$ 70,650.00 Phase 2: R$ 197,700.00 / US$ 45,313.56

This project proposes to identify magnetic mate- Photovoltaic generators were and continue to be rials, cutting methods, heat treatments, detection the most attractive form of energy generation for ae- and control systems which will enable the construc- rospace applications. Proof of this is the accelerated tion of high accuracy and low cost AC/DC current technological development witnessed in the last deca- transducers. For current detection, commercial des of their basic components and assembly processes. magnetic field sensors will be evaluated (for Hall or The objective of this project is the development and magnetoresistive effect). Various magnetic materials qualification of the special processes and tools neces- of high permeability will be characterized for verifi- sary for the assembly of photovoltaic generators on cation of the quality of national and imported mag- structures for aerospace applications. Phase 1 begins netic material and of the possibility of reversing the with the collection of data on technical norms and the harmful effects of the cutting process by heat treat- applicable generic requirements up until the final con- ments. It will be possible to construct a data base of ception of the testing and qualification level. In phase the various magnetic materials. One of the innovati- 2, the objective is to develop and qualify the manufac- ve proposals is in the implementation of a micropro- turing processes, devices, and special tools in eight cessed re-excitement mesh which will permit the use sub-phases, namely: 1) Implement and apply to the of lower cost magnetic materials, making its com- following sub-phases the Product Guarantee Plan mercialization on the Brazilian market easier. The worked out in Phase 1; 2) Manufacture of the Special conclusions of this study will lead to the gradual de- Devices and Tools designed in Phase 1; 3) Acquisition velopment of more accurate current transducers of Complementary Materials, Components and The principal motivation, in the medium term, is to Equipment; 4) Assembly and adaptation of the Special develop small, low cost current alligator clips which Devices and Tools; 5) Development of Manufacturing can be attached to an oscilloscope. New configura- Processes by means of the manufacture of develop- tions to increase the sensitivity of the transducers ment test samples; 6) Manufacture of Qualification and extend their frequency response will be tested. Test Samples; 7) Qualification tests; 8) Final Project The transducers’ magnetic circuit will be optimized Documentation. The envisaged results are technologi- by means of simulation using the Finite Element cal capability and qualified manufacturing processes Method, to optimize both the linearity and the sen- to meet the growing demand for energy generation sitivity of the transducer. Magnetic circuits with equipment for the aerospace sector. Some direct bene- more than one non-magnetic spacer will also be stu- fits are the replacement of imports and the stemming died, aiming for the construction of bipartite cur- of the outflow of foreign currency; local job creation; rent transducers. A study will also be made of me- the possibility of exporting products and services with thods for the linearization, calibration and high technological content and added value; and, in compensation of the thermic variations of the trans- addition, the possibility of applying this technology in ducers with the aim of implementing algorithms in the development of other products.

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10th BIDDING INSTRUCTIONS Approved value: Phase 1: R$ 62,000 Phase 2: R$ 270,820 Applied Molecular 192 Biology to the Rational The hermetic encapsulation of optoelectronic Management of Ostriches components requires the use of metal solders in their interiors. In these encapsulations laser diodes Coordinator: and photo-detectors are used which have to be cou- Adriana Medaglia pled to optical fiber which is composed of melted quartz. In order for the fibers to be attached by Company: means of the solder process it is necessary that they DNA Consult Genética e Biotecnologia Ltda. have metal deposited on their surface. The technique Approved value: of vacuum metallization is the most commonly Phase 1: R$ 64,648 used, but its cost is high. This project aims to de- Phase 2: R$ 297,962 monstrate the viability of the deposition of metallic layers on optical fibers by chemical process at low The ostrich industry is growing at a very fast pace cost. The process to be used will be an adaptation of in Brazil and in other countries, representing a world a technique already mastered for the metallization of market in the order of millions of dollars. Brazil is vitreous ceramic substrates. This study involves sta- considered internationally the country with the grea- ges of superficial modification of the fiber (melted test potential for rearing this bird. Molecular biology silica) through the use of watery buffer solutions. techniques allow forms of rational management, Into the structure modified in this way will be in- providing an increase in the profitability in breeding crusted small nuclei of palladium metal which will for slaughter and reproduction, as well as possibilities be used as a support for the chemical reduction of for the early commercialization of animals. This pro- the nickel which it is intended to deposit. Following posal aims to develop and implement technology for this, on the nickel, an electrolytic thickening of me- the carrying out of genetic analysis in ostriches, from tals will be carried out. These metals will enable the the collection of material in the field to the formula- soldability of optical fiber in optoelectronic encap- tion of reliable products and services for the commu- sulations. Having demonstrated the viability of the nity of breeders. Productivity can be improved project in this first phase, the company embarked on through the genetic selection of matrixes. The brie- the second stage of the work, which consists of pre- fest description of genetic relationships diminishes paring a chemical laboratory for the handling of the the possibility of loss of genetic variability and even raw materials needed for this technology. allows for the certification of the origin of the chicks. The sexing of very young animals, today carried out by cloacal examination, is difficult to interpret, gene- Mass Breeding and rates errors and even causes stress, infections and le- 194 Commercialization of Trichogramma sions which prevent the commercialization of the spp and Cotgesia flavipes for bird. The objective of this study is to create improve- the Control of Agricultural Pests ments in the commercialization of very young chicks reliably sexed, as well as improving productivity, Coordinator: using matrixes that are not related. Alexandre de Sene Pinto/José Roberto Postali Parra Development of the Company: 193 Technology for CP2 Ltda-ME (Bug) the Metallization of Optical Approved value: Fibers by Chemical Process Phase 1: R$ 72,876 Phase 2: R$ 279,725 Coordinator: Alexander Flacker The aim of this project is to make available to Company: the user good quality insects, since the lack of this Optolink Indústrias e Comércio Ltda. requirement represents the greatest obstacle to the

Translating Research into Business • 157 popularization of biological control in Brazil. No- in the northern and southern hemispheres. It was wadays, there is enormous interest in the use of this introduced into Brazil in the 1950s and today it is to alternative, but insects are not always available for be found almost throughout the country, in com- purchase and, when they are, the biological speci- mercial farms as well as reservoirs and artificial la- mens are not always of the desired quality. The in- kes. Among the varieties of tilapia used in piscicultu- sects will be produced using conventional techni- re, the Nile tilapia (Oreochromis niloticus) has been ques which will be fine-tuned, adapting them to the the most widely bred. Red tilapia is a mutational va- Brazilian reality, especially in the acquisition of riant which was discovered in the 1960s, in Thailand. components of artificial diets for breeding, lowering Among the tilapia species in which the mutation to- the manpower costs and monitoring biological cha- wards the color red was observed, the O. niloticus is racteristics through the generations to ensure the outstanding. The present project aims to develop an quality of the insect produced as well as its perfor- interspecies hybrid of tilapia which combines the su- mance in field conditions. The project intends to perior zootechnical qualities of the chilatrada va- use Cotesia flavipes (Cameron, 1891) in cane sugar, riety of O. niloticus with the red coloration of the O. a larval parasitoid for the control of Diatraea sac- niloticus Red-Stirling variety so prized by the mar- charalis (Fabr., 1794), traditionally used in Brazil, ket. The results presented in phase 1 of the present and Trichogramma spp., an egg parasitoid which can project underlined the potential of the Red-Stirling be used to control this pest in areas where the egg- variety in terms of its zootechnical performance in predation is low or in areas where the climatic con- field conditions, as well as its low index of endo- ditions did not permit the adaptation of the braco- gamy, an important factor for the implementation of nidae mentioned. In this case, Trichogramma galloi practices of genetic improvement through selection. will be used, with other species of Trichogramma Thus, with the establishment of phase 2 of the pre- (especially T. pretiosum) being suited to commercia- sent project, the goal will be to produce beginning in lization for the control of lepidopterans in tomato the second year 3,410,000 young fish per year. Inves- (vine, staked and in greenhouses), cotton plants, tment in this phase will enable the setting up of an maize, etc., since the production of these natural intensive and continuous system for the production enemies is considerably advanced in our conditions. of young fish that will be monitored through the analysis of genetic markers to assess their quality.

Genetic and Zootechnical 195 Evaluation of two Varieties of Nile Advanced System for the Production Tilapia (O. niloticus var. Red-Stirling 196 of Electricity with High Efficiency, and O. niloticus var. chilatrada) for Low Cost and Non Pollutant the Establishment of Program for the Mass Production Coordinator: of a Hybrid of Red Tilapia Antonio César Ferreira Company: Coordinator: Unitech Ltda. Alexandre Wagner Silva Hilsdorf Approved value: Company: Phase 1: R$ 31,570 / US$ 8,600 Agropecuária Saint Peter S/C Ltda. Phase 2: R$ 16,250 Approved value: Phase 1: R$ 30,804 / US$ 2,000 The project aims to develop a system for the Phase 2: R$ 86,323.60 production of electricity, using fuel cells integrated to a hydrogen production system. Two sources of The production of fish in captivity has taken on hydrogen will be researched: solar energy (via the an important role in the total amount of fish availa- electrolysis of water) and ethanol reform. Studies of ble for human food, the production of fishmeal and this first phase will be undertaken to ascertain the oil. Changes in eating habits, that is, the search for technological and economic viability of the two foods of animal origin with low levels of cholesterol sources of hydrogen. In the case of water electroly- and high protein value, has placed fish on the daily sis, solar energy will be used as the primary source menu of many populations. Tilapia is a fish of Afri- of energy. Despite the electrolysis of water being can origin, however, it is farmed in various countries commercially used, its use in the production of elec-

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trical energy is costly when compared to traditional enables a cheap and economically viable solution for means of generating electricity. In order to reduce this case, especially for small and medium enterpri- the cost of hydrogen, experiments will be carried ses. The second module concerns the tracking of ve- out to produce it by means of the technology of ion hicles via global positioning satellites (GPS) and the conducting polymer type electrolyzer. Electrolysis making available of the positioning on the internet. in ion conducting polymers has shown an energy The tracking, offered by businesses for many years, reduction of up to 20 per cent. The price of the ki- aims especially at security. Nevertheless, by placing lowatt/hour (kWh) with the use of the solar ener- the information concerning the position of each ve- gy/electrolyzer/fuel cells system could be US$ 0.11. hicle on the internet, it is possible to achieve cost re- At this cost, this form of producing electrical ener- ductions, an increase in flexibility and portability gy could have enormous technological and econo- and, more importantly, it can also make the infor- mic potential. On the other hand, a cubic meter of mation accessible to the sender of the goods, ena- ethanol can produce up to 5 cubic meters of hydro- bling better logistical planning. The first phase of the gen through the reformation reaction. In this way, project demonstrated that the technology available the kWh cost could drop to US$ 0.049. This value today now permits the development of such systems makes the use of the ethanol reformation/fuel cell in an integrated form and with a relatively low final system to produce electricity extremely attractive. cost of acquisition and maintenance. Also in the first phase of the project, new types of catalyzer for the reformation of ethanol based on Palladium, Platinum and Cerium will be resear- Electronic Anticorrosive ched. These catalyzers have been used in the refor- 198 OX-FREE Protection mation of natural gas, methanol and gasoline. Coordinator: Ary Biazotto Corte Junior Management of Company: Road Parcel and Freight 197 Bhar Indústria e Comércio Ltda. Services via Internet Approved value: Coordinator: Phase 2: R$ 249,242 Antonio Fabrizio Lima Passari The present research project aims to characterize Company: the theoretical methodology for anti-corrosive elec- BR Express Ltda.-ME tronic protection, verifying results obtained from Approved value: the field experiments to date. The work is divided Phase 1: R$ 24,045 into nine stages. Stage 1: implementation of electri- Phase 2: R$ 149,980 cal and electro-chemical experiments in laboratory; stage 2: the taking of measurements in the field and The project aims to develop software tools to im- in the laboratory; stage 3: implementation of im- prove logistics operations, using the communica- mersion trials in synthetic sea water, in synthetic se- tions infrastructure of the internet allied to the trac- wer water; in a diluted solution of sulfuric acid, in a king of packages and the positioning of vehicles via diluted solution of hydrochloric acid, in a diluted so- satellite. The proposal arises from the needs demons- lution of sodium hydroxide and in water from the trated during the operation of the system of freight public supply; stage 4: implementation of soil corro- contracts and the optimization of the transportation sion tests; stage 5: implementation of accelerated of cargoes developed by the company. The project is corrosion tests; stage 6: implementation of field tests divided into two distinct but complementary modu- to verify the protective efficiency in marine atmos- les. The first relates to the tracking of requests for phere, urban atmosphere and industrial atmosphe- collection, transport and delivery of merchandize. re; stage 7: evaluation of the body of evidence deri- Information on the status of each order entrusted to ved from the tests in stages 3 to 6; stage 8: simulation a transport company – or even supplier/partner – is and analysis of the types of corrosive action in the of great importance for the logistical planning and body of evidence; stage 9: analysis of the results and programming of its activity. The internet has conso- establishment of criteria for the correct use and di- lidated itself as a means of communication which mensioning of Ox-Free.

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Stoq: A Flexible System Approved value: 199 for the Management Phase 1: R$ 75,000 of Commercial Companies The present proposal aims to research and deve- Coordinator: lop experiments to test, in a judicious manner, exis- Christian Robottom Reis ting equipment on the market (commercial stan- dard) in terms of resistance of materials and Company: adjustments needed for them to be used in interacti- Async Serviços de Informática Ltda. ve experiments. The intention is to adapt these items Approved value: of equipment, with a view to better operating condi- Phase 1: R$ 21,957 / US$ 1,200 tions, principally in terms of yield, in addition, to in- Phase 2: R$ 80,740 novate their systems-standard regulation, adjusting them to new ends. The project also aims to establish The Stoq project involves the creation of a set of a systematic and scientific criterion for the develop- applications for the management of medium and ment and construction of new experiments. For this small enterprises, built with the use of tools based on purpose, it is necessary to undertake a broad techni- free software. The set of requirements expected from cal and bibliographical research, contract specialist the project includes: ease of customization – Stoq has advice in the universities and centers of research and to be easily configurable to meet the needs of the dif- seek partnerships with businesses interested in pro- ferent types of business; internationalization, given moting their products and associating their name that the software needs to be easy to translate into with a scientifically interesting experiment. In this other languages; integration with the community of sense, we will seek a technological refinement to ma- developers, to which it must be accessible. In addi- nufacture new experiments, that will not only be very tion to this, the project must generate the offer of ser- attractive, but also robust, practical, low in consump- vices to complement the software, among which ins- tion and require little maintenance. Such an objecti- tallation, maintenance, training, customization and ve requires effort in the sense of refining projects and support. The proposal is to turn Stoq into a manage- developing several prototypes. In this way, the endea- ment platform to be widely used by national busines- vor is to improve the quality of experiments presen- ses, offering facilities for integration into the produc- ted in the company to attract a greater public and to tive chain, distribution and customer support. The increase sales to other interactive museums. project now has an extensive knowledge base and has partnerships with commercial enterprises as it sour- ce of resource. In the second phase of the project, it is Development of planned to develop the applications as well as the 201 Processes for Syntheses platform, on the basis of the process established in of Desferrioxamine phase 1, and to work to make accessible and promo- te the use of the applications and platforms among Coordinator: institutions which can support and use the project’s Durval Marcos Vieira products. A set of software components has been es- tablished which will be fine-tuned to meet the stiff Company: requirements of the application. This platform inclu- Erythro Assessoria Química S/C Ltda. des Python, ZODB, and GTK+ packages and Async, Approved value: Kiwi and IndexedCatalog products. Phase 2: R$ 299,646

At present desferrioxamine is the only pharma- Interactive Experiments ceutical of safe use in the reduction of the build up 200 for Scientific and of iron in the organism. Although it is no longer Technological Education protected by patents, its manufacture is carried out practically by a single laboratory and its commercia- Coordinator: lization has a high price throughout the world. The Dalton Gomes de Mello present project aims to develop an efficient process Company: for the synthesis of desferrioxamine, which is requi- Tecnorama Brinquedos Educativos Ltda. red in order to enable its local production.

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Complete Encapsulation Company: of Discardable Blood Brats Indústria e Comércio Ltda. 202 Pressure Transducers Approved value: Phase 1: R$ 61,040 Coordinator: Phase 2: R$ 228,000 Edgar Charry Rodriguez Company: Sinterized metal filters are produced using pow- Torr Microsistemas Integrados der metallurgy techniques and the most commonly de Pressão Ind. e Com. Ltda. used is uniaxial compactation in matrix by hydrau- lic or mechanical presses. Depending on the type of Approved value: application, a variety of materials may be used, Phase 2: R$ 155,100 among which bronze, stainless steel, inconel, hastel- loy, monel, aluminum and titanium. In Brazil, the The microelectronic technologies currently esta- bronze filter market is well developed, with a few blished, appear now as a strategic pillar which made modest-sized companies active. As for other mate- possible an industrial revolution and, specifically rials, there exists a large market to be exploited, es- now, permit a high competency in sensor technology. pecially of stainless steel filters 316L and 304L, which Thus, semiconductor businesses have entered the are the subject of this proposal. There exists demand sensor market with a logical expansion of their acti- for various applications, especially in the industry of vities in integrated circuits, because they already have gases with flame-cutter filters, dosers, attenuators, most of the equipment necessary for their manufac- tubes and porous plates for the petrochemical in- ture and the appropriate marketing channels. Silicon dustry and cartridges with or without seams for the pressure sensors represent today the largest percenta- alcohol industry, all in stainless steel. Some cases of ge in the world market of products generated by special filters in inconel, monel and titanium for the MEMS (Micro Electro Mechanical System) techno- chemical and nuclear industries were also identified. logy. This technology has over the last 20 years, dras- In the majority of these applications, all with high tically altered the markets for sensors, activators, ins- added value, components such as replacement parts trumentation and control. The present research aims are imported and the national industry has enor- to develop a complete process for the manufacture of mous difficulty discovering who makes these special discardable silicon blood pressure transducers for parts to measure. The main objective of this research biomedic use. This concerns a product without na- is the determination of the parameters for compac- tional parallel, which will shift the technological de- tation and sinterization necessary for the elabora- velopment of this area into a new gear. Torr Microsis- tion of porous materials with the performance with temas is the fruit of 15 years research carried out in appropriate characteristics for the applications of li- technological centers located in the State of São Pau- quid-liquid and solid separation, in the mechanical, lo (the Polytechnic School of the University of São chemical and food industries. Phase 1 of this project Paulo, EPUSP, the Institute for Technological Re- verified the viability of the production of porous search, IPT, and the Heart Institute, InCor). The ob- metal parts (filters) with high technical and com- jective is to develop, manufacture and commercialize mercial performance. Phase 2 seeks to make viable these devices to meet the demand from the health the installation of a manufacturing unit to produce sector. The discardable blood pressure transducer parts which will replace the importation of a part of consists of a silicon microchip, an internal capsule the porous elements consumed in Brazil. and protective gel, and an external capsule with inter- connections and electrical and fluid connectors. The technical specifications of this transducer should Evaluation and Optimization of the conform to all the international norms. 204 Metallurgical Properties of Aluminum Billets for Extrusion Produced from Recycling of Scrap Metal Production of Porous Parts in High 203 Coordinator: Performance Alloys Gisele Szilágyi Coordinator: Company: Francisco Ambrózio Filho Metalex Ltda.

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Approved value: Company: Phase 1: R$ 73,830 AFLORD - Associação dos Floricultores da Região da Via Dutra The quality and productivity of the extrusion pro- Approved value: cess of aluminum alloys depends heavily on the raw Phase 1: R$ 25,280 material used, that’s to say, on the billets obtained Phase 2: R$ 121,365 through the process of semi-continuous Direct Chill (DC) casting. Although the Brazilian market has a few The are serious problems which affect the com- suppliers of good quality DC billets, their costs of mercial production of the wild orchid Oncidium fle- production are very high. This being so, companies xuosum. The first is the intercrop between the months which produce extrudes, the vast majority of which of January and April. The company promoted pro- are not large businesses, end up relying on small sup- duction during this period by the use of methods of pliers or on the internal production of ingots (not DC photoperiod control and pruning. Precisely because it billets), which leads to low quality of the billets and, is a wild orchid recently adapted to commercial culti- consequently, to lower productivity and quality in vation, the Oncidium flexuosum displays great varia- their products. Thus, there is a lack in the production bility, especially in the flowering period. One of the of good quality and low cost billets in the Brazilian ex- important pieces of research undertaken in the first trusion market. In this scenario, the production of phase of the project dealt with the selection of plants DC billets derived from the recycling of scrap metal is and the reconstitution of different populations which an excellent alternative compared to the use of pri- possess a well-defined flowering period, from April to mary aluminum, typically used by the large national August. The work was carried out at a rather slow producers of billets. The recycling of scrap aluminum pace since it demanded a wide collection of materials also offers a substantial reduction in the consumption from a variety of sources, production trials with repe- of electrical energy. However, the intense use of scrap tition and, above all, personnel skilled in reproduc- in the production of billets could bring about pro- tion by means of meristematic cultures in the labora- blems of quality in the DC billets. The present project tory with suitable conditions and equipment. Based focuses precisely on this aspect: the replacement of on data obtained from trials in phase 1, for phase 2 a primary aluminum with recycled aluminum in the project was designed to select plants from the phase 1 smelting load, controlling the process, striving for a based on crossbreeding between 60 plants selected quality of billet comparable to the conventional billets from different sources. 300 crosses will be carried out obtained by using primary aluminum. The aim is to between them and it is intended to obtain 200 plants characterize the metallurgical quality of billets produ- from each one, making a total of 60 thousand pro- ced by a recently established company which uses an geny. The intention is to analyze the DNA of the innovative process based on recycled scrap, having as plants selected and verify the possibilities of determi- main focus the effects of the use of scrap in the qua- ning the most favorable crosses to obtain the desire lity of the DC billets produced. To this end, compari- genotypes. The selected progeny will be propagated in sons will be carried out between samples of DC billets vitro and will constitute the commercial cultivars that produced using recycled scrap and samples of DC bil- will be distributed to producers. lets smelted conventionally, by means of micro and macro structural analyses, as well as heat malleability. It is intended to produce good extrudability in those billets through the study and consequent control of Production of Purified Plasmidial the smelting process, and through the optimization of 206 DNA and Recombinant Proteins, the thermal treatment of homogenization. on a Large Scale, for use in Vaccines and Diagnostics

Study of the Means of Coordinator: 205 Controlling the Flowering José Maciel Rodrigues Junior Time of Oncidium flexuosum Company: sims. and Selection of Nanocore Biotecnologia Ltda. Plants for the Reconstitution (ex-Life Sciences Ltda.) of Uniform Populations Approved value: Coordinator: Phase 1: R$ 23,525 / US$ 21,000 Hiroshi Ikuta Phase 2: R$ 300,060

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The project aims to develop the production of Company: plasmidial DNA and recombinant proteins to meet Eonic Brasil Ltda. the demand of researchers and also to open perspec- Approved value: tives for a new profile for the company. The project Phase 2: R$ 48,725 introduces significant technological innovation, gi- ven that the national market does not have access to This project aims to develop a graphical tool for such a product. In the first phase of development of the generation of source code for parallel real-time the project studies were undertaken of the purifica- systems, executed with the support of the Virtuoso tion process of plasmidial DNA in the scale of 1 parallel kernel, developed by Eonic Systems. Virtuoso gram, meeting the criteria of regulatory require- is built with a layer on top of C programming lan- ments, which permitted the start of the planned cli- guage, giving it functionalities similar to a parallel nical studies, presently in progress, applied to the programming language. To offer support to the ker- treatment of epidermoid tumors in humans and bo- nel a set of tools are required which assist in the de- vine tuberculosis. From the information available, it velopment of parallel applications, debugging of er- is the first time that a company has mastered the rors and analysis of the requirements of real time. technology of purification of plasmidial DNA on a The aim of Visual-RT is to help in the generation of large scale in Brazil. The competitive differential is source code for programs executed in the parallel immense and the costs of production are 15 to 20 ti- machine. In Visual-RT, applications are represented mes lower. Two commercial proposals are presently in a graphic model, which will be used to integrate being analyzed, in order to subsidize the develop- the other tools which make up the visual environ- ment and clinical study of two DNA vaccines in de- ment. The main component of this model will be a velopment with national researchers. Phase 1 of the graphic, where the nodes will denote the data struc- project aimed to obtain the large scale production of tures of the parallel program and the peaks will re- DNA and its results proved to be totally viable and present the communication and synchronization they are in harmony with the broader aims of the operations related to these structures. The informa- project. Namely, the production of a vaccine against tion from the graphical models could be comple- tuberculosis, which was recently patented by FAPESP mented with text descriptions, that’s to say, stretches and the University of São Paulo, USP, and optimized of code written by the user. On the basis of the gra- by researchers from USP and the Federal University phical and textual information, the tool will automa- of Minas Gerais, UFMG. The latter based itself on the tically generate the application source code. Visual- incorporation of plasmidial DNA in biodegradable RT will also help the programmer to maintain polymeric systems. In phase 2 of the project the aim continuity in the development of projects which use is to obtain a stage of fermentation now on a semi- methodologies for the most commonly used real- industrial scale (100 liters) and the production of mi- time systems, facilitating the transition from the ini- cro-structured systems on a scale of 100 grams to 1 tial phases, that is, analysis and design, to the imple- kilogram in order to enable clinical studies. The focus mentation phase. To help the programmer execute this of this stage is the optimization of the production of transition, the tool will permit the development of plasmidial DNA and the application to other types of prototypes of the parallel program, which will gra- DNA in addition to the model worked on till then, dually be improved until the final product is obtained. which equates to the protein exposed to 65 KDa (hsp65) thermal shock and the development of the large scale production of non-living systems of trans- Development of Computational genic infection based in biodegradable polymers and 208 Tools for the Teaching and lipids on a pilot scale of cationic nano and micro- Learning of CNC Usage Processes spheres and deprived of charges. Coordinator: Marco Stipkovic Filho Visual Environment for Company: the Development of Parallel 207 Adiante Informática Ltda. Real-Time Programs (Visual_RT) Approved value: Coordinator: Phase 1: R$ 11,520 José Roberto Pinto Ribeiro Phase 2: R$ 59,380 / US$ 15,039

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This research project aims to develop educatio- the literature studied. The components of the poly- nal software to promote and facilitate the teaching of mer/ceramic system were selected on the basis of usage processes with the use of CNC technology in properties and compatibility/stability of the mixture. institutions of technical and higher level. The main However, other polymers and mineral loads will be justification is in the fact that there is a lack of com- tested to improve the performance and decrease putational teaching resources of national origin (na- costs. These products should be totally recyclable or tive in Portuguese language) – low in cost and of possible to source in the environment without any compatible performance with the installed compu- great worries or controls. For the first time, the use of ter base in schools –, which are capable of promoting reticulation by ionizing radiation was proposed as a the teaching and learning of usage processes. CNC basic tool for this class of product. The application of technology was chosen as facilitator of this process, radiation induced polymerization to the system given that it offers a flexible, programmed form, ca- composed of methyl methacrylate monomer base, pable of being implemented via software. In phase 1 mixed with other components will allow for fine con- of the project the following activities were promo- trol of the reaction, since radiation polymerization ted: analysis of the project viability based on market enables a greater control of the process, as the energy conditions (customers, competitors and suppliers) can be delivered directly to the reactive mass without and technology (software, algorithm, performance); heat transmission problems. In the application of analysis of the computational tools of development this technique bubbles and products of thermal de- and support, which culminated in the generation of gradation are absent, since radiation dispenses with functional prototypes of the modules of turning and the use of radicalar initiators. The absence of residual machining capable of interpreting and simulating monomers is also confirmed, since radiation allows CNC programs in ISO language. In the second pha- for higher conversion than in any other process, eli- se, the proposal is to elaborate the necessary algo- minating the presence of monomers which can post- rithms, among which the topics of tool selection and polymerize. In addition to this, in the case of irradia- process conditions; to fine tune the man-machine tion by accelerated electrons, curing is immediate. interfaces and codify events; to generate support material; to carry out preliminary tests of programs under conditions of use; and to promote certifica- Development of an Operational tion and production. 210 Prototype for an Alternative Rotating Engine Known as Tetracycle

Development of Compounds Coordinator: 209 from Ceramic Waste as Olympio Sambatti Replacement for Granite, Company: Wood, and other Quality Facings S.H. Empreendimentos e Participações Ltda. Coordinator: Approved value: Paulo Carlos Galin Phase 2: R$ 174,520 Company: This involves a project which went through a PERC - Engenharia Ltda. long initial phase of development as proof of con- Approved value: cept, in which two engineering models were studied Phase 1: R$ 68,934 which demonstrated excellent qualitative results. Phase 2: R$ 198,000 The engine is a technological innovation, presenting a low weight/power relationship associated with a The proposal contemplated is innovative with re- high torque. It possesses four combustion chambers gard to the components of the compound, that is to in the form of cylindrical sectors delimited by four say, the present project aims to develop a hybrid juxtaposed and rotating pistons which execute a non compound based on PMMA and inorganic materials uniform movement between them, permitting ad- on the national market, such as: assorted industrial mission, compression and escape. Each rotation of waste, aluminum, granite dust, marble dust, glass the set of 4 chambers/4 pistons, permits a sequence dust, among others, which may confer interesting of four explosions. The present phase of the project properties on the polymer such as those observed in proposes to develop and manufacture a working

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prototype in order to obtain quantitative results which helps in the control, storing, organization and with a view to its qualification, industrialization and processing of data from the entire production pro- commercialization. The work will be divided in four cess of ostrich breeding. stages: design, manufacture and assembly, tests in bench trials and verification of performance. Manufacture of 212 Self-reducing Development of Integrated Manganese Pellets 211 Management System for Ostrich Breeding ventures Coordinator: Ricardo Silveira Braga Coordinator: Company: Ricardo Firetti Agronutri Indústria e Comércio Ltda. Company: Approved value: Brasil Ostrich - Coml. Imp. e Exp. Ltda. Phase 2: R$ 190,000 Approved value: Phase 1: R$ 60,660 The work involves the manufacture, characteriza- Phase 2: R$ 117,879 / US$ 156,964.20 tion and reduction of self-reducing pellets of manga- nese ore, using an alternative binder which permits Brazil is considered in the world ostrich-bree- the cure of the pellet in cold state. Initially the binder ding community as one of the countries with the to be used is an industrial residue with no technologi- greatest growth potential in this activity. The vigo- cal application, which constitutes an environmental rous growth of flocks in the country has been noti- problem for its producer. This residue is the dust from ceable over the last few years. The first imports oc- the dedusting system of electric reduction kilns which curred in 1995 and the market has grown at rates of contains compounds which, on reacting in the pre- around 30 per cent per year. However, for Brazilian sence of water, permit the formation of solid hydrated ostrich-breeding to achieve a competitive space in compounds which serve as a binding element bet- the market, certain actions have to be set in motion. ween the crystals of ore and reducer, creating a pellet Amongst them, effective tracking programs, the ge- resistant to cold and hot management. The intention netic improvement of flocks and improved manage- now is to synthesize the binder, so as to offer the same ment of the businesses which comprise this activity; binding features as the dust from the dedusting. This it would be of considerable value to create a mecha- artificial production will be based on identification of nism for centralizing technical and economic infor- the mechanisms which cause the cold binding. In this mation, thus enabling an efficient business manage- phase the behavior of the pellet will be studied, with ment process, imposing traceability on the products variations in the proportions of CaO and Si02 and and making available data on the origin of the ani- K2O of the same (tricalcic, pozzolanic and crystallized mals. This is the basic proposal of the present project bonds). These variations will be obtained through the which aims to develop a piece of software in part- appropriate mixture of binder, Portland cement, alu- nerships with businesses specialized in the breeding minum cement, microsilica and activated ash, among of ostriches and in computer science, capable of others. 50 ton lots will be produced, reduced in elec- bringing together indispensable information for the tric kilns and rotating kilns for the production of management of business and the implantation of manganese monoxide and high-carbon ferro manga- programs of genetic improvement geared princi- nese. With this, an analytical study of the reduction pally to the productive segment. Phase 1 of the pro- mechanism will be carried out which, comparing ject regards the technical viability of the proposed with previous results, could considerably alter the un- ideas via the gathering of information pertinent to derstanding of the process. These results will permit the system, to the definition of its scope and logical the complete modification of the manufacturing pro- functions and the analysis of the alternatives of sup- cesses of manganese and ferrous monoxide, manga- port software in its elaboration. Phase 2 proposes to nese-based alloys, with a conservatively estimated re- develop a system of computerized management duction in cost of manufacture of up to 35 per cent.

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Production and Development of Commercialization of Instrument for Measuring 213 Equipment for the 214 Thermic Diffusivity of Electro-Chemical Treatment Materials by the of Watery Industrial Energy Pulse Method Effluents Containing Organic Pollutants Coordinator: Thomaz Augusto Guisard Restivo Coordinator: Company: Rosângela Rodrigues Leme Pelegrino METALTECH Sorocaba Company: Equipamentos e Serviços Ltda. Tech Filter Indústria e Comércio Ltda. Approved value: Approved value: Phase 1: R$ 35,566 Phase 1: R$ 50,746 Phase 2: R$ 167,215 Phase 2: R$ 281,972 The project aims to develop an instrument for The aim is to transform the electro-chemical oxi- the measurement and evaluation of the thermal dif- dation process of organic pollutants in an industrial fusivity and conductivity of materials with a view to process which does not require the addition of any its commercial exploitation. The technique to be chemical reagent, does not generate sub-products employed uses a pulse of energy, in this case a visi- that require new inertization treatments, have a fas- ble light (flash) of brief duration, striking the face of ter kinesis than biological treatments and occupy a a discoid sample, established at a certain temperatu- smaller physical space. It is intended to design, build re in the range of 20-1200oC. A temperature sensor and optimize electro-chemical reactors for the com- records the progression of this on the sample’s op- pany’s use and to be commercialized. For this purpo- posite face in terms of time (thermogram). The data se, designs and tests will be undertaken aiming to an- is collected and transferred to a piece of software ticipate the occurrence of problems arising from the which develops the routine for the determination of transposition onto an industrial scale, with the pro- thermic diffusivity using the thermic quadrupole posal of possible solutions. The work also includes method. In the first phase of the project a prototy- the design, detailed dimensioning and selection of pe was set up for the ambient temperature with an materials for the reactor and its components, hydrau- option up to 60°C. The results were compared for lic installations, electrical installations and power some materials, using the existing laser pulse instru- supply and measuring and control instrumentation. ment in the Materials Laboratory in the Navy Tech- A test module will be set up for experimental opera- nology Center in São Paulo (LABMAT -CTMSP). tion to support the project in terms of the optimiza- Phase 2 of the project involves the consolidation of tion of the distribution of electrical current in the the instrument as a commercial product, including anode, the optimization of the distribution of fluid the physical set-up of the components, conception velocities, the choice of a suitable material for the and construction of the control panel, automatic turbulence promoter, and the processing of samples acquisition system and adaptation of the analytical previously characterized for the evaluation of the software. A heating oven will be added to the system reactor’s performance. The basic proposal of phase 2 which will make it possible to analyze thermic dif- of the project centers on the construction of a mobi- fusivity in different isotherms, in addition to esta- le effluent treatment station with a 60 m2 area of ano- blishing the maximum temperature at which the des for electrochemical treatment attached to ten instrument can be used. An infrared sensor will be photo-electrochemical reactors as complementary evaluated along with thermopair sensors. Opera- treatment. The mobile station will be placed into ting, control and analysis software will be developed operation, for periods of two to three months in aiming to automate the test. Other applications of companies that have participated in the project up to the system, with the simultaneous determination of the present time, which opened their effluent treat- thermic capacity and evaluation of conductivity are ment stations so that the analytical monitoring of also envisaged. their waste could be carried out.

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Robotized System for The project involves the development of a per- 215 Inspection of Tubing manent adhesive glue resistant to bad weather. Based on previous experience the base used is polyolefin Coordinator: and polyisobutilene elastomers as these are almost Walter de Britto Vidal Filho totally saturated and offer high resistance to oxida- tion in atmospheric conditions. The elastomers Company: mentioned must be mixed with synthetic hydrocar- MWA Comércio e Serviços Ltda-ME bon resins and plastifying oils. The basic composi- Approved value: tions (elastomer + tackfier) in a sealed mixer (Bam- Phase 1: R$ 46,276 bury) to lower the fusion point of the elastomers. The final compositions of the formulations will be The project involves the presentation of a ventu- done in heated open boiler. The adhesives obtained re in the area of working mobile robots to develop a will be analyzed for viscosity at temperatures of robot for inspecting ducts from their interiors. In 1200ºC and 1500ºC, using Brookfield viscosimeter, the first phase of the work a prototype will be deve- and softening point, using equipment appropriate loped along with a technical verification of its viabi- for the test. The melted adhesives will be placed on lity. The prototype will be based on a platform for polystyrene sheets with the appropriate format, movement in straight or curved, horizontal or slo- using the Hot Melt applicator. After cooling, they ping tubing, with diameters varying from 250 to 500 will be analyzed for initial adhesion with an Emic millimeters; it will have a control architecture to dynamometer and force of static shearing, using a which an operator issues orders in response to ima- weight of 1 kilogram per square inch of surface. The ges captured by high resolution cameras positioned result will be the best formulation for the produc- at both ends of the vehicle. The video cameras will tion of a pilot batch which will be evaluated and possess an actioning mechanism. To this first pro- aged – both real time and accelerated – for three totype a piece of ultra-sound equipment will be at- months in a forced air circulation oven. On the basis tached for measuring the thickness of the duct wall. of good results obtained in the first phase of the pro- Some market requirements to be addressed by the ject, in the second it is intended to develop and pro- company by means of the project currently being duce glue traps for mice, cockroaches and flies. presented will be: the undertaking of inspections wi- thout the need for dismantling or moving – which reduces the cost and the time spent on the job; the Optimization of Performance inspection of buried tubing; the inspection of tubing 217 of Heat-reflecting Curtain, where “instrumented PIG” type of equipment is Aiming for Reduction of Energy unable to operate; the localized inspection of tubing, Consumed in Thermal Conditioning valves and/or duct accessories. The main users of the product/services to be catered for by MWA should Coordinator: be businesses from the oil and gas sectors, chemical Antonio Sergio Assunção Tavares and petrochemical industries and petrol refineries. Company: Vacuoflex Tecnologias Refletivas Ltda. 11th BIDDING INSTRUCTIONS (ex-Quiminox Ind. e Comércio Ltda.) Approved value: Phase 1: R$ 74,900 Development of High 216 Performance Adhesive The aim of this project is to develop a heat-reflec- For Use in Urban Traps ting curtain capable of providing a considerable re- duction in the consumption of energy in the thermal Coordinator: conditioning of the building, or an increase in the Antonio Ademir de Andrade thermal comfort of naturally climatized rooms. It is known that the glassed areas of a building, owing to Company: the poor thermal insulation they offer – against heat Colly Química Indústria e Comércio Ltda - ME conduction or solar radiation – are responsible for a Approved value: large part of the thermal exchanges which occur bet- Phase 1: R$ 57,212 ween the building and the external environment. In Phase 2: R$ 253,235 warm and sunny climates such as Brazil, in buildings

Translating Research into Business • 167 with several floors, the heat that enters via the glassed plify the systems for conditioning signals and reduce areas accounts for the most important part of the the cabling required, contributing greatly to the ove- heating. This being so, the idea to use a curtain with rall cost reduction. These sensors, since they have the a high degree of thermic insulation seems an obvious capacity for the local storage of data and since they solution to improve the thermal comfort of a room are interconnected in an expandable system on a fi- and ultimately increase the effectiveness of the condi- ber optic network, which offers great immunity to tioning equipment. The use of reflective insulators electromagnetic noise, represent a flexible and effi- allows for the creation of light, cheap curtains, that cient solution. Since such devices carry microproces- are thin and have a high degree of thermal insulation sors, they offer local processing capacity, enabling the in conduction and radiation. The quantification of volume of information exchanged between the va- the thermal performance of this reflective curtain rious components of the diagnostic system to be will permit the cost/benefit calculation for the pro- enormously reduced, among other advantages. The duct in various situations, making a solid base for its introduction of such intelligent sensors to the predic- development on an industrial scale possible. There- tive diagnostic system should permit a significant re- fore, two test installations will be set up. The first to duction in the costs related to the data acquisition determine the shading coefficients of the various systems in the field and also an appreciable improve- alternatives for use as reflective barrier under evalua- ment in the performance of the system as a whole, tion, and the second for the setting up of prototypes with the increase in the local processing capacity of developed for evaluation of the aspects of moun- the intelligent data acquisition units. ting and reduction in energy consumption in small air conditioning units. Fiber Optical 219 Silica Amplifiers Io – Intelligent Sensor Doped with Erbium 218 for Applications in the Electrical Sector Coordinator: Carlos Kenichi Suzuki Coordinator: Company: Bruno Abrantes Basseto Sun Quartz Indústria, Comércio e Company: Manutenção de Dispositivos e Equipamentos AdTS Engenharia e Automação para Área de Telecomunicações Ltda. p/ Setor Elétrico e Industrial Ltda. (ex-Optolink Ind. e Com. Ltda.) Approved value: Approved value: Phase 1: R$ 75,000 Phase 1: R$ 74,480 Phase 2: R$ 223,622 / US$ 12,700 The expansion of the Brazilian electrical sector has suffered a number of restrictions which bring it A large number of fiber optical amplifiers work close to its installed limit, operating under critical with silicon amplifying fibers doped with erbium. conditions. Faced with this, more effective automatic While Brazil has considerable industrial potential to monitoring systems have shown themselves to be es- produce standard optical fibers, erbium fibers are sential, with the support of advanced information still an imported product. Based on the long expe- systems, capable of assisting operators in generation, rience acquired by Integrated Quartz Cycle Labora- transmission and distribution. With the precise in- tory (LIQC) in VAD (Vapor-phase Axial Deposition) formation supplied by such sets of resources, the technology for the manufacture of silica preforms planning of investments or the programming of re- for optical fibers, this project proposes the develop- pairs can be carried out in a more efficient and effec- ment of erbium fibers following five basic stages of tive manner. The proposal to develop intelligent, so- VAD processing, considering this to be the most ef- call Io, sensors, dedicated to the monitoring of power ficient and economic manufacturing method: a) equipment, offers a very promising alternative to se- sourcing the porous silicon preform; b) doping with veral of the problems currently facing the electricity erbium by immersion of the porous preform in li- sector. The use of small, low cost data acquisition de- quid solution; c) thermo-chemical treatment for vices, installed in close proximity to the transducers drying, the elimination of hydroxyls and consolida- of the signals to be monitored, can appreciably sim- tion in totally transparent preforms free from micro-

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bubbles; d) make up of the mechanical jacket for lized personnel, since carcinogenic chemical rea- over-cladding; and e) pulling into optical fibers. The gents are used in the manipulation. The techniques methodology of doping with erbium (diffusion) will of immunological tests have shown results of high be carried out by immersion of the porous silica pre- specificity and sensitivity, do not present health risks form in liquid solution. A large part of the detail in to the manipulator and require simple and rapid the various stages of processing the preform will be steps for the diagnosis. In addition, they allow a carried out using the available infrastructure in much larger number of tests to be carried out at a lo- LIQC and in the Materials Engineering Department wer cost, leading consequently to a better control of of FEM. For the pulling of the fibers and their cha- grains, foodstuffs and animals foods. In phase 1 of racterization we will be able to count on collabora- the project, the standardization of an ELISA kit for tion from Xtal Fibras Ópticas and the Fiber Optics the detection of aflatoxin B1 was carried out by di- and Photonics Group of the Institute of Physics in rect competition, using commercially acquired mo- the State University of Campinas, UNICAMP. It is noclonal antibodies. In phase 2 the standardization interesting to point out that the high value added to of an ELISA kit will be undertaken using monoclo- erbium fibers, combined with the small volume of nal antibodies produced in Brazil, making this tech- production to meet demand in the country, offers nology accessible to a greater number of patients. another great advantage to the project. Both the phases of R&D (Phases I and II), and the commer- cialization stage will be able to be carried out using Graphical Model the already established infrastructure in LIQC. 221 of the Dependence between the Rules of Business and the Physical/Financial Development of an ELISA Kit Impact on Maintenance 220 for the Detection of Aflatoxine B1, Aimed at the Control of Grains, Coordinator: Foods and Animal Foods Denise Stringhini Company: Coordinator: Apyon Technology Ltda. Claudete Serrano Astolfi Ferreira Approved value: Company: Phase 1: R$ 49,244 Al-Tech Comércio e Importação Ltda. Phase 2: R$ 167,468 Approved value: Phase 1: R$ 62,227 The most critical stages of the development of Phase 2: R$183,890 / US$ 36,891.20 systems are their design and implementation. In the project, user interfaces, rules of business and physi- Mycotoxins are metabolytes produced by fungi cal models are specified. The rules of business are all which grow naturally and contaminate grains, ani- the calculations, assumptions, validations, procedu- mal foods and human foodstuffs. When ingested res and events of a system. These rules are specified they can cause varying levels of toxicity depending in natural language, normally without standardiza- on the type, the quantity of toxin, the species, the sex tion. Following this stage, they are sent to the pro- and the nutritional state of the animal. Besides this, grammers, who are going to transform the specifica- some mycotoxins, and particularly aflatoxin, have tions into source code in some programming been described as important carcinogenic, mutage- language. The main problem existing in this process nic, teratogenic agents or causers of estrogenic ef- is that the rules are inter-dependent and the analysis fects. The detection and subsequent control of con- of impact of a change in one rule is a repetitive, ma- tamination by aflatoxins are carried out by means of nual task, and prone to mistakes. Frequently the de- sensitive and specific analytical tests. Historically, pendence is not explicit, since it occurs only in physico-chemical methods such as high performan- certain specific conditions, which demands interpre- ce liquid chromatography (HPLC), thin layer chro- tation and knowledge of business on the part of the matography (TLC) and gaseous chromatography systems analyst. The objective of this work is to faci- (GC) are traditionally used for these determinations. litate the search for the dependencies of the rules of Although these methods offer a high level of repro- business, helping the systems analyst evaluate the ducibility, they are onerous, slow and require specia- impact of a business change, as much in the volume

Translating Research into Business • 169 of work required as in the number of physical and Company: human resources necessary. In phase 1 a functional Plastiviva Aplicações e prototype was developed of an application to show Reciclagem de Polímeros Ltda. visually the dependencies between the rules of busi- Approved value: ness and also the physical and financial impact of the Phase 1: R$ 72,600 alterations and evolutions in the specifications. In phase 2 this prototype will be finalized, documented There is ever increasing pressure in society not and totally integrated into Apyon Studio, which is a only in the sense of encouraging recycling but in de- productivity tool that permits specification at a high terring, by means of legislation, the deterioration of level of abstraction and also permits the generation the environment with heavy fines in sectors of the of the part related to the technology of an informa- economy such as producers of electric batteries and tion system. The result of phase 2 should be the chemicals/packaging, which pollute rivers and commercialization of a product to be integrated into streams. Our objective in this project is to develop Apyon Studio. the industrial procedure for breaking the chemical bonds responsible for the reticulation of plastics or rubbers by the application of high energies, such as Parallel Processing on the microwaves, ultra-sound and others. These techni- Internet or in Corporate Networks 222 ques are probably the most efficient, clean and eco- nomic process for recycling reticulates, since they Coordinator: break down the two-dimensional bonding scheme Eduardo Javier Huerta Yero of the reticulation, without depolymerization of the Company: polymer and permit new reticulation (or vulcaniza- Prógonos Consultoria & Comércio Ltda. tion) with properties equivalent to the original com- pound. In this case, the recycled material returns as Approved value: an active commodity. Very efficient for nitrilic rub- Phase 1: R$ 25,200 bers (NBR), neoprene (CR) and polymers which Phase 2: R$ 132,700 possess polar groups, this method uses doses of mi- crowave energy at a specific frequency and in suffi- With the advance of information technologies cient quantity for the effective de-reticulation of the and the development of computational infrastructu- polymer. The research developed for each applica- res, such as networks capable of interconnecting up tion leads to a process (sonic or microwave) always to millions of computers scattered throughout the combined with a concentration of chemical pro- world, we have at our disposal today enormous com- ducts (processing auxiliaries) with a dosage of putational resources at relatively low costs. The pos- around 2 per cent. It is sold at R$ 20.00 per kilo, sibility of using groups of computers in the search which represents a cost of R$ 0.40 per kilo of recy- for solutions to complex problems is today a palpa- cled material which, added to the costs of proces- ble and desirable reality. However, there are nume- sing, in general R$ 0.50 per kilo, amounts to a total rous difficulties in managing the processing of data of R$ 0.45 for a material with a virgin resin price of in mass parallel environments, also called computa- R$ 3.20 per kilo for EVA and which rises above R$ tional grids. In this research project, we propose the 8.00 for imports such as neoprene and EPM/EPDM. commercial development of a software platform ca- pable of managing an arbitrarily large group of computers in the sense of making them work coope- Development of ratively on the solution of complex problems. Such a Standardized Materials for platform will permit, in this way, the computational 224 the Manufacture of Herbal power latent in networks of computers of whatever Remedies and Vehicles dimensions to be taken advantage of and at low cost. appropriate for their Applications

Coordinator: Recycling of Luis Daniel Loyola Herrera 223 Reticulated Polymers Company: Coordinator: Multi Vegetal Ind. e Com. de Edson Ghilardi Cosméticos e Prod. Naturais Ltda.

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Approved value: dency, according to several pieces of research, is that Phase 1: R$ 41,820 this usage is primarily adopted by corporations, with various benefits in terms of agility and efficiency, The objective of this project is the development among others. Taking into account these parame- of standardized vegetable extracts from national me- ters, an e-learning solution with use of mobile inter- dicinal plants for use as materials in herbal remedies net will permit, in addition to mobility, more effec- and cosmetics and also for use in various kinds of tive training with lower costs. In this context, colloidal vehicles and their possible pharmaceutical Infosoftware Sistemas will develop a system of m- forms. Standardized extracts will be defined as those learning (distance learning with mobile communi- vegetable components which are of a defined origin cations tools) using cell phones and palmtops which and within the quality guidelines laid down by the can work on or off line. The main objective of this National Agency for Health Vigilance, Anvisa, and project is to develop, by means of research which the industrial and laboratorial manipulation of will also involve researchers from the area of distan- which adhere to operational procedures laid down ce learning, the necessary structure for this solution in norms accepted by the Ministry of Health and the to work. At the end of this study we will have a to- chemical standardization of which is established by tally defined solution ready to be implemented. With the application of known biological markers/active the implementation of this project, Brazil will oc- principles. In the first stage of the project five plants cupy an outstanding position in the international from the national flora will be studied: andiroba panorama, situated in the group of the countries (Carapa guayanensis); marcela (Achyrocline satu- most developed in the wireless area. In addition, the reioides); pau ferro (Caesalpinea férrea); carajirú project may open possibilities for the development (Arrabidaea chica); cherimoya (Annona muricata); of other solutions, involving people communication melão-de-são-caetano (Momordica charantia). Qua- and using these devices, which will increase the com- litative phytochemical characterization will also be mercial potential of the solution. done on extracts of each of the species and tests of formulations with these extracts in colloidal vehicles (creams, gels, lotions, syrups, and others). The work Clothes will be carried out on the company’s premises and in 226 Press the phytochemistry laboratory of the Institute of Chemistry in the Paulista State University, Unicamp, Coordinator: and the preliminary toxicological trials in the Pluri- Nicola Getschko discipline Center for Chemical Research, CPQBA, in Company: UNICAMP. Coll Projetos, Engenharia e Tecnologia Ltda. Approved value: Use of Mobile Internet as Phase 1: R$ 28,190 225 a Tool for Distance Learning Phase 2: R$ 182,954 Coordinator: This project aims at the development of a totally Luis Fernando Reis Tavares Pais new automated product, with low consumption of electric energy, innovating the process of pressing Company: clothes and decreasing user’s the time and effort on Infosoftware Sistemas this task. The operating principle of this equipment Approved value: consists of exposing the dry items of clothing, hung Phase 1: R$ 26,300 on appropriate hangers, to a constant flow of satu- rated steam combined with a pulling effect, when Businesses are looking more and more to invest necessary, so as to achieve the relaxation and the re- in the up-skilling of their co-workers, so as to increa- lief of residual tensions in the material fibers. Once se their knowledge base and achieve, through this, a the relaxation cycle is over, the stage of drying by competitive edge. Within this context, the use of e- forced convection follows, which is also intended to learning in businesses is increasingly more wides- maintain the micro-geometry of the fibers in the pread. With the emergence of mobile communica- material, obtained in the previous cycle. The relaxa- tions tools (palmtops and cell phones), the use of tion cycle begins with the generation of steam, in Internet via them has been ever greater. The ten- the lower part of the equipment, creating an up-

Translating Research into Business • 171 ward flow by natural convection, impregnating all noted in Brazil. It should further be highlighted that the items of clothing. A system for generating hot the software available on the external market is availa- air, installed in the upper part of the equipment co- ble in the English language, is not compatible with mes into action after the relaxation cycle, removing other types of assessment and has a cost which is still all humidity and completing the smoothing, obtai- considered high by Brazilian standards. ning in this way the final conformation of the items of clothing. In addition to being pressed, the clothes have been deodorized and made hygienic. The se- HIC TV – Facilitator for quence and the duration of the relaxation and dry- 228 Interactive Shopping ing cycles are controlled automatically, by means of via Television and Radio an electronic control system which operates in a closed grill. Temperature and humidity sensors pro- Coordinator: vide information to the control system which defi- Pedro Ricardo Drummond nes the time for each cycle. The operation, on the Company: user’s part is very simple, merely having to activate Digicall Eletrônica e Telecomunicações S/A the on/off button. The product is aimed at domes- tic consumers, hotels, hospitals and tailoring busi- Approved value: nesses, among others. Phase 2: R$ 199,308 / US$ 28,540

The present project aims to develop a device Software for the Study of (HIC TV) which will enable television and radio 227 Hazard and Operability transmission shopping, and interactivity in televi- sion and radio programs. The functions are carried Coordinator: out via high-frequency audio communication from Paulo Eduardo Pascon the receiving apparatus previously installed in a par- ticular place by the customer (TV and radio) to the Company: device that is the object of the present project. In this Processos - Soluções de Engenharia S/C Ltda. way, in a TV transmission in which a product is of- Approved value: fered for sale, the product information is transmit- Phase 1: R$ 13,680 / US$ 6,500 ted together with the audio signal (voice or music) Phase 2: R$ 204,999 of the advertisement. These signals are of a fre- quency close to the limits of human hearing and are The technique of identifying hazards known as the received by the device, which shows the product Study of Hazards and Operability, developed in En- name and its price in a liquid crystal display or on gland more than 30 year ago, is a recognized procedu- the TV screen, via its own character generator. If the re worldwide and its application in Brazil is increasing, user wishes to acquire the product, he presses a key principally in the chemical, petrochemical and oil and on the device, which in turn will raise an automatic gas sectors. It is one of the most comprehensive and purchase order or will initiate contact with the help systematic techniques known for assessing the safety desk of the company selling the goods, using the te- of manufacturing units and transport systems. Its ope- lephone line. Enabling interactivity, the device can ration is normally carried out on a word processor of be used for the measurement of TV or radio audien- the MS-Word type. However, given the characteristics ces, for the participation in question and answer of the technique, the time required for its application programs, and for the participation in TV or radio tends to be long and incompatible with the human re- surveys, amongst other applications. It is important sources that are normally available. In addition, the to point out that both objectives can be achieved wi- documents produced in this way are difficult to mani- thout the need for any high cost installation in the pulate and mix with other types of assessment, for user’s environment. No installation is necessary to example a quantitative risk analysis, increasingly de- special access to any data network, whether internet manded by the Brazilian regulatory agencies for the or any other, not even the replacement of the televi- purposes of environmental licensing. Some businesses sion set with another model. HIC TV is simple to abroad have now developed software for the applica- install, low cost and permits shopping users to enjoy tion of this technique, but nothing similar has been the advantages it offers.

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Integrated Project for Production Production of of Buildings – A New Methodology Concentrated, Sterile, Liquid 229 in Project Development 230 Culture Medium, for Cultivation of Leptospire Strains Coordinator: Rita Cristina Ferreira Coordinator: Rui Vadik Abrão Company: DWG Arquitetura e Sistemas S/C Ltda. Company: Approved value: Bio Pronto Indústria e Comércio Phase 1: R$ 41,947 de Produtos Biológicos Ltda.

The integrated project for the production of Approved value: buildings aims to meet the demand of the civil resi- Phase 1: R$ 67,269 dential construction market for a unique and har- monized project. It addresses a growing concern Leptospirosis is an urban disease, associated among construction companies and administrators with the presence of rodents, which appears with in the area of planning and product management, in greater intensity in large centers and mainly in the relation to the need to reduce costs, guarantee qua- rainy seasons (Silva, 1994; Ministério da Saúde, lity and increase competitiveness among businesses. 1997). It is an epizootic, which has a variety of sero- DWG Arquitetura gained significant experience in vars associated with some species of animals, as for this market through the development of the Ma- example, serovar canicola in dogs, serovar pomona sonry Project, which as it unfolded revealed the exis- in pigs, icterohaemorrhagiae in rodents and wolffi in tence of a demand for the evolution of the services bovine animals (Baranton et aI., 1995). Considering offered. Thus, from the Masonry Project, DWG pro- the importance of leptospirosis in our environment, gressed to the Partitions Project, which included the the present work aims to prove the technical viabi- integrated harmonization between various systems. lity of developing a formulated culture medium, At the same time the Masonry Project became con- containing proteins, vitamins, mineral salts and di- solidated as a Project for the Production of Parti- luent. It is important to highlight that leptospires do tions (for systems with block walls and plaster- not use sugar as a source of energy, so it is necessary board). With the present project it is intended to to replace it with another element. The production extend DWG’s experience in the development of re- of a culture medium, for the cultivation of leptospi- search into the production of the other systems re strains, in ready-to-use, concentrated, sterile, li- which make up the building, adding computational quid form, will be standardized and assessed for ste- procedures for automation, project control and col- rility and fertility against a battery of 22 reference laborative work between multi-disciplinary teams. strains of leptospirosis, approved by the World The objective is to generate an increase in quality Health Organization (WHO). The presentation of and efficiency in the planning and production of the the product in concentrated and sterile form will building. The result of the methodology of the pro- have all the indispensable nutrients for the cultiva- ject combined with the computational tools will tion of the bacteria, needing only to be diluted in constitute the Integrated Project for Production of sterile distilled water (Ph 7,3-7,4). The largest users Buildings, in a systemic manner. The specific re- of this culture medium are scientific research labo- search procedures in this first phase are: the collec- ratories belonging to public institutions, clinical tion of data on tools presently available on CAD and analysis and research laboratories established in databases, associated with internet resources which universities, and productive industries which pro- offer conditions for setting up collaborative tasks in duce vaccines. The intention is also to export the three dimensions, and the gathering of information product to businesses, research centers and univer- on construction techniques and systems practiced in sities in several countries. civil residential construction.

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Improvement and Expansion Company: 231 of Software Platform for National and Cyrbe do Brasil Ind. Química Ltda. International Dental Health Market Approved value: Phase 1: R$ 54,092 Coordinator: Sergio Aronis Brazil is considered one of the largest producers Company: of grain and fruit in the world, with agriculture one Aronis Engenharia e Sistemas of the most important bases of the national eco- Ltda (Dentalis Software) nomy. Nevertheless, some problems with fungi at- tacks, as well as a lack of infrastructure lead to con- Approved value: siderable losses of production in the course of Phase 1: R$ 74,708.70 cultivation, harvesting, transporting and storing. Phase 2: R$ 265,265 The growing resistance of phytopathogenic fungi to chemical fungicides has increased the consump- Dentalis Software has more than ten years’ expe- tion of these chemical pesticides in the control of rience in the development and commercialization of the fungi, causing serious damage to the environ- dental health programs in Brazil, with four products ment. The use of micro-organisms to control which cater for more than 8 thousand dentists. The phytopathogens could be direct, when the micro- market for dental services is in full expansion in Bra- organisms are used live, or indirect, by the applica- zil. Ninety-seven per cent of the population has ca- tion of their metabolytes. In both cases it is neces- ries and only 3 million people have dental plans, sary to source products which maintain the compared with 43 million with health plans. The ex- characteristics of the microorganisms or their me- pansion of dental services is occurring by means of tabolytes. Thus, these products need to be adequa- rising numbers of qualified dentists (14 thousand tely formulated to facilitate commercialization, per year), the increase in the number of dental transport, application and storage, without great health plans (more than 1 thousand) and the increa- changes occurring to their characteristics. The re- se in the number of dental plans taken out. There is sistance of metabolytes produced by Bacillus subti- currently no technological platform to meet all the lis to heat and the formation of highly resistant en- needs, including the requirements of the National dospores, are excellent characteristics for the Health Agency, ANS. Therefore, the aim of this pro- commercial development of formulations of this ject is to develop this technology to cater for the den- bacteria. In this undertaking, the objective is to tal health plan market, integrate the system for den- launch on the Brazilian market a biological product tal surgeries with the health plan systems and make for the control of pests and fungal diseases in agri- versions available in English and Spanish to cater for cultural crops and in post-harvested fruits of eco- the external market. In phase 1 of the work, the com- nomic interest. Processes were developed for the pany gathered information in the field and develo- production by submerged fermentation of a bio- ped and tested a prototype for market research, controller of phytopathogenic fungi derived from identifying in this way the majority of the require- Bacillus subtilis progeny, isolated from Brazilian ments of the system. Based on this information, in ecosystems, with proven antagonistic activity to- phase 2 of the project, it is intended to carry out the wards phytopathogenic fungi and mycotoxigens. improvement and expansion of this technological Currently we are testing the application of the pro- platform to cater for the demand of dental health duct for the treatment of several crop plantings. plans and multi-clinics. In addition to management functions, these processes aim to provide subsidies for the establishment and oversight of Preventative Policies in Dental Health. 12th BIDDING INSTRUCTIONS

Optimization of the Production SIGE - Integrated System 232 and Formulation of 233 for the Strategic Biocontroller of Phytopathogens Management of Business

Coordinator: Coordinator: Teresa Jacoba Cesare Vidaurre Arnaldo Ferreira Sima

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Company: re, indicating the moment at which that structure SIMA Internacional Indústria e Comércio Ltda. should be repaired. In this way, it may even forewarn of its collapse on account of corrosion caused by chlo- Approved value: ride in the metal framework of the structure. The Phase 1: R$ 6,562 main cause of this corrosion is the diffusion of chlo- ride ions within the structure. These ions occur in sea This project aims to develop an integrated sys- water and in the chemical materials used to melt ice tem with support tools for the activities of planning (de-icing agents) formed on bridges and roads in cold and managing business at the strategic, tactical and regions. The proposed sensor consists of an optical fi- operational level. The objective is to elaborate a sys- ber the whole length of which is entirely sensitive to tem which permits the complete integration of the- chloride ions, forming what is known as a distributed se activities, filling a space that exists in the informa- sensor. The sensor can be inserted into the concrete tion technology market. SIGE aims to establish a structure to detect the incursion of these ions. It con- management environment which allows the deci- sists of a glass nucleus and a covering made from a sion maker to monitor and simulate the evolution of fluorescent material, the spectroscopic properties of competitive scenarios and the performance indica- which are modified in the presence of chloride ions tors of the business, in a dynamic way and in real enabling the device to generate a diagnosis swiftly. time, on the basis of information that is both inter- nal and external to the organization. The system should also act as a facilitator in the process of esta- Development of New blishing strategies and concepts of management (for Technologies for the Multiplication example the balanced scorecard), in the presentation 235 of Bananas in High Volume Bioreactors of best business practice (templates and role mo- dels) and in the management of strategic knowledge Coordinator: in the organization. SIGE should operate integrating Clemência Noriega Söndahl the concurrent information of management sys- tems, of management information, of the support Company: tools for strategic planning and market information, Bionova Mudas e Plantas Ltda. and the other systems and databases within the or- Approved value: ganization. It should support the setting up of a stra- Phase 1: R$ 40,300 tegic/managerial management cockpit which allows Phase 2: R$ 46,868 the decision maker to monitor and simulate the be- havior of indicators and business scenarios. Brazil is a large producer of bananas, however the cultivation of the fruit is still practiced in the tra- ditional manner, using few higher quality in vitro Optical Fiber Sensors seedlings. The main objective of this project is to de- for the Detection of Chloride 234 velop a more efficient method of banana micro-pro- in Concrete Structures pagation and, in this way, make viable the availability of healthy seedlings for new plantings, at lower costs. Coordinator: Seedlings multiplied in vitro produce 30 per cent Claudio Oliveira Egalon more than conventional ones due to their better ori- Company: gin (selected plants) and their healthiness (being free C. O. Egalon Consultoria from systemic diseases). Another of this study’s ob- jectives is to evaluate the performance in the field of Approved value: banana seedlings produced in bioreactor, of seedlings Phase 1: R$ 72,610 produced in solid medium and of seedlings produ- ced by conventional ex vitro method. It is hoped in The company intends to develop, in collaboration this way to demonstrate the advantages and viability with the Chemistry Department of the Paulista State of a more efficient and cheaper multiplication of University (Unesp), in Araraquara, a new fiber optic healthy banana seedlings. Productivity and cost of sensor for determining the presence and concentra- production figures will be collected for the three tion of chloride ions in concrete structures. The sen- types of seedling being tested. The cost of manpower sor will have a spatial resolution of up to 5 millimeters is responsible for 60 to 70 per cent of the final cost of and will provide a reliable form of determining the in vitro seedlings. concentration of chloride ions in a concrete structu-

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PABX over ganization, to administer the structured part (tran- 236 Local Network sactional data) as well as the non-structured part (email and online publications) of the whole range of Coordinator: information provided for and consumed by the in- Dagoberto Agenor de Sousa ternal and external publics, is the great challenge for organizations which, like the banks, have a high usa- Company: ge of the Web environment. The corporate portal E+I Engenharia da Informação Ltda. emerges therefore as a model capable of overcoming Approved value: this difficult situation. An absolutely essential ele- Scholarship: R$ 19,542.60 ment of corporate portals is their capacity to provide an environment for the management of content. The This project aims to study the viability of cons- volume of content is growing explosively and affects tructing a PABX System over an existing local net- businesses as yet unprepared. The consequence of di- work, using Voice over IP, the telephone terminals of sorganization is one alone: the costs of publication which are linked to stations (personal microcompu- increase significantly and the customers are left dis- ters) and the control center of which is hosted on a satisfied. The object of this project is to specify a mo- server equipped with multiple interfaces with tele- del for a corporate portal for banks, which will also phone lines of the Public Switched Telephone Net- represent a non-functioning portal prototype, which work (PSTN) and, when the conditions exist, for a will serve as a basis for the development, by the com- quality connection, interconnected to the internet. pany, for a de facto prototype of this product. Ano- The project should lead to a Distributed PABX ther objective is the development of a business plan, System, the implementation of which takes advanta- with emphasis on the study of the market viability of ge of the local network of microcomputers existing the corporate portal for banks. in the companies for the purposes of reducing the installation costs and even justifying its economic advantage. Therefore, it is necessary to investigate, Production of Bio-Oil via within the ambit of the project, the technical limita- 238 Fast Pyrolisis of Agricultural tions of the components available in the businesses Waste for Use as Fuel and Materials and define the minimum technical requirements and other conditions for their taking advantage of Coordinator: the setting up of the PABX over local network. The Edgardo Olivares Gomez study should end with the implementation of a pro- Company: totype with a minimum configuration, in which the BIOWARE - Sistemas de basic features of PABX will be developed and tested, Termoconversão de Biomassa Ltda. making internal communication and connection to the fixed network the priority, including the existing Approved value: PABX, with the aim of verifying the technical viabi- Phase 1: R$ 70,224 lity of the project. The first phase of this project aims to carry out a technical evaluation for the production and com- Model for Corporate mercialization of the products obtained by fast 237 Portal in the pyrolisis, principally bio-oil, from renewable natio- Brazilian Banking Sector nal raw materials of vegetable origin (vegetable bio- mass). The Bioware pyrolisis process is versatile and Coordinator: uses technology of fluidized bed reactor on a pilot Eduardo Henrique Diniz plant scale with a nominal capacity of 100 kilos per hour of polydisperse biomass to heat and devolatize Company: rapidly the material particles, with the products of Hiperlógica Informática e Educação Ltda. the pyrolisis (gases, vapors and pulverized solids) Approved value: swept along by the same effect that produces the Phase 1: R$ 18,400 fluidization gas. In its first phase, the project envisa- ges the implementation of three groups of tasks ai- The building of an infrastructure capable of med at technical evaluation of the pyrolisis process. coordinating the internal and external flow of the or- The first group involves improvements to the reco-

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very and separation of liquids from the pyrolisis, Development of Machine from the burning of the pyrolisis gases and the mea- 240 for the Fusion and Traction of surement and control of operational and process va- Fibers for the Manufacture riables (temperature, pressure, composition and es- of Passive Optical Components cape of gases). The second group involves the technical evaluation of the pyrolisis process for the Coordinator: different operating conditions planned. The third Francisco Martim Smolka group should study, in a preliminary way, the socio- Company: environmental impact of the technology based on Optolink Indústria e Comércio Ltda. the results obtained for the different operating con- ditions planned. Approved value: Phase 2: R$ 236,600

Establishment of In the last few years a vast optical network has 239 New Space for Agricultural been built covering almost the entire world and Commercialization with Virtual which constitutes an infrastructure (backbone) on Reverse Auction - AGRO VIRTUAL which rates of the order of tens of gigabytes connect huge hubs. The next stages will be the access net- Coordinator: work to link large users and the subscriber’s optical Ernesto Fernando Rodrigues Vicente network. As the capillarity of this network increases, greater will be the consumption of optical compo- Company: nents. Despite the basic technology of optical cou- Deltacom Comunicações Ltda. plers having been developed from the scientific Approved value: point of view years ago, only today have relevant Phase 1: R$ 52,266 commercial applications begun to emerge in Brazil. The two main aims of this project are: first, to deve- The general aim of this project is the develop- lop a new heat source for the fusion and pulling of ment of a concept for the commercialization of the optical fibers. And secondly, to develop a traction productive chain of fruit and vegetable farming by drive for fibers, incorporating active control of the means of a technological tool which allows the use of pulling tension. In addition, the new equipment will the digital reverse auction format. In line with the have a more up-to-date control system, as well as world tendency, the initial focus of action is in the high precision mechanics and an optical monitoring area of perishables. The proposal is to build a virtual system in more than one wave compliment. The new trading exchange for the market garden industry, heat source will act by heat transfer through special dealing with supermarket chains, convenience sto- ceramics, so as to protect the fiber from direct inci- res, importers and exporters and even small regional dence. This source will allow better control and re- markets, without ignoring the first link in the chain duction of the hot zone, making it possible to make – the rural producer. The proposed electronic mar- components of a smaller dimension than the present ket with the creation of a reverse auction makes avai- ones. The active control of the tractioning tension of lable access to products and services of great com- the fibers will enable an improved performance in mercial and social impact, highlighting a new terms of losses, as well as mechanical reliability, by business model for the agricultural sector based on means of the knowledge and control of residual ten- the relationship of buyers, distributors and suppliers sions of the encapsulated fibers. in the same transaction space. The creation of the Space for Agricultural Commercialization with Vir- Development of tual Reverse Auction promotes the coming together Instrumentation for of the agents of production and the demand mar- 241 Optical Fibers kets, in a trading venue where the product, the dis- tribution and the commercialization occupy the Coordinator: same virtual environment of relationships which in- Ildefonso Félix de Faria Junior volve producers, buyers, sales promoters and profes- sionals from technical areas in joint, simultaneous Company: and synchronized actions. Optolink Indústrias e Comércio Ltda.

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Approved value: give guidance on programming procedures, cancel- Phase 1: R$ 50,000 lation and verification of the service. The user will Phase 2: R$ 299,800 not use specialized procedures to request any func- tion of the wake-up service. Requests will be made This project will progress the development of a verbally or by navigating between options offered by family of instruments for applications in the field the system. The connection of the Public Switched as well as in the laboratory. These instruments will Telephone Network (PSTN) to the equipment will be light sources and optical power meters with in- occur via subscriber line, trunk, PABX branch or a terfaces for access to computers. This functionality code or special number, depending on who is res- will permit the integration of these instruments, ponsible for the commercial exploitation of the ser- creating systems the applications of which will be vice. The connection of equipment to the PSTN will geared towards the supervision of optical networks, occur through automatic dialing of the number re- which could be telecommunications or cable TV or quested to receive a wake-up call. even industrial complexes. Such systems will have the capacity simply to carry out remote monitoring to check for the presence or absence of optical sig- Development of nal, or will also be able to transmit and receive 243 Multi-user Gas signals codified and transmitted by the MUX/DE- Chromatograph MUX optical interface, operating at rates corres- ponding to fractions of E1 (2 megabits per second). Coordinator: This project proposes the continuation of the deve- José Félix Manfredi lopment of the instruments and the study of cir- Company: cuits for conversion of electrical signals into optical Tech Chrom Instrumentos ones. The strategy will be centered on the develop- Analíticos Ltda. ment of parts (sources and receivers). Subse- quently, the work will undertake the integration of Approved value: the created elements. The integration of the instru- Phase 1: R$ 49,575 ments will be implemented by means of software to Phase 2: R$ 245,509 create systems with specialized functioning. The objective is to develop a benchtop prototy- pe of a gas chromatograph with the innovative fea- Universal ture of a removable column in a separate capsule. 242 Wake-up System The introduction of the encapsulated column com- bines the traditional advantages of the technique Coordinator: and the innovative features of an instrument which Jesus Raindo Gomez can be used without the operational restrictions found in traditional equipment. The capsule contai- Company: ning the chromatographic column will have an E+I Engenharia da Informação Ltda. entry connection and an exit connection for the en- Approved value: trained gas connected respectively, to the injector Phase 1: R$ 37,500 and the detector, by a shielded snap connector sys- tem manually operated, requiring no tool. The gas The Universal Wake-up System consists of the chromatograph will have a miniaturized heating development of a system, which is independent and system which will enable the direct heating of the external to the telephone exchange which will facili- column in the interior of the capsule. The confine- tate access to the wake-up service. Access to the ser- ment of the heat source will make the equipment vice will be effected from any type of telephone ap- safe for locations with a potentially dangerous at- paratus, fixed line or cell phone, simply by dialing or mosphere. The instrument applies the concept of keying in an access number to the service. On acces- separable capsule, containing the analytical column sing the service the user will initiate a normal tele- arranged in spirals, through the interior of which phone call which will be routed and end in the pro- the entrained gas (mobile phase) circulates, with air vision of an operator, attendant or Automatic at controlled temperature circulating between the Response Unit (ARU), equipped with attributes to spirals of the column. The small volume of the cap-

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sule will permit temperature gradients unattainable System for in conventional instruments, better control of the 245 Satellite Earth Stations thermal air bath, better reproducibility of program- of Natural Resources med conditions and rapid cooling. Coordinator: Leila Maria Garcia Fonseca Development of Integrated Company: System for the Production of 244 Gisplan Tecnologia de Geoinformação S/C Ltda. High Quality Strawberry Seedlings in Protected Cultivation Approved value: and Sterile Substrate Phase 1: R$ 67,808.64

Coordinator: This project’s main aim is to develop an architec- Keiji Roberto Nakashima ture for earth stations to process data transmitted by satellite on natural resources. The new series of Company: CBERS satellites, 3 and 4, will carry substantial tech- Plantech - Centro de Produção Vegetal Ltda. nological innovations compared with numbers 1 Approved value: and 2. Instead of continuing to make sizable inves- Phase 1: R$ 43,850 tments, as occurred with the first two satellites, to Phase 2: R$ 104,221 obtain solutions always dependent on the supplier, the National Institute for Space Research, Inpe, in- Strawberry production in Brazil is estimated at tends to invest in the modular system developed on 40 thousand tons, over an area of around 1500 hec- the PC+ Linux platform. The basic principle is to tares, with the State of São Paulo being the main use as much open software from the operating sys- producer. Almost all the production in the State is tem to the compiler, covering control tools for ver- done in the regions of Atibaia, Jarinu and Piedade. sion, management of modifications and bugs, inclu- Despite there having been an increase in the area ding the data base. In this first phase of the project planted, a drop in productivity has been noted, rela- simulations will be carried out to ascertain the pos- ted mainly to the unsatisfactory health of the plants. sibility of using microcomputers in the earth sta- The phytosanitary problems arise from the inade- tions. They will have to support a load of up to 150 quate management of some cultivation practices megabytes per second and carry out the process of such as soil preparation, irrigation and quality of formatting data, inventory and data transfer by mag- seedlings used. Strawberry is a crop that is fairly sus- netic medium in less time than two consecutive ceptible to diseases which attack the rhizome and sweeps of the satellite (around 100 minutes). The root system, caused by pathogens in the soil. Fresh earth station system will be modular in both senses: seedlings with bare roots originating in conventional functionalities and system sensors. As opposed to cultivations are a great disseminating agent of this the present case, the new system will permit the ad- pathogenic organisms (fungi and bacteria), which dition of new satellites or instruments, in line with can survive in the soil for long periods of time and the plug-in philosophy. affect new plantings. The present project aims to de- velop a production system in which seedlings pro- duced in vitro will be cultivated in a protected envi- Wind-up ronment and in a sterile substrate to guarantee that 246 Free-fall their phytosanitary quality is maintained when they Simulator are transferred to the field. The use of techniques of micro-propagation combined with the advantages Coordinator: of cultivation in a substrate without soil throughout Luciano Tanz the entire production chain of seedlings will avoid Company: contamination from soil. Starting with healthy see- Dynamis Indústria e Comércio Ltda. dlings should greatly minimize losses from disease, in addition to savings on defensives, thus reducing Approved value: the environmental impact. Phase 2: R$ 292,782

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The Wind-up Free-fall Simulator is a free-fall si- the washing of pieces between one stage and ano- mulator for people based on the generation of a high ther. The effluent with the metal impurities is trea- velocity ascending airflow. At present the 20 ton mo- ted conventionally through chemical precipitation, bile version is being built on a 15 meter long trailer an unprofitable and inappropriate process. This to which high efficiency, low noise, great mobility, work intends to develop and optimize an electro- safety and comfort will be added. Despite the exis- chemical reactor aimed at recovering gold from the tence of similar equipment, the combination of all effluents generated by the semi-jewel industry, re- these features in a single piece of apparatus was not placing the present chemical process. To do this, it possible until now due to technological limitations. is intended to place the metal with a high deposi- A vast national and international bibliography was tion speed in a region of potential/current in which collected on the subject of load in various wind tun- the reduction reaction will be controlled by mass nel elements. Assisted by parachutists, we also collec- transport, aiming to obtain a thick layer of gold ted a vast amount of data on jumps which, after and low adherence to the cathode surface. The low being processed by specially developed programs, al- adherence of the gold deposited will facilitate its la- lowed us to establish parameters for people weigh- ter mechanical removal, which will make it deta- tlessness in terms of weight, height, position and chable from the electrode surface. With this aim, it type of clothing. With this data it was possible to si- is intended to evaluate different materials for the mulate the tunnel on the computer and optimize its cathode in this type of process: stainless steel, cop- aerodynamic to improve energy efficiency. Propel- per and tin, among others. lers of 2.7 meters and 11 blades were specially desig- ned for this equipment, aiming for high efficiency and low noise levels. One of these propellers has now Development of Continuous been made. The design of the propeller and the 248 Process for Incorporation acoustics were done in conjunction and a sub-pro- of Vegetable Fiber in duct was created for the attenuation and insulation Thermoplastic Matrixes of low frequency sound. Wind-up is a cheap and safe means of training for sky-diving. Coordinator: Miguel Luis de Souza Company: Development of Equipment Newtech Assessoria, Consultoria e for the Electro-chemical 247 Prestação de Serviços S/C Ltda. Recovery of Gold from the Watery Effluent of the Bijouterie Industry Approved value: Phase 1: R$ 45,500 Coordinator: Luiz Carlos Ferracin The objective of this project is to develop a con- tinuous process for the incorporation of vegetable Company: fiber in thermoplastic matrixes. This innovation in- Realen Folheados Ltda. volves the development of two prototypes. The first Approved value: for a multifilament extrusion head and the other for Phase 1: R$ 47,230 a granulator of composites with vegetable fibers (si- Phase 2: R$ 105,595 sal fibers), also for multifilaments. These two pro- totypes are part of the development of an explora- In the city of Limeira, in the state of São Paulo, tory production line for the manufacture of is concentrated a national pole for the production composites with sisal fiber. The prototypes to be de- of bijouterie (semi-jewels), where around 400 small veloped aim to define design conditions for the head enterprises generate and discard, daily, industrial and matrix, as well as flow conditions of the mate- effluents with a high load of metals into the river rials (rheology). It is expected that the production Piracicaba. Generally, in the semi-jewel production line will be optimized and the composites produced process effluents are formed containing heavy me- will be characterized regarding their physico-mecha- tals (copper, nickel, zinc, cadmium and others) and nical properties. The mechanical properties should gold deriving from degreasing baths and metal pla- be improved, once the incorporation time of the fi- ting from the successive phases and the waters from ber into the thermoplastic matrix is fast enough, ta-

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king around one second. With this innovation, de- Multi-Satellite Modular FIEEL - gradation of the fiber caused by the heat and by the 250 Hardware for Control of a shearing is minimized, appreciably improving the fi- System of Uninterrupted nal properties of the composites obtained. The new Supply of Electrical Energy production system for these composites permits the direct use of injection molding, giving the finished Coordinator: product the desired format. Marcos Antônio Vieira da Silva Company: Eletro Máquinas Comércio e Representações Ltda. Development of Equipment 249 for the Electrochemical Approved value: Treatment Hospital Sewage Phase 1: R$ 74,700

Coordinator: The interruption of the energy from the Public Orlando José Bratfich Grid, RPEE, is a constant threat for small, medium and large consumers. The simple acquisition of a ge- Company: nerator with a motor does not do away with the Bluepoint Ambiental Ltda. threat of interruption of supply. The submitted pro- Approved value: ject aims to effect the automatic switching on/off of Phase 1: R$ 44,806 a generator and also carry out the automatic change- Phase 2: R$ 238,517 over between the energy coming from the Grid (RPEE) and the energy produced by the generator to Hospital sewage is composed of human dejecta meet a demand. The hardware was conceived to be which, since they are in an environment prone to easily installed in various pieces of equipment exis- the development of diseases, carry a high number ting on the market. Besides this, the project imple- of pathogenic and multi-drug resistant pathogens. ments two more innovative functions. The first con- Among them we can mention Staphylococos aureus cerns the monitoring and remote access for the and Enterococos faecalis. Also present in this effluent diagnosis, prevention and alarm in generator failu- is the water from washing contaminated materials res, allowing for the automation of the preventative and the waste from the cleaning of surfaces and maintenance of failures in the generator park instal- floors, among others, particular to hospital activity. led in the field. The second function concerns the in- The central aim of this project is to transform the telligence of the selection of loads in response to re- process of electrochemical and photo-electroche- quested demands. The project proposes that the mical oxidation of hospital sewage into a commer- control and activating functions of the generator cial process which: 1. does not demand the addition motor and the electro-mechanical or electronic of any chemical reagent or subsequent biological change-over of energy between the Grid and the ge- treatment; 2. does not generate sub-products which nerator be implemented by a proprietary applica- require new inertization treatments; 3. have a faster tion-specific integrated circuit (ASIC). Other func- kinetics than biological treatments; and 4. occupy a tions (for example, remote communication) should smaller physical space. In phase 1 of the work, elec- be carried out by commercial circuits, among them trochemical technology was applied for the treat- microprocessors. ment of sanitary sewage deriving from the Center for the Complete Care of Women’s Health, annexed New Support System for to the Hospital de Clínicas of the State University Decisions on Prices, of Campinas, Unicamp. The results were excellent 251 Quotations and Costs for and promoted the inactivation of the pathogeny Small and Medium Enterprises present in the solution in 10 minutes, using a low density of current. In the second phase a station Coordinator: will be built for the electrochemical treatment of Reinaldo Pacheco da Costa the hospital sewage at the same Center, which will remain in operation during the two years of the Company: project. PPE Engenheiros Associados S/C Ltda

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Approved value: ce a carbon-carbon composite which retains no tra- Scholarship: R$ 19,542.60 ces of the components of those resins, forming car- bon block which produced in this way is suitable for This project aims to develop models and algo- the use of the treatment of water for human con- rithms for optimization in the areas of applied eco- sumption. The proposal is also to define the adsorp- nomics, finance and production engineering with tion properties, of this carbon block, of organic che- interest in the management of operations in small mical compounds which may be contained in waters and medium enterprises. The proposal aims to study supplied for consumption by treatment stations. In the technical viability of reformulating the costs and Brazil, lack of knowledge concerning levels of these prices management system (POCR), already develo- contaminations is considerable, but certainly they ped by PPE Engenheiros, to make it more flexible are bound to exist in a high degree and are derived and less specialized. This involves a task that will re- from high levels of pollution caused by agricultural quire a certain technological effort, since the inten- defensives carried into the rivers from which many tion is to make operational models and methods of cities take their water for human consumption. considerable complexity, namely the models of acti- vity based costing (ABC). The broad objective is to permit small and medium industrial enterprises to be Biocompatible able to model a customized costing system for their 253 Metal Implants needs and to be able to draw from it relevant infor- mation for their financial management. The focus is Coordinator: not just on the development of conceptual models, Spero Penha Morato but also on the analysis of real cases. Phase 1 of this Company: project includes, among its main activities, techno- Lasertools Tecnologia Ltda. logical research and the collection of data on small industry, the research into models of financial ma- Approved value: nagement practicable in small and medium indus- Phase 1: R$ 16,690 / US$ 15,050 tries and research into applications currently availa- ble on the Brazilian and international markets aimed The objective is to develop methods and proces- at medium and small businesses to ascertain which ses for the manufacture of biocompatible metal im- aspects are covered today by existing solutions. plants using laser. In the short term, this innovation is focused specially, but not exclusively, on five pro- ducts: stents (vascular dilators), distractors (bone Production of a lengthening), titanium meshes, clips for aneurysm 252 Porous Body by Means of and spinal implants. With the results of these deve- Agglomeration of Fines lopments, the intention is to nationalize the manu- of Active Carbon, to be Used facture of these components aiming to offer high as Filter and Absorbed quality products at a lower price than similar impor- in Water Treatment ted products. In the medium term efforts will be di- rected toward the flexibility offered by manufacture Coordinator: by laser, allowing for new alloys and new designs to Silvio Benedicto Alvarinho be tried out quickly, using our CAD/CAM skills also for treatments which permit the insertion of medici- Company: nes, or even the use of radioactive alloys. Elementos Filtrantes Prisma Ltda. Approved value: Phase 1: R$ 28,750 13th BIDDING INSTRUCTIONS

The aim of this project is to develop a process for the production of porous bodies made up from the Research on Fuel agglomeration of active carbon fines (carbon block). 254 Purifier Device The proposed process uses as binder phenolic resins and, by thermal treatment at high temperatures, Coordinator: promotes the carbonization of these resins to produ- Alberto José Schmieliauskas

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Company: 7) to produce diagnoses in relation to quality of ser- Pentagrama Desenvolvimento vice offered, enabling the quality indices laid down de Processos e Projetos Ltda. by the National Telecommunications Agency to be calculated. The main elements to be developed are: 1) Approved value: signaling Processor PS-64; 2) pre-processing node Phase 1: R$ 31,715 software (BD-Pre); 3) post-processing node software (BD-Post) and centralized CDR database (Call Detail Owing to limitations in the transport and storage Record); 4) software for consultation and report ge- process of diesel, fuel is exposed to contamination neration (HORUS). In addition to the development with solids, such as rusting, and with liquids, mainly of these elements, studies will be undertaken relating water in condensed and emulsified form. In addition to the scalability, modularity, redundancy and relia- to causing environmental problems, these contami- bility of the computers (BD-Post) that will process nations affect the efficiency of the combustion and the signaling messages to generate the CDR and the also decrease the useful life of the injection and explo- centralized CDR database. This stage of the project sion system, such as the injection pump, fuel injectors also envisages the acquisition of five Remote Unit and combustion chamber. After 30 years studying the (RUs) kits consisting of equipment items CE nx64, phenomenon, a filtering system capable of keeping PS-64 and BD-Pre in order to carry out tests alongsi- back the water mixed in with the fuel was developed de operating companies. Owing to the size of the and patented. The separation principle takes advan- centralized data file (in the order of tens of teraby- tage of the bipolar characteristic of water molecules tes), it should be the object of internal tests and with using a chemically ionized filtering element. In its first several operators so as to guarantee its good perfor- stage, the objective of the research, based on the pa- mance when working at full load. tented filtering technology, is to prove that the filte- ring element bathed in the selected chemical produ- ces the desired effects of separation of solid particles and liquids (water) from the diesel oil, in an environ- Computational System for ment that simulates the discharge and the pressure of 256 Reduction of Losses in Energy a working diesel engine. For this purpose, controlled Distribution Networks tests will be carried out in purifiers constructed in the with Virtual Reality Interface laboratory, using commercially available materials, without legal and environmental restrictions and at a Coordinator: market compatible cost. Antonio Valério Netto Company: Cientistas Associados, Comércio, Network Representação, Consultoria e Treinamento Ltda. 255 Quality Management System – HORUS Approved value: Phase 1: R$ 19,079.90 Coordinator: Aldemar Fernandes Parola The focus of this project is the development of a computational system for the reduction of losses in Company: energy distribution networks (urban networks) by AsGa S/A means of advanced computational algorithms of cir- Approved value: cuit reconfiguration. The results deriving from the Phase 2: R$ 237,763 application of this system should be, among others, an increase in billing for the energy distribution This involves the development of a specific mana- companies and better use of the energy generated in gement system to gauge the quality of a network of the country. It is estimated that the Brazilian energy telecommunications services, as well as to compile distribution segment dissipates 52 per cent of the to- information which might permit the elimination of tal losses of the system, at an annual cost of around losses of income related to faults or frauds and serve 1.5 billion dollars. The development of computatio- as a support tool in the process of planning and deci- nal algorithms to reduce these losses by means of the sion making. This system uses information obtained reconfiguration of the network is extremely com- by ordinary signaling connection control (CCITT Nº plex. In this context, it is proposed to apply the Evo-

Translating Research into Business • 183 lutionary Algorithm with Representation in Graph tion. Since the application of the generator is aimed Chains (EA with RGC) (Delbem, 2002), to solve the mainly at charging batteries, an electronic power problem. EA with RGC has proved to be capable of rectifier circuit and a tension regulator will also be drawing up adequate restructuring plans for relati- designed and tested. vely large networks, using small computing times. Besides this development, an efficient man-machine interface is extremely important to drive the work Integrated Computational with a large quantity of data generated by a distribu- 258 Platform for Teaching, tion system and to facilitate the interpretation (as- Research and Development of sessment) of the solutions proposed by the system. Telecommunications and The proposed interface is based on Virtual (immer- Electronic Instrumentation sive) Environments, which have brought about huge revolutions regarding man-machine relationships Coordinator: both in the solution of scientific problems as well as Dalton Soares Arantes industrial ones. Company: Treinamento Consultoria Projetos e Pesquisa em Telecomunicações Ltda. Development 257 of a National 5Kw Approved value: Aerogenerator Phase 1: R$ 66,600

Coordinator: The aim of this project is to develop an integra- Cassiano Nucci Paes Cruz ted and reconfigurable computational platform for teaching, research and development in telecommu- Company: nications and electronic instrumentation. The me- Eletrovento Ltda. thodology comprises the initial prospecting and de- Approved value: tailed examination in search of information on Phase 1: R$ 37,069 possible solutions offered on the market. There will be a comparative study of sensors, AID and DIA The objective of this project is to develop a 5 ki- converters and the available interfaces. It is intended lowatt aerogenerator, the market potential for which to design and develop a basic prototype and to un- is estimated at 70 thousand units in the country. The dertake a search for possible applications based on initial phase of the project will involve the technolo- the proposed platform, which will be developed in gical development and prototype tests (proof of later stages. The methodology to be followed also technical viability) of the two essential parts of the envisages laboratory tests to prove the technical per- aerogenerator: the design for the propeller and the formance and the drawing up of a business plan. electricity generator. The second phase envisages the Two high performance computers based on the Pen- production of the best-in-class model for which the tium 4 will be made available for the development of other parts of the wind generator will be designed, the initial prototype of the platform. Signal acquisi- based on technology being developed by Eletroven- tion boards WR-1550i, PCI-DA4020/12 and NI 5911 to. In the area of aerodynamics, using WingAnalysis will be purchased. The anticipated result of the first Plus software, all the surfaces of the blades will be phase of this project is proof of the technical and designed in CAD. A prototype on a reduced scale economic viability of the platform to be developed. will be built in fast-prototyping machines, since in In this ambit, it is hoped to define specific niches in real size it should measure around 6 meters in dia- the telecommunications market for products based meter. This prototype will be tried in the field for the on the platform, such as test instruments for com- collection of data on rotation curves and torque in munications systems. relation to wind velocity. In the area of electric ma- chines, a generator will be designed with permanent magnets with several poles (probably 18) so as to be Wireless Optical efficient at low rotations (300 to 1000 rotations per 259 Communications System minute), atypical for electric machines. A prototype will be built to be tested on a bench that has a varia- Coordinator: ble speed motor which simulates the propeller ac- Elso Luiz Rigon

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Company: munity) only very approximately, or merely so as to FiberWork Comunicações Ópticas Ltda. minimize the problem in situations in which diffe- rent body masses generate similar signals. To get Approved value: round this problem, a new hybrid concept called Phase 1: R$ 36,500 / US$ 11,500 wave front coding is used. This combines optics and electronics aiming for an improvement in the sys- The objective of this project is to develop in Bra- tem’s performance and reducing the final cost of the zil fiber-less optical communications systems. Com- product. In phase 1 of this project the bench top pro- munications systems for applications in telecommu- totypes for the presence detectors should be assem- nications access networks, cell phone backhaul bled, to show the technical and economic viability of networks, interconnection between company LANs the idea. In phase 2, the sensor will be encapsulated and internet access providers. The system will opera- with the technologies developed in the first stage, te at a transmission rate of 2 megabits per second bearing in mind the assembly line processes already (Mb/s), in the window of 1550 nm, with reach from existing in the company. At the end of the project, the 500 meters (phase 1 of the project) up to 4 kilome- intention is to have mass production of the sensor ters, with 98 per cent availability. In the future, sys- and to launch it on the market by means of an appro- tems with higher rates, such as 8 Mb/s and 34 Mb/s priate marketing strategy. Even with the inevitable will be developed. Free Space Optics (FSO), or opti- increase in its price, it is believed that the innovative cal communication without fiber, is growing and imbedded technology will be quite superior, so that will occupy a prominent position in the next few the product will still remain competitive. year, as it transforms itself into the main alternative to broadband access in metropolitan environments. Probably, it will surpass radio systems and, in many situations, fiber optics. FSO systems of higher rates Band S Transmitter are more competitive today, since the alternative 261 to Integrate Doppler would be fiber, which is much more expensive and Meteorological Radar System involves licenses and high installation risks. Low rate FSO systems could also enjoy similar success. In this Coordinator: case, they would unseat radio access systems. It is in Jean Claude Lamarche this niche that FiberWork seeks to position itself Company: with the proposal of this technological development Omnisys Engenharia Ltda. project. The rate of 2 Mb/s (E1) was chosen for the initial project in response to market demand. Approved value: Phase 2: R$ 167,228

Development of New The objective of this project is to develop a band 260 Infrared Movement Detection S radar-transmitter and integrate it to the Doppler Sensors for Domestic and Meteorological Radar System under development in Business Security Applications Omnisys and to propose a modernization solution for all the obsolete radar systems currently installed. Coordinator; The classic radar-transmitter consists of four funda- Giuseppe Antonio Cirino mental modules: the synchronous generator, the po- wer supply, the pulse modulator and the high fre- Company: quency emission element. Classic modulators use a Eletroppar Indústria Eletrônica Ltda. delay line as an element for storing energy. Although Approved value: reliable, they only have a single pulse length per de- Phase 1: R$ 73,649 lay line, as opposed to the need, in many applica- tions, for this parameter to be easily adjustable. The This project aims to develop and manufacture modern solution for this deficiency was to develop a new passive movement detection sensors. In the radar-transmitter entirely in solid state. Transmitters world market, many of these sensors do not operate of this kind are, however, extremely expensive when in a robust manner in the detection of standards of compared to the classic ones and hardly viable for ci- variable sizes, as, for example, the silhouette of a hu- vil applications, especially for the market in focus. man body or of small to medium size animals. Sen- Therefore, the intention is to explore the low cost sors on the market today carry out this task (pet im- and high reliability of the magnetron-type emitter,

Translating Research into Business • 185 developing a commutation circuit which does away amplified and, by means of a mixer which emits a with the use of delay line and enables easier regula- pulse between the FI and the COHO signal, the sig- tion of the length of radar pulse. nal for linear videos I and Q is extracted which are in phase quadrature to resolve problems of ambiguity. Due to the fact that the Magnetron valves alter their Band S Receiver oscillation frequency with the passage of time, an 262 to Integrate Doppler AFC (Automatic Frequency Control) circuit is requi- Meteorological Radar System red which, by means of a comparison between the frequency transmitted and that of the local oscillator, Coordinator: ensures that the FI frequency is maintained at 30 Jorge Hidemi Ohashi MHz; if there is any alteration, an error signal is ge- nerated. There are two possible ways to maintain the Company: FI frequency. The first is to use the error signal gene- Omnisys Engenharia Ltda. rated by the AFC, adjust the Magnetron, and correct Approved value: its transmission frequency; and the second is to use Phase 2: R$ 250,092.40 the error signal generated by the AFC and adjust the local oscillator correcting its frequency. The receiver The basic objectives of this project are: to develop to be developed will use the option of correcting the a band S receiver to integrate in the Doppler meteo- frequency of the local oscillator. rological radar system, under development in Om- nisys, and to set up a team that is specialized and trai- ned in the development of new products which Administration and Integration of involve similar knowledge to that acquired during 263 Information for Decision Taking on the implementation of the project. The classic radar Enterprise Resources in Small and receiver is of the superheterodyne type with phase Medium Businesses, Using Automated coherence and the use of linear amplifiers for the Management Tool, Providing extraction of video signals. The transmitted signals Diagnostics and Administrative which return to the receiver present very low ampli- and Operational Agility tudes and are amplified by a low noise amplifier which is characterized by a high gain and low noise Coordinator: figure. This signal is then amplified and converted José Antonio Neves into an FI frequency of 30 megahertz (MHz) by Company: means of a mixer which emits a pulse between the AES - Application Express System S/C Ltda transmitted frequency and that of a high stability lo- cal oscillator (STALO). The frequency of the local os- Approved value: cillator can be syntonized 30 (MHz) above the trans- Phase 1: R$ 31,672 mitted frequency (supradyne) or be syntonized 30 (MHz) below the transmitted frequency (infradyne). In the struggle for market share companies must, The mode of operation to be used in the present pro- increasingly, search for greater agility in the proces- ject is supradyne. Phase coherence is also very impor- ses of decision taking, in order to make their pro- tant during the process of extracting the video sig- ductive systems more efficient and provide products nals. The synchronous transmission signal which at competitive costs. Considering the huge amount marks the start of the transmission and the cadence of information involved, it is necessary to create me- of the radar’s interrogations is present in the receiver chanisms which permit diagnoses to be obtained, in so as to synchronize the video extraction. This real time, and even simulations of operational con- synchronous signal is used as a reference of the oscil- ditions so that decisions are more appropriate and lation circuit in 30 MHz known as COHO (oscillator potentially more lucrative for the business. Large coherence), in order to maintain the same phase of companies invest millions of reals on establishing the transmitted signal. In the logarithmic amplifying and contracting specialized systems and services circuit the FI signal is amplified and the logarithmic which assist not merely in managing their busines- video signal extracted which is used to generate the ses. The object of this project is to demonstrate the AGC (Automatic Gain Control) used to centralize technical viability of the development of a specialist the linear amplifier’s dynamic so as to control the automatic solution in the administration of enter- gain. In the linear amplifying circuit the FI signal is prise resources with the characteristics of being easy

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to use, of low cost, compatible with the budget of Radio-controlled small and medium companies. Focused on the busi- 265 Agricultural ness segment and adapted to the developmental Model Plane aims of the contracting company, the project will de- velop an administrative tool based on software spe- Coordinator: cialized in decision taking, an infrastructure related José Roberto Rasi to applications aimed at data capture in existing sys- Company: tems, and develop small programs for the manage- Prince Air Models Ltda. ment of strategic information. Approved value: Phase 1: R$ 75,000 Development of Phase 2: R$ 244,865 / US$ 10,020 264 Thermoluminescent Dosimeters This project aims to develop a radio-controlled agricultural model plane for the spraying of agricul- tural defensives, distribution of seeds and similar Coordinator: operations on rural properties. The model plane will José Carlos Borges be built from a composite (fiber glass, reinforced Company: with mixed carbon and aramide fibers and epoxy re- MRA Indústria de Equipamentos Eletrônicos Ltda. sin) with a balsa wood frame, powered by a two- Approved value: cylinder petrol engine with electronic ignition con- Phase 1: R$ 56,940 trolled by a radio control system, with nine channels Phase 2: R$ 81,260 / US$ 30,033.50 and dual receiver, powering high-torque digital ser- vomotors. The spraying system will initially have a 25-liter reservoir for defensives, with prevision to in- This project aims to industrialize a product that crease the capacity as the project is refined. The au- is compulsorily used by more than a dozen direct tomatic flight stabilization system is envisaged as users, namely the institutions which provide radio- using a digital gyroscope with two axes which will logical monitoring services, and around 50 thousand automatically correct the flight, avoiding variations indirect users: workers exposed to ionizing radia- in the plane’s altitude. The project also includes an tion. The principal means of controlling these expo- automatic flight steering system to align the plane so sures is the individual monitoring and vigilance over that the spraying can be carried out in strips of ter- levels of radiation in work areas by means of detec- rain, without overlaps or missed areas, with the use tors called dosimeters. The most commonly used of GPS (Global Positioning System) and micropro- currently are made from thermoluminescent mate- cessors on board. In the second phase of the project rials, known as TLDs, the only manufacturer of two more planes will be built in composite, reprodu- which in Brazil is the Institute of Energy and Nu- cing the model demonstrated to be viable in phase 1. clear Research, Ipen, with which MRA has signed a The planes will be used for the development of flight technology transfer agreement. In the first phase of control software and studies of spraying. the project, innovations were concentrated on the solution of common obstacles to technology trans- fer processes which, in the case of CaSO4:Dy pellets, Band S Antenna Set include aspects such as the assembly of installations 266 to Integrate in Doppler and equipment in the pilot plant, the chemical tech- Meteorological Radar System niques of obtaining the raw materials that make up the pellet and the quality control of the thermolumi- Coordinator: nescent characteristics of the dosimeters. The second Luiz Manoel Dias Henriques phase will confront the technological problems cur- rently experienced by those dosimeters, among Company: which the sourcing of a more transparent and stable Omnisys Engenharia Ltda. aggregating material (gels that can vitrify) to carry Approved value: the thermoluminescent crystals, the incorporation Phase 2: R$ 285,904.60 of new dopants for refinement of the radiological sensitivity and new thermic treatment techniques to The objective of this project is two-fold: to deve- optimize the reusability of the dosimeter. lop a band S radar-antenna set controlled by a digi-

Translating Research into Business • 187 tal servo mechanism with a view to integrating it tions; 3) development of different types of formula- into the Doppler Meteorological Radar System un- tions; 4) assessment in the field of agronomic effi- der development in Omnisys, and to propose a solu- ciency of the selected formulations. In phase 1 of the tion for all the obsolete radars currently installed. project alternative and low-cost products were cho- The quality of the information received by the an- sen (sugar cane molasses, glycerin, yeast extract and tenna depends on its speed of rotation, on the preci- beer yeast) for the composition of the liquid culture sion of its positioning, on the parameters of the ra- media, with a view to the large scale production of dar pulse and on the gain characteristics, angular different structures of the biological cycle of Meta- aperture, secondary lobes and beam format. One rhizium anisopliae. This information will be used in great difficulty found in the design of radar antenna phase 2 for the development of new bio-insecticide sets was guaranteeing the information received with formulations based on blastospore and dry mycelia the increased gain from the antenna. This increase to enable the use of mycelial mass as inoculum in bi- entails the use of ever larger, and yet more unstable, phasic systems of production of airborne conidia. reflectors. Antennae with variable electromagnetic field came to be used in high power applications which demanded great precision. This solution, has Biomaterials Based on shown itself, however, to be economically unviable 268 Phosphates of Calcium Collagen for civil and short-range radar. The advent of digital for Reconstitution of Bone Tissue technology allows for the adoption of new electro- mechanical micro-processed solutions which gua- Coordinator: rantee, at a low cost, high precision in the antenna’s Marcos Roberto Bet movement. The project seeks, however, to study new Company: electromechanical solutions for the support of an- Pro-Line Serviços Produtos tennae and servo-mechanism controls, and to deve- Odontológicos Ortopédicos Ltda. lop a new radar-antenna set using digital technology. Approved value: Phase 1: R$ 36,480 Development of Bio-insecticide 267 Formulations Based on The aim of this project is to develop ceramic- the Entomopathogenic Fungus and collagen-derived materials in the form of mem- Metarhizium anisopliae brane for use in mouth-jaw-face reconstruction. Its indication is associated with bone defects caused by Coordinator: the very pathology itself and/or by surgical treat- Marco Antonio Tamai ment which results in defects such as bone cavities, mucous bone dehiscence, and gingival retraction as- Company: sociated with chronic inflammatory processes of the Bio Soja Industrias Químicas e Biológicas Ltda. jaws, such as cysts, granulomas and other tumors. Approved value: The proposed materials may also benefit patients Phase 1: R$ 17,580 with indication of tooth extraction and indication of Phase 2: R$ 183,300 / US$ 7,228.93 immediate dental implant with concomitant need for graft. The ceramics proposed in this project are The use of Metarhizium anisopliae for the control derived from salts of calcium phosphate and corres- of Mahanarva fimbriolata (Stal) in the cultivation of pond to: 1) non-stequiometric hydroxyapatite (HA) sugar cane in the state of São Paulo has greatly in- for application in bone tissue reconstruction of creased over the last years. The objective of this pro- small volume defects, and which in the form of ject is the refinement of current techniques and the green cake (raw preparation of HA) will be obtained development of new production and formulation by synthetic process, to replace similar materials processes for Metarhizium anisopliae, produced in li- which contain B-TCP and HA, the cost of which is quid and solid culture media, so as to raise levels of higher in relation to processing; 2) biphasic ceramics quality control and lower costs of production. To do (BCP) made of non-stequiometric B-TCP:HA this the following stages were outlined: 1) selection of which, on account of significant differences in solu- complex and low-cost culture media, as well as sour- bility, allow for the formulation of ceramic prepara- ces of nitrogen, carbon and vitamins; 2) evaluation of tions more suited to the volume of the reconstruc- the toxicity of inerts for liquid and solid formula- tion of tissue simply because of the variation in the

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proportion of the two hemihydrated ceramics; and Approved value: 3) injectable ceramics intended for mouth-jaw-face Phase 1: R$ 64,080 reconstruction to minimize ceramic migration. The proposal is to develop a process for produc- tion on an industrial scale of expanded starch foams Computational for biodegradable packaging. The main deficiency in 269 Analysis of Genetic the technology of current processes is the sensitivity Paternity Test of the product to liquids, which precipitate imme- diate biodegradation and the destruction of its me- Coordinator: chanical properties. Starch’s ability to absorb water Martin Ritter Whittle and its sensitivity to hydrolysis cause a big problem for large scale automatic production, as they make it Company: difficult to formulate a stable raw material, which Genomic Engenharia Molecular Ltda. can yield reproducible expansion results. The project Approved value: proposes the development of a starch foam with Phase 1: R$ 74,834 greater possible level of expansion, lower cost of production, totally soluble in water and biodegrada- The genetic paternity test aims to establish whe- ble, preferably free from artificial additives, and also ther a certain individual, the claimant, is the child of an adequate covering based on fatty and aqueous a second individual, the respondent. The tests most products. The processing equipment for the foam commonly applied in the courts today use DNA that will be designed and built by the project does (Deoxyribonucleic acid) to assess the probability of not exist on the national or international market. family relationship in disputed judicial paternity ca- ses. Nowadays there is a vast literature on cases on which genetic material of the respondent is availa- Establishment of Unit for ble. In the absence of this information, there are few 271 Recovery of Foundry references in the specialized literature. The doctoral Sand Contaminated by thesis of Luiz Montoya-Delgado addressed this pro- Phenolic Resin by Heat Process blem, but despite the technical advance it represen- ted, specific cases were described for which specific Coordinator: techniques were presented. The objective of this Silvio Benedicto Alvarinho work is to develop an automatic calculation tool which encompasses every type of judicial request Company: and which will be efficient even on a large scale and Metalurgica Piacentini & Cia Ltda. with data obtained from individuals with different Approved value: degrees of kinship. The main activities will be: 1) use Phase 1: R$ 75,000 of bayesian nets for modeling and calculation of the probability of paternity; 2) development of a here- The metal casting industry in Brazil is beginning dogram-bayesian nets compiler; 3) computational to take steps to reduce the negative impact of its ac- and mathematical treatment of the mutations in mi- tivity on the environment. Efforts in this direction cro-satellites (STRs-Short Tandem Repeats); and 4) stem, in good part, from the recent passing of a new hardy-weinberg equilibrium test, by means of a new environmental law which lays down more severe pu- methodology of tests of exact hypotheses. nishments, but undoubtedly they are also related to a new vision on the subject on the part of business owners. The other consideration which should en- Development of courage foundries to look for means to regenerate Foams Based on Starch and 270 the sand they use in their manufacturing processes is Their Application as the high cost of waste, which hovers around R$ 70.00 Eco-sustainable Packaging per ton. In this project it is intended to design and establish a demonstration unit with a capacity of up Coordinator: to 1 ton per hour, for the recuperation of foundry Patrícia Ponce sand contaminated with phenolic resins. Initially, an Company: assessment should be undertaken in the region of CBPAK - Embalagens Eco-Sustentáveis Ltda. Piracicaba, on the fate of the foundry sand contami-

Translating Research into Business • 189 nated with phenolic resin. The sand will be classified Company: in accordance with Norm NBR 10004, in addition to NovoFilme Componentes para Sistemas classification studies regarding the sublimation and de Energia (ex-V.S. Ferreira Consultoria) decomposition kinematics of the phenolic resin. It is Approved value: also intended to carry out the physico-chemical cha- Phase 1: R$ 68,850.77 racterization of the foundry sand using conventional analysis techniques, such as the use of the radioacti- The project aims to refine two different formula- ve tracer technique to check on changes in the size of tions and the applicator equipment for aqueous the sand particles contaminated during the heat polymeric emulsions with added graphite which, af- treatment, making it possible to evaluate the effi- ter drying, result in electrically conductive films, im- ciency of the proposed process. permeable to ions or gases, thermically and chemi- cally resistant for use in alkaline batteries and fuel cells. Formulation One will allow the replacement of Project for Frequency Filters solvent based films used in the alkaline battery in- Using SAW Technology for Application 272 dustry for the internal coating of the nickeled steel in Cell Phone Repeaters casing, preventing the corrosion of the cathode col- lector. Such batteries have a heavy demand in the la- Coordinator: test generation of electronic devices such as mini- Serguei Balachov discs, CD-players, digital cameras and electronic Company: organizers. Variations of the properties described, AsGa Engenharia e Representações Ltda. applied in Formulation Two, will permit the reduc- tion in the thickness of the present carbon/graphite Approved value: bipolar separators used in fuel cells. These separators Phase 1: R$ 72,900 collect and conduct the current from the anode of a cell to the cathode of the adjacent cell, while they The objective of this proposal is to develop a soft- also distribute hydrogen gas over the anode surface ware project for the analysis of the secondary effects and the air or oxygen over the cathode surface. The of SAW filters with a high degree of side-lobe rejec- project will be carried out in three stages, which in- tion and extremely low shape factor. Testing and refi- clude the formalization of the procedures, various nement of the stages of the production process of fil- types of tests, acquisition of equipment and mate- ters for the latest generation cell phone repeaters will rials and development of the manufacturing techno- be carried out. The following propositions will be logies on a large scale, among other activities. analyzed for use in this project: 1) new topology using sloping fingers to obtain desired response from the filter directly in the frequency domain; 2) new treatment of the reverse of the plate using grooves in Fiber Optic Sensor for saw-tooth configuration that guarantees the cancel- 274 the Petroleum Industry lation of volumetric waves in long band frequency; 3) new configuration of acoustic absorber to improve Coordinator: side-lobe rejection; and 4) analysis of the effects of Walter Américo Arellano Espinoza micro-soldering on the electrical behavior of the fil- Company: ters. Samples should be produced based on the tech- FiberWork Comunicações Ópticas Ltda. nologies developed and the results offered to poten- tial customers in Brazil and abroad. Approved value: Phase 1: R$ 8,400

Development of Protective This project aims to investigate the use of Fiber 273 Polymeric Electrically Highly Bragg Grating (FBG) technology to build Multi-pha- Conductive Films for Application se Flow Metering (MFM) systems for oil wells. Once on Electrochemical Energy the technical and economic viability are confirmed in Generating Devices and Manufacture phase 1, phase 2 should work towards the technologi- of an Automatic Applicator cal development of prototypes of FBG-MFM systems. The function of these systems is to discriminate and Coordinator: measure the fractions of volume in triphasic flows mi- Valdemar Stelita Ferreira xing petroleum, salt water and gas. In the future, or in

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case the development of FBG-MFM does not prove to Spectroscope be technically or economically viable, the project could 276 for Teaching be extended or redirected for FBG applications in other areas, such as: sensors for the aeronautical, na- Coordinator: val, civil engineering (dams and bridges) and medical Yoshikazo Ernesto Nagai industries. Applications of FBG in the area of tele- Company: communications – where this innovation finds the Optron Micromecânica Óptica Ltda.ME greatest variety of uses – could also be developed. Equally, the new professionals to be trained and the Approved value: infrastructure to be installed for the working of this Phase 1: R$ 15,500 project should find an almost endless range of gene- Phase 2: R$ 44,150 ration of inventions and technological innovations, all with high potential in terms of market and wealth Experiments which show atomic emission spec- creation. tra are an important part of a set which constitute the experimental foundations of Quantum Mechanics. These spectra are easily observed in a spectroscope, a Development and relatively simple instrument composed of a lamp 275 Nationalization of the made from the element, the spectrum of which you Technology for the wish to observe, and an optical collimator to collect Manufacture of Clonazepam the light from the lamp which passes through a nar- row slit, directed at an optical prism, the function of Coordinator: which is to spatially separate the various discrete lines William Carnicelli of different colors emitted by the lamp’s atoms. The- se colored lines are observed through a refracting Company: sight mounted on the moveable arm of a goniometer, Alpha Produtos Químicos Ltda. permitting the measurement of the deflection angle Approved value: for each line. The present project aims to manufactu- Phase 1: R$ 70,575 / US$ 70,575 re the complete spectroscope, a set of spectroscopic lamps (hydrogen, helium, argonium, mercury and The aim of the proposed project is the develop- sodium) and their electronic sources of activation, ment of technology for nationalization of the ma- the goniometer attached to the optical system for col- nufacture of Clonazepam, a product used in the lection, separation and analysis of light emitted, and pharmaceutical industry in the preparation of anti- the recording of the spectrum in various ways (vi- convulsive medicines consumed by patients who sual-manual, photographic and via microcomputer, have neurological problems, principally epilepsy. among others). The proposal in phase 2 involves re- The main manufacturer of these medicines is a searching and developing a hydrogen lamp with the multinational company which practically supplies aim of achieving a minimum half life of six months, the whole market with this specialty in Brazil. The bearing in mind the known difficulty of maintaining local manufacture of Clonazepam will enable it to its luminosity for any prolonged time. For the quan- be offered to national laboratories, in general large titative recording of the spectrum, a micromotor and manufacturers of generic medicines and the like, a light detector will be added to the spectroscope such as União Química, EMS, Sanval, Medley and built in phase 1 so that the luminous lines of the Teuto, among others. The product to be developed spectrum can be converted into electric signals capa- will meet the quality standards of Brazilian, Ameri- ble of being processed electronically. can, European and Japanese pharmacopoeia, allo- wing therefore for its export, principally to Merco- sul countries. In its first phase, the project will 14th BIDDING INSTRUCTIONS conduct a research and development study into the best route for synthesizing Clonazepam on a labora- tory scale, followed by its development on a scale of Development of Haploid-Inducing 20 liters. The next stage will be work on a 250 liter 277 Populations for Commercialization pilot plant, now in the pre-industrial phase. of Double-Haploid Strains of Maize

Coordinator: Fernando Fernandes de Andrade

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Company: spray of droplets torn from a curtain of water. Its in- Phoenix - Comércio, Importação novation consists in the geometry of the flows, with e Exportação de Sementes Ltda. a horizontal curtain of water perpendicular to the as- cending air discharge which creates an area of high Approved value: turbulence close to the wall. The smaller droplets Phase 1: R$ 47,100 / US$ 7,600 continue to ascend and evaporate, while the larger ones collect and drop down to the lower part of the Maternal haploids are obtained, in maize, when equipment, performing the washing and retention of haploid-inducing lines are used as a pollinator. The particles. The results of the humidification, of the haploids’ chromosomic duplication makes it possi- adiabatic cooling and the elimination of living orga- ble to reduce by two to three times the occurrence of nic material in the four prototypes tested in phase 1 homozygote strains, compared to the traditional of the project were clearly superior to those obtained method. Practical experience with the use of mater- from an imported air conditioner, recently launched nal double-haploids has indicated that the strains on the market. With the technical viability of the obtained in this manner display, on average, greater concept confirmed, it is believed that with develop- combination capacity than those obtained by self- ment in phase 2, the product performance should be fertilization. The main objective of this project is to even better. Market research confirms promising ex- introduce in Brazil populations of maize with ha- pectations for climatizers, as the appliances that carry ploid-inducing genes, developed and used commer- out adiabatic cooling and humidifying are generi- cially in Europe and the United States. These indu- cally being called. Applications range from air condi- cing populations will be evaluated as for their tioners for residential use, in clinics, industry, in adaptability for planting in the state of São Paulo, as shops and in churches, among many others. for the agronomic and phytosanitary characteristics, and as to their comparative efficiency in the gene- ration and identification of maternal haploids in tropical germplasma of hard and dentate grain. Optimization of the Process of Techniques recommended for the chromosomic du- 279 Organic Film Formation by Cataforetic plication of the maternal haploids will also be eva- Deposition, Aiming for Energy luated and a start made on intergression of haploid- Savings, Environmental Protection inducing genes in the company’s elite tropical and Adaptation of the Process strains. The project will constitute the basis of a to National Climatic Conditions program for the production of maize hybrids. The commercialization of strains will help national com- Coordinator: panies to compete in the oligopolized market, in- Célia Marina de Alvarenga Freire creasing the sector’s competitiveness. Company: Eccos Indústria Metalúrgica Ltda. Antibacterial Counter Approved value: 278 Flow Air Purifier and Humidifier Phase 1: R$ 73,000 for Domestic, Pneumological Clinics and other purposes Still a recent technology, painting by cathode pro- cess can still be improved. The development of this Coordinator: area is heading towards producing films aiming for Antonio Carlos de Barros Neiva products with reduced or non-existent lead levels, with lower cure temperatures and lower levels of pig- Company: mentation in the film applied. The process of pain- Aquar Desenvolvimento Tecnológico e ting by cathodic electro-deposition is mostly used in Comercialização de Climatizadores Ltda. trucks and vans, as with automobile chassises, since it Approved value: can be applied on a variety of substrates such as: Phase 1: R$ 24,200 cold-laminated steel, aluminum, galvanized iron and Phase 2: R$ 207,595 iron pre-coated with zinc alloys. The advantages of this process are greater anticorrosive power and less The equipment proposed in this project func- environmental pollution, among others. The objecti- tions as an antibacterial air purifier, humidifier and ve of this project is to implement the cataforetic cooler. It forces the passage of air through an aleatory painting process in an interested company, seeking to

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evaluate the existing commercial systems. It is inten- Development of the First ded to analyze the principal parameters of the pro- 281 Brazilian Analyzer for Combustion cess (deposition time, voltage and mode of voltage Gases and Environmental Emissions application and temperature), to obtain better per- formance in relation to energy savings, environmen- Coordinator: tal protection and resistance to corrosion. In the se- Ênio Carneiro de Medeiros cond phase, the focus will be on the influence of the Company: surface preparation to find alternatives principally Instrumeison Comércio de for the zinc and the zinc alloys, with a view to repla- Importação e Exportação Ltda. cing the chromatization processes with adherence la- yers for the electrodeposited paints. Approved value: Phase 1: R$ 74,593

Restoration of Value to Polyethylene/ The objective of this project is to develop the first 280 Aluminum Waste From Brazilian combustion gas analyzer to determine con- Cardboard Packaging of Long centrations of contaminants in the air. This equip- Life type, Post-consumption ment will make it possible to adjust to the maximum efficiency of industrial combustion processes (boi- Coordinator: lers, heaters and heat generation processes) thus re- Eliezer Gibertoni ducing the costs of electricity and fuels by means of adjustment in the burning systems. In addition, the Company: analyzer will be useful in the control of gas emission COPOL - Compostos Poliméricos Eliezer Gibertoni pollutants, reducing environmental effects which are Approved value: harmful to human beings and the environment, Phase 1: R$ 57,300 such as the formation of polluting smog, acid rain and the occurrence of allergic diseases. The follo- The objective of this project is to develop a con- wing steps are envisaged in the development of the tinuous process for the recovery of waste polyethyle- project: 1) Development of two different types of ne and aluminum derived from the recycling of electrochemical cells for the measurement of gases cardboard packaging of the long life type, which (O2 and CO); 2) Development of a gas probe, for consists of layers of paper, polyethylene and alumi- sampling, with integrated temperature measure- num. The recovery of post-consumption cardboard ment; 3) Development of a micro-controlled circuit packaging entails basically two different stages: the board for the digitalization of data, processing of removal and recovery of the paper in paper indus- signal and calculation of the efficiency of combus- tries and the regeneration and reuse of the polye- tion; and 4) Development of the plastic casing and thylene and aluminum in processes of plastics plastic accessory for conducting the gas into the transformation. This innovation is based on the de- electrochemical cells. For the second phase, the in- velopment of a disintegrator appliance, capable of tention is to make the product available to potential removing the residual cellulose fibers present in the business customers. plastic shreds. The contamination of the cellulose fi- bers interferes with the thermic stability of the poly- mer, preventing the use of the shreds in conventio- Use of Titanium nal recycling processes. The innovation proposed in 282 Powders Obtained the building of the disintegrator involves the design by the HDH Route of specific rotor systems to eliminate the residual cellulose fiber, together with systems of feeding and Coordinator: transporting the waste in an automatic and conti- Francisco Ambrózio Filho nuous manner, making it possible to obtain an in- Company: crease in processing capacity with guaranteed pro- Brats Indústria e Comércio Ltda. duct quality. The experiments carried out show that the material recycled in this way can be applied as Approved value: raw material in the manufacture of many products Phase 1: R$ 72,880 in the plastics transformation industry. Phase 2: R$ 298,000

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It has been established that, in the production of the fourth objective is to develop the audit of the titanium powder by the hydration/dehydration route company’s management process, allowing its matu- (HDH), there occurs a generation of a significant rity to be measured, as well as providing necessary quantity of fine powders that cannot be used for the information for the planning actions for the conti- manufacture of filters. This project seeks to identify nuous improvement of the management process at least two commercial products for the remaining and increase in productivity. The viability study of fractions of titanium powder. The proposed approach this project will include the topics of market re- is the use of the fine fraction of titanium powder for search, definition of the technical architecture of the the development of a production route for titanium product and development of the costs estimate and parts and direct use of the powder for spraying den- field research to determine the potential market seg- tal implants. The main result of the first phase of the ment for the product. project was the qualification by companies Prodoc- tor-Implac and De Bortolli, of pilot batches of tita- nium powder for spraying. Among the activities Research and Development planned for phase 2 are: the dissemination of the ap- 284 of a Process for the Synthesis of plication of titanium powders produced by the HDH Polypropylene with High Melt route for spraying bone-integrating dental implants; Resistance (HMS-PP) in Presence the production of pilot batches for parts; and making of Multifunctional Liquid Polymers viable the use of titanium powders produced by the HDH route for surface treatments (thermic asper- Coordinator: sion), among many others. If the proposed lines are Harumi Otaguro established, there will be an increase in foreign ex- Company: change earnings, by the simple fact of replacing an EMBRARAD - Company import with a material of increased value (titanium Brasileira de Radiações Ltda. powder) or a part manufactured from a sub-product (scrap or titanium residue) at lower cost. Approved value: Phase 2: R$ 181,277

Management of Companies Isotatic polypropylene (iPP) is one of the mate- 283 Based on Projects via Workflow rials with outstanding use in the polymer commodi- ties market owing to its special characteristics such as Coordinator: low density (a factor which accounts for its better Gustavo Holloway de Souza cost/benefit relationship) and, principally, low cost of production. Nevertheless, iPP displays a low melt Company: strength, which prevents it being used in various ap- Alexander Lucinski & Consultores plications in which elongational flow is dominant. Associados em Informática For example, applications of coverings extrusions, of Approved value: thermoforming free of residual tensions, of blowing Phase 1: R$ 59,500 of larger parts, as well as the production of low den- sity foams. With the aim of structurally modifying This project has four principal objectives. The iPP so it will display a high melt resistance, this pro- first is to develop a management workflow which di- ject proposes as methodology to irradiate, essentially rects the activities of the projects manager and takes with gamma radiation, pure iPP with additive in the into account the evolution of the company as this presence of multifunctional liquid polymers of the process matures. The second is the self-training of acrylate and methacrylate families. These monomers these managers to create a common culture and ena- will be responsible for the control of the ramification ble professionals of little experience to apply best or reticulation in the polymer. The choice of these practice in the management of projects. This objec- monomers is due to their solubility, high rate of reac- tive will be reached with the use of methodologies tion and availability on the market; the range of irra- and e-learning integrated into workflow processes. diation dose used will be around 10 to 20 kGy (kilo- The third objective is to introduce in the project the gray). The choice is due to the fact that these values development of various automated communication will have competitive prices on the Brazilian market functions, making it possible to increase the mana- and also because of the excellent results obtained ger’s efficiency and reduce errors in the project. And with the production of HMS-PP (high melt strength

• Translating Research into Business STERLILY MIGUEL BOYAYAN E SOHO (ESA & NASA) EDUARDO CESAR EDUARDO CESAR MIGUEL BOYAYAN MIGUEL BOYAYAN MIGUEL BOYAYAN 198

polypropylene) – an easier plastic product to produ- Company: ce and recycle – using acetylene gas as the multifunc- Orion Ind. e Com. de Sistemas tional agent. With this development, it is hoped to Automatos de Pressão Ltda. obtain a methodology or alternative process for the production of HMS-PP which will make it more via- Approved value: ble from the economic point of view and safer from Phase 1: R$ 39,130 / US$ 8,748 the occupational and environmental point of view. The project’s objective is to make viable the buil- ding of a prototype environmentally isolated pressu- Development of re sensor, using a low cost high quality stainless steel 285 Inorganic Low structure for use in the measurement of pressures in Toxicity Biocides gases, liquids and in media compatible with steel AISI 316. This entails a device with excellent stability Coordinator: and adequate longevity for industrial applications, Henrique Akira Ishii in automotive diagnostic systems, in hydraulics and other market segments which require high precision Company: and high performance. This type of apparatus incor- IPEL Itibanyl Produtos Especiais Ltda. porates the state of the art technology in environ- Approved value: mentally isolated pressure sensors and can be used Phase 1: R$ 74,246.33 for pressure transducers and transmitters. The pro- totype pressure sensor will contain: silica piezoresis- This project proposes the development of an tant microsensor; electrical terminals for contact; inorganic antimicrobial biocide, salts based on silver stainless steel casing; stainless steel membrane; ring with additions of zinc and/or copper nitrates, with a to secure membrane; vitreous resin for insulation of ceramic substrate (tricalcic phosphate, titanium dio- electrical terminals; and a piece made from ceramic xide and calcium silicate); its use covers the areas of for the electrical and thermal protection of the sen- treatment of drinking water, surgical-hospital mate- sor. The piezoresistant microsensors will be impor- rials (for example, catheters, dialysis tubes, floor and ted and lodged in a mechanical cavity made of stain- fabrics), cosmetics, paints and coverings, polymers less steel AISI-316, sealed by means of a corrugated and ceramics. Among the most attractive advantages membrane made from the same steel, the chamber of the use of inorganic biocides as concerns biologi- of which will be filled with a siliconated liquid, inert cal and environmental demands and antimicrobial to the sensor, which will transmit the pressure bet- activity, are the following: 1) low or non-existent to- ween the corrugated membrane and the piezoresis- xicity for human beings, hence, its use for application tant sensor. Thus, the microsensor will be conditio- in cosmetics and the treatment of drinking water; 2) ned by a medium inert to bad weathers and absence of risk to the environment; 3) it is not lea- aggressions that possible applications may present. ched (eliminated by being washed away or by rain, for example), which makes it ideal for application in fabrics, ceramics and paints; 4) long useful life. Inor- System for Generating Numerical ganic antimicrobials offer advantages in these areas 287 Terrain Models Based on when compared to traditional biocides (based on or- Polarimetric Images from Band P Radar ganic compounds) at a significantly lower cost. In ad- dition, this project should result in a technological Coordinator; gain for the country since it involves the develop- José Claudio Mura ment of a product without national equal. Company: Orbisat da Amazônia Ltda. Electromechanical Packaging of Approved value: 286 Environmentally Isolated Piezoresistant Phase 1: R$ 54,000 Pressure Sensors Used in Industrial Pressure Transducer and Transmitters This project aims to enable the company to gene- rate Numerical Terrain Models (NTM) by means of Coordinator: the use of polarimetric images from airborne Synthe- Humber Furlan tic Aperture Radar (SAR), in the microwave fre-

Translating Research into Business • 199 quency band named P band for environmental and Training System cartographical applications, among others. The me- 289 in the Area of Security thodology for the generation of NTMs is based on the use of interferometry of radar images, which uses Coordinator: the processes of image recording, calculation of pha- José Roberto Boffino de Almeida Monteiro se difference (interferogram) between images, phase Company: separation and calibration, geocodification and ge- Cientistas Associados, Comércio, neration of the NTM. P band was chosen because of Representação, Consultoria e Treinamento Ltda. the greater penetration of its microwave signal in areas with a dense forest covering. The penetration of Approved value: this signal is related to the forest structure and the Phase 1: R$ 75,545 polarization used. In the first phase of the project po- larization III will be used. The NTMs generated by the The training systems used today by security bu- proposed approach should represent the elevation of sinesses and by the civil and military police (state the terrain with low interference from the vegetation, and federal) do not permit much interactivity as according to the polarization used. The system they do not convey the sensation of reality with should be validated in areas of primary and secon- which the professional is going to be confronted. dary forestry physiognomy (height of vegetation and This project aims to remedy this deficiency with the biomass), in areas of homogeneous planted forest development of a computational system which per- (eucaliptus and pinus), and also in reservoir areas mits the user to interact with a reality much closer to with occurrence of aquatic plants (macrophytes). daily life. This system needs to employ advanced techniques in the area of interactive interfaces, pro- cessing and analysis of images and computational Microencapsulation of Pigments intelligence. The starting point is the showing of a 288 for Application in Special Paints film, as a foretaste, which depicts events such as as- saults, kidnappings, and bank robberies, among oth- Coordinator: ers, with real-size human beings. This will produce, José Leoni Tremeschin both through the images and the sounds, a sense of physical presence in the training environment. Carr- Company: ying a real weapon with silicon bullets, the user will Carol Química Ltda. have to take decisions, as for example the exact mo- Approved value: ment at which to draw the weapon and shoot and Phase 1: R$ 14,500 the point which the shot should hit. Subsequently, the film will be re-run taking account of the user’s The technique to be developed in this project decision. In addition, in a second stage, the system is should minimize or even eliminate some of the exis- intended to interact by shooting at the user, better ting problems in pigments used in paints. There will preparing him to face risks. be a chemical protection of the pigment with the coating of its particles, providing greater resistance to aggressive agents, such as ultraviolet rays, acidity and Development of Equipment alkalinity existing in the localities where the paint is 290 and Method for the Dehydration applied. It is also hoped that, with the encapsulation of Fruit and Vegetables of the pigment, it will present a minimum of aggre- gate and agglomerates, which permit economy and Coordinator: greater speed in the paint-making process. The en- Julio Suzuki capsulation could result in decreased absorption of Company: the pigments and represent a possible solution to the Fumito Comércio e Indústria Ltda. problem of stocking some paints which, with the passage of time, lose their drying power. This is be- Approved value: cause the pigments begin a process of absorbing the Phase 1: R$ 69,180 drying agents which disables, by means of chemical Phase 2: R$ 291,000 reactions with the vehicle, its characteristic of pro- moting the drying of the paint with a consequent loss Fruticulture has enormous potential in the Bra- of the product’s shine and finish. zilian agribusiness, but its expansion still needs to

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overcome hurdles such as the deficiency in post-har- sembly of a prototype covering basic communica- vest handling, principally to prevent the rotting tions functionalities. The objective of phase 2 will be which occurs during storage and transport. The the development of a 2.5/3G module for cellular main objective of this project is the development of communication with machines based on the chipset a machine for the dehydration of fruit and vegeta- chosen in phase 1. The commercial applications of bles aimed at carrying out the monitoring of the this product could include, among others: automatic principal variables in the process. The prototype will meter reading, such as water and electricity; vehicle be used to define the cycles of dehydration and the control (tracking and blocking); automation (in re- characterization of each type of fruit and vegetable, mote industries or production units); and electronic which will lead to the building of dehydration security in properties and ATM machines. equipment specific to the different products. There is no known dehydrator manufacturer in Brazil pro- ducing equipment which provides the technology Development of capable of processing different types of fruit and ve- 292 Optimization Solvers getables, offering a range of applications for a few ki- for Commercial Applications los (domestic machine), up to a hundred kilos (in- dustrial equipment). The basic working principle of Coordinator: the proposed dehydrator is the withdrawal of water Miguel Taube Netto by means of a drying action in which relative tempe- Company: rature and humidity are controlled so as to prevent Unisoma Matemática para Produtividade S/A. the deterioration process and minimize damage to the cell structure, preserving the integrity of the pro- Approved value: duct. In the second stage of the project the intention Phase 1: R$ 75,000 is to develop techniques and equipment for the Phase 2: R$ 200,000 / US$ 44,200 dehydration of vegetables. This project puts forward the proposal to valida- te and refine optimization solvers developed and Cellular Module 2.5/3G made available by national research institutions. In 291 for Machines this way, it is hoped that not only will UniSoma be able to end its present technological dependence on Coordinator: its international software suppliers, but also enable Lauro Rubens Lyra Girardelli the development of a policy to make better use of nationally developed technology. The project aims Company: to refine the Abate system, installed by UniSoma in KBS Empreendimentos e Participações S/C Ltda. the Perdigão company, to optimize the planning of Approved value: chicken slaughter batches, bearing in mind wider Phase 1: R$ 69,100 ranging applications, involving turkeys and pigs. This system should also be commercialized abroad. At the present time the route is being defined for Another goal of the project is to refine solutions al- the third generation of mobile phone (3G), which ready installed by UniSoma in the area of forestry will enable access to data at high velocity and will planning, used in Cenibra, Veracel and Aracruz, con- trigger the commercial explosion of cell phone tele- sidering heuristic methods in replacement for the metry applications. Some functionalities of the 3G CPLEX solver. Also envisaged is the development of cell phone are commercially available in the transi- a routing algorithm based on distribution centers tional technologies called 2.5G. The present project and deliveries with time window, taking as reference aims to prove the technical viability of the develop- the project under way with Casas Pernambucanas. ment of a modular 2.5/3G cell phone for communi- The company also aims, among other additional ob- cation with machines based on commercial chipsets. jectives, to broaden the non-linear programming In the first stage, the objective is the definition of the procedures available in Aimms (Advanced Integra- 2.5/3G chipset. The analysis is composed of: initial ted Multidimensional Modeling Software) for appli- specifications of the requirements, research on chip- cations in blending (mixtures) auto-oven load sets currently available, comparison (functionalities, (Companhia Siderúrgica de Tubarão) and petrol re- cost, reliability), choice of chipset to be used and as- fining (Refinaria de Manguinhos).

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Production of Linalool based on plications which demand high resistance to corro- 293 Essential Oil of Basil - a Sustainable sion, a characteristic obtained by the formation of a Ecological Alternative to Replace protective film of hydrated silica oxide on the surfa- Linalool from the Bendy Tree, ce of the component. This resistance improves when an Amazonian Threatened Species the silica content is increased. However, the mecha- nical properties are proportionally impaired by this Coordinator: increase. The low mechanical resistance of this ma- Nilson Borlina Maia terial, when compared for example, with common cast iron, is responsible for its limited use. To carry Company: out the first phase of this project an alloy based on Linax Comércio de Óleos Essenciais Ltda. the cast iron in question was selected, from which Approved value: three different metal alloys were produced – by the Phase 2: R$ 300,000 addition of new alloying elements in different per- centages –, with which the experiments will be car- This project aims to transform into production ried out. The base alloy will be composed of Carbon, the results of research developed in the Institute of Silica, Manganese, Phosphorus and Sulfur. In phase Agronomy, which showed the potential for the econo- 1 of the project, two alloys of different chemical mic exploitation of linalool derived from the essential compositions offered the best results for mechanical oil of basil. The development of this new system of resistance and toughness. These alloys will be cha- production is doubly advantageous. First, because it racterized by means of corrosion and wear tests at may free from extinction the bendy tree (physocolym- environmental temperature; bending, traction and ma scaberrimum), from which linalool has been tra- conventional impact tests at high temperature; and ditionally extracted. In second place, as it offers a real instrumented impact tests at environmental and opportunity for family farmers in the region of Votu- high temperature. poranga (SP) to make a living, creating a new segment in agribusiness: the exploitation of essential oils. Whereas the tree must wait more than three decades Production of MnZn Ferrites before its trunk can be cut down and the oil contained 295 with High Permeability and in it extracted, which signifies the elimination of the Low Magnetic Loss by plant, the leaves from the herb can be distilled to pro- Co-precipitation Method duce the essential oil three or four months after plan- ting, with the possibility of three crops per year. The Coordinator: research project concluded in the first stage clearly Suzilene Real Janasi showed the viability of the economic exploitation of Company: linalool derived from basil, given sufficient subsidies Imag Indústria e Comércio de to set up the industrialization of the product. Componentes Eletrônicos Ltda. Approved value: Development of Technology Phase 1: R$ 43,560 294 of Production and Phase 2: R$ 258,250 / US$ 10,595 Improvement to Mechanical Properties of High Silicate Cast Iron MnZn Ferrites (ceramic insulators with low den- sity of zinc manganese) are commercially obtained Coordinator: by the ceramic process which involves solid state Omar Maluf reactions between oxide precursors or carbonates at high temperatures (above 1100 degrees Celsius). The Company: resultant particles from this process are relatively lar- Fultec Inox Ltda. ge and not of uniform size, and the products obtai- Approved value: ned do not offer good reproducibility. Faced with Phase 1: R$ 45,656 these difficulties, the co-precipitation method looks Phase 2: R$ 91,304.40 like an interesting alternative. Using this method it is possible to achieve a more chemically homogeneous High silicate cast irons are basically ternary alloys powder, with finer, more uniform particles and good Fe-C-Si (iron-carbon-silica), recommended for ap- reproducibility. This project proposes the production

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of MnZn ferrites by the co-precipitation method, central aim of phase 2 will be to develop an integra- with the principal objective of obtaining a material ted and user-friendly system for the optimization of with high permeability and low magnetic loss for use insertions in the printed media based on the mean- in impedance nuclei, a product for which demand variance model. has been growing in the national market. The re- search will especially focus on the synthesis of the precursor powder and on processing. To make the 15th BIDDING INSTRUCTIONS production of these ferrites viable and to guarantee that the final product offers better properties than that produced by the ceramic method, all the condi- Optical Reflectometer tions of synthesis are being defined on laboratory (Not in Time-Domain) scale. Equal care will be taken in the processing of the 297 synthesized powder, principally where it concerns the sinterization cycle, an elaborate and important stage Coordinator: in the processing of MnZn ferrites, when properties Benjamin Grossman of high permeability and low losses are desired. Company: Cromática Sistemas de Comunicação de Dados e Informática Ltda. Optimizer for Insertion of 296 Adverts in Printed Media Approved value: Using Mean-Variance Model Phase 1: R$ 25,000 / US$ 6,500

Coordinator: Optical fiber joints display discontinuities in Pedro Jesus Fernandez connections involving optical connectors. The con- nection quality in monomode fibers is characterized Company: by various losses of a physical order, such as inser- Ipsos Novaction Brasil Ltda. tion loss, return loss (or reflection loss), of a geome- Approved value: tric order such as dislocation of the apex, measure- Phase 1: R$ 73,680 ment of protrusion or inversely, measurement of Phase 2: R$ 217,000 fiber recession in relation to the end of the connec- tor, and alteration of polarization in polarization-re- The objective of this project is the development taining fibers, among others. This project proposes of an optimization system for printed media based the construction of a reflection-loss meter, known as on the model of generalized mean-variance (known an optical reflectometer (not in time-domain) to be also as the generalized Markowitz Model), a celebra- used to measure the optical power that returns ted paradigm in the financial market, but as yet not through the fiber in the mentioned discontinuity. In exploited in the media market. A mean-variance high velocity optical joints and also in those that use model manifest itself in the form of a problem of multiplex or wave complement, the return loss is a quadratic programming in which the function-ob- fundamental variable to be measured. At present, te- jective represents a compromise between the expec- lecommunications operators routinely insist that ted return (profitability) and variance of return this variable be measured within a certain range for (risk). In this approach the diversification of steps each connector to be accepted and included in the occurs naturally, without the need for artificial res- network, besides of course, the other variables men- trictions. Linear restrictions, such as disposable bud- tioned which must also fit within acceptable ranges. get, can also be inserted in the model. In phase 1 of this project, the proposed methodology was imple- mented in a prototype validated by means of real Development and data on the sales of magazines. Two fundamental 298 Optimization of a Process characteristics of the model were verified. In the first for the Electrosynthesis place, it allows linear restrictions to be imposed and of Hydrogen Peroxide dealt with, which lends the model great flexibility. In the second place, it demonstrates its ability to speed Coordinator: up the process of creating efficient media plans. The Carla Badellino

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Company: genic nematodes. In view of the results obtained in Água Limpa - Bertazzoli Ltda. the project “Entomopathogenic nematodes: mass production and potential for use in the control of Approved value: pests”, financed by FAPESP and coordinated by the Phase 1: R$ 44,866 Biological Institute, the intention is to commence in- Phase 2: R$ 162,119 dustrial production of these organisms (Heterorhab- ditis sp. and Steinemema sp.), with a view to commer- Hydrogen peroxide, an oxidizing agent used in cializing them for use in the control of various insects organic syntheses, discoloration processes and blea- and pests. The objectives of the present project are: 1) ching and in the treatment of effluents, can be gene- to compare the yield of Heterorhabditis sp. and Stei- rated by the reduction of oxygen in watery solutions. nemema sp. produced by the sponge and fermenta- In this project, the objective is to develop and make tion processes; 2) to develop and evaluate formula- commercial and process an item of equipment for tions of entomopathogenic nematodes; 3) to produce the electrosynthesis of hydrogen peroxide for use in the nematodes on a semi-industrial scale; 4) to con- the oxidization of organic compounds and in the firm the efficiency of the nematodes produced in vi- treatment of industrial effluents. In phase 1 of the tro against some insect pests; and 5) study the market project a study was carried out into the viability of for the use of entomopathogenic nematodes. In the the proposal by means of benchtop trials. Phase 2 studies undertaken in the first phase of this project, will involve the assembly of a prototype of electro- the real and the potential markets for the use of the- chemical reactor. The intention is to structure the se nematodes were evaluated as well as the difficulties design, the manufacture, assembly, installation and and the requirements to establish in the second pha- begin to operate the equipment for the production of se, a biofactory for these agents, with a large part of hydrogen peroxide. Subsequently, studies will be car- the problems associated with mass production now ried out to optimize the functionality with regard to solved. The establishment of a biofactory for ento- the speed of electrogeneration and the electric effi- mopathogenic nematodes will be of great importan- ciency. Intensive operation will also serve to establish ce for the advance in the handling of pests in Brazil, operating routines, the useful life of the components, with the reduction in the use of chemical insecticides the periodicity of preventative maintenance and the and all the other resultant advantages. operation and maintenance costs. The intensive ope- ration tests will include the electrogeneration of the oxidizing compound in the in situ treatment of simu- lated watery effluents. For these tests effluents contai- Development of a ning the reactive colorant Remazol Black and also the 300 Controller for Application acidic herbicide, 2,4-Dichlorophenoxyacetic acid of Liquid Fertilizers (2,4-D) will be used. Coordinator: Claudio Kiyoshi Umezu Evaluation of Methodology and Company: 299 Techniques for the Industrial Tandra Sistemas de Controle Ltda. Production of Entomopathogenic nematodes and Study of Market for Approved value: Commercialization of these Agents Phase 1: R$ 45,060

Coordinator: The application of agricultural fertilizers has tra- Carmen Maria Ambros Ginarte ditionally used fertilizers of the solid, pre-formula- ted types. However, higher levels of productivity Company: have been obtained with the adoption of liquid fer- Bio Controle - Métodos tilizer, which offers a further advantage: the possibi- de Controle de Pragas Ltda. lity of greater control over the quantity and the area Approved value: where it is used, decreasing losses and contamina- Phase 1: R$ 55,201 tion of the environment. The equipment for the ap- Phase 2: R$ 282,617 plication of liquid supplies existing on the market, controlled by electronic devices, can operate cons- Despite the large existing market, there is still no tant or variable application rates, however they are company in Latin America producing entomopatho- not able to formulate the supply according to the lo-

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calized need of the soil nutrients. The principal ob- the method of image analysis is based on a techni- jectives of this project are: 1) to study the technical que of precise segmentation of the spots; the data- viability of an autonomous control system for the bases can store families of experiments and not just local application of liquid fertilizer at variable rates, one experiment, as is the norm; the procedures of with the capacity to vary the formulation in real reduction of dimensionality applied are innovate time, which may be used in commercial implements techniques developed by the group itself. already existing; and 2) to carry out the preliminary analysis of the cost of the control system and its commercial return. The evaluation of the control Modeling and Development of a system will be undertaken in the laboratory, using 302 System for Integrated and Efficient application maps specially created with a view to ex- Management of Electricity Sector ploring different work situations as far as formula- tion and dosage are concerned. In this stage a cost Coordinator: analysis will also be undertaken and the identifica- Elias Roma Neto tion of suppliers. Company: Mind Games Software S/C Ltda. Development of Modular Approved value: 301 Software for the Analysis Phase 1: R$ 19,982 of Genic Expression The present electrical energy crisis is leading go- Coordinator: vernments, businesses in the electricity sector and Daniel de Oliveira Dantas large consumers to look for new ways of generating, transmitting and distributing energy and solutions Company: for increasing efficiency and installed capacity. Bra- Sunset Informática Ltda. zil has gone on to discuss in greater depth the qua- Approved value: lity of the energy generated, transmitted, distributed Phase 1: R$ 55,900 and consumed in a scenario of a restructured electri- cal sector. The basic objective of this study is to test This project aims to develop a piece of modular the technical viability of the development of a com- software for the analysis of genic expression, measu- putational tool the conception of which is geared to- red by microarrays, membrane arrays, sage or other wards helping the management of the electricity sec- techniques. The software should be composed of tor in an integrated and efficient manner. Its specific the following modules: image analysis; database; objectives are compliance with legal obligations on normalization; clustering, and reduction of dimen- the part of the agents, including the regulatory bo- sionality. The image analysis module permits the dies, preservation of natural resources afforded by measurement of expression based on microarray the promotion of information, and simulations and images or membrane array. The database module improvement in the quality of services and manage- stores the architecture of the analyzed chip, the ge- ment support based on the integration of diverse nes associated with each spot and permits the orga- sources of information handled under the focus of nization and retrieval of information from several process and information technology. It is hoped that related experiments. As the name itself indicates, the specification of this computational tool will as- the normalization module attributes measurements sist in the simulation of desired results and the iden- for various experiments with the same reference, tification of the origin of distortions and waste, with making it possible in this way to compare results. a view to reducing costs and an improvement in the The clustering module makes possible the grouping quality of the services delivered. of similar signals, obtained in experiments of tem- poral expression measurement or progressive, in- creasing or decreasing stress. The reduction of di- Production of mensionality permits the discovery of a minimum 303 Colored Gold Alloys gene set, the signal of which makes it possible to dif- by High Energy Milling ferentiate at least two biological states of interest. This software offers some innovative characteristics Coordinator: compared to other known programs, among which: Eneida da Graça Guilherme

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Company: have an impact on the international market. The ba- Regulus Ars Tecnologia em Jóias Ltda. sic proposal is to assemble an atomic absorption spectrometer with an electrothermic atomizer, using Approved value: a complete tungsten filament, including: light sour- Phase 1: R$ 70,600 ce with a mechanically choppered hollow cathode lamp, high resolution monochromator with wave- The fascination which gold exerts through its length around 1,0 nanometer, detection system with brilliance, beauty and rarity is the great driving force lock-in amplifier and photomultiplier, analogue-di- in jewelry technology. In this context, color plays an gital converter, software for management of system important role, since it adds diversity and originality and mathematical treatment of signal. To test the to the pieces, adding artistically to their value. Based initial technical viability, the prototype will be sim- on a technique used in powder metallurgy, known as plified with a hollow cathode lamp. With good re- high energy milling, this project aims to create, me- sults obtained in the first phase of the project, in the chanically, colored (white, red, green, violet, blue and second phase this prototype will be perfected, inclu- black gold alloys). The production of powdered colo- ding automatic lamp change, automation of prepa- red gold is unprecedented in Brazil and in the world. ration and introduction of samples. Once the pro- The powders of the alloys obtained will be aimed at duct is developed, the intention is to launch it decorative coverings, especially in the case of jewels, initially on the Brazilian market, and subsequently giving them an innovative artistic cachet. The pro- offer it on the international market. duction of the alloy powders by milling (processing in solid state) will allow the chemical composition of the product to be controlled with great precision, which will afford a sensitive adjustment to the colors. T-Learning – The form of the powders will also be able to be con- 305 Learning Based on trolled, which will have a direct bearing on the bril- Interactive Digital TV liance of the product. The technological innovation proposed here will be employed in Regulus Engenha- Coordinator: ria, counting on the partnership of a jewelry designer Rodrigo Cascão Araújo and with the support of laboratories of the Institute Company: for Energy and Nuclear Research, Ipen. Amaury José Alves Aranha Approved value: Development of Atomic Absorption Phase 1: R$ 26,360 304 Spectrometer with Electrothermic Phase 2: R$ 232,460 Atomization Using Tungsten Filament Based in Pulsed Xenon This research aims to approach the state of the Lamp and Linear Image Sensor art in T-learning, with a view to developing colla- borative training and learning programs, using the Coordinator: technology of digital television transmission. In pha- Lídio Kazuo Takayama se 1 of the project, the studies carried out delved into themes linked to the technologies involved in the Company: transmission and production of programs for digital Femto Indústria e Comércio de Instrumentos Ltda. TV. In parallel, a detailed analysis was undertaken of Approved value: the way of adapting the teaching methods of existing Phase 1: R$ 74,255 training courses for online learning to a model based Phase 2: R$ 300,000 on transmission and interactivity via digital TV. In the first phase of the project some prototypes of At the present time there is no manufacturer educational programs were developed, aiming to re- producing atomic absorption spectrometers in Bra- fine the existing technologies. At the same time, pu- zil. The aim of this project is to develop and launch blic and private learning institutions were identified the first of these devices with totally Brazilian tech- which had an interest in participating as partners in nology and software, in the hope also that it will the development and as users of the programs to be

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created. In phase 2 of the project, the intention is to Software Dental Software for Color draw up a business model involving the supply of 307 Mapping and Selection of Restorative software components, audiovisual products, interac- Materials Aided by Computer - Phase 1: tive services and learning objects for digital TV. The Determination of Colorimetric development of this model should involve the re- Variation Curve of Resin Compounds search and generation of innovative technological products and the search for partners and customers Coordinator: to broaden the application of the results of the pro- Osmir Batista de Oliveira Junior ject. Company: Fornazari, Papini & Cia Ltda. Production of Approved value: 306 Stainless Steel Powder Phase 1: R$ 36,312 by Water Atomization Errors in the empirical selection of colors of es- Coordinator: thetic restoration materials are fairly common in Nelson Karsokas Filho dentistry and cause financial and psychological dis- tress to patients, as well as giving rise to doubts con- Company: cerning the competence of the dental surgeon. The Brats Indústria e Comércio Ltda. objective of this software is to develop a piece of na- Approved value: tional software to map tooth color and indicate Phase 1: R$ 67,000 which restoration materials should be used for the esthetic solution of clinical cases. This software This proposal aims to develop and qualify a should have advantages such as low cost, guarantee producer of austenitic stainless steel powder by wa- of reliable results, greater productivity and lower le- ter atomization, with a monthly supply capacity of vel of stress, both for the patient and for the profes- 20 kilograms of powder within granulometric ran- sional. For the preliminary testing of the viability of ge of between 500 and 850 micrometers and with this proposal, part of the module recognizing the apparent density below 2 grams per cubic centime- standards will be developed, with the aim of acqui- ter, specified for use, principally in the manufactu- ring the specific knowledge for finalizing the softwa- re of porous components. The basic objective of re. The company will use the concepts of fuzzy logic, the project are: 1) Identification of the effect of proposed by Zadeh (1960) to determine the varia- process variables (type of raw material, nozzle dia- tion in colorimetric curve of test samples of resins meter, water pressure and flow temperature) in the composed of different manufactures and colors. characteristics of the powders obtained; 2) Produc- This sub-model will read pixel by pixel all the ima- tion of pilot 20-kilos batches, per month; and 3) ges from the test samples and will determine the in- Manufacture and characterization of metallic fil- terval limit (maximum and minimum) for each ma- ters produced from the pilot batches. For the first terial tested and will characterize each resin in terms phase it is hoped to define the atomization process of the greater frequency of pigments present in each parameters that will permit the production of at of the test samples. The images will be analyzed wi- least 20 kilograms with a granulometric range bet- thout conversion to determine the shade/color ween 500 and 800 micrometers and an apparent depth and in grayscale to determine the luminosity density below 2 grams per cubic centimeter. As curve of each one. yield in this range is probably low – close to 25 per cent – a hoped for result is the viability of using the fine fraction, principally for the manufacture of Hotel Environmental sinterized structural components, either by con- 308 Adaptation Project – Diagnosis, ventional powder metallurgy, or by powder injec- Adaptation and Environmental tion molding. The intention is also to build pro- Innovation in Hotelier Sector totypes to be tested by end-users for performance evaluation, comparing them with parts obtained Coordinator: from imported raw material. Takako Matsumura Tundisi

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Company: forestry businesses, associations and public institu- Instituto Internacional tions linked to the sector. This entails a management de Ecologia São Carlos Ltda. tool which evaluates the forest conditions, the return on forestry products and management activities and Approved value: their impact. The project also includes a manual, Phase 1: R$ 51,266 training and software installation services. The sys- Phase 2: R$ 224,911 tem should organize and store on a relational data- base all the monitoring information and make it The central region of the state of São Paulo, com- available to the user for the tracking of performance prising cities such as Águas de São Pedro, Barra Bo- indicators, by means of practical methods of calcu- nita, Bocaina, Brotas, Corumbataí, Descalvado, Dois lation and data analysis. In addition to this, Monitor Córregos, Dourado, Ibitinga, Pirassununga, Porto will provide with great facility the information re- Ferreira, Ribeirão Bonito, São Carlos and São Pedro, quired for certification processes, audits, licenses, among others, has proved to be one of the major po- evaluations of environmental impact and control, les of tourist visitation in the state. This project aims among others. The system should help companies to develop and apply a methodology for diagnosing justify investments in the adoption of alternative the environmental adequacy of the hotelier busines- production practices and in the restoration of degra- ses located in those cities, with the creation of a di- ded resources. The development of the software will gital database to process the information qualitati- be based on the diagnoses which were carried out by vely and quantitatively. It is also intended to format two forestry companies, Precious Wood and Riocell digitalized maps of the region so that the businesses (Aracruz). In this way, Monitor will address both can visualize their location in the light of thematic Brazilian forestry realities, namely, natural forests maps of hydrography, road network and vegetation, and planted forests. aiming for greater use in terms of typology/locality of the exploited resources. A piece of software will also be developed, applicable to any other region in the country containing the methodology for self- 16th BIDDING INSTRUCTIONS diagnosis and road map for the implementation of necessary environmental adaptations which could be acquired by any interested public or private sec- An Approach to tor. Guidance will be available regarding any resul- 310 Gradual Migration from tant regional adaptations, in terms of the dimen- Legacy Applications sions of the task, the proximity and sustainable forms of exploitation of the natural resources, as Coordinator: well as the breadth of the adaptation, whether com- André Luis Costa de Oliveira plete or in sectors. Company: Apyon Technology S/A Monitor: an Environmental, Approved value: 309 Socioeconomic, Operational Phase 1: R$ 61,650 and Production Monitoring System An Approach to Gradual Migration from a Le- Coordinator: gacy Applications Software System is an evolutive ar- Tatiana Mahalem do Amaral tifact. With the passage of time, its original design and implementation are modified to meet new re- Company: quirements and/or to improve its performance, in- Athena Sistemas de Gestão corporating substantial new knowledge into its con- em Recursos Naturais Ltda. text. This process is called constant maintenance. Approved value: But after four years, approximately, applications be- Phase 1: R$ 54,500 come legacy, since the technology on which they Phase 2: R$ 89,300 / US$ 1,787.50 were based are out-of-date and in the majority of ca- ses no longer supported by the manufacturers. Le- The project will bring about the development of gacy applications contain program logics, project an environmental, socioeconomic, operational and decisions, users’s requirements and business rules production monitoring system (Monitor), aimed at that need to be recovered, interpreted and converted,

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which corresponds to approximately 25 per cent of and methodologies in project management. By using the application’s complexity. The remaining 75 per it, a technical memory of projects is created which cent is related to technological aspects, such as tran- serves as a base for the management of knowledge in sactions, connections, databases, components and the organization. With a structured workflow in graphic interfaces. One of the forms currently used which the system requests approval of the informa- for the reconstruction of pieces of software is total tion sent out by the manager, the system integrates and direct migration from the legacy application. those at higher levels in an organization who need to This type of migration demands a great deal from receive project information. In addition to the priva- the software engineers, who need to have as much te sector, this product is also aimed at public agen- knowledge of the technology used in the legacy ap- cies, such as secretaries of state and municipalities. plication as that used in the new application. Fur- The commercial impact of this product is high, thermore, legacy applications generally don’t possess owing to the growing need for project management documentation. An alternative for the reduction in support tools and the lack, at the present time, of in- time and complexity in the migration from legacy tegrated solutions for the tracking of a portfolio of applications would be the identification and separa- strategic projects. In the area in which some public tion of rules that govern business and technology. organizations operate, its application is of funda- This separation would permit the gradual migration mental importance to increase efficiency and trans- from the legacy application and coexistence between parency in the management of resources. the legacy application and part of the reconstructed application, lending flexibility to the migration. Therefore, the objective of this project is to make Technological Development migration from legacy applications viable and secu- 312 Platform for Precision re for businesses. What is proposed is an approach to Irrigation of Perennial Crops gradual migration, guiding the software engineer in the reconstruction of that application and integra- Coordinator: ting tools and new techniques such as, for example, André Torre Neto Refactoring, Web Services and EAI. Company: Enalta Inovações Tecnológicas para Agricultura SGEP - System for the Strategic Approved value: 311 Management of Projects; Computerized Phase 1: R$ 61,060 System for the Tracking and Management of Projects, Around 70 per cent of potable water on the pla- Geared Towards Decision Makers net is used in agriculture. Charging for the supply of water resources in rural areas, which has been adop- Coordinator: ted to combat waste and promote the rational use of Daniel Estima de Carvalho water brings with it, however, negative consequences for agribusiness. This situation shows that it is vital Company: to develop technologies for the rationalization of Easylearn S/C Ltda. water use in irrigated systems, making production Approved value: possible, without nevertheless causing negative im- Phase 1: R$ 30,899.99 pacts in society. This project aims to develop an au- tomatic system for precision (spatially differentia- The System for the Strategic Management of ted) fertirrigation in perennial crops, under Projects (SGEP) aims to supply critical information irrigation by micro-watering or drip irrigation. The on projects to its users. The system centers on the system will have sensor devices and intelligent acti- project manager, who will be the main source of in- vators linked by a wireless network. Based on this formation, but it focuses on the tracking that must network, a piece of software will be produced to be done by directors or coordinators, providing a handle the differentiated application of water and broad vision and enabling greater control over pro- fertilizers, which should monitor biotic and abiotic jects of a strategic nature. The idea is that the system parameters in the production system, allied to con- tracks, in a synthetic manner and with focus on ex- ventional and non-conventional information and ceptions, the entire life-cycle of a project. Once ins- methodological technologies for the space-time talled, it allows for a standardization of procedures analysis of data. The system will be developed ini-

Translating Research into Business • 209 tially for citriculture, owing to its economic impor- Company: tance in the state of São Paulo, because of the logis- BCB Comércio de Sucatas Plásticas Ltda. tics made available and pressing need in the face of Approved value: the sudden death of citrics. However, being versatile Phase 1: R$ 19,871 and capable of being implemented in stages, it will be easy to adapt it to other perennial crops, such as This project aims to develop and evaluate the fruit and coffee growing in general. technical viability of blends of recycled PET – (PETr) – and polycarbonate (PC), using chemical compati- bilization in a continuous extrusion process. The Development of a Computational objective for obtaining these blends is to take advan- Tool for the Design and Analysis 313 tage of the individual characteristics of their compo- of Networks of Optical Packets nents in a single material. In PC, the characteristics would be resistance to impact and good temperature Coordinator: performance and, in PET, stiffness and chemical Antonio Marcos Alberti resistance. Since PET is a post-consumption materi- Company: al and recycled from carbonated drinks packaging, it Ignis Comunicações S/C Ltda. would be characterized as technological innovation, Approved value: which would result in an excellent cost-benefit rela- Phase 1: R$ 63,044.20 tionship for the product. The material to be devel- oped could be used in engineering, in direct replace- To make use of the entire transmission band ment for other thermoplastics and other blends such which optical networks based on WDM (Wave- as polyamide (nylon), ABS, ABS/PC, PBT/PC and length Division Multiplexing ) technology permit, others, in injection processes in technical parts in the different technologies have been and are being deve- automobile industries, in hermetic compressors, in loped such as: broadcast-and-select, routing, Optical household appliances and electroelectronics. In pre- Packet Switching and Optical Burst Switching. Stu- liminary contacts with the automobile industry, the dies on networks based on optical packets began at need to use quality recycled materials in their prod- the end of the 1990s. It involves a new and promising ucts was emphasized. As yet there is no national sup- technology which seems likely to revolutionize opti- plier meeting the technical requirements of the cal systems even further. In the belief that the deve- material at a suitable cost. lopment of new devices and systems based on these innovations will create a demand for computational tools for these networks, as happened with WDM, Integrated Robotic IgnisCom is proposing the development of a com- 315 System for the Areas mercial tool for the design and planning of optical of Education, Research packet networks. The objective is to offer an unpre- and Entertainment cedented product, which will be launched on the market before others that include this technology. Coordinator: Besides the innovative technology in the modeling Claudio Adriano Policastro and analysis of optical packet networks, the propo- Company: sed tool will also have some innovations in its archi- Cientistas Assoc. Comércio, Representação, tecture, amongst which we can highlight: Simulation Consultoria e Treinamento Ltda. Integrated with Planning, Dynamic Project Mana- ger, Optimization of Parameters Link and Expanda- Approved value: ble and Modular Library of Models. Phase 1: R$ 74,908.74 Phase 2: R$ 318,859.65 / US$ 4,206.15

Development and The objective of the system is to offer an integra- 314 Characterization of Blends of ted environment with mobile robots and support Ethylene Polyterephtalate software for the programming and development of Recycled/Polycarbonate (PETr/PC) teaching activities to act in three specific areas: edu- cation, research and entertainment. This project Coordinator: proposes the development, the application and the Arioaldo Peronti Barboza transfer of technology from three sub-areas of infor-

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mation technology: Robotic Intelligence (RI), Artifi- dent cathodes; 2) to offer metals surface nitriding cial Vision (AV) and Automatic Speech Processing service using a clean and modern technology and a (ASP). These areas offer a high degree of originality controlled and reproducible process; 3) manufacture and relevance for the scientific and industrial envi- and commercialize complete plasma nitriding plants. ronment in relation to man-machine communica- tion through voice and artificial vision. The impor- tance of this project derives from the application of High Precision Intelligent innovative technologies in RI, AV and ASP,to produ- 317 Piezoresistant Pressure Transmitters ce a national software and hardware kit applied to for Aggressive and educational and entertainment robotics. In phase 1 Non-Aggressive Environments of the work a main module with a robot base, a pro- totype of the Vision Module, a Radio-Modem Mo- Coordinator: dule and an Integrated Robot Programming and Edgar Charry Rodriguez Control Environment were successfully developed. Company: In phase 2 it is intended to take forward the develop- Mems Microsystems Integrados Híbridos de ment of the modules planned for this stage: Interac- Pressão, Indústria e Comércio Ltda. tive Module, Image Processing Module, Infrared Vi- sion Module, Grip Module and Voice Module. Approved value: Phase 1: R$ 61,692.12

Construction of a Metals The aim of this project is to build a prototype in- 316 Nitriding Plant Using a New telligent piezoresistant pressure transmitter which am- Technology of Pulsed Plasma plifies the pressure sensor signal and is adapted using programmable amplifiers and 16-bit CPU on a single Coordinator: chip. In this method, the pressure and temperature Daniel Wisnivesky signals are treated and presented as input in the pro- grammable amplifier, effecting the amplification, cali- Company: bration, linearization and temperature compensation Industrial Heating Equipamentos of the sensor signal. This transmitter can be exposed to e Componentes Ltda. aggressive and non-aggressive environments, being Approved value: used in the measurement of gases and liquids compa- Phase 2: R$ 276,400 tible with AISI-316 steel at different temperature ran- ges and working pressures. The equipment is suitable The plasma nitriding of metals is a thermochem- for industrial applications, automotive diagnostic sys- ical process which allows the properties of surface tems, hydraulics and other segments of the market hardness to be altered, improving the resistance to that require high precision, high performance and ex- wear, to corrosion and the material’s thermic resis- cellent quality. The transmitter prototype should have: tance. The process is used in the treatment of ferrous process connection nipple; environmentally-isolated metals, refractory metals and, more recently, alu- piezoresistant pressure sensor; printed circuit board minum. The nitriding of surfaces is used, among with signal conditioning chip; discrete components; others, in the mechanical, automotive, hydraulic, tubiform steel casing; and electric connection. metallurgical, biomedical and food industries. The process is used in the treatment of plastics injection molds for automotive parts (valves, gears and pis- Development of tons ), aluminum extrusion dies, tools for cutting 318 Alumina-Based and machining metals, perforations for casting Cutting Tools molds in general and in the treatment of prostheses, among others. This project proposes the building Coordinator: and exploitation of a plasma nitriding plant, of Edval Gonçalves de Araújo medium size, using the concept of a furnace with Company: multiple independent cathodes with the following Macea Cerâmica Técnica Ltda. objectives: 1) innovate in the functioning of the pulsed plasma nitriding furnace by using the tech- Approved value: nology of modular furnace with multiple indepen- Phase 1: R$ 49,900 / US$ 6,000

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Currently, alumina-based cutting tools are not technic School (LSI-EPUSP). The kit should compri- produced in Brazil. Their main application is in the se a complete set of building blocks consisting of machining of tempered steels and cast irons, mate- printed circuit boards, electroelectronics components rials widely used in the metal-mechanics industry. and the respective support material, which will allow With this project, it is intended to transfer to Macea for multiple combinations. The blocks will be divided Cerâmica the fine ceramic technology developed in in three types: entry, processing and exit, each one the Ceramics Department of the Institute for Energy containing corresponding elements and effective and Nuclear Research (Ipen), for the company to functioning, regardless of whether or not there is a manufacture and commercialize the inserts. The computer. Given the lack of attractive learning tools market for alumina inserts is in full expansion in and materials in this educational sector, the project Brazil, because the modernization of the country’s could fulfill an important function as a demystifier of industrial base presupposes the purchase of high- technologies that nowadays are seen as black boxes. performance machinery and, consequently, with The implementation and testing of a prototype of the high cutting speeds, in which ceramic pellets have kit should serve as a basis for the manufacture and their application. In the use of cutting tools for cast commercialization on a product scale. iron and tempered steels, it is necessary to increase the hardness of the alumina with the addition of ti- tanium or niobium carbide, to condition the powder Development of by grinding and/or to use the spray dryer technique, 320 PET-recycled/ABS Blend followed by hot-pressing of the powder. The sinteri- zation should be carried out in an argonium atmos- Coordinator: phere in temperatures of the order of 1700°C for pe- Irineu Bueno Barbosa Junior riods under 60 minutes. The final stage is the Company: correction/polishing of the pieces. The proposal of BCB Comércio de Sucatas Plásticas Ltda. this first stage of the project is to define the compo- sitions and the process to produce inserts from alu- Approved value: mina-based compounds with a geometry widely Phase 1: R$ 18,296 sought after in the industry and test those parts di- Phase 2: R$ 400,000 rectly in companies. The environmental problems caused by the incor- rect disposal of polyethylene-terephthalate (PET), can Project be minimized by recycling, which avoids the accumu- 319 Workshop Kit lation on rubbish dumps and reduces the consump- tion of petroleum. Depending on the technology in- Coordinator: volved in the recycling process, it may be possible to Irene Karaguilla Ficheman take advantage of the excellent properties of this ther- moplastic (recycled PET) in quality applications such Company: as engineering, adding a significant value to it. For Criartec Indústria, Comércio e this type of use, it is necessary that the thermoplastic Serviços de Materiais Didáticos. demonstrates a good relationship between the pro- Approved value; perties of hardness and resistance to impact. Phase 1 Phase 1: R$ 46,969 of this project evaluated the technical viability of blends of recycled PET and Acrylonitrile Butadiene Estirene (ABS), aiming for its use in replacement for The main objective of the Project Workshop Kit is different engineering thermoplastics. The results sho- to research and develop products aimed at guided wed that the blends developed have an excellent cost- learning through the solving of problems by means of performance relationship, with great potential for re- carrying out projects. This proposal will serve as a placing different engineering thermoplastics in tool in the area of technology education for children injection processes of technical components, in sec- and adolescents, in the formal sphere (primary and tors such as the automobile, electroelectronics, house- secondary), in the non-formal sphere and in home hold appliances and telecommunications sectors. use. The project will be developed through a partners- With its commercial viability proven, the objective of hip between Criartec and the Laboratory for Integra- phase 2 of the project is the study of the behavior and table Systems of the University of São Paulo’s Poly- adaptability of the new materials to the production

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processes of future customers, undertaking try-outs Company: of injection of technical components with pilot bat- Ótica Online Ltda. ches with additives. It is also intended to carry out tri- Approved value: als and performance tests on injected components. Phase 1: R$ 21,050 Phase 2: R$ 310,003.75 Improvement to the Quality of The aim of this project is to develop and build an Recognition and Availability 321 automatic, self-service, intelligent kiosk for the (SpeedCluster) of Griaule’s AFIS adaptation, testing and commercialization of specta- cles. This solution is the result of the company’s Coordinator: experience in the sale of spectacles via the internet, Iron Calil Daher in which problems of credibility in the process were Company: noted, due to the lack of physical presence and mea- Griaule Technology Ltda. suring instruments and calibration of the patient’s optical data. The development of this kiosk should Approved value: also offer a virtual on-line trial of the available frame Phase 2: R$ 296,000 models. The Digitok authoring system for self-ser- vice solutions will be used to create products in three Griaule developed and commercialized a Brazi- modules. These modules provide the main function- lian system for the identification of fingerprints (Au- alities for the building of self-service applications, tomated Fingerprint Identification System, AFIS). from access to the database up to the remote man- The software is in use in the states of São Paulo, Rio agement and monitoring of procedures. The tech- Grande do Norte, Sergipe and Tocantins. Tests con- nologies used in the development, both the author- ducted internally, based on the procedures of the ing systems and the resultant applications, aim for University of Bologna (Unibo), demonstrate that, the perfect integration of different environments, out of 28 international competitors, the product lies using standardized tools and components. The in tenth position. The first objective of this project installation of the kiosk will use interactive forms of presented here is to improve the system’s recognition software, which will be able to integrate various rate. Adopting the EER (Equal Error Rate) metrics, devices such as touch-screen, printers, cameras, widely accepted, and taking as a reference Unibo’s microphones, media recorders, presence sensors, ranking, the intention is to achieve, in relation to that bank card and bar code readers, and coin and note rate, an EER lower than 0.9 per cent. The second ob- collectors, among others. jective is to increase the availability of the Griaule AFIS using the cluster concept, guaranteeing the sys- tem’s continuity in case of the failure of one of its ser- IrisVision - The Eyes vers. The improvement in recognition involves the of Your Business pre-processing of the digital images, the treatment of 323 distortion and the segmentation of the images and Coordinator: the use of morphological information, among other Jean Paulo Agostinho topics. As for the increase in availability, the develop- ment of a search queuing scheme, fault tolerance and Company: load distribution is envisaged. The expected result is JM Technology e Systems Ltda. a piece of AFIS software suited to the Brazilian rea- Approved value: lity, at a low cost and of high quality. Phase 2: R$ 150,950

There is a lack on the market today of a technol- Design and Construction of ogy which can indicate what a user does after his 322 Self-Service Intelligent Kiosk authentication and authorization to enter a system. for Demonstration, Adaptation It is not known whether he uses it effectively or and Commercialization appropriately, nor is it known how much his pro- of Spectacles On-line cessing of data costs the company. The objective of this project is to create a new technology capable of Coordinator: tracking the user’s behavior in a particular applica- Jarbas Caiado de Castro Neto tion. To achieve this, an experimental approach will

Translating Research into Business • 213 be used, in which various data-capturing techniques trolled during the vulcanization and kept stable dur- will be employed to create the user personality in a ing the entire repair process. system. Given the large amount of data to be stored, it will be necessary to use advanced techniques of data storage and compression. The expected result is Ultra-Sound Tartar a prototype which demonstrates that the technology 325 Remover for developed is able to detect a divergence in the user’s Use in Dentistry behavior. In this way, it will be possible to avoid the loss of resources and enable swifter preventative Coordinator: and/or corrective actions in the case of improper José de Jesus Capellaro access or fraud, minimizing the negative impacts the Company: company could suffer. GGDent Comércio e Serviços de Artigos e Equipamentos Odontológicos Ltda. Development of a Process Approved value: 324 to Hot Vulcanize Ten Tires Phase 1: R$ 24,113 Simultaneously, Research into the Heating Curve Parameters This project aims to research and develop an During the Vulcanization Process ultra-sound tartar remover for use in dentistry, for Retreaded Tires, with employing totally national mechanical and electron- Automation of the Machine ic solutions. The equipment used to remove tartar, also known as scalers, come in two types: pneumat- Coordinator: ic or ultra-sound. The latter offers advantages in Jorge Hideyassu Chinen terms of durability and efficiency, but is inaccessible to most dental surgeons due to its high cost. The Company: research and development of this equipment will Camelback Comércio de Pneus de Santos Ltda. operate on five work fronts involving: 1) ultrasonic Approved value: scaler: uses piezoelectric elements, mounted in a Phase 2: R$ 221,494 mechanical unit suitable for the handling and refrig- eration of the whole device (hand-piece); 2) tips: The observation of the inefficiency of a project these are attached to the ultrasonic scaler, and can with more than 40 years without innovations and offer different formats depending on the procedure the evidence of constant customer complaints about to be applied. Different models for tips will be devel- the guarantee of a repaired product which often last- oped, involving research on materials (steels) and ed only a few days, led the company to the decision hardening processes suited to their use; 3) solenoid to develop new methodologies to refine the tire vul- valve: used to control the flow of water; 4) micro- canization process. This project’s objective is to controlled electronic control module: responsible build a piece of equipment to hot vulcanize ten tires for the control of the solenoid valve and the high simultaneously and introduce a vulcanization con- tension generator, necessary for the functioning of trol system by means of monitoring of the heat the ultra-sound scaler (approximately 500 volts); curve of the camelbak, with the automation of the and 5) cabinet: in which the electronic control mod- equipment. In this way, the intervention of operators ule, the solenoid valve and the hand piece (contain- during the process is reduced and the quality of the ing the ultrasound scaler) are stored. final product is guaranteed, since the software devel- oped accompanies the entire operation, correcting the temperature and the vulcanization time neces- Development and Manufacture sary to guarantee the uniformity of the repaired tire. 326 of Mono and Bi-Propellant A system was developed of doing away with two Injectors for Low Thrust Thrusters accessories which are used during the conventional Produced Through the Process process, allowing for all ten repaired tires to main- of Solid State Diffusion Soldering tain the same internal pressure by means of com- partmentalization. Thus, all the tires are brought Coordinator: together in a single pressure chamber, which is con- José Nivaldo Hinckel

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Company: advanced signal treatment options. The question is Diprofil Forjamento Rotativo Ltda. that DM42 can only cope with acoustic emission signals, because the hardware adopted is cheaper Approved value: and more limited regarding signal treatment Phase 2: R$ 304,480 options. With this project, the company proposes the first high frequency acoustic emission monitor- Recent advances in the development of apogee ing system to use digital processing of signals (DPS). motors installed in artificial satellites have created an In its first phase, the objective of the project was to ever greater demand for highly reliable, low weight verify the technical viability of using modern and bi-propellant injectors with reduced energy con- inexpensive versions of DPS systems for application sumption. Since such components are produced by in monitoring processes. The new system needed to refined machining processes and electro-erosion, be flexible enough to have its filtering parameters creating a complex network of interconnected cuts defined by software, or even the execution of Fourier and cavities crucial to their functional performance, transformations for the analysis of processes in a low distortions, obstructions and any sort of plastic cost piece of equipment. This first phase of the pro- deformation stemming from the conventional sol- ject was approved and concluded successfully, and dering process must be avoided. This project is the proposal for phase 2 is to carry out research on aimed at the development and manufacture of these the definition for a prototype of the entire system. injectors, which consist of three plates produced This new prototype should be tested in production from a nickel-based superalloy (Inconel 600). When environments to examine the new functionalities soldered together, they make up two independent that could be applied. internal circuits, into which anhydrous hydrazine is injected into the fuel circuit and nitrous tetroxide into the combustion circuit. These fluids, when they combine, produce a spontaneous reaction thus pro- Development of ducing the burn which initiates the functioning of 328 Gravimetric Titrator the motor and generates a thrust capable of stabiliz- ing the entire satellite and dislocating it from an Coordinator: elliptical orbit into a circumferential orbit. This sol- Kenneth Elmer Collins dering technology, besides being promising for Company: aerospace application, can also be used in medical Tech Chrom Instrumentos Analíticos Ltda. implants and in the automobile industry. To date, no devices with such flight qualified characteristics exist Approved value: in the national market. Phase 2: R$ 145,703

The titrator employs a gravimetric burette, which Development of a holds some beakers with different titration solutions 327 Monitoring System attached to the weighing chamber of an electronic for Multisensors balance at the base of the chamber. The addition of solutions is controlled by electromechanical valves. Coordinator: The titrator carries out potentiometric, biampero- Juarez Felipe Junior metric, spectrophotometric analyses, standard addi- tion and preparation of standardized solution. The Company: main advantages of the gravimetric titrator are the Sensis São Carlos Indústria e Comércio absence of error caused by differences of viscosity in de Equipamentos Eletrônicos Ltda. the solutions, as well as volumetric variation due to Approved value: thermal dilation, when dispensing calibration from Phase 1: R$ 47,000 glassware. The use of the electronic balance provides Phase 2: R$ 207,200 fast, automated results, controlled by a microcom- puter, in addition to offering reproducibility and Supported by FAPESP,Sensis developed the basis precision unobtainable by volumetric methods. The of the DM42 product, an acoustic emission monitor prototype tested consists of a metal support struc- which is on the market today. Currently, other com- ture, with a capacitive sensor installed in the upper petitor companies are manufacturing monitoring part and it operates with a load capacity of 100 systems which enable multisensor functions and grams and sensitivity of one milligram. A mechani-

Translating Research into Business • 215 cal arm links the sensor to a suspended platform Platform (PMM), under contract from the Brazilian with the beakers of solution, made of teflon. The Space Agency, and is interested in qualifying and beakers have in their base, an air admission orifice to supplying its own 5N thrusters, now in develop- compensate for the entry or exit of solution via cap- ment, for this program. In order for these thrusters illary tubes connected to three-way valves. The nor- to meet the PMM requirements, they need to be mally open exit position of the valves is joined by subjected to an extensive qualification program, capillaries to two-way valves connected to the exter- involving manufacturing processes, functional per- nal reservoirs. When one of the two-way valves is formance, environmental compatibility (vibration switched on, the corresponding solution flows from and thermic) and durability in the specified opera- the reservoir into the suspended beaker, filling it. tion regimes. In addition to this, their propellant When one of the three-way valves is switched on, the injection system needs to be refined, so as to reduce solution contained in the respective suspended beaker internal tensions on the catalytic bed, creating favor- is released, by gravity, into the reaction beaker by able conditions for the use of catalyzers with less means of capillary tubes. The transferred mass is mechanical resistance. There is also interest in monitored by the gravimetric sensor and the entire nationalizing the iridium catalyzer supported on operation is controlled by software. The internal porous aluminum, a strategic component in the beakers have the lower level of solution monitored thruster which, historically, has been imported from by optical sensors, and they fill up automatically. the United States under strict controls by that coun- The upper level is controlled by means of the mass try. It is proposed therefore, to carry out a qualifi- of solution admitted. The communication of the cation program for the 5N thruster and national titrator with the microcomputer is performed via an catalyzer divided in the following stages: 1) develop- RS232 serial interface. The automated gravimetric ment and functional and pre-qualification tests of analysis, proposed in this project, faces competition the thruster; 2) functional tests of the national cat- from volumetric analysis, automated or manual. The alyzer; and 3) qualification tests for the 5N thruster gravimetric technique has the advantage of not and comparison between catalyzers. being subject to the thermic effects of volume dila- tion, alterations in the concentration and the viscos- ity, nor from lengthy calibration procedures. The Development of digital analytical balance, connected to the micro- 330 Anti-evaporation Mixture for computer, allows the replacement of volumetric the Conservation of Fresh Water techniques by gravimetric ones, without the disad- vantages mentioned. The drastic reduction in time Coordinator: and consumption of reagents afforded by the use of Marcos Eduardo Sedra Gugliotti the gravimetric titrator and the operational rational- Company: ization of the automated analysis offered contribute Lótus Química Ambiental Ltda. to the swift off-setting of its cost. The popularization of automated gravimetry depends merely on the Approved value: commercial availability of the equipment. Phase 1: R$ 37,100 Phase 2: R$ 230,650

Development and Qualification of Faced with the supply crisis in some regions of 329 5N Mono-Propellant Satellite Thruster Brazil and in the world, the company realized that the conservation of fresh water has become a busi- Coordinator: ness opportunity. This project describes the final Lauro Benassi stage of development of a chemical product which uses the technology of the formation of Company: monomolecular films of biodegradable surfactants Fibraforte Engenharia to reduce water evaporation. The product should be Indústria e Comércio Ltda. used in minimal quantities, will not harm the envi- Approved value: ronment and can be applied in electricity generation Phase 2: R$ 293,500 reservoirs, the public supply and irrigation. The tar- get public ranges from governmental agencies to pri- Fibraforte is responsible for the supply of the vate electric energy businesses, in addition to rural Propulsion Sub-system for the Multimission producers. In the second phase of the project tests

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will be carried out on the process of batch manufac- subsequent mastery of these techniques, rhodium turing, with batteries of toxicological and physico- may be transformed into other salts. chemical tests to characterize the mixture, and experiments in evaporation reduction in the labora- tory and in the field. Experiments in lakes or reser- Development of New voirs should reveal the efficiency of the product in 332 Functionalities for real conditions. The reduction in evaporation will be Toplmplant Equipment determined by existing well-established methods using, principally, class A evapometers. It is believed Coordinator: that this product should have a high socio-econom- Mario Alexandre Gazziro ic impact, especially in regions where there is a Company: shortage of water, such as the North-East of Brazil. Adiel Comercial Ltda. Approved value: Development of a process Phase 1: R$ 17,240 331 for Recovery and Recycling of Rhodium from Waste Metal AdieI developed and commercialized Toplm- in the Semijewels Industry plant equipment, which meets the needs for preci- sion and durability in the national dental market for Coordinator: implantology. The aim of this project is the adapta- Marcos Spitzer tion of equipment already developed, so that it can store all the information obtained during the surgi- Company: cal procedure – currently only exhibited in real time Água Limpa - Bertazzoli & Ragnini Ltda. – and, subsequently, link this data to the results eval- Approved value: uated by the surgeon. Such information will be used Phase 1: R$ 23,700 for later analysis by the professional, as well as being able to be sent to the company’s clinical team, with This project aims to apply and refine a process the due authorization of the owner, by internet, to for the recovery of metal rhodium deriving from assist in the development of new recommendations different stages in the industrial production of se- for surgical procedures. On the basis of extensive mijewels. The process should consist of chemical or reuse of the codes already developed, it is hoped to electrochemical stages, or both combined, for the improve the equipment in question to make it more separation of rhodium from the metal substrate competitive on the international market and possi- and its transformation into rhodium sulfate. The bly, provide it with unprecedented functionalities in immediate application of rhodium sulfate will be world implantology. its introduction into electrodeposition baths for the manufacture of semijewels. In the jewel and se- mijewel industry, rhodium is deposited in fine la- Classifier/Selector Machine for yers on pieces such as earrings and rings, initially 333 Oranges Using Computational Vision made up of a base metal, generally copper. At the same time as the pieces are being covered, the tying Coordinator: wires, hooks and electrical contacts in the electro- Reinaldo Augusto da Costa Bianchi chemical baths are also covered with rhodium. The Company: last two are reused for a new electrodeposition, Digital VXIA do Brasil Automação Ltda while the tying wires are useless after removing the pieces from the hook. To reuse the rhodium fixed Approved value: on these wires, this project proposes to implement Phase 1: R$ 35,900 and evaluate different stages: to verify the purity of the starting material; to carry out the separation of The cultivation of oranges has experienced ver- the rhodium from the base metals by means of che- tiginous growth in the last few years owing to the mical or electrochemical dissolution; dissolution of increased internal and external market. Among the metal rhodium, using procedures of electrochemi- factors that have driven this expansion is the deval- cal dissolution or in melted salts; production of ued exchange rate, the policy of strengthening rhodium sulfate and purification of that salt. With exports and standardization and quality control

Translating Research into Business • 217 initiatives. One of these initiatives was the creation used for the social good. It is with these principles of the Brazilian Program for the Modernization of that the project seeks to evolve, combining efforts in Horticulture, in which a norm for the classification research, development and production in academic of oranges was established. What has prevented and security institutions as well as private enter- many producers from adhering to the program is prise. Those mentioned are represented respectively the fact that it employs human visual inspection, by collaborating teachers at the University of São which is slow, expensive and often outside the Paulo in São Carlos, by the 380th Battalion of the expected norms. This project intends to develop an MP in São Carlos and by 3WT, a company special- orange classifying/selecting machine suited to the ized in development technology. Brazilian economic reality and which complies with the established standardization system. This technological innovation is opportune given that Development of Dental no similar machine is built in Brazil which can 335 Porcelains for the Making undertake the classification of oranges not just of Dental Prosthetics according to weight and size, but also according to their visual attributes; and that, in contrast to Coordinator: imported machines, is suited to the characteristics Roberto Queiróz Martins Alcântara of the national fruit, offering local support and Company: maintenance, in addition to a price accessible to the Angelus-Lab Laboratório de Pesquisa Ltda. small to medium producer. With a prototype built and tested, which processes an orange per second, Approved value: the aim of the second phase of the project is to Phase 1: R$ 65,452 evolve to a machine capable of processing around Among the restoration materials used in den- 15 oranges per second. tistry, ceramics are the oldest and most widely used for the making of prosthetics. Ceramics offer count- less advantages, such as: extreme hardness, high Security Logistcs resistance to compression and wear, chemical iner- System Using GPS 334 tia, color stability and, principally, excellent esthetic properties. However, as it is an imported material, it Coordinator: represents a high cost, precisely due to duties and Ricardo José Martines Ribeiro the fluctuating dollar price. The development of a Company: national product with characteristics similar or Excelerator Consultoria e Serviços S/C Ltda. superior to imported dental porcelains and at a lower cost is an object of great interest, for profes- Approved value: sionals in the area as well as for society. Therefore, Phase 1: R$ 73,466.86 in the first phase of this work, physico-chemical characterizations of the main lines of commercial The aim of this project is to develop a system for porcelains used as covering for metaloceramic the monitoring and geographical location of fleets, restorations will be carried out. This will enable the in real time, using different technologies, especially definition of process parameters that will be adopt- GPS (Global Positioning System) with transmission ed in two routes of synthesis: the mixture and of data via radio connection. The system consists of fusion of oxides and processing of polymeric a hardware device which captures the data and (Pechini) precursors. Once the main physical and sends it via radio, and software, which plots the chemical properties have been reproduced, applica- referred image on a georeferenced map. The proto- tion tests will be carried out together with profes- type initially proposed seeks to solve logistical prob- sionals specialized in the area. lems experienced by the Military Police (MP) in their response to incidents, but it is a fact that prob- lems of this nature do not just hamper the police. Development of When the intended prototypes are built it will be an 336 Complementary Organic important step not just for the realization of the Foods for Children project, but also for creating a public safety tool. Faced with the concern with rising violence, the Coordinator: solution proves to be a good example of technology Rogério Lopes Vieites

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Company: companies that have optical fiber networks, among Refazenda Grumo Manufatura e which the operators of public switched telephone Comércio de Gêneros Alimentícios Ltda. networks, broadband access providers and public utility companies. FWL210-CSO should enable long Approved value: distance voice and data communication over optical Phase 1: R$ 19,800 fiber without the need for intermediary layers of communications equipment. To effect the low Fruit and vegetables are the main source of vita- capacity communication envisaged by this project, mins and obligatory ingredients on any nutritionally these layers make the investment unnecessarily balanced menu, including that of children. The ob- expensive. FWL210-CSO will also enable integration jective of the present work is to produce six com- with the customer’s PABX telephone and connection mercial types of complementary organic foods for to the public switched telephone network, allowing infants, with quality nutritional, sensory and micro- access to external connections from any node on the biological standards and with long shelf life. It network. In this way, engineers and technicians in should be stressed that organic agriculture is a broad the field will be able to communicate amongst them- and varied spectrum of practices with biologically selves, from telecommunications stations, with the and ecologically correct principles. In the prepara- company’s offices using fixed phones and external tion of these foods, products of vegetable origin will cell phones and make conference calls. The equip- be used, such as squash, white rice, sweet banana, ment will operate as open channel, in the same way beetroot, broccoli, carrot, spinach, beans, yam, lima as the electric service channels in which all the nodes orange, papaya and cassava, cultivated in the region on the network will have simultaneous access to of Botucatu (SP). Subsequently, nutritional and cen- conversation (multiple access). The Optical Service tesimal analyses will be performed, sensory evalua- Channel will also offer restricted channels, so that tion using the Moraes (1985) guidelines, and micro- the signal will be regenerated in the node without, biological analysis in relation to the parameters nevertheless, allowing local access. required by RDC nº 12, a resolution adopted by the National Agency for Health Vigilance (Anvisa), in addition to the enumeration of moulds and yeast and the standardized heterotroph counts. The com- Optical Cross-Connect mercialization of these products should be handled 338 with Liquid Crystal Based by several grocery chains, located in São Paulo and Switching Matrixes in Rio de Janeiro. Coordinator: Sergio Barcelos Optical Company: 337 Service Channel FiberWork Comunicações Ópticas Ltda. Coordinator: Approved value: Sergio Barcelos Phase 1: R$ 48,000 / US$ 8,455 Company: This project aims to develop optical cross-con- FiberWork Comunicações Ópticas Ltda. nects-OXC with switching matrixes based on liquid Approved value: crystal. The work will entail: 1) development of opti- Phase 1: R$ 35,000 / US$ 12,700 cal switches based on liquid crystal; 2) design of the cross-connect architecture using the optical switches The aim of this project is to develop a new piece created; 3) integration of the optical switches in of equipment for optical communication called accordance with the designed architecture; and 4) Optical Service Channel or FWL210-CSO, which development of the equipment’s control and man- will transmit low capacity voice and data over opti- agement interface. FiberWork benefits from collabo- cal fibers. This entails the first service channel ration with the Renato Archer Research Center designed and developed in Brazil acting in the opti- (CenPRA), internationally recognized in the cal domain on the international market. It should research and development of liquid crystals. The replace, with superior performance, the others exist- function of an OXC is to optically switch the wave- ing on the market, which function entirely in the lengths of different customers in the WDM (wave- electrical domain. This project aims to cater for length division multiplexing) optical layer. The use

Translating Research into Business • 219 of OXCs is vital for the working of dynamically Identification reconfigurable optical networks and is ideal for the 340 System for application of liquid crystal (LC) technology in the Polymorphisms OXC nucleus. This is because LC offers a perfor- mance comparable to competing electromechanical Coordinator Project: devices, yet with the reliability and efficiency of solid Zanoni Dias state devices, in addition to being transparent in Company: relation to bit rates and protocols. The OXC pro- Scylla Informática S/A posed by FiberWorks is looking to establish itself in the market of metropolitan networks, access net- Approved value: works and company networks, which use the Phase 2: R$ 93,800 CWDM (coarse wavelength division multiplexing) technology, and also in the market of long-distance The main objective of this project is to carry out networks, which use the DWDM (dense wavelength research with a view to creating a piece of software division multiplexing) technology. for the identification and analysis of single nucleo- tide polymorphisms (SNPs) which could be compe- titive on the national and international markets. Development of Material This system should combine the following advanta- 339 in the Form of Filament of the ges: 1) reliability: analyses based on advanced algo- ABS Type for Use in FDM rithms and statistical techniques; 2) speed: the data Rapid Prototyping Machines batches will be analyzed in a day (currently the ave- rage time is 15 days); 3) convenience: all the infor- Coordinator: mation required for the analysis of the batch, even Sergio Luiz Dulcini including the visualization of electroferograms, are brought together in a single piece of software; 4) Company: sharing: several researchers can work on a common Oriel Indústria e Comércio Ltda. database; and 5) versatility: application for different Approved value: types of organisms (diploids, polyploids and virus Phase 1: R$ 57,430 populations, among others.).

The submitted proposal aims at the development of consumable materials used in rapid prototyping Method for Increasing Productivity machines of the FDM type, with the aim of reducing 341 Based on the Fixation of the cost of making prototypes in Brazil and abroad. the G2 Allele in the Promoting The project involves the characterization of the mate- Region of the Growth Hormone rial through the following analyses over an ABS fila- Gene in Slaughter Cattle ment: infrared spectroscopy, capillary rheometry, per- meable gel filtration chromatography, diffractogram Coordinator: of inorganic charges, thermogravimetric analysis, Sergio Ulhoa Dani dynamic-mechanical analysis, electronic sweeping Company: microscopy, co-rotating twin-screw extrusion and GENON - Genética Molecular, sample preparation in ARBURG injector. Following Pesquisa & Development Ltda. these analyses, research will be undertaken into mate- rials of the ABS type (Acrylonitrile Butadiene Approved value: Estirene) commercialized in Brazil and sold in pellets Phase 1: R$ 38,835 used in mixture which results in a compound with characteristics similar to those of imported ABS. This Genon proposes a method of increasing produc- material will be inserted in a co-rotating extruder tivity based on the fixation of the G2 allele (or long with a cylindrical orifice die, so that in the extrusion, allele) in the promoting region of the growth hor- a cylindrical filament calibrated at 3 millimeters mone gene (bGH). The characterization and quan- thickness emerges. This filament will then be fed into tification of the gain deriving from the fixation of the FDM machine in order for prototypes to be made the G2 allele in controlled herds of three breeds of with mechanical and geometrical properties similar zebu (Nelore, Gir and Guzerá) and one bull breed to those used by an imported filament. (Caracu), will be undertaken using DNA genotyping

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by polymerase chain reaction (PCR), restriction In series with an electrolytic cell, Khemia’s equip- fragment length polymorphism (RFLP) and vari- ment envisages ionic exchange filters and an auto- ance analysis. It is estimated that between 5 to 20 per matic control valve, allowing the effluent from these cent of animals in Brazilian herds are carriers of the machines to be discarded directly into the sewers, G1 allele, a short form of bGH. With the consolidat- guaranteeing emissions always within legal norms. ed preliminary results indicating a negative effect of With consumption below 50 watts, the electrolytic this short allele on the productive characteristics of extractors should recycle the used silver photogra- slaughter herds and a positive effect of the long allele phic fixers, prolong the useful life of the fixers and on those same characteristics, animals carrying the decontaminate the waste material. G1 allele could be preferentially discarded, and ani- mals carrying the G2 allele could be preferentially bred, as part of a program of genetic improvement Project for the for increased productivity. Based on preliminary 343 Development of an results, it is estimated that the application of the Experimental On-board technique on the national herd could represent an Module on a Low Orbit annual gain of the order of 150 thousand tons of Orbital Platform – meat for the country, obtained simply by means of “Sara” Project the increase in productivity and competitiveness in the production chain. This will bring economic, eco- Coordinator: logical and social benefits to an entire sector based Alfredo Otto Brockmeyer on the agribusiness breeding slaughter cattle. Company: Brockmeyer Space Engineering Ltda. 17th BIDDING INSTRUCTIONS Approved value: Phase 1: R$ 45,700

Development of Automatic This proposal aims to design and develop an ex- 342 Electrolytic Extractors perimental on-board module (Modem) on a space for Heavy Metals in Effluents platform, called Sara, forming part of its payload. Specifically, the Modem is an integral part of Sara, Coordinator: the project developed by the Aeronautical and Space Alcídio Abrão Institute (IAE). The on-board module on the orbital platform will be launched into space by means of the Company: VS-40 sounding rocket for sub-orbital flights or by Khemia Equipamentos the VLS-1 satellite launching rocket for injection Tecnológicos de Efluentes Ltda. into low earth orbit, for a duration of approximately Approved value: ten days and controlled re-entry into the earth’s at- Phase 1: R$ 35,397 mosphere. The purpose of the Modem is to enable the setting up of scientific or commercial experi- The project aims to demonstrate the technical ments for the testing and confirmation of physical, viability of automatic electrolyzers capable of moni- chemical or biological behavior in the microgravity toring levels of silver ions in effluents. These ions are environment. These researches have a very strong present in all emissions produced by companies that market appeal, since the knowledge and the disco- work with photosensitive materials, such as hospi- very of properties intrinsic to the object of the ex- tals, printing businesses and photo labs. The elec- periment in the absence of the gravity acceleration trolyzers should operate potentiostatically or galva- factor, allows for development, discovery and im- nostatically in hydrodynamic regime, selectively provement of products. As an example new medici- electrodepositing the metal and operating in the nes, vaccines, crystal growth and protein structures flow directly at the source of the emissions, which may be cited. There are also applications in the fields are the film development machines. All the measure- of physics and chemistry, such as the improvement ment and control of the process will be carried out in the composition of fuels or the examination of automatically by a microcomputer of the PIC series. the behavior of complex mixtures of fluids.

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Manufacture pollutant, greater concern is caused by those that in- 344 of Rectangular corporate heavy metals in their composition, among Dental Thread them the fluorescent lamp, which is the second grea- test polluting source of mercury. Supermarkets, Coordinator: banks, universities, industries and commerce, are all André Itman Filho known to have a very high quantity of fluorescent lights installed and most of them are discarded im- Company: properly in sanitary landfills. Their proper disposal Tecnident Equipamentos Ortodônticos Ltda. has been the theme of studies which seek to obtain Approved value: methods of decontamination and recovery of com- Phase 1: R$ 32,700 ponents. There is no information on the existence, in the national market, of manufacturers of equipment The study of the mechanical forces in the perma- to fragment fluorescent lamps and recover the mer- nent deformations and in the breaking of dental cury. In Brazil, the companies that dispose of these thread generated an industry which uses high tech- lamps developed their own machines. For this rea- nology for the manufacture of components used in son, Tramppo Serviços Industriais intends to study esthetic restoration. The choice of the appropriate the technical viability of the development of a ma- thread is important at every stage of dental treat- chine displaying technological innovation, which ment. In the case of rectangular threads, used at the uses vacuum systems combined with high tempera- conclusion of work, the product is imported from a ture to capture the mercury in a simple, safe and few suppliers. To avoid technological dependency economic manner. For this task, the company is and to cater for the needs of dentists it will be neces- going to request the support of the Institute for sary to develop equipment capable of producing the Energy and Nuclear Research (Ipen) and the Institu- rectangular threads in the dimensions suitable for the te of Technological Research (IPT). treatments. This project was prepared with the objec- tive of developing a prototype-mill with adjustable cylinders. To establish the working parameters of the Process for Multiple Operations equipment, different stainless austenitic steel wires of 346 of Sterilization, Homogenization, the 300 series will be milled for rectangular transver- Inoculation and Packaging, sal section. The microstructures and the final mecha- Aimed at the Production of nical properties of the products will be evaluated af- Inoculants for the Cultivation of ter processing. In this stage, the control of procedures Edible and Medicinal Mushrooms and the production of threads which conform to the normal specifications will be important. Based on Coordinator: these results, a new project will be proposed with the Augusto Ferreira da Eira objective of building an industrial mill for the pro- Company: duction of threads on a commercial scale. Fungibras - Indústria e Comércio em Fungicultura Ltda. Appropriate Disposal of Approved value: 345 Fluorescent Lamps Phase 1: R$ 68,700 which Contain Mercury Phase 2: R$ 290,000

Coordinator: The company intends to develop a technological Atsuko Kumagai Nakazone innovation which aims to produce agricultural ino- culants and substrates for the axenic cultivation of Company: edible and medicinal mushrooms at substantially re- Tramppo Serviços Industriais Ltda. duced cost and with greater guarantee of microbiolo- Approved value: gical quality. This entails a process of mass dynamic Phase 1: R$ 55,762 sterilization, with equipment which enables multiple operations: homogenization of raw materials, coo- Economic development in the last century, com- king, sterilization under continuous homogenization bined with high indices of consumption, have trans- (avoiding mass transport problems), cooling, inocu- formed pollution into one of the major environ- lation and homogenization of the inoculant, extru- mental problems. Among the various types of sion and packaging of the inoculated substrate

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(seed). In the first phase of the project, this process zation of the material and in its grinding so as to ob- was compared with the conventional method of pro- tain the desired granulometric distribution. It is ho- ducing inoculants by static sterilization in autoclaves. ped, at the end of the project, to introduce on the The results obtained proved the technical viability of market the first national product for the treatment the operation and control of the new equipment in of dentinary hypersensibility based on the concept the production of inoculants, reducing the time/ste- of bioactive materials, offering greater practicality of rilization temperature binomial, contaminations the application, greater comfort for the patients and from thermo-resistant bacteria and practically elimi- the lasting elimination of the problem. nating fungal contaminations. This stage also per- mitted the fast cooling, the inoculation and homoge- nization of the inoculant and the extrusion of the Standardization and inoculated substrate (cereal grain). These advantages 348 Validation of an Elisa Kit for the will permit an initial reduction on costs of the order Quantification of Chloraphenicol of 40 per cent compared to the conventional process. in Products of Animal Origin However, on this scale (prototype with 850 liter capa- city), it was not possible to operate the process for the Coordinator: production of substrates aimed at the axenic cultiva- Cyro Ferreira Meirelles tion of mushrooms. Thus, in phase 2 it is intended, Company: among other activities, to build full-scale equipment, Ata Análise Tecnologia Comércio with around 4,500 liters. Representações Ltda. Approved value: Development of Optimized and Phase 1: R$ 50,300 / US$ 5,931.22 347 Economically Viable Process for the Production of Biosilicate for The control of toxic residues in agricultural and Treatment of Dentinary Hypersensibility livestock products is the responsibility of the Mi- nistry of Agriculture, which up until now has not Coordinator: carried out a significant statistical assessment of the Christian Ravagnani annual herd slaughtered. The justification would lie in the fact that there is no national laboratory for the Company: production of kits and in their high import cost. Vitrovita - Instituto de Inovação Meat importing countries in the European Union do em Vitrocerâmicos Ltda. not accept departures from health norms due to pre- Approved value: vious problems with the spread of diseases in their Phase 2: R$ 279,000 / US$ 7,118.64 herds. In addition to exaggerated reservations in the market, the present situation is at emergency level The scientific and business communities have with regard to agricultural products such as soya, put a lot of effort into the search for more satisfac- coffee and fruit and vegetable farmers. One of the tory products for the treatment of dentinary hyper- areas of research being pursued in the Laboratory sensibility. Vitrovita’s researchers developed on a la- for Animal Nutrition in the Center for Nuclear boratory scale, an innovative bioactive crystalline Energy in Agriculture (CENA), of the Luiz de Quei- material, called biosilicate, which demonstrated ex- roz Agricultural College in the University of São cellent preliminary results in research in vitro and in Paulo, involves the standardization of Elisa kits for vivo in the treatment of this hypersensibility. The the detection and quantification of toxic residues in objective of this project is to develop and optimize, farming and livestock products. The Ministry of up to pilot scale, an economically viable process for Agriculture’s accreditation process, necessary in or- the production of biosilicate. The level of bioactivity der to begin commercial production of the kits, re- of the material should be maintained in this stage, quires the standardized methodologies to be valida- along with the percentage of crystallinity and ted. Given that CENA’s laboratories are not adequate crystalline phase and the purity and granulometric for international quality control systems ISO 17025 distribution appropriate for its use in the treatment and BPL, a partnership has been signed with Ata and elimination of dentinary hypersensibility. To Análise, which possesses the technical infrastructure achieve these objectives, the company will develop and commercial experience necessary for the accom- research on the fusion of biosilicate, using different plishment of the project. crucibles in the thermic treatments for the crystalli-

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Innovation in the Production mers, transforming a medium such as the videogame 349 Process of Composts into a space for advertising is something simple, but for Special Edible Mushrooms there are two limiting factors: geographical locality and the time zone of the adverts. This project propo- Coordinator: ses a framework which, in addition to allowing deve- Denise Terezinha Barnabé Abackerli lopers to create network games almost as though they Company: were stand-alone, also delivers the functionalities Zucca Alimentos Ltda. which the company calls “game-commerce”: a virtual community which revolves around the movement of Approved value: credits through the sale of games items or personali- Phase 1: R$ 30,106 ties and through the showing of adverts. Game-com- merce solves the geographical and time location pro- The consumption of edible mushrooms has been blems of commercials in games. The idea is to use the increasing throughout the world, whether because of servers which manage competitions and handle the its high culinary appeal, or its nutritional value, sin- sale of items and personalities to exhibit the adverts ce it contains a high number of proteins and low or also. The objectives of the project are: 1) To research non-existent levels of fat. Mushroom production in- a peer architecture for distributed entertainment sys- volves the creation of a favorable environment for tems (multiplayer games); 2) To study the technical their development (temperature, humidity, light, air) viability of using the architecture with the hardware and a supplement of nutrient material (compost) to and network resources available on the market; 3) To help it develop. For its production on a commercial create a methodology for the distribution of adverts scale, the combination of these factors should allow in online games; 4) To implement a draft version of for the growth of the fungus to be controlled so as to the framework; and 5) To create a game prototype to synchronize market supply and demand, imposing test the implemented functionalities. additional conditions on the production time and cycle. Research carried out confirms the technical viability of the use of alternative materials in the pro- Development of Continuous duction of compost and Brazil is a favorable place for 351 Production System these developments, given the abundance of alterna- for Torrefied Briquettes tive materials. However, the majority of studies limit themselves to concepts on laboratory scale. As a re- Coordinator: sult, this project intends to develop the production Félix Eliecer Fonseca Felfli process of composts for the (Lentinus edodes) and (Pleurotus ostreatus) shitake species, using alternative Company: low cost materials available in the country. It is fur- Bioware - Tecnologia de ther proposed to test the compost with alternative Termoconversão de Biomassa S/C Ltda. materials for the Oudemansiella canarii (Ruegger, Approved value: M.J.S. 2001) variety, native to Brazil, assessing in ad- Phase 1: R$ 48,172 dition its commercial growth in the environment al- ready developed for the cultivation of the hiratake. This project aims to develop a production system for torrefied biomass briquettes by means of the in- clusion of a continuous torrefier in traditional bri- Middleware for High quetage plants. The proposal is based on results obtai- Performance Electronic 350 ned earlier, in which it was proved that torrefication is Games on Network a procedure capable of improving the energy charac- Coordinator: teristics of biomass briquettes, preserving their main Fábio Feital de Carvalho mechanical properties. A system of this type is capa- ble of manufacturing highly standardized briquettes Company: and with a high energy content, that’s to say, a better Tempo Soluções em Informática S/C Ltda. quality product for industrial, commercial and do- Approved value: mestic use with export potential. The objective of this Phase 1: R$ 9,500 / US$ 1,490 phase of the project is to research the technical viabi- lity of the proposed system, envisaging three funda- Electronic games sell millions of copies world mental steps for this. The first concerns the study of wide. To take advantage of these potential consu- biomass residues (raw materials) and efficient tech-

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nologies for the production of briquettes more suita- Company: ble for the torrefication process. In the second stage, KIais Soluções Consultoria e Desenvolvimento torrefied briquette samples will be produced to cha- Ltda. racterize them and study their performance during Approved value: their combustion in industrial, commercial and do- Phase 2: R$ 109,825 mestic ovens. In the third stage the most appropriate variants for continuous torrefication will be studied. The first objective of this project is to develop a As a result, it is hoped to obtain the preliminary de- platform for the automation of company processes sign of a continuous torrefier, including the principal based on the rules of business. The idea is that, even control mechanisms for temperature, transport and without software knowledge, a person may be able to cooling of the torrefied briquettes. create an internet-based system that will allow the users who carry out activities involved to interact in a differentiated manner, according to their roles in Production of the workflow. The systems generated are based on Polyclonal Antibodies 352 Java and can be used on multiple platforms, inclu- ding those based on freeware. Another objective is to Coordinator: offer a friendly interface, based on international Fernanda Alvarez Rojas standards defined by the Business Process Manage- Company: ment Initiative (BPMI) for the description of com- Imuny Biotechnology Produção e Comercialização pany processes. In this way, the companies will be de Anticorpos para Biotecnologia Ltda. able to document them and redesign them easily, guaranteeing that the information technology tool Approved value: keeps pace with the dynamic of the company pro- Phase 1: R$ 3,625 / US$ 15,400 cesses and brings effective and long-lasting benefits to its management. The development of this product Functionally antibodies can be characterized by is based on a workflow administrator created by the their ability to recognize and bind with certain anti- company and now in commercial use. The new ad- gens which form antigenic determinants. Taking ad- ministrator, being based on open and already con- vantage of the physiological function of antibodies’ solidated technology, should have a lower cost, humoral immunological defense, these antibodies, which will place it within reach of smaller sized com- when produced in animal serum, can be used as im- panies, giving them access to management concepts portant tools in some biological techniques for scien- through processes which represent an effective way tific research and in tests for diagnostic purposes. of gaining and retaining competitive advantage. Polyclonal antibodies are very valuable in the techni- ques of immunoprecipitation, immunoblotting, im- munohistochemistry and Elisa (enzyme-linked im- Concentrator of Fixed munosorbent assay). The usual method for obtaining and Mobile Telephone antibodies involves immunization with a preparation 354 Services - CFM of pure or partially purified antigens. Thus, the pre- sent project aims to set up a laboratory for the deve- Coordinator: lopment of the technology for the production of George Emmanuel Bozinis polyclonal antibodies for use in scientific research. It is also intended to make viable the production of the- Company: se antibodies on a scale with commercial impact, Innovatech Telecom Indústria e Comércio de with a substantial reduction in costs and acquisition Equipamentos Eletrônicos e de Telecomunicações time compared to those currently imported. Approved value: Phase 2: R$ 234,800 / US$ 17,575.76 Generator of Systems for This project aims at the development, in an inno- Business Processes Based on BPM vative way, of a system for integration of the fixed and 353 (Business Process Management) cell phone networks. Called Concentrator of Fixed and Mobile Telephone Services – CFM, the system Coordinator: consists of a low cost piece of equipment for the indi- Fernando Antonio Vanini vidual or corporate end user. The CFM allows the fi-

Translating Research into Business • 225 xed telephone and mobile phone user to access the fi- test), which are the object of this project. The preci- xed network from his own cell phone terminal if he is se diagnosis of canine monocytic ehrlichiosis is ob- located within the area covered by the CFM, thus en- tained from suitable clinical and laboratorial evalua- joying fixed network rates in those conditions. On tions and its confirmation can be obtained with leaving the area covered by the CFM, the user can ac- indirect sorological tests. In this project, a lineage of cess the mobile cell network in the normal way. The canine cells DH82 cultivated in vitro will be infected user’s terminal camps in the CFM control channel if with a strain of E. canis, isolated by Machado (1993). it is within the CFM catchment area. When the termi- From these cells antigenic substrates of E. canis will nal moves away from CFM by means of the GSM re- be prepared, aimed at the production of sorological select control channel, it will camp in the local opera- tests. With this proposal the intention is to innovate tor’s mobile system control channel. Thanks to this in the area of veterinary medicine and, at the same functionality, no additional development will be ne- time, to cater for a repressed demand which arises cessary at the mobile terminal, facilitating its imple- from external scientific dependence and the absence mentation for the user and for the operating compa- of biotechnological development. nies. CFM consists of a concentrator device which interconnects with the fixed network and has an aerial interface compatible with the GSM standard. The in- System for terconnection with the fixed network can be analogi- 356 Measuring Real cal, with line signal equivalent to that of the fixed line Time for Swimmers subscriber, allowing a single user to access this net- work at a particular moment; or digital, with an Coordinator: ADSL modem, allowing the multiplexing of the subs- Humberto Ribeiro de Souza criber line by more than one user simultaneously. Company: Mateus Rodrigues & Ribeiro de Souza Ltda. Development of Kits for Approved value: 355 Immunodiagnosis of Canine Monocytic Phase 2: R$ 61,065 Ehrlichiosis, Using the Techniques of Indirect Immunofluorescence The objective of this project is to develop a sys- (RIFI) and Indirect Immunoenzymatic tem capable of evaluating the performance of top Tests (Dot-ELISA and ELISA-test) swimming athletes. By means of wireless sensors op- tically linked to the side wall of the first lane of an Coordinator: Olympic swimming pool, a microcontroller measu- Gisele Maria de Andrade res the instant velocity of the swimmer on the basis of the distribution of sensors in the pool, and the Company: speed which the athlete is achieving. The data calcu- IMUNODOT - Indústria e Pesquisa de Produtos lated by the microcontroller is passed through a mi- para Diagnóstico Ltda. crocomputer which has a program which stores the Approved value: data referring to the athlete and calculates the deri- Phase 1: R$ 39,693 vative of the acquired velocity, thus obtaining the exact position of the swimmer in the pool. With this Ehrlichia canis (Anaplasmatacea, Rickettsiales) is information to hand, a qualified trainer can inter- the etiological agent of canine monocytic ehrlichio- pret the curves generated, checking the points of sis, being an obligatory intracellular bacteria which greatest attrition in the length, the swimmer’s fluc- infects monocytes and macrophages of the phagocy- tuation and errors in specific activities such as turns. tary monocytic system. E. canis, which has a world- The system was evaluated on equipment developed wide distribution and causes high morbidity and with scientific test wire and software, displaying mortality in endemic regions, is one among the ex- good results. With its technical viability and marke- tensively studied ehrlichiosis organisms. In the last tability proven by the company, phase 2 of the pro- two decades, ehrlichiosis organisms have been iden- ject aims to transform it into a commercial system. tified infecting human beings. The detection of E. To do this, the interface needs to be practical, wire- canis antibodies can be carried out using the indirect less and provide precise results. In addition to the in- immunofluorescence test (RIFI) and the indirect ternal market (swimming centers which train athle- immunoenzymatic test (Dot-ELISA and ELISA- tes for competitions at home and abroad), the

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company also intends to launch the product on the Company: international market. Orbisat da Amazônia S/A - Divisão de Engenharia - São José dos Campos Approved value: Development of a Low Cost Phase 2: R$ 318,400 357 System for the Supply and Presentation in Various Media – Network, Internet, Orbisat developed Brazil’s first Interferometric Palm, PDA, Cell Phone, etc. – of the Synthetic Aperture Radar, OrbiSAR-I, which opera- Strategic and/or Performance tes on two different bands. Band X produces images Indicators of an Organization to its of the surface and Band P has the capability of pro- Executives and/or Owners of Processes ducing images of terrain under dense vegetation (fo- rested areas). The processor for the detection of oil Coordinator: spills, proposed in this project, will be an OrbiSAR-I João Antônio Mattei implementation. At present this radar records data Company: obtained on hard disks and only at the end of the Nacional Bureau de Serviços NBS Ltda. flight is it copied onto equipment that will process it. The project proposed here basically entails enabling Approved value: OrbiSAR-I Radar to process raw data in real time, Phase 1: R$ 34,400 that’s to say, as the data is gathered it could begin to be processed instantaneously during the flight. This The swift visualization of strategic indicators for represents an enormous technological innovation, decision making is one of the critical factors of orga- given that commercial sensors capable of producing nizations’ success. The proposal of this project is to high resolution SAR images (in the order of 10 me- develop the functional specification for a system ters) in real time and at low cost do not exist. To do which is low cost, extremely easy to install, to use this, the hardware will need to be adapted by the re- and to maintain and which enables the creation and placement of two processing boards with other more visualization of strategic and/or performance indi- modern boards in the Flight Computer Controller cators of organizations through various means of (FCC) unit; and the construction of the antenna with communication, promoting access to information new parameters already defined, to be carried out by any time anywhere. In other words, the aim is to de- Orbisat in partnership with the State University of velop a management control panel (Management Campinas (Unicamp). The software will require the Cockpit) for micro and small businesses, compatible development of a real time processing algorithm. with the predominant technology in that environ- ment. The proposed specification should cover the following strategic aspects: 1) description of the Process for the Obtaining, standard-user profile which will serve as a reference Composition and Use of a System point for the definition of the system’s functionality 359 of Recombinant Hormones and its installation and maintenance cost; 2) system for Superovulation in Vertebrates model, bearing in mind a) principal sources of data which it will support for the formation of indicators; Coordinator: b) operational flow; c) treatment of deviations, case Jorge Luiz Pesquero histories and warnings; d) means of visualization and compatible interfaces; e) scalability; f) technolo- Company: gical environment required; and 3) script for inte- Proteobrás - Desenvolvimento ractive video for training in the installation, use and Biotecnológico Ltda. maintenance of the system; formation and configu- Approved value: ration of the organization’s strategic indicators. Phase 1: R$ 75,000

The present proposal aims to establish in the city Processor of Mogi das Cruzes a company specialized in the pro- For the Detection 358 duction of biotechnologies, specifically proteins for of Oil Spills application in laboratories carrying out research, both in human health and in the veterinary field, with em- Coordinator: phasis on the use of genetic recombination. It is inten- João Roberto Moreira Neto

Translating Research into Business • 227 ded, for this purpose, to establish a structure for the nia-based mixtures containing different quantities manipulation of genes of different animals. These ge- of dopants capable of coloring the molds of both. nes should be introduced in specific vectors and the- se vectors inserted into genome cells or microorga- nisms which, in the process of fermentation, will Single Dose proceed to express the respective gene, in this way 361 Vaccine Against producing the desired protein. It is also intended to Bovine Tick establish the entire structure of the test of biological Coordinator: activity for these products and, in aseptic conditions, José Maciel Rodrigues Junior prepare for their use in animals and/or humans. The group has been working for years in this field, having Company: produced proteins of high economic potential, for Nanocore Biotecnologia Ltda. example: bovine and equine follicle-stimulating hor- Approved value: mone (FSH), activin, inhibin and proteins homolo- Phase 1: R$ 99,840 gous to angiostatins. Based on the angiostatin sequen- ce, the group cloned and expressed a variety of this Economic losses caused by ticks are difficult to protein and proved its antitumoral effectiveness in ex- evaluate, but it is estimated that in Brazil they reach a periments involving different animal species. figure of US$ 1 billion, taking into account the loss of production of milk, meat and leather, mortality, the reduction in birthrate and the consumption of anti- Development of tick insecticides, among others. The existing recombi- Dental Ceramics Based 360 nant vaccines against the Boophilus microplus tick are on Alumina and Zirconia imported and give a level of protection which varies between 50 and 70 per cent, but several application Coordinator: doses are needed, which raises the cost of administra- José D´Amico Neto tion. Due to this, researchers from Nanocore, in part- Company: nership with the Cuban Center for Biotechnology, Tecnident Equipamentos Ortodônticos Ltda. holders of the commercial rights to the Gavac vacci- ne, developed two products which were patented and Approved value: are in the optimization and pre-clinical evaluation Phase 1: R$ 74,400 phase. The first of these is an annual single-dose for- mulation and the second is an annual single-dose for- The orthodontics components sector has come mulation associated with antiparasitics of a broad on a pace in Brazil in the last ten years. It is estima- spectrum and wide use. This project aims to develop ted that this market turns over around US$ 100 mil- the large scale production of microspheres containing lion annually and, of this sum, 40 per cent represents a recombinant protein, Bm86, associated with active the participation of Brazilian industry, which manu- broad spectrum immuno-enhancing drugs against factures a very large range of once imported pro- ectoparasites, capable of providing a more effective ducts. These include metal alloys, amalgams, com- response and offering greater facility in the manage- ponents such as metal braces, cement and materials ment of animals. The advantage of an offer such as for the treatment of dental canals. However, the vast this should, above all, take into account the profile of majority of ceramic-based products are still impor- the technology platform, since it should be possible to ted, such as ceramic braces, dental porcelains, cera- obtain different medicines and vaccines to meet the mic enamels and various types of cement and molds diversified demand for products of this nature. for precision dental casting. The objective of this project is the development of alumina and zirconia based ceramic braces. Alumina is proposed as the Generation of Graphical Interfaces base ceramic to be used in the production of colored 362 for Parallel Real Time components, much sought after in dental surgeries Applications Based on Source Code by children and adolescents who undergo treatment for orthodontic correction; and zirconia, as a base Coordinator: for the production of components with colorations José Roberto Pinto Ribeiro which approximate to the different natural tones of teeth. In order to achieve this, studies will be under- Company: taken on the synthesis of alumina-based and zirco- Eonic Brasil Ltda.

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Approved value: tracted information which served as the parameters Phase 2: R$ 20,400 for the idealization and conception of a product wi- thout equal on the market. The mini-washing ma- The reduction in the cost of processors and the chine will have a wash capacity of 3.5 kilos of clo- emergence of faster networks to connect them has thes, in addition to being an economic, practical, enabled the construction of powerful parallel sys- efficient and modern product. The mini-washing tems, capable of supporting applications which han- machine, the prototype of which is in the test phase, dle large volumes of data and demand high proces- reduces by around 40 per cent the dimensions and sing capacity. These systems have been used in an weight of the current 5 kg machines, and for this rea- increasingly large number of areas, but, despite this, son it optimizes valuable resources such as water, parallel programming has proved to be much more electrical energy and space. One of the most impor- complex than sequential programming, mainly be- tant innovations is the new electric motor, which cause it involves the need for synchronization bet- should be attached to the lid. In this way, many of ween processes and the analysis of data dependence. the mechanical components needed for the move- To overcome this difficulty, Eonic Brasil created a ment of the wash tank, such as driving belt, pulley, graphical environment called VisualRT, the objective gears and gear shift are done away with. The consu- of which is to assist in the development, documenta- mer will be able to buy a mini-washing machine in tion and visualization of real time applications run any supermarket and transport it easily. In addition, on parallel machines. With this tool, the user deve- the simplicity of its construction reduces the cost of lops a graphical model of the real time system capa- production significantly. ble of representing the parallelism and the temporal restrictions present in these systems. Based on this model, VisualRT automatically generates source Provision of code, builds the executable files and runs the appli- 364 Dental Accessory cation. Although VisualRT offers a high level interfa- ce for the management of parallel real time systems, Coordinator: the consumer market for the tool is composed main- Miriam Nakatani Miqui ly of companies that still have a significant quantity Company: of applications developed through textual interfaces. DDS Produtos Odontológicos Ltda. So that these companies can have access to the ad- vantages offered by VisualRT for the maintenance of Approved value: their systems, they need an effective system to map Phase 1: R$ 69,200 out the textual interfaces in the equivalent graphical Nowadays, the traditional orthodontic brace with representation. The objective of the present proposal 0.18 and 0.22 slots has various limitations. The slot, in is the creation of a piece of software to automate this combination with the wires, determines the strength. mapping. It should produce graphical representa- A 0.18 brace will take a wire of 0.18 height and 0.25 tions of parallel real time systems based on the sour- depth, and the 0.22 support will take a wire of 0.22 ce code of these systems, freeing the user from the height and 0.25 depth. Depending on the phase, the- task of carrying out the conversion manually. re are different techniques which use different diame- ters for certain modifications, always limited to the Mini-Washing size of the slot. This project aims to facilitate the use 363 Machine of the 0.18 and 0.22 wires, developing a brace capable of working with both. The traditional brace has 16 Coordinator brackets in contact with the soft tissue of the mouth, Marcelo Monteiro while the brace planned by the company will have just four brackets, which will provide four times the level Company: of comfort. Besides this, the traditional brace that will Santos Dumont Criação e Design Ltda. be developed will eliminate the need for elastics or Approved value: wire ligatures to be tied to the arch wire due to a new Phase 2: R$ 196,331.92 clip system which decreases the accumulation of pla- que and the risk of tooth or mouth disease. Initially, it This project proposes a new concept for washing will be necessary to identify the best material for the machines. The company researched and compared manufacture of the product, which will be developed the main systems (tumbling and agitating) and ex- with milling techniques to guarantee greater precision

Translating Research into Business • 229 and flexibility in the manufacturing process. This Company: technique, however, does not appear so efficient when Gepco Indústria e Comércio Ltda. used for mass production. Thus, in the second stage of Approved value: the research, mill rolling techniques will be used to Phase 1: R$ 62,616 / US$ 3,900 guarantee productivity and economic viability. The objective of this project is to develop a line Optimization of Production of high performance products for personal and 365 Process for Large Scale Gain vehicular protection, using a system of laminated in the Micropropagation of Plants materials consisting of ceramic (alumina) on the im- pact side and with a high-performance fiber cove- Coordinator: ring for the backing material. The use of ceramics Monique Inês Segeren for ballistic protection began in the 1960s, but what little information was available in the literature did Company: not demonstrate how to prepare a product with ProClone Biotecnologia Ltda. high performance and which had a price favorable Approved value: to commercialization. Phase 1 of this project invol- Phase 1: R$ 69,000 ves: 1) ceramic level: commercial ceramic products made from alumina will be tested in the form of six- In order to have access to the international flower sided tiles, in sheets and samples will systematically and fruit markets, which turn over around US$ 86 bil- be prepared with different purities and microstruc- lion in the entire world, it is necessary to pay close at- tures; 2) level of fiber backing material: different tention not only to quality, but also to productivity, types of commercial fiber with high ballistic perfor- which is the other competitive determinant in external mance will be tested, with the proposed innovation markets. In order to do this, it is important to incor- of testing the efficiency of the use of mixtures of la- porate in the production process all the technology- yers of different fibers; and 3) adhesive level: diffe- based knowledge available in the national academic rent polymeric adhesives will be tested, which im- environment. Within the sterilization process, produc- plies the optimization of the lamination process in tivity is determined by the speed of filling the pots the autoclave. The second phase of the work will in- with medium, by the volume of medium sterilized per volve the design and development of the products, cycle, by its cost, by the reliability of the sterilization that’s to say, the optimization in terms of materials process, by the amount of man-hours involved, by the and geometry. training of this manpower and by the quality of the sterilizing machine. Of these, the fundamental factors are the quality of the sterilizing machine and the relia- Study of the Technical bility of the sterilization process (absence of fungi and 367 Viability of the Use in Yoghurt of bacteria in the medium), in addition to the volume of Natural Beetroot Coloring Obtained production, in case of large orders. This proposal aims by Alcoholic Precipitation to study the viability of building a medium steriliza- (a New Methodology of Production) tion machine with plasma in replacement for the au- toclaving process. The equipment should use less elec- Coordinator: trical energy and, due to its automation, use less Rogério Côrte Sassonia specialized manpower, sterilizing according to the rate of consumption (just-in-time system) and not in large Company: pre-determined volumes. Clarear Consultoria para Indústria Alimentícia S/C Ltda. Approved value: Development of High Performance Phase 1: R$ 37,100 366 Laminated Armor Materials Composed of Alumina Ceramic and Fiber Fabric In this project it is intended to study the techni- for Personal and Vehicular Ballistic cal viability of the application, in yoghurt, of bee- Protection to NIJ Ballistic Levels III and IV troot coloring obtained by alcoholic precipitation. The main advantage of this process, when compared Coordinator: to other technologies, is the greater concentration of Ricardo Guimarães Morrone betanine in the product. Betanine is the substance

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responsible for the tinctorial power of the coloring, analysis of scenarios and identification of organi- capable of replacing with considerable advantage the zational strengths and weaknesses; 2) processes of commercial beetroot colorings currently on the converting knowledge from tacit to explicit (and vice- market. In addition, this substance has great poten- versa), such as socialization, externalization, interna- tial to replace synthetic colorings, which have been tionalization and combination; and 3) stages in the the subject of successive restrictions at home and learning process, such as concrete experience, reflec- abroad. Among applications of beetroot coloring, tion on what has been lived through, the shaping of recent studies (J. Agric. Food Chem., 2003) show concepts and the application of what is learned to that betanine displays good stability in the produc- new situations, taking as reference the model develo- tion and storage conditions of yoghurt, that is, pH ped by David Kolb. These business processes and between 4 and 5 and storage temperature of 40ºC. learning models will be integrated in a practical Furthermore, amongst the products of fermented form and in language accessible to the users. milk, yoghurt is without doubt the most widely con- sumed. To make viable the application of this colo- ring in the yoghurt manufacturing process, it must 18th BIDDING INSTRUCTIONS be confirmed that it does not compromise the fer- mentation process nor the viability of the lactic mi- croorganisms during their useful life. The color of Machine for the product must remain stable during the storage 369 Polishing Fiber period and, besides this, the addition of the coloring Optic Connectors should not compromise its taste. Complementary analyses will have to be undertaken to confirm the Coordinator: quality standards established by the Adolfo Lutz Ins- Benjamin Grossman titute, as well as to determine the sugar composition Company: with a view, also, to its application in dietetic products. Cromática Sistemas de Comunicação de Dados e Informática Ltda. Software for the Approved value: 368 Strategic Management Phase 1: R$ 22,400 of Knowledge On the international market there are some ma- Coordinator: nufacturers of machines for polishing fiber optic Valter Francisco Arruda Alves connectors. These items of equipment, which typi- Company: cally polish from 6 to 12 connectors simultaneously, Invenire Internacional Informática S/C Ltda. are extremely expensive as they are based on a very precise mechanical construction. In these machines, Approved value: the polishing film rests on a platen which moves in Phase 1: R$ 63,825 the form of a figure eight or planetary figure (for the combination of the two movements). In the project The objective of this project is to demonstrate proposed here, the objective is to develop a new type the viability of producing a piece of software for the of machine, extremely compact, the platform of strategic management of knowledge within an edu- which will execute a random vibratory movement, cational and entrepreneurial philosophy. There are similar to Brownian movement, although in ma- on the market costly software programs used in the croscopic amplitudes. Proceeding in this manner, management of knowledge centered on information the optimal characteristics of the fiber connectors technology, on management information systems, are achieved naturally, without the need for preci- or on the creation of corporate portals. None of the- sion in the mechanical make-up of the parts. As far se products takes as its starting point company stra- as is known, this idea is unique and the machine tegies and the knowledge conversion process, that is, should be the object of an international patent. De- the creation, the codification, the storing, the diffu- pending on the results to be achieved, this same pro- sion and the application of knowledge. The software posal could, eventually, be extended in three dimen- proposed here could be characterized as a learning sions, simulating a Brownian agitator aimed at resource. This product will make available, in the homogenizing mixtures for application in the che- form of templates, conceptual maps, texts and case mical, pharmaceutical or biological business. studies: 1) models for strategic management, such as

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Integrated Telemetric and Approved value: 370 Telecommand Solution Based on Phase 1: R$ 66,808 Wireless Technology for Refinement to Urban Services For the beauty of its song, the wild rice finch (Oryzoborus angolensis) is the bird which enjoys the Coordinator: best organized breeding in captivity in Brazil. The Antonio da Silva Jucá Junior rice finch appears on the list of the Brazilian Institu- te for the Environment and of Renewable Natural Company: Resources (Ibama) as one of the species commonly Gwyddion Indústria de Produtos Eletrônicos Ltda. confiscated in the traffic of wild animals throughout Approved value: Brazil. The activities of passerine breeders from Bra- Phase 1: R$ 61,948 zilian wild fauna are coordinated by Ibama, which recently developed a computerized system, Sispass, Advances in embedded computer technology for the registration of breeders and birds. Since have brought about the technical and economic via- 2001, 74 thousand breeders have already been regis- bility of the spread of microprocessed control sys- tered and almost 1.3 million birds, the majority rice tems, which today constitute a common resource in finches (245,085 birds registered). Sispass relies hea- all kinds of electronic equipment. The inclusion of vily on the truthfulness of the information supplied, communications facilities in these devices enables re- frauds being therefore a possibility. The proposal of mote access to their functions, creating conditions this project is to develop a system of genotyping of for the implementation of telemetric and telecom- micro-satellites of the rice finch, suitable for the mand systems. Amongst the benefits sought, are the computerized registration of the birds and the auto- reduction in operating costs and the improvement of matic parental determination (certification of ori- the quality of service by means of online monitoring, gin). The project could also cater for the recently an increase in efficiency in the use of shared resour- created Consortium for the Export of Native Brazi- ces, better integration with management systems and lian Birds, established by the National Cooperative decision support, refinement to security and new ap- of Native Bird Breeders (Cocpan) and the Brazilian plications enabled through inter-device interaction. Service in Support of Micro and Small Businesses Focusing on the potential of this technology, this (Sebrae), which relies on proof of guarantee of the project aims to put into action a research plan aimed origin of birds for the purposes of certification and at setting up an integrated telemetric and telecom- to be able to place the rice finch on the international mand system based on wireless communication via market, which would lead to the promotion of a new the mobile phone network. Exploring the most up- sector in the national economy. The system could be to-date telecommunications and internet technolo- adapted for various species of the Emberizidae fa- gies, the mechanism was conceived to operate on the mily, also bred in captivity, and, in some cases, threa- standard GSM cell channel, using the GPRS protocol tened with extinction. (GPRS is designed for applications which require te- lemetric and telecommand systems with mobility and reliable continuous flow of information). The Planning Tool for applications envisaged include sectors such as public 372 Broadband Data Transmission services, logistical control, patrimonial security, do- Systems Via the Electricity mestic billing, environmental monitoring and the te- Network Infrastructure lemaintenance of equipment. Coordinator: Carlos Alberto Fróes Lima Development of an Company: 371 Identification System for the KNBS - Telecomunicações e Informática Ltda. Rice Finch (Oryzoborus angolensis) Using DNA Microsatellites Approved value: Phase 1: R$ 7,000 Coordinator: Antonio Francisco Ferreira Neto This project aims to develop a tool for planning broadband data transmission systems via the electri- Company: city network infrastructure, using Power Line Com- Unigen Tecnologia do DNA Ltda. munication (PLC) technology. This tool should per-

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mit the design of broadband systems, from the so-cal- ted by electricity or infrared) on which saucepans or led last inch (internal network in the user’s environ- the food itself is placed. These plates have enormous ment), passing through the first or last mile, up to the esthetic appeal and are easy to clean with a damp backbone operator. The software tool to be developed cloth. In this work, it is proposed to develop, for use will be integrated with a relational database and to a in electric ovens, VC plates obtained through the georeferenced tool for the planning of access net- glass sinterization method which develops crystalli- works to broadband internet. In phase 1 of this pro- ne phases with a low coefficient of thermic expan- ject, focused on the preliminary study and in the set- sion. Extensive searches of national and internatio- ting up of the system, there will be a need to analyze, nal patent records were carried out, but failed to among other things: the parameters of the signal-noi- uncover any vitroceramic with applications in ovens se relationship, interference, bandwidth frequencies, with the characteristics described. transmission power and signal attenuation along the distribution lines in accordance with the topology. The noise characteristics of low and medium voltage Manufacture of Hospital distribution lines and their influence on the perfor- 374 Washing Machines and mance of PLC system will be evaluated. The system’s Consultancy to Hospital Laundries architecture will be totally object-oriented and the de- velopment environment will preferably be based on Coordinator: the use of open source software. PLC technology Choyu Otani could help in meeting the challenges of broadband in- Company: ternet access in Brazil, including the inclusion of di- Ecowash Ind. de Máquinas e Lavar Roupas e Servi- sadvantaged layers of society by means of the provi- ços Ltda. sion of services in areas and segments as yet uncatered for by networks and telecommunications services. Approved value: Phase 2: R$ 247,397 / US$ 16,585

Vitroceramics for Use in The aim of this proposal is to extend and deepen Electric Oven Plates the knowledge acquired in the previous project fi- 373 nanced by FAPESP, entitled Development of a High Performance Ozone Generator. During its imple- Coordinator: mentation, good results were obtained with the use Catia Fredericci of ozone in the process of washing hospital linen. Company: The current project aims to harness the necessary Vitrovita Instituto de Inovação em Vitrocerâmicos scientific and technological support in order to en- Approved value: dorse the process of the ozone-assisted laundering of Phase 1: R$ 38,896 / US$ 9,970 hospital linen, thus opening the way to achieving the Phase 2: R$102,310 / US$ 104,145.33 most relevant specific objective, which is the buil- ding and ratification of a new washing machine, cal- The production of vitroceramics (VC) is very li- led the EW 100, which will be integrated with an mited to traditional techniques of fusion, conforma- ozone generator. To be able to achieve these objecti- tion, nucleation (induced by the addition of cataly- ves, the company’s researchers and technicians will zers) followed by the growth of crystals in the pool the necessary multidisciplinary knowledge and volume of monolithic glass components. An alterna- experience for: 1) production of ozone generators; tive route for the production of vitroceramics is sin- 2) production of hospital washing machines; and 3) terization with controlled crystallization. In this Development of innovations in hospital laundry case, there is no need to add nucleation agents to the processes. Both the process and the machine should glass, given that particles of impurities and defects incorporate technological innovations. present in the very surface of the vitreous particles carry out the function of nucleation agent. The sin- Therapeutic terization should occur at the start of the process Vaccine for and only at the end should the crystallization be 375 Equine Melanoma commenced. These materials are useful in countless applications, such as in the surface of modern elec- Coordinator: tric ovens, which have no flame, merely circles (hea- Cristina de Oliveira Massoco

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Company: tributed components, design standards and frame- Oncocell Biotecnologia Ltda. works. The defined architecture allows for the tech- nological evolution of the rebuilt systems, since it Approved value: improves the quality of the code, makes future Phase 1: R$ 44,919 / US$ 7,161.11 maintenance easier and permits the running of the- se systems on heterogeneous, distributed and open According to the Brazilian Institute of Geo- platforms. The Catalysis method is used in the deve- graphy and Statistics (IBGE), the equine population lopment of the components; the principal mecha- in Brazil is around 6 million, of which it is estimated nisms for executing this approach are a transforma- that between 180 and 480 thousand suffer from me- tion system, a support tool for reverse engineering lanoma, which leads to a considerable economic and and a Case tool. genetic loss in the farming market. Melanoma is par- ticularly common in horses with dapple-gray pelage, after the age of five. Current treatments are based on Microcamera the application of chemotherapies, immunomodu- 377 Attached to Frontal lators and/or surgical resections which present a Surgical Illuminator high level of toxicity, iatrogeny and low effectiveness. The use of hybrid dendritic-tumor cell vaccines in Coordinator: human patients carrying melanoma and carcinoma Edson Minoru Kubo of the renal cells showed promising results. In view of this, the present project aims to verify the effi- Company: ciency of the same methods for equine tumors. The Foco do Brasil Indústria e Comércio effectiveness of the use of a variant of immunothe- de Aparelhos Científicos Ltda. rapy which will use hybrid cells generated by the fu- Approved value: sion in vivo of tumor cells with differentiated equine Phase 2: R$ 180,255 / US$ 9,285.25 dendritic cells will be analyzed. This project intends to use, in an unprecedented manner, the dendritic The objective of the project is to develop a mi- cells drawn from the equine peritoneal cavity in the crocamera attached to a frontal surgical illumina- preparation of an anti-tumor vaccine. If the attempt tor, the principal applications for which are aimed is successful, it will have produced an efficient the- at technical-surgical specialties and skills: heart rapy for equine melanoma and a new way of produ- surgery, neuro- and plastic surgery, among others. cing dendritic cells. The visual capture could even be used for the de- monstration of new techniques in scientific mee- tings; as a teaching tool in medicine and biology; Re-engineering of Large Scale for the live demonstration of procedures and ana- 376 Legacy Systems Based on tomy classes. The illuminator proposed here is wi- Frameworks, Distributed thout equal, offering superior technological innova- Components and Design Standards tions such as the complete elimination of parallax errors between the optical illumination system and Coordinator: the microcamera. In the first phase of the project, Edimilson Ricardo Azevedo Novais two prototypes were manufactured. Phase 2 aims to Company: make the technique developed even more sophisti- Transformare Evolução cated, to define the production process in accor- Tecnológica de Sistemas Ltda. dance with regulatory norms and to significantly reduce production costs. As far as commercializa- Approved value: tion is concerned, the dimensions of the Brazilian Phase 2: R$ 126,000 market are quite respectable. There are 45,500 sur- geons with technical skills and specialties, and This research project offers an approach to tech- other potential dimensions. The exploitation of nological evolution to rebuild legacy systems with specific niches and the launching of models with recurring bases and on a large scale, aiming to meet better technical resources and incorporating new the growing demand from businesses and govern- technological functions lifts the product into a con- ments that need to upgrade their software and hard- text in which expectations are very promising. It is ware platforms. This approach was structured on a estimated that the price of the equipment will be 50 robust software architecture base consisting of dis- per cent lower than imported equivalents.

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Sinterized te principally homopolymers and copolymers such 378 Vitroceramics for as, poly (L-lactic acid), PLLA, poly(glycolic acid) Ceramic Claddings PGA, polycaprolactone, PCL, poly(p-dioxanone), PDS. The results obtained facilitated the introduc- Coordinator: tion of various absorbable devices on the market, the Eduardo Belllini Ferreira first of which was sutures. Later, advances permitted the commercialization of polymers with sufficient Company: resistance for orthopedic applications. Nowadays, Vitrovita Instituto de Inovação em Vitrocerâmicos the greatest interest is focused on the synthesis of the Approved value: copolymer of L-lactic acid and of D,L lactic acid, ge- Phase 1: R$ 62,750 / US$ 1,350 nerating a completely amorphous and more flexible polymer which can be shaped by means of a hot Sinterized vitroceramics for ceramic claddings bath at the time of the implant, according to the pa- with a high esthetic appeal are commercially manu- tient’s anatomy. The aim of this project is to synthe- factured by a single company in the world, the Japa- size the copolymer PL-DLA, poly(L-lactic acid-co- nese firm Nippon Electric Glass (NEG). The main D,L-lactic acid). In order to do this, phase 1 of the commercial vitroceramic product for cladding is project involves two stages. The first involves the composed of the pseudo-wollastonita crystalline synthesis and characterization of the copolymer; phase, an acclaimed success, but of restricted use and the second stage involves pilot tests of proces- owing to the high price. Currently we are witnessing sing the polymer in the form of sheets and screws. a wild international chase after new compositions of Since the devices existing on the market today are sinterized vitroceramic with a more accessible price, imported, which restricts their consumption, it is with impact equivalent to that of porcelained gres, in hoped with this development to extend the use of applications such as floor and wall claddings, in ad- surgical implants to broader layers of the population. dition to many others. The intention of this project is to develop a material for use in ceramic claddings obtained by the sinterization and crystallization of Econometric Modeling glass particle compacts. Its main phase should differ 380 Project for the Broadening of from that used by NEG, namely, a complex pyroxe- Knowledge of the Brazilian ne of calcium, magnesium, silicon and aluminum, Geoinformation Market which displays promising properties for the applica- tions mentioned, such as extreme hardness, resistan- Coordinator: ce to abrasions and chemical resistance. Despite the Gilberto Câmara Neto technological advance in processes for the manufac- Company: ture of sinterized vitroceramics, the technique is still Geoconsult Ltda. far from saturation and is open to alternative proces- ses and formulations. Approved value: Phase 1: R$ 11,132 / US$ 4,150

Synthesis and Production of Poly This project aims to carry out the econometric 379 (L-lactic acid-co-D,L-lactic acid) modeling of the geoinformation sector in Brazil and Implant Materials develop a sectoral index to assist in the tracking of dynamics in this market. To support the creation of Coordinator: this growth indicator, it is intended to implement an Eliana Aparecida de Rezende Duek application for the exchange of metadata on geogra- phical information. Based on open source software, Company: the application will permit the dissemination via in- Engimplan - Engenharia de Implantes Indústria e ternet, of the location of georeferenced data bases, Comércio their origins and main characteristics, the identity of Approved value: their respective owners or patent holders for all the Phase 1: R$ 59,047 / US$ 2,400 available products, freely available or subject to commercial conditions, across the national territory. Since 1960, studies have been carried out to as- In phase 1, the proposal is to outline the methodo- sess the feasibility of various bioabsorbable poly- logy for a market research, as well as the way in mers for use in surgical implants. The studies indica- which the data obtained will be tabulated for use in

Translating Research into Business • 235 econometric models. It is also intended to describe This project aims to develop a prototype tele- the design for the application for the exchange of geo- phone receiver aimed at individuals who suffer from graphical information and the competitive intelli- light to moderate hearing deficits. This device gence system contained within the scope of this pro- should incorporate the means of digitally processing ject. In addition, still within this phase, in a business the voice signal received, in order to improve its in- plan, commercial approaches will be outlined, based telligibility. The equipment should allow the user to on suitable strategies for the information assets. control the application of the processing resources so as to adjust the result to the individual characte- ristics of his auditive perception. In this equipment GP-101 it is proposed to use signal processing algorithms 381 which are innovative compared to those usually found in conventional auditive prostheses, or even Coordinator: in ordinary amplified telephones; and which should Guido Fontegalante Pessotti be particularly suited to the characteristics of the te- lephone channel, such as: filtering with continuously Company: adjustable cut-off frequency, selective compression GP Aeroespace Ltda. of the dynamic range, spectral replication and trans- Approved value: lation. The evaluation of the effectiveness of the im- Phase 1: R$ 51,800 plemented processes with regard to intelligibility will be carried out by means of recognition tests of The project will study the viability and proof of isolated syllables and sentences applied on represen- concept for the development of a family of advanced, tative groups of different classes of hearing deficit. low cost and high performance aircraft, both man- ned and unmanned. These aircraft should be used in several sectors. In agriculture for the spraying of de- Development of a New System fensives necessary for the maintenance and optimiza- 383 of Multichannel Acquisition for tion of crops, mainly grain and sugar cane; in trans- Pulmonary Monitor Based on port, designed for distances above 1600 km and a Electrical Impedance Tomography velocity of 300 km/h; in the training of pilots; and in other paramilitary applications such as security and Coordinator: patrolling. The equipment should have considerable Harki Tanaka efficiency, economy and innovatory differentials Company: compared with existing aircraft. The plane will incor- Timpel S/A porate the most advanced aerospace technology and its nationalization index will be practically total. Approved value: With this logistics, the idea is to position Brazil as the Phase 2: R$ 299,611.07 largest global manufacturer of advanced and multi- functional ultralights, as well as to initiate advanced Over the last ten years various lines of research studies for the pioneering production, in Latin Ame- have been developed in the use of electrical impe- rica, of Unmanned Aerial Vehicles (UAVs). dance tomography (EIT) as a non-invasive piece of equipment for obtaining images of the human body recorded by electric current instead of X-rays. Ho- Development of a Telephone wever, to-date there is no equipment approved for 382 Terminal with Compensation use with patients for the monitoring of mechani- for Hearing Deficiencies cally ventilated lungs. This type of use is a new idea, still in the research and development phase, in Bra- Coordinator: zil as well as abroad. A EIT prototype was set up in Guido Stolfi 2003, as part of a thematic project financed by FA- PESP, with components existing on the market - Company: many of them imported and expensive. It is neces- Koller e Sindicic Importação e Exportação Ltda. sary for this prototype to evolve to the point of ob- Approved value: taining a better quality image, adaptation for use Phase 1: R$ 51,000 with human beings and for large scale industrializa- tion. To do this, a new system of signal acquisition and pre-processing for the measurement of bioim-

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pedance called Multichannel Acquisition System Company: (MAS) will need to be developed. This system will Central Brasileira de Comercialização e Distribui- permit an increase in the speed of image generation ção de Rã Ltda. and quality, the miniaturization of the interface Approved value: with the patient and a decrease in the cost of the ap- Phase 1: R$ 47,545.73 paratus. This entails a decisive step in the adapta- tion of the EIT at the bedside, as well as its financial The popular use of the oil extracted from the viability, making its costs competitive. fatty body of the Rana catesbeiana Shaw frog has in- creased, above all as an anti-inflammatory anti-ulce- rant gastro-duodenal cicatrizant. These bodies, the Recycling of Plastic oil of which is very simple to extract, are a waste ma- Bottles at Gas Stations 384 terial in abattoirs, therefore their cost is zero. The in- and the Like cidence of the pathologies mentioned has grown at an average 10 per cent a year and, amongst the most Coordinator: widely sold medicines to combat them, anti-inflam- Ivan da Cruz matory anti-ulcerants account for 31 per cent of the Company: world market. In addition to being expensive, the Compacto Ind. Com. Reciclagem Plástica - ME available medicines have some limitations in clinical Approved value: use and certain precautions need to be exercised in Phase 1: R$ 18,527 their administration. Since the scientific literature makes no reference to studies in this area, the pre- Gas stations discard into the environment plastic sent project proposes to carry out a pharmacologi- bottles of high density polyethylene (PEAD) contami- cal, toxicological, and chemical screening, involving nated with lubricant oil and additives used in the the evaluation of the anti-inflammatory activity of maintenance of motor vehicles. Since the biodegrada- the oil from that Rana catesbeiana Shaw frog species ble time span of PEAD is very long (over 100 years), applied topically and administered orally. The data these bottles reduce the useful life span of rubbish obtained will be compared to that of standard drugs dumps and landfills. The residual oil contained in the in four experimental models, two severe and two bottles causes soil pollution, as well as complicating sub-chronic, determining the dose-effect relations- the recycling process. Recyclers are discouraged from hip and calculating the effective dose. It is also inten- processing these bottles because there is no available ded to evaluate the anti gastric ulcer effect, compa- decontamination procedure. Based on these prece- red to standard drugs, in two rigorous experimental dents, the present project aims to study and develop models, determining the index of lesions, the para- recovery and recycling processes for lubricating oil, meters of gastric secretion and the establishment of additives and PEAD, originating in the leftover bottles the effective dose, amongst various other activities. in gas stations. The project has the relevant techni- The project also includes, at the end of this phase, ques for the creation of a piece of equipment called the chemical-analytical characterization and stan- the Chemical Decontamination Phase, which is al- dardization of the initial sample to be evaluated. ready in the secrecy phase with the National Institute for Industrial Patents (INPI). This equipment should carry out the extraction/separation of the lubricating Applied Oceanic oil contained in the plastic bottles, which subse- 386 Monitoring System quently will go on to be refined. The final stage will result in a viable global program to return these resi- Coordinator : dual pollutants to useful life, with extremely positive José Edson Rodrigues Pereira gains in environmental, economic and social gains. Company: Applied Science Consultoria Ltda.

Pharmacology, Toxicology and Che- Approved value: 385 mistry of the Oil Extracted from Fatty Phase 1: R$ 12,000 Bodies of the Rana catesbeiana (Shaw) The company has formed a partnerships with the Coordinator: Laboratory for Oceanic Numeric Modeling of the Jayme Antônio Aboin Sertié University of São Paulo’s Oceanographic Institute

Translating Research into Business • 237 with the objective of meeting the requests of Petro- ject are: 1) the use of record linkage to establish a bras for the development of oceanic current diagno- permanent master patient index; 2) the joint use of ses and studies of the impact of petroleum accidents the two technologies; 3) the adaptation of these in 21 of its terminals. From this association emerged technologies to the Brazilian reality; 4) the use of the basic tools and ideas behind the present project, methodological innovations such as nebulous logic which entails the development of a management and graph theory in record linkage; and 5) research system for the prediction of the drift of oil slicks, into a robust and scalable architecture capable of combining mathematical sophistication, practicality processing all the databases in the Ministry of and reliability of results for use in the case of acci- Health (a few terabytes). The planning for phase 1 of dent in a particular oceanic region. This system seeks the project includes, among other activities, conclu- to coordinate, in an optimized manner, hydrodyna- ding the specification of the system modules; speci- mic models of known formulation and applicability fication of the principal algorithms; specification of in the academic environment and models developed the data storage; the implementation of a complete specifically for studies of dispersion of oil, of chemi- prototype with all the modules. cal products, of the transport of sediment and of wa- ter quality. The technological innovations of this project should appear in small and multiple routines Development of a Support System which enable the setting up of a structure for auto- 388 for the Integrated Management mated environmental monitoring, providing quick of Pay-as-you-Fish businesses responses in complex oceanic environments, in in the Central Region of the terms of situational diagnosis and outlook. Imple- State of São Paulo – Fishing Project mented in a specific region, this system should be ca- pable of handling the management of observational Coordinator: data, meteorological forecasts and oceanic norms in José Galizia Tundisi different scales and resolutions. Company: Instituto Internacional de Ecologia São Carlos Ltda. Development of a piece of 387 Software for Pairing and Integration Approved value: of Personal and Health Phase 1: R$ 58,715 Information, Using Record Linkage Method and HL-7 Standardization The global aim of this project is to develop and apply a new methodology of diagnostics and impro- Coordinator: vements for fishing enterprises in the central region José Augusto Vasconcellos Neto of the state of São Paulo. The methodology centers on the quality of the water where aquaculture is prac- Company: ticed and in the socio-environmental improvement IPS - Informação e Planejamento em Saúde Asses- of the amenities and the whole operational system of soria e Comércio Ltda. the fishing grounds. It is intended to achieve this aim Approved value: by making available a digital data base, giving direct Phase 1: R$ 18,300 guidance on the implementation of necessary envi- ronmental improvements for bringing the enterprise The aim of this project is the construction of a up to standard. A piece of software will be developed system which administers customer subscription re- containing the self-diagnosis methodology and a cords, establishing a correlation (or pairing) bet- roadmap for the implementation of the necessary ween two or more subscriptions of the same person environmental improvements. The aim is for the using record linkage techniques. The correlated broad commercialization of this product with com- subscriptions may originate in the same or different petitive gains for the company and the exploitation databases. In addition to this, the system integrates of the activity within high quality parameters. It is the health information originating in the different also intended to assemble kits for analyzing the water data bases using the HL7 protocol. Thus, the project quality which should be available to the fish farmers is based on two technologies (record linkage and and be used by their own employees, following trai- HL7) which, although not exactly new, are to a cer- ning. It is planned to train a large number of dissemi- tain extent still experimental and not very well nating agents and instructors so that they can do the known in Brazil. The innovative aspects of this pro- training of technical and administrative personnel,

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so as to provide continuity to the improvements and Approved value: watch over the evolution of the environmental ma- Phase 1: R$ 61,600 nagement systems developed in the fishing grounds. Natural rubber latex obtained from the tapping of trees is anionic by nature, being traditionally used Precision System in this form for the production of gloves, condoms, 389 for the Localized adhesives and foams, among other materials. The Variable Rate stability of latex is short, due to the action of mi- Limestone Application croorganisms which reduce the pH, destabilizing it and promoting its spontaneous coagulation. There- Coordinator: fore, the addition of preservatives such as ammonia Luiz Antonio Balastreire is necessary to increase its stability and permit its use Company: in the form of aqueous dispersion. Although the Enalta Inovações Tecnológicas para Agricultura production of latex has been increasing in the coun- try, there is still a great dependency on imports. This Approved value: project aims to develop a new methodology which Phase 1: R$ 76,789 makes it possible to obtain cationic latex from natu- ral rubber on a commercial scale. The preparation of Agricultural correctives are fundamental inputs in this new raw material entails the collection, the ad- farming. The efficiency of the production process de- dition of anticoagulant agents and diluted acid, to pends on the quality of these inputs and the way in give a latex with a pH of around 4.5. The entire pro- which they are applied to the soil. When there are fai- cess of adding anticoagulants and acids should take lures in their use, this stage is compromised, creating place in the farm where it is produced. Different an- results which directly affect agricultural productivity. ticoagulants will be researched, in different propor- Creative and innovative solutions in this area have tions. Subsequently, the treated latex will be centri- been the subject of research into the development of fuged to determine the pH, the level of solids, new products, owing to the demands for a reduction particle size, zeta potential, colloidal stability, visco- in costs, a decrease in environmental contamination sity and mechanical properties such as resistance to and an increase in the efficiency in the application of traction, stretching and elastic return. These results correctives and fertilizers. The project proposed here will enable the evaluation of quality and the viability aims to meet the needs of the farming market by of producing the product on a commercial scale. means of the development of an innovative system geared towards the localized application of correctives. This system will be integrated to work in inhospitable Integrated System for the Obtaining field conditions and to be operationally viable within of Georeferenced Information for the the dynamism of the activities encountered, so as to 391 Dynamic Control of Water Quality establish a new management concept in this sector. Basically, the system will consist of an item of equip- Coordinator: ment for the distribution of correctives and fertilizers, Maria Nogueira Marques through a central processing and data collection mo- dule, through a CAN scan and specific geographical Company: information software for precision agriculture. Nexus Geoengenharia e Comércio Ltda. Approved value: Phase 1: R$ 73,120 Development of a Methodology 390 Applicable for the Production of The objective of this project is to obtain systema- Cationic Latex from Natural tized information on distributed water quality. In Rubber on a Commercial Scale order to do this, the monitoring of the distributed water quality performance will be studied in the Coordinator: form of quality indices, remote transmission of data Márcia Maria Rippel and the generation of thematic maps. The choice of Company: index should, among other factors, address and Prolatex Comércio de Latex Ltda. check standards of potability; identify possible ano- (ex-Estância Santa Terezinha) malies in the variable or group of variables; offer fle-

Translating Research into Business • 239 xibility in meeting new parameters or legal require- Company: ments, allowing for the inclusion or exclusion of pa- Ecozon Ind. Com. Imp. e Exp. de rameters, once they are appropriately evaluated and Equipamentos Geradores de Ozônio Ltda. calibrated; offer flexible periodicity (daily, weekly, Approved value: monthly or six-monthly). The remote station will be Phase 1: R$ 74,523 equipped with an alarm system for anomalies. This entails the development of a piece of equip- Novogesso ment to generate ozone by corona discharge with a capacity to generate 30 grams of gas per hour, in a 392 single cell. Internally this cell contains several elec- Coordinator: trodes, encapsulated in stainless steel tubes, bundled Milton Ferreira de Souza in bee-hive form, through which pure oxygen or compressed air circulates. During the passage of the Company: air or oxygen through these tubes, the electrode is Inovamat - Inovação em Materiais Ltda. activated by a high voltage electrical discharge, Approved value: which breaks the oxygen molecules apart, permit- Phase 1: R$ 74,370 ting the generation of ozone. The equipment will have a transformer, an inverter and a current induc- The project aims to demonstrate the technical tor, which will serve to control the corona discharge viability of the making of phosphoplaster boards within the cell. The generator will also have a micro- and molds, straight plaster and beta-phosphoplaster processed electronic system which will permit the mixtures through an innovative process. The follo- remote control and monitoring of all the functions wing stages are anticipated: 1) development of a de- of the apparatus. It will also have a safety system vice to dampen the hemihydrate powder in a conti- which will be capable of sending messages to a com- nuous form; 2) development of a compactor capable puter, cell phone or pager, in case of irregularities in of promoting the conformation and hardening of the system. This generator should allow adjustment the dampened hemihydrate into dihydrate (plaster to the quantity of ozone to be produced, between board); 3) comparison with results obtained with zero and the anticipated maximum of 30 grams per pieces compacted by a standard uniaxial press; 4) hour, being capable of adapting to different condi- submit to the National Institute for Industrial Pro- tions of use. The innovation in the project enhances perty (INPI) a patent request for the details of the the qualities of the equipment produced by Ecozon, process developed and also the equipment; 5) esta- the advantages of a cutting edge technology, which blish contact with phosphoplaster producers to as- should lead to a capacity to generate much more certain the safety aspects related to the use of this ozone at lower costs when compared to equivalent material or its association with beta plaster in civil imported products. construction; and 6) initiate contacts with parties potentially interested in the technology under deve- lopment. The products obtained will be characteri- Production of Intervariety zed as for their mechanical properties (resistance to 394 Hybrids and Segregating compression, to bending and to impact) and poro- Populations of Gerbera jamesonil, sity. Dimensions will be studied that will permit the with Help from Molecular Biology use of the boards in partitions. At the end of the pro- Techniques, Aiming to Produce ject, the equipment will be used in the development New Commercial Cultivars of other products based on Portland cement, cellu- lose fiber and plaster composites, plaster-cement Coordinator: composites and thin cement boards. Monique Inês Segeren Company: ProClone Comércio de Mudas e Matrizes Ltda. Development of High 393 Capacity Oxygen Approved value: Generating Equipment Phase 1: R$ 39,500

Coordinator: In the floristry business, the variety of cut gerbe- Miqueas de Oliveira Braga ra daisies offers great commercial value due to their

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attractive coloring, size and format. There currently bed that was resting now receives the compressed exists on the producer market a wide variety of mo- air, and the one that was operating has its pressure dern gerbera cultivars obtained by means of genetic relieved so as to regenerate the zeolite and so on improvement. But these plants are imported, which successively. The oxygen which leaves the buffer leads to the high cost of the seedling (around a third tank is fed through to an analyzer which reveals the of the product’s final cost), in addition to dependen- level of purity obtained. A small part of the gas that ce on foreign companies. In this project, traditional leaves the buffer tank is diverted to assist in the re- improvement procedures by means of sexed cros- generation of the zeolite bed that is resting. The sings should be carried out. The parent plants will prototype should be built in such a way as to permit be identified by the molecular marker technique in the carrying out of experiments with three different which the gerbera cultivars that display the greatest sizes of adsorbent beds. genetic variety – leading to hybrids of greater strength – will have directed crossings. Seeds will be gathered, individually, after each crossing carried out. Conception and Development The intervariety hybrids obtained will be evaluated 396 of Prototype User Adaptable Interface according to the character of the flower (format and for Building Automation Systems coloration) and the plant (profiling potential, speed of regrowth after pruning, size and diameter of the Coordinator: stem and characteristics of post-harvest durability. Nelson Marinelli Filho Company: Development of Nelson Marinelli Filho - ME (Ethos Automação) 395 Oxygen Generating Approved value: Equipment Phase 1: R$ 45,450

Coordinator: The success of building automation systems for Nelson Antonio Félix Beirão the residential market and low footfall commercial Company: premises depends on two factors: the capability of Ecozon Ind. Com. Imp. e Exp. de Equipamentos Ge- the interface to adapt to the needs of the customer radores de Ozônio Ltda. and the suitability of the price for the market seg- ments they hope to reach. The proposal for techno- Approved value: logical development presented here is based on the Phase 1: R$ 73,929 need to create new user interfaces for building auto- mation systems. The stages of the project were defi- This project aims to develop a reliable low cost ned in accordance with the previous experience of piece of equipment, with national components, or the project coordinator in this market. In phase 1, which can easily be acquired on the national mar- the objective is to conceive and develop the require- ket. The proposal is based on a time-honored pro- ments for this interface up to the level of prototype. cess – selective adsorption under pressure – control- ling and regenerating the adsorbent element by means of a sophisticated electronic system. The fun- Tracking, Monitoring damental principle being exploited is that certain 397 and Debugging Tools for substances, zeolites, display the peculiarity of adsor- the VisualRT Development bing nitrogen when subjected to a pressure of 4 to 5 Visual Environment atmospheres. Once the pressure is relieved, the deabsorption of nitrogen occurs, restoring the zeo- Coordinator: lite to its initial condition. The idea is to build an Nilton César da Silva oxygen generator with the following physical arran- gement: two zeolite beds (molecular sieves) connec- Company: ted to a buffer tank. When the operation starts, Eonic Brasil Ltda. compressed air at around 5 atmospheres is forced Approved value: across one of the molecular sieve beds, which re- Phase 2: R$ 24,800 tains the nitrogen and lets the oxygen pass through, which continues on into the buffer tank. After a cer- The objective of the proposed work is the crea- tain period of time the two beds are inverted; the tion of two graphical tools to help the programmer

Translating Research into Business • 241 identify and correct errors which occurred in the generated, the costs of the main requisites for geome- implementation phase of real time systems. One tric trials should significantly decrease, allowing for tool will be responsible for the debugging and the increased offer of the quality control service in radio- other for the tracking and monitoring of applica- diagnostics and compliance with the legislation men- tions created by the user. They will be integrated tioned above. Furthermore, the procedural routine with the VisualRT visual environment created by will be optimized, streamlining the application of the Eonic Brasil to facilitate the development of real tests for the verification of the geometric parameters time applications which run on parallel machines of the X-ray equipment. In addition, the implemen- with high processing power. In addition to offering tation of new procedures for quality control will per- assistance in debugging programs, the tools referred mit savings on film, on hours with machine and to will provide, for experienced programmers as manpower on hold, with great impact on the reduc- well as beginners in parallel programming, the vi- tion of costs in the radiology sector. sualization of the mechanisms which control the synchronization, the communication and the task steps which make up a program. The addition of Improvement and Expansion these two tools to VisualRT will create an integrated 399 of Manufacturing Simulation and environment for the development of real time ap- Management and Factory Floor plications, offering support for every stage involved Supervision Software, for both in the implementation of these systems, from the the National and International Markets generation of source code to the test phases, debug- ging and analysis of performance. The economic Coordinator: viability of this environment is quite considerable Pedro Paulo Lanetzki because, currently there are few commercial softwa- Company: re products aimed specifically at the development of Netz Informática S/S Ltda. real time systems, an area where line commands or difficult to use tools still prevail. Approved value: Phase 1: R$ 72,535

Development of National The aim of this project is to enable improvements 398 Technology: Production and a new platform for the company’s solutions, so as of Integrated Devices for the to offer concepts, technological innovations and pro- Quality Control of Images cedures yet to be discovered in the areas of Manufac- in Radiodiagnostics Equipment turing Simulation and Management and Factory Floor Supervision. This new platform should enrich Coordinator: the solutions that exist today, enabling better com- Paulo Roberto Costa munication between industrial plants, their control Company: from a single location and access to the situation of Física Médica Serviços e each of them wherever they are, at any time, in real Consultoria Técnica S/C Ltda. time. The real time monitoring of crucial moments in processes and the alerting to any deviations that Approved value: might occur enables the immediate taking of mana- Phase 1: R$ 70,330 gement and/or corrective actions. The aim is to be able to act at the moment deviations are noticed and A decision by the Ministry of Health decrees that not merely be limited to reacting to the report of every establishment possessing radiodiagnostics what actually happened. The warnings could be gi- equipment should carry out, periodically, tests that ven in synoptic screens, on the machines themselves guarantee the quality of the images generated, as well and in luminous and/or sonic panels, among other as the minimum exposure to radiation for their users means. The commercial potential of this project is (patients and professionals). The aim of this project extremely broad, since its implementation will esta- is to prove the viability of the development of inte- blish Netz Informática in the segment of software de- grated simulator objects for quality control trials in velopers geared to industrial solutions and will per- diagnostic radiology (phantoms) and procedures mit the company to compete on equal terms which will make these trials faster and cheaper. With (technology and price) with similar foreign compa- these project aims achieved and national technology nies in the internal and external market.

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Development of a The project will undertake the development and 400 Computerized System prototyping of the Mercury module, a Hardware Se- for the Management of the curity Module (HSM) from Kryptus Tecnologias. Fish Production process Mercury will be able to provide advanced crypto- graphy services with a high performance and redu- Coordinator: ced cost piece of hardware for applications such as Ricardo Firetti electronic authentication and certification of data. The research project involves three main elements: Company: 1) the prototyping of the circuits; 2) the prototyping Sales e Macedo Assessoria Empresarial S/C Ltda. of protection against physical attacks; and 3) the Approved value: evaluation of a real random number generator. The Phase 1: R$ 50,070 prototypes of the circuits, which are at an advanced stage of design, will be implemented under the form The export of fish has shown itself to be an excel- of a cryptographic accelerator for PCI scans, using lent alternative outlet for Brazilian production. In reconfigurable high performance hardware (FPGAs this context, the United States, Canada, European with 130 to 90 nanometers technology) which, toge- Community and Japan are extremely demanding in ther with the on-board processors, will implement relation the origin of food products and their infor- the necessary cryptographic mechanisms. These me- mation systems, insisting in so-called traceability. chanisms, once implemented in VHDL, will be This project aims to outline a system that will assist adapted to function on the platform and evaluated in the management process of fish production, see- regarding their cost-performance relation. The pro- king to optimize the monitoring and control of dif- totyping of mechanical protection from physical at- ferent stages of breeding. This will also permit admi- tacks will involve the creation of elements which, at nistrators to visualize an array of information the same time, display the evidence and protect quickly and systematically, enabling the implemen- against attempts to alter the device. Random num- tation of genetic improvement programs and animal ber generators with real entropy sources will be built traceability. More than the creation of a simple com- and evaluated. The statistical analysis of results will puter program, this proposal aims to develop a ma- be carried out under trial attacks. nagement system that provides support for the con- trol of the activity and decision making. In the first phase, the aim of the research should be reached by: Development of Heat 1) Gathering of information (in loco), on the han- 402 Pumps for Residential and dling of ten different fish production systems; 2) De- Industrial Applications finition of the scope and logical functions of the sys- tem; 3) Analysis of software alternatives to support Coordinator: its development, in which it is intended to define the Rodrigo Aparecido Jordan system’s programming language with regard to its Company: use and possible expansion; and 4) Outline of the Thomson - Tecnologia em Energia Térmica e Bom- prototype, which consists in the formatting of the bas de Calor Ltda. product to be developed in the next stages. Approved value: Phase 1: R$ 31,807 Design of High 401 Performance Cryptography The present proposal is aimed at the develop- Module (HSM) ment of heat pumps for residential and industrial application, as well as hotels and agroindustry. Heat Coordinator: pumps are very efficient for use in heating air and Roberto Alves Gallo Filho water, being able to produce a thermic effect three to five times greater than the electrical energy used to Company: generate it. With an electric resistor, a commonly Kryptus Serviços Desenv.Tecnologias used device in Brazil, it would be difficult to achieve para a Segurança da Informação Ltda. a greater thermic effect. On the other hand, a refri- Approved value: gerator can also work as a heat pump. Thus, in the Phase 1: R$ 22,990 / US$ 5,393.93 case of applications in the home or in hotels, the

Translating Research into Business • 243 heat pump can, simultaneously, air-condition the Quantitative Genetic Evaluation rooms and heat water for baths, for use in the kit- 404 of Ostriches (Struthio camelus) chen and in the swimming pool. In this way, existing in the State of São Paulo refrigerating units can be adapted at relatively low cost to operate as heat pumps. In the first phase of Coordinator: this project, tests will be carried out on a water-wa- Rodrigo Possa Bertazzo ter prototype, developed by researchers from the Company: State University of Campinas (Unicamp) for use in Bianco Avestruz Ltda (ex-Brasil Ostrich) agroindustry. Given the characteristics of its cons- truction, it could even be used in other applications. Approved value: A prototype low cost heat pump for residences will Phase 1: R$ 43,876 also be assembled so as to carry out tests. Market niches based on breeding animals and products derived from the ostrich such as meat, lea- SuperVision: Support ther, eggs and feathers could be extremely interesting 403 System for Railway for Brazil. However, for production to be able to ca- Logistics and Operation ter for the growing demand it is necessary to integra- te the efforts of researchers, selectors, commercial Coordinator: breeders, the refrigeration industry and the govern- Rodrigo Almeida Gonçalves ment. The present project aims to generate research on the genetic quality of ostriches so as, subse- Company: quently, to implement in Brazil a program of genetic C-Flex Computação Flexível Aplicada Ltda. improvement for these birds and generate the neces- Approved value: sary genetic evaluations so that producers, from a di- Phase 1: R$ 58,160 gest of ostriches, can correctly choose the animals that will serve as reproducers in the future. The pro- The proposal aims to create a system that moni- ject includes the measurement of weight characteris- tors railway operations and offers input to assist in tics linked to the weight of birds at different ages; decision-making in either active or passive form. In reproductive characteristics to be studied, such as li- passive monitoring, the system observes, in real bido and number of eggs, among others; and patho- time, the essential variables to characterize the state logies such as navel infection and splayed legs. The of the operation (such as position of trains, number necessary genetic parameters for the prediction of of wagons in the yards, maintenance times, the con- heritability and genetic correlation, will be obtained dition of locomotives, among others) and detects si- by means of the use of the MTDFREML (Boldman e tuations of potential risk or damage, in the present Van Vleck, 1995) system. For the solution of mixed or future. The system then sends messages to the model equations, the ABTK (Golden et al., 1992) railway operators and supervisors, communicating and TKBLUP (Golden et al., 1995) software suite the occurrence of significant events so that, in good will be used. The Linux operating system should be time, they can make the relevant decisions and, the- adopted as well as SAS and FOX software for the ma- refore, avoid risks and damage. In active monito- nipulation and consistency of the database. ring, in addition to supervising the state of the net- work, yards, trains and traffic, the system helps in the supervision and control of traffic, assists in the Innovations planning and optimization of traffic on the net- 405 in pH and work, in the traffic logistics and multimodal opera- Conductivity Meters tion. SuperVision is a project with multiple objecti- ves and work fronts. To implement it in a Coordinator: monolithic manner would be very risky and costly. Santos Demetrio Miranda Borjas Thus, to control the risk, the quality and the cost, Company: the system was divided into six sub-projects, some Anatech Equipamentos de of which already implemented. The proposal now is Medição e Controle Ltda. to implement the rest of them so as to consolidate the SuperVision system. Approved value: Phase 1: R$ 68,680

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This research aims to develop a pH and conduc- ers. The alternatives currently used are based on tivity meter in a single device for use in the field (en- conventional servo-hydraulic systems, costly to ac- vironmental analysis) and laboratory. The choice of quire, install and operate. The device proposed in this project is based on the existing deficient techno- this project should be a very much simpler alternati- logy in the Brazilian market in the manufacture of ve, cheap, easy to install and operate. The system is this type of equipment and in the experience of the compact and uses as its power source the conventio- members of the team in analytical instrumentation. nal pneumatic line normally available in industrial Owing to environmental legislation, globalization plants. The design for the platform is in progress and current quality norms, there has been a growing and, in the course of the first phase, it is intended to increase in imports of these instruments. As a conse- build the device and carry out several experimental quence, in addition to the high cost of laboratorial tests for a detailed analysis of its technical viability. analyses, a deficit in the country’s trade balance has been noted in this segment. The equipment to be de- veloped should have an extremely accurate measu- On-Line ring system (1 per cent full-scale accuracy or better), 407 Sales Tool and the ability to store data with date and time of ac- quisition to generate reports on printers or compu- Coordinator: ter. The equipment should include innovations such Wagner Palmiere as automatic detection of more than one type of Company: temperature sensor; rechargeable batteries; recall of Siena Soluções Tecnológicas e Com. Ltda. last adjusted temperature value for pH manual com- pensation; and conductivity, in this respect, surpas- Approved value: sing imported models. The equipment will have Phase 1: R$ 35,016.31 guaranteed application in the chemical industry and principally, in laboratories and institutions engaged The objective of this project is to develop a sys- in environmental monitoring. tem which enables commercial transactions for pro- ducts directly at the point of sale. The solution should permit the remote generation of checks on Hydropneumatic customer registration; condition and availability of 406 Linear Position product stock; placing of orders; delivery confirma- Controller tion to the central base evolving from the sales ve- nue; generation and issue of receipt referring to all Coordinator: the transactions, with printing to be carried out on Sidney Nogueira Pereira de Jesus the delivery van through an on-board printer. The On Line Sales Tool system uses Java (J2EE) language Company: for the development of the application; Java (J2ME) Hydrex Comercial Hidráulica Ltda. for the development of the collector (PDAs) applica- Approved value: tions; GSM or CDMA technology for the remote in- Phase 1: R$ 45,200 tegration of the collectors with the application ser- ver; the MySQL server as database; Jboss on the The aim of this project is to develop a hydrop- application server; and Linux as operating system. neumatic linear position controller. The system is The ultimate expectation is to obtain a system that compact and contains in the same block a hydraulic runs remote real time/online communication with actuating piston, two pneumatic control actuators the central database, so as to carry out customer controlled by two pneumatic valves of the on-off checks and transactions, using for this purpose type, an electronic control system and a sensor to PDFAs and communication via GSM or GDMA. monitor the misalignment of the actuator and to ge- The possibility of implementing open source plat- nerate a signal to shut off the control network. The forms in the architectonic make-up of the solution idea is innovative and seeks to fill a need in the mar- will make possible a system the final price for which ket for precision linear positioning for small align- should consist merely of the license for the operatio- ments and heavy weights, such as the positioning of nal use of the application and the cost of customiza- cylinders in the lamination, paper and cellulose and tion and parameterization, which, it is hoped, will plastic films industries and valve opening control in lead to the popularization of the product. the petrochemical and food industries, among oth-

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19th BIDDING INSTRUCTIONS There has been a growing demand for silica-alu- minous and aluminous firebricks for medium and Development low duty applications in important industrial seg- 408 of Humidifier for ments. The small profit margin in current silica-alu- Fuel Cells minous bricks, for medium to low duty use, has li- mited their availability on the market, which obliges the user to use products of a higher aggregate value Coordinator: and, consequently, to end up with higher costs. In Angelo Massatoshi Ebesui the light of this, this project proposes, in its first pha- Company: se, a broad study to establish the production condi- Electrocell Ind. e Com. Ltda. tions of the firebricks of the classes mentioned, at low cost and of good quality. For its sole component, Approved value: what could be called chamotte should be used, Phase 1: R$ 39,800 which is produced at low temperature, and is then directly pressed and fired, giving the classes referred This project aims to study and develop a gas hu- to. This proposal is based on positive preliminary midifier for 5 kilowatt fuel cell which should offer tests which need to be more closely checked, under greater efficiency and durability to the cells’ polyme- the umbrella of normalized trials of a greater range ric membranes. Three different types of prototype of of possible compositions. The development of this a humidifier for 5Kw cells will be analyzed, built and technology should result in an important innova- tested, for subsequent selection of the winning tech- tion, considering that the immediate benefit from its nology. The following will be tested: 1) solid iono- implementation will involve the abolition of com- mer capillary tubes; 2) proton selective membrane mon stages in the conventional processing of refrac- associated with the cell; and 3) nebulizer and atomi- tory aggregates, such as chamotte pre-firing (1300- zer. The prototype with validated technology will be 1500ºC), its milling and granulometric separation. developed and refined for a fuel cell with 50 Kw po- The refractories to be produced by the proposed new wer (five 10 Kw modules), in the Aneel/Eletropaulo route will certainly offer a more homogeneous as- project, supported by FAPESP, which is in progress. pect and more uniform texture, retaining the attri- The expectation is that the development of this pro- butes of conventionally produced refractories, inten- posal will establish the technological consolidation ded for similar applications. of a complete package of the development of fuel cell with the application of the intelligent system concept. The validation of this development will Development of bring the company and the team involved the exper- 410 an Electronic Ear Tag for tise to commence scaled production, concomitantly Cattle Identification with the final fuel cell tests and trials. The cells to be produced should ultimately have a power of 50 Kw Coordinator: for use in residential buildings, industries, hospitals Carlos Gustavo de Camargo Ferraz Machado and schools, among other consumers. Company: Korth RFID Ltda. Production of Approved value: 409 Silica-Aluminous Fire Bricks Phase 1: R$ 81,900 with Chamotte Produced at Low Temperature The Ministry of Agriculture is implementing Sis- bov, a system which aims to identify, record and mo- Coordinator: nitor, individually, all the cattle and buffaloes born Arnaldo Carlos Morelli in Brazil or imported. According to the chronogram, Company: the entire national herd should be entered in the sys- Deflotec Indústria e Comércio tem by December 2007. Identification can be achie- de Produtos Refratários Ltda. ved by means of a conventional plastic ear tag, fire- brand or tattoo, which gives the user the animal’s Approved value: identification number or code. Electronic identifica- Phase 1: R$ 65,300

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tion systems record the animal’s number on a collec- ject is to respond to the laparoscopy equipment mar- tor together with data such as weight and vaccines. ket, which is growing, with a national product which The collector transfers the data to the computer is low cost and which has differentiated resources (PC) through a serial connection. The process is er- which will make it innovative and competitive. The ror free. The electronic ear tag is a management tool principal advantages of the product should be its which enables an improvement in the efficiency and portability, the integrated and easy to use control in- competitiveness in the rearing of slaughter or dairy terface, its resources for televideolaparoscopy (sha- cattle, pigs, sheep and goats. However, it is an expen- ring images in real time via local network and/or the sive system, which makes it unviable for the vast ma- internet), digital documentation, automatic lumino- jority of producers. The aim of this project is to de- sity control and its safety features. velop and train the company to manufacture, at low cost, this electronic identification ear tag. Its design entails the development of the transponder, which is Development of a Sugar an electronic device which retains a number in its 412 Cane Productivity Monitor to memory and, when activated by radio frequency, Obtain Productivity Maps for transmits the data to a receiver. This involves an in- Self-propelled Harvesters novative proposal by promoting the development of a technology held by few companies in the world. Coordinator: Domingos Guilherme Pellegrino Cerri Company: Research and Development Enalta Inovações Tecnológicas para Agricultura 411 of Microprocessed, Portable, and Low Cost Videolaparoscopy Equipment, Approved value: with Functions for Monitoring and Re- Phase 2: R$ 207,361 cording Vital Signs and Images Much of the research carried out in precision Coordinator: agriculture is concentrated on the development of Carlos Magno de Oliveira Valente corrective dosers and evaluators of yield for grain crops such as wheat and soya, which are products Company: cultivated in sub-tropical areas and predominantly Sensoft Comércio de Materiais para Informática, in developed countries. Thus, in this project the cul- Software, Consultoria e Treinamento Ltda. tivation of sugar cane was chosen because, in addi- Approved value: tion to being of great economic importance in Bra- Phase 1: R$ 84,170 zil, it has barely been explored by precision agriculture techniques. This project aims to instru- Carrying out abdominal surgery by laparoscopy ment a sugar cane harvester, so as to be able to ob- requires an insufflator, a piece of equipment respon- tain the productivity map for this crop. The system sible for distending the peritoneal cavity with CO2; to be refined is based on the productivity monitor an external light source, for illumination of the ca- designed, developed and patented by the State Uni- vity, which permits the visualization of the interior of versity of Campinas (Unicamp), with support from the abdomen; microcamera, responsible for the cap- FAPESP. The equipment uses weighing cells as an ture and projection of the image on a monitor; and instrument for determining the weight of the raw forceps, specific to the surgical procedure. The lapa- material harvested and will be capable of measuring roscopy equipment industry is virtually nonexistent the flow of stalks that pass over the belt before being in Brazil. Imported products have a very high cost thrown into the transporting vehicle. This data, to- and the tendency to be sold in modules. The present gether with the information obtained from a Diffe- lack of integration between the laparoscopy equip- rential Global Positioning System (DGPS) installed ment items means that the surgeon has to acquire va- in the harvester, permits the creation of a digital map rious systems which take up a large amount of space, which represents the production surface for the har- making their handling, control and transport diffi- vested area. This system will be tested in the labora- cult. In this context, the objective of the present pro- tory and in the field.

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Study of the In the chemical and food industries, the metal 413 Viability of the Development filter, normally produced by powder metallurgy, is of Software for Natural subjected to conditions which demand high mecha- Vulnerability to Pollution in nical resistance and, very often, high resistance to the Physical Environment corrosion at high temperatures. A material normally used is stainless steel, although nickel alloys can be Coordinator: an alternative. Both the chemical industry and the Fabio José Meaulo food industry import significant numbers of filters in tube form, tall (up to 1.10 meters), with a thin Company: wall (around 2mm.), known as cartridge filters, pre- Fortgeo - Geociências e Meio Ambiente Ltda. ferentially used because they offer an extensive filtra- Approved value: tion area and, therefore, permit greater discharges of Phase 1: R$ 42,678 filtered fluid. It is known that, for a specific type of application (herbicides), nickel (Ni200) cartridges The proposal presented here aims at developing are used and, in this case, problems of structural in- a piece of software for evaluating natural vulnerabi- tegrity have been observed. This project seeks to eva- lity to pollution in the physical environment which luate the production of stainless steel cartridge filters may contribute to decision making on the part of by the soldering and calendaring flat sheets. The the municipal public manager. This product is based sheets will be manufactured by two routes: uniaxial on knowledge of the geology and hydrogeology of compactation and vibration. The focus here is the the area where the municipality is located. In other manufacturing process and whatever is developed words, the software will assist in suitable strategies for stainless steel will work for nickel and other al- and actions for the different forms of human inter- loys. In this first phase of the project, the objective is vention in the physical environment. The develop- to arrive at a prototype which can be tested on the ment of the proposed computational program will equipment of a customer already contacted. This be formatted in a language compatible with the prototype will probably be produced by vibration, Windows environment, easy to use and of low ope- since there are dimensional limitations to the unia- rational cost. The Software information system is xial compactation process. segmented in three groups: 1) entry of data on the physical environment, sources of pollution, federal and state legislation and the valuation of real estate AbEvo - (Antibodies Evolution). in the municipality; 2) database generating system; 415 Intelligent System and 3) output of processed data in the form of re- for the Development of ports, graphs, and digital cartographic documents. Antibodies Based on the The final product of this project should be characte- Structure of the Antigen rized by its high potential for commercial and social return. The software for mapping natural vulnerabi- Coordinator: lity to pollution in the physical environment will be Humberto D´Muniz Pereira made available to teaching and research institutions Company: and small municipalities in the State of São Paulo Cientistas Associados, Comércio, Representação, Consultoria e Treinamento Ltda. Development Approved value: 414 of Cartridge Type Phase 1: R$ 82,480 Sinterized Metal Filters This project proposes the creation of a computa- Coordinator: tional tool for the development and optimization of Francisco Ambrózio Filho antibodies (AbEvo) driven by the structure of a given Company: antigen (in silica evolution). Inspired by the success- BRATS Indústria e Comércio de ful programs outlined for the planning of medicines, Produtos Metálicos Especiais Ltda. the tool aims at a reduction in cost, in development time and to facilitate the steps in the production of Approved value: antibodies. In its first phase, the project envisages the Phase 1: R$ 99,000 development and prevalidation of the tool which, in

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the second stage, will be fine tuned and validated. kinetic, the consumption of substrate and the pro- Among the advantages expected from antibodies duction of rhFSH and metabolites under different conceived using this methodology, the most outstan- conditions in order to establish the most efficient ding is the prevention of hypersensitive reactions process for the culturing and production of the bio- caused by the structural reduction stemming from medicine on a pilot scale. The production of FSH the use of single-chain antibodies (scFVs). The other with national technology will bring a series of bene- advantage is that the conception of the proposed tool fits, amongst which a reduction in the end price, is perfectly suited to the expression of antibodies in which makes it possible to contemplate its early in- bacterian systems which, consequently, should redu- troduction into the internal market. ce the time and cost of production. The tool can also be useful for the optimization of antibodies, reducing the occurrence of non-specific molecular recogni- Research and Development tions by means of the refinement of molecular inte- 417 of Construction Process Using ractions. The commercial possibilities prospected on Pre-Fabricated Armed Concrete the basis of AvEvo include biomedicines, imaging Panels Reinforced with diagnostic markers and development of diagnostic Expanded Polystyrene Core: kits, among others. Application for One-Storey Houses

Coordinator: Production Luciana Alves de Oliveira 416 of Human FSH by Company: Recombinant Engineering R.C. Construções Ltda. Coordinator: Approved value: Karla de Melo Lima Phase 1: R$ 65,020

Company: The objective of this project is to research and Nanocore Biotecnologia Ltda. develop a construction process using panels of pre- Approved value: fabricated armed concrete reinforced with expanded Phase 1: R$ 69,480 polystyrene core for use in one-storey houses. The work includes the evaluation of performance with The present project aims to optimize a technique regard to compliance with the regulations laid down for the production of follicle-stimulant hormone by law in Norm CE 02.136.01, of the Brazilian Asso- (FSH) obtained by recombinant technology from ciation of Technical Norms (ABNT) for buildings of mammal cells, developing a process for the commer- up to five stories. The viability study to be underta- cialization of the first recombinant produced in Bra- ken in phase 1 of the project, involves the stages of zil. This concerns an innovative proposal which ori- data gathering/theoretical analysis of the perfor- ginated in the University of São Paulo, the industrial mance of the proposed construction process; analy- process for which will be developed in partnership sis and evaluation of the existing interfaces; study of with Nanocore. The implementation of this project the dosage of concrete to be used in the make-up of will be fundamental to confirm the industrial inven- the panels; creation of a base-architectonic design; tiveness and viability of the process, with the ultima- manufacture of the panels and assembly of the pro- te goal of securing the registration of their intellec- totype; performance trials and their respective eva- tual property. The intention is to optimize and luation; and, finally, evaluation of the technico-eco- outline the steps for the production and purification nomic viability of the proposed construction process of rhFSH in conditions of good manufactu- process. The appropriate development of a cons- ring practice for use in human medicine. Among the truction technology such as this has many technical specific objectives of the project, the following contributions to give to the sector, such as the con- should be noted: 1) the characterization of the solidation of prefabricated construction methods rhFSH producing clone; 2) the creation of a Referen- and processes; the introduction of industrialized ce Cell Bank and a Working Cell Bank as reliable and construction techniques which increase productivity continuous sources from which the rhFSH can be and the quality of the buildings; and the supplying consistently produced; and 3) the establishment of of a finished product that offers guarantees, decrea- the culture in bioreactors, evaluating the cell growth sing the high incidence of pathologies in buildings.

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Development of means of dip coating with anti-abrasive, bactericidal 418 Vitroceramic composite and aestivating properties. These coatings will be ap- for Dental Applications plied on metal surfaces, but specifically on steels.

Coordinator: Luiz Carlos de Carvalho Production of Adsorbents and Chiral Columns and their use Company: 420 in the Process to Obtain EDG Equipamentos e Controles Ltda. Nantiomerically Enriched Substances Approved value: through Liquid Chromatography Phase 1: R$ 84,000 Coordinator: The basic idea of this project is to develop a vi- Marcos José Souza Carpes troceramic composite for application in dental res- Company: toration aiming for the development of a prosthesis (Under Formation) entirely composed of ceramic materials. The manu- facture of a restorative composite of this type is a Approved value: challenge for materials science and engineering, sin- Phase 1: R$ 83,800 ce generally the work requires short processing times and low retraction during thermic treatment. In ad- The growing importance attributed to the use of dition, the ceramic restoration needs to be translu- nantiomerically pure medicines, that is, in the form of cent and offer high resistance to fracture. Therefore, a single optical isomer, has awoken the interest of the the strategy to be employed is to develop a porous pharmaceutical industry and the scientific commu- ceramic matrix or skeleton in which a glass will be nity in the development of sophisticated separation infiltrated, producing in this manner, a composite. techniques of chiral compounds, used mainly as me- The creation of the vitroceramic prosthesis aims to dicines. Liquid chromatography is a technique for ob- replace the current metal-based dental prostheses. taining pure nantiomers which stands out amongst This development should permit the EDG Equipa- other techniques, principally after the development mentos to enter the market of consumable dental and commercial availability of chiral stationary pha- materials, as well as diminish Brazilian dependence ses recognition of high quality and capacity, which on imported dental materials. operate under severe pressure conditions and with va- rious types of moving phase. Within chromatogra- phic processes, a system which awakens great interest Application of Ceramic in the separation of chirals is the continuous process Coating on Metal Surfaces known as simulated moving bed (SMB) which sur- 419 passes, in productivity and savings on solvent, tradi- Coordinator: tional batch chromatography, with no diminution in Luiz Gustavo Pagotto Simões the purity of the products generated. Aiming for the establishment of this technology in Brazil, the De- Company: partment of Biotechnical Processes in the Faculty of Science Solution Ltda. Chemical Engineering of the State University of Cam- Approved value: pinas (Unicamp) set up an SMB unit for the separa- Phase 1: R$ 77,888.48 tion of racemic mixtures. Coinciding with setting up of the unit, research was undertaken into the develop- In recent years, the development of nanostructu- ment of adsorbents of chiral recognition based on red ceramic materials and fine films has progressi- polysaccharides for the production of chromatogra- vely increased, with coating applications in the auto- phic columns used in SMB. The company being set mobile industry and even in the textile industry. up should carry out activities which involve the tech- This project will address fundamental aspects of the nologies studied and developed, such as the applica- synthesis and processing of materials, as well as tech- tion of liquid chromatography for the separation of nological aspects such as optical, chemical and bac- racemics and the production of chiral stationary pha- tericidal properties. It is intended to synthesize by ses for the production of columns, on an analytical or the polymeric precursor method Zr02, Ti02 and preparatory scale, which could eventually be com- AI203 (ceramic materials) and deposit fine films by mercialized or applied to SMB.

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Development of Unit Staged Production of Banana 421 for Plasma Treatment of 422 Seedlings in Three Models of Bioreactor. Town Refuse, with Challenges of Optimizing the Production of Synthesis Gas Marriage of Micropropagation Techniques for the Supply of Coordinator: Healthy Genetically Improved Banana Maria Antonia dos Santos Coordinator: Company: Reusi Inês Bossi Multivacuo Indústria e Comércio de Filtros Ltda. Company: ProClone Comércio de Mudas Matrizes Ltda. Approved value: Phase 2: R$ 399,533.60 Approved value: Phase 1: R$ 81,800 / US$ 2,150 Taking as its premise the growing need to deve- lop safe processes for the final destination of diffe- The initial objective of this project, in its first rent types of refuse, the present project’s main ob- phase, is based on the evaluation of the efficiency of jective is to propose an innovative concept of a three types of bioreactor with regard to the techno- factory for the treatment of those materials. This logy employed: temporary immersion, bubbling and entails a development that will permit a final desti- nebulization. The equipment will be used in the in nation for refuse of diverse origin, in a safe, effi- vitro micropropagation of bananas, in comparison cient and competitive way. To do this, thermic plas- with the traditional procedure. The evaluation of the ma will be used as a means of very high bioreactors’ efficiency will be based on the following temperature treatment, conceived for the produc- criteria: operational performance; reduction in the tion of synthesis gas (SG) and integrated with a gas use of biological material (culture medium); mini- turbine, under development in the company ma- mization of infrastructural costs (especially electric king this proposal, for the co-generation of energy. energy); multiplication rate of seedling in vitro; and Based on developing and developed technologies, average time for acclimatization, robustness and on the technical expertise and the accumulated health in the seedlings. With the most efficient bio- experience of the project partners – Institute of Ae- reactor chosen, in the second phase it is intended to ronautical Technology (ITA), Institute for Techno- establish the protocols for micropropagation which logical Research (IPT) and Multivácuo – it is pro- permit the multiplication of seedlings above the fifth posed in this phase to build an thermic plasma subculture, actually a limiting factor permitted wi- experimental factory with capacity to destroy up to thout the occurrence of somaclonal variation. Me- 100 kg/h of solid dry material. The plasma reactor ristems of several banana clones will be installed and will be redesigned on the basis of an oven already indexation will be carried out for the virus. used in earlier research on the treatment of waste from the galvanoplastics industry. Inside it will use already developed plasma torches of the transferred Use of Cell Culture in Monitoring and non-transferred arc type. Accessory systems al- 423 Toxicity and in the Investigation ready existing in IPT will be recovered and used, of Anti-Tumoral Compounds: amongst them power sources for plasma, a system Evaluation of Cell Death for demineralization and ionization of water for plasma torch and source. The materials to be used Coordinator: for the initial trials will be specially prepared so as Patrícia da Silva Melo to simulate waste products known as RDF (refuse Company: derived fuel), with special care not to introduce or- STQ Comércio e Serviços ganochlorated matter which during pyrolysis can de Tecnologia Química Ltda. produce extremely dangerous compounds, such as dioxins and furans. Approved value: Phase 1: R$ 44,000 / US$ 17,749.00

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The main objective of this project is to evaluate limited resolution of the CCD sensors. Case studies the cytotoxicity of xenobiotics, chemical and natural have shown that these problems can be circumven- compounds, medicines, products used in the cosme- ted, making it possible to use the full potential of this tics industry and the effluents in the paper and tex- type of sensor for thematic, topographical and subs- tile industries subjected or not to treatments aimed cription mapping of small areas, with great flexibi- at detoxification on several cellular models: the cul- lity compared to conventional aerial and orbital sen- ture of V79 cells, leucemic cell lines and the primary sors. In this project it is intended to evaluate some cultures of hepatocytes isolated from fish and rats. alternatives and develop a methodology which per- Analysis of the viability in V79, leucemic and hepa- mits the use of non-metric digital cameras for map- tocytes cells, will be carried out by means of usual ping. It is intended to study and implement a plat- toxicity indicators, such as: reduction of the MTT, form with two converging cameras and verify its incorporation of neutral red, tripan-blue exclusion applicability to mapping, taking into consideration and quantification of nucleic acids. In the hepatocy- the problems of instability of internal orientation tes, in addition to the tests mentioned, the activity of parameters and image quality. the metabolization system of xenobiotics (cytochro- me P450 and conjugases) will be evaluated, given that the liver is recognized to be the main place for Miniaturized biotransformation. Keeping in mind the application 425 Fluorescence Detection and the characteristics of different cellular types in Systems for DNA Analysis toxicity evaluations, this project will have, therefore, as an overall objective the monitoring of the degree Coordinator: of toxicological compromise using, for this, models Sandro Hillebrand of cell cultures and cytotoxicity tests, evaluating the Company: induction of cell death by apoptosis and measure- Cientistas Associados, Comércio, Representação, ment of enzymatic activities of the hepatic detoxifi- Consultoria e Treinamento Ltda. cation system. Approved value: Phase 1: R$ 97,362 Airborne System for Acquisition 424 and Post-Processing of Images This project aims to develop a system for detec- Taken with Digital Cameras ting miniaturized fluorescence for application as a detector in separation techniques geared to DNA Coordinator: analysis. The general objective of phase 1 is the deve- Roberto da Silva Ruy lopment of a system for the detection and conditio- ning/acquisition of the signal which will be applied, Company: in the second phase, in the building of an instrument ENGEMAP - Engenharia e Mapeamento Ltda. for genetic analyses (such as paternity exams and the Approved value: detection of transgenics, among others) or even in Phase 2: R$ 130,975 / US$ 96,220 the sequencing of DNA. The specific objective of the first phase of the project is to transfer, from the aca- With the evolution of digital sensors for the ac- demic environment to a technology-based small quisition of images, the use of digital cameras has company, knowledge about the building of a system grown in photogrammetry, especially non-metric for detection by fluorescence, taking into considera- cameras, given that metric cameras are very expensi- tion aspects relating to its application for DNA ve and present problems with image storage and ma- analysis. In addition, the technology will be develo- nagement. Furthermore, if the non-metric cameras ped in such a way as to make it possible to build a were properly calibrated, they could offer quality in- commercially viable prototype. It will be linked up formation, combined with the advantages they offer, to a modular capillary electrophoresis system for the such as flexibility regarding focusing interval. They evaluation of performance and validation in the are small, easy to use and their cost is low when com- analysis of fragments of DNA, marked with fluores- pared with metric digital cameras. However, digital cent colorings. In addition to this main application, cameras have some limitations, such as the instabi- the technology employed in the system could be used lity of the internal geometry of the camera (focal in other instruments, such as systems for flow analy- distance and position of the main subject) and the ses, Elisa plate readers, PCR in real time and in chro-

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matography and electrophoretic separation techni- Company: ques. The innovation introduced in this project is Electrocell Ind. e Com. Ltda. the use, in the same system, of LEDs as an excitation Approved value: source, avalanche photodiodes as detectors of emit- Phase 1: R$ 45,800 / US$ 9,840.07 ted fluorescence and the synchronous detection in the signal conditioning for the analysis of DNA. The technology acquired by the company with the support of FAPESP culminated in the develop- ment of the largest fuel cell in the southern hemis- Software for the Registration phere, a unit generating 50 kilowatts (Eletropaulo of Water Supply and Sewage Collection 426 project) with remote monitoring via internet. The Networks with Space Databases project presented here now aims to develop graphi- te compounds to be injected into molds with the de- Coordinator: sired technical characteristics. The result should es- Victor Emanuel Mello de Guimarães Diniz tablish the technological consolidation of a complete Company: fuel cell development package with the application Nexus Geoengenharia e Comércio Ltda. of intelligent system. The validation of this develop- ment will bring expertise to the company and the Approved value: team involved for the start of scaled production con- Phase 1: R$ 27,126 / US$ 2,560 comitant with the final tests and trials of the fuel cell. This cell should ultimately have a power of This project aims to prove the technical viability 50Kw for use in residential buildings, industries, of the development of a low cost computational sys- hospitals, schools, to offer a low level of electricity tem on a state of the art georeferenced platform, for supply to deprived communities that do not have ac- the registration and consultation of urban water sup- cess to the distribution network and, especially, to ply and sewage collection networks. The end users users who require high levels of quality, low rates of will be the autonomous water and sewage utilities power loss and great reliability. With the develop- operated by the prefectures in around 50 per cent of ment of this project, a vital stage in the generation of the country’s municipalities. Automatic registration electricity from fuel cell, the company will be ready and consultation are vital tools in the management of to begin production of these cells with entirely na- water and sewage systems, being mandatory for the tional technology and peripherals. improvement of quality, sustainability and efficiency of these systems. The projected system will have three modules. The first is the registration module, consis- 20th BIDDING INSTRUCTIONS ting of an editing and data feed graphic-based inter- face of the QT or MFC standard, capable of designing or importing elements from the most common de- Determination of Ferrite Level sign packages such as Autocad, Microstation, and 428 in Duplex and Superduplex even from a georeferenced system. The second modu- Austenoferritic Stainless Steels, in le consists of a database on the latest generation plat- Relation to the Variables: Chemical form, Oracle IX standard, PostgreSQL and even a free Composition, Solidification Mode and access relational database. The third module, for re- Thermic Treatment of Solubilization gistration enquiries, will permit access to the infor- mation from enquiry stations to a free access map ser- Coordinator: ver, through the Terralib system. The viability of the Alain Jean Isore project should be proven by the establishment of a prototype of the system in the offices of an autono- Company: mous water utility company in the State of São Paulo. Grupo Engenharia Ltda. Approved value: Phase 1: R$ 55,920 / US$ 5,338.67 Development of Injected 427 Graphite Composites Applied The aim is to design and optimize the microstruc- in Electrochemical Processes ture of duplex and superduplex stainless steels by means of control of the process variables to increase Coordinator: reliability in the use of parts cast for the manufacture Volkmar Ett

Translating Research into Business • 253 of components in pumps and valves. The manufactu- tic target. Thirty-nine of the 100 most commonly ring conditions of castings of austenoferritic stainless used drugs in clinics act directly or indirectly steels have a great influence on the microstructure, through the activation or blocking of receptors of the which could have deleterious and even catastrophic GPCRs (Menzaghi et al. 2002) type. The production effects on the mechanical, resistance to corrosion and of antibodies which recognize a specific conforma- soldability properties. In particular, of fundamental tion of GPCRs (active or inactive) represents a new importance is the control of the quantity and the and powerful technique which may be used to exa- morphology of the austenitic and ferrite phases which mine the duration and extent of physiopathological are its basis, as well as ensuring the absence of fragili- stimuli directly, which is important for basic and cli- zing phases such as the sigma phase. The composition nical research. In addition, this technique could crea- ranges specified by international norms are much te a fast and cheap screening tool for the identifica- broader than those permitted by the restrictions im- tion of drugs that are allosteric modulators of posed on levels of ferrite and no systematic data is GPCRs, enabling the development of drugs (which available correlating microstructure with chemical could be of great therapeutic and economic value) composition, conditions of solidification and solubi- with the power to activate or inhibit GPCRs in smal- lity in duplex steels defined by the most common ler doses. Proteimax, perceiving a great consumer norms. The intention is to collect this data on duplex market for antibodies with conformational specifi- and superduplex alloys defined by international norm city, intends to produce antibodies that recognize ac- ASTM 890M, of the American Society for Testing and tivated GPCRs, as well as normalizing antibodies for Materials, and also to examine the effect of variations protein quantification tests, supplying a unique, high in microstructure on the other characteristics. In the quality product for studies related to GPCRs. first phase, samples with four different compositions will be cast of two of the alloys defined by that norm with cooling conditions, reproducing what happens Optic Device in real pieces, and treatments with variation of the 430 for Broadband temperature of solubility. The fractions and morpho- Integrated Access logy of the ferrite will be determined, as will the pre- sence of sigma phase, and traction, hardness and re- Coordinator: sistance to impact tests will be carried out. In the Aldemar Fernandes Parola second phase, tests on resistance to corrosion will be Company: carried out and a deeper study will be undertaken of AsGa S/A the solidification conditions, mapping variations in the structure with regard to the position of a repre- Approved value: sentative part of most frequently used castings. Expe- Phase 2: R$ 399,980.50 riments will also be carried out with products obtai- ned by centrifuged casting and with micro-additions Among the current products developed and for structural refinement. commercialized by AsGa are the 2E1 Ad optic mo- dem and media converters. The 2E1 Ad optic mo- dem, which represents about 10 per cent of the com- Conformation-Specific Antibodies: pany’s turnover, needs to be redesigned due to the 429 Proposal for Generation of obsolescence of some of its components. Taking ad- Antibodies Directed at Receptors vantage of this idea, it is intended to develop three Linked to Active G protein (GPCRs) new products to cater for new market segments. These are 1) the MMO 2E1 Ad Plus – multiplexer Coordinator: and 2E1 optic modem with E1, V.35/V.36 tributaries Andréa Sterman Heimann and with 4Mb/s rates on the electrical ag- gregate and 8 Mb/s on the optical aggregate; 2) the Company: CM2E1 – multiplexer and 2E1 optic modem moun- Proteimax S/C Ltda. ted in a chassis of media converters; and 3) the B- Approved value: IAD – optic device for integrated broadband access Phase 1: R$ 45,000 / US$ 6,000 with E1, V.35/V.36 tributaries and Ethernet with 68 Mb/s rates on the electrical aggregate and the optical Receptors attached to the G (GPCRs) protein aggregate. Since it is suspected that this last device have shown themselves to be an interesting therapeu- will be exported to other countries, it was named the

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Broadband Integrated Access Device (B-IAD). For Approved value: this same reason, in the initial phase of develop- Phase 1: R$ 99,900 ment, an attempt will be made to bring it up to the T1 and T3 standards required by the United States After obtaining colored gold powder by high ener- market, since this will not cause any great rise in cost gy milling in a project supported by PIPE, the com- for the products designed to meet E1 and E3 stan- pany seeks to carry out in this project research into a dards. The name of the present project is derived new way of producing jewelry in Brazil. What is pro- from this more complex product. posed here is the development of the technology of conformation of colored gold powders by compacta- tion and subsequent sinterization. The technological Study of the innovation is present in the application of powder 431 Technical Viability of a metallurgy techniques in jewelry, thus allowing the Piezoelectric Flow Pump configuration of complex pieces, which could not be achieved with casting techniques. In addition, the fi- Coordinator: nishing of the jewels occurs with a fewer number of Cícero Ribeiro de Lima stages compared to conventional techniques. The first phase of this project will research the production of Company: pieces of red (solid solution), purple (intermetallic) Inoveo Pesquisa e Desenvolvimento and blue (surface treatment) gold alloys. For each co- de Produtos e Projetos de lored gold alloy, the following processing parameters Automação de Sistemas Ltda. will be analyzed: condition for the re-cooking of the Approved value: powder; temperature and time of sinterization and Phase 1: R$ 55,900 / US$ 2,500 thermic treatment of the pieces; condition of surface finish. In the second phase, the results obtained The development of pumps for precision flow should serve as a basis for the production of pieces in has been taking place in a number of areas (such as the other colors developed: green, white, black, gray, bioengineering) for use in the pumping of blood or pink, yellow and their tonalities. in the dosage of reagents and medicines. Many of the new principles applied are based on the use of pie- zoelectric actuators. These actuators offer certain Production of advantages over other traditionally used types, such 433 Peaches in Regions with as greater potential for miniaturization, less noise Low Incidence of Cold generation and reduced number of moving parts. Thus, the present project aims to carry out the study Coordinator: of the technical viability of a new configuration of Fernando Mendes Pereira piezoelectric flow pump by means of the elaboration Company: of computational modules, the optimization of pa- Valdenir Rossi rameters and the construction of an experimental bench top prototype to check its functionality. Si- Approved value: multaneously with the technical viability study, two Phase 2: R$ 48,668 / US$ 76,359.20 products with potential application in the techno- logy being studied will be researched: water refrige- Based on previously developed innovative techni- ration systems for processors in high performance ques, in 1996 a project was begun with the aim of im- microcomputers and blood pumps for applications proving the quality of peach scions. The study exami- which involve extracorporeal circulation. ned the possibility of the propagation of stock for grafting using herbaceous material and carried out Process for Manufacture studies on new grafting stock. In the present project, of Gold Artifacts the objective is to plant high productivity orchards 432 with the production of early fruit of high quality, Coordinator: bringing together all currently available knowledge Edval Gonçalves de Araújo to test new technologies in the field. Thus, experi- ments will be carried out on high density planting Company: and on grafting stock obtained from herbaceous cut- Regulus Ars Tecnologia em Jóias Ltda. tings of umezeiro (Prunus mume) clones and from

Translating Research into Business • 255 the cv. Okinawa peach tree. New dual-purpose culti- duction line. A layer of conducting composite contai- var crowns will be tested as options for industrializa- ning high conductivity lampblack will be applied tion. Research was programmed into post-harvest between the inner layer and the outer layer, which of- procedures to determine the most suitable packaging fers the high resistance to abrasion necessary for high materials and ideal pick-up points for commerciali- durability. The external layer will avoid the build up zation in markets close to and far from the produc- of electrical charge on the belt and the mechanical tion zone. Based on the results obtained it will be properties of the belt will be maintained. possible to establish the region of Jaboticabal (SP) as an important producing center for early peaches. Development of 435 a Temperature Supervision Development of Systems System for Productive 434 with Anti-static Additive and Sectors of Red Ceramic Conductive Layers for Development of Transmission Coordinator: Belt Used in the Textile Industry José Antonio Armani Paschoal Company: Coordinator: Flyever Indústria e Comércio de Zaida Jova Aguila Equipamentos Eletrônicos Ltda. Company: Approved value: Elo Indústria e Comércio de Correias Ltda. Phase 1: R$ 68,168.50 Approved value: Phase 1: R$ 69,117.84 This proposal is aimed at the research and deve- lopment of temperature supervision for kilns and In the textile branch of industry it is common to drying chambers (ovens) in red ceramic industries use movement transmission belts in the looms, reels (blocks, floor tiles, roof tiles and ceramic pipes). It is and thread spindles. The substantial friction genera- intended, in this way, to achieve an improvement in ted when working causes an accumulation, on the quality, a reduction in cost and the training of pro- surface of the belt, of particles of dust, thread fibers fessionals in this type of industry. The project will and many other non conductive light-weight mate- consist of: 1) microprocessed digital temperature in- rials. This build-up, in time, ends up increasing the dicators and controllers with serial communication thickness of the belt, leading to alterations in the and via radio frequency; 2) serial communication speed of the system. Owing to the decrease in the units via radio frequency for the collection and sen- friction coefficient of attrition between the pulleys ding of data; and 3) supervision software for the and the belt it frequently happens that that whole monitoring and control of firing and drying of the drive mechanism becomes paralyzed. There exists on material (clay), collection of data and formulation of the Brazilian market an imported belt with which, technical guidelines for quality. The implementation possibly because of the use of antistatic agents, this of this project requires field work with research in problem does not occur. ELO developed a similar na- different localities, since ceramics activity is present tional product with mechanical properties equivalent throughout the country. In this way it will be possi- to that of the imported belt at a much lower cost. An ble to become acquainted with particular methods efficient alternative to be developed in this project is of every region, which should lead to a standardized the application to the belt of layers of composites system which optimizes the production process. The containing charge conductors. The technology invol- option for sending data via radio signal makes the ves the development of formulations of composites installation, the operational control and maintenan- and in the application process to be used on the pro- ce of the system more practical.

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