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Creating a globally competitive industry

GE Healthcare-

Ian Dale, General Manager, Global Supply Chain Life Science – Core Imaging General Electric Healthcare

Global Outlook, , August 17th 2015 Norway is well positioned to compete World Economic Forum

• Education / Competence Global Competiveness Index (relevant for Industry) and generally high technology acceptance

• Geopolitical stability (e.g. low strike frequency)

• Predictable financial conditions (e.g. stable and not too strong NOK and competitive tax levels)

• Local company cultures Collegial spirit based on social equality and high employer loyalty

• Culture to hunt productivity Based on high willingness to support change, supported by high social security.

http://reports.weforum.org/global-competitiveness-report-2014-2015/the-measurement-of-sustainable-competitiveness/ Winning culture…sometimes the margins are small GE 2014 form 10k This is GE Industrial (GE – GE Capital)

Fast Facts GE Healthcare

GE 2014 form 10k Footprint Moving Powering Curing Building

Major Nordic General Electric locations in the Nordic Region

GE has been active in the Nordic region for 50 years.

. 6,000 employees

CoE . Revenue $2.3B (2013)

. Exports of $2.9B (2013) CoE CoE CoE

CoE GE Healthcare Life Science Our vision & mission is to accelerate molecular & precision medicine

We… enable precise clinical decisions We empower Precision researchers Diagnostics with by providing advanced innovative tools & analytics in-vivo & in-vitro for protein, genetic & cell- diagnostics based research & development

We… drive end-to-end RegenerativeWe create the future medicine of customer productivity & regenerative medicine & cell capacity in global therapy with customers by biopharmaceutical manufacturing providing novel technologies & methods Life Sciences Core Imaging Imaging Agent Portfolio

Contrast Media Molecular-Imaging Molecular-Imaging SPECT PET

SPECT Targeted X-Ray/CT MRI SPECT PET

* Targeted SPECT Ultrasound

Contrast Media Supply Chain Production Process Flow Distribution Primary Chemical Secondary Production API Production (Pharmaceutical) Lindesnes (1974) Cork (1993)

Raw Materials GE Wholesaler Distribution Synthesis / Dealer Shanghai (1994) (1917) Centers

Purification Drug Substance

Drug Substance Excipients Water Hospital

Mix

Filtration

Sterilization

Label & Packaging Patient Let’s get back to winning

Creating a globally competitive industry

…..Is the Global Supply Chain a Competitive Advantage?

…..or just a cost?

Understand Reality….

Need to look in the mirror to evaluate

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Understand Reality…. Look in the mirror….

Do we need to improve and what needs to change to compete globally?

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Understand Reality…. Look in the mirror How can we improve?

Are we beating the competition?

....its a global game

To Compete Globally from Lindesnes

• As well as looking at how we compare to the competition • Use a suite of tools and GE processes • Operational Excellence (lean 6 & sigma) • Frameworks and best practices EHS/maintenance/materials/quality • Focus on Reducing Waste/Energy • Cycle time reduction • Capacity/efficiency • Operating mechanisms & closed loop mgmt • Brilliant factory approach • Utilise networks eg Eyde • Create a Purpose • Ecomagination…….50% less energy by 2005-2015 • Healthymagination……at work for a healthier world

GE Healthcare Lindesnes – An Industrial Adventure

1974 - The Worlds largest producer of drug substances for Contrast Agents , 30% of X-ray world market.

- Products are injected into 2 patients every single second (~170 000 per day !) GE Healthcare Manufacturing Landscape

80 Plants  3 Categories

Plants

System Assembly Component MFG Chemical Process 45 20 15

The GE Brilliant Factory Approach

Machine Data Machine and Line Health Optimization Quality Visualization Yield

Productivity Factory Control Optimization Fulfillment Optimization Supply Chain Foundational Optimization Elements (Level 0) Central data store – Data Warehouse and/or Data Lake Operational Excellence @Lindesnes …….Delivering Results

……world leading cost of goods ……key competitive advantage by GEHC Mfg Cost vs Competition

Fill & finish

API

GE Branded Competitor Generic Competitive Ambition + Culture of Productivity + Sense of Unease +Sense of Purpose =Competitiveness Thanks for listening

…and don’t be afraid to look in the mirror 23