DOCSLIB.ORG

Johnson & Johnson

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Johnson & Johnson Johnson & Johnson - Presenters Alyssa McCulla Anthony Esposito Renee Daggett • Current Role: Asst. Brand • Current Role: Asst. Brand • Current Role: Asst. Brand Manager, Allergy Manager, Allergy Manager, Comp Skin Consumer Promotions Professional • School: Drexel, ‘14 • School: Penn State, ’15 • School: Villanova, ’15 • Major: Communications • Major: Marketing • Major: Marketing/Business Analytics • Experience: • Experience: • JOHNSON’S® Baby, • Marketing co-op, • Experience: innovation JOHNSON’S® Baby • Marketing co-op, • Walmart team – • BENADRYL® Brand, RoC and AVEENO® analyst & shopper forecasting, CP/TP GFO • Three undergrad co- ops, Marketing & PR The #1 Health Care company in the world Decentralized management of companies in three sectors: Medical Devices & Consumer Pharmaceuticals Diagnostics Family in diverse health care business: – Pharmaceuticals – Biotechnology – Contact lenses – Over-the-counter drugs – Consumer packaged goods 265 operating companies in more than 60 countries, employing about 126,500 people Johnson & Johnson Consumer Segment 2015 Sales: $13.5 billion a science-based approach to growth connecting clinically proven efficacy with consumer insights career opportunities to work with some of the world’s most visible and respected brands Lori Kumar, Ph.D. (seen here with daughter Aparna) led the development of LISTERINE® WHITENING® Quick Dissolving Strips Johnson & Johnson Pharmaceuticals Segment 2015 Sales: $31.4 billion We are directly addressing the critical needs of patients around the world Major therapeutic areas: Oncology HIV/AIDS – 33 million people Cardiovascular and Epilepsy – 50 million people Metabolism Hepatitis C – 170 million people Neuroscience, including Pain Diabetes – 230 million people Infectious Diseases Immunology disorders – 200 million people Biologics/Immunology Schizophrenia – 50 million people Johnson & Johnson Medical Devices and Diagnostics Segment THE WORLD’S LARGEST MEDICAL TECHNOLOGY BUSINESS 2015 Sales: $25.1 billion CORDIS® DEPUY® DIABETES CARE ETHICON® ETHICON ENDO-SURGERY® ORTHO CLINICAL DIAGNOSTICS® VISION CARE Our Credo challenges us to put the needs and well-being of the people we serve first our customers our employees communities and the environment our stockholders Caring for people around the world, by anticipating their needs, creating solutions and experiences, that help them and those they care for, live healthy, vibrant lives. - J&J Consumer Sector Mission SKIN CARE OTC BABY CARE ORAL CARE COMPROMISED SKIN WHAT DOES MARKETING LOOK LIKE TO YOU? BUT WHAT ELSE IS MARKETING? In Store Displays Packaging Budget Management FSIs Forecasting New Product Innovation Digital Campaigns Pricing Consumer Research Website Updates Public Relations Business Planning Coupon Offers Consumer Promotions Brand Strategy SO IS THIS AN EXAMPLE OF GOOD MARKETING? JOHNSON’S® BABY IT’S ALL ABOUT… SO WHAT IS STRATEGY? Marketing Excellence: An Integrated Framework Brand Vision Consumer Competition Company Positioning Statement Marketing Mix BRAND VISION To win baby’s first bath by being the #1 trusted brand by Moms. BRAND STRATEGY Brand Vision Consumer Competition Company Positioning Statement Marketing Mix THE CONSUMER Ages 18-35 Places a high value on research Women being core consumer and proven effectiveness at an Without alienating men affordable price “I only want the best for my child. When I choose the products I use for her, I need to be assured that they are safe, trusted and Strong heritage and multi- gentle for my baby’s benefit claims serve as a delicate skin.” strong positioning foundation Has a baby 0-3 years old THE COMPETITION Private Label and Value Premium All-Natural Brands Brand Look-Alikes Mid-Tier Natural/Gentle Brands Professional Line Brands THE COMPANY BRAND STRATEGY Brand Vision Consumer Competition Company Positioning Statement Marketing Mix BASIC STRATEGIC QUESTIONS CONSUMER COMPETITION COMPANY WHO is our target? What are the market What is our product DIFFERENTIATION? characteristics? What key INSIGHTS do we need to know? Where are the unmet What are our product NEEDS? ATTRIBUTES? & How should we POSITION What is VALUE to this them? consumer? How will it evolve? What is your value proposition? What is the positioning statement? POSITIONING STATEMENT BRAND STRATEGY Brand Vision Consumer Competition Company Positioning Statement Marketing Mix MARKETING MIX – The 4 P’s - PRODUCT 1960 1990 2013 MARKETING MIX – The 4 P’s - PRICE $12.00 $10.99 $9.99 $9.99 $10.00 $8.00 $6.99 $6.99 $6.00 Retail PriceRetail $3.99 $4.00 $2.99 $1.00 $2.99 $2.00 $1.49 $- Private Label Baby Magic Johnson's Aveeno Baby Burts Bees CeraVe Baby Mustela California Baby Media SOV 0% 0% 78% 16% 0% 0% 2% 0% 24 Note: Retail pricing, distribution, shelving and merchandising decisions are at the sole discretion of retailer. AO 4% SOV MARKETING MIX – The 4 P’s- PLACEMENT MARKETING MIX – The 4 P’s - PROMOTION BRAND EVALUATION – SWOT ANALYSIS Strengths Weaknesses (Product) INTERNAL Opportunities Threats (Market) EXTERNAL SWOT Exercise SWOT ANALYSIS: JOHNSONS® STRENGTHS WEAKNESSES - Brand Equity - Formulas - Building Basket -BME Spend -Education (Product) -Differentiation INTERNAL OPPORTUNITIES THREATS - Natural - Co-marketing brands/competitive - Multiple - Efficacy – does it placement (Market) work? EXTERNAL - Brand relevancy WHAT IS THE BRAND VISION OF RED BULL®? EXAMPLE 1 EXAMPLE 3 EXAMPLE 2 THANK YOU! IS THERE ANYTHING YOU WANT TO ASK US? CONTACT INFORMATION • Alyssa McCulla: Assistant Brand Manager • [email protected] • Anthony Esposito: Assistant Brand Manager • [email protected] • Renee Daggett: Assistant Brand Manager • [email protected] .
Load more

Recommended publications
  • Learner Notification International Society for Heart & Lung
    Learner Notification International Society for Heart & Lung Transplantation (ISHLT) 41st Annual Meeting & Scientific Sessions Virtual Experience April 24 – 28, 2021 Live Virtual Acknowledgement of Financial Commercial Support Abbott Medtronic United Therapeutics Acknowledgement of In-Kind Commercial Support No in-kind commercial support was received for this educational activity. Satisfactory Completion Learners must complete an evaluation form to receive a certificate of completion. Your chosen sessions must be attended in their entirety as partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed below, it is your responsibility to contact your licensing/certification board to determine course eligibility for your licensing/certification requirement. Physicians (ACCME) The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation Statement - ISHLT designates this live virtual activity for a maximum of 32.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Accreditation Statement In support of improving patient care, this activity has been planned and implemented by Amedco LLC and ISHLT. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Nurses (ANCC) - Credit Designation Statement - Amedco LLC designates this live virtual activity for a maximum of 32.00 ANCC contact hours. Pharmacists (ACPE) - Credit Designation Statement - Amedco LLC designates this live virtual activity for a maximum of 32.00 knowledge-based CPE contact hours.
    [Show full text]
  • 2015 Annual Report
    ANNUAL REPORT 2015 MARCH 2016 TO OUR SHAREHOLDERS ALEX GORSKY Chairman, Board of Directors and Chief Executive Officer This year at Johnson & Johnson, we are proud this aligned with our values. Our Board of WRITTEN OVER to celebrate 130 years of helping people Directors engages in a formal review of 70 YEARS AGO, everywhere live longer, healthier and happier our strategic plans, and provides regular OUR CREDO lives. As I reflect on our heritage and consider guidance to ensure our strategy will continue UNITES & our future, I am optimistic and confident in the creating better outcomes for the patients INSPIRES THE long-term potential for our business. and customers we serve, while also creating EMPLOYEES long-term value for our shareholders. OF JOHNSON We manage our business using a strategic & JOHNSON. framework that begins with Our Credo. Written OUR STRATEGIES ARE BASED ON over 70 years ago, it unites and inspires the OUR BROAD AND DEEP KNOWLEDGE employees of Johnson & Johnson. It reminds OF THE HEALTH CARE LANDSCAPE us that our first responsibility is to the patients, IN WHICH WE OPERATE. customers and health care professionals who For 130 years, our company has been use our products, and it compels us to deliver driving breakthrough innovation in health on our responsibilities to our employees, care – from revolutionizing wound care in communities and shareholders. the 1880s to developing cures, vaccines and treatments for some of today’s most Our strategic framework positions us well pressing diseases in the world. We are acutely to continue our leadership in the markets in aware of the need to evaluate our business which we compete through a set of strategic against the changing health care environment principles: we are broadly based in human and to challenge ourselves based on the health care, our focus is on managing for the results we deliver.
    [Show full text]
  • Drug Information Center Highlights of FDA Activities
    Drug Information Center Highlights of FDA Activities – 9/1/20 – 9/30/20 FDA Drug Safety Communications & Drug Information Updates: Efficacy & Safety Concerns for Atezolizumab in Combination with Paclitaxel 9/8/20 The FDA alerted health care professionals and patients that a clinical trial evaluating atezolizumab plus paclitaxel in patients with previously untreated inoperable locally advanced or metastatic triple negative breast cancer that the drug combination was not effective. The combination of atezolizumab with another paclitaxel formulation, paclitaxel protein‐bound, is currently approved for use in adult patients with metastatic triple negative breast cancer, but this continued approval may be contingent on the results of additional studies. Paclitaxel should NOT be used as a replacement for paclitaxel protein bound in clinical practice. Electronic Expanded Access Requests 9/23/20 The FDA announced that the Reagan‐Udall Foundation has launched Expanded Access eRequest, a tool to submit expanded access requests for individual patient expanded access for drugs and biologics in non‐emergency settings. The tool allows auto population of forms, uploading of relevant documents, links to resources for physicians, patients, and caregivers, and secure application submission to the FDA. Benzodiazepine Drug Class: Drug Safety Communication ‐ Boxed Warning Update 9/23/20 The FDA is requiring the Boxed Warning be updated for all benzodiazepines to address serious risks of abuse, addiction, physical dependence, and withdrawal across the medication class. Changes are also being incorporated in the Medication Guides, and other sections of the prescribing information including the Warnings and Precautions, Drug Abuse and Dependence, and Patient Counseling Information sections. Diphenhydramine (Benadryl): Serious Problems with High Doses 9/24/20 The FDA issued a warning that taking higher than recommended doses of the common OTC allergy medication diphenhydramine (Benadryl) can lead to serious heart problems, seizures, coma, or even death.
    [Show full text]
  • Mcneil Consumer : Mdl No
    IN THE UNITED STATES DISTRICT COURT FOR THE EASTERN DISTRICT OF PENNSYLVANIA IN RE: MCNEIL CONSUMER : MDL NO. 2190 HEALTHCARE, ET AL., MARKETING : AND SALES PRACTICES LITIGATION : : Applies to: : ALL ACTIONS : MEMORANDUM McLaughlin, J. July 13, 2012 This multidistrict litigation arises out of quality control problems at the defendants’ facility manufacturing over- the-counter healthcare products in Fort Washington, Pennsylvania, which led to a series of recalls of those products. The named plaintiffs assert claims for economic loss on behalf of a putative nationwide class against Johnson & Johnson (“J&J”), McNeil Consumer Healthcare (“McNeil”), and four of their executives. The plaintiffs allege that they overpaid for the defendants’ products as a result of the recalls and the defendants’ scheme to conceal or downplay the scope of the quality control problems. The defendants, who have offered a coupon or cash refund to consumers who purchased recalled drugs, have moved to dismiss the operative complaint, and assert that the named plaintiffs lack constitutional standing and have not met the applicable pleading standard. The Court will grant the defendants’ motion because the plaintiffs have not pled facts that show a cognizable injury in fact, which is required to confer Article III standing. I. Procedural Background This litigation resulted from the consolidation of ten individual actions filed around the country. Haviland v. McNeil Consumer Healthcare, No. 10-2195, was filed in this Court on May 12, 2010, asserting economic injuries arising out of the April 30, 2010 recall of over-the-counter children’s drugs by McNeil, a part of the J&J “Family of Companies.” Eight additional cases, also arising out of the April 2010 recall, were filed in district courts around the country.1 All cases asserted claims for economic injury only, with the exception of Rivera v.
    [Show full text]
  • Approved Prenatal Medications Pain Medications • Tylenol
    Approved Prenatal Medications Pain Medications Tylenol (acetaminophen) for minor aches and pains, headaches. (Do not use: Aspirin, Motrin, Advil, Aleve, Ibuprofen.) Coughs/Colds Robitussin (Cough) Robitussin DM (non-productive cough) DO NOT USE TILL OVER 12 WEEKS Secrets and Vicks Throat Lozenges Mucinex Sore Throat Chloraseptic spray Saline Gargle Sucrets and Vicks Throat Lozenges Antihistamines/Allergies Zyrtec Claritin Benadryl Dimetapp Insomnia Benadryl Unison Hemorrhoids Preparation H Tucks Anusol Diarrhea Imodium (1-2 doses- if it persists please notify the office) BRAT diet (bananas, rice, applesauce, toast) Lice RID (only!) DO NOT USE Kwell Itching Benadryl Calamine or Caladryl Lotion Hydrocortisone cream Heartburn, Indigestion, Gas Tums Gas-X Mylanta Pepcid Maalox Zantac *DO NOT USE PEPTO BISMOL- it contains aspirin Decongestants Sudafed Robitussin CF- Only if over 12 weeks Tavist D Ocean Mist Nasal Spray (saline solutions) Nausea Small Frequent Meals Ginger Ale Vitamin B6 Sea Bands Yeast Infections Monistat Mycolog Gyne-lotrimin Toothache Orajel May see dentists, have cavity filled using Novocain or lidocaine, have x-rays with double lead shield, may have antibiotics in the Penicillin family (penicillin, amoxicillin) Sweetners- all should be consumed in moderation with water being consumed more frequently Nutrisweet (aspartame) Equal (aspartame) Splenda (sucralose) Sweet’n Low (saccharin) *note avoid aspartame if you have phenylketonuria (PKU) Constipation Colace Fibercon Citrucel Senokot Metamucil Milk of Magnesia Fiberall Miralax Eczema Hydrocortisone Cream Medications to AVOID Accurate Lithium Paxil Ciprofloxacin Tetracycline Coumadin Other Chemicals to AVOID Cigarettes Alcohol Recreational Drugs: marijuana, cocaine, ecstasy, heroin .
    [Show full text]
  • Over-The-Counter (OTC) Medications Applies To: Tufts Health Ritogether and Tufts Health Together*
    Over-the-Counter (OTC) Medications Applies to: Tufts Health RITogether and Tufts Health Together* As communicated in the November 1, 2018 Provider Update, the following changes are effective for fill dates on or after January 1, 2019. As a result of this change, some OTC medications will require prior authorization in certain circumstances as outlined below: Brand-Name OTC Medication Has a Covered Interchangeable Generic Version Available Afrin No Drip Advil capsule Advil tablet Advil PM tablet Afrin Nasal Spray Original nasal solution Afrin No Drip Aveeno Oatmeal Severe nasal Aleve tablet Baciguent ointment Benadryl capsule Bath Pak Treatment solution Benadryl Allergy Benadryl Allergy Benadryl Allergy Benadryl Extra Benefiber powder tablet capsule Liquid Strength cream Caltrate 600 +D Centrum Silver Betadine Swabstick Caltrate + D tablet Centrum liquid Plus Minerals tablet tablet Centrum Silver Centrum Ultra Men’s Children’s Advil Centrum tablet Cheracol-D syrup Adult 50+ tablet tablet suspension Children’s Benadryl Citracal Calcium + Children’s Benadryl Children’s Tylenol Chlor-Trimeton Allergy chewable D Slow Release Allergy liquid suspension syrup tablet tablet Citrucel Fiber Claritin-D 12 hour Claritin-D 24 hour Clear Cough Liquid Citrucel tablet Laxative powder tablet tablet PM Dimetapp DM Dex4 Fast Acting Dimetapp Cold and Colace capsule Conceptrol 4% gel Cough and Cold Glucose liquid Allergy elixir elixir Dristan nasal spray Dulcolax tablet D-Vi-Sol liquid Ecotrin tablet Evac powder Ex-Lax chewable Gas-X chewable Feosol tablet
    [Show full text]
  • July 21, 2021
    1 2nd Quarter 2021 Earnings Call July 21, 2021 Cautionary Note on Forward-looking Statements This presentation contains “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things: future operating and financial performance, product development, market position and business strategy. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Johnson & Johnson. Risks and uncertainties include, but are not limited to: risks related to the impact of the COVID-19 global pandemic, such as the scope and duration of the outbreak, government actions and restrictive measures implemented in response, material delays and cancellations of medical procedures, supply chain disruptions and other impacts to the business, or on the Company’s ability to execute business continuity plans, as a result of the COVID-19 pandemic; economic factors, such as interest rate and currency exchange rate fluctuations; competition, including technological advances, new products and patents attained by competitors; challenges inherent in new product research and development, including uncertainty of clinical success and obtaining regulatory approvals; uncertainty of commercial success for new and existing products; challenges to patents; the impact
    [Show full text]
  • Benadryl (Diphenhydramine) Dosing Chart
    1084 Cromwell Avenue Rocky Hill, CT 06067 (860) 721-7561 – Phone (860) 721-9199 – Fax Benadryl (Diphenhydramine) Dosing Chart *Ages 6 months & above* Dose every 6 hours: Dose for hives and/or itching. In general, once hives have started, you should continue regular dosing until there have not been hives for the entire day. Benadryl (Diphenhydramine) Liquid: Chewable Tablets: Tablets: Weight: 12.5mg/5ml 12.5mg each 25 mg each 17-21 pounds ¾ tsp. (3.75ml) Use Liquid Use Liquid Use 22-32 pounds 1 tsp. (5ml) 1 tablet Liquid or Chews Use 33-42 pounds 1 ½ tsp. (7.5ml) 1 ½ tablets Liquid or Chews 43-53 pounds 2 tsp. (10ml) 2 tablets 1 tablet 54-64 pounds 2 ½ tsp. (12.5ml) 2 ½ tablets 1 tablet 65-75 pounds 3 tsp. (15ml) 3 tablets 1 tablet 76-86 pounds 3 ½ tsp. (17.5ml) 3 ½ tablets 1 tablet >86 pounds 4 tsp. (20ml) 4 tablets 2 tablets EDUCATION ON CALL Administering Medicine Safely When your child isn’t feeling well, you want to relieve their discomfort as quickly as possible. Be prepared with information that can help you understand the differences between pediatric pain relievers and fever reducers, and how to administer them safely. Always read the label 1. Active ingredient: Ingredient that makes the medicine work 2. Uses: Symptoms the medicine treats 3. Directions: The amount of medicine to give and how often Know the difference TYLENOL® MOTRIN® Active ingredient: Acetaminophen Active ingredient: Ibuprofen • Treats pain & fever • Treats pain & fever • Gentle on tummies • Lasts up to 8 hours • Dosing available from your pediatrician for • Can be used for children 6 months of age or older children 6 months and younger Never give aspirin to children.
    [Show full text]
  • Medication Code Key: PMCODE and Drug Name in 2007 NHHCS Cdc-Pdf
    Medication Code Key: PMCODE and Drug Name in 2007 NHHCS PMCODE Drug Name 00002 TAMIFLU 00003 DITROPAN XL II 00004 LIDODERM PATCH 00008 VIACTIV 00010 A AND D II 00013 MYCOPHENOLATE MOFETIL 00017 SIROLIMUS 00019 HAWTHORN 00027 SYNAGIS 00032 EXCEDRIN MIGRAINE 00036 MAALOX PLUS 00037 ACEON 00038 GLYSET 00039 SONATA 00042 PROTONIX 00044 PANLOR DC 00048 MOBIC 00052 SILDENAFIL CITRATE 00053 TAMSULOSIN HYDROCHLORIDE 00054 COMTAN 00058 MINERAL SUPPLEMENT 00061 BISMUTH 00071 CERTAVITE 00073 LUXIQ 00075 SAL-TROPINE 00076 TRILEPTAL 00078 AGGRENOX 00080 CARBIDOPA-LEVODOPA 00081 EXELON 00084 PREGABALIN 00085 ORAMORPH 00096 OSTEO-BIFLEX 00099 ALOCRIL 00100 A.S.A. 00101 ISOSORBIDE DINITRATE 00102 ISOSORBIDE MONONITRATE 00107 ROSIGLITAZONE MALEATE 00109 URSODIOL 00112 MEDERMA 00113 ANDROGEL 00114 DILTIA XT 00117 CRANBERRY 00123 NICOTINE 00125 AVELOX 00132 CAL-MAG 00133 CANDESARTAN Page 1 Medication Code Key: PMCODE and Drug Name in 2007 NHHCS PMCODE Drug Name 00148 PROLIXIN D 00149 D51/2 NS 00150 NICODERM CQ PATCH 00151 TUSSIN 00152 CEREZYME 00154 CHILDREN'S IBUPROFEN 00156 PROPOXACET-N 00159 KALETRA 00161 BISOPROLOL 00167 NOVOLIN N 00169 KETOROLAC TROMETHAMINE 00172 OPHTHALMIC OINTMENT 00173 ELA-MAX 00176 PREDNISOLONE ACETATE 00179 COLLOID SILVER 00184 KEPPRA 00187 OPHTHALMIC DROPS 00190 ABDEC 00191 HAPONAL 00192 SPECTRAVITE 00198 ENOXAPARIN SODIUM 00206 ACTONEL 00208 CELECOXIB 00209 GLUCOVANCE 00211 LEVALL 5.0 00213 PANTOPRAZOLE SODIUM 00217 TEMODAR 00218 CARBAMIDE PEROXIDE 00221 CHINESE HERBAL MEDS 00224 MILK AND MOLASSES ENEMA 00238 ZOLMITRIPTAN 00239
    [Show full text]
  • Over-The-Counter (OTC) Medications
    Over-the-Counter (OTC) Medications Helpful Tips • Choose products that target your specific symptoms, rather than combination products that treat many symptoms that you may not have. See below. • Be cautious of doubling up on the same ingredients (for example, Tylenol is in many products). • Take extra care when using “PM” products, as they may have serious side effects. • Always read the product labels for important dosing and precaution information. - Doses may differ for adults and children - Many products have age limitations - Most products have a maximum number of days that they should be used OverO-thever--counterthe-counter options options Over-the-Counter Options CombinationCombination Products: Products: treat multipletreat multiple symptoms symptoms Combination products often results in overtreating because you’re taking medications for Combination Products: Treat multiple symptoms Combination• products often results in overtreating because you’re taking medications for • symptoms that you do not have. • Combination products often result in overtreating because you’re taking medications for symptoms that you do not have. Instead,Over choose-the- counteran over-the options-counter p roduct that targets your specific symptoms with symptoms that you do not have. •Instead, choose an over-the-counter product that targets your specific symptoms with • ingredients only for those symptom • Instead, choose an over-the-counter product that targets your specific symptoms with Combination Products:ingredients treat multipleonly for thosesymptoms
    [Show full text]
  • Transdermal Nicotine Maintenance Attenuates the Subjective And
    Neuropsychopharmacology (2004) 29, 991–1003 & 2004 Nature Publishing Group All rights reserved 0893-133X/04 $25.00 www.neuropsychopharmacology.org Transdermal Nicotine Maintenance Attenuates the Subjective and Reinforcing Effects of Intravenous Nicotine, but not Cocaine or Caffeine, in Cigarette-Smoking Stimulant Abusers 1 1 ,1,2 Bai-Fang X Sobel , Stacey C Sigmon and Roland R Griffiths* 1Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA The effects of transdermal nicotine maintenance on the subjective, reinforcing, and cardiovascular effects of intravenously administered cocaine, caffeine, and nicotine were examined using double-blind procedures in nine volunteers with histories of using tobacco, caffeine, and cocaine. Each participant was exposed to two chronic drug maintenance phases (21 mg/day nicotine transdermal patch and placebo transdermal patch). Within each drug phase, the participant received intravenous injections of placebo, cocaine (15 and 30 mg/70 kg), caffeine (200 and 400 mg/70 kg), and nicotine (1.0 and 2.0 mg/70 kg) in mixed order across days. Subjective and cardiovascular data were collected before and repeatedly after drug or placebo injection. Reinforcing effects were also assessed after each injection with a Drug vs Money Multiple-Choice Form. Intravenous cocaine produced robust dose-related increases in subjective and reinforcing effects; these effects were not altered by nicotine maintenance. Intravenous caffeine produced elevations on several subjective ratings; nicotine maintenance did not affect these ratings. Under the placebo maintenance condition, intravenous nicotine produced robust dose-related subjective effects, with maximal increases similar to the high dose of cocaine; nicotine maintenance significantly decreased the subjective and reinforcing effects of intravenous nicotine.
    [Show full text]
  • Cosmetic Formulation of Skin Care Products.Pdf
    DK9685_half-series-title 4/25/06 4:34 PM Page A Cosmetic Formulation of Skin Care Products DK9685_half-series-title 4/25/06 4:34 PM Page B COSMETIC SCIENCE AND TECHNOLOGY Series Editor ERIC JUNGERMANN Jungermann Associates, Inc. Phoenix, Arizona 1. Cosmetic and Drug Preservation: Principles and Practice, edited by Jon J. Kabara 2. The Cosmetic Industry: Scientific and Regulatory Foundations, edited by Norman F. Estrin 3. Cosmetic Product Testing: A Modern Psychophysical Approach, Howard R. Moskowitz 4. Cosmetic Analysis: Selective Methods and Techniques, edited by P. Boré 5. Cosmetic Safety: A Primer for Cosmetic Scientists, edited by James H. Whittam 6. Oral Hygiene Products and Practice, Morton Pader 7. Antiperspirants and Deodorants, edited by Karl Laden and Carl B. Felger 8. Clinical Safety and Efficacy Testing of Cosmetics, edited by William C. Waggoner 9. Methods for Cutaneous Investigation, edited by Robert L. Rietschel and Thomas S. Spencer 10. Sunscreens: Development, Evaluation, and Regulatory Aspects, edited by Nicholas J. Lowe and Nadim A. Shaath 11. Glycerine: A Key Cosmetic Ingredient, edited by Eric Jungermann and Norman O. V. Sonntag 12. Handbook of Cosmetic Microbiology, Donald S. Orth 13. Rheological Properties of Cosmetics and Toiletries, edited by Dennis Laba 14. Consumer Testing and Evaluation of Personal Care Products, Howard R. Moskowitz 15. Sunscreens: Development, Evaluation, and Regulatory Aspects. Second Edition, Revised and Expanded, edited by Nicholas J. Lowe, Nadim A. Shaath, and Madhu A. Pathak DK9685_half-series-title 4/25/06 4:34 PM Page C 16. Preservative-Free and Self-Preserving Cosmetics and Drugs: Principles and Practice, edited by Jon J.
    [Show full text]