Spaceflight Affects Neuronal Morphology and Alters Transcellular Degradation of Neuronal Debris in Adult Caenorhabditis Elegans
SPACEFLIGHT AFFECTS NEURONAL MORPHOLOGY AND ALTERS TRANSCELLULAR DEGRADATION OF NEURONAL DEBRIS IN ADULT CAENORHABDITIS ELEGANS The Texas Tech community has made this publication openly available. Please share how this access benefits you. Your story matters to us. Citation Ricardo Laranjeiro, Girish Harinath, Amelia K. Pollard, Christopher J. Gaffney, Colleen S. Deane, Siva A. Vanapalli, Timothy Etheridge, Nathaniel J. Szewczyk, Monica Driscoll, Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans, iScience, Volume 24, Issue 2, 2021, https://doi.org/10.1016/j.isci.2021.102105. Citable Link https://hdl.handle.net/2346/87737 Terms of Use CC BY 4.0 Title page template design credit to Harvard DASH. iScience ll OPEN ACCESS Article Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans Ricardo Laranjeiro, Girish Harinath, Amelia K. Pollard, ..., Timothy Etheridge, Nathaniel J. Szewczyk, Monica Driscoll ricardo_laranjeiro@hotmail. com HIGHLIGHTS Spaceflight induces morphological remodeling of adult neurons in C. elegans Hyperbranching is a common response of adult neurons to spaceflight Neuronal debris accumulates in the hypodermis of proteo- stressed space-flown animals Laranjeiro et al., iScience 24, 102105 February 19, 2021 ª 2021 The Author(s). https://doi.org/10.1016/ j.isci.2021.102105 iScience ll OPEN ACCESS Article Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans Ricardo Laranjeiro,1,7,* Girish Harinath,1 Amelia K. Pollard,2 Christopher J. Gaffney,3,4 Colleen S. Deane,3 Siva A. Vanapalli,5 Timothy Etheridge,3 Nathaniel J. Szewczyk,2,6 and Monica Driscoll1 SUMMARY Extended space travel is a goal of government space agencies and private com- panies.
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