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New Appointments (India) S
GK POWER CAPSULE FOR IBPS CLERK MAINS 2015-16 government has approved the company’s raising Rs. 1,000 crore through tax free bonds, including Rs. 700 crore through public issue. 25) Current a/c deficit narrows to 1.2% of GDP in April-June. 26) The Employees Provident Fund Organisation (EPFO) increased the life insurance cover of its subscribers from 3.6 lakh to 6 lakh rupees. 27) The banks in Dakshina Kannada district conducted a mega credit camp to disburse loans under the MUDRA scheme of the Centre on September 28. 28) The World Bank has promised $30 billion financial assistance to the Railways. NEW APPOINTMENTS (INDIA) S. no Newly Appointed Post & Company 1. Subir Vithal Gokarn Executive Director on the board of the International Monetary Fund (IMF) 2. Justice Ajit Prakash Shah Ethics officer (ombudsman) at Board of Control for Cricket in India (BCCI). 3. Navtej Singh Sarna Indian High Commissioner to United Kingdom (UK) 4. V-Sivaramakrishnan (Siva) Managing Director, Oxford University Press India (OUPI) 5. Justice T S Thakur 43rd Chief Justice of India 6. Anil Kumar Jha Chairman-cum-Managing Director of Mahanadi Coalfields Ltd (MCL) 7. Deepak Singhal Executive Director of Reserve Bank of India. 8. Virender Mohan Khanna Maintenance Head of IAF 9. Harshavardhan Neotia President of FICCI. Note: He will succeed Jyotsna Suri 10. Nitish Kumar Chief Minister of Bihar (Fifth Time) 11. V Raja Vice-Chairman and Managing Director, Philips India 12. Vijay Keshav Gokhale India’s Ambassador to China. Note: He will replace Ashok Kantha 13. Zarin Daruwala India’s Chief Executive Officer at Standard Chartered Bank 14. -
NIHAA Summer 1993
The Newsletter of the NIH Alumni Association Summer 1993 Vol. 5, No . 2 date Nobel Laureate Harold Varmus Nominated as 14th NIH Director Ruth Kirschstein Named Acting Director President Clinton on A ug. 3 announced his intention to nominate Dr. Harold Eliot Varmus as the 14th director of th e National Institutes of Health. A Senate confirmation process must precede Yarmus· taking over leadership of the institutes. Winner of the Nobel Prize in 1989 for his work in cancer research. Va1111us. 53. is a professor of microbi ology. biochemistry. and biophysics. and the American Cancer Society pro fessor vfmoh:cu/ur >1iro/O£)' iJI l/Je Uni versity of California, San Francisco. He is a leader in the stu dy of cancer causing genes called "oncogenes," and an intemationall-y fecogni:z.ed authof\t-y Dr. Ruth l. Kirschsteln , acting NIH director on retroviruses. the viruses that cause Dr. Harold E. Varmus , direclor-designale AIDS and many cancers in animnl.. FIC 25 Years Old In '93 Thirty-eight-year NIH veteran Dr. Research Festival '93 Schedule Ruth Kirschstein. director of NIGM S Scholars-in-Residence (See Director p. 6) NIHAA Members Invited Program Celebrates To Alumni Symposium In This Issue Tile fas\ morning ofNCH Rc:-.c;\rch Nursing cell/er /J1·1·111111•s Festival '93-Monday. Sept. 20-has This year. the Fogarty Intern ational 17th i11s1it11tc• 111 NII/ p. ? been designated National lnsritute of Center (FIC) is 25 years old . T he cen Greeri11gs from 1/,11 1w11• NII /AA prl'sidt'lll. Diabetes and Digestive and Kidney Tltolll(IS .I. -
Advertising (PDF)
Neuroscience 2013 SEE YOU IN San Diego November 9 – 13, 2013 Join the Society for Neuroscience Are you an SfN member? Join now and save on annual meeting registration. You’ll also enjoy these member-only benefits: • Abstract submission — only SfN members can submit abstracts for the annual meeting • Lower registration rates and more housing choices for the annual meeting • The Journal of Neuroscience — access The Journal online and receive a discounted subscription on the print version • Free essential color charges for The Journal of Neuroscience manuscripts, when first and last authors are members • Free online access to the European Journal of Neuroscience • Premium services on NeuroJobs, SfN’s online career resource • Member newsletters, including Neuroscience Quarterly and Nexus If you are not a member or let your membership lapse, there’s never been a better time to join or renew. Visit www.sfn.org/joinnow and start receiving your member benefits today. www.sfn.org/joinnow membership_full_page_ad.indd 1 1/25/10 2:27:58 PM The #1 Cited Journal in Neuroscience* Read The Journal of Neuroscience every week to keep up on what’s happening in the field. s4HENUMBERONECITEDJOURNAL INNEUROSCIENCE s4HEMOSTNEUROSCIENCEARTICLES PUBLISHEDEACHYEARNEARLY in 2011 s )MPACTFACTOR s 0UBLISHEDTIMESAYEAR ,EARNMOREABOUTMEMBERAND INSTITUTIONALSUBSCRIPTIONSAT *.EUROSCIORGSUBSCRIPTIONS *ISI Journal Citation Reports, 2011 The Journal of Neuroscience 4HE/FlCIAL*OURNALOFTHE3OCIETYFOR.EUROSCIENCE THE HISTORY OF NEUROSCIENCE IN AUTOBIOGRAPHY THE LIVES AND DISCOVERIES OF EMINENT SENIOR NEUROSCIENTISTS CAPTURED IN AUTOBIOGRAPHICAL BOOKS AND VIDEOS The History of Neuroscience in Autobiography Series Edited by Larry R. Squire Outstanding neuroscientists tell the stories of their scientific work in this fascinating series of autobiographical essays. -
Cold Spring Harbor Symposia on Quantitative Biology
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME XL COLD SPRING HARBOR SYMPOSIA 0 N Q UA NTITA T1VE BIOLO G Y Founded in 1933 by REGINALD G. HARRIS Director of the Biological Laboratory 1924 to 1936 Volume I (1933).Surface Phenomena Volume II (1934) Aspects of Growth Volume III (1935) Photochemical Reactions Volume IV (1936) Excitation Phenomena Volume V (1937) Internal Secretions Volume VI (1938) Protein Chemistry Volume VII (1939) Biological Oxidations Volume VIII (1940) Permeability and the Nature of Cell Membranes Volume IX (1941) Genes and Chromosomes: Structure and Organization Volume X (1942) The Relation of Hormones to Development Volume XI (1946) Heredity and Variation in Microorganisms Volume XII (1947) Nucleic Acids and Nucleoproteins Volume XIII (1948) Biological Applications of Tracer Elements Volume XIV (1949) Amino Acids and Proteins Volume XV (1950) Origin and Evolution of Man Volume XVI (1951) Genes and Mutations Volume XVII (1952) The Neuron Volume XVIII (1953) Viruses Volume XIX (1954) The Mammalian Fetus: Physiological Aspects of Development Volume XX (1955) Population Genetics: The Nature and Causes of Genetic Variability in Population Volume XXI (1956) Genetic Mechanisms: Structure and Function Volume XXII (1957) Population Studies: Animal Ecology and Demography Volume XXIII (1958) Exchange of Genetic Material: Mechanism and Consequences Volume XXIV (1959) Genetics and Twentieth Century Darwinism Volume XXV (1960) Biological Clocks Volume XXVI (1961) Cellular Regulatory Mechanisms Volume XXVII (1962) Basic -
समाचार पत्र से चियत अंश Newspapers Clippings
Jan 2021 समाचार पत्र से चियत अंश Newspapers Clippings A Daily service to keep DRDO Fraternity abreast with DRDO Technologies, Defence Technologies, Defence Policies, International Relations and Science & Technology खंड : 46 अंक : 17 23-25 जनवरी 2021 Vol. : 46 Issue : 17 23-25 January 2021 रक्षा िवज्ञान पुतकालय Defence Science Library रक्षा वैरक्षाज्ञािनकिवज्ञानसूचना एवपुतकालयं प्रलेखन क द्र Defence ScientificDefence Information Science & Documentation Library Centre - मेरक्षाटकॉफवैज्ञािनकहाउस,स िदलीूचना एवं 110प्रलेखन 054क द्र Defence ScientificMetcalfe Information House, Delhi & ‐ Documentation110 054 Centre मेटकॉफ हाउस, िदली - 110 054 Metcalfe House, Delhi‐ 110 054 CONTENTS S. No. TITLE Page No. DRDO News 1-17 DRDO Technology News 1-17 1. डीआरडीओ ने �कया �माट� एंट� एयरफ��ड वेपन का सफल उड़ान पर��ण 1 2. Successful flight test of Smart Anti Airfield Weapon 2 3. Visit of Vice Chief of the Air Staff to CAW, DRDO Hyderabad and Air Force 2 Academy 4. वाय ु सेना उप�मुख ने सीएड��य,ू डीआरडीओ हैदराबाद और वाय ु सेना अकादमी का दौरा �कया 3 5. India working on 5th-generation fighter planes: IAF Chief 4 6. DRDO successfully tests smart anti-airfield weapon for 9th time 5 7. भारत ने बनाया एक और खतरनाक और �माट� ह�थयार, द�मनु के हवाई रनवे को पलभर म� कर 6 देगा तबाह 8. Air Marshal HS Arora Param visits DRDO Hyderabad, flies Pilatus PC-7 Trainer 7 Aircraft sortie 9. -
Introduction and Historical Perspective
Chapter 1 Introduction and Historical Perspective “ Nothing in biology makes sense except in the light of evolution. ” modified by the developmental history of the organism, Theodosius Dobzhansky its physiology – from cellular to systems levels – and by the social and physical environment. Finally, behaviors are shaped through evolutionary forces of natural selection OVERVIEW that optimize survival and reproduction ( Figure 1.1 ). Truly, the study of behavior provides us with a window through Behavioral genetics aims to understand the genetic which we can view much of biology. mechanisms that enable the nervous system to direct Understanding behaviors requires a multidisciplinary appropriate interactions between organisms and their perspective, with regulation of gene expression at its core. social and physical environments. Early scientific The emerging field of behavioral genetics is still taking explorations of animal behavior defined the fields shape and its boundaries are still being defined. Behavioral of experimental psychology and classical ethology. genetics has evolved through the merger of experimental Behavioral genetics has emerged as an interdisciplin- psychology and classical ethology with evolutionary biol- ary science at the interface of experimental psychology, ogy and genetics, and also incorporates aspects of neuro- classical ethology, genetics, and neuroscience. This science ( Figure 1.2 ). To gain a perspective on the current chapter provides a brief overview of the emergence of definition of this field, it is helpful -
2004 Albert Lasker Nomination Form
albert and mary lasker foundation 110 East 42nd Street Suite 1300 New York, ny 10017 November 3, 2003 tel 212 286-0222 fax 212 286-0924 Greetings: www.laskerfoundation.org james w. fordyce On behalf of the Albert and Mary Lasker Foundation, I invite you to submit a nomination Chairman neen hunt, ed.d. for the 2004 Albert Lasker Medical Research Awards. President mrs. anne b. fordyce The Awards will be offered in three categories: Basic Medical Research, Clinical Medical Vice President Research, and Special Achievement in Medical Science. This is the 59th year of these christopher w. brody Treasurer awards. Since the program was first established in 1944, 68 Lasker Laureates have later w. michael brown Secretary won Nobel Prizes. Additional information on previous Lasker Laureates can be found jordan u. gutterman, m.d. online at our web site http://www.laskerfoundation.org. Representative Albert Lasker Medical Research Awards Program Nominations that have been made in previous years may be updated and resubmitted in purnell w. choppin, m.d. accordance with the instructions on page 2 of this nomination booklet. daniel e. koshland, jr., ph.d. mrs. william mccormick blair, jr. the honorable mark o. hatfied Nominations should be received by the Foundation no later than February 2, 2004. Directors Emeritus A distinguished panel of jurors will select the scientists to be honored. The 2004 Albert Lasker Medical Research Awards will be presented at a luncheon ceremony given by the Foundation in New York City on Friday, October 1, 2004. Sincerely, Joseph L. Goldstein, M.D. Chairman, Awards Jury Albert Lasker Medical Research Awards ALBERT LASKER MEDICAL2004 RESEARCH AWARDS PURPOSE AND DESCRIPTION OF THE AWARDS The major purpose of these Awards is to recognize and honor individuals who have made signifi- cant contributions in basic or clinical research in diseases that are the main cause of death and disability. -
Years Because of a #Metoo Scandal
1 CHAPTERS 1 AWARDS & HONOURS 2 FAMOUS BOOKS 3 APPOINTMENTS 4 INDIAN ECONOMY 5 BUSINESS & CORPORATE WORLD 6 BRAND AMBASSADORS 7 AGREEMENTS & MoU 8 SUMMITS 9 INDEX, RANKINGS & DISTINCTIONS 10 SPORTS 11 SCIENCE & TECHNOLOGY 11 YOJANAS & SCHEMES 12 MISCELLANEOUS 2 AWARDS & HONOURS 2018 Nobel Laureates 2018 2018 Nobel Prize were announced in 5 different fields viz. Physiology or Medicine, Physics, Chemistry, Peace, & Economic Sciences. This is for the first time that Nobel Prize for Literature was not given in 70 years because of a #MeToo scandal. Field Winners Key Points “for their discovery of cancer James P Allison (USA) therapy by inhibition of negative Physiology or Medicine & Tasaku Honjo(Japan) immune regulation” Arthur Ashkin (USA), Gerard Mourou (France) and Donna Strickland "for groundbreaking inventions Physics (Canada) in the field of laser physics" (a) one half to Frances H. Arnold (USA) (a) "for the directed evolution of (b) Other half jointly to George P. enzymes" Chemistry Smith (USA) & Sir Gregory P. (b) "for the phage display of peptides & antibodies" Winter (UK) “for their efforts to end the use of Denis Mukwege (Congo) & sexual violence as a weapon of war Peace Nadia Murad (Iraq) & armed conflict” (a) “for integrating climate change into long-run macroeconomic analysis” (a) William D.Nordhaus (USA) Economic Sciences (b) “for integratingtechnological (b) Paul M. Romer (USA) innovations into long-run macroeconomic analysis.” 3 Ramon Magsaysay Award Winners 2018 Ramon Magsaysay Award is an annual award established to perpetuate former Philippine President Ramon Magsaysay's example of integrity in governance, courageous service to the people, & pragmatic idealism within a democratic society. -
Current Affairs August 2018 Pdf
CURRENT AFFAIRS AUGUST 2018 PDF AWARDS AND HONOURS Name of the Award Award Winner Additional Information Fields Medal Akshay Venkatesh Fields Medal is dubbed as the “Nobel prize for mathematics” Best performing primary HDFC Bank For the EWS (Economically lending institution in Credit Weaker Section) and LIG (Low Linked Subsidy Scheme (CLSS) Income Group) category Rajiv Gandhi Sadbhavana Former West Bengal Governor The award carries a citation Award 2018 Gopalkrishna Gandhi and a cash award of Rs.10 lakh. “Outstanding Parliamentarian” For 2013 - Dr Najma A. The Outstanding award Heptulla Parliamentarian Award was For 2014 - Hukumdev established in 1995. Narayan Yadav For 2015 - Congress leader Ghulam Nabi Azad, For 2016 - Dinesh Trivedi For 2017 - Bhartruhari Mahatab Top honours at the Swachhta Oil and Natural Gas Corp Indian Oil Corp (IOC) bagged Pakwada Awards (ONGC) the runner-up’s award. MasterChef Australia 2018 Indian origin prison guard Sashi Cheliah 100 women who changed the Marie Curie Poll conducted by BBC world Geography Bee World Indian-American high school Championship student Avi Goel Kotak Wealth Hurun-Leading Smitha V. Crishna Estimated wealth of ₹ 37,570 Wealthy Women 2018 list crore. Shaurya Chakra Rifleman Aurangzeb & - Major Aditya Kumar Vayu Sena Medal (Gallantry) Group Captain Abhishek Sharma, Squadron Leader Vernon Desmond Keane and Sergeant Shashidhar P Prasad 2018 Albany Medical Center James Allison, Carl June and Three US scientists Prize in Medicine and Steven Rosenberg Biomedical Research US Legion of Merit 2018 General Dalbir Singh Suhag The Legion of Merit is awarded in four degrees; Degree of Chief Commander, Degree of commander, Degree of the officer, Degree of Legionnarie. -
Targeting Glioblastoma Stem Cells Through Disruption of the Circadian Clock
Published OnlineFirst August 27, 2019; DOI: 10.1158/2159-8290.CD-19-0215 RESEARCH ARTICLE Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock Zhen Dong1, Guoxin Zhang1, Meng Qu2, Ryan C. Gimple1,3, Qiulian Wu1, Zhixin Qiu1, Briana C. Prager1,3, Xiuxing Wang1, Leo J.Y. Kim1,3, Andrew R. Morton3, Deobrat Dixit1, Wenchao Zhou4, Haidong Huang4, Bin Li5, Zhe Zhu1, Shideng Bao4, Stephen C. Mack6, Lukas Chavez7, Steve A. Kay2, and Jeremy N. Rich1 Downloaded from cancerdiscovery.aacrjournals.org on September 24, 2021. © 2019 American Association for Cancer Research. Published OnlineFirst August 27, 2019; DOI: 10.1158/2159-8290.CD-19-0215 ABSTRACT Glioblastomas are highly lethal cancers, containing self-renewing glioblastoma stem cells (GSC). Here, we show that GSCs, differentiated glioblastoma cells (DGC), and nonmalignant brain cultures all displayed robust circadian rhythms, yet GSCs alone displayed exquisite dependence on core clock transcription factors, BMAL1 and CLOCK, for optimal cell growth. Downregulation of BMAL1 or CLOCK in GSCs induced cell-cycle arrest and apoptosis. Chromatin immu- noprecipitation revealed that BMAL1 preferentially bound metabolic genes and was associated with active chromatin regions in GSCs compared with neural stem cells. Targeting BMAL1 or CLOCK attenu- ated mitochondrial metabolic function and reduced expression of tricarboxylic acid cycle enzymes. Small-molecule agonists of two independent BMAL1–CLOCK negative regulators, the cryptochromes and REV-ERBs, downregulated stem cell factors and reduced GSC growth. Combination of cryp- tochrome and REV-ERB agonists induced synergistic antitumor effi cacy. Collectively, these fi ndings show that GSCs co-opt circadian regulators beyond canonical circadian circuitry to promote stemness maintenance and metabolism, offering novel therapeutic paradigms. -
M-CL-24(Eng.)-C 1 P.T.O. B. A. (Hons.)/M.A. (ENGLISH) 1. The
B. A. (Hons.)/M.A. (ENGLISH) 1. The following are the events during India’s freedom struggle : 1. Chauri-Chaura Outrage 2. Minto-Morley Reforms 3. Dandi March 4. Montague-Chelmsford Reforms Arrange the chronological order of the events above. (A) 1-3-2-4 (B) 2-4-1-3 (C) 1-4-2-3 (D) 2-3-1-4 2. Which of the following is correctly matched ? (A) Do or die – Jawaharlal Nehru (B) Swaraj is my birthright – Mahatma Gandhi (C) Independence through non-violence must be our aim – Bal Gangadhar Tilak (D) Give me blood, I will give you freedom – Subhash Chandra Bose 3. The Wings of Fire : An Autobiography is written by : (A) Rajendra Prasad (B) A. P. J. Abdul Kalam (C) K. R. Narayanan (D) R. Venkatraman 4. Who said, “If it was proved to me that it (untouchability) is an essential part of Hinduism I for one would declare myself an open rebel against Hinduism itself” ? (A) B. R. Ambedkar (B) M. K. Gandhi (C) B. G. Tilak (D) Jyotiba Phule M-CL-24(Eng.)-C 1 P.T.O. 5. Match the following : List-I List-II 1. Rahul a. Buddha’s father 2. Alara Kalam b. Buddha’s cousin 3. Suddhodhana c. Buddha’s son 4. Devadatta d. The sage who taught mediation to Buddha 5. Siddharta e. Buddha’s original name (A) 1-a, 2-e, 3-d, 4-b, 5-c (B) 1-c, 2-d, 3-a, 4-b, 5-e (C) 1-e, 2-d, 3-b, 4-a, 5-c (D) 1-b, 2-a, 3-e, 4-d, 5-c 6. -
General Awareness–Current Affairs Month of October–2020
GENERAL AWARENESS–CURRENT AFFAIRS MONTH OF OCTOBER–2020 List of Important Days • October 01 - International Day for the Elderly. (Theme - “Pandemics: Do They Change How We Address Age and Ageing?”) • October 02 - International Day of Non-Violence. • October 02-08 - Wildlife Week. (Theme - “RoaR (Roar and Revive) – Exploring Human-Animal Relationships.”) • October 04 - World Animal Welfare Day. • October 04-10 - World Space Week. (Theme - “Satellites Improve Life.”) • October 05 - World Habitat Day. (Theme - “Housing for All-A better Urban Future”) • October 05 - World Teachers’ Day. (Theme - “Teachers: Leading in crisis, reimagining the future”) • October 07 - World Cotton Day. • October 08 - Indian Air Force Day. • October 09 - World Post Day. • October 10 - World Mental Health Day. • October 10 - World Migratory Bird Day. (Theme - “Birds Connect Our World”) • October 10 - National Postal Day. • October 11- International Day of the Girl Child. (Theme - “My voice, our equal future”) • October 12 - World Arthritis Day. • October 13 - International Day for Disaster Reduction. • October 14 - World Standards Day. (Theme - “Protecting the planet with standards”) • October 15 - World Students Day. (Theme - “Learning for people, prosperity and peace”) • October 15 - International Day of Rural Women. (Theme - “Building rural women’s resilience in the wake of COVID-19,”) • October 16 - World Food Day. (Theme - “Grow, Nourish, Sustain. Together”) • October 16 - 36th Raising Day of National Security Guard. • October 17 - International Day for the Eradication of Poverty. (Theme - “Acting together to achieve social and environmental justice for all”) • October 20 - World Osteoporosis Day. (Theme - “THAT’S OSTEOPOROSIS”) • October 20 - World Statistics Day. (Theme - “Connecting the world with data we can trust”) • October 20 - International Chefs Day.