Acacia Catechu 12 Acacia Nilotica 181 Acetyl-11-Keto-Β-Boswellic Acid

Total Page:16

File Type:pdf, Size:1020Kb

Acacia Catechu 12 Acacia Nilotica 181 Acetyl-11-Keto-Β-Boswellic Acid 438 Index A Azadirachta indica 6, 13, 120, 167, 187, 209 Azadiradione 29 Acacia catechu 12 Acacia nilotica 181 B acetyl-11-keto-β-boswellic acid (AKBA) 306-307 Bacopa monnieri 56 Achyranthes aspera 72 Baicalein 105-106 Aldactone 70 Baill 51, 99, 132 Allium sativum 12, 33, 74, 119, 209 Baldness 59 Aloe barbadensis 14, 51 Basil 9, 16, 79 Aloe vera 34, 51, 120, 178, 185, 209 Benincasa hispida 141, 218 Alopecia 50-52, 59 Berberine 10, 36, 101, 121 Amaranthus spinosus 52 Berberis aristata 16, 36, 121, 185 Amiloride 70 Bixa orellana 72 Amla 252 Black tea 82 Andrographis paniculata 16, 36, 164, 169 Blood purification 1, 3-4, 7-9, 12, 14-17 Andrographolide 36, 166, 169 Blood purifiers 7, 9-10, 14, 17 Anethum graveolens 34 Boerhavia diffusa 14 Annona squamosa 120 Boswellia serrata 302-303 Antioxidants 8-9, 34, 67, 74-81, 83, 122, Boswellic acid 302-307, 309-310 141, 250-253, 256-259, 261 Breast cancer 10, 91-96, 98, 272 Apigenin 32, 78 Bronchial asthma 307 Apium graveolens 34 Aromatherapy 51 C Ascorbic acid 17, 75-77, 252, 258, 261 Asiasari radix 57 Caffeoyl 78, 295 Asparagus racemosus 78 Camellia sinensis 35, 82 Astringent 1, 12, 73, 118, 187, 328 Capsicum 11 AuNPs 216-225 Caraway 80 Australian carbohydrate intolerance study Carica papaya 121 (ACHOIS) 28 Carnosic acid 78-79 Ayurveda 1-4, 6, 10-11, 13-14, 33, 52, 55, Carnosol 78 68, 72, 80, 116, 131, 136, 155, 164, Carotenoids 76-77, 119, 252-253, 256- 180-181, 188, 296, 317 257, 261 Index Carum carvi 77, 80 Emblica officinalis 16, 55 Catalase 75-76, 252, 291, 325-326 Epicatechin 82, 256 Catalpol 30 epigallo-catechin gallate (EGCG) 35 Catechin 79, 81-82, 256 Epirosmanol 78 Chaff flower 72 Eplerenone 70 Chemotherapy 5, 95-98, 106, 185, 323, 328 Estrogen receptor 91, 103 Chirata 9, 207 Eucalyptus 77, 81 Chlorthalidone 69 Eucalyptus globulus 81 Chronic cough 73 Eupatorium birmanicum 286-287 Cichorium intybus 14 Euphorbia thymifolia 73 Citrullus colocynthis 54 Citrus limon 13 F Cocculus hirsutus 80 Coleous forskohlii 218, 222 Fennel 79-80 Commiphora mukul 34 Ferulic acid 80 Common cress 71 Flatulence 73 Constipation 13, 17, 73, 116 Flavonoids 26, 34, 51, 53-56, 71, 77-80, 82, Coumarins 71, 79, 81-82, 130 99, 115-117, 119-120, 122, 141, 155, Crohn’s disease 302, 308, 310 164, 180, 207, 209, 222-223, 252-253, Cumin 79-81 255, 261, 289, 292-294, 325 Cuminum cyminum 77, 79 Foeniculum vulgare 77, 79 Curcubita pepo 218 Furosemide 69-74 Curcuma domestica 12 Curcuma longa 15, 33, 77, 80, 138, 208 G Curcumin 33, 80, 138, 166, 235-237, 239-245 Gallic acid 55, 81-82, 187, 253, 255-256 Custard apple 82, 120 Gallocatechin 82 Cyperus rotundus 103, 287 Ganoderma lucidum 8 Cyphostemma juttae 105 Garden cress 71 Garlic 12, 33, 74 D gestational diabetes mellitus (GDM) 28 Ginger 12, 57, 80, 119 Dandelion 73-74 Ginkgo biloba 58, 77, 81, 128, 133 Demulcent 73, 118 Ginsenosides 30, 59, 132 Devil’s horsewhip 72 Glutathione 75-77, 138, 240, 243-244, Diabetes mellitus 25-29, 34, 80, 116, 317 252, 319, 325 Diarrhea 12, 14, 16, 54, 59, 71, 73, 116-118, Glutathione peroxidase 75-76, 240, 252 180, 184-185, 187, 206, 289 Glutathione reductase 76-77, 252, 325 Diuretics 67-70, 83 Glycine max 35 Dyrenium 70 Glycorrhiza glabra 53 Dysentery 12, 73, 116-118, 132-133 good manufacturing practices (GMP) 271 Green synthesis 217-218 E Green tea 82 Guduchi 322 Eclipta alba 58 Gum 2, 12, 52, 119-122, 302-305, 307-310 Ellagic acid 81 439 Index H Malva crispa 218 Mangifera indica 70 Haemostatic 187 MAPK pathway 101 Hair loss 49-51, 53-54, 59-60, 98 Matricaria chamomilla 77, 81 Halim 71 Mentha officinalis 79 Hemidesmus indicus 15, 186 Mentha spicata 79 Hibiscus rosa-sinensis 52, 55, 101, 223 Metastasis 92, 95-97, 103 Hydrastis canadensis 10 Metolazone 69 Hydrate 81 Microzide 69 Hydrochlorothiazide 69, 72 Miglitol 29 Hydroxyl radicals 80 Mimosa pudica 71 Hyperlipidemia 31-32 Mint 79 Momordica charantia 29 I MTT assay 101 Murraya koenigii 136 Immunotherapy 97-98 Indapamide 69 N Indian ginseng 80, 104 Indian Traditional system of medicine 32 Nardostachys jatamansi 52, 130 Inspra 70 Naringenin 102 insulin dependent diabetes mellitus (IDDM) Nausea 80, 98, 132-133, 156 27 Neem 6, 168, 209 Insulin resistance 26-30, 36, 242 non-insulin dependent diabetes mellitus invalid metabolic panaceas (IMPs) 235, (NIDDM) 27 244-245 Isorosmanol 78 O L Ocimum basilicum 9, 77-78, 218 Olibanum 303 Langthrei 286-287 Oregon grape root 10 Larrea tridentate 9 Origanum vulgare 78 Laxative 14, 17, 71, 73, 118, 180, 185, 207 Oxidative stress 76, 79, 101, 104, 129, Lemon 13 241-242, 252, 319, 322 Lepidium sativum 71 Lily of desert 14 P Lipschitz method 72 Lithospermum erythrorhizon 102 pan-assay interference compounds (PAINS) Lonicera japonica 225 244 Loop diuretics 69 Paronychia 73 Luteolin 56, 78 PARP inhibitors 97 Persian cumin 80 M Phenolic acids 78-79, 115, 253, 255, 294 Phenolic diterpenes 78 Madhuca indica 14 Physcomitrella patens 269 Mahonia aquifolium 10 Phytolacca americana 10 Maidenhair tree 81 Plantago ovata 35 Malignant 92 Potassium-sparing diuretics 70 440 Index Progesterone receptor 91 Stimulant 12, 73, 118, 134, 136 Psoralea corylifolia 16 Superoxide dismutase 76, 240 Punarnava 14 Swertia chirata 9, 207 Q T Quercetin 55-56, 81, 122, 294 Tabebuia impetiginosa 11 Tannins 53, 55, 76, 115-117, 120, 122, 155, R 207, 210, 222, 249, 251-253, 255-256, 289, 318, 325 Reactive oxygen species 75-76, 101, 104, Taraxacum officinal 8, 73 129, 141, 250-251, 325 Terminalia chebula 187 Red clover 9 Thiazides 69 Resin 120-122, 302-310 Thinopyrum intermedium 11 Rosemary 56-57, 78 Thyme 78 Rosmanol 78 Thymus vulgaris 77-78 Rosmarinic acid 57, 78 Tinospora cordifolia 15, 140, 316-317, 322 Rosmarinus officinalis 51, 56, 78 TNBC 91-92, 94-97, 101-106 Rubefacient 71, 74, 118 Tocopherols 75, 78, 252 Rubia cordifolia 10 Torsemide 69 Rumex crispus 10 Traditional Chinese medicine 1-2, 4, 8, Rutin 81, 122, 289, 293 59, 155 Traditional Korean medicine 1-3 S Triamterene 70 Trifolium pretense 9 Saccharum officinarum 13 Triple negative breast cancer 91, 94 Saponins 7, 15, 32, 51, 53, 56, 78, 115- Tulsi 16, 184 117, 120, 122, 130, 132, 141, 210, Tumor 92, 97, 257, 272, 276, 292, 306 220, 289, 325 Turbinaria conoides 220 Schisandra chinensis 99, 137 Turmeric 12, 16, 80, 138, 235-237, 239, Secondary diabetes 28-29 241-242 Secondary metabolites 1, 75-77, 115, Type-2 diabetes mellitus (T2D) 27 117, 155-156, 166, 235, 253, 269, 271-272, 303 U Sedative 73, 137, 184, 309, 319 Shatavarin 78 Unani 1-4, 6, 10, 13, 17, 68, 80, 155, 167, Siddha 4, 68, 72, 80, 155, 164 296, 317 Silybum marianum 36 Urtica dioica 51, 54 Sitaphal 82 Smilax china 15 V Sophora flavescens 59, 101 Soy 35, 252 Vitamin-C 16, 258, 319 Spironolactone 70 Voglibose 29 Stephania tetrandra 106 441 Index W Y White tea 82 Yellow tea 82 Withaferin-A 104 Withania somnifera 6, 80, 104 Z Zingiber officinale 77, 80 442.
Recommended publications
  • Identification and Characterization of Phenolics from Ethanolic Extracts of Phyllanthus Species by HPLC-ESI-QTOF-MS/MS
    Author’s Accepted Manuscript Identification and characterization of phenolics from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS Sunil Kumar, Awantika Singh, Brijesh Kumar www.elsevier.com/locate/jpa PII: S2095-1779(17)30016-3 DOI: http://dx.doi.org/10.1016/j.jpha.2017.01.005 Reference: JPHA347 To appear in: Journal of Pharmaceutical Analysis Received date: 25 June 2016 Revised date: 13 January 2017 Accepted date: 17 January 2017 Cite this article as: Sunil Kumar, Awantika Singh and Brijesh Kumar, Identification and characterization of phenolics from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS, Journal of Pharmaceutical Analysis, http://dx.doi.org/10.1016/j.jpha.2017.01.005 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Identification and characterization of phenolics from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS Sunil Kumara, Awantika Singha,b, Brijesh Kumara,b* aSophisticated Analytical Instrument Facility, CSIR-Central Drug Research Institute, Lucknow- 226031, Uttar Pradesh, India bAcademy of Scientific and Innovative Research (AcSIR), New Delhi-110025, India [email protected] [email protected] *Corresponding author at: Sophisticated Analytical Instrument Facility, CSIR-Central Drug Research Institute, Lucknow-226031.
    [Show full text]
  • Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson's Disease: a Comparative Study
    antioxidants Article Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson’s Disease: A Comparative Study Lyubka P. Tancheva 1,*, Maria I. Lazarova 2 , Albena V. Alexandrova 3, Stela T. Dragomanova 1,4, Ferdinando Nicoletti 5 , Elina R. Tzvetanova 3, Yordan K. Hodzhev 6, Reni E. Kalfin 2, Simona A. Miteva 1, Emanuela Mazzon 7 , Nikolay T. Tzvetkov 8 and Atanas G. Atanasov 2,9,10,11,* 1 Department of Behavior Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria; [email protected] (S.T.D.); [email protected] (S.A.M.) 2 Department of Synaptic Signaling and Communications, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria; [email protected] (M.I.L.); reni_kalfi[email protected] (R.E.K.) 3 Department Biological Effects of Natural and Synthetic Substances, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria; [email protected] (A.V.A.); [email protected] (E.R.T.) 4 Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University, Varna 9002, Bulgaria 5 Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 89, 95123 Catania, Italy; [email protected] 6 Department of Sensory Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria; [email protected] 7 IRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy; [email protected] 8 Department of Biochemical
    [Show full text]
  • Prevention of Hormonal Mammary Carcinogenesis in Rats by Dietary Berries and Ellagic Acid
    University of Kentucky UKnowledge University of Kentucky Doctoral Dissertations Graduate School 2007 PREVENTION OF HORMONAL MAMMARY CARCINOGENESIS IN RATS BY DIETARY BERRIES AND ELLAGIC ACID Harini Sankaran Aiyer University of Kentucky, [email protected] Right click to open a feedback form in a new tab to let us know how this document benefits ou.y Recommended Citation Aiyer, Harini Sankaran, "PREVENTION OF HORMONAL MAMMARY CARCINOGENESIS IN RATS BY DIETARY BERRIES AND ELLAGIC ACID" (2007). University of Kentucky Doctoral Dissertations. 508. https://uknowledge.uky.edu/gradschool_diss/508 This Dissertation is brought to you for free and open access by the Graduate School at UKnowledge. It has been accepted for inclusion in University of Kentucky Doctoral Dissertations by an authorized administrator of UKnowledge. For more information, please contact [email protected]. ABSTRACT OF DISSERTATION Harini Sankaran Aiyer The Graduate School University of Kentucky 2007 PREVENTION OF HORMONAL MAMMARY CARCINOGENESIS IN RATS BY DIETARY BERRIES AND ELLAGIC ACID ABSTRACT OF DISSERTATION A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Nutritional Sciences at the University of Kentucky By Harini Sankaran Aiyer Louisville, Kentucky Director: Dr. Ramesh C.Gupta, Professor of Preventive Medicine Lexington, Kentucky 2007 Copyright © Harini Sankaran Aiyer, 2007 . ABSTRACT OF DISSERTATION PREVENTION OF HORMONAL MAMMARY-CARCINOGENESIS IN RATS BY DIETARY BERRIES AND ELLAGIC ACID. Breast cancer is the most frequently diagnosed cancer among women around the world. The hormone 17ß-estradiol (E2) is strongly implicated as a causative agent in this cancer. Since estrogen acts as a complete carcinogen, agents that interfere with the carcinogenic actions of E2 are required.
    [Show full text]
  • "Ellagic Acid, an Anticarcinogen in Fruits, Especially in Strawberries: a Review"
    FEATURE Ellagic Acid, an Anticarcinogen in Fruits, Especially in Strawberries: A Review John L. Maasl and Gene J. Galletta2 Fruit Laboratory, U.S. Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705 Gary D. Stoner3 Department of Pathology, Medical College of Ohio, Toledo, OH 43699 The various roles of ellagic acid as an an- digestibility of natural forms of ellagic acid, Mode of inhibition ticarcinogenic plant phenol, including its in- and the distribution and organ accumulation The inhibition of cancer by ellagic acid hibitory effects on chemically induced cancer, or excretion in animal systems is in progress appears to occur through the following its effect on the body, occurrence in plants at several institutions. Recent interest in el- mechanisms: and biosynthesis, allelopathic properties, ac- lagic acid in plant systems has been largely a. Inhibition of the metabolic activation tivity in regulation of plant hormones, for- for fruit-juice processing and wine industry of carcinogens. For example, ellagic acid in- mation of metal complexes, function as an applications. However, new studies also hibits the conversion of polycyclic aromatic antioxidant, insect growth and feeding in- suggest that ellagic acid participates in plant hydrocarbons [e.g., benzo (a) pyrene, 7,12- hibitor, and inheritance are reviewed and hormone regulatory systems, allelopathic and dimethylbenz (a) anthracene, and 3-methyl- discussed in relation to current and future autopathic effects, insect deterrent princi- cholanthrene], nitroso compounds (e.g., N- research. ples, and insect growth inhibition, all of which nitrosobenzylmethylamine and N -methyl- N- Ellagic acid (C14H6O8) is a naturally oc- indicate the urgent need for further research nitrosourea), and aflatoxin B1 into forms that curring phenolic constituent of many species to understand the roles of ellagic acid in the induce genetic damage (Dixit et al., 1985; from a diversity of flowering plant families.
    [Show full text]
  • Formulation Strategies to Improve Oral Bioavailability of Ellagic Acid
    Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 7 April 2020 doi:10.20944/preprints202004.0100.v1 Peer-reviewed version available at Appl. Sci. 2020, 10, 3353; doi:10.3390/app10103353 Review Formulation strategies to improve oral bioavailability of ellagic acid Guendalina Zuccari 1,*, Sara Baldassari 1, Giorgia Ailuno 1, Federica Turrini 1, Silvana Alfei 1, and Gabriele Caviglioli 1 1 Department of Pharmacy, Università di Genova, 16147 Genova, Italy * Correspondence: [email protected]; Tel.: +39 010 3352627 Featured Application: An updated description of pursued approaches for efficiently resolving the low bioavailability issue of ellagic acid. Abstract: Ellagic acid, a polyphenolic compound present in fruits and berries, has recently been object of extensive research for its antioxidant activity, which might be useful for the prevention and treatment of cancer, cardiovascular pathologies, and neurodegenerative disorders. Its protective role justifies numerous attempts to include it in functional food preparations and in dietary supplements not only to limit the unpleasant collateral effects of chemotherapy. However, ellagic acid use as chemopreventive agent has been debated because of its poor bioavailability associated to low solubility, limited permeability, first pass effect, and interindividual variability in gut microbial transformations. To overcome these drawbacks, various strategies for oral administration including solid dispersions, micro-nanoparticles, inclusion complexes, self- emulsifying systems, polymorphs have been proposed. Here, we have listed an updated description of pursued micro/nanotechnological approaches focusing on the fabrication processes and the features of the obtained products, as well as on the positive results yielded by in vitro and in vivo studies in comparison to the raw material.
    [Show full text]
  • Estrogen Metabolism: Are We Assessing It Properly? Filomena Trindade, MD, MPH
    Estrogen Metabolism: Are We Assessing It Properly? Filomena Trindade, MD, MPH The views and opinions expressed herein are solely those of the presenter and do not necessarily represent those of Genova Diagnostics. Thus, Genova Diagnostics does not accept liability for consequences of any actions taken on the basis of the information provided. Michael Chapman, ND Medical Education Specialist - Asheville Filomena Trindade, MD, MPH Technical Issues & Clinical Questions Please type any technical issue or clinical question into either the “Chat” or “Questions” boxes, making sure to send them to “Organizer” at any time during the webinar. We will be compiling your clinical questions and answering as many as we can the final 15 minutes of the webinar. DISCLAIMER: Please note that any and all emails provided may be used for follow up correspondence and/or for further communication. Estrogen Metabolism: Are We Assessing It Properly? Filomena Trindade, MD, MPH The views and opinions expressed herein are solely those of the presenter and do not necessarily represent those of Genova Diagnostics. Thus, Genova Diagnostics does not accept liability for consequences of any actions taken on the basis of the information provided. Objectives • Understand the importance of estrogen metabolism with respect to cancer risk • Be able to devise a treatment plan for a pt with an unfavorable estrogen metabolism profile • Gain a basic understanding of the importance of methylation in estrogen metabolism, health promotion and cancer prevention • Learn to apply these
    [Show full text]
  • The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties
    molecules Review The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties Majid Tafrihi 1, Muhammad Imran 2, Tabussam Tufail 2, Tanweer Aslam Gondal 3, Gianluca Caruso 4,*, Somesh Sharma 5, Ruchi Sharma 5 , Maria Atanassova 6,*, Lyubomir Atanassov 7, Patrick Valere Tsouh Fokou 8,9,* and Raffaele Pezzani 10,11,* 1 Department of Molecular and Cell Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar 4741695447, Iran; [email protected] 2 University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54600, Pakistan; [email protected] (M.I.); [email protected] (T.T.) 3 School of Exercise and Nutrition, Deakin University, Victoria 3125, Australia; [email protected] 4 Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici (Naples), Italy 5 School of Bioengineering & Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India; [email protected] (S.S.); [email protected] (R.S.) 6 Scientific Consulting, Chemical Engineering, University of Chemical Technology and Metallurgy, 1734 Sofia, Bulgaria 7 Saint Petersburg University, 7/9 Universitetskaya Emb., 199034 St. Petersburg, Russia; [email protected] 8 Department of Biochemistry, Faculty of Science, University of Bamenda, Bamenda BP 39, Cameroon 9 Department of Biochemistry, Faculty of Science, University of Yaoundé, NgoaEkelle, Annex Fac. Sci., Citation: Tafrihi, M.; Imran, M.; Yaounde 812, Cameroon 10 Phytotherapy LAB (PhT-LAB), Endocrinology Unit, Department of Medicine (DIMED), University of Padova, Tufail, T.; Gondal, T.A.; Caruso, G.; Via Ospedale 105, 35128 Padova, Italy Sharma, S.; Sharma, R.; Atanassova, 11 AIROB, Associazione Italiana per la Ricerca Oncologica di Base, 35128 Padova, Italy M.; Atanassov, L.; Valere Tsouh * Correspondence: [email protected] (G.C.); [email protected] (M.A.); [email protected] (P.V.T.F.); Fokou, P.; et al.
    [Show full text]
  • PHARMACEUTICAL APPENDIX to the HARMONIZED TARIFF SCHEDULE Harmonized Tariff Schedule of the United States (2008) (Rev
    Harmonized Tariff Schedule of the United States (2008) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE Harmonized Tariff Schedule of the United States (2008) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 2 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. ABACAVIR 136470-78-5 ACIDUM GADOCOLETICUM 280776-87-6 ABAFUNGIN 129639-79-8 ACIDUM LIDADRONICUM 63132-38-7 ABAMECTIN 65195-55-3 ACIDUM SALCAPROZICUM 183990-46-7 ABANOQUIL 90402-40-7 ACIDUM SALCLOBUZICUM 387825-03-8 ABAPERIDONUM 183849-43-6 ACIFRAN 72420-38-3 ABARELIX 183552-38-7 ACIPIMOX 51037-30-0 ABATACEPTUM 332348-12-6 ACITAZANOLAST 114607-46-4 ABCIXIMAB 143653-53-6 ACITEMATE 101197-99-3 ABECARNIL 111841-85-1 ACITRETIN 55079-83-9 ABETIMUSUM 167362-48-3 ACIVICIN 42228-92-2 ABIRATERONE 154229-19-3 ACLANTATE 39633-62-0 ABITESARTAN 137882-98-5 ACLARUBICIN 57576-44-0 ABLUKAST 96566-25-5 ACLATONIUM NAPADISILATE 55077-30-0 ABRINEURINUM 178535-93-8 ACODAZOLE 79152-85-5 ABUNIDAZOLE 91017-58-2 ACOLBIFENUM 182167-02-8 ACADESINE 2627-69-2 ACONIAZIDE 13410-86-1 ACAMPROSATE
    [Show full text]
  • Endophytic Fungus, Chaetomium Globosum, Associated with Marine Green Alga, a New Source of Chrysin Siya Kamat, Madhuree Kumari, Kuttuvan Valappil Sajna & C
    www.nature.com/scientificreports OPEN Endophytic fungus, Chaetomium globosum, associated with marine green alga, a new source of Chrysin Siya Kamat, Madhuree Kumari, Kuttuvan Valappil Sajna & C. Jayabaskaran* The marine ecosystem is an extraordinary reserve of pharmaceutically important, bioactive compounds even in this “synthetic age”. Marine algae-associated endophytic fungi have gained prominence as an important source of bioactive compounds. This study was conducted on secondary metabolites of Chaetomium globosum-associated with marine green alga Chaetomorpha media from the Konkan coastline, India. Its ethyl acetate extract (CGEE) exhibited an IC50 value of 7.9 ± 0.1 µg/ mL on MCF-7 cells. CGEE exhibited G2M phase cell cycle arrest, ROS production and MMP loss in MCF-7 cells. The myco-components in CGEE contributing to the cytotoxicity were found by Gas Chromatography/Mass Spectrometry analyses. Chrysin, a dihydroxyfavone was one of the forty- six myco-components which is commonly found in honey, propolis and passionfower extracts. The compound was isolated and characterized as fungal chrysin using HPLC, UV–Vis spectroscopy, LC– MS, IR and NMR analyses by comparing with standard chrysin. The purifed compound exhibited an IC50 value of 49.0 ± 0.6 µM while that of standard chrysin was 48.5 ± 1.6 µM in MCF-7 cells. It induced apoptosis, G1 phase cell cycle arrest, MMP loss, and ROS production. This is the frst report of chrysin from an alternative source with opportunities for yield enhancement. Trough centuries, indigenous cultures around the globe have used and developed natural strategies to treat a myriad of illnesses. Tese distinct natural non-nutrient compounds are secondary metabolites that have garnered a lot of attention in the scientifc community1,2.
    [Show full text]
  • Direct Link to Fulltext
    DO PUNICALAGINS HAVE POSSIBLE IMPACT ON SECRETION OF STEROID HORMONES BY PORCINE OVARIAN GRANULOSA CELLS? Dagmara Packová, Adriana Kolesárová Address(es): Ing. Dagmara Packová, 1Slovak University of Agriculture, Faculty of Biotechnology and Food Sciences, Department of Animal Physiology, Tr. A. Hlinku 2, 949 76 Nitra, Slovak Republic. *Corresponding author: [email protected] doi: 10.15414/jmbfs.2016.5.special1.57-59 ARTICLE INFO ABSTRACT Received 4. 12. 2015 Punicalagin is a major component responsible for pomegranate's antioxidant properties. Punicalagin is the predominant ellagitannin of Revised 7. 1. 2016 Punica granatum and present in two isomeric forms; punicalagin α and β. Punicalagins are metabolised to ellagic acid (antioxidant) and Accepted 15. 1. 2016 microorganisms present in colon can metabolize ellagic acid to urolithins – each other substances could be responsible for effect on cell Published 8. 2. 2016 intracellular mechanism. The aim of our study was to observe the effect of punicalagins on secretion of steroids hormones – progesterone and 17β-estradiol. Ovarian granulosa cells were cultivated during 24h without (control group) and with various doses (0.01, 0.1, 1, 10 and 100 µg.ml-1) of pomegranate compounds – punicalagins. Steroid hormones progesterone and 17β-estradiol were Regular article evaluated by ELISA. Obtained results showed that the secretion of progesterone and 17β-estradiol by ovarian granulosa cells was not significantly (P≥0.05) influenced by punicalagins. In this pilot study no effects of punicalagins on porcine ovarian granulosa cells were found. Keywords: Progesterone, 17β-estradiol, granulosa cells, punicalagins, steroidogenesis INTRODUCTION Isolation of granulosa cells Punicalagins are ellagitannins in which gallagic and ellagic acid are linked to a Ovarian granulosa cells were used in this in vitro study.
    [Show full text]
  • Dr. Duke's Phytochemical and Ethnobotanical Databases List of Chemicals for Varicose Veins
    Dr. Duke's Phytochemical and Ethnobotanical Databases List of Chemicals for Varicose Veins Chemical Activity Count (+)-ALLOMATRINE 1 (+)-ALPHA-VINIFERIN 1 (+)-CATECHIN 7 (+)-EUDESMA-4(14),7(11)-DIENE-3-ONE 1 (+)-GALLOCATECHIN 2 (+)-HERNANDEZINE 1 (+)-ISOCORYDINE 1 (+)-PRAERUPTORUM-A 1 (+)-PSEUDOEPHEDRINE 1 (+)-SYRINGARESINOL 1 (-)-16,17-DIHYDROXY-16BETA-KAURAN-19-OIC 1 (-)-ACETOXYCOLLININ 1 (-)-ALPHA-BISABOLOL 2 (-)-ARGEMONINE 1 (-)-BETONICINE 1 (-)-BISPARTHENOLIDINE 1 (-)-BORNYL-CAFFEATE 2 (-)-BORNYL-FERULATE 2 (-)-BORNYL-P-COUMARATE 2 (-)-DICENTRINE 1 (-)-EPIAFZELECHIN 1 (-)-EPICATECHIN 3 (-)-EPICATECHIN-3-O-GALLATE 1 (-)-EPIGALLOCATECHIN 1 (-)-EPIGALLOCATECHIN-3-O-GALLATE 2 (-)-EPIGALLOCATECHIN-GALLATE 3 (-)-HYDROXYJASMONIC-ACID 1 Chemical Activity Count (-)-N-(1'-DEOXY-1'-D-FRUCTOPYRANOSYL)-S-ALLYL-L-CYSTEINE-SULFOXIDE 1 (1'S)-1'-ACETOXYCHAVICOL-ACETATE 2 (15:1)-CARDANOL 1 (2R)-(12Z,15Z)-2-HYDROXY-4-OXOHENEICOSA-12,15-DIEN-1-YL-ACETATE 1 (7R,10R)-CAROTA-1,4-DIENALDEHYDE 1 (E)-4-(3',4'-DIMETHOXYPHENYL)-BUT-3-EN-OL 2 1,2,6-TRI-O-GALLOYL-BETA-D-GLUCOSE 1 1,7-BIS(3,4-DIHYDROXYPHENYL)HEPTA-4E,6E-DIEN-3-ONE 1 1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)-1,6-HEPTADIEN-3,5-DIONE 1 1,7-BIS-(4-HYDROXYPHENYL)-1,4,6-HEPTATRIEN-3-ONE 1 1,8-CINEOLE 3 1-(METHYLSULFINYL)-PROPYL-METHYL-DISULFIDE 1 1-O-(2,3,4-TRIHYDROXY-3-METHYL)-BUTYL-6-O-FERULOYL-BETA-D-GLUCOPYRANOSIDE 1 10-ACETOXY-8-HYDROXY-9-ISOBUTYLOXY-6-METHOXYTHYMOL 2 10-DEHYDROGINGERDIONE 1 10-GINGERDIONE 1 11-HYDROXY-DELTA-8-THC 1 11-HYDROXY-DELTA-9-THC 1 12,118-BINARINGIN 1 12-ACETYLDEHYDROLUCICULINE
    [Show full text]
  • Pomegranate As a Potential Alternative of Pain Management: a Review
    plants Review Pomegranate as a Potential Alternative of Pain Management: A Review José Antonio Guerrero-Solano 1, Osmar Antonio Jaramillo-Morales 1,* , Claudia Velázquez-González 1, Minarda De la O-Arciniega 1 , Araceli Castañeda-Ovando 2 , Gabriel Betanzos-Cabrera 3 and Mirandeli Bautista 1,* 1 Academic Area of Pharmacy, Institute of Health Sciences, Autonomous University of the State of Hidalgo, Mexico, San Agustin Tlaxiaca, Hidalgo 42160, Mexico; [email protected] (J.A.G.-S.); [email protected] (C.V.-G.); [email protected] (M.D.l.O.-A.) 2 Academic Area of Food Chemistry, Institute of Basic Sciences and Engineering, Autonomous University of the State of Hidalgo, Mexico, Pachuca- Tulancingo km 4.5 Carboneras, Pachuca de Soto, Hidalgo 42184, Mexico; [email protected] 3 Academic Area of Nutrition, Institute of Health Sciences, Autonomous University of the State of Hidalgo, Mexico, San Agustin Tlaxiaca, Hidalgo 42160, Mexico; [email protected] * Correspondence: [email protected] (O.A.J.-M.); [email protected] (M.B.) Received: 2 March 2020; Accepted: 27 March 2020; Published: 30 March 2020 Abstract: The use of complementary medicine has recently increased in an attempt to find effective alternative therapies that reduce the adverse effects of drugs. Punica granatum L. (pomegranate) has been used in traditional medicine for different kinds of pain. This review aims to explore the scientific evidence about the antinociceptive effect of pomegranate. A selection of original scientific articles that accomplished the inclusion criteria was carried out. It was found that different parts of pomegranate showed an antinociceptive effect; this effect can be due mainly by the presence of polyphenols, flavonoids, or fatty acids.
    [Show full text]