TNNC1 Antibody Cat. No.: 18-391
TNNC1 Antibody
Immunohistochemistry of paraffin-embedded human Immunofluorescence analysis of U2OS cells using TNNC1 colon carcinoma using TNNC1 antibody (18-391) at antibody (18-391). Blue: DAPI for nuclear staining. dilution of 1:100 (40x lens).
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of IMMUNOGEN: human TNNC1 (NP_003271.1).
TESTED APPLICATIONS: IF, IHC, WB
WB: ,1:500 - 1:2000
APPLICATIONS: IHC: ,1:50 - 1:200
IF: ,1:50 - 1:200
September 28, 2021 1 https://www.prosci-inc.com/tnnc1-antibody-18-391.html POSITIVE CONTROL: 1) Mouse heart
2) Mouse lung
3) Mouse skeletal muscle
PREDICTED MOLECULAR Observed: 16kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: TNNC1
TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, ALTERNATE NAMES: Troponin C, slow, Troponin C1, slow
GENE ID: 7134
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for BACKGROUND: tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 28, 2021 2 https://www.prosci-inc.com/tnnc1-antibody-18-391.html