TNNC1 Antibody Cat. No.: 18-391 TNNC1 Antibody Immunohistochemistry of paraffin-embedded human Immunofluorescence analysis of U2OS cells using TNNC1 colon carcinoma using TNNC1 antibody (18-391) at antibody (18-391). Blue: DAPI for nuclear staining. dilution of 1:100 (40x lens). Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of IMMUNOGEN: human TNNC1 (NP_003271.1). TESTED APPLICATIONS: IF, IHC, WB WB: ,1:500 - 1:2000 APPLICATIONS: IHC: ,1:50 - 1:200 IF: ,1:50 - 1:200 September 28, 2021 1 https://www.prosci-inc.com/tnnc1-antibody-18-391.html POSITIVE CONTROL: 1) Mouse heart 2) Mouse lung 3) Mouse skeletal muscle PREDICTED MOLECULAR Observed: 16kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: TNNC1 TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, ALTERNATE NAMES: Troponin C, slow, Troponin C1, slow GENE ID: 7134 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for BACKGROUND: tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 28, 2021 2 https://www.prosci-inc.com/tnnc1-antibody-18-391.html.