Fact Sheet: Vaccine-Derived Poliovirus
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Rotavirus Vaccine for the Prevention of Rotavirus Gastroenteritis Among Children
March 19, 1999 / Vol. 48 / No. RR-2 Recommendations and Reports Rotavirus Vaccine for the Prevention of Rotavirus Gastroenteritis Among Children Recommendations of the Advisory Committee on Immunization Practices (ACIP) Continuing Education Examination Education Continuing Inside: U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES Centers for Disease Control and Prevention (CDC) Atlanta, Georgia 30333 The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333. SUGGESTED CITATION Centers for Disease Control and Prevention. Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1999;48(No. RR-2):[inclu- sive page numbers]. Centers for Disease Control and Prevention....................Jeffrey P. Koplan, M.D., M.P.H. Director The material in this report was prepared for publication by National Center for Infectious Diseases.................................. James M. Hughes, M.D. Director Division of Viral and Rickettsial Diseases ................. Brian W. J. Mahy, Ph.D., Sc.D. Director National Immunization Program ...........................................Walter A. Orenstein, M.D. Director Epidemiology and Surveillance Division ...........................John R. Livengood, M.D. Director The production of this report as an MMWR serial publication was coordinated in Epidemiology Program Office.................................... Stephen B. Thacker, M.D., M.Sc. Director Office of Scientific and Health Communications ......................John W. Ward, M.D. Director Editor, MMWR Series Recommendations and Reports................................... Suzanne M. Hewitt, M.P.A. Managing Editor Valerie R. Johnson Project Editor Morie M. Higgins Visual Information Specialist Vol. 48 / No. RR-2 MMWR i Contents Clinical and Epidemiologic Features of Rotavirus Disease............................................. -
For Schools and Parents: K-12 Immunization Requirements
FOR SCHOOLS AND PARENTS: K-12 IMMUNIZATION REQUIREMENTS NJ Department of Health (NJDOH) Vaccine Preventable Disease Program Summary of NJ School Immunization Requirements Listed in the chart below are the minimum required number of doses your child must have to attend a NJ school.* This is strictly a summary document. Exceptions to these requirements (i.e. provisional admission, grace periods, and exemptions) are specified in the Immunization of Pupils in School rules, New Jersey Administrative Code (N.J.A.C. 8:57-4). Please reference the administrative rules for more details https://www.nj.gov/health/cd/imm_requirements/acode/. Additional vaccines are recommended by Advisory Committee on Immunization Practices (ACIP) for optimal protection. For the complete ACIP Recommended Immunization Schedule, please visit http://www.cdc.gov/vaccines/schedules/index.html. Minimum Number of Doses for Each Vaccine Grade/level child DTaP Polio MMR Varicella Hepatitis Meningococcal Tdap enters school: Diphtheria, Tetanus, acellular Pertussis Inactivated (Measles, (Chickenpox) B (Tetanus, Polio Vaccine Mumps, diphtheria, (IPV) Rubella) acellular pertussis) § | Kindergarten – A total of 4 doses with one of these doses A total of 3 2 doses 1 dose 3 doses None None 1st grade on or after the 4th birthday doses with one OR any 5 doses† of these doses given on or after the 4th birthday ‡ OR any 4 doses nd th † 2 – 5 grade 3 doses 3 doses 2 doses 1 dose 3 doses None See footnote NOTE: Children 7 years of age and older, who have not been previously vaccinated with the primary DTaP series, should receive 3 doses of Td. -
Attenuation of Human Respiratory Syncytial Virus by Genome-Scale Codon-Pair Deoptimization
Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization Cyril Le Nouëna,1, Linda G. Brocka, Cindy Luongoa, Thomas McCartya, Lijuan Yanga, Masfique Mehedia, Eckard Wimmerb,1, Steffen Muellerb,2, Peter L. Collinsa, Ursula J. Buchholza,3, and Joshua M. DiNapolia,3,4 aRNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and bDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794 Contributed by Eckard Wimmer, June 18, 2014 (sent for review February 14, 2014) Human respiratory syncytial virus (RSV) is the most important viral acid coding is unaffected, CPD strains provide the same reper- agent of serious pediatric respiratory-tract disease worldwide. A toire of epitopes for inducing cellular and humoral immunity as vaccine or generally effective antiviral drug is not yet available. the WT pathogen. Recently, the CPD approach has been used We designed new live attenuated RSV vaccine candidates by successfully to attenuate poliovirus, influenza A virus, Strepto- codon-pair deoptimization (CPD). Specifically, viral ORFs were recoded coccus pneumonia, and HIV type 1 (5, 10–13). by rearranging existing synonymous codons to increase the content In the present work, four CPD RSV genomes were designed, of underrepresented codon pairs. Amino acid coding was com- synthesized, and recovered by reverse genetics. The CPD pletely unchanged. Four CPD RSV genomes were designed in recombinant (r) RSVs were attenuated and temperature- which the indicated ORFs were recoded: Min A (NS1, NS2, N, P, sensitive in vitro. Furthermore, we demonstrated that the CPD M, and SH), Min B (G and F), Min L (L), and Min FLC (all ORFs except rRSVs were attenuated and immunogenic in mice and African M2-1 and M2-2). -
Polio Vaccine May Be Given at the Same Time As Other Paralysis (Can’T Move Arm Or Leg)
POLIO VVPOLIO AAACCINECCINECCINE (_________ W H A T Y O U N E E D T O K N O W ) (_I111 ________What is polio? ) (_I ________Who should get polio ) 333 vaccine and when? Polio is a disease caused by a virus. It enters a child’s (or adult’s) body through the mouth. Sometimes it does IPV is a shot, given in the leg or arm, depending on age. not cause serious illness. But sometimes it causes Polio vaccine may be given at the same time as other paralysis (can’t move arm or leg). It can kill people who vaccines. get it, usually by paralyzing the muscles that help them Children breathe. Most people should get polio vaccine when they are Polio used to be very common in the United States. It children. Children get 4 doses of IPV, at these ages: paralyzed and killed thousands of people a year before we 333 A dose at 2 months 333 A dose at 6-18 months had a vaccine for it. 333 A dose at 4 months 333 A booster dose at 4-6 years 222 Why get vaccinated? ) Adults c I Most adults do not need polio vaccine because they were Inactivated Polio Vaccine (IPV) can prevent polio. already vaccinated as children. But three groups of adults are at higher risk and should consider polio vaccination: History: A 1916 polio epidemic in the United States killed (1) people traveling to areas of the world where polio is 6,000 people and paralyzed 27,000 more. In the early common, 1950’s there were more than 20,000 cases of polio each (2) laboratory workers who might handle polio virus, and year. -
Swine Flu and Polio Vaccines: Some Parallels and Some Differences
Swine Fluand Polio Vaccines: Some Parallelsand Some Differences Howard B. Baumel College of Staten Island of the City Universityof New York Staten Island 10301 The swine flu vaccinationprogram vaccine could be successfullydevel- facturedby a single pharmaceutical generated debate in scientific and oped. company.The cause of this outbreak medical circlesthat extended to the Salkrelied heavily on his previous was never clearly established. Be- Downloaded from http://online.ucpress.edu/abt/article-pdf/39/9/550/36038/4446085.pdf by guest on 29 September 2021 general public.The controversythat experience as he attemptedto pro- cause bottles of tissue culture fluid centered on the vaccine's effective- duce a killedvirus polio vaccine.He containingthe virushad been stored ness and safety was reminiscentof used formalinto kill the virus and priorto being treated with formalin, the problemsthat accompaniedthe isolated one strain for each of the it was possiblethat bits of tissue had development of the polio vaccine three knowntypes of polio virus.To settled to the bottom covering the years ago. A review of that earlier determineif any live virusremained viruses and protecting them from scientific achievement can provide after the exposure to formalin,the the formalin.To prevent this, the insightsinto the swineflu dilemma. treated virus was injected into the tissue culture fluid was filtered to By the mid-1930's,only threeviral brain of a monkey. If the monkey remove the debris before exposure diseases,smallpox, rabies, and yellow contracted polio, it was concluded to formalin. fever, had yielded to vaccines. In that live viruswas present.To deter- HeraldCox and HilaryKoprowski each of these cases, the vaccine mine if the treated virus was effec- (1955, 1956) had developed an consisted of a live virus. -
Polio Fact Sheet
Polio Fact Sheet 1. What is Polio? - Polio is a disease caused by a virus that lives in the human throat and intestinal tract. It is spread by exposure to infected human stool: e.g. from poor sanitation practices. The 1952 Polio epidemic was the worst outbreak in the nation's history. Of nearly 58,000 cases reported that year, 3,145 people died and 21,269 were left with mild to disabling paralysis, with most of the victims being children. The "public reaction was to a plague", said historian William O'Neill. "Citizens of urban areas were to be terrified every summer when this frightful visitor returned.” A Polio vaccine first became available in 1955. 2. What are the symptoms of Polio? - Up to 95 % of people infected with Polio virus are not aware they are infected, but can still transmit it to others. While some develop just a fever, sore throat, upset stomach, and/or flu-like symptoms and have no paralysis or other serious symptoms, others get a stiffness of the back or legs, and experience increased sensitivity. However, a few develop life-threatening paralysis of muscles. The risk of developing serious symptoms increases with the age of the ill person. 3. Is Polio still a disease seen in the United States? - The last naturally occurring cases of Polio in the United States were in 1979, when an outbreak occurred among the Amish in several states including Pennsylvania. 4. What kinds of Polio vaccines are used in the United States? - There is now only one kind of Polio vaccine used in the United States: the Inactivated Polio vaccine (IPV) is given as an injection (shot). -
Hepatitis B Vaccine – Frequently Asked Questions (Information from the CDC)
AAMC Standardized Immunization Form 2020 Hepatitis B Vaccine – Frequently Asked Questions (Information from the CDC) 1. What are the hepatitis B vaccines licensed for use in the United States? Three single-antigen vaccines and two combination vaccines are currently licensed in the United States. Single-antigen hepatitis B vaccines: • ENGERIX-B® • RECOMBIVAX HB® • HEPLISAV-B™ Combination vaccines: • PEDIARIX®: Combined hepatitis B, diphtheria, tetanus, acellular pertussis (DTaP), and inactivated poliovirus (IPV) vaccine. Cannot be administered before age 6 weeks or after age 7 years. • TWINRIX®: Combined Hepatitis A and hepatitis B vaccine. Recommended for people aged ≥18 years who are at increased risk for both HAV and HBV infections. 2. What are the recommended schedules for hepatitis B vaccination? The vaccination schedule most often used for children and adults is three doses given at 0, 1, and 6 months. Alternate schedules have been approved for certain vaccines and/or populations. A new formulation, Heplisav-B (HepB-CpG), is approved to be given as two doses one month apart. 3. If there is an interruption between doses of hepatitis B vaccine, does the vaccine series need to be restarted? No. The series does not need to be restarted but the following should be considered: • If the vaccine series was interrupted after the first dose, the second dose should be administered as soon as possible. • The second and third doses should be separated by an interval of at least 8 weeks. • If only the third dose is delayed, it should be administered as soon as possible. 4. Is it harmful to administer an extra dose of hepatitis B vaccine or to repeat the entire vaccine series if documentation of the vaccination history is unavailable or the serology test is negative? No, administering extra doses of single-antigen hepatitis B vaccine is not harmful. -
Wastewater Based Epidemiology Perspective As a Faster Protocol for Detecting Coronavirus RNA in Human Populations: a Review with Specific Reference to SARS-Cov-2 Virus
pathogens Review Wastewater Based Epidemiology Perspective as a Faster Protocol for Detecting Coronavirus RNA in Human Populations: A Review with Specific Reference to SARS-CoV-2 Virus Milad Mousazadeh 1,2,†,‡ , Razieh Ashoori 3, Biswaranjan Paital 4 , I¸sıkKabda¸slı 5,‡ , Zacharias Frontistis 6 , Marjan Hashemi 7 , Miguel A. Sandoval 8,9,‡ , Samendra Sherchan 10, Kabita Das 11 and Mohammad Mahdi Emamjomeh 12,* 1 Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran; [email protected] 2 Department of Environmental Health Engineering, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran 3 Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran; [email protected] 4 Redox Regulation Laboratory, College of Basic Science and Humanities, Odisha University of Agriculture and Technology, Bhubaneswar 751003, India; [email protected] 5 Environmental Engineering Department, Civil Engineering Faculty, Ayaza˘gaCampus, Istanbul˙ Technical University, Istanbul˙ 34469, Turkey; [email protected] 6 Department of Chemical Engineering, University of Western Macedonia, 50132 Kozani, Greece; Citation: Mousazadeh, M.; Ashoori, [email protected] 7 Environmental and Occupational Hazards Control Research Center, Shahid Beheshti University of Medical R.; Paital, B.; Kabda¸slı,I.; Frontistis, Sciences, Tehran, Iran; [email protected] Z.; Hashemi, M.; Sandoval, M.A.; 8 Laboratorio de Electroquímica Medio Ambiental LEQMA, Departamento -
Preventing Polio WHO Myanmar Newsletter Special , 5 August 2019
Preventing polio WHO Myanmar newsletter special , 5 August 2019 What is polio? Poliomyelitis (polio) is a highly infectious disease that is caused when the polio virus invades the nervous system of an infected person. Polio can cause paralysis and even death. Who is most at risk for polio? Poliovirus usually affects children under 5 years of age who are unvaccinated or under-vaccinated. The virus can also affect or be carried by adolescents and adults. photo credit: Ms Lei Lei Mon, WHO Myanmar The child or individual suspected of polio may A child receives oral polio vaccine at Thandaung township, complain of sudden onset of weakness of arms Kayin State, 21 July 2019 and/or legs. Oral polio vaccine is the vaccine Is there a cure for polio? recommended for polio eradication Can it be prevented? There is no cure for polio. The disease can severely paralyze, or even kill, an infected child. Is the polio vaccine safe? Oral polio vaccine is one of the safest vaccines Polio can be prevented by immunizing a child with ever developed. It is so safe it can be given to sick approrpiate vaccination. There are currently two children and newborns. Since 1961, when oral effective polio vaccines, the inactivated poliovirus polio vaccine was introduced, two billion children vaccine (IPV) and the live attenuated oral polio have been immunized against polio globally. vaccine (OPV). This is estimated to have saved at least 16 million children from permanent paralysis by polio, world- wide. It is also safe to administer multiple doses of polio vaccine to children. -
2021-22 School Year New York State Immunization Requirements for School Entrance/Attendance1
2021-22 School Year New York State Immunization Requirements for School Entrance/Attendance1 NOTES: Children in a prekindergarten setting should be age-appropriately immunized. The number of doses depends on the schedule recommended by the Advisory Committee on Immunization Practices (ACIP). Intervals between doses of vaccine should be in accordance with the ACIP-recommended immunization schedule for persons 0 through 18 years of age. Doses received before the minimum age or intervals are not valid and do not count toward the number of doses listed below. See footnotes for specific information foreach vaccine. Children who are enrolling in grade-less classes should meet the immunization requirements of the grades for which they are age equivalent. Dose requirements MUST be read with the footnotes of this schedule Prekindergarten Kindergarten and Grades Grades Grade Vaccines (Day Care, 1, 2, 3, 4 and 5 6, 7, 8, 9, 10 12 Head Start, and 11 Nursery or Pre-k) Diphtheria and Tetanus 5 doses toxoid-containing vaccine or 4 doses and Pertussis vaccine 4 doses if the 4th dose was received 3 doses (DTaP/DTP/Tdap/Td)2 at 4 years or older or 3 doses if 7 years or older and the series was started at 1 year or older Tetanus and Diphtheria toxoid-containing vaccine Not applicable 1 dose and Pertussis vaccine adolescent booster (Tdap)3 Polio vaccine (IPV/OPV)4 4 doses 3 doses or 3 doses if the 3rd dose was received at 4 years or older Measles, Mumps and 1 dose 2 doses Rubella vaccine (MMR)5 Hepatitis B vaccine6 3 doses 3 doses or 2 doses of adult hepatitis B vaccine (Recombivax) for children who received the doses at least 4 months apart between the ages of 11 through 15 years Varicella (Chickenpox) 1 dose 2 doses vaccine7 Meningococcal conjugate Grades 2 doses vaccine (MenACWY)8 7, 8, 9, 10 or 1 dose Not applicable and 11: if the dose 1 dose was received at 16 years or older Haemophilus influenzae type b conjugate vaccine 1 to 4 doses Not applicable (Hib)9 Pneumococcal Conjugate 1 to 4 doses Not applicable vaccine (PCV)10 Department of Health 1. -
2021 Medicare Vaccine Coverage Part B Vs Part D
CDPHP® Medicare Advantage Vaccine Coverage Guide Part B (Medical) vs. Part D (Pharmacy) Medicare Part B (Medical): Medicare Part D (Pharmacy): Vaccinations or inoculations Vaccinations or inoculations are included when the administration is (except influenza, pneumococcal, reasonable and necessary for the prevention of illness. and hepatitis B for members at risk) are excluded unless they are directly related to the treatment of an injury or direct exposure to a disease or condition. • Influenza Vaccine (Flu) • BCG Vaccine • Pneumococcal Vaccine • Diphtheria/Tetanus/Acellular Pertussis Vaccine (ADACEL, (Pneumovax, Prevnar 13) BOOSTRIX, DAPTACEL, INFANRIX) • Hepatitis B Vaccine • Diphtheria/Tetanus/Acellular Pertussis/Inactivated Poliovirus (Recombivax, Engerix-B) Vaccine (KINRIX, QUADRACEL) for members at moderate • Diphtheria/Tetanus Vaccine (DT, Td, TDVAX, TENIVAC) to high risk • Diphtheria/Tetanus/Acellular Pertussis/Inactivated Poliovirus Vac • Other vaccines when directly cine/ Haemophilus Influenzae Type B Conjugate Vaccine (PENTACEL) related to the treatment of an • Diphtheria/Tetanus/Acellular Pertussis/Inactivated Poliovirus injury or direct exposure to a Vaccine/Hepatitis B Vaccine (PEDIARIX) disease or condition, such as: • Haemophilus Influenzae Type B Conjugate Vaccine (ActHIB, PedvaxHIB, • Antivenom Sera Hiberix) • Diphtheria/Tetanus Vaccine • Hepatitis A Vaccine, Inactivated (VAQTA) (DT, Td, TDVAX, TENIVAC) • Hepatitis B Vaccine, Recombinant (ENGERIX-B, RECOMBIVAX HB) • Rabies Virus Vaccine for members at low risk (RabAvert, -
Vaccinations for Preteens and Teens, Age 11-19 Years
Vaccinations for Preteens and Teens, Age 11–19 Years Getting immunized is a lifelong, life-protecting job. Make sure you and your healthcare provider keep your immunizations up to date. Check to be sure you’ve had all the vaccinations you need. Vaccine Do you need it? Chickenpox Yes! If you haven’t been vaccinated and haven’t had chickenpox, you need 2 doses of this vaccine. (varicella; Var) Anybody who was vaccinated with only 1 dose should get a second dose. Hepatitis A Yes! If you haven’t been vaccinated, you need 2 doses of this vaccine. Anybody who was vaccinated (HepA) with only 1 dose should get a second dose at least 6–18 months later. Hepatitis B Yes! This vaccine is recommended for all people age 0–18 years. You need a hepatitis B vaccine series (HepB) if you have not already received it. Haemophilus influ- Maybe. If you haven’t been vaccinated against Hib and have a high-risk condition (such as a non- enzae type b (Hib) functioning spleen), you need this vaccine. Human Yes! All preteens need 2 doses of HPV vaccine at age 11 or 12. Older teens who haven't been vacci- papillomavirus nated will need 2 or 3 doses. This vaccine protects against HPV, a common cause of genital warts and (HPV) several types of cancer, including cervical cancer and cancer of the anus, penis, and throat. Influenza Yes! Everyone age 6 months and older needs annual influenza vaccination every fall or winter and (Flu) for the rest of their lives.