1 Food Mirrobiolog and There Have Been a Few Recorded Outbreaks As a Result of Fungal Contamination In
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Food Allergy • Higher Prevalence in Children: Many Food Allergic Children Develop Immune Tolerance Background Ctd
Overview of Food-Related Adverse Reactions ALLSA 2017 Dr Claudia Gray Dr Claudia Gray • MBChB, FRCPCH (London), MSc (Surrey), Dip Allergy (Southampton), DipPaedNutrition(UK), PhD (UCT) • Paediatrician and Allergologist, UCT Lung Institute • Red Cross Children’s Hospital Allergy and Asthma Department • [email protected] Background 1. Food allergies are common: • Infants: 6-10%; children 2-8%, adults 1-2% true food allergy • Higher prevalence in children: many food allergic children develop immune tolerance Background ctd 2. Food allergies are increasing: • Peanut allergy in UK doubled in 1-2 decades: 1.8%. ? Stabilising in some regions Background 3. Spectrum changing: • Multiple food allergies increasing • “Rare” food allergies are increasing e.g. Eosinophilic oesophagitis; FPIES Allergenic Foods • Prevalence of food allergies influenced by geography and diet; egg and milk allergy universally common • Relatively small number of food types cause the majority of reactions: Allergenic Foods Young Children Adults • Cow’s milk • Fin-fish • Hen’s Egg • Shellfish • Wheat • Treenut • Soya • Peanut • Peanut • Fruit and vegetables • Treenut • Sesame • Kiwi • (* persistence likely) Allergenic Foods • A single food allergen can induce a range of allergic reactions e.g. wheat Classification of Adverse reactions to Food Classification of adverse reactions to food Adverse Reaction to food May occur in all Occurs only in some individuals if they eat susceptible sufficient quantity individuals Pharma- Micro- Toxic Food Food (e.g. cological biological scromboid) e.g. e.g food aversion hypersensitivity tyramine poisoning Classification of adverse reactions to food Food Hypersensitivity Non-allergic food Food Allergy hypersensitivity Mixed IgE- Unknown Metabolic IgE- and non Non IgE- e.g. -
Copyrighted Material
Index INDEX Note: page numbers in italics refer to fi gures, those in bold refer to tables and boxes. abducens nerve 55 activity cycles 499–522 inhibition 485 absorption effi ciency 72 annual patterns 515, 516, 517–22 interactions 485–6 abyssal zone 393 circadian rhythms 505 prey 445 Acanthaster planci (Crown-of-Thorns Starfi sh) diel patterns 499, 500, 501–2, 503–4, reduction 484 579 504–7 aggressive mimicry 428, 432–3 Acanthocybium (Wahoo) 15 light-induced 499, 500, 501–2, 503–4, aggressive resemblance 425–6 Acanthodii 178, 179 505 aglomerular 52 Acanthomorpha 284–8, 289 lunar patterns 507–9 agnathans Acanthopterygii 291–325 seasonal 509–15 gills 59, 60 Atherinomorpha 293–6 semilunar patterns 507–9 osmoregulation 101, 102 characteristics 291–2 supra-annual patterns 515, 516, 517–22 phylogeny 202 distribution 349, 350 tidal patterns 506–7 ventilation 59, 60 jaws 291 see also migration see also hagfi shes; lampreys Mugilomorpha 292–3, 294 adaptive response 106 agnathous fi shes see jawless fi shes pelagic 405 adaptive zones 534 agonistic interactions 83–4, 485–8 Percomorpha 296–325 adenohypophysis 91, 92 chemically mediated 484 pharyngeal jaws 291 adenosine triphosphate (ATP) 57 sound production 461–2 phylogeny 292, 293, 294 adipose fi n 35 visual 479 spines 449, 450 adrenocorticotropic hormone (ACTH) 92 agricultural chemicals 605 Acanthothoraciformes 177 adrianichthyids 295 air breathing 60, 61–2, 62–4 acanthurids 318–19 adult fi shes 153, 154, 155–7 ammonia production 64, 100–1 Acanthuroidei 12, 318–19 death 156–7 amphibious 60 Acanthurus bahianus -
Histamine Poisoning Fact Sheet
Histamine Poisoning Fact Sheet What is Histamine? How much histamine is a harmful dose? Scombroid food poisoning is caused by A threshold dose is considered to be 90 mg/100 ingestion of histamine, a product of the g. Although, levels as low as 5-20 mg/ 100 g could degradation of the amino acid histidine. possibly be toxic; particularly in susceptible Histidine can be found freely in the muscles individuals. of some fish species and can be degraded to What are the symptoms? histamine by enzymatic action of some naturally occurring bacteria. Initial symptoms resemble some allergic reactions which include sweating, nausea, headache and tingling or peppery sensation in the mouth and Which types of fish can be implicated? throat. The scombrid fish such as tuna and mackerel are Other symptoms include urticarial rash (hives), traditionally considered to present the highest localised skin inflammation, vomiting, diarrhoea, risk. However, other species have also been abdominal cramps, flushing of the face and low associated with histamine poisoning; e.g. blood pressure. anchovies, sardines, Yellowtail kingfish, Amberjack and Australian salmon, Mahi Mahi and Severe symptoms include blurred vision, severe Escolar. respiratory distress and swelling of the tongue. Which bacteria are involved? What can be done to manage histamine in seafood? A variety of bacterial genera have implicated in the formation of histamine; e.g. Clostridium, • Histamine levels can increase over a wide Morganella, Pseudomonas, Photobacterium, range of storage temperatures. However, Brochothrix and Carnobacterium. histamine production is highest over 21.8 °C. Once the enzyme is present in the fish, it can What outbreaks have occurred? continue to produce histamine at refrigeration temperatures. -
Urticaria and Angioedema
Challenging Cases in Allergy and Immunology Massoud Mahmoudi Editor Challenging Cases in Allergy and Immunology Editor Massoud Mahmoudi D.O, Ph.D. RM (NRM), FACOI, FAOCAI, FASCMS, FACP, FCCP, FAAAAI Assistant Clinical Professor of Medicine University of California San Francisco San Francisco, California Chairman, Department of Medicine Community Hospital of Los Gatos Los Gatos, California USA ISBN 978-1-60327-442-5 e-ISBN 978-1-60327-443-2 DOI 10.1007/978-1-60327-443-2 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2009928233 © Humana Press, a part of Springer Science+Business Media, LLC 2009 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. -
Date: 1/9/2017 Question: Botulism Is an Uncommon Disorder Caused By
6728 Old McLean Village Drive, McLean, VA 22101 Tel: 571.488.6000 Fax: 703.556.8729 www.clintox.org Date: 1/9/2017 Question: Botulism is an uncommon disorder caused by toxins produced by Clostridium botulinum. Seven subtypes of botulinum toxin exist (subtypes A, B, C, D, E, F and G). Which subtypes have been noted to cause human disease and which ones have been reported to cause infant botulism specifically in the United States? Answer: According to the cited reference “Only subtypes A, B, E and F cause disease in humans, and almost all cases of infant botulism in the United States are caused by subtypes A and B. Botulinum-like toxins E and F are produced by Clostridium baratii and Clostridium butyricum and are only rarely implicated in infant botulism” (Rosow RK and Strober JB. Infant botulism: Review and clinical update. 2015 Pediatr Neurol 52: 487-492) Date: 1/10/2017 Question: A variety of clinical forms of botulism have been recognized. These include wound botulism, food borne botulism, and infant botulism. What is the most common form of botulism reported in the United States? Answer: According to the cited reference, “In the United States, infant botulism is by far the most common form [of botulism], constituting approximately 65% of reported botulism cases per year. Outside the United States, infant botulism is less common.” (Rosow RK and Strober JB. Infant botulism: Review and clinical update. 2015 Pediatr Neurol 52: 487-492) Date: 1/11/2017 Question: Which foodborne pathogen accounts for approximately 20 percent of bacterial meningitis in individuals older than 60 years of age and has been associated with unpasteurized milk and soft cheese ingestion? Answer: According to the cited reference, “Listeria monocytogenes, a gram-positive rod, is a foodborne pathogen with a tropism for the central nervous system. -
Processing Parameters Needed to Control Pathogens in Cold-Smoked Fish
Processing Parameters Needed to Control Pathogens in Cold-Smoked Fish A Report of the Institute of Food Technologists for the Food and Drug Administration of the U.S. Department of Health and Human Services submitted March 29, 2001 IFT/FDA Contract No. 223-98-2333 Task Order 2 Processing Parameters Needed to Control Pathogens in Cold-smoked Fish Table of Contents Preface ........................................................................ S-1058 7. Conclusions ....................................................................... S-1079 8. Research needs ................................................................. S-1079 Science Advisory Board .......................................... S-1058 References ............................................................................. S-1080 Scientific and Technical Panel ............................... S-1058 Chapter III. Potential Hazards in Cold-Smoked Fish: Clostridium botulinum type E Reviewers .................................................................. S-1058 Scope ...................................................................................... S-1082 1. Introduction ....................................................................... S-1082 Additional Acknowledgments ............................... S-1058 2. Prevalence in water, raw fish, and smoked fish .............. S-1083 3. Growth in refrigerated smoked fish ................................. S-1083 Background ...............................................................S-1059 4. Effect of processing -
Histamine (Scombroid
Histamine (Scombroid Poisioning) Fact Sheet What is Histamine? What are the symptoms? Initial symptoms resemble some allergic reactions, Scombroid food poisoning is caused by including sweating, nausea, headache and tingling ingestion of fish containing high or a peppery taste in the mouth and throat. concentrations of histamine, which is a Other symptoms include urticarial rash (hives), product of the degradation of the amino acid localised skin inflammation, vomiting, diarrhoea, histidine. Histidine can be found freely in the abdominal cramps, flushing of the face and low muscles of some fish species and can be blood pressure. degraded to histamine by enzymatic action of Severe symptoms include blurred vision, severe some naturally occurring bacteria. respiratory distress and swelling of the tongue. What can be done to manage histamine in Which types of fish can be implicated? seafood? The scombrid fish such as tuna and mackerel are Histamine levels can increase over a wide range traditionally considered to present the highest risk. of storage temperatures. However, histamine However, other species have also been associated production is highest over 21.8 °C. Once the with histamine poisoning; e.g. anchovies, sardines, enzyme is present in the fish, it can continue to Yellowtail kingfish, Amberjack, Australian salmon produce histamine at refrigeration and Mahi Mahi. temperatures. Which bacteria are involved? Preventing the degradation of histidine to A variety of bacterial genera have been implicated histamine by rapid chilling of fish immediately in the formation of histamine; e.g. Clostridium, after death, followed by good temperature Morganella, Pseudomonas, Photobacterium, control in the supply chain is the most Brochothrix and Carnobacterium. -
Gwilliam Michael
Assessing the role of the Benguela Current as a major biogeographic barrier to marine coastal fishes. Michael Gwilliam A thesis submitted to Aberystwyth University in partial fulfilment for the degree of Doctor of Philosophy. Institute of Biological, Environmental and Rural Sciences Aberystwyth University 2016 Declaration Word Count of thesis: 55,923 This work has not previously been accepted in substance for any degree and is not being concurrently submitted in candidature for any degree. Candidate name MICHAEL GWILLIAM Signature: Date 25/12/2016 STATEMENT 1 This thesis is the result of my own investigations, except where otherwise stated. Where *correction services have been used, the extent and nature of the correction is clearly marked in a footnote(s). Other sources are acknowledged by footnotes giving explicit references. A bibliography is appended. Signature: Date 25/12/2016 [*this refers to the extent to which the text has been corrected by others] STATEMENT 2 I hereby give consent for my thesis, if accepted, to be available for photocopying and for inter-library loan, and for the title and summary to be made available to outside organisations. Signature: Date 25/12/2016 2 Acknowledgements I would like to thank first and foremost my Supervisor Professor Paul Shaw and Dr Niall McKeown. They have both been of exceptional help in writing this thesis in what at times were not ideal circumstances for me. Additionally they have ensured I haven’t gone too far off the academic rails over the last few years. I would also like to thank the help of my colleagues in the Shaw Lab namely Dr Max Blake (soon to be Dr) and Amy Rainbow Unicorn Moonchild Healey for all their help and discussions during the last few years. -
Poisoning by Edible Fish
246 JAccid Emerg Med 1997;14:246-251 REVIEW J Accid Emerg Med: first published as 10.1136/emj.14.4.246 on 1 July 1997. Downloaded from Ichthyosarcotoxism: poisoning by edible fish Iain C Grant The term ichthyosarcotoxism describes a variety cause different syndromes, and even within a of conditions arising as the result of poisoning recognised single disease entity there may be by fish flesh. Poisoning by shellfish and other wide variation in symptoms depending on the invertebrates is excluded, as is bacterial food fish eaten or the geographical area. All of this poisoning from contaminated fish. Although makes classification very difficult and conse- most of the conditions are experienced mainly quently no recognised classification exists. in warmer climates than Britain's, one form of Table 1 shows an attempt to classify the condi- fish poisoning is relatively common here, and tions by the type of clinical features and symp- others may be imported, either through toms usually seen. This arrangement is simpli- imported fish or by travellers. The conditions fied and there is some overlap between could present to any accident and emergency conditions, but for the physician faced with a (A&E) department, and increased awareness patient with likely fish poisoning it gives some of these disease entities may improve diagnosis guidance towards a specific diagnosis. and management. It has been suggested that the features of It has long been known that some normally ciguatera, tetraodon, and paralytic shellfish edible fish species may from time to time cause poisoning are similar and that these should be poisoning. -
Seafood Poisoning Symptom, Treatment and Prevention
Borneo Journal of Marine Science and Aquaculture Volume: 02 | December 2018, 64 - 69 Seafood poisoning symptom, treatment and prevention Murtaza Mustafa1, Teruaki Yoshida2, Zarinah Waheed3, Mohd Yusof Ibrahim1, Mohammad Illzam Elahee4, Shahjee Hussain1, Sharifa Mariam Uma Abdullah5 and Mehvish Muhammad Hanif6 1Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, Malaysia 2Harmful Algal Blooms Research Unit, Borneo Marine Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia. 3Endangered Marine Species Research Unit, Borneo Marine Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia. 4Polyclinic Sihat, Likas, Kota Kinabalu, Sabah, Malaysia 5Quality Unit, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia. 6Department of Zoology, Wildlife and Fisheries, Agriculture University, Faisalabad, Pakistan. *Corresponding author: [email protected] Abstract Food related disease or food poisoning is prevalent worldwide and is associated with high mortality. It can be caused by bacteria, viruses, parasites, enterotoxins, mycotoxins, chemicals, histamine poisoning (scombroid) ciguatera and harmful algal bloom (HAB). Illness can also result by red tide while breathing in the aerosolized brevitoxins (i.e. PbTx or Ptychodiscus toxins). Bacterial toxin food poisoning can affect within 1-6 hours and 8-16 hours, and illness can be with or without bloody diarrhea. The common symptoms of food poisoning include abdominal cramps, vomiting and diarrhea. Diagnosis includes examination of leftover food, food preparation environment, food handlers, feces, vomitus, serum and blood. Treatment involves oral rehydration, antiemetic, and anti-peristaltic drugs. Antimicrobial agents may be needed in the treatment of shigellosis, cholera, lifesaving invasive salmonellosis and typhoid fever. Proper care in handling and cooking is important to prevent any food borne diseases. -
Diseases Tiunsmitted by Foods
DISEASES TIUNSMITTED BY FOODS ( A CLASSIFICATION AND SUMMARY) SECOND EDITION U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES PUBLIC HEALTH SERVICE CENTERS FOR DISEASE CONTROL CENTER FOR PROFESSIONAL DEVELOPMENT AND TRAINING ATLANTA. GEORGIA 30333 DISEASES TIUNSMITTED BY FOODS ( A CIJiSSIFICATION AND SUMMARY) SECOND EDITION Frank L. Bryan, Ph.D., M.P.H. — U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES PUBLIC HEALTH SERVICE CENTERS FOR DISEASE CONTROL CENTER FOR PROFESSIONAL DEVE~PMENR AN_QTRAtNING ATLANTA, GEORGIA 30333 1982 DISEASES TRANSMITTED BY FOODS CONTENTS Page 1 INTRODUCTION 2 BACTERIAL DISEASES 2 Diseases of Contemporary Importance 7 Usually Transmitted by Other Means but Sometimes Foodborne Diseases in Which Proof of Transmission by Foods Is Inconclusive Unknown Role in Foodborne Transmission (Pathogenic and 16 Isolated from Foods) 17 VIRAL AND RICKETTSIW DISEASES 17 Epidemiological Evidence of Foodborne Transmission Viral Diseases which Could Possible be Transmitted by Foods but Proof Is Lacking 18 -I.-I PAMSITIC DISEASES LL 22 Always or Usually Transmitted by Foods 29 Usually Transmitted by Other Means but Sometimes Foodborne 33 FUNGAL DISEASES ‘- 33 Mycotoxicoses 37 Mushrooms 42 Mycotic Infections 43 PLANT TOXICANTS AND TOXINS 43 Alkaloids 47 Glycosides 4.9 Toxalbumins Resins 50 50 Other Toxicants, Toxins, and Allergens 54 TOXIC ANIM4LS 54 Fish Shellfish 53 60 Other Marine Animals 62 Non-Marine Animals 64 POISONOUS CHEMICALS 64 Metallic’Containers 65 Intentional Additives 68 Incidental and Accidental Food Additives 75 Allergens -
Pepid Pediatric Emergency Medicine Clinical Topics
PEPID PEDIATRIC EMERGENCY MEDICINE CLINICAL TOPICS NEONATOLOGY • CEPHAL HEMATOMA • CYSTIC FIBROSIS • ABDOMINAL AND CHEST WALL • CEREBRAL PALSY • CYTOMEGALOVIRUS (CMV) DEFECTS (NEONATE AND INFANT) • CHRONIC NEONATAL LUNG • DELAYED TRANSITION • ABNORMAL HEAD SHAPE DISEASE • DRUG EXPOSED INFANT • ABO-INCOMPATIBILITY • COMNGENITAL PARVOVIRUS B 19 • ERYTHROBLASTOSIS FETALIS • ACNE - INFANTILE • CONGENITAL CANDIDIASIS • EXAMINATION OF THE NEWBORN • ALIGILLE SYNDROME • CONGENITAL CATARACTS • EXCHANGE TRANSFUSION • AMBIGUOUS GENITALIA • CONGENITAL CMV • EYE MISALIGNMENT • AMNIOTIC FLUID ASPIRATION • CONGENITAL COXSACKIEVIRUS • FETAL HYDRONEPHROSIS • ANAL ATRESIA • CONGENITAL DYSERYTHROPOIETIC • FETOMATERNAL TRANSFUSION • ANEMIA - SEVERE AT BIRTH ANEMIA • FFEDS/FLUIDS - PRETERM • ANEMIA OF PREMATURITY • CONGENITAL EMPHYSEMA • FPIES(FOOD PROTEIN INDUCED • ANHYDRAMNIOS SEQUENCE • CONGENITAL GLAUCOMA ENTEROCOLITIES SYNDROME) • APGAR SCORE • CONGENITAL GOITER • GASTRO INTESTINAL REFLUX • APNEA OF PREMATURITY • CONGENITAL HEART BLOCK • GROUP B STREPTOCOCCUS • APT TEST • CONGENITAL HEPATIC FIBROSIS • HEMORRHAGIC DISEASE OF THE • ASPHYXIATING THORACIC DYSTRO- • CONGENITAL HEPATITIS B NEWBORN PHY (JEUNE SYNDROME) INFECTION • HEPATIC RUPTURE • ATELECTASIS • CONGENITAL HEPTITIS C • HIV • ATRIAL SEPTAL DEFECTS INFECTION • HYALINE MEMBRANE DISEASE • BARLOW MANEUVER • CONGENITAL HYDROCELE • HYDROCEPHALUS • BECKWITH-WIEDEMANN SYN- • CONGENITAL HYPOMYELINATING • HYDROPS FETALIS DROME • CONGENITAL HYPOTHYROIDISM • HYPOGLYCEMIA OF INFANCY • BENIGN FAMILIAL NEONATAL