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The John Curtin School of Medical Research Annual Review 2012

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The John Curtin School of Medical Research Annual Review 2012 THE JOHN CURTIN SCHOOL OF MEDICAL RESEARCH ANNUAL REVIEW 2012 ANU College of Medicine, Biology & Environment CONTENTS Annual Review 2012 From the Director 3 The John Curtin School of Medical Organisation Chart 4 Research Committees 5 COMMUNITY 7 Official Opening of Stage 3 8 Launch of The John Curtin Medical Research Foundation 9 Professor Gordon Ada 10 Open Day 11 Community Activities 12 RESEARCH IN REVIEW 2012 15 Eccles Institute of Neuroscience 16 Department of Genome Biology 29 Department of Immunology 36 Department of Pathogens and Immunity 45 Department of Molecular Bioscience 47 Department of Translational Medicine 56 Australian Phenomics Facility 60 Biomolecular Resource Facility/Genome Discovery Unit 61 STAFF AND STUDENT ACHIEVEMENTS 63 VISITORS AND COLLABORATIONS 69 STAFF AND STUDENTS 85 Department of Genome Biology 86 Department of Immunology 87 Eccles Institute of Neuroscience 88 Department of Pathogens and Immunity 90 Department of Molecular Bioscience 90 Department of Translational Medicine 92 APF and Animal Services 92 School Services 94 School Administration 95 Students 96 PUBLICATIONS, PRESENTATIONS AND COMMUNITY OUTREACH 99 SUPPORT 129 Grants 130 Financial Overview 134 Donors 135 Sponsors 136 Annual Review 2012 1 2 The John Curtin School of Medical Research FROM THE DIRECTOR Zinkernagel. He will be sadly missed by his many friends and colleagues at the School, who have established the annual Gordon Ada New Investigator Award in his memory. In 2012, we finally completed the long and very necessary redevelopment project that resulted in the new John Curtin School of Medical Research building on the ANU campus. All our staff and students are once again under one roof, carrying out their research in state of the art laboratories and facilities. The Department of Neuroscience expanded and became the Eccles Institute of Neuroscience and we welcomed neuroscientists from the ANU Medical School and Research School of Biology to the building. In August, the 10-year project was finally complete, with local MP Dr Andrew Leigh (Member for Fraser) joining ANU Vice Chancellor Professor Ian Young to declare the third and final stage open in front of current and former staff and students, and supporters of the School. It is my very great pleasure to present the Annual Review from The John Curtin School of Medical Research for In March, Mr Simon McKeon (Australian of the Year 2011) 2012. In this document, we outline the scientific research joined us to launch The John Curtin Medical Research projects underway within the school, and highlight the Foundation at JCSMR. The Foundation was established achievements and successes of our staff and students to raise the public profile of medical research at The throughout the year. In addition, we showcase some of Australian National University, and to source funding the events that we have been involved with at the School, to ensure the continued success of that research. The University and Community level. I hope you will enjoy Foundation Board, led by inaugural Chair Dr Cameron reading the report, and will visit the website jcsmr.anu.edu. Webber, is currently working to support our scientists as au for further details. they carry out studies with the aim of preventing or curing diseases including cancer, diabetes and malaria, and to There were many honours, prizes and awards increase health outcomes nationally and internationally. celebrated at the School in 2012. I would particularly More information about the Foundation and this important like to congratulate Professor Chris Goodnow, who work can be found here: jcmrf.anu.edu.au was awarded The GlaxoSmithKline Award for Research Excellence in September for his pioneering work on In April this year we gathered to farewell JCSMR Director autoimmune, diseases and Professor Greg Stuart, Professor Julio Licinio, as he took up his new position who was elected Fellow of the Australian Academy of as Deputy Director for Translational Medicine and Head, Science for “seminal contributions to understanding how Mind and Brain Theme at the South Australian Health and information is processed by individual nerve cells within Medical Research Institute. As Director from 2009 – 2013, the brain”. Professor Stuart also received a Thomson Julio introduced the discipline of Translational Medicine Reuters Australia Citation Award for the highest cited to the School, and his legacy includes the establishment Neuroscientist in Australia based on research volume and and early success of The John Curtin Medical Research impact over the ten-year period from 2002 to 2011. Foundation. We thank him for his leadership, and wish him well in his future endeavours. In September, we were very saddened to learn of the death of Emeritus Professor Gordon Leslie Ada. Professor Ada was Head of the Department of Microbiology at the Professor Christopher Parish School from 1966-1988, during which time he created and fostered a research environment that led to many Director, The John Curtin School of Medical Research significant immunological discoveries, including the work October 2013 that led to the award of the Nobel Prize in Physiology or Medicine to Professors Peter Doherty and Rolf Annual Review 2012 3 ORGANISATION CHART ANU College of Medicine, Biology and Environment The John Curtin School of Medical Research 2012 Director Professor Julio Licinio Deputy Director Professor Phil Board Departments Genome Immunology Neuroscience Pathogens Translational Translational Biology & Immunity Biosciences Medicine (until September) Molecular Bioscience (from September) Professor Professor Professor Professor Professor Professor David Chris Greg Carola Phil Board Julio Tremethick Goodnow Stuart Vinuesa (until September) Licinio Professor Angela Dulhunty (from September) Administration School Manager Outreach and Education Director’s Offi ce Communications Mr Gerry Lillicrap Dr Madeleine Nicol Dr Anna Cowan Ms Laura Vitler (from February) Services and support ACRF Australian Operations Microscopy & Technical Safety & Biomolecular Phenomics Cytometry Services Training Resource Facility Resource Facility Facility Ms Stephanie Dr Steve Mr Denis Ms Cathy Mr Denis Ms Kate McKenzie Palmer Winslade Coombes Gillespie Coombes (until August) Ms Sonya Glasson (from August) 4 The John Curtin School of Medical Research COMMITTEES Executive Committee Dr Charani Ranasinghe Ms Michelle Townsend Professor Philip Board Mr Dennis Vukoja Dr Anna Cowan Ms Esmee Weil Professor Chris Goodnow Ms Anneloes de Graeff (by invitation) (until May) Safety Committee Dr Rebecca Haddock (until May) Professor Julio Licinio (Chair) Professor Philip Board (Chair) (from August) Mr Gerry Lillicrap (from February) Dr Geeta Chaudhri (Chair) (until August) Dr Madeleine Nicol (until May) Mr Mick Devoy Professor Chris Parish (Co-Chair from July) Dr Renae Domaschenz Professor Greg Stuart Dr Julia Ellyard Professor Carola Vinuesa Dr Sonya Glasson (from August) Mr Danushka Wijesundara (until May) Ms Diane Gooding Mr Gerry Lillicrap (from February) External Relations Committee Ms Kate McKenzie (until July) Dr Peter Milburn Professor Philip Board (Chair) Ms Suzy Pace Dr Anna Cowan Ms Jackie Stenhouse Dr Anselm Enders Dr Krisztina Valter (from September) Ms Anneloes de Graeff Professor Julio Licinio Animal Users Committee Mr Gerry Lillicrap (from February) Dr Madeleine Nicol (Convened December 2012) Professor Chris Parish Dr Anneke Blackburn Professor Thomas Preiss Professor Philip Board Professor Ian Ramshaw Ms Katrina Bowditch (ex officio) Ms Megan Clydesdale (ex officio) Group Leaders Forum Dr Lucy Coupland Professor Angela Dulhunty Professor Ian Ramshaw (Chair) Dr Suzanne Fowler (ex officio) All Group Leaders and Laboratory Leaders belong to the Group Leaders Forum, which meets monthly to discuss matters of importance relating Associate Professor Guna Karupiah to JCSMR Associate Professor Brett Lidbury Professor Klaus Matthaei Education Committee Dr Riccardo Natoli Dr Ian Parish Associate Professor John Bekkers Dr Charani Ranasinghe Dr Anneke Blackburn Dr Charmaine Simeonovic Dr Anna Cowan (Chair) Associate Professor Christian Stricker (Chair) Professor Simon Easteal Miss Preethi Eldi New Revenue Streams Committee Professor Chris Parish Mr Roy Ramiscal Dr Vicki Athanasopoulos Professor Ma-Li Wong Dr Ed Bertram Professor Philip Board Operations Committee Ms Anneloes de Graeff Professor Angela Dulhunty Mr Denis Coombes Professor Simon Easteal Professor Angela Dulhunty (Chair) Dr Julia Ellyard Dr Suzanne Fowler Professor Julio Licinio Ms Cathy Gillespie Mr Gerard Lillicrap Ms Sonya Glasson (from August) Professor Ted Maddess Professor Caryl Hill Dr Madeleine Nicol Dr Gavin Huttley Professor Chris Parish Mr Gerry Lillicrap Mr Geoff Sjollema Ms Kate McKenzie (until July) Professor Greg Stuart Ms Stephanie Palmer Dr Steve Winslade (Chair) Annual Review 2012 5 6 The John Curtin School of Medical Research COMMUNITY Official Opening of Stage 3 Launch of The John Curtin Medical Research Foundation Professor Gordon Ada Open Day Community Activities Annual Review 2012 7 OFFICIAL OPENING – STAGE THREE 1 2 3 4 5 6 On 13 August 2012, Dr Andrew Leigh, Federal Member for Acting Director Professor Chris Parish agreed: “This is a very Fraser declared open the third and final stage of the new JCSMR exciting time for our research school. We are now well equipped building. Dr Leigh paid tribute to all those who had worked so to answer fundamental questions about disease development hard towards the redevelopment project, and wished current
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