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2019 Annual Report

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2019 Annual Report Annual Report 2019 Garvan Institute of Medical Research Annual Report 2019 2019 Strength through collaboration Our vision Our values We see a future where everyone lives a longer, healthier life. Excellence Our mission Innovation We will harness all the information encoded in the genome Collaboration to better diagnose, predict, treat and prevent diseases that have the deepest impact on society. Community Integrity Respect Who we are, what we do The Garvan Institute of Medical Research brings together world-leading clinicians and basic and translational researchers. We are patient focused. Our researchers break down barriers between traditional scientific disciplines to find solutions to disease. Founded in 1963, Garvan’s researchers have made significant advances in genome, epigenome, protein and cell analysis technology. We have revealed causes and developed treatments for diseases including diabetes, osteoporosis, cancer, immune deficiency and autoimmunity. Today, Garvan’s mission builds on those advances, harnessing all the information encoded in our genome, from DNA to complex organ systems, to better diagnose, treat, predict and prevent disease. Garvan’s research has global impact. World-leading people pioneer discoveries across four intersecting research themes. We lead the field in medical genomics, epigenetics, and cellular genomics; cancer; diseases of immunity and inflammation; and diseases of ageing affecting bone, brain and metabolism. Our goal is to translate discovery into meaningful health benefits for those living with disease and their family. Patients, clinical trial cohorts and population cohorts are at the centre of Garvan’s research. We are focused on addressing the unmet needs of those living with disease – where better understanding, new treatments and more effective diagnosis can have the biggest impact. Through cutting-edge technology, facilities, local and international collaborations, Garvan researchers strive, every day, to create a future where everyone lives longer, healthier lives. Garvan’s research is funded through a crucial combination of peer-reviewed government grants and generous philanthropic investment from the community. Garvan is affiliated with St Vincent’s Hospital Sydney and UNSW Sydney. garvan.org.au 1 The organisation As at 31 December 2019 Garvan Institute of Medical Research Board of Directors Executive Leadership Team Chair: Dr John Schubert ao Executive Director: Prof Christopher Goodnow faa frs Deputy Director: Prof Peter Croucher Chief Scientifi c Offi cer: Prof Marie Dziadek Theme Leaders: Prof Susan Clark faa, Prof Peter Croucher, Prof Stuart Tangye, Prof David Thomas Chief Operating Offi cer: Ms Kate Gunn (until December) Acting Chief Operating Offi cer: Ms Samantha Malone and Ms Amanda Brindley (from December) Director of People Culture: Cleo Rowley Director of Garvan Research Foundation: Mara-Jean Tilley Healthy Ageing Cancer Genomics & Epigenetics Immunity & Infl ammation Theme Leader: Theme Leader: Theme Leader: Theme Leader: Prof Peter Croucher Prof David Thomas Prof Susan Clark faa Prof Stuart Tangye Faculty: Faculty: Faculty: Faculty: A/Prof Paul Baldock Dr Christine Chaffer Dr Ozren Bogdanovic Prof Robert Brink Prof Jacqueline Center Dr David Croucher Prof Vanessa Hayes Prof Daniel Christ Prof Tuan Nguyen A/Prof Elgene Lim Dr Timothy Mercer Dr Tatyana Chtanova Prof Mike Rogers Prof Chris Ormandy Prof Seán O’Donoghue A/Prof Elissa Deenick A/Prof Antony Cooper Dr Marina Pajic Dr Robert Weatheritt Prof Christopher Goodnow Prof Trevor Biden A/Prof Joseph Powell Emeritus Fellow: faa frs Prof Jerry Greenfi eld A/Prof Alex Swarbrick Prof John Shine ac faa A/Prof Shane Grey A/Prof Ross Laybutt A/Prof Paul Timpson A/Prof Cecile King Prof Katherine Samaras A/Prof Cindy Ma A/Prof Carsten Schmitz-Peiffer The Kinghorn Cancer A/Prof Tri Phan Prof Herbert Herzog Centre Director: Prof Jonathan Sprent faa frs Prof David Ryugo Prof David Thomas Emeritus Fellow: Emeritus Fellow: Prof Antony Basten ao faa Prof Lesley Campbell am Emeritus Fellow: Prof Don Chisholm ao Emeritus Fellow: Prof John Eisman ao Emeritus Fellow: Prof Ted Kraegen ao Kinghorn Centre for Clinical Genomics Garvan-Weizmann Centre for Cellular Genomics Clinical Head: Mary-Anne Young Head: A/Prof Joseph Powell Scientifi c Head: A/Prof Sarah Kummerfeld Garvan Research Foundation Board of Directors Executive Chair: Mr Russell Scrimshaw Director: Ms Mara-Jean Tilley Deputy Director: Mr Brad Timms The Services Team Chief Operating Offi cer: Ms Kate Gunn (until December) Chief Scientifi c Offi cer: Prof Marie Dziadek Acting Chief Operating Offi cer: Ms Samantha Malone and Grants Administration: Ms Sonja Bates, Ms Grainne Mullen Ms Amanda Brindley (from December) (until May) and Ms Mariette Le Roux (from May) Australian BioResources: Dr Jenny Kingham Human Research Governance: Ms Therese Yim Business Development & Innovation: David Barda Research Ethics and Compliance: Dr Rayson Tan Facilities Business: Amanda Brindley Animal Welfare: Dr Sarah Leonhard Finance & Accounting: Ms Samantha Malone Student Programs: Dr Tracy Anderson Internal Audit & Business Improvement: Ms Carolyn Loughnan Technology Services: Mr Esteve Mayolas Legal Offi ce: Ms Nancy Campisi Building Services: Ms Lynn Croft Building Operations: Mr Ryan Kolster People & Culture Director: Ms Cleo Rowley WHS and Compliance: Ms Abril Rojas-Crisostomo 2 garvan.org.au The organisation As at 31 December 2019 Contents Garvan Institute of Medical Research Board of Directors Executive Leadership Team 4 Garvan Institute Chairman and Executive Chair: Dr John Schubert ao Executive Director: Prof Christopher Goodnow faa frs Director’s Report Deputy Director: Prof Peter Croucher Chief Scientifi c Offi cer: Prof Marie Dziadek 5 Garvan Research Foundation Chairman Theme Leaders: Prof Susan Clark faa, Prof Peter Croucher, Prof Stuart Tangye, and Director’s Report Prof David Thomas Chief Operating Offi cer: Ms Kate Gunn (until December) 6 The year at a glance Acting Chief Operating Offi cer: Ms Samantha Malone and Ms Amanda Brindley (from December) Garvan at a glance Director of People Culture: Cleo Rowley 7 Director of Garvan Research Foundation: Mara-Jean Tilley 8 Collaborations Healthy Ageing Cancer Genomics & Epigenetics Immunity & Infl ammation Publications Theme Leader: Theme Leader: Theme Leader: Theme Leader: 9 Prof Peter Croucher Prof David Thomas Prof Susan Clark faa Prof Stuart Tangye Faculty: Faculty: Faculty: Faculty: 11 Theme Report: Healthy Ageing A/Prof Paul Baldock Dr Christine Chaffer Dr Ozren Bogdanovic Prof Robert Brink Prof Jacqueline Center Dr David Croucher Prof Vanessa Hayes Prof Daniel Christ 15 New hope for Parkinson’s Prof Tuan Nguyen A/Prof Elgene Lim Dr Timothy Mercer Dr Tatyana Chtanova Prof Mike Rogers Prof Chris Ormandy Prof Seán O’Donoghue A/Prof Elissa Deenick 16 Theme Report: Immunity and Inflammation A/Prof Antony Cooper Dr Marina Pajic Dr Robert Weatheritt Prof Christopher Goodnow How medical research changed a young Prof Trevor Biden A/Prof Joseph Powell Emeritus Fellow: faa frs 19 girl’s life Prof Jerry Greenfi eld A/Prof Alex Swarbrick Prof John Shine ac faa A/Prof Shane Grey A/Prof Ross Laybutt A/Prof Paul Timpson A/Prof Cecile King 21 Theme Report: Genomics and Epigenetics 38 Garvan Institute of Medical Research Board Prof Katherine Samaras A/Prof Cindy Ma of Directors A/Prof Carsten Schmitz-Peiffer The Kinghorn Cancer A/Prof Tri Phan 25 White Butterfly spreads its wings Prof Herbert Herzog Centre Director: Prof Jonathan Sprent faa frs 41 Garvan Research Foundation Board of Directors Prof David Ryugo Prof David Thomas Emeritus Fellow: 27 Theme Report: Cancer Emeritus Fellow: Prof Antony Basten ao faa PhD Completions Prof Lesley Campbell am 44 Research Services at Garvan Emeritus Fellow: 30 Prof Don Chisholm ao 45 Post-Doctoral Development Committee Emeritus Fellow: 32 Centre Report: Kinghorn Centre for Prof John Eisman ao Clinical Genomics 46 Leaders in Science and Society seminars Emeritus Fellow: Prof Ted Kraegen ao 34 Centre Report: Garvan-Weizmann Centre for 48 In Memoriam Cellular Genomics Kinghorn Centre for Clinical Genomics Garvan-Weizmann Centre for Cellular Genomics 49 Mr Rick Stevens: Clinical Head: Mary-Anne Young Head: A/Prof Joseph Powell 36 Awards and accolades The future of medical research is in good hands Scientifi c Head: A/Prof Sarah Kummerfeld 50 Partners for the Future Garvan Research Foundation Board of Directors Executive 54 Garvan community Chair: Mr Russell Scrimshaw Director: Ms Mara-Jean Tilley 60 Celebrating pioneering partnerships Deputy Director: Mr Brad Timms The Services Team 63 Scientific publications Chief Operating Offi cer: Ms Kate Gunn (until December) Chief Scientifi c Offi cer: Prof Marie Dziadek 81 Peer-reviewed funding Acting Chief Operating Offi cer: Ms Samantha Malone and Grants Administration: Ms Sonja Bates, Ms Grainne Mullen Ms Amanda Brindley (from December) (until May) and Ms Mariette Le Roux (from May) 87 Join the Garvan family Australian BioResources: Dr Jenny Kingham Human Research Governance: Ms Therese Yim Business Development & Innovation: David Barda Research Ethics and Compliance: Dr Rayson Tan 88 Financial highlights Facilities Business: Amanda Brindley Animal Welfare: Dr Sarah Leonhard Finance & Accounting: Ms Samantha Malone Student Programs: Dr Tracy Anderson We acknowledge the Gadigal and Gundangara peoples, Internal Audit & Business Improvement: Ms Carolyn Loughnan the traditional owners and custodians of the lands on Technology Services: Mr Esteve Mayolas which the Garvan Institute and the ABR are
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