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Report on Schistosomiasis Report Report On TDR/SWG/07 Scientific Working Group Report on Schistosomiasis Report on TDR/World Health Organization Special Programme for Research & Training 20, Avenue Appia in Tropical Diseases (TDR) sponsored by 1211 Geneva 27 Switzerland UNICEF/UNDP/World Bank/WHO Tel: (+41) 22 791-3725 Fax: (+41) 22 791-4854 [email protected] www.who.int/tdr 14–16 November 2005 Geneva, Switzerland The Special Programme for Research and Training in Tropical Diseases (TDR) is a global programme of scientific collaboration established in 1975. Its focus is research into neglected diseases of the poor, with the goal of improving existing approaches and developing new ways to prevent, diagnose, treat and control these diseases. TDR is sponsored by the following organizations: Special Programme for Research & Training www.who.int/tdr in Tropical Diseases (TDR) sponsored by UNICEF/UNDP/World Bank/WHO World Bank TDR/SWG/07 WHO Library Cataloguing-in-Publication Data: Partnerships for malaria control: engaging the formal and informal private sectors: a review / commissioned by the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), in collaboration with the Working Group on Financing and Resources of the Roll Back Malaria Partnership, chaired by The World Bank. “TDR/GEN/06.1”. 1.Malaria - prevention and control. 2.International cooperation. 3.Intersectoral cooperation. I.UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases. II.Global Partnership to Roll Back Malaria. Working Group on Financing and Resources. III.World Health Organization. ISBN 92 4 156334 6 (NLM classification: WC 765) ISBN 978 92 4 156334 5 Copyright © World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases 2006 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: [email protected]). The use of content from this health information product for all non-commercial education, training and information purposes is encouraged, including translation, quotation and reproduction, in any medium, but the content must not be changed and full acknowledgement of the source must be clearly stated. A copy of any resulting product with such content should be sent to TDR, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland. TDR is a World Health Organization (WHO) executed UNICEF/UNDP/World Bank/World Health Organization Special Programme for Research and Training in Tropical Diseases. The use of any information or content whatsoever from it for publicity or advertising, or for any commercial or income- generating purpose, is strictly prohibited. No elements of this information product, in part or in whole, may be used to promote any specific individual, entity or product, in any manner whatsoever. The designations employed and the presentation of material in this health information product, including maps and other illustrative materials, do not imply the expression of any opinion whatsoever on the part of WHO, including TDR, the authors or any parties cooperating in the production, concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delineation of frontiers and borders. Mention or depiction of any specific product or commercial enterprise does not imply endorsement or recommendation by WHO, including TDR, the authors or any parties cooperating in the production, in preference to others of a similar nature not mentioned or depicted. The views expressed in this health information product are those of the authors and do not necessarily reflect those of WHO, including TDR. WHO, including TDR, and the authors of this health information product make no warranties or representations regarding the content, presentation, appearance, completeness or accuracy in any medium and shall not be held liable for any damages whatsoever as a result of its use or application. WHO, including TDR, reserves the right to make updates and changes without notice and accepts no liability for any errors or omissions in this regard. Any alteration to the original content brought about by display or access through different media is not the responsibility of WHO, including TDR, or the authors. WHO, including TDR, and the authors accept no responsibility whatsoever for any inaccurate advice or information that is provided by sources reached via linkages or references to this health information product. Printed in Italy Design: Thierry Cailler All photos are from the TDR Photo library: WHO/TDR/Craggs, Crump, Edwards, Pagnoni, Reile, Stammers and Taylor-Robinson. Report of the Scientific Working Group meeting on Schistosomiasis Geneva, 14–16 November, 2005 TDR/SWG/07 Original: English Copyright © World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases, 2006 All rights reserved. The use of content from this health information product for all non-commercial education, training and information purposes is encouraged, including translation, quotation and reproduction, in any medium, but the content must not be changed and full acknowledgement of the source must be clearly stated. A copy of any resulting product with such content should be sent to TDR, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland. TDR is a World Health Organization (WHO) executed UNICEF/UNDP/ World Bank/WHO Special Programme for Research and Training in Tropical Diseases. This information product is not for sale. The use of any information or content whatsoever from it for publicity or advertising, or for any commercial or income-generating purpose, is strictly prohibited. No elements of this information product, in part or in whole, may be used to promote any specific individual, entity or product, in any manner whatsoever. The designations employed and the presentation of material in this health information product, including maps and other illustra- tive materials, do not imply the expression of any opinion whatsoever on the part of WHO, including TDR, the authors or any parties cooperating in the production, concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delineation of frontiers and borders. Mention or depiction of any specific product or commercial enterprise does not imply endorsement or recommendation by WHO, including TDR, the authors or any parties cooperating in the production, in preference to others of a similar nature not mentioned or depicted. The views expressed in this health information product are those of the authors and do not necessarily reflect those of WHO, includ- ing TDR. WHO, including TDR, and the authors of this health information product make no warranties or representations regarding the content, presentation, appearance, completeness or accuracy in any medium and shall not be held liable for any damages whatsoever as a result of its use or application. WHO, including TDR, reserves the right to make updates and changes without notice and accepts no liability for any errors or omissions in this regard. Any alteration to the original content brought about by display or access through different media is not the responsibility of WHO, including TDR, or the authors. WHO, including TDR, and the authors accept no responsibility whatsoever for any inaccurate advice or information that is provided by sources reached via linkages or references to this health information product. Design: Lisa Schwarb Layout by Inís: www.inis.ie Contents Executive summary . 1 Background and rationale . 2 Objectives and overview . 4 Priorities . 12 Annex 1 AGENDA: Scientific Working Group on Schistosomiasis . 17 Annex 2 LIST OF PARTICIPANTS: Scientific Working Group on Schistosomiasis . 21 Annex 3 WORKING PAPERS: Scientific Working Group on Schistosomiasis . 27 WORKING PAPER 1. Research needs of the national schistosomiasis control programme in China . 28 WORKING PAPER 2. Current situation and research needs for schistosomiasis control in Egypt . 35 WORKING PAPER 3. Implementation strategies for schistosomiasis control in Uganda, and research needs under the programme . 38 WORKING PAPER 4. Quantification of disease burden due to schistosomiasis . 46 WORKING PAPER 5. Schistosomiasis in women of childbearing age, including in pregnancy . 53 WORKING PAPER 6. Measuring schistosomiasis morbidity . 57 WORKING PAPER 7. Clinical schistosomiasis . 62 WORKING PAPER 8. Progress towards the detection of schistosomiasis . 67 WORKING PAPER 9. Research towards new treatments for schistosomiasis . 72 Schistosomiasis WORKING PAPER 10. The sociocultural context of schistosomiasis control: current knowledge and future research needs . 76 WORKING PAPER 11. The social determinants of schistosomiasis . 84 WORKING PAPER 12. Ecological and other factors related to schistosomiasis . 91 WORKING PAPER 13. Research on the molluscan intermediate hosts for schistosomiasis: what are the priorities? . 95 WORKING PAPER 14. Schistosomiasis and immunity . 105 WORKING PAPER 15. Genomics and proteomics: towards new targets in schistosome research . 109 Report of the
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