Open Letter to All APS Members EDITORIAL from Franklvn G. Knox, President Lend a Helping Hand d Dear APS Member: increased. The Council shall consist of six The recent gathering of physiologists in The Council of The American Physio- Council members plus the President, Pres- Vancouver for the XXX International Con- logical Society met on Friday, August 22, ident-elect, and Past President. Two nea gress of Physiological Sciences demon- 1986, to consider a proposal for restructur- Council members shall be elected each strated once again that an essential ele- ing the governance of the Society. The year for a three-vear term. ment in the continued vitality of science is recommendation for governance that For the purposes of governance, a clear interaction at the international level. Phvs- emerged from that meeting was approved identification of the makeup of Sections iologists from industrialized democracies, bv Council for consideration by the mem- becomes necessarv. The proposal recom- developing countries, and Communist bership of the Society. We solicit your re- mends that a Section consist of any group countries gathered enthusiastically for di- action to the proposal by open discussion of 100 regular members of the Society who rect and fruitful exchange among col- at the business meeting of the Society to express a primary affiliation and whose leagues. Whether in one-on-one situations be held in New Orleans October 8, 1986, statement of organization and procedures or large lecture halls, physiological under- and by mail if you are unable to attend the have been approved bv Council. Each Sec- standing was enhanced and each partici- meeting. Following the Fall meeting of the tion shall elect one of its members to serve pant gained new insights. Society, Council will consider all of the on the Section Advisory Committee for a For scientists from the United States and input from the membership and finalize a term of three years. The Section Advisory other industrialized democracies, the op- proposal for publication in The Physiologist Committee shall elect a chairperson from portunities for exchange at national and/ and subsequent action at the Spring meet- the Committee to serve for a three-year or international meetings are numerous. ing of the Society in Washington in 1987 term. The chairperson of the Section Ad- Fortunately, the research support structure (the Centennial celebration). visory Committee shall be an ex-officio in countries like the United States facili- The proposal represents the input from member of the Council. tates and encourages scientists to share the Long-Range Planning Committee, the To accomplish a balanced representa- ideas at scientific meetings. The concept Section Advisory Committee, and the tion over time for the various Sections of of scientific exchange remains despite the Council. The basic goal of the restructuring the Society, a Nominating Committee is current period of fiscal conservatism asso- of the governance of the Society is to in- recommended by the governance pro- ciated with Gramm-Rudman-Hollings. crease the representation by the Sections posal. The Nominating Committee shall Scientists from developing countries of the Society. As a natural outgrowth of consist of the immediate Past President, also have ample opportunities for ex- the explosion of physiologic knowledge, who will serve as chairman, and six mem- change. However, the lack of “hard cur- specialization of interests has occurred. bers elected from the Section Advisorv rency” makes it difficult, if not impossible, The recognition of this specialization Committee. The elected members will to participate. The limited resources avail- through the creation of Sections and sec- serve for two-year terms, with three being’ able to scientists in developing countries tionalization of the journals allows for elected each year. The chairpersons of the make it necessary for them to be extremely communication among those with special- Program Executive Committee and the selective when identifying a meeting to ized interests and yet, at the same time, Publications Committee shall be ex-officio attend. As a result, international congresses the umbrella of the Society as a whole members without vote. The Nominating and their associated satellite symposia are recognizes the integrative function of our Committee shall solicit candidates from often the meeting of choice for investiga- discipline. The new governance structure the Society membership bv mail, and shall tors from developing countries. recognizes the importance of having sec- select a slate of candidates from those During the Vancouver meeting, I had tional input to the governance of the So- nominated by the Society membership. the opportunity to talk with Renato Alber- ciety as a whole. The slate presented by the Nominating tini, President of the Latin American Asso- To accomplish these ends, the proposal Committee shall be such that no more than (Continued on p. 190) recommends that the size of Council be ( Continued on p. 198) EDITORIAL plimentary or subsidized copies of the CONTENTS (Continued from p. 189) journals and books can be provided. Professional associations can also help EDITORIAL ciation of Physiological Sciences (ALACF), about the opportuni:,zs for research in identify foundations and other philan- Lend a Helping Hand thropic agencies willing to support pro- M. Frank 189 Latin America. According to Dr. Albertini, grams for developing countries under the LE’ITER TO MEMBERS countries in Latin America often have a corps of highly qualified scientists in spe- auspices of the association. Open Letter to All APS Members For APS, our interactions with physiol- F. G. Knox 189 cific areas of physiology. For the ALACF countries the areas of excellence include ogists in developing countries have previ- OFFICE OF NAVAL RESEARCH hypertension, neurophysiology, and repro- ously been through their national physio- Management of the Physiology ductive physiology. Despite strength in logical societies. Within the Americas, Program of the Office of Naval these areas, progress is slow because of these interactions have resulted in the par- Research ticipation of Latin American physiologists F. G. Hempel 191 the lack of adequate research equipment, chemicals, and scientific journals. in several of our meetings, including the PUBLIC AFFAIRS The enhancement of research in devel- forthcoming 1987 San Diego meeting in Federal Appeals Court Rules on oping countries has often been a result of which the ALACF will be a conjoining so- Question of Standing 192 scientist exchanges, sabbatical opportuni- ciety. The hand of friendship is also being Resolution Honoring American ties, and postdoctoral training. Unfortu- extended through the pending bylaw Physiologists Introduced in nately, these opportunities depend on re- change that will make physiologists in “all Congress by Rep. Walgren the Americas” Regular members of APS, a W. M. Samuels 192 sources available from granting agencies in developing countries. In the United change that has been warmly received by APS NEWS States, many of these programs have been physiologists in South America. Centennial Update 194 early victims of the budget knife. For phys- However, these activities are minor con- News from Senior Physiologists 195 iology to prosper in developing countries, tributions to the development of self-suf- Federation Proceedings: New individual physiologists and professional ficiency in Third world countries. The APS Editorial Policy 195 scientific organizations must become more and other associations should serve as Cardiovascular Section Report 195 actively involved. “matchmakers,” coordinating activities be- Section Advisory Committee Report 196 Most of us have had opportunities to tween scientists and identifying resources Hymen Samuel Mayerson (1900- meet scientists from developing countries to facilitate the exchange of information, 1985) 197 and discuss their problems. In the future, equipment, or personnel. Perhaps the role Restoration of Stephen Hales’ let these discussions be the start of scien- of APS should be to assist strong depart- Grave, Teddington, London 198 tist-to-scientist cooperation in which a col- ments of physiology to “adopt a depart- Ohio State Science Fair 199 league is provided with a textbook or jour- ment” in a developing country. Such activ- ities can only serve to advance science, IUPS NEWS nal. To enhance self-sufficiency it is im- portant for developed countries to initiate increase awareness, and contribute to in- General Assembly 199 ternational amity. Finnish Physiological Society to staff exchange programs, visiting lecture- ships, equipment and textbook donations, It is important to remember that one Host XXX1 International individual can play a significant role in Congress 199 and financial assistance. Even the provi- sion of three-month-old copies of Current helping a Third world country achieve ANNOUNCEMENTS 200 Contents can open up a whole new world self-sufficiency. Four years ago, through OPINION of scientific discovery. the College of Agriculture at Michigan To the Editor. S. R. Cohen 201 Professional organizations such as APS State University, Harvey Sparks, Jr., APS President-Elect, became aware of the Uni- PEOPLE AND PLACES 201 can provide some of the impetus for en- hancing the research ability of scientists in versity of Zimbabwe’s desire to expand BOOKS RECEIVED 201 developing countries. Occasionally, com- their exchange program into the biomedi- cal sciences. Through his initiative, stu- Publications Committee: Chairman, P. C.Johnson; dents from Zimbabwe began arriving in The Physiologist Members, John S. Cook, William F. Ganong, Leonard East Lansing and physiology faculty visited Published bimonthly and R. Johnson, and Jean McE. Marshall. Publications the University of Zimbabwe. As part of his distributed bv Manager and Executive Editor, Stephen R. Geiger; forthcoming sabbatical, Dr. Sparks will be Production Manager, Brenda B. Rauner; Editorial The American Physiological Society St@ Laura North and Lorraine Tucker. working in Zimbabwe to help strengthen 9650 Rockville Pike Subscriptions: Distributed to members as part of their physiology programs and develop in- Bethesda, Maryland 20814 their membership; nonmembers and institutions, dependent investigators. $60.00per yearin the United States;elsewhere $75.00. In the future, The Physiologistwill carry ISSN 0031-9376 Single copies and back issues,including Fall Abstracts issue,when available, $15.00 each. In 1986 subscrib- more information about physiological re- ers to The Physiologist will receive it, the abstractsof search and teaching in developing coun- Martin Frank, Editor the Fall Meeting of the American Physiological Soci- tries. If you have ideas or are willing to and ety,and News in Physiological Sciences. The American “lend a helping hand,” please let us know. Executive Secretary-Treasurer Physiological Society assumes no responsibility for the statementsand opinions advancedby contributors Franklyn G. Knox, President to The Physiologist. Martin Frank Deadline for submission of material for publica- Howard E. Morgan, Past President tion: Dec. 5, February issue;Feb. 5, April issue;April Harvey V. Sparks, Jr., President-Elect 5, June issue;June 5, August issue, Aug. 5, October Shu Chien, JayA. Nadel, Norman C. issue; Oct. 5, December issue. If you change your Staub, and Aubrey E. Taylor, Councillors address or telephone number, please notify the central office as soon as possible.

190 THE PHYSIOLOGIST Management of the Physiology Program of the Office of Naval Research

Franklin G. Hempel

Research and Laboratorv J Management.u I OfficeJd ofJ Naval Research

The origin of the Office of Naval Re- Business Daily, which define agency pro- reached on whether submission of a full search can be traced to the final months of grams and restate the principle that unso- proposal is to be encouraged. If affirma- World War II and the phaseout of the Of- licited basic research proposals function as tive, guidelines for the preparation of the fice of Scientific Research and Develop- competitively solicited for the purposes of formal proposal are sent to the investiga- ment (OSRD), which had coordinated sci- legally awarding contracts. tor. The formal proposal, when received, ence research for the federal government. Since the beginning of the ONR, physi- is reviewed again by those same Scientific The navy responded to the OSRD termi- ological research has been a major pro- Officers and ad hoc reviewers, if needed. nation by creating in May 1945 an Office gram area because the health and perform- Frequently, the scientific merit of the pro- of Research and Inventions (ORI) to over- ance of military personnel have tradition- posal is readily apparent and the funding see all research, experimental, test, and ally been challenged by unusual opera- documents can be prepared. Other cases developmental activities underway for the tional or environmental conditions. Con- require additional opinions, solicited by U.S. Navy. The wartime Office of Patents sequently the Physiology Program was di- mail, either directly from the Scientific Of- and Inventions and the navy’s Office of rected largely toward operational and ficer or through contractual arrangements Research and Development were soon stress physiology, especially during the with organizations such as the Federation combined with the ORI, which now be- first decade, 1946-1956. At that time, phys- of American Societies for Experimental Bi- came the focal group for planning a newer iologists addressed the practical and ap- ology or the American Institute of Biolog- organization that would, in time, supervise plied problems of heat stress,cold, anoxia, ical Sciences. The reports from the outside navy research and development as well as battle fatigue, thermal injury, exposure to reviewers are considered advisory rather contract for science projects in nonmilitary radar, sleep deprivation, extreme exertion, then decisive, and no priority scores are institutions. The OR1 did not have the au- and head injury. The goals were, to a great assigned. Reviewers’ comments are sel- thority, however, to issue contracts. Mean- extent, to define the limits of human tol- dom sent to applicants, and any questions while, Congress passed legislation that cre- erance to these battlefield conditions. Re- raised about funding decisions or scientific ated an Office of Naval Research (ONR) cently hyperbaric physiology was a signif- merit are usually communicated by tele- “to plan, foster and encourage scientific icant part of this program, responding to phone. The final determinants for any pro- research in recognition of its paramount requirements of navy divers and submarin- posal are, as always, availability of funds, importance as related to the maintenance ers. Along with this were traditional phys- the scientific merit, and the programmatic of future naval power and the preservation iology projects in areas as diverse as ther- relevance of the research project. After the of national security.” In August 1946 the moregulation, biodynamics, and magne- concurrence is obtained from the Division OR1 became the ONR, and thus was toencephalography. However, trends have Head, Associate Director of Research, and formed the first federal agency with a mis- moved toward the neurosciences, and Director of Research, a research contract is sion to support basic research in universi- greater emphasis has been placed on the negotiated. ties and other nonprofit organizations. molecular level of biological activity. Sys- Funding awardsfrom the ONR are made Within six years, the Atomic Energy Com- tems and organ levels of research are no as contracts for basic research or as grants mission, the National Institutes of Health, longer as actively sponsored in the ONR for symposia and foreign institutions. In the National Science Foundation, and the Physiology Program. Today, scientists are general usage “contract” implies the ac- sister military agencies, the Army Research asked to use techniques of molecular bi- quisition of property or services for the Office and the Air Force Office of Scientific ology to understand the physiological and direct benefit of the federal government, Research, followed. Each of these agencies biochemical mechanisms involved in neu- and the contract requires substantial fed- adopted what was then an unorthodox ap- rotransmission, neuromodulation, neural eral involvement during performance of proach to funding research, i.e., by award- plasticity, and cell-to-cell communication. the contemplated activity. In practice, ing contracts that would take into account The review procedures leading to fund- however, the research grants written by the unpredictable outcomes inherent in ing of contracts by the ONR are essentially other funding agencies and the contracts basic research and would allow the re- the same for all of the science and engi- written by ONR for research function in search investigator the flexibility needed neering directorates. In the Physiology similar ways, and it appears, in fact, that for submitting ideas through an unsolicited Program, a research contract is usually ini- most agencies developed a grant format proposal. tiated by contact directly with a Scientific modeled after contract provisions and The ONR reached its 40th anniversary Officer. If, after discussion of the proposed clauses. in August 1986; this fundamental method research, a fit is found with program goals, The question may be raised whether the of awarding contracts continues, with mod- the investigator is asked to submit a pre- selection procedures for contracts, without est changes, to function successfully. The liminary proposal of two to three pages, the use of study sections or open discus- most recent federal legislation pertinent to wherein the research objectives and hy- sion by assembled experts and without this is the Competition in Contracting Act potheses involved are outlined. A curricu- assignment of priority scores, can be effec- of 1984. In accordance with this Act, the lum vitae is often included. These prepro- tive and unbiased. In reply, the experience service agencies have published “Broad posals are read usually by three or more AgencyAnnouncements” in the Commerce Scientific Officers, and a decision is (Continued on p. 198)

Vol. 29, No. 5, 1986 191 the thoroughfare, generating both public PUBLIC AFFAIRS and media attention to the issue of the monkevs. The activists also initiated a national let- ter-writing campaign to the Congress. Leg- Federal Appeals Court Rules on islators reported that they were receiving Question of Standing more than 300 letters demanding the re- lease of the monkeys from constituents for A federal court of appeals has ruled that The defendants in the case, the Institute every letter they received from the scien- animal rights supporters and organizations for Behavioral Research and NIH, were tific and education communities. do not have the right to file civil suits on joined in the appeal by 69 scientific soci- behalf of animals. eties and educational associations, which Resolution Honoring A three-judge panel at the US Court of filed jointly an amicus curiae brief. American Physiologists Appeals in Richmond, VA, upheld a federal Included in the 69 organizations were district court ruling that neither animal APS, which was a member of the steering Introduced in Congress rights groups nor individuals have been committee, the Association of Chairmen of by Rep. Walgren granted standing by the courts. Without Departments of Physiology, and FASEB. standing an organization or an individual The other members of the steering com- A resolution has been introduced in the cannot initiate a civil suit. mittee in addition to APS were the Ameri- Congress calling upon President Ronald However, the S-year quest for standing can Psychological Association, the Associ- Reagan to issue a proclamation honoring by animal rights advocates is expected to ation of American Medical Colleges, the American physiologists. be continued by an appeal to the US Su- National Association for Biomedical Re- The resolution was introduced by Rep. preme Court. search, the National Association of State Doug Walgren of Pittsburgh in recognition The issue began in September 1981 Colleges and Land Grant Universities, of the American Physiological Society’s when county police confiscated 17 mon- Pharmaceutical Manufacturers Association, 1987 Centennial Year and the Founders keys from a Silver Spring, MD, research and the Society for Neuroscience. Week scientific program in Washington, facility after having charged a research sci- While the scientific and educational DC, March 2%April 3, 1987. entist with animal cruelty. Animal rights communities were providing support for Enactment of H. J. Res. 677, “American advocates filed in federal district court a the defendants, two congressional sup- Physiologists Week,” requires that a major- civil suit seeking custody of the monkeys, porters of the animal rights movement ity of the members of both houses join as which were being maintained by the Na- pushed for legislative support for the plain- cosponsors of the resolution. Thus, all APS tional Institutes of Health (NIH) under an tiffs. members and their colleagues should con- order from a Maryland court. Rep. Charlie Rose (D-NC) proposed an tact their state’s delegation and request that A federal magistrate reviewing the suit amendment to the Animal Welfare Act (HR each member of the delegation cosponsor recommended that it be dismissed because 4535) that would give standing to any per- H. J. Res. 677, which has been referred to the courts had not granted standing to an- son wanting to file a civil suit against the the Committee on Post Office and Civil imal rights advocates. The magistrate’s rec- federal government on his own behalf or Service. ommendation was upheld by the federal on behalf of any animal if it is believed The need to request Congressional rep- district court judge. that a federal agency has failed to enforce resentatives at this time to cosponsor the Standing, in general terms, is the rec- fully the provisions of the act regarding the resolution is vital, as enactment must be ognition granted by a court to private citi- care and treatment of animals. accomplished during this session of the zens and organizations as plaintiffs with The enactment of this bill would effec- 99th Congress, which is expected to ad- legally protectable and tangible interests tively bypass the judgment of the court and journ before December. at stake in litigation. would open the doors to civil actions In introducing the resolution Walgren The plaintiffs-International Primate against any federal agency that is believed told his colleagues: Protection League, Animal Law Enforce- to have failed to enforce the standards of “I introduce today a joint resolution to ment Association, People for the Ethical care for animals used by universities, re- designate the week beginning March Treatment of Animals, and six individ- search facilities, or other institutions cov- 29,1987, as “American Physiologists Week” uals-appealed the decision on the ered by the act. to make the 100th anniversary of the found- grounds that they were entitled to standing Rep. Robert C. Smith (R-NH) and Sen. ing of the American Physiological Society. because a bonding relationship with the Alan Cranston (D-CA) introduced congres- This Society and the work of physiologists monkeys had been established as a result sional resolutions calling for NIH to re- have contributed immensely to the cure, of the plaintiffs weekly visit with monkeys, lease the monkeys to PETA. The resolu- treatment, and understanding of many dis- providing them with fresh fruit, toys, and tions were introduced after more than 155 eases. a television set. representatives and 55 senators signed a “Just two of the areas in which physiol- The granting of standing to animal rights letter to the director of NIH requesting ogy plays a crucial role are the fields of supporters and organizations is a signifi- that the monkeys be released. PETA pro- biomedical and behavioral research. Along cant issue, inasmuch as it is a legal recog- posed to place the monkeys in a refuge with many other fields of study, the ad- nition that animal rights advocates have a near San Antonio, TX. vances that have come in these two areas guardian relationship with laboratory ani- The congressional pressure on NIH was of medical care have resulted directly from mals. One of the consequences could be heightened by an around-the-clock vigil on the study of physiology and continue to be in terms of the number of suits that could the NIH campus that was started in late fields of incredible potential for dramatic be filed against individuals and institutions April. Animal rights demonstrators erected breakthroughs that would improve the for alleged animal abuse in educational a tent along the highway fronting the cam- health of humankind. and research programs. pus and placed billboards on both sides of (Continued on p. 198)

192 THE PHYSIOLOGIST 99TH CONGRESS 2~ SESSION H.J. RES.677

To designate the week beginning March 29, 1987, as “American Physiologists Week”.

IN THIG HOUSE OF REPRESENTATIVES

JULY 17, 1986 Mr. WALGREN introduced the following joint resolution; which was referred to the Committee on Post Office and Civil Service

To designate the week beginning March 29, 198’7, as “American Physiologists Week”.

Whereas 1987 marks the one-hundredth anniversary of the founding of the American Physiological Society; Whereas physiology is the taproot for all of the life sciences; Whereas early findings by physiologists resulted in the develop- ment of blood transfusions and modem anesthesia, eradica- tion of many diseases, and the discovery of antibiotics; Whereas physiology continues to be the fountainhead from which life science research enriches the health and longevity of humans and animals; Whereas internationally renowned physiologists from every con- tinent are coming to the District of Columbia to engage in scientific and educational dialogue with the American Physi- ological Society during its Centennial Week celebration of a century of progress in physiology: Now, therefore, be it

1 Resolved by the Senate and House of Representatives

2 of the United States of America in Congress assembled, 3 That the week beginning March 29, 1987, is designated as 4 “American Physiologists Week”. The President is requested 5 to issue a proclamation calling on the people of the United 6 States to observe such week with appropriate ceremonies and 7 activities.

Vol. 29, No. 5, 1986 193 ture and reception for APS and FASEB week, special events will be available for APS NEWS members at the Washington Hilton. On participants, including an evening at the Wednesday morning, April 1, APS will have Kennedy Center for the Performing Arts a plenary session during which Dr. Karl and tours of Washington landmarks. Centennial Update Ullrich, a distinguished physiologist, will We look forward to your participation in present the Physiology in Perspective, Wal- this very special meeting in which past and Many threads that form the fabric of the ter B. Cannon Lecture. The plenary lecture present will be woven into the fabric that APS Centennial Celebration in Washing will be followed by the APS business meet- constitutes experimental biology. ton, DC, March 29-April 3, 1987, are com- ing. The USNC/IUPS is sponsoring a spe- Plenary lectures and topic categories for ing together. The week-long celebration cial lecture and closing reception at the contributed papers with chairperson and of “A Century of Progress in Physiology” National Academy of Sciences for APS society responsible for theme component will be addressed through a series of sym- members on Thursday, April 2. During the are shown below. posia, special lectures, and penetrating re- views designed to examine the growth of Plenary Lectures Contributed Paper Topic Categories ideas and development of new techniques. To help in the celebration, distinguished David Baltimore (Whitehead Institute of Development Regulation of Mammalian physiologists from North America and Biomedical Research), Developmental Genes (A. Ault, American Association of abroad have been invited to participate in Regulation of Mammalian Genes, 11:30 Immunologists), 8:30 A.M., March 30,1987. the symposia program. A.M., March 30,1987. The intersociety program of the 1987 Floyd E. Bloom (Scripps Clinic and Re- Neurotransmitters (Anthony Angel, Amer- FASEB Meeting will be directed to a single search Institute), Neurotransmitters: Past, ican Physiological Society), 1:45 P.M., theme, “A Century of Progress.” This Present, and Future, 1230 P.M., March 30, March 30, 1987. theme was chosen to highlight the prog 1987. ress achieved in the last century by exam- ination of the present leading edges and Hector F. DeLuca (University of Wiscon- Vitamin D (Connie M. Weaver and Robert growth points in fields representative of sin-Madison), The Vitamin D Story: A Suc- P. Heaney, American Institute of Nutri- the FASEB membership. To support this cess of Basic Science in the Treatment of tion), 830 A.M., March 31, 1987. objective, a novel and exciting format has Disease, 1130 A.M., March 31,1987. been developed for presentation of the Roger Guillemin (Salk Institute for Biolog- Endocrine Regulation (Howard E. Morgan, thematic program. The program will in- ical Studies), Endocrine Regulation: The American Physiological Society), 1:45 P.M., clude two related components. First, dis- Case of the Control of Pituitary Functions, March 31, 1987. tinguished investigators acknowledged as 12:30 P.M., March 31, 1987. leaders in their fields, nominated by the FASEB member societies, will present Philip Leder (Harvard University), Mis- Oncogene Expression (Harold E. Varmus, their perceptions of critical problems in a placing Oncogenes: Studies Using Trans- American Association of Pathologists), series of plenary lectures. Second, the top genie Mice, 1230 P.M., April 1, 1987. 1:45 P.M., April 1, 1987. its addressed in the plenary lectures have Solomon H. Snyder (Johns Hopkins Uni- Neural Receptors (Horace Loh, American been used to define a series of special versity), Neural Receptors, 11:30 A.M., Society for Pharmacology and Experimen- topic categories for the solicitation of ab- April 2, 1987. tal Therapeutics), 8:30 A.M., April 2, 1987. stracts,and the papers contributed in these topic categories will be arranged into Sir John Vane (St. Bartholomew’s Hospital Inflammation and the Mechanism of Ac- minisymposia and poster sessions that fur- Medical College), Inflammation and the tion of Anti-inflammatory Drugs (Peter A. ther explore the areas defined in the plen- Mechanism of Action of Anti-inflammatory Ward, American Association of Patholo- ary lectures. Drugs, 12:30 P.M., April 2, 1987. gists), 1:45 P.M., April 2, 1987. In addition to the scientific meeting, the proceedings will include an opening lec- THE FASRB ‘87 ABSTRACT RECEIPT DEADLINE IS NOVEMBER 19,1986

194 THE PHYSIOLOGIST News From Senior Section Report Physiologists Cardiovascular Letter to E. B. Brown: The Cardiovascular Section sponsored Section, which is open to any APS member, Adolph Surtshin is in private medical four symposia at the 1985 Fall Meeting in the Cardiovascular Section elects Fellows. practice, a member of the Voluntary Fac- Niagara Falls, NY: Theme Symposium I: The total number is not to exceed 5% of ulty of the California College of Medicine, Neuro Humoral Regulation of Water and the total number of regular Section mem- University of California at Irvine. Though Electrolyte Balance Session I-Neuropep bers. Nominations for new Fellows are of. he no longer engages in scientific research tides: Angiotensin and Vasopressin; Theme fered by existing Fellows; these nomina- or writing, his background in physiology Symposium I: Neuro Humoral Regulation tions are voted on by the Steering Com- has been serving as a basis for his teaching of Water and Electrolyte Balance Session mittee. Fellows must be regular members activities with resident physicians at the II-Neural and Humoral Control of Kid- of the APS and must have published meri- Northridge Hospital Medical Center in ney Functions; Theme Symposium I: torius research in cardiovascular physiol- Northridge, California since 1976. Neuro Humoral Regulation of Water and ogy. In 1986, the following members were Electrolyte Balance Session Ill-Neural elected to Fellowship: Roger A. Norman, Letter to Arthur Otis: Humoral Regulation of Electrolytes and Jr., Frank Chi-Pong Yin, Nick Tripodo, Wil- William J. Whalen is still involved in Water Balance at the Microcirculation; and liam S. Spiellman, R. Davis Manning, Mar- research, primarily as a consultant with Dr. Theme Symposium I: Neuro Humoral Reg tin Lew Winter, Raymond Koehler, and Nair at Louisiana Tech on the mechanism ulation of Water and Electrolyte Balance Eric Hoffman. of chemoreception in the cat carotid body. Session IV-Neural Humoral Mechanisms The following symposia were spon- Since retiring in 1980 from Case-Western of Thirst and Salt Appetite. sored or cosponsored by the Cardiovascu- Reserve he has ‘had a ball” golfing (and The annual dinner and business meet- lar Section of the APS at the 1986 Annual making golf bags), precious-metal plating, ing of the Cardiovascular Section was held FASEB Meetings: Myosin Polymorphism in playing bridge, gardening, fishing, and on Tuesday, April 15,1986, at the Missouri Striated Muscle I and II-cosponsored politicking for liberal candidates. He Athletic Club. Two hundred fifty members with the Muscle Group, Cell and General writes: ‘I miss seeing old friends at meet- attended the dinner. The annual Carl Wig Physiology; Chair: M. Kushmerick, S. ings but good memories of them remain.” gers award was presented to Dr. Kiichi Wiengrad, R. L. Moss; Control of Coronary Sagawa, Department of Biomedical Engi- Circulation and Myocardial Function; neering, Johns Hopkins University, Balti- Chair: G. Kaley; Vasomotor Control- Letter to Roy Greep: more, MD. Dr. Sagawa presented an after- Functional Hyperemia and Beyond; Chair: Lorrin A. Riggs, retired officially from dinner lecture entitled: “Observing Car. B. Duling; Granulocytes and Oxidative ln- Brown University in 1977, writes that he is disc Contraction Through the Pressure- jury in Myocardial lschemia and Reperfu- now “happily cutting back.” He is down to Volume Window.” sion Injury; Chair: R. L. Engler and 8. R. one graduate student, a small space in the The annual Lamport Award was pre- Lucchesi; and Update in Cardiovascular lab, and no more grant applications, He sented to Dr. Ann Baldwin, Department of Neurobiology: The Neurobiology of Arte- notes that several APS members, among Physiology, The University of Arizona rial and Cardiac Baroreceptor Afferents- them Lloyd Beidler, Hal Davis, Dan Ken- Health Sciences Center, College of Medi- cosponsored with APS Nervous System; shalo, Carl Pfaffman, and himself, have cine, Tucson, AZ on April 15,1986, at the Chair: C. M. Ferrario and V. Bishop. written autobiographical chapters on their banquet. Dr. Baldwin received a certificate Three new members were elected to the specialty for Founders of Sensory Science, of award and a check for $280.08 from the Nominating Committee: Hermes Kontos, edited by APS member Bill Dawson and Cardiovascular Section. Carl Rothe, and James Covell. by Jay Enoch and published by Springer-’ Eight new members were elected to Verlag in 1984. Fellowship in the Cardiovascular Section. In addition to regular membership in this Loring B. Rowell, Chairman Federation Proceedings: New Editorial Policy

In 1987, Federufion Proceedingswill in- stitute a policy of publishing two new types of article: I) Brief, definitive, and essentially final research communications of unusually broad interest that are considered to war- rant prompt publication; and 2) State-of-the-art reviews, drawn, as far as possible, from the topics of the FASEB symposia. These developments are described in more detail in Federation Proceedings. Manuscripts containing original commu- nications, or proposals for reviews, should be sent to the Editor-in-Chief, Dr. W. J. Whelan, Federation Proceedings, P.O. Box 016129,Miami, FL 33101, USA.

Vol. 29, No. 5. 1986 195 Committee Report Sections. The LRPC suggested that in ad- This week, reports were submitted from dition to the regular officers, each Section the Sections on (1) The Nervous System, elect a representative to SAC just as they (2) Environmental, Thermal and Exercise do for the Program Advisory Committee. Physiology, and (3) Renal Physiology. The Section Advisory Chair informed the three Section represen- III. Responses of the SAC to the LRPC tatives that their sections received five-year I. Approval of Minutes Recommendations approval. In the Fall 1986, the Respiratory, Endocrinology and Metabolism, and Car- The minutes of the October 13, 1985, A. There was general agreement that diovascular Sections will be asked to report meeting of the SAC were approved as dis- there was undue rigidity in the organiza- to Council. All remaining Sections will be tributed. tional practices recommended by the LRPC reviewed within the next year and one- with respect to the operation of Sections. half . II. Report by the Chair on the Meeting of Some Sections found that communication One of the major concerns expressed the Long-Range Planning Committee with the membership by mail (i.e., news- by Council after hearing the reports was letters) was very effective and prefer this that the Sections were not operating in full In answer to the charge of Council, the to formal business meetings. Others felt compliance with their bylaws. The Chair LRPC met on Saturday, April 12, 1986, to that there was no need for business meet- recommended that it would be prudent to discuss issues related to the organization ings where present operating procedures make clear in future reports the full extent of the Sections and the SAC. The Chair of was satisfactory. of Section activities and its specific gover- SAC attended this meeting. The LRPC B. Many Sections supported the idea nance practices, and cautioned Sections to made the following recommendations to that the Chair of each Section should serve Council: implement the latter, if not already done. as representative to the SAC. Under the It was also noted that there was no stand- A. Organization of Membership present governing bylaws, it would be ard format for such reports and that it is 1. Sections: a group of more than 100 nearly impossible to accomplish this. It Regular members of the Society encom- difficult to anticipate the expectations of was decided, therefore, that the Section Council. (The Chair of SAC requested that passing an area of scientific investigation members would be consulted regarding Council provide this during her report to of physiological mechanisms. Sub-sections the merit of having Section Chairs serve a them on April 16, 1986.) representing areas of special interests three-year term, with the President-elect within the general domain of interest of attending the SAC meetings as observer in the section may be formed, with no limit V. Discussion With Dr. Knox (President- the third year to ensure continuity. These Elect) on membership. details would be worked out by the Sec- 2. Groups: a significant fraction of the tions. At the present time, there seemed to Dr. Knox was invited to join the Com- membership sharing common interests be no strenuous objection to having a Sec- mittee and presented a brief outline on that encompass an area of physiology of tion Chair serve for an extended time, in some of the suggested plans of gover- sufficient breadth extending beyond a sin- contrast to the view of the LRPC. nance. gle section, and possibly overlapping the C. With respect to the suggested need The SAC unanimously requests that interests of multiple sections. to consolidate Sections, the members felt Council provide it a copy of its governance Every member of APS is encouraged to that anv action on this item at this time proposal for review PRIOR to its discus- choose a Section with which they want would be premature, because the final tal- sion at a JOINT meeting of the SAC and PRIMARY affiliation. This does NOT pre- lies are not complete on Section affilia- Council and PRIOR to its presentation to clude membership in any Group. All vot- tions. A follow-up on the questionnaire the membership. ing and governance matters would be con- sent to the APS membership is requested The SAC unanimously agreed that it ducted through the Sections. That is, from the APS office. could serve the Society well as a nominat- Groups would not have representation on Further, it was generally agreed that the ing body for the election of Society offi- the SAC. However, representation on the Sections, as they currently exist, appear to cers. (These points were reported to Coun- Program Advisory Committee would in- satisfy the needs and scientific interests of cil by the SAC Chairperson on April 16, clude Sections as well as Groups. the constituents. There appears to be no 1986.) B. Consolidation of Sections reason to arbitrarily force the combination The suggestion was made that there is a of Sections using Section titles that would VI. SAC Plan for Governance of Sections need to consolidate sections where there appear to encompass common interests of is considerable overlap of disciplines. two populations that in reality are dissim- Several members of the SAC indicated C. Section Governance ilar. that it was important for the SAC to have There is a need to tailor the structure (Note: these ideas were conveyed to input regarding the guidelines for the or- ganization and governance of the Sections, and operation of Sections to assure demo- Council by the SAC Chairperson during cratic procedures. If Sections are to play a her report to Council on April 16, 1986.) and a task force for this purpose was orga- role in governance then the democratic nized bv the Chair. The members of the task force are Drs. Blake Reeves (Chairper- input of the membership is mandatory, and IV. Reports on Section Activities mechanisms not already in place must be son), Larry Sullivan, Norman Weisbrodt, implemented toward this end. Emphasis According to the Operational Guide of and Loring Rowell. was placed on the need for business meet- the APS, the existence of a Section is sub- ings and strong lines of communication ject to review every five years. As part of VII. Election of SAC Chair with the membership. the review process, each Section must sub- mit a written report on its operation and This is deferred until the October 1986 D. Section Representation on SAC meeting. The term of a representative on the SAC activities to Council and its representative is three years, a period that does not now must appear before Council to discuss the match the term of Chair of any of the report. Marion Siegman, Chair THE PHYSIOLOGIST Doctor of Science degree from Brown Uni- versity (19621, President of the Federation 3 5TH PRESIDENT of American Societies for Experimental Bi- Hymen Samuel Mayerson ology (19631, and election to membership in the National Academy of Science (1900-1985) (1963). He served on the editorial boards of both the American Physiological Society Hymen S. Mayerson, former President of and American Heart Association. He was a the American Physiological Society, died member of the Board of Directors of both on September 30, 1985, in New Orleans, the American Heart Association and Amer- soon after celebrating his 85th birthday. ican Cancer Society. Hy gave generously He was born on September 10, 1900, in of his time to volunteer agencies. Providence, Rhode Island, of immigrant In the last six to seven years of his life, parents from central Europe. He had his Hy became quite limited from a series of primary and secondary education in Prov- cardiovascular problems while retaining idence and then entered Brown University clear mental faculties to the end. He had to study biology. After receiving his Bach- fairly extensive peripheral vascular dis- elor’s degree from Brown, he started grad- ease, causing him to become physically uate work in physiology at Yale. Hy re- limited in walking and in gardening, which ceived his Ph.D. degree in 1925. Henry he enjoyed doing. In August 1985 he had Laurens, one of the more senior depan- a myocardial infarction and presumably ment members, was invited to take the again on the night of this death. In his last Chair of Physiology at Tulane one year year Hy confided in his son Peter that he later, and he invited young Mayerson to wasn’t afraid of dying and, in his character- accompany him as a member of the de- globulin turnover and their relationship to istically calm and philosophical manner, partment. In New Orleans, Hy met his plasma proteins leaked from the circula- said that he felt that it was fitting that he wife, Caroline, with whom he had two tion emanated. would probably die of failure of his circu- children, Peter and Mary. After Hy retired as Chairman of the Phys- latory system-the system that he had Hy became Chairman of the Department iology Department, he took a full-time po known and studied so well for most of his of Physiology at Tulane University School sition as associate director in charge of professional life-“much better that, than of Medicine in 1945 and continued in that research and education at Tour0 Infirmary, a stranger like cancer.” position until 1965 when, at the age of 65, the second largest hospital in New Orle- Hy was a warm and gentle person. He he retired. He was a stabilizing factor on ans. He continued in this position for 10 was a marvelous teacher and provided the the Tulane faculty. In 1951, the New Or- years, when he again retired. However, Hy major component of the teaching in phys leans Item published a profile of Hy May continued to work on a voluntary basis on iology at Tulane for about 20 years. He was erson as an educator. In the opening par- the Board of Trustees of Dominican Col- a master in the use of demonstrations for agraph, it stated, “When Tulane University lege in New Orleans for several years and teaching. Whether the results turned out establishes an award for the ‘most cooper- served as the chairman of the committee “according to the books” or catastrophe ative member of the Tulane faculty’ there that recruited its president. He was struck from a loose cannulation, he made is little doubt that the first recipient will awarded its Gold Medal of Service in 1980. his teaching points while also being enter- be Hymen Samuel Mayerson, Ph.D.” Yes, Hy also continued to work on the Senior taining. Thus he is remembered well by when a cool head was needed to resolve a Physiologists’ Committee with Bruce Dill, many medical students and graduate phy serious problem, the Dean called on Hy. generating correspondence with retired sicians, who often returned to Tulane for The hottest issue of the mid-1950s at Tu- physiologists, which made interesting Hy’s postgraduate course in circulatory lane was the planned new building to al- reading in The Physiologist. physiology. Undergraduate and postgrad- low the basic science departments of the Hy received many honors during his uate students as well as his faculty recog- Medical School, then housed on the up long and illustrious career including elec- nized him as a wise man to whom one town campus in the Richardson building, tion to the Presidency of the American could turn to discuss both personal prob- to move downtown with the rest of the Physiological Society (1%2), honorary lems and those relating to science. It is Medical School. Hy was put in charge of this characteristic for which this physiolo- the building committee and in this way gist and gentle man was especially ad- made one of his more lasting contributions mired and respected. to Tulane. In recognition of the trust that people Hy’s research interests were in circula- had in him to perform excellently for the tory physiology, and he had particular in- well-being of his family, friends, school, terest in blood volume regulation. It was and professional societies, he wasasked to under Hy Mayerson’s tutelage and guid- perform service and give advice for many ance that work on using lymphatics to purposes. His legacy to the American Phys- study capillary permeability was started in iological Society was his good judgment at the Physiology Department of Tulane. By the times when important decisions using appropriately labeled macromole- needed to be made and the gentle but firm cules and studying the kinetics of their direction which he provided. Hy is sur- disappearance from blood and appearance vived by Caroline, Peter, and Mary. in lymph, a new understanding of the role of lymphatic and interstitial albumin and Karlman Wasserman

Vol. 29. No. 5, 1986 197 AI’S MEMBERS ONR Restoration of (Continuedfrom p. 189) ( Continued from p. 191) Stephen Hales’ Grave, one of the six Councillors shall be from in this program has been positive and re- Teddington, London the same institution, and no more than two assuring. Basic research projects that have of the six shall have primary affiliation with a reasonably high risk for success often Stephen Hales (1677-1761) was an em- the same Section. stimulate considerable excitement. The inent English physiologist of the early The proposal recommends a simplifi- principal investigator can be more specu- eighteenth century. He is best known for cation of the voting process. Voting will be lative, and the monitoring by a single Sci- making the first measurement of blood by mail ballot where each regular member entific Officer of progress on a contract pressure, but he also made important con- shall mark an “x” for each open office with can provide valuable feedback for planning tributions to respiratory and plant physiol- no ranking required. In a typical ballot, and funding future experiments. In addi- ogy. He was the minister of St. Mary’s there will be five candidates for Councillor tion, it is an operating procedure in the Church in Teddington, near London, for (vote for two), and two candidates for Pres- ONR that the Scientific Officers maintain over 50 years and is buried under the tower ident-Elect (vote for one). their personal expertise in science. To that that he built. Recently, his grave fell into It is important to note that special inter- end, most individuals have adjunct faculty disrepair and a worldwide appeal was est groups (without qualifications or inter- appointments or similar arrangements that launched for funds to refurbish it. The est in Section status) will continue to be permit them to conduct, at a reduced scale, American Physiological Society made a encouraged and have input to program- ongoing laboratory research projects and modest contribution, and a ceremony ming. to continue to publish. This is expected to marking the restoration of the grave was We would be most pleased to receive contribute to their ability to administer held at the church on June 22, 1986. The comments and suggestions concerning science research. church is well worth a visit and is easily this proposal for restructuring APS gover- In summary, the preproposal screening reached by suburban train. It remains nance. At each step of the way, the pro- mechanism greatly reduces the time and much as it was in Hales’ time and has a posal has been strengthened by the careful effort spent writing unsuccessful full- fine stained glass window commemorating consideration of those that have reviewed length applications. Formal proposals, sub- its famous minister as well as parish rec- it, and we look forward to the input from mitted with or without a preproposal, are ords in Hales’ hand. @ the membership at large. As I stated in the reviewed for responsiveness to program editorial in the August issue of The [email protected] goals of the navy as well as for merit. iologist, if approved by membership, we Because of this, the ONR normally does Conference on will adopt the new governance plan at the not raise many of the funding priority is- Laboratory Animals Centennial meeting, hopefully an appro- sues found in federal agencies that are priate birthday present for the Society. required to consider any and all applica- A conference provisionally entitled “An- Thanks very much for your help. tions for research support. imal Pain: Its Recognition, Alleviation, and Finally, as the ONR celebrates its 40th Avoidance” will be held June 5-6,1987, in anniversary and the American Physiologi- Chicago. It is jointly sponsored by the Sci- cal Society approaches its 100th year of entists Center for Animal Welfare and the activity, it is appropriate to acknowledge University of Chicago. Practical, ethical, the support for physiology research pro- and philosophical issues of animal re- vided by the ONR since its founding in search that involve pain will be addressed. PUBLIC AFFAIRS 1946. This agency has earned a special Information: Dr. F. Barbara Orlans, Direc- ( Continued from p. 192) place in the history of our interesting sci- tor, Scientists Center for Animal Welfare, “Past research by physiologists has led ence. @ 4805 St. Elmo Avenue, Bethesda, MD to new procedures in blood transfusions; 20814; phone: (301) 654-6390; or Dr. Lee modern anesthesia; treatments for rabies Cera, Director of Animal Care, the Univer- and small pox; vaccines for tetanus, polio, sity of Chicago, 5801 Ellis Avenue, Chi- and measles; and the discovery of antibiot- cago, IL 60637; phone: (312) 962-9361. ics and penicillin. More recently, the un- derstanding of physiology has made essen- tial contributions to the development of Call for Historic Films organ transplants, procedures for artificial heart implantation, and the discovery of DNA. It has been suggested by Dr. A. P. Fishman, Chairman of the Centennial Commit- “During the week of March 29,1987, the tee, that at the APS Centennial Meeting in 1987 there be a continuous showing of American Physiological Society will spon- historic films in physiology. A few such films are already available to APS. For sor a scientific and educational convoca- example, a film taken at the International Physiological Congress in Boston, 1929, tion in Washington, DC, that will be at- has recently been donated. A film on Pavlov has been offered, and APS already has tended by internationally renowned phys- iologists, including Nobel laureates. I a copy of the classic film of August Krogh on microcirculation in the frog. Other hope that my colleagues will join with me films illustrating the history of physiology are desired. If you know of a film of in sponsoring this resolution to give historic interest that can be borrowed for the Centennial-either a film that traces proper recognition and encouragement to a historical development, such as the well-known film on Harvey and the circulation those involved in such an important area of the blood, or an old film, such as the Krogh film mentioned above, which by its of knowledge and research as physiology.” association with a famous physiologist has become historic-please write to Dr. Toby Appel, Historian/Archivist, American Physiological Society. William M. Samuels, CAE

198 THE PHYSIOLOGIST by our current society to physiologists. Congress and satellites from the National This calls for discussions on postgraduate Societies of Physiology and corresponding IUPS NEWS education and training of physiologists. organizations as well as from the IUPS It is in the interest of the organizers to Commissions. General Assembly host a special course for physiologists from Secretaries of the National Physiological the developing countries to promote the Societies and corresponding organizations The General Assembly of IUPS met on use of applications of present knowledge as well as those of IUPS commissions will the campus of the University of British to serve these nations. be kept informed about the progress of the Columbia in Vancouver July 13,1986. One A number of satellite symposia are ex- Congress arrangements. of the major decisions made by the dele- pected to take place in Finland and neigh- For further information write to Profes- gates was the approval of a new constitu- boring countries within the framework of sor Osmo Hinninen, Secretary General, tion and bylaws of the IUPS, which will the Congress. P.O. Box 722, 00101 HELSINKI, Finland, move the international congresses and the The organizing Committee will collect Telex 122529 trex sf. meetings of the General Assembly to a suggestions for the scientific program of quadrennial cycle after 1989. Other items discussed and approved by the delegates were the locations of future congresses. The invitation by the Finnish The Ohio State Science Fair Physiological Society to host the XXX1 International Congress in Helsinki July 9- The vitality of our research endeavor achievement in the physiological sciences. 15, 1989, was confirmed. The invitation of depends on our ability to stimulate young The first-place awardees also received a The Physiological Society was accepted minds to pursue research careers. To inter- copy of the book Circulation of the Blood. subject to confirmation at Helinski. est young scientists in physiological re- Men and Ideas, by A. P. Fishman and D. The new members elected to the IUPS search, students must be exposed to op W. Richards. The APS judges for the event Council for the period 1986-1989 are Pres- portunities in which they view physiology were Charles W. Smith and K. M. Hanson, ident, A. Huxley (United Kingdom); Vice- as a stimulating science. To assist in the members of the Department of Physiology, President, D. Denton (Australia); Vice- stimulation of young minds, the American Ohio State University. President, C. Crone (Denmark); Secretary Physiological Society sponsored several The APS hopes to sponsor future awards (until 12-31-86), J. Scherrer (France); Sec- awards at high school science fairs. The at the Ohio State Science Fair and would retary (after l-1-87), R. Naquet (France); first of these awards were given at the Ohio be pleased to sponsor similar awards at Treasurer, H. Valtin (United States); X. State Science Fair, which was held on April State Science Fairs in other states. Individ- Aubert (Belgium); R. Berne (United 19, 1986, at Ohio Wesleyan University in uals who are actively involved with the States); T. P. Feng (China); E. Fromter Delaware, Ohio. The APS joined approxi- event in their states should contact Martin (West Germany); M. Gerova (Ctechoslo- mately 40 other associations, institutions, Frank, Executive Secretary-Treasurer, APS, vakia); M. Ito Clapan); P. Kostyuk and societies in sponsoring awafds for the to discuss mechanisms by which the APS (U.S.S.R.); K. Kmjevic (Canada); R. Ra- State Science Day sponsored by the Ohio can undertake activities in those states. It hamimoff (Israel); R. Rodriguez (Argen- Academy of Science. The APS sponsored is hoped that such activities will provide a tina). first- and second-place awards for grades stimulus to young minds interested in pur- 7-9 and 10-12. Each of the awardees re- suing careers in physiological research. @ Finnish Physiological ceived a certificate in recognition of their Society to Host XXX1 International Congress

The Finnish Physiological Society, So- cietas Physiologica Finlandiae, invites world physiologists to a centennial meet- ing in the XXX1 International Congress of Physiological Sciences, July 9-15,1989, in Helsinki. The program of the Congress under planning will consist of a number of in- vited Centennial Frontier Lectures to re- view the achievements in various areas of physiology. Two other components of the Congress will be symposia and oral as well as poster communications. Communica- tions can be submitted either to comple- ment symposia or included in special free poster sessions. The main aim of the con- gress is to encourage free dissemination and exchange of information. During the Congress, time is also de- Second me, I@ to rJ#& C. W. Smith, Daniel &uenstein, K. M. Hanson, and JeffWarner. voted to examine the challenges presented Fronr me, lop ro tfg6t Car&e Nigh and Tracy kbgast. Vol. 29, No. 5,1986 USOC Conference on Sports Joint Meeting on Cellular ANNOUNCEMENTS Medicine/Science for Dynamics Disabled Athletes The EuropeanClub for Muscleand Motility Biotechnology in Clinical TheU.S. Olympic Committee’s Committee on andthe EuropeanCytoskeletal Club will hold a Medicine Sportsfor the Disabledhas announced plans to joint meetingon CellularDynamics on August holda conferenceon sportsmedicine and sports 30-September2, 1987,at KibbutzAyelet Has- hahar,Galilee, Israel. Tentativetopics to be The International Symposium BIOTECH RIA sciencefor disabledathletes on March26-28, discussedinclude the molecularbasis for me- 87 on Biotechnology in Clinical Medicine will 1987,in the Mt. WashingtonValley ResortArea, NewHampshire, adjacent to the NationalHand- chanochemicalprocesses in living cells,the as- be held in Rome, Italy, at the Hotel Cavalieri semblyand interactions of cytoskeletaland con- Hilton International on April 13-15, 1987. Top- icappedSport and RecreationAssociation’s Na- tional Championships.The conferenceis in- tractile systems,molecular and structuraldy- icsinclude Biotechnology in CardiovascularDis- namicsof the cytoskeleton(cell cycle,cell com- eases,Towards New Vaccinesand Immunodi- tendedto educatethose who work with disabled personsabout recreationaland competitive munication,intracellular transport), muscle con- agnostics,Bioactive Carriers,and Current tractionand its regulation,genetic and devel- Trendsin Biotechnology. sportsopportunities for disabledpersons and to provide informationabout significantsports opmentalaspects of cytoskeletaland contractile Information:Organizing Secretariat Fonda- elements,and pathologicalmodulation of con- zione Giovanni Lorenzini,Via Monte Napo- medicineand sciencepractices and concepts and their applicationto athleteswith a wide tractileand cytoskeletal systems. Information: A. leone, 23, 20121 Milan, Italy. Phone:(02) Oplatka,Dept. of PolymerResearch, The Weiz- 70.22.67/78.38.68. rangeof disabilities.A call for papershas been issued;deadline for receiptof abstractsis De- mann Institute of Science,Rehovot, Israel. cember1, 1986. Information:Mary Margaret Telex: 361900.Phone: 08-483362. Douglass Project for Rutgers Newsom,U.S. Olympic Committee, Department of EducationServices, 1750 East Boulder Street, Women in Math and Science ColoradoSprings, CO 80909-5760. Phone: (303) Conference on Noise 578-4546. in Physical Systems DouglassCollege, the women’sundergradu- ateunit of Rutgers-TheState University of New TheNinth International Conference on Noise Jersey,announces a new endeavor to encourage Availability of Request in PhysicalSystems is plannedfor May 25-29, youngwomen to persistin math and science for Applications - 1987, at the Universitede Montreal.The confer- fields:the Projectfor RutgersWomen in Math encewill includefluctuations in biologicalsys- andScience. TheDivision of LungDiseases of the National temsand membranes and will be the 5th in the Douglasshas been awarded a three-yeargrant Heart, Lung,and Blood Instituteinvites grant seriesof conferenceson l/f noise.The funda- fromthe NewJersey State Department of Higher applicationsfor a singlecompetition for support mentalaspects of noise,such as physicaland Education’sFund for the Improvementof Col- of researchon the roleof neurochemicalsin the biologicaltransport problems, links to statistical legiateEducation. The project is multifaceted controlof respirationin healthand disease. mechanicsand stochastic processes, as well as andwill includea SummerScience Institute for The mainpurpose of this specialgrant pro- the importantimplications of noisein modern high schoolstudents, orientation programs for gramis to stimulatenew and innovativebasic electronicdevices and other physicalsystems, newlyadmitted students to the undergraduate researchdirected at identifyingthe endogenous will be considered.Papers are being requested; collegesat Rutgers-NewBrunswick, peer study neurochemicalsand hormonesthat act to con- extendedabstracts must be receivedby January sessions,support groups, career workshops of- trol breathing,mapping their cellularnetworks, 10,1987.Information: Dr. CarolynVan Vliet, 9th feringjob survival skills and specific information elucidatingtheir actions,and the mechanisms InternationalConference on Noisein Physical aboutcareer options, special seminars to discuss by whichthey work.Among the disciplinesand Systems,Centre de RecherchesMathematiques, ongoingwork and socialissues of womenin expertisethat may be appropriatefor this re- Universitede Montreal,C.P. 6128,Succ. “A”, science,courses in the Women’sStudies pro- searchprogram are respiratory physiology, neu- Montreal(Quebec) Canada H3C 357. gramfor mathematicsand sciencestudents, ad- robiology,molecular biology, neuroanatomy, vising gearedspecifically toward careersfor biochemistry,endocrinology, and pharmacol- womenin industry,government, and academia, ogy. and coordinationof internshipand externship A letter of intent is requestedby December LSRO Releases Report on placementinformation. An importantpart of our 15,1986; the deadlinefor receiptof applications Neurotoxicity and interventionwill be to havementors available is March16, 1987. Awardsin connectionwith Behavioral Dysfunction to studentsand also to presentstudents with this announcementwill be madeto foreignin- role modelsof womenachievers in mathand stitutionsonly for researchof veryunusual merit, Underthe termsof a contractwith the Food science. need,and promise, and in accordancewith Pub- and Drug Administration(FDA), the Life Sci- Informationon beingspeakers, mentors, and lic HealthService policy governing such awards. encesResearch Office (LSRO),Federation of role models:Director Dr. Ellen F. Mappen, Requestsfor copiesof this RFA shouldbe AmericanSocieties for ExperimentalBiology Women’sStudies, DouglassCollege, New addressedto James P. Kiley,Ph.D., Structure and (FASEB)has completed a studyexamining the Brunswick,NJ 08903. Phone: (201) 9329197. FunctionBranch, Division of Lung Diseases, scientificissues related to neurotoxicityand be- NHLBI, 5333 WestbardAvenue, Room6A07, havioraldvsfunction. The LSROreport entitled Bethesda,MD 20892.Phone: (301) 496-7171. “PredictingNeurotoxicity and BehavioralDys- AAALAC Appoints Executive functionfrom PreclinicalToxicologic Data” pre- Director sentsseven commissioned symposium papers Cerebral Hypoxia andthe viewsand opinions of an LSROad hoc TheAmerican Association for Accreditationof and Stroke expertpanel. It reviewsthe availabilityof neu- LaboratoryAnimal Care announces the appoint- rotoxicity datafrom conventionalapplied toxi- ment of Albert E. New, D.V.M., as Executive A satellitesymposium on CerebralHypoxia cologytesting and identifiesadditional screen- Directorof AA&AC, effectiveOctober 1, 1986. and Stroke:Reversible and IrreversibleEffects ing andresearch needs for improvingthe relia- Plansfor the Associationto moveto the head- andTheir Prevention is planned for August1987 bility and comprehensivenessof the prediction quartersbuilding of the Federationof American in Budapest,Hungary after the 2ndWorld Con- of sucheffects in humans.Copies of the report Societiesfor ExperimentalBiology, 9650 Rock- gressof Neuroscience.Information: G. Somjen, maybe purchased($25 per copy postpaid) from ville Pike,Bethesda, MD, areunderway, and Dr. Dept. of Physiology,Duke University Medical the FASEBSpecial Publications Office, 9650 Newwill be in residencethere. Center,Durham, NC 27710. RockvillePike, Bethesda, MD 20814.

THE PHYSIOLOGIST PEOPLE AND PLACES . . . OPINION

R. Kent Hermsmeyer, Ph.D., Professor of 15th honorary degree, a Doctor of Science, Pharmacology, University of Iowa, has from St. Mary-of-the-Woods College in In- To the Editor been appointed Chair of the Department diana. An APS member since 1962, she of Physiology, University of Nemda. An chaired the Task Force on Women in Phys The many recent articles and editorials APS member since 1972, Dr. Hermsmeyer iology. in The P@sio/og& [most recently The wasawarded the Bowditch Lecture in 1982. Juha P. Kokko, Pbysiologisr 29(3): 43-44, 19861, FASEB APS member Roger A. Davis, Ph.D., Pro- M.D., Ph.D., has been newsletters, Federation Proceedings, and fessorof Physiology at Louisiana State Uni- named Chair of the elsewhere on the animal rights movement versity, has been appointed Professor of Department of Medi- have been largely concerned with the Medicine and Physiology at the University cine, Emory Univer- threat this movement poses to research in of Colorado. sity, effective Septem- the biological sciences. This is important, C. Kern Wilde&al, M.D., Ph.D., has ber 1. Dr. Kokko, For- but insufficient by itself. Many laymen are been named President of the University of mer Professor of In- hostile or indifferent to science. Others Texas Health Science Center at Dallas. Dr. ternal Medicine and believe, beyond all arguments to the con- Wildenthal, formerly Dean of the South- Chief of Nephrology trary, that computers can replace animals. western Medical School, University of at the University of Texas Health Science I propose the following two additional Texas at Dallas, has been a member of the Center at Dallas, has been a member since measures against the animal rights move- Society since 1971. 1973. ment-one a most reasonable proposal, APS member Edward H. Blame, Ph.D., Bdward Taub, APS member since 1971, one an argument. has moved from Merck Institute for Ther- has accepted a position as Professor of We should propose that laws prohibiting apeutic Research to Searle Research and Psychology at the University of Alabama, pounds from releasing animals for any pur- Development Division of G. D. Searle & Birmingham. pose other than pet adoption should also Co. as Director of Cardiovascular Pharma- David H. Cohen assumed the post of Vice prohibit pounds from killing animals in cology. A member since 1975, Dr. Blaine President for Research and Dean of the their possession. Many laymen do not has been very active in Society activities. Graduate School at Northwestern Univer- know that unplaced animals are routinely Harvey Sybers, M.D., Ph.D., Professor of sity, effective September 1. He will also destroyed. They support these laws be- Pathology and Laboratory Medicine at the hold professorships in the Department of cause they are against killing animals (read University of Texas Medical School at Neurobiology and Physiology in the Col- dogs and cats), not because they are op- Houston, is the recipient of the 19% John lege of Arts and Sciences and in the De- posed to research. Those animal rights ad- Freeman Faculty Teaching Award, which is partment of Physiology in the School of vocates, who are not so much for animals given annually to the outstanding basic Medicine. Dr. Cohen was elected to Soci- as against science, as shown by their will- science faculty member by the senior class. ety membership in 1969. ingness to allow pounds to destroy un- Dr. Sybers was elected to APS membership APS member FrancisJ. Locke, Professor wanted animals, will be given the choice in 1973. of Medicine at the State University of New of revealing their true purpose by oppos- M. Elixabeth Tidball, Professor of Physi- York at Buffalo, has been named President- ing this restriction while still favoring such ology at the George Washington University elect of the American College of Cardiol- laws, of abandoning their advocacy of such Medical Center, was recently awarded her ogy. 6 laws, or of accepting the overcrowded pounds and shortage of facilities for stray pets that will follow passage of laws with this restriction. We should emphasize the need for ani- mals in the education of physicians and BOOKS RECEIVED surgeons. The animal rights advocate, who blithely proclaims that the use of animals Acid-Base Regulation in Animals. N. Heisler Feedbackand Motvr Controltn hwertebrates is unnecessary and immoral, may be si- (Editor). Amsterdam: Elsevier, 1986, 492 pp., and VertekratesW. J. P. Barnes and M. H. illus., index, $129.75. Gladden (Editors). New Hampshire: Croom lenced by the prospect of being operated Diabetes and Pregnancy. Teratology,Taxicity Helm, 1986,4% pp., illus., index, $69.00. on by a surgeon with no prior experience and Treatment. 1. Jovanovic, C. M. Peterson, MolecularCell Biohgy. J. Dar&l, H. Lodish, with living tissue. and K. Fuhrmann (Editors). New York: Praeger, and D. Baltimore. New York: Freeman, 1986, 1986,440 pp. illus., index, $72.50. 1187 pp., illus., index, $42.95. Stephen R. Cohen LIiagnastic Microbiology S. hi. Finegold and Neurometbodc4. ReceptorBinding. A. A. New York State E.J. Baron. St. Louis, MO: Mosby,1986,914 pp., Boulton, G. B. Baker, and P. D. Hrdina (Editors). Institute for Basic Research illus., index. Clifton, New Jersey: Humana, 1986, 576 pp., Digestion and the Structure and Function of illus., index, $64.50. tke Gut. D. F. Magee and A. F. Dailey II. Basel: RecentAcbievetnents in RestomtiveNeurol- Karger, 1986,359 pp., illus., index, $63.00. ogy. 2. Rvgresive Netaumus~uhr LMseasex M. Embpgenesis in Angie A Develop- R. Dimitrijevic, B. A. Kakujls, and G. Vrbova mental and Experimental Study. V. Raghavan. (Editors). Basel: Karger, 1986, 360 pp., illus., New York: Cambridge University Press, 1986, index, $155.00. 303 pp., illus., index, $39.50. Stressand Anxiety, Vd 10.A Sourcebookof Exercise and Sport SciencesReviews Volume Tbeq and ResearcAC. D. Spielberger and 1. 24. K. B. Pandolf (Editor). NewYork:Macmillan, G. Sarason(Editors). New York: Hemisphere, 1986,457 pp., illus., index, $39.95. 1986,4% pp., illus., index. dB Vol. 29, No. 5, 1986 Centennial Update

By now, nearly everyone knows that the highlight of the APS being produced. Among these are a plate, cup, and a tile with Centennial year will be the celebration in Washington, DC, the logo. The prices of these items will be modest. March 29 to April 3, 1987. The Federation of American Socie- All members of the American Physiological Society will ties for Experimental Biology (FASEB), which is also celebrat- receive a copy of the Society’s Centennial history, edited by ing a birthday in 1987----its 75th, is lending a large hand in John Brobeck and Orr Reynolds. In addition, the Society will making the Centennial a success. One of FASEB’s contribu- offer for sale an historical volume, edited by Gerald Geison, on tions has been the adoption of the American Physiological physiology in the American context, 1850-1940, based on a Society’s theme for the week-long meeting: A Century of Prog- workshop sponsored by the American Physiological Society ress. Symposia and special lectures will develop this theme; and held at the National Library of Medicine in January 1986. penetrating reviews will examine the growth of ideas and tech- Finally, FASEB and each of its constituent societies are coop- niques and the new horizons in physiology will be explored. erating with the American Physiological Society to produce a Exhibits and demonstrations will round out the picture. The 32-page illustrated publication on the founding of the American constituent societies of the Federation will also reflect on their Physiological Society, the Federation societies, and the Feder- own origins as offshoots of the American Physiological Society, ation. FASEB plans to publish this material in Federation emphasizing the shared underpinnings of the biological sciences Proceedings immediately before the meeting and a free reprint and the continuing interplay of the societies. will be made available to everyone attending the Founders In honor of the founders of the American Physiological Week meeting in Washington. Society, the week in Washington has been designated as Foun- It is anticipated that several scholarly, governmental, and ders Week. In recognition of the fact that the celebration was industrial organizations will join in honoring the birth of the dedicated not only to a look backward but to a look ahead, a American Physiological Society through exhibits at the meet- Second Century Founders Program has been created. Funds ing. One notable exhibit in the National Library of Medicine contributed to this program will be devoted primarily to support will depict 100 years of physiology. the educational and scientific programs planned as part of the The many threads that form the fabric of the Centennial Centennial Celebration. In the brief period since this program Celebration in Washington are coming together. The few loose was launched, members have contributed more than $24,000 to ends seem to be manageable. The Centennial Committee urges the fund. you to mark your calendar so that you may share in this unique Memorabilia are an essential part of a centennial celebration. occasion. A Centennial medallion has been cast. One side features the Please feel free to offer advice or to request clarification by faces of the five founders; the other carries the Centennial logo. writing to Dr. Alfred P. Fishman, Centennial Celebration Com- The medallion is very attractive and has already generated mittee, The American Physiological Society, 9650 Rockville great interest among collectors and those interested in a sou- Pike, Bethesda, MD 20814. venir of the Centennial Celebration. Other memorabilia are

202 THE PHYSIOLOGIST Know Your Sustaining Associates

American College of Surgeons DaganCorporation Schering-Plough The American College of Surgeons is an Dagan Corporation manufactures elec- Born out of a 1971 consolidation of two association of surgeons organized for the tronic instruments used in electrophysiol- companies- Plough, Inc. and the Schering primary purpose of improving the quality ogy. Dagan offers a full line of analog and Corporation -Schering-Plough is dedi- of care for the surgical patient by elevating digital products, including preamplifiers cated to the discovery, development, and the standards of surgical education and for use in intracellular and extracellular marketing of novel therapeutic entities. practice. In the pursuit of its goals for recording, single and two electrode volt- The company focused its research in the seven decades, it has profoundly influ- age/current clamps, patch clamps/whole- fields of anti-inflammatory, antiallergic, enced the course of scientific surgery in cell clamps, signal averagers, programma- cardiovascular, and anti-infective disor- America. ble multichannel stimulators, and ionto- ders. The company has also attained a lead- The College has been a pioneer in es- phoresis generators. ing position in immunology and recombi- tablishing a nationwide program for hos- nant DNA technology. pital accreditation, in developing standards for the training of surgical residents, in HarvardApparatus Stuart Pharmaceuticals setting guidelines for a high level of pre- Harvard Apparatus, since its inception Stuart Pharmaceuticals, division of ICI operative and postoperative care, and in in 1904 at the Harvard Medical School, Americas, Inc., is one of the youngest re- organizing the resources of surgery in a continues to design, develop, and study search-based companies, founded in Pasa- major effort to improve the care of the the unique apparatus that has shaped the dena, CA, in 1941. critically injured accident victim and the development of teaching and research in Now headquartered in Wilmington, Del- patient with cancer. physiology and allied science, including aware, Stuart is linked to the worldwide Moreover, since its founding in 1913 the syringe peristaltic and respiration pumps, pharmaceutical research efforts of Imperial college has continuously and publicly de- recording systems, and research accesso- Chemical Industries, PLC, of London, with nounced fee splitting, unjustified opera- ries. which it merged in 1972. These efforts tions, itinerant surgery, and other practices have produced some of today’s most im- detrimental to the welfare of patients and Medtronic portant therapeutic agents such as the prin- the public and has made adherence to its Medtronic, for a quarter century the cipal P-blocker for cardiovascular disease, principles of surgical ethics a condition for world’s leading implantable medical de- the most widely prescribed single agent obtaining and maintaining Fellowship. vice company, today serves a broad cardi- for breast cancer, and the leading antisep- ovascular marketplace. Growing capabili- tic used in hospitals. The AmericanMedical Association ties in screening, diagnosis, and follow-up Current research promises to yield in- The American Medical Association pro- care now complement established thera- novative products for infectious disease, motes the art and science of medicine and peutics businesses such as heart pace- anesthesia, heart disease, cancer, and dia- the betterment of public health. The AMA makers and valves. Also, for over a decade betes. accomplishes this mission by advancing Medtronic has applied expertise in the standards of medical education, promoting electrical functions of the body to neuro- The Upjohn Company support for biomedical research, repre- logical stimulation products. The Upjohn Company, a multinational senting the medical profession, providing corporation headquartered in Kalamazoo, information about medical matters, and Merrell Dow ResearchInstitute MI, is celebrating its centennial year as a upholding professional conduct and per- Merrell Dow Research Institute, with maker of fine pharmaceuticals. It is one of formance. centers in four countries and headquarters the I5 largest research-based pharmaceu- tical manufacturers in the world. It has Coulbourn Instruments in Cincinnati, OH, is an interdisciplinary research, production, and warehousing fa- Coulbourn Instruments, Inc. manufactures institution engaged in both basic and ap- plied biomedical research. The institute cilities in more than 45 countries and its electronic instruments for in vivo life sci- products are sold in more than 150 coun- ence applications. Products include the identifies new targets and molecules that may be suitable for pharmacological inter- tries. LabLinc Modular Instrument System for Upjohn has long been committed to the physiological signal conditioning, experi- vention with an ultimate goal of develop- ing new therapeutic agents. research, development, manufacture, and ment control, and data acquisition, featur- marketing of pharmaceuticals. Human ing over 100 modules, including computer health care is the heart of Upjohn’s en- interface ports, signal conditioning and NarcoBio-Systems deavors. processing, and counting and timing mod- Narco Bio-Systems designs, manufac- ules for chart and computer-based poly- tures, and distributes the Physiograph@ Waverly Press,Inc. graphs. physiological recording systems for use in Waverly Press, Inc., are printers of mag- The company also produces trans- clinical, research, and teaching applica- azines and journals for the association mar- ducers, biotelemetry, signal processors, tions. A selection of multichannel chart ketplace. stimulators, and auditory and animal be- recorders are available with a complete Committed to servicing their customers havior test equipment. line of modular input preamplifiers, signal through sharing knowledge, providing the Major markets include pharmaceutical, conditioners, transducers, and accessories. best in modern technology, and establish- chemical, and biotechnological firms, uni- This allows maximum flexibility to design ing mutual respect, they offer full-range versities, research hospitals, and govern- your own system for recording physiolog- publishing services including design, edi- ment laboratories. ical functions. (Continued on p. 204)

Vol. 29, No. 5, 1986 203 KNOW YOURStJ!TAlNtNG ASOCtAl’S (Continued/romp. 203) torial, composition, printing, binding, As it enters its second century, the Amer- pose of the APS Program Endowment Fund mailing, warehousing, subscription fulfill- ican Physiological Society is in the process is to raise sufficient resources from corpo- ment, and ad sales. of raising an endowment fund for scientific rate and industrial sources, with matching Waverly practices team-concept man- program development designed to foster funds from APS, to stabilize the Society’s agement. Both client and staff are part of vigorous and varied interactions between program activities and limit the need for the team. Through this management con research scientists in the industrial sphere numerous yearly requests to the same cor- cept each publication receives close per- and those in academic institutions. Since porations to fund multiple symposia. sonal attention. 1887, when the Society was founded, APS To convince corporations that their con- Striving for excellence in the graphic has been devoted to fostering basic and tribution to the endowment fund would arts industry is traditional at Waverly-one applied scientific research, to education, eliminate multiple requests for symposia that continues. They believe in quality and to the dissemination of scientific in- support, the Society has guaranteed com- product and service through quality peo- formation. For APS to continue these ac- panies making a significant contribution ple. 98 tivities into its second century, Norman that no further requests would be author- Marshall, Chairman of the Liaison with ln- ized by APS. This has been accomplished dustry Committee, developed the concept by requesting that all symposia organizers of the endowment fund. After extensive work directly with the Executive Secretary discussion, the Society recruited,a steei- Treasurer to coordinate fund-raising activ- ing committee consisting of Theodore ities. Cooper, Philip Felig, Robert Furman, The Society is pleased to announce that Charles Sanders, Howard Morgan, Norman the concept of an endowment fund has Marshall, and Martin Frank. The steering been favorably received by a number of committee’s charge has been to raise the corporations. Corporations making signif- first S250,OOof a projected $l,OOO,OOOen- icant contributions to the endowment fund dowment fund. will be identified as Second Century Cor- The endowment fund provides the porate Founders in the box listing APS mechanism for the equitable distribution Sustaining Associates and duly recognized of resources to symposia organizers. Cur- at the Centennial Meeting. To date, the rently, the Society is unable to allocate Society is pleased to thank Hoffman-La sufficient resources to meet the needs of Roche, Inc., Merck and Co., Inc., Schering the program organizers seeking to attract Corporation, Squibb Corporation, and Up prominent and key scientists as partici- john Company for their contributions to pants in their symposia. Thanks to the crea- the Second-Century Corporate Founders tivity of our symposia organizers and the Program Endowment Fund. Their support generosity of corporations, the Society has of the endowment fund will assist the So- been able to develop and program many ciety in its efforts to maintain a vigorous outstanding symposia. However, repeated scientific program during its “second cen- requests to corporations for contributions tury of progress.” is frustrating to all parties. Thus, the pur-

THE PHYSIOLOGIST