LHRH analogues and degarelix for treatment of prostate cancer – sorted by drug

Drug Degarelix Goserelin Leuprorelin Triptorelin

Drug & Dose Degarelix Goserelin Goserelin Leuprorelin Leuprorelin Leuprorelin Leuprorelin Triptorelin Triptorelin Triptorelin Triptorelin 80mg 3.6mg 10.8mg 3.75mg 3.75mg 11.25mg 22.5mg 3mg 3.75mg 11.25mg 22.5mg Administration Monthly 28 days 12 weekly Monthly Monthly 3 monthly 3 monthly 28 days 4 weekly 3 monthly 6 monthly interval Brand Name Firmagon Zoladex Zoladex Lutrate Prostap SR Prostap 3 Lutrate 3 Decapeptyl Gonapeptyl Decapeptyl Decapeptyl LA Depot DCS DCS month SR Depot SR SR 3.75mg Depot Form Powder with Implant in Implant in Powder for Powder plus Powder plus Powder for Powder for Powder for Powder for Powder for a prefilled prefilled prefilled suspension solvent in solvent in suspension suspension suspension suspension suspension syringe syringe syringe with diluent prefilled prefilled with diluent with diluent with vehicle with diluent with diluent containing in syringe syringe syringe syringe (in ampoule) filled (in ampoule) (in solvent. syringe ampoule) Administration Monthly 28 days 12 weekly Monthly Monthly 3 monthly 3 monthly 28 days 4 weekly 3 monthly 6 monthly interval Needle safety No Yes Yes Yes Yes Yes No No No No No device Needle size 25 gauge 16 gauge 14 gauge 20 gauge 23 gauge 23 gauge 20 gauge 20 gauge 21 gauge 20 gauge 20 gauge

Injection route Deep S/C S/C S/C I/M S/C or I/M S/C I/M I/M S/C or I/M I/M I/M

Injection site Abdomen Anterior Anterior Upper outer Arm, thigh Arm, thigh Upper outer Buttock SC (e.g. Gluteal Gluteal abdominal abdominal quadrant of or abdomen or quadrant of abdomen, muscle muscle wall wall buttock abdomen. buttock buttock or thigh) or by deep IM Links to http://www. http://www http://www http://www. http://www. http://www. http://www. http://www. http://www. http://www. http://www. product info medicines.o .medicines .medicines medicines.o medicines.o medicines.o medicines.o medicines.o medicines.o medicines.o medicines.o rg.uk/emc/m .org.uk/em .org.uk/em rg.uk/emc/m rg.uk/emc/m rg.uk/emc/P rg.uk/emc/m rg.uk/emc/P rg.uk/emc/m rg.uk/emc/P rg.uk/emc/P edicine/216 c/PIL.1075 c/medicine edicine/312 edicine/246 IL.24677.lat edicine/312 IL.4296.late edicine/128 IL.13849.lat IL.24161.lat 86 5.latest.pdf /8146 70 73 est.pdf 71 st.pdf 70 est.pdf est.pdf

Cost* £1552 per £847 per £1018 per £767 per £903 per £903 per £767 per £899 per £1062 per £828 per £828 per year year year year year year year year year year year

Full details can be found by searching drug name on www.emc.medicines.org.uk and searching SPC or PIL. Review: December 2018 *Prices correct 19/01/2017