SIM 2016 Pisa, Palazzo Dei Congressi 25 - 28 Settembre 2016
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44°CONGRESSO NAZIONALE DELLA SOCIETÀ ITALIANA DI MICROBIOLOGIA SIM 2016 Pisa, Palazzo dei Congressi 25 - 28 settembre 2016 Abstract Book CONTENTS INVITED LECTURES DEVELOPMENTS ON ANTIMICROBIAL RESISTANCE SPECIAL SESSIONS _______________________________________________ 7 _______________________________________________ 2 ANTIBIOTIC RESISTANCE AND NEW EMERGENT IMMUNOLOGY OF TUBERCULOSIS RESISTANCE MECHANISMS IN GRAM-POSITIVE F. Dieli BACTERIA S. Stefani EXOSOMES AS INTERCELLULAR PATHOGENESIS, IMMUNITY AND COMMUNICATORS INNOVATIVE THERAPEUTIC APPROACHES IN VIRAL INFECTIONS _______________________________________________ 2 EXOSOMES IN THE DIAGNOSIS OF _______________________________________________ 8 TUBERCULOSIS: ROLE OF SERUM MICRORNAS HOST AND VIRAL GENETIC FACTORS AS A IN THE DIFFERENTIAL DIAGNOSIS BETWEEN RESPONSE TO ANTIVIRAL THERAPY ANTI-HCV: ACTIVE AND LATENT TUBERCULOSIS YESTERDAY AND TODAY COMPARED G. Russo, P. Miotto, A. Ambrosi, D. Goletti, L.R. Codecasa, F. Ceccherini-Silberstein D.M. Cirillo _______________________________________________ 3 _______________________________________________ 8 ROLE OF EXTRACELLULAR VESICLES IN FUNGI INTERFERON AND VIRUSES: A DELICATE AS MEDIATORS OF CELLULAR COMMUNICATION BALANCE BETWEEN YIN AND YANG A. Tavanti C. Scagnolari _______________________________________________ 3 _______________________________________________ 9 microRNA AND EXOSOMES IN HUMAN NEW THERAPEUTIC APPROACHES IN HIV-1 PAPILLOMAVIRUS-INDUCED TUMORIGENESIS INFECTION M.V. Chiantore, G. Fiorucci, G. Mangino, M. Iuliano, I. Bon G. Vaccari, R. Accardi, M. Tommasino, S.C. Cabezas, M. Federic, G. Romeo INNOVATION AND SPEED IN _______________________________________________ 4 MICROBIOLOGICAL DIAGNOSIS EXOSOMES AND MICRORNA IN THE INFECTION AMCLI/SIM SESSION OF POLYOMAVIRUSES S. Giannecchini ______________________________________________ 10 MOLECULAR DIAGNOSIS IN EMERGING PARASITIC DISEASES D. Di Cave EMERGING PATHOGENS IN THE GLOBALIZED WORLD ______________________________________________ 10 SOIPA/SIM SESSION ACCELERATE PHENO: THE NOVEL RAPID PHENOTYPIC ANTIBIOTIC SUSCEPTIBILITY TEST T. Di Martino _______________________________________________ 5 CHAGAS DISEASE A. Bartoloni _______________________________________________ 5 PNEUMOCOCCI AND MENINGOCOCCI: THE FISH-BORNE PARASITIC ZOONOSES THE ENDLESS FIGHT BETWEEN 1 S. Mattiucci, A. Colantoni, M. Paoletti , P. Cipriani, VACCINES AND BACTERIA F. Bruschi, G. Nascetti ______________________________________________ 11 _______________________________________________ 6 CHANGES IN PNEUMOCOCCAL DISEASE MONITORING AEDES ALBOPICTUS BY NOVEL NON- EPIDEMIOLOGY IN THE ERA OF CONVENTIONAL APPROACHES: ZANZAMAPP AND GLYCOCONJUGATE VACCINES CITIZEN SCIENCE A. Pantosti B. Caputo, M. Manica, P. Cobre, F. Filipponi, C. Bianchi, A. della Torre II Contents ______________________________________________ 11 MICROBIAL BIOFILMS NEISSERIA MENINGITIDIS: THE CLUSTER IN ______________________________________________ 18 TUSCANY REGION BIOFILM-ASSOCIATED INFECTIONS: RESISTANCE P. Stefanelli TO ANTIBIOTICS AND NEW THERAPEUTIC STRATEGIES G. Batoni MULTIFACETED ASPECTS OF VIRAL ______________________________________________ 19 VARIABILITY PROSTHETIC JOINTS AND BIOFILM RELATED INFECTIONS ______________________________________________ 12 L. Drago VIRUS EVOLUTION AND EPIDEMIOLOGY G. Rezza ______________________________________________ 19 MULTISPECIES MICROBIAL BIOFILMS; ______________________________________________ 13 SYNERGIES AND ANTAGONISMS ETIC MECHANISMS DRIVING VIRAL VARIABILITY C. Vuotto, G. Donelli C.F. Perno ______________________________________________ 13 VIROME: THE NEW PANDORA’S BOX F. Maggi, L. Macera, D. Focosi, G. Antonelli, M. Pistello FUNCTIONAL FOODS, PROBIOTICS AND HEALTH ADVANCES IN BACTERIOPHAGE ______________________________________________ 20 FUNCTIONAL MICROBES FOR FUNCTIONAL RESEARCH FOODS M. Gobbetti ______________________________________________ 14 PROPHAGES IN THE GUT: FOR GOOD OR FOR ______________________________________________ 21 BAD? A PHAGE PERSPECTIVE PROBIOTICS: USE AND ABUSE M.-A. Petit E. Ghelardi ______________________________________________ 14 ______________________________________________ 21 LYTIC BACTERIOPHAGES AGAINST KPC-KP AND THERAPEUTIC ACTIVITY OF A SACCHAROMYCES THEIR EFFICACY IN A PRECLINICAL MODEL CEREVISIAE-BASED PROBIOTIC AND M.M. D’Andrea, P. Marmo, L. Henrici De Angelis, INACTIVATED WHOLE YEAST ON VAGINAL M. Palmieri, N. Ciacci, E. Demattè, E. Vannuccini, P. Lupetti, CANDIDIASIS G. M. Rossolini, M.C. Thaller E. Gabrielli, N. Ballet ______________________________________________ 15 ______________________________________________ 22 PHAGE SpSL1 GENE EXPRESSION DURING LYTIC THE FOOD-HUMAN AXIS: EFFECT OF DIET ON INFECTION IN STREPTOCOCCUS PNEUMONIAE STRUCTURE AND FUNCTION OF THE HUMAN M.R. Oggioni, L. Furi, R. Haigh MICROBIOME F. De Filippis, N. Pellegrini, L. Vannini, A. La Storia, L. Laghi, R. Di Cagno, I. Ferrocino, C. Lazzi, S. Turroni, PAPILLOMAVIRUSES: PATHOGENIC L. Cocolin, P. Brigidi, E. Neviani, M. Gobbetti, D. Ercolini MECHANISMS, ONCOGENESIS AND VACCINES ______________________________________________ 22 ______________________________________________ 16 FUNCTIONAL AND MOLECULAR DIVERSITY OF HPV AND CANCER. VACCINE EFFICACY SOURDOUGH YEASTS A. Venuti M. Agnolucci, M. Palla, C. Cristani, M. Giovannetti ______________________________________________ 16 INNATE IMMUNITY AGAINST HUMAN PAPILLOMAVIRUS INFECTION MICROBIOLOGICAL MANAGEMENT OF C. Borgogna PATIENTS TREATED WITH BIOLOGIC DRUGS ______________________________________________ 17 ______________________________________________ 23 DOES HPV PLAY A ROLE IN THE PATHOGENESIS THE CLINICAL USE OF BIOLOGICAL AGENTS OF BREAST CANCER? P. Migliorini M. Cricca, S. De Carolis, C. Savini, P. Sansone, M. Bonafè ______________________________________________ 17 THE LINK BETWEEN RESEARCH AND INDUSTRY IN VACCINES DEVELOPMENT M. Ercolani 44nd NATIONAL CONGRESS OF THE ITALIAN SOCIETY OF MICROBIOLOGY III ______________________________________________ 24 C 006 _________________________________________ 32 RISK OF VIRAL INFECTIONS IN BIOLOGICAL ANALYSIS IN VITRO OF THE SPECTRUM AND DRUGS TREATED PATIENTS ANTIBIOTIC RESISTANCE OF P. Ferrante, S. Delbue GRAM-NEGATIVE BACTERIA ISOLATED FROM CATS WITH UTI: RESULTS BASED ON A STUDY ______________________________________________ 24 FROM A VETERINARY HOSPITAL IN ITALY DIAGNOSIS OF TUBERCULOSIS IN PATIENTS P. Robino, R. Odore, C. Tramuta, A. Borrelli, A. Malabaila, REQUIRING BIOLOGIC THERAPY C. Crocillà, P. Nebbia G. Delogu C 007 _________________________________________ 33 ______________________________________________ 24 MOLECULAR BASIS OF AZOLE RESISTANCE IN BIOLOGIC THERAPIES AND THE RISK OF FUNGAL CANDIDA ORTHOPSILOSIS INFECTIONS C. Rizzato, L. Lombardi, M. Zoppo, P. Morici, A. Lupetti, M. Mikulska A. Tavanti C 008 _________________________________________ 34 MOLECULAR CHARACTERIZATION OF PLASMID HARBORING MCR-1 GENE CIRCULATING IN ITALY ORAL COMMUNICATIONS T. Giani, V. Di Pilato, A. Cannatelli, A. Antonelli, F. Luzzaro, PATHOGENESIS, IMMUNITY AND G.M. Rossolini INNOVATIVE THERAPEUTIC APPROACHES IN VIRAL INFECTIONS MOBILE GENETIC ELEMENTS C 001 _________________________________________ 28 OXYSTEROLS AS POTENT INHIBITORS OF HUMAN ROTAVIRUS INFECTION: MECHANISM OF ACTION C 009 _________________________________________ 36 AND PUTATIVE TARGET IDENTIFICATION GENETIC CHARACTERIZATION OF BLPU- A. Civra, R. Francese, V. Cagno, G. Poli, D. Lembo LIKE BACTERIOCIN CASSETTE IN ORAL PROBIOTIC 24 SMBC S. SALIVARIUS C 002 _________________________________________ 28 M. Scillato, S. Stefani, M. Santagati GLUTATHIONYLATION OF VIRAL PROTEINS: A NEW MECHANISM FOR INFLUENZA VIRUS C 010 _________________________________________ 36 PATHOGENICITY? A NOVEL METHOD TO SCREEN FOR MACROLIDE P. Checconi, I. Celestino, M. Marazzato, L. Nencioni, A. Palamara EFFLUX PUMP INHIBITION IN STREPTOCOCCUS PYOGENES C 003 _________________________________________ 29 A. Mosca, D. Bencardino, D. Petrelli, L.A. Vitali EPSTEIN-BARR VIRUS INTERLEUKIN-10 EXPRESSION ENHANCES HUMAN WHARTON’S C 011 _________________________________________ 37 JELLY-DERIVED MESENCHYMAL STEM CELLS WHOLE GENOME SEQUENCING FOR RESISTOME, ENGINEERED IMMUNOSUPPRESSIVE PROPERTIES VIRULOME AND CLONAL LINEAGE PROFILING P. Quaranta, D. Focosi, M. Di Iesu, M. Curcio, A. Paolicchi, F. CHARACTERIZATION OF CARBAPENEM- Scatena, M. Pistello, G. Freer RESISTANT KLEBSIELLA PNEUMONIAE STRAINS ISOLATED IN SICILY, 2014-2016 C 004 _________________________________________ 30 T. Fasciana, B. Gentile, C. Calà, S. Fillo, C. Mascarella, A. Anselmo, A. Fortunato, G. Petralito, S.A. Distefano, HERPESVIRUSES AND NK CELLS: CHARACTERIZATION OF KIR2DL2 ANTIVIRAL F. Lista, A. Giammanco ACTIVITY R. Rizzo, D. Bortolotti, V. Gentili, S. Bolzani, A. Rotola, C 012 _________________________________________ 38 D. Di Luca A NEW MOSAIC INTEGRATIVE AND CONJUGATIVE ELEMENT FROM STREPTOCOCCUS AGALACTIAE CARRYING RESISTANCE GENES FOR CHLORAMPHENICOL (CATQ) AND MACROLIDES [MEF(I) AND ERM(TR)] RECENT DEVELOPMENTS ON S. Simoni, E. Morici, A. Brenciani, E. Giovanetti, ANTIMICROBIAL RESISTANCE P.E. Varaldo, M. Mingoia C 005 _________________________________________ 32 C 013 _________________________________________ 39 ANALYSIS OF THE RESISTOME OF THE BACTERIOPHAGES: AN ALTERNATIVE STRATEGY MICROBIOTA CONTAMINATING HOSPITAL FOR BIOFILM CONTROL IN THE POST-ANTIBIOTIC SURFACES: MODULATION BY A SANITIZING ERA? PROBIOTIC-BASED INTERVENTION T. Tkhilaishvili, A. Trampuz, M. Di Luca E. Caselli,