SULT1A3 polyclonal antibody sulfotransferase with thermolabile enzyme activity. Four sulfotransferase are located on the p arm of Catalog Number: PAB1216 16; this and SULT1A4 arose from a segmental duplication. This gene is the most Regulatory Status: For research use only (RUO) centromeric of the four sulfotransferase genes. of this gene overlap with exons of a gene that encodes a Product Description: Rabbit polyclonal antibody raised containing GIY-YIG domains (GIYD1). Multiple against full length recombinant SULT1A3. alternatively spliced variants that encode the same protein have been described. [provided by RefSeq] Immunogen: Recombinant protein corresponding to full length human SULT1A3. References: 1. Structure-function relationships in the stereospecific Host: Rabbit and manganese-dependent 3,4-dihydroxyphenylalanine/tyrosine-sulfating activity of Reactivity: Human human monoamine-form phenol sulfotransferase, Applications: IHC, WB SULT1A3. Pai TG, Oxendine I, Sugahara T, Suiko M, (See our web site product page for detailed applications Sakakibara Y, Liu MC. J Biol Chem. 2003 Jan information) 17;278(3):1525-32. Epub 2002 Nov 6. 2. Manganese stimulation and stereospecificity of the Protocols: See our web site at Dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating http://www.abnova.com/support/protocols.asp or product activity of human monoamine-form phenol page for detailed protocols sulfotransferase. Kinetic studies of the mechanism using wild-type and mutant enzymes. Pai TG, Ohkimoto K, Form: Liquid Sakakibara Y, Suiko M, Sugahara T, Liu MC. J Biol Chem. 2002 Nov 15;277(46):43813-20. Epub 2002 Sep Recommend Usage: Western Blot (1:1800) 12. The optimal working dilution should be determined by 3. Sulfation through the looking glass--recent advances the end user. in sulfotransferase research for the curious. Coughtrie MW. Pharmacogenomics J. 2002;2(5):297-308. Storage Buffer: In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)

Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 6818

Gene Symbol: SULT1A3

Gene Alias: HAST, HAST3, M-PST, MGC117469, ST1A5, STM, SULT1A4, TL-PST

Gene Summary: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The (number and length of exons) is similar among family members. This gene encodes a phenol

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