The Oesophagus Lined with Gastric Mucous Membrane by P
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The Anatomy of the Rectum and Anal Canal
BASIC SCIENCE identify the rectosigmoid junction with confidence at operation. The anatomy of the rectum The rectosigmoid junction usually lies approximately 6 cm below the level of the sacral promontory. Approached from the distal and anal canal end, however, as when performing a rigid or flexible sigmoid- oscopy, the rectosigmoid junction is seen to be 14e18 cm from Vishy Mahadevan the anal verge, and 18 cm is usually taken as the measurement for audit purposes. The rectum in the adult measures 10e14 cm in length. Abstract Diseases of the rectum and anal canal, both benign and malignant, Relationship of the peritoneum to the rectum account for a very large part of colorectal surgical practice in the UK. Unlike the transverse colon and sigmoid colon, the rectum lacks This article emphasizes the surgically-relevant aspects of the anatomy a mesentery (Figure 1). The posterior aspect of the rectum is thus of the rectum and anal canal. entirely free of a peritoneal covering. In this respect the rectum resembles the ascending and descending segments of the colon, Keywords Anal cushions; inferior hypogastric plexus; internal and and all of these segments may be therefore be spoken of as external anal sphincters; lymphatic drainage of rectum and anal canal; retroperitoneal. The precise relationship of the peritoneum to the mesorectum; perineum; rectal blood supply rectum is as follows: the upper third of the rectum is covered by peritoneum on its anterior and lateral surfaces; the middle third of the rectum is covered by peritoneum only on its anterior 1 The rectum is the direct continuation of the sigmoid colon and surface while the lower third of the rectum is below the level of commences in front of the body of the third sacral vertebra. -
Te2, Part Iii
TERMINOLOGIA EMBRYOLOGICA Second Edition International Embryological Terminology FIPAT The Federative International Programme for Anatomical Terminology A programme of the International Federation of Associations of Anatomists (IFAA) TE2, PART III Contents Caput V: Organogenesis Chapter 5: Organogenesis (continued) Systema respiratorium Respiratory system Systema urinarium Urinary system Systemata genitalia Genital systems Coeloma Coelom Glandulae endocrinae Endocrine glands Systema cardiovasculare Cardiovascular system Systema lymphoideum Lymphoid system Bibliographic Reference Citation: FIPAT. Terminologia Embryologica. 2nd ed. FIPAT.library.dal.ca. Federative International Programme for Anatomical Terminology, February 2017 Published pending approval by the General Assembly at the next Congress of IFAA (2019) Creative Commons License: The publication of Terminologia Embryologica is under a Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) license The individual terms in this terminology are within the public domain. Statements about terms being part of this international standard terminology should use the above bibliographic reference to cite this terminology. The unaltered PDF files of this terminology may be freely copied and distributed by users. IFAA member societies are authorized to publish translations of this terminology. Authors of other works that might be considered derivative should write to the Chair of FIPAT for permission to publish a derivative work. Caput V: ORGANOGENESIS Chapter 5: ORGANOGENESIS -
Case Presentation: High-Grade Esophageal Dysplasia Suspicious for Invasive Adenocarcinoma Within the Context of Long-Segment Barrett’S Esophagus
Case Presentation: High-grade esophageal dysplasia suspicious for invasive adenocarcinoma within the context of long-segment Barrett’s esophagus. Abstract: High grade dysplasia with suspicion of invasive adenocarcinoma was found in multiple esophageal biopsy specimens from a relatively young male with history of long-segment Barrett’s esophagus. Barrett’s esophagus is a known precursor lesion to dysplasia and adenocarcinoma, and the risk increases with long-segment involvement. There is a high inter- observer variability between diagnosing metaplasia, regenerative changes and low grade dysplasia. Additionally, the distinction between high grade dysplasia and intramucosal adenocarcinoma can be difficult to diagnose accurately on biopsy specimens that lack adequate preservation of the muscularis mucosa. Introduction: A 47 year old male with history of Barrett’s esophagus presented for routine follow up with an upper gastrointestinal endoscopy. Results of the procedure showed mucosal changes consistent with long-segment Barrett’s esophagus spanning 10 cm in length. Four quadrant biopsies were performed every 1-2 cm of the esophagus. Gross: The esophagus and gastroesophageal junction were examined with white light and narrow band imaging (NBI) from a forward view and retroflexed position. There were esophageal mucosal changes consistent with long-segment Barrett's esophagus. These changes involved the mucosa at the upper extent of the gastric folds (39 cm from the incisors) extending to the Z-line (29 cm from the incisors). Salmon-colored mucosa was present. The maximum longitudinal extent of these esophageal mucosal changes was 10 cm in length. Mucosa was biopsied in 4 quadrants at intervals of 1 cm in the lower third of the esophagus. -
Respiratory System
Respiratory system Department of Histology and Embryology of Jilin university ----Jiang Wenhua 1. General description z the nose, the pharynx, the larynx, the trachea, bronchus, lung zFunction: inspiring oxygen, expiring carbon dioxide The lung synthesises many materials 2.Trachea and bronchi General structure mucosa submucosa adventitia The trachea is a thin-walled tube about 11centimeters long and 2 centimeters in diameter, with a somewhat flattened posterior shape. The wall of the trachea is composed of three layers: mucosa, submucosa, and adventitia 2.1 mucosa 2.1.1 pseudostratified ciliated columnar epithelium 2.1.1.1 ciliated columnar cells These cells are columnar in shape with a centrally –located oval –shaped nucleus, on the free surface of the cells are microvilli and cilia, which regularly sweep toward the pharynx to remove inspired dust particles 2.1.1.2 brush cells These cells are columnar in shape with a round or oval –shaped nucleus located in the basal portion. on the free surface the microvilli are arranged into the shape of a brush. These cells are considered to be a type of under-developed ciliated columnar cell Schematic drawing of the trachea mucosa Scanning electron micrographs of the surface of mucosa Schematic drawing of the trachea mucosa 2.1.1.3 goblet cells secrete mucus to lubricate and protect the epithelium Schematic drawing of the trachea mucosa 2.1.1.4 basal cells These cells are cone –shaped and situated in the deep layer of the epithelium. Their apices are not exposed to the lumen, and their nuclei are round in shape, such cells constitute a variety of undifferentiated cells 2.1.1.5 small granular cells These cells are a kind of endocrine cells . -
48 Anal Canal
Anal Canal The rectum is a relatively straight continuation of the colon about 12 cm in length. Three internal transverse rectal valves (of Houston) occur in the distal rectum. Infoldings of the submucosa and the inner circular layer of the muscularis externa form these permanent sickle- shaped structures. The valves function in the separation of flatus from the developing fecal mass. The mucosa of the first part of the rectum is similar to that of the colon except that the intestinal glands are slightly longer and the lining epithelium is composed primarily of goblet cells. The distal 2 to 3 cm of the rectum forms the anal canal, which ends at the anus. Immediately proximal to the pectinate line, the intestinal glands become shorter and then disappear. At the pectinate line, the simple columnar intestinal epithelium makes an abrupt transition to noncornified stratified squamous epithelium. After a short transition, the noncornified stratified squamous epithelium becomes continuous with the keratinized stratified squamous epithelium of the skin at the level of the external anal sphincter. Beneath the epithelium of this region are simple tubular apocrine sweat glands, the circumanal glands. Proximal to the pectinate line, the mucosa of the anal canal forms large longitudinal folds called rectal columns (of Morgagni). The distal ends of the rectal columns are united by transverse mucosal folds, the anal valves. The recess above each valve forms a small anal sinus. It is at the level of the anal valves that the muscularis mucosae becomes discontinuous and then disappears. The submucosa of the anal canal contains numerous veins that form a large hemorrhoidal plexus. -
Regeneration of the Mucosal Lining of the Esophagus
Henry Ford Hospital Medical Journal Volume 11 | Number 2 Article 2 6-1963 Regeneration Of The ucoM sal Lining Of The Esophagus Jean van de Kerckhof Thomas Gahagan Follow this and additional works at: https://scholarlycommons.henryford.com/hfhmedjournal Part of the Life Sciences Commons, Medical Specialties Commons, and the Public Health Commons Recommended Citation van de Kerckhof, Jean and Gahagan, Thomas (1963) "Regeneration Of The ucM osal Lining Of The Esophagus," Henry Ford Hospital Medical Bulletin : Vol. 11 : No. 2 , 129-134. Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol11/iss2/2 This Article is brought to you for free and open access by Henry Ford Health System Scholarly Commons. It has been accepted for inclusion in Henry Ford Hospital Medical Journal by an authorized editor of Henry Ford Health System Scholarly Commons. For more information, please contact [email protected]. Henry Ford Hosp. Med. Bull. Vol. 11, June, 1963 REGENERATION OF THE MUCOSAL LINING OF THE ESOPHAGUS JEAN VAN DE KERCKHOF, M.D.,* AND THOMAS GAHAGAN, M.D.* IN THE HUMAN embryo the esophagus is initially lined with stratified columnar epithelium which later becomes ciliated. The columnar epithelium is replaced by squamous epithelium in process which begins in the middle third of the esophagus and spreads proximally and distally to cover the entire esophageal lumen.' The presence of columnar epithelium in an adult esophagus is an unusual finding. In all of the clinical cases with which we are familiar, it has been associated with hiatus hernia, reflux esophagitis and stricture formation, as in the cases described by Allison and Johnstone^. -
Head and Neck
DEFINITION OF ANATOMIC SITES WITHIN THE HEAD AND NECK adapted from the Summary Staging Guide 1977 published by the SEER Program, and the AJCC Cancer Staging Manual Fifth Edition published by the American Joint Committee on Cancer Staging. Note: Not all sites in the lip, oral cavity, pharynx and salivary glands are listed below. All sites to which a Summary Stage scheme applies are listed at the begining of the scheme. ORAL CAVITY AND ORAL PHARYNX (in ICD-O-3 sequence) The oral cavity extends from the skin-vermilion junction of the lips to the junction of the hard and soft palate above and to the line of circumvallate papillae below. The oral pharynx (oropharynx) is that portion of the continuity of the pharynx extending from the plane of the inferior surface of the soft palate to the plane of the superior surface of the hyoid bone (or floor of the vallecula) and includes the base of tongue, inferior surface of the soft palate and the uvula, the anterior and posterior tonsillar pillars, the glossotonsillar sulci, the pharyngeal tonsils, and the lateral and posterior walls. The oral cavity and oral pharynx are divided into the following specific areas: LIPS (C00._; vermilion surface, mucosal lip, labial mucosa) upper and lower, form the upper and lower anterior wall of the oral cavity. They consist of an exposed surface of modified epider- mis beginning at the junction of the vermilion border with the skin and including only the vermilion surface or that portion of the lip that comes into contact with the opposing lip. -
Human Anatomy and Physiology
LECTURE NOTES For Nursing Students Human Anatomy and Physiology Nega Assefa Alemaya University Yosief Tsige Jimma University In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education 2003 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2003 by Nega Assefa and Yosief Tsige All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty in a health care field. Human Anatomy and Physiology Preface There is a shortage in Ethiopia of teaching / learning material in the area of anatomy and physicalogy for nurses. The Carter Center EPHTI appreciating the problem and promoted the development of this lecture note that could help both the teachers and students. -
Nomina Histologica Veterinaria, First Edition
NOMINA HISTOLOGICA VETERINARIA Submitted by the International Committee on Veterinary Histological Nomenclature (ICVHN) to the World Association of Veterinary Anatomists Published on the website of the World Association of Veterinary Anatomists www.wava-amav.org 2017 CONTENTS Introduction i Principles of term construction in N.H.V. iii Cytologia – Cytology 1 Textus epithelialis – Epithelial tissue 10 Textus connectivus – Connective tissue 13 Sanguis et Lympha – Blood and Lymph 17 Textus muscularis – Muscle tissue 19 Textus nervosus – Nerve tissue 20 Splanchnologia – Viscera 23 Systema digestorium – Digestive system 24 Systema respiratorium – Respiratory system 32 Systema urinarium – Urinary system 35 Organa genitalia masculina – Male genital system 38 Organa genitalia feminina – Female genital system 42 Systema endocrinum – Endocrine system 45 Systema cardiovasculare et lymphaticum [Angiologia] – Cardiovascular and lymphatic system 47 Systema nervosum – Nervous system 52 Receptores sensorii et Organa sensuum – Sensory receptors and Sense organs 58 Integumentum – Integument 64 INTRODUCTION The preparations leading to the publication of the present first edition of the Nomina Histologica Veterinaria has a long history spanning more than 50 years. Under the auspices of the World Association of Veterinary Anatomists (W.A.V.A.), the International Committee on Veterinary Anatomical Nomenclature (I.C.V.A.N.) appointed in Giessen, 1965, a Subcommittee on Histology and Embryology which started a working relation with the Subcommittee on Histology of the former International Anatomical Nomenclature Committee. In Mexico City, 1971, this Subcommittee presented a document entitled Nomina Histologica Veterinaria: A Working Draft as a basis for the continued work of the newly-appointed Subcommittee on Histological Nomenclature. This resulted in the editing of the Nomina Histologica Veterinaria: A Working Draft II (Toulouse, 1974), followed by preparations for publication of a Nomina Histologica Veterinaria. -
1 the Anatomy and Physiology of the Oesophagus
111 2 3 1 4 5 6 The Anatomy and Physiology of 7 8 the Oesophagus 9 1011 Peter J. Lamb and S. Michael Griffin 1 2 3 4 5 6 7 8 911 2011 location deep within the thorax and abdomen, 1 Aims a close anatomical relationship to major struc- 2 tures throughout its course and a marginal 3 ● To develop an understanding of the blood supply, the surgical exposure, resection 4 surgical anatomy of the oesophagus. and reconstruction of the oesophagus are 5 ● To establish the normal physiology and complex. Despite advances in perioperative 6 control of swallowing. care, oesophagectomy is still associated with the 7 highest mortality of any routinely performed ● To determine the structure and function 8 elective surgical procedure [1]. of the antireflux barrier. 9 In order to understand the pathophysiol- 3011 ● To evaluate the effect of surgery on the ogy of oesophageal disease and the rationale 1 function of the oesophagus. for its medical and surgical management a 2 basic knowledge of oesophageal anatomy and 3 physiology is essential. The embryological 4 Introduction development of the oesophagus, its anatomical 5 structure and relationships, the physiology of 6 The oesophagus is a muscular tube connecting its major functions and the effect that surgery 7 the pharynx to the stomach and measuring has on them will all be considered in this 8 25–30 cm in the adult. Its primary function is as chapter. 9 a conduit for the passage of swallowed food and 4011 fluid, which it propels by antegrade peristaltic 1 contraction. It also serves to prevent the reflux Embryology 2 of gastric contents whilst allowing regurgita- 3 tion, vomiting and belching to take place. -
Gastric and Duodenal Mucosa in 'Healthy' Individuals an Endoscopic and Histopathological Study of 50 Volunteers
J Clin Pathol: first published as 10.1136/jcp.31.1.69 on 1 January 1978. Downloaded from Journal of Clinical Pathology, 1978, 31, 69-77 Gastric and duodenal mucosa in 'healthy' individuals An endoscopic and histopathological study of 50 volunteers J. KREUNING1, F. T. BOSMAN2, G. KUIPER', A. M. v.d. WAL2, AND J. LINDEMAN2 From the Department of Gastroenterology' and the Department ofPathology2, University Medical Centre, Wassenaarseweg 62, Leiden, The Netherlands SUMMARY The results of histological and immunohistochemical examination of gastric and duo- denal biopsy specimens from 50 volunteers without a clinical history of gastrointestinal disease are reported. Multiple specimens of tissue from standard sites in the stomach and duodenum were carefully orientated, and serially sectioned for examination by light microscopy and for immuno- histochemical characterisation of plasma cells within the lamina propria. The antrum and fundus were normal in 32 of the 50 subjects but the other 18 showed histo- pathological evidence of gastritis in either the antrum or fundus. The latter appeared to be age- related. There was considerable variation in the appearance of the surface epithelium of the duodenum within as well as among individual subjects. Superficial gastric metaplasia in one or more biopsy copyright. specimens from the duodenal bulb was found in 64% of individuals. Histopathological examina- tion of the duodenum revealed signs of chronic inflammation in 12 % ofthe subjects. In two individ- uals there was active inflammation but in only one of these was the diagnosis made on endoscopic appearances. Histological criteria important for the diagnosis of duodenitis are discussed. The number of plasma cells in different biopsy specimens from subjects not showing histological signs of inflammation was variable. -
Diagnostic Upper Endoscopy Jean Marc Canard, Jean-Christophe Létard, Anne Marie Lennon
CHAPTER 3 Diagnostic upper endoscopy Jean Marc Canard, Jean-Christophe Létard, Anne Marie Lennon Summary Introduction 84 4. Equipment 90 1. Upper gastrointestinal anatomy 84 5. Endoscopy technique 91 2. Indications 85 6. Complications 97 3. Contraindications 90 7. Upper endoscopy in children 99 Key Points the horizontal line that passes through the cardia and that is visible in a retroflexed endoscopic view. The body is the ᭹ Upper endoscopy is a commonly performed procedure. remainder of the upper part of the stomach and is delimited ᭹ Always intubate under direct vision and never push. at its lower edge by the line that passes through the angular ᭹ Be aware of ‘blind’ areas, which can be easily missed. notch. Endoscopically, the transition from the body to the ᭹ Cancers should be classified using the Paris classification system. antrum is seen as a transition from rugae to flat mucosa (Fig. 4). The pylorus is a circular orifice, which leads to the first part of the duodenum. Introduction Esophagogastroduodenoscopy (EGD) is one of the com- monest procedures that a gastroenterologist performs. This chapter covers how to perform a diagnostic upper endos- copy. Therapeutic interventions in upper endoscopy are dis- Dental arch cussed in Chapter 7. 1. Upper gastrointestinal anatomy 15 cm 1.1. The esophagus C6 The cervical segment of the esophagus begins at the upper esophageal sphincter, which is 15 cm from the incisors and 40 cm 1/3 proximal is 6 mm long (Fig. 1). The thoracic segment of the esophagus esophagus is approximately 19 cm long. Its lumen is open during inspi- D4 ration and closed during expiration.