INSTITUTE OF HEMATOLOGY AND ONCOLOGY “L. AND A. SERÀGNOLI” It’s time to take care of T-Cell Lymphomas

Presidents: Michele Baccarani Stefano Pileri Pier Luigi Zinzani

Honorary President: Sante Tura

Bologna, ROYAL HOTEL CARLTON October 22-24, 2006 PROGRAM It’s time to Faculty: Sergio Amadori Roma, take care of Agustin Aviles Mexico City, Mexico Alma Mater Studiorum Presidents: Michele Baccarani Bologna, Italy Università di Bologna T-Cell Susan Bates Bethesda, USA Michele Baccarani Emilio Berti Monza, Italy Lymphomas Stefano Pileri Bruce Cheson Washington, USA Pier Luigi Zinzani Teodoro Chisesi Venezia, Italy Bologna, Paolo Corradini Milano, Italy Romano Danesi Pisa, Italy ROYAL HOTEL CARLTON Francesco D’Amore Arhus, October 22-24, 2006 Honorary President: Fabrizio De Ponti Bologna, Italy Sante Tura Reinhard Dummer Zurich, Madeleine Duvic Houston, USA Brunangelo Falini Perugia, Italy Auspices Francine Foss New Haven, USA Richard Furman New York, USA MINISTERO DELLA SALUTE Gianluca Gaidano Novara, Italy Varsha Gandhi Houston, USA SIE Scientific Committee UNIVERSITÀ DEGLI STUDI DI BOLOGNA Philippe Gaulard Creteil, Christian Gisselbrecht Paris, France Sergio Amadori REGIONE EMILIA ROMAGNA Steven Horwitz New York, USA Elaine Jaffe Bethesda, USA President ASSOCIAZIONE ITALIANA CONTRO LE John Janik Bethesda, USA LEUCEMIE - LINFOMI E MIELOMA Michael J. Keating Houston, USA Emanuele Angelucci Mario Lazzarino Pavia, Italy Paolo Corradini SEZIONE DI BOLOGNA Raymond Liang Hong Kong - China Mario Lazzarino Ying-Wei Lin Nara, Japan Maurizio Martelli Roma, Italy Francesco Lo Coco Enrica Morra Milano, Italy Gina Zini Owen O’Connor New York, USA Pier Luigi Zinzani Francesco Onida Milano, Italy Fabrizio Pane Napoli, Italy Marco Paulli Pavia, Italy Stefano Pileri Bologna, Italy Nicola Pimpinelli Firenze, Italy Scientific Secretariat William Plunkett Houston, USA Pierluigi Porcu Columbus, USA Monica Tani, Elena Sabattini Stephen John Proctor Newcastle, UK Istituto di Ematologia ed Oncologia Medica Peter Reimer Wurzburg, “L. e A. Seràgnoli” - Via Massarenti, 9 Damiano Rondelli Chicago, USA Steven Rosen Chicago, USA 40138 Bologna, Italy Thomas Ruediger Wurzburg, Germany Tel. +39 051 6363680 - Fax +39 051 6364037 Marco Santucci Firenze, Italy Monica Tani Bologna, Italy Corrado Tarella Torino, Italy Kensei Tobinai Tokyo, Japan Organizing Secretariat Giuseppe Torelli Modena, Italy Studio E.R. Congressi - Gruppo Triumph Lorraine Tracey Memphis, USA Via Marconi, 36 - 40122 Bologna, Italy Umberto Vitolo Torino, Italy Julie M. Vose Omaha, USA Tel. +39 051 4210559 - Fax +39 051 4210174 Dennis D. Weisenburger Omaha, USA e-mail: [email protected] Sean Whittaker London, UK www.ercongressi.it Rein Willemze Leiden, The Uwe Wollina Dresden, Germany Pier Luigi Zinzani Bologna, Italy 4 5 October 22, 2006

2.30 p.m. Welcome and Introduction

2.45 p.m. State of the Art on T-cell lymphomas: Chairmen: S. Amadori, G. Torelli Epidemiology R. Liang Pathogenesis E. Jaffe Conventional treatment of PTCL: the European perspective - C. Gisselbrecht the US perspective - J. Vose the Asian perspective - K. Tobinai the Caribbean perspective - A. Aviles Conventional treatment of CTCL S.Whittaker

5.45 p.m. PTCL: Morphology and Biology Chairmen: G. Gaidano, F. Pane It’s time to Histology P. Gaulard take care of Molecular Biology T-Cell T. Ruediger Gene Expression Profiling Lymphomas S. Pileri It’s time to October 23, 2006 6 7 take care of T-Cell Lymphomas

8.30 a.m. PTCL: Innovative Treatments CTLA4 receptor J.E. Janik Histone deacetylase inhibitors Chairmen: O.A. O'Connor, U. Vitolo Clofarabine S. Horwitz HDACI and SAHA phase I-II data O.A. O'Connor Linalidomide S. Rosen Depsipeptide S. Bates Nelarabine M.J. Keating MS-275 P. Porcu Other “new new” drugs B. Cheson

10.00 a.m. Coffee Break 1.30 p.m. Lunch

10.15 a.m. Monoclonoal antibodies and others Chairmen: M. Martelli, E. Morra 2.30 p.m. CTCL: Morphology and Biology Chairmen: B. Falini, M. Paulli Campath-1H F. D'Amore Histology M. Santucci Anti-CD30 S.J. Proctor Molecular Biology E. Berti BCX-1777 (Forodesine): preclinical data - V. Gandhi Gene Expression Profiling clinical data - R. Furman L. Tracey Praletrexate O.A. O'Connor 3.45 p.m. Coffee Break It’s time to take care of 8 9 October 24, 2006 T-Cell Lymphomas

4.00 p.m. CTCL: Innovative Treatments 8.30 a.m. From Mouse Models to Prognostic Factors Chairmen: M. Lazzarino, U. Vitolo Chairmen: R. Danesi, F. De Ponti Campath-1H LECTURE: “Animals models of T-cell lymphomas” S. Rosen Ying-Wei Lin HuMax-CD4 F. D'Amore LECTURE: “Why the same drugs are active in Ontak B-cell and not in T-cell lymphomas?” M. Duvic W. Plunkett Gemcitabine Prognostic Factors: M. Tani Pegylated Liposomal Doxorubicin PTCL U. Wollina D.D. Weisenburger Interferon CTCL R. Dummer R. Willemze Bexarotene M. Duvic When and which aggressive treatment? Chairmen: D. Rondelli, C. Tarella Bortezomib P.L. Zinzani Chemotherapy in PTCL Other “new new” drugs J. Vose F. Foss Chemotherapy in CTCL N. Pimpinelli It’s time to take care of 10 T-Cell Lymphomas

Autotransplant in PTCL P. Reimer Allotransplant in PTCL P. Corradini Auto and Allotransplant in CTCL F. Onida

Bologna, ROYAL HOTEL CARLTON October 22-24, 2006

It’s time to take care of T-Cell Lymphomas It’s time to take care of 12 13 GENERAL INFORMATION TRAVEL AGENCY Meeting venue T-Cell Bononia Viaggi ROYAL HOTEL CARLTON Lymphomas Piazza Martiri, 1 - 40122 Bologna Italy Via Montebello, 8 - 40121 Bologna, Italy Phone +39 - 051 4211585 Phone +39 051 249361 - Fax +39 051 249724 Fax +39 - 051 249846 [email protected]

HOW TO GET THERE HOTEL RESERVATION By car From the motorway, turn into the ring road ("Tangenziale") - Exit 7 “Fiera” and Category Double Single Use Double follow direction city center and railway station. MIN. MAX. MIN. MAX. By taxi From the airport about 30 minutes. 4 STARS Euro 125,00 Euro 185,00 Euro 155,00 Euro 225,00 By bus Bus 91 and Aerobus from the airport. 3 STARS Euro 114,00 Euro 124,00 From the railway station walking distance.

OFFICIAL LANGUAGE Reservation fee, € 20,00 per room. Prices are inclusive of tax service and breakfast, per room per night. Please fill in the hotel reservation form and send it to the official travel agency Bononia Viaggi before September 30th, 2006. English. Hotel reservation can only be accepted and confirmed when the form and the confirmatory deposit (the price of € REGISTRATION FEE one night per room in the selected hotel category plus 20,00 for agency rights) have been received by Bononia Viaggi. Payments must be done in Euro net of all bank charges and made out to Bononia Viaggi S.r.l. Please pay Euro 350,00 by: The registration fee includes: * Eurocheque or Foreign · Conference kit * Bank transfer made out to Bononia Viaggi S.r.l. - Account n° 9000/2 - Cassa di Risparmio di Bologna · Partecipation in the scientific sessions · Proceedings Book Filiale S. Giuseppe, Via Saragozza 87, 40135 Bologna BO Italy - ABI 6385 - CAB 02418 · Attendance Certificate * · Coffee breaks Please send a copy of the bank transfer with the hotel reservation form. In case of written cancellation before · Lunch September 30th, 2006, 80% of the fee will be refunded. REGISTRATION: Registrations can only be accepted and confirmed after the registration form and fee have been received by the Organizing Secretariat, Studio E.R. Congressi. All payments must be done in Euro net of all bank charges and made out to Studio E.R. Congressi S.r.l. Please pay by:

* Eurocheque or Foreign Cheque * Bank transfer made out to Studio E.R. Congressi S.r.l. CASSA DI RISPARMIO DI CESENA - Agenzia n° 29, Largo Caduti del Lavoro 1/A, Bologna I Swift code: CECRIT 2C - Iban code: IT 36J 0612002400246000000002596 - ABI 06120 - CAB 02400 Account n° 000000002596 * Credit Card Please send a copy of the bank transfer with the registration form. In case of written cancellation before August 31st, 2006, 80% of the registration fee will be refunded. It’s time to It’s time to take care of 14 take care of SCIENTIFIC INFORMATION REGISTRATION FORM T-Cell Please, return this form to: T-Cell Lymphomas Studio E.R. Congressi - Via Marconi 36 Lymphomas 40122 Bologna BO Italy Phone +39-051 4210559 Bologna, Fax +39-051 4210174 ROYAL HOTEL CARLTON [email protected] October 22-24, 2006 Slides Slides must be in English. Computer videoprojection will be available in Power Point. LAST NAME Other requirements should be communicated to the Organizing Secretariat as soon as possible. Slides should be handed to the slide center one hour before the beginning of the session and collected at the end. FIRST NAME

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