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Kurt Michael Fraser, Phd 142 Weill Hall Cell: #3200, Berkeley, CA 94720 Email: Kurt.Fraser@Berkeley.Edu Updated May 2021 Kurt Michael Fraser, PhD 142 Weill Hall Cell: #3200, Berkeley, CA 94720 Email: [email protected] CURRENT POSITION Postdoctoral Scholar May 2021-Present University of California - Berkeley Supervisor: Stephan Lammel, PhD EDUCATION Johns Hopkins University, Baltimore, MD 2021 PhD in Psychological & Brain Sciences (Biopsychology) Supervisor: Patricia H. Janak, PhD Dissertation Topic: Setting the Occasion for Reward-seeking in Brain and Behavior Johns Hopkins University, Baltimore, MD 2017 MA in Psychological & Brain Sciences (Biopsychology) Supervisor: Patricia H. Janak, PhD Master’s Thesis: Dorsal and Ventral Striatal Systems in the Attribution of Incentive Salience to Reward-Paired Cues University of Michigan, Ann Arbor, MI 2015 BS in Neuroscience with High Honors & Distinction Supervisor: Shelly B. Flagel, PhD Thesis: Contributions of Dopamine D2 and D3 Receptors to Pavlovian Conditioned Approach RESEARCH INTERESTS Neurobiological mechanisms of cue-triggered motivated behavior: • How are reward learning and conditioned motivation separable in both behavior and neurobiology? • What neural circuits underlie the attribution of conditioned motivation to reward-paired cues? • How is ambiguity about the motivational value of conditioned cues in the environment resolved to produce reward-seeking? • What is the content of learning? • How do neural circuits supporting adaptive reward-seeking go awry in mental health disorders such as alcohol abuse and addiction? RESEARCH SUPPORT AND FELLOWSHIPS NIH BRAIN Initiative Fellows NRSA Postdoctoral Fellowship (F32 MH127792) 2021-2024 Using large-scale electrophysiology to study the role of midbrain dopamine neurons underlying motivated behavior NIH NRSA Predoctoral Fellowship (F31 DA046136) 2019-2021 The role of the basolateral amygdala in occasion setting Kurt M. Fraser Curriculum Vitae Updated May 2021 MANUSCRIPTS IN PREPARATION Fraser KM, Collins V, Pat F, Saunders BT, & Janak PH. Hierarchical control of mesolimbic dopamine and striatal encoding of reward-paired cues governs flexible behavioral responding. Fraser KM, Kim TH, Padovan-Hernandez Y, Chen B, Pat F, Ottenheimer DJ, & Janak PH. Encoding of consumption and enhancement of reward and drug preference by the central nucleus of the amygdala. Fraser KM & Janak PH. Amygdalocortical circuits underlying flexible cue-triggered motivation. Fraser KM & Janak PH. Hierarchical regulation of reward-seeking, reinforcement, and relapse. PUBLICATIONS Ottenheimer DJ, Wang K, Tong X, Fraser KM, Richard JM, & Janak PH. (2020). Reward activity in ventral pallidum tracks satiety-sensitive preference and drives choice behavior. Science Advances. 6(45). doi: 10.1126/sciadv.abc9321 Ottenheimer DJ, Bari BA, Sutlief E, Fraser KM, Kim TH, Richard JM, Cohen JY & Janak PH. (2020). A quantitative reward prediction error signal in the ventral pallidum. Nature Neuroscience. 23(10): 1267- 1276. doi: 10.1038/s41593-020-0688-5 *Originally a preprint on bioRxiv Fraser KM & Janak PH. (2019). Occasion setters attain incentive motivational value: implications for contextual influences on reward-seeking. Learning & Memory. 26:291-298. doi: 10.1101/lm.049320.119 *Originally a preprint on bioRxiv Fraser KM & Janak PH. (2019). How does drug use shift the balance between model-based and model-free control of decision-making? Biological Psychiatry. 85(11): 886-888. doi: 10.1016/j.biopsych.2019.04.106 *Commentary on Groman et al. 2019 Fraser KM & Holland PC. (2019). Occasion Setting. Behavioral Neuroscience. 133(2):145-175. doi: 10.1037/bne0000306 Fraser KM & Janak PH. (2018). Stressing the other paraventricular nucleus. Nature Neuroscience. 21(7):901-902. doi: 10.1038/s41593-018-0178-1 *News & Views on Beas, Wright et al. 2018 Fraser KM & Janak PH. (2017). Long-lasting contribution of dopamine in the nucleus accumbens core, but not dorsal lateral striatum, to sign-tracking. European Journal of Neuroscience. 46(4):2047-2055. doi: 10.1111/ejn.13642 *Originally a preprint on bioRxiv Haight JL, Fuller ZL, Fraser KM & Flagel SB. (2017). A food-predictive cue attributed with incentive salience engages subcortical afferents and efferents of the paraventricular nucleus of the thalamus. Neuroscience. 340:135-152. doi: 10.1016/j.neuroscience.2016.10.043 Kurt M. Fraser Curriculum Vitae Updated May 2021 Fraser KM & Haight JL. (2016). Diminished Dopamine: Timing, Neuroanatomy, or Drug History? The Journal of Neuroscience. 36(18):4907-4909. doi: 10.1523/JNEUROSCI.0731-16.2016 * Journal Club review of Saddoris et al. 2016 Fraser KM, Haight JL, Gardner EL & Flagel SB. (2016). Examining the role of dopamine D2 and D3 receptors in Pavlovian conditioned approach behaviors. Behavioural Brain Research. 305:87-99. doi: 10.1016/j.bbr.2016.02.022 Haight JL, Fraser KM, Akil H & Flagel SB. (2015). Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses. European Journal of Neuroscience. 42(7):2478-2488. doi: 10.1111/ejn.13031 HONORS AND AWARDS Robert S. Waldrop Award for Outstanding Scholarship & Leadership, Johns Hopkins University 2021 Enoch Gordis Award Finalist, Research Society on Alcoholism 2020 Outstanding Poster Award, Winter Conference on Brain Research 2019 Travel Award, Winter Conference on Brain Research 2019 Trainee Professional Development Award, Society for Neuroscience 2018 Robert S. Waldrop Junior Investigator Award, Johns Hopkins University 2018 Special Opportunities for Undergraduate Learning Course Award, Johns Hopkins University 2017 Collaborative Research Award, Psychological & Brain Sciences, Johns Hopkins University 2017 Walter L. Clark Service Award, Psychological & Brain Sciences, Johns Hopkins University 2017 Honorable Mention, National Science Foundation Graduate Research Fellowship Program 2017 Owen Scholars Award, Johns Hopkins University 2015-2018 Graduated with Distinction, University of Michigan 2015 University of Michigan Wilson P. “Spike” Tanner Memorial Award 2014 Faculty for Undergraduate Neuroscience Travel Award 2014 University of Michigan Literature, Science, and Arts Internship Scholarship 2014 Michigan Schools and Government Credit Union Scholarship 2011 Michigan Education Association Scholarship 2011 National Multiple Sclerosis Society Scholarship 2011 TEACHING EXPERIENCE Johns Hopkins University: Guest Lecture, AS.200.335 How Does the Brain Predict the Future? 2019 • “Reward Prediction Error-based Learning” Guest Lecture, AS.200.369 Neuroscience of Motivation and Reward 2019 • “Social Reward” Teaching Assistant, AS.200.369 Neuroscience of Motivation and Reward 2018 • Responsible for grading, developing assessments and exams, private tutoring Instructor, AS.360.111, Setting up for Success in Systems Neuroscience 2017 • Independently developed and taught 6-week course designed for underclassmen Teaching Assistant, AS.200.368 Sleep, Dreams, and Altered States of Consciousness 2017 • Responsible for grading, private tutoring, developing course materials, overseeing IRB approval for independent research projects • Lectures Given: “Statistics for Psychological Sciences” & “Sleep and Memory: A Neural Perspective” Teaching Assistant, AS.200.314 Advanced Statistical Methods 2016 Kurt M. Fraser Curriculum Vitae Updated May 2021 • Responsible for developing exams and homework, grading, private tutoring Guest Lecture, AS.200.303 Psychobiology of Addiction 2016 • “Individual differences in the attribution of incentive salience: implications for addiction” Teaching Assistant, AS.200.369 Neuroscience of Motivation and Reward 2016 • Responsible for grading, developing assessments and exams, private tutoring • Lectures Given: “Introduction to Addiction Theory: Opponent Process and Habits” & “Introduction to Addiction Theory: Incentive Sensitization” Laboratory mentor to 6 undergraduate research assistants 2016-2021 Department of Neuroscience, Icahn School of Medicine at Mount Sinai 2020, 2021 Guest Lecture, BSR 1707 Behavioral and Cognitive Neuroscience • “Incentive Salience, Wanting, and Liking” University of Michigan Science Learning Center Study Group Leader, Biology 225 Introduction to Animal Physiology and Neurobiology 2014 Study Group Leader, Chemistry 210 Structure and Reactivity I 2013-2014 SERVICE Johns Hopkins University Chair, Climate Committee Working Group, Department of Psychological & Brain Sciences 2020-2021 Co-Chair, School Outreach Committee, Department of Psychological & Brain Sciences 2018 Chair, Colloquium Committee, Department of Psychological & Brain Sciences 2016-2017 Student Chair, PhD Admissions Committee, Department of Psychological & Brain Sciences 2016-2017 University of Michigan Vice President, University of Michigan Neuroscience Student Association 2017 VOLUNTEERING AND OUTREACH Coordinator, Baltimore Brain Series 2016-2019 Editor, Interstellate Magazine 2016-2017 (http://interstellate.me/ & https://twitter.com/interstellate_/) Contributor for PLoS Neurocommunity Society for Neuroscience 2016 Coverage 2016 (http://blogs.plos.org/neuro/2016/10/24/meet-the-plos-sfn16-contributors/) Brain Awareness Day, Baltimore Polytechnic Institute, Baltimore, MD 2016-2017 Brains Rule! Neuroscience Youth Outreach, University of Michigan, Ann Arbor, MI 2014-2015 Student Volunteer, University of Michigan Cardiovascular Center, Ann Arbor, MI 2013-2014 Peer Mentor, University of Michigan Office of New Student Programs 2012-2015 PROFESSIONAL MEMBERSHIPS Research Society on Alcoholism (2019-present), Associate Faculty Member F1000 (2018-present), Pavlovian Society (2017-present),
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