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Secondary Endolymphatic Hydrops SECONDARY ENDOLYMPHATIC HYDROPS By Susan Pesznecker, RN, with the Vestibular Disorders Association. Updates by Jeremy Hinton, DPT. Endolymphatic hydrops is a disorder of the inner SYMPTOMS ear and can affect the endolymphatic fluid of the Symptoms typical of hydrops include pressure or cochlea, the vestibular apparatus, or both. fullness in the ears (aural fullness), tinnitus (ringing Although its underlying cause and natural history or other noise in the ears), hearing loss, dizziness, are unknown, it is believed to result from and imbalance. abnormalities in the quantity, composition, and/or pressure of the endolymph (the fluid within the DIAGNOSIS AND TESTING endolymphatic sac, a compartment of the inner Diagnosis is often clinical—based on the physician’s ear). observations and on the patient’s history, symptoms, and symptom pattern. The clinical In a normal inner ear, the endolymph is maintained diagnosis may be strengthened by the results of at a constant volume and with specific certain tests. For example, certain abnormalities in concentrations of sodium, potassium, chloride, and electrocochleography (which tests the response of other electrolytes. This fluid bathes the sensory the eighth cranial nerve to clicks or tones cells of the inner ear and allows them to function presented to the ear) or audiometry (which tests normally. In an inner ear affected by hydrops, hearing function) may support a hydrops diagnosis. these fluid-system controls are believed to be lost New research has shown that MRI with contrast in or damaged. This may cause the volume and the inner ear can give a definitive diagnosis of concentration of the endolymph to fluctuate in endolymphatic hydrops, but likely would not be response to changes in the body’s circulatory fluids able to differentiate between primary (Meniere’s) and electrolytes. and secondary. This is most commonly not used because clinical diagnosis is often accurate. CAUSES Endolymphatic hydrops may be either primary or TREATMENT GOALS secondary. Primary idiopathic endolymphatic Ménière’s disease (primary idiopathic endolym- hydrops (known as Ménière’s disease) occurs for phatic hydrops) is discussed in detail in a separate no known reason. Secondary endolymphatic publication of the Vestibular Disorders Association hydrops appears to occur in response to an event (see the list at the end of this document). In brief, or underlying condition. For example, it can follow Ménière’s disease is characterized by sudden, head trauma or ear surgery, and it can occur with violent attacks or episodes of vertigo, tinnitus, other inner ear disorders, allergies, or systemic hearing loss, and aural fullness. The attacks disorders (such as diabetes or autoimmune typically occur at intervals of weeks to months, disorders). with symptom-free periods between attacks. Over several years, there is partial destruction of hearing and sometimes of balance function. VESTIBULAR DISORDERS ASSOCIATION 5018 NE 15th Ave, Portland, OR 97211 (800) 837-8428 vestibular.org TAX-ID#93-0194340 Ménière’s disease affects both ears in up to half of electrolyte levels remain stable. those who experience it. Treatment is intended to improve symptoms, manage acute attacks, deal A second key element of the HDR is minimizing the with the damage to hearing and balance, and use of solutes (salts and sugars) in the diet. Solutes maintain quality of life. require the body to use large amounts of fluid for dilution and digestion. This causes large The treatment of secondary endolymphatic fluctuations in body fluids and consequently in the hydrops (SEH) is somewhat different. Since SEH is endolymph, which can trigger hydrops symptoms. secondary to (that is, results from) an underlying An important starting point of this diet is to avoid disorder, the symptoms tend to be present more adding salt or sugar to food and to avoid eating continuously, rather than occurring in spontaneous prepared foods (those that come out of a can or attacks. However, they are often less violent, and other container). SEH may cause less damage to hearing and balance than does Ménière’s disease. THE FIVE GOALS OF TREATING SECONDARY ENDOLYMPHATIC HYDROPS Treatment of SEH has five goals: to stabilize the body’s fluid and electrolyte levels; to identify and 1. Stabilize the body’s fluid and electrolyte treat the underlying condition that is driving the levels. SEH; to improve daily symptoms; to manage 2. Identify and treat the underlying persistent symptoms and changes; and to maintain condition. quality of life. 3. Improve daily symptoms. 4. Manage persistent symptoms and changes. Goal 1: Stabilizing the body’s fluid and 5. Maintain quality of life. electrolyte levels Stabilizing the fluid and electrolyte levels may help reduce or relieve the symptoms. Modifications in Adequate fluid intake is another mainstay of the diet may be necessary in order to achieve such HDR. In order to function at its best, the body stabilization. needs lots of water—six to eight glasses spaced evenly throughout the day. It is also important to A hydrops diet regimen (HDR) often makes many anticipate and replace the additional fluid lost people with SEH feel significantly better without through perspiration during exercise, fever, or hot any other treatment. The HDR is the cornerstone weather. Other fluids—for example, low-sugar of stabilizing overall fluid levels. The most sodas, herbal teas, and low-sugar fruit and important aspect of this regimen is consistency. vegetable juices—may also make up part of the Eating a balanced diet in moderate amounts at daily allotment. Caffeine (found in coffee, tea, regular intervals—with meals and snacks of a some herbal teas, colas, chocolate, and some consistent size, eaten at about the same time every medications) and alcohol have strong diuretic day, without skipping meals or alternating tiny properties and may need to be restricted, because snacks with huge meals—helps the body’s fluid and they can cause the body to lose more fluid than it VESTIBULAR DISORDERS ASSOCIATION 5018 NE 15th Ave, Portland, OR 97211 (800) 837-8428 vestibular.org TAX-ID#93-0194340 has taken in. center of gravity. • Avoiding aspirin in high doses, which can Physicians may prescribe diuretics as part of cause temporary tinnitus. treatment, not to cause fluid loss, but rather to • Avoiding ibuprofen and other NSAIDS “push” the kidneys to excrete a constant amount (nonsteroidal anti-inflammatory drugs), which of urine throughout the day, thus helping to can have a direct effect on fluid balance and minimize large swings in the body’s fluid content. may increase symptoms in some SEH With diuretic use, drinking lots of water is im- patients. portant to avoid dehydration. Certain diuretics • Stopping smoking. Smoking constricts the require the use of a potassium supplement to single, tiny artery that feeds the ear, thus replace potassium lost through the urine. It is depriving it of oxygen and nutrients. important to discuss proper use of medication and • Maintaining general health by getting intake of food and water with the prescribing adequate exercise and sleep, both can help physician. with cardiovascular health to support the inner ear. Exercise can help the musculature Goal 2: Identifying and treating the underlying needed for balance stay active. condition This goal is complex and will likely involve both the Vestibular rehabilitation, a type of specialized otologist (ear specialist) and the primary care physical therapy for vestibular patients, can provider (internist, family practice physician, nurse improve tolerance for activity, overall energy level, practitioner, etc.). Once an underlying condition is and symptoms of dizziness and imbalance. The identified and treated, SEH symptoms tend to cognitive symptoms that often accompany improve over time with proper management. vestibular disorders—for instance, trouble with Hydrops associated with head trauma or ear concentration, short-term memory, reading, or surgery usually improves over the course of one to prioritizing tasks—may diminish as the hydrops is two years following the causative event. brought under control, but occupational and speech therapists can help if any symptoms Goal 3: Improving daily symptoms remain. With the use of the HDR and possibly also a diuretic, balance symptoms may improve dramat- Goal 4: Managing persistent symptoms and ically. Other medications may be used to help with changes persistent dizziness, nausea, or vomiting. If dizziness and vertigo become intractable, more aggressive measures may be considered. Other strategies to reduce the symptoms of SEH Medications or surgery can be used to selectively include: destroy the problematic inner ear structures. • Maintaining normal weight, or losing any There are various surgeries that may be excess weight. When a person is overweight, recommended. Endolymphatic decompression the vestibular system must struggle to deal procedures aim at relieving fluid pressure in the with a larger-than-normal and displaced inner ear. Another type of surgery is a VESTIBULAR DISORDERS ASSOCIATION 5018 NE 15th Ave, Portland, OR 97211 (800) 837-8428 vestibular.org TAX-ID#93-0194340 labyrinthectomy, which destroys the membranous miserable, yet “look normal” to friends and family. structures of the inner ear that detect gravity and Educating others about the illness can help them motion changes. Semi-circular canal plugging and better understand the difficulties and neurectomy (cutting the vestibular nerve between consequences of having a vestibular disorder. the ear and the brain) create mechanical changes Counseling or participating in a support group for that prevent abnormal inner ear signals from people with inner ear disorders may help to deal reaching the brain, thus reducing symptoms. These with the confusion or secondary depression that procedures do not cure the underlying disorder often accompanies these conditions. In any case, and are not without risk, but they may improve the physician and the physician’s staff remain the symptoms in some cases. patient’s primary resource in understanding and dealing with SEH. SEH does not usually result in significant hearing loss.
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