Report of Ten Cases of Perilymphatic Fistula And/Or Endolymphatic Hydrops Improved by Surgery

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Report of Ten Cases of Perilymphatic Fistula And/Or Endolymphatic Hydrops Improved by Surgery International Tinnitus Journal, Vol. 3, No. I, II-21 (1997) Tinnitus: Report of Ten Cases of Perilymphatic Fistula and/or Endolymphatic Hydrops Improved by Surgery Dudley J. Weider, M.D., F.A.C.S. Section of Otolaryngology, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire Abstract: Presented are ten cases of patients with perilymphatic fistula and/or endolymphatic hydrops who hadJinnitus as a major complaint. Tinnitus and its degree of severity often cor­ relate (;losely with the state of health or hydrodynamic integrity of the inner ear, as these cases illustrate. INTRODUCTION METHOD hen treating patients with perilymphatic Ten patients with Meniere's disease and/or PLF treated W fistula (PLF) and/or endolymphatic hy­ with surgery to control symptoms of disabling ver­ drops, vertigo and hearing loss (or fluctu­ tigo and hearing deterioration or fluctuation were se­ ation) are often the patient's main symptoms. The lected from cases brought to surgery during the past additional symptom of tinnitus is often a primary 22 years. Each case was chosen because the symp­ concern of the patient, but because it is less easily tom of tinnitus was a prominent complaint. Tinnitus quantified the physician ranks it, along with the symp­ varied in intensity according to the patient's primary tom of pressure or fullness, as lower in importance. symptoms. A review of early 1-3 and recent cases of PLF and/or The surgical modalities employed included sim­ endolymphatic hydrops encountered in my career sug­ ple exploratory tympanotomy with oval and/or round gests that tinnitus, and its various qualities of loudness window reinforcement, endolymphatic shunt, cochlear and pitch, may indicate the state of health of the inner aqueduct blockade and vestibular nerve section ei­ ear. The onset of tinnitus and its increase in intensity, ther by the posterior fossa or trans mastoid route. frequency or character may precede a serious escala­ Each case is presented along with the patient's tion in symptoms of vertigo, hearing loss and possibly medical history, physical findings and appropriate a perception of aural pressure or pain. Alternatively, laboratory, audiological and vestibular studies. The hearing improvement and resolution of vertigo often author's comments follow each case report. A gen­ coincide with diminution or the disappearance of tin­ eral discussion and conclusion are provided. nitus. This may happen as the result of medical and/or surgical treatment. Medical therapy includes head rest, salt restriction and vestibular suppression. Surgi­ CASE REPORTS cal modalities include simple oval and/or round win­ dow reinforcement, endolymphatic shunt, cochlear Case 1 aqueduct blockade and vestibular nerve section. This 45-year-old man was referred to the Dartmouth­ When these means are effective tinnitus will often di­ Hitchcock Medical Center (DHMC) in July 1976 minish, as illustrated by the following ten case reports. with a 7-year history and auditory findings of Me­ niere's disease. The patient had frequently occurring Reprint requests: Dr. Dudley Weider, Section of Otolaryn­ attacks of disabling vertigo, progressive deteriora­ gology, Dartmouth-Hitchcock Medical Center, One Medi­ tion in hearing (speech reception threshold [SRT] = cal Center Drive, Lebanon, N.H. 03756-0001. Telephone: 60 dB, speech discrimination score [SDS] = 68%), (603) 650-8122, Fax: (603) 650-4961. near-constant pressure and loud, low-pitched roaring 11 International Tinnitus Journal, Vol. 3, No.1, 1997 Weider tinnitus. Medical management (low-salt diet and di­ years later. She continued to have near-constant symp­ uretics) failed to control his vertigo. He had no aller­ toms in the right ear. Her hearing deteriorated to where gies and all blood chemistries were normal. An en­ her pure tone average (PTA) was 75 dB (range 250 dolymphatic sac-subarachnoid shunt was performed Hz to 2000 Hz) (SRT = 65 dB, SDS = 76%). She in August 1976. For a short time the patient's vertigo described the tinnitus as a fairly loud roar of "sea stopped and pressure and tinnitus lessened signifi­ shell" quality. cantly, but his vertiginous attacks resumed within 5 Approximately four years prior to her first visit to weeks. In October 1976 his ear was re-explored and DHMC, the patient began having similar symptoms the shunt revised. The patient was then asymptom­ involving her left ear. Hearing in that ear had deteri­ atic for about one month before he experienced one orated over four years to a level similar to that in the of his most severe and disabling attacks of vertigo, right ear (PTA = 70 dB, SRT = 60 dB, SDS = nausea and vomiting. Because of the chronic sever­ 88%). Because of a slightly improved PTA and SDS ity of his problem and his relatively poor hearing, a she regarded the left ear as her functional ear, and translabyrinthine vestibular nerve section was per­ was the ear in which she wore a hearing aid. At the formed in December 1976. This resulted in complete time of her presentation to the DHMC she was expe­ relief of this patient's vertigo, pressure and loud riencing approximately three minor attacks of ver­ roaring tinnitus. tigo per week, preceded by an increase in tinnitus and a decrease in hearing in her left ear. Medical Comment treatments had little success. Her allergic history was This operation was performed primarily to eliminate negative. the patient's disabling vertigo, but his greatest sense A left endolymphatic-subarachnoid shunt was of relief postoperatively was the absence of tinnitus. performed in February 1975. Postoperatively, the pa­ Pulec4 performed 151 cochlear nerve sections for in­ tient's vertigo and roaring tinnitus in the left ear dis­ tractable tinnitus, which resulted in complete relief appeared completely. Surprisingly, the tinnitus in her in 101 cases, significant improvement in 43 cases, right ear greatly diminished for about 18 months. and no improvement in 7 cases. In Pulec's series the Her SRT improved to 42 dB and her SDS to 92%. following conditions were present: Meniere's dis­ Her greatest audiometric improvements were at 500 ease (N = 84), chronic otitis media (N = 24), post­ Hz, 1 kHz and 2 kHz, where thresholds went from stapedectomy with inner ear injury (N = 11), trauma 75 Hz, 60 dB and 50 dB to 60 Hz and 30 dB and 35 (N = 18), and a variety of other conditions (N = dB, respectively. With some mild fluctuations her 14). All patients were believed to have tinnitus as the improved thresholds were maintained for 8 years. result of damage to the cochlea or cochlear nerve. After about 18 months, loud roaring tinnitus in­ Pulec4 stresses the need of a thorough preoperative creased in the right ear and eventually became nearly assessment, including hematological, audiological constant. The decision to perform an endolymphatic and radiological testing. A 5-mm segment of the shunt on the right ear was delayed because she had nerve is removed medial to the spiral ganglion. The no vertigo, only a progressively increasing and roar­ translabyrinthine approach was used in all but two ing tinnitus. patients who had a middle fossa approach. Pulec In August 1983 a right endolymphatic-subarach­ states that this approach is usually effective when the noid shunt was performed. Prior to performing the origin of the tinnitus is in the damaged cochlea.4 shunt the oval and round windows were observed for Shulman5 gives an excellent review of cochlear and/or the presence of a possible PLF. A very obvious ante­ vestibular nerve section for control of tinnitus. rior oval window PLF was found. Before performing the shunt the oval window region was scarified and Case 2 reinforced with areolar tissue. Postoperatively, the patient's tinnitus was nearly eliminated, and the oc­ This 39-year-old woman presented to the DHMC in casional momentary positional vertigo disappeared. October 1974 with a 14-year history of Meniere's During the next two years the patient's SDS, which disease which had become bilateral. Her right ear had never been above 68% during the previous nine was affected coincident with the birth of her first years, improved to 92%. child, when she developed severe nausea, vomiting, In February 1985 the patient experienced renewed vertigo and hearing loss. The symptoms subsided but roaring tinnitus and diminished hearing in her left returned coincident with the birth of her second child ear (the ear that had been operated on originally). A (12 years prior to her first visit to the DHMC), and PLF was strongly suspected due to an obvious PLF again coincident with the birth of her third child 2 found in the recently explored right ear. 12 Tinnitus: Report of Ten Cases International Tinnitus Journal, Vol. 3, No.1, 1997 The left ear was explored in March 1985. Upon at the hair cell increased to + 33 dB (in reference to opening the left middle ear, fluid was found within auditory threshold) for loose coupling. Tondorf7 con­ the oval window niche; the fluid accumulated repeat­ cluded that the increased noise level at the hair cell edly after aspiration. During a minor stapes manipu­ input, an increment of 55 dB that is caused by the lation the patient reported a sudden drop in her hear­ partial decoupling of the stereocilia from the tecto­ ing. Both windows were reinforced and the case rial membrane, ought to be perceived as tinnitus. In terminated. Postoperatively, the patient's hearing endolymphatic hydrops the decoupling is maximal in thresholds were greatly elevated and her SDS fell to the region where the basilar membrane is the largest 0%. Vertigo was eliminated and tinnitus stopped. In­ (i.e., the apical region). Blebs on the stereocilia and terestingly, at this point discrimination in the right development of "giant" stereocilia have been dem­ ear rose to 92%.
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