OXCT1 Antibody Cat. No.: 30-414

OXCT1 Antibody

Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human OXCT1.

TESTED APPLICATIONS: ELISA, WB

OXCT1 antibody can be used for detection of OXCT1 by ELISA at 1:62500. OXCT1 antibody APPLICATIONS: can be used for detection of OXCT1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1201 - HeLa Cell Lysate

PREDICTED MOLECULAR 52 kDa WEIGHT:

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PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: OXCT1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: OXCT1

ALTERNATE NAMES: OXCT1, OXCT, SCOT

ACCESSION NO.: NP_000427

PROTEIN GI NO.: 4557817

GENE ID: 5019

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. BACKGROUND: The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

REFERENCES: 1) Fukao, T., (2007) Mol. Genet. Metab. 92 (3), 216-221.

ANTIBODIES FOR RESEARCH USE ONLY.

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