Hans Asperger, National Socialism, and “Race Hygiene” in Nazi-Era Vienna Herwig Czech
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Human Genetic Basis of Interindividual Variability in the Course of Infection
Human genetic basis of interindividual variability in the course of infection Jean-Laurent Casanovaa,b,c,d,e,1 aSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065; bHoward Hughes Medical Institute, New York, NY 10065; cLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Inserm U1163, Necker Hospital for Sick Children, 75015 Paris, France; dImagine Institute, Paris Descartes University, 75015 Paris, France; and ePediatric Hematology and Immunology Unit, Assistance Publique–Hôpitaux de Paris, Necker Hospital for Sick Children, 75015 Paris, France This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2015. Contributed by Jean-Laurent Casanova, November 2, 2015 (sent for review September 15, 2015; reviewed by Max D. Cooper and Richard A. Gatti) The key problem in human infectious diseases was posed at the immunity (cell-autonomous mechanisms), then of cell-extrinsic turn of the 20th century: their pathogenesis. For almost any given innate immunity (phagocytosis of pathogens by professional cells), virus, bacterium, fungus, or parasite, life-threatening clinical disease and, finally, of cell-extrinsic adaptive immunity (somatic di- develops in only a small minority of infected individuals. Solving this versification of antigen-specific cells). Understanding the patho- infection enigma is important clinically, for diagnosis, prognosis, genesis of infectious diseases, particularly -
The Nazi Legacy of Pernkopf's Atlas
J. A. Hartsock & E. S. Beckman . Conatus 4, no. 2 (2019): 317-339 DOI: http://dx.doi.org/10.12681/cjp.21076 A Human Paradox: The Nazi Legacy of Pernkopf’s Atlas Jane A. Hartsock1 and Emily S. Beckman2 1Indiana University Health, USA E-mail address: [email protected] ORCID ID: https://orcid.org/0000-0002-2359-7706 2Indiana University - Purdue University, USA E-mail address: [email protected] ORCID ID: https://orcid.org/0000-0003-4966-0950 Abstract Eduard Pernkopf’s Atlas of Topographical and Applied Human Anatomy is a four-volume anatomical atlas published between 1937 and 1963, and it is generally believed to be the most comprehensive, detailed, and accurate anatomy textbook ever created. However, a 1997 investigation into “Pernkopf’s Atlas,” raised troubling questions regarding the author’s connection to the Nazi regime and the still unresolved issue of whether its illustrations relied on Jewish or other political prisoners, including those executed in Nazi concentration camps. Following this investigation, the book was removed from both anatomy classrooms and library bookshelves. A debate has ensued over the book’s continued use, and justification for its use has focused on two issues: (1) there is no definitive proof the book includes illustrations of concentration camp prisoners or Jewish individuals in particular, and (2) there is no contemporary equivalent to this text. However, both points fail to address the central importance of the book, not simply as part of anatomy instruction, but also as a comprehensive historical narrative with important ethical implications. Having encountered a first edition copy, these authors were given a unique opportunity to engage with the text through the respective humanities lenses of history, ethics, and narrative. -
Sensory Integration Used with Children with Asperger's Syndrome
Sensory Integration Used with Children with Asperger’s Syndrome Analisa L. Smith, Ed.D. Abstract Sensory Integration Program on Children with Asperger’s Syndrome This literature review will document the effects of a parent implemented Sensory Integration Program upon children diagnosed with Asperger’s Syndrome in order to discern its influence upon these children’s overall ability to attend to learning and social development. The infrequency of research on Asperger’s Syndrome and sensory-based programs indicates a need for further study into the potential relationship between evaluation regarding Asperger’s Syndrome and sensory- based approaches. The following literature review reflects the findings of current research within the fields of psychology, education, neurology, medicine, and occupational therapy as they pertain to Asperger’s Syndrome. Asperger’s Syndrome Volkmar and Klin (2000) state that Asperger’s Syndrome (AS) is a neuro- developmental disability that can be distinguished by limited interests and social deficits. Viennese pediatrician Hans Asperger (1943) identified the features of AS in the early 1940s and Wing (1981) gave further details about the disability's features decades later. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR, 2004), Asperger’s is classified as a Pervasive Developmental Disorder (PDD). Although, Asperger’s differs from other PDDs in that children diagnosed with AS meet normal developmental milestones in the area of language acquisition and cognitive ability. There is a continued need to research Asperger’s Syndrome (Bashe, Kirby, & Attwood, 2001). Although an AS diagnosis does not look at sensory processing deficits (DSM-IV-TR, 2004), numerous studies note that sensory deficits are common in people with AS (Barnhill, 2001; Dunn, et. -
How the Pernkopf Controversy Facilitated a Historical and Ethical
Clinical Anatomy 19:91–100 (2006) REVIEW How the Pernkopf Controversy Facilitated a Historical and Ethical Analysis of the Anatomical Sciences in Austria and Germany: A Recommendation for the Continued Use of the Pernkopf Atlas SABINE HILDEBRANDT* Division of Anatomical Sciences, Office of Medical Education, University of Michigan Medical School, Ann Arbor, Michigan Eduard Pernkopf’s Topographical Anatomy of Man has been a widely used standard work of anatomy for over sixty years. International inquiries about the National Socialist (NS) political background of Eduard Pernkopf and the use of bodies of NS victims for the atlas were first directed at the University of Vienna in 1996. A public discussion about the fur- ther use of the book followed and led to the creation of the Senatorial Project of the Uni- versity of Vienna in 1997. This historical research project confirmed the strong NS affilia- tion of Pernkopf and revealed the delivery of at least 1,377 bodies of executed persons to the Anatomical Institute of Vienna during the NS time. The possible use of these bodies as models cannot be excluded for up to half of the approximately 800 plates in the atlas. In addition tissue specimens from NS victims were found and removed from the collec- tions of the Viennese Medical School and received a burial in a grave of honor. The Pern- kopf controversy facilitated the historical and ethical analysis of the anatomical sciences in Austria and Germany during the NS regime. The continued use of the Pernkopf atlas is not only justifiable but desirable as a tool in the teaching of anatomy, history, and ethics. -
Grey Anatomy: Reconsidering the Legacy of Nazi Medicine Through Eduard Pernkopf's Topographische Anatomie Des Menschen
The Pernkopf anatomy atlas is extant... and is now actively sold and distributed by Urban and Schwarzenberg. This offends me. The Nazis, Nazi physicians, and their era represented a horrible, unprecedented evil, repugnant to all humanity and medical tradition.l This outstanding book should be of great value to anatomists and surgeons. It is in a class of its own and will continue to be valued.2 I would not ban this book, and indeed I would encourage its printing and use. In future, I would insist that it be printed in its 1941 edition, with all of the swastikas SS symbols. There must be a note in the fly leaf explaining the origin of the bodies and the book's history. We can not alter history but we can publicize it.3 'Richard S. Panush, "Nazi Origins of an Anatomy text: the Pernkopf Text [letter]," Journal of the American Medical Association 276, no.20 (1996): 1633- 1634. Richard S. Snell, "Pernkopf Anatomy: Atlas of Topographic and Applied Human Anatomy," review of Atlas of Topographical and Applied Human Anatomy, Volume I: Head and Neck. Ed. Werner Platzer. 3rd Revised Edition. New England Journal of Medicine 323, no. 3 (1990): 205. 3Paul M. Allen, "On First Looking into Pernkopf s Atlas: Some Further Comments," Archives of Dermatology 138, no. 2 (2002): 266-267. UNIVERSITY OF ALBERTA GREY ANATOMY: RECONSIDERING THE LEGACY OF NAZI MEDICINE THROUGH EDUARD PERNKOPF'S TOPOGRAPHISCHE ANATOMIE DES MENSCHEN BY DAWN ALEXANDREA BERRY \ , A THESIS SUBMITTED TO THE FACULTY OF GRADUATE STUDIES AND RESEARCH IN PARTIAL FULFILLMENT OF THE DEGREE -
Recognizing the Past in the Present
INTRODUCTION Recognizing the Past in the Present Sabine Hildebrandt, Miriam Offer, and Michael A. Grodin The past matters, as it continues to reach into the present and infl uence the fu- ture. The acknowledgment that this holds true for the legacies of medicine in the Holocaust has long been denied by the medical professions after World War II, to the point that systematic research into this history only began in the 1980s.1 Too easy was it to point to the results of the Nuremberg Doctors Trial and claim that only a criminal few had been responsible for the atrocities committed by physi- cians in the extermination of those considered unworthy of life and the Euro- pean Jewry.2 Too easy was it to claim that medicine itself had been abused by the criminal regime of National Socialism.3 Research into the complicity of medical scientists, physicians, nurses, midwives, and other health personnel gained mo- mentum only after the perpetrators of crimes—and in academic medicine often their pupils too—had left their positions that they had reclaimed after the war. And the potential failings of the theory of scientifi c medicine itself have come into the focus of historical analysis only late.4 Many threads of this history are currently under investigation, their roots traced back to the time before 1933, and they need to be placed in the larger framework of continuities of persons, thought patterns and epistemology, and legacies that include the trauma of vic- tims, the published results, and the physical remains of Nazi research. These continuities -
Xii World Asthma, Allergy & Copd Forum
XII WORLD ASTHMA, ALLERGY & COPD FORUM Saint Petersburg, Russia June 29–July 2, 2019 SAINT PETERSBURG SAINT PROGRAM World Immunopathology XIII WORLD ASTHMA, Organization (WIPO) ALLERGY & COPD FORUM Saint-Petersburg, Russia July 2–5, 2020 General Information St. Pet The World Immunopathology Organization (WIPO) is a professional, non-profit organization. WIPO was created in December 2002, at the I World Congress on Immunopathology in Singapore. During these years, WIPO successfully organized many international congresses and regional and national meetings throughout See you in Saint Petersburg in 2020! the world all promoting basic and clinical research and giving an opportunity for exchanging ideas. WIPO is aimed at collecting and disseminating scientific information and providing training and continuous education in various fields of immunopathology. Aims and Mission Nowadays, immunopathology has become a multidisciplinary problem. The WIPO global mission is to promote through education and research activities worldwide: – basic and clinical research in experimental and clinical immunology, allergy and asthma, autoimmunity, immunodeficiency, AIDS, immunobiotechnology, – prevention and treatment of different manifestations of immunopathology—immune-associated disorders, – excellence in patient care in this very important area of medicine and to establish communication between specialists in various fields of medical science and practice. e We encourage to join WIPO national and regional societies as well as individual members—doctors -
Reassessing Nazi Human Experiments and Coerced Research, 1933-1945: New Findings, Interpretations and Problems
Reassessing Nazi Human Experiments and Coerced Research, 1933-1945: New Findings, Interpretations and Problems Thursday 4 July – Sunday 7 July, 2013 Organised by Paul Weindling and Marius Turda (Oxford Brookes University), and Volker Roelcke (University of Giessen). Hosted at Wadham College, Oxford Contact: Simon Wilson: [email protected] Prof. Paul Weindling: [email protected] Cover image: These portraits depict six individuals on the brink of tragedy. Clockwise from the top left, pictured are: Bienem Gold, Estera Fuerstenzell, Beti Fuerstenzell, Moses Fuerstenzell, Lea Fuerstenzell, and Sita Fuerstenzell. The photographs were taken as part of a racial survey of the Tarnów ghetto, Poland, in 1942. The survey was a joint venture of the Institut fuer deutsche Ostarbeit, and Dr. Dora Kahlich-Koener, a racial anthropologist from the University of Vienna. Mere weeks after these photographs were taken, the mass killings and mass deportation of Tarnów's thousands of Jewish residents to Belzec extermination camp began The symposia are supported by Wellcome Trust, the Rabbi Israel Miller Fund for Shoah Research of the Conference on Jewish Material Claims Against Germany, Oxford Brookes University, and the University of Giessen. 1 I “Reassessing Nazi Human Experiments and Coerced Research, 1933- 1945: New Findings, Interpretations and Problems” Schedule for Thursday July 4th 15:30 – 16:45: Tea and Coffee in the Trap Room 17:00 – Introductory Session: Victims as Populations 19:00 Chair: Volker Roelcke (University of Giessen) -
The German-Jewish Experience Revisited Perspectives on Jewish Texts and Contexts
The German-Jewish Experience Revisited Perspectives on Jewish Texts and Contexts Edited by Vivian Liska Editorial Board Robert Alter, Steven E. Aschheim, Richard I. Cohen, Mark H. Gelber, Moshe Halbertal, Geoffrey Hartman, Moshe Idel, Samuel Moyn, Ada Rapoport-Albert, Alvin Rosenfeld, David Ruderman, Bernd Witte Volume 3 The German-Jewish Experience Revisited Edited by Steven E. Aschheim Vivian Liska In cooperation with the Leo Baeck Institute Jerusalem In cooperation with the Leo Baeck Institute Jerusalem. An electronic version of this book is freely available, thanks to the support of libra- ries working with Knowledge Unlatched. KU is a collaborative initiative designed to make high quality books Open Access. More information about the initiative can be found at www.knowledgeunlatched.org This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License. For details go to http://creativecommons.org/licenses/by-nc-nd/4.0/. ISBN 978-3-11-037293-9 e-ISBN (PDF) 978-3-11-036719-5 e-ISBN (EPUB) 978-3-11-039332-3 ISSN 2199-6962 Library of Congress Cataloging-in-Publication Data A CIP catalog record for this book has been applied for at the Library of Congress. Bibliographic information published by the Deutsche Nationalbibliothek The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data are available on the Internet at http://dnb.dnb.de. © 2015 Walter de Gruyter GmbH, Berlin/Boston Cover image: bpk / Staatsbibliothek zu Berlin Typesetting: PTP-Berlin, Protago-TEX-Production GmbH, Berlin Printing and binding: CPI books GmbH, Leck ♾ Printed on acid-free paper Printed in Germany www.degruyter.com Preface The essays in this volume derive partially from the Robert Liberles International Summer Research Workshop of the Leo Baeck Institute Jerusalem, 11–25 July 2013. -
Information Paper
INFORMATION PAPER INTRODUCING THE DSM-5 DIAGNOSTIC CRITERIA FOR AUTISM SPECTRUM DISORDER What is the DSM-5? The Diagnostic and Statistical Manual of Mental Disorders (the DSM) is developed by the American Psychiatric Association to provide the criteria by which clinicians define and diagnose various psychiatric and developmental conditions, including autism spectrum disorders. The newest edition of this manual, the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-5)[1], was released in May 2013, after ten years of revision, including field trials, and input from the mental health and medical communities, patients and their families and members of the public. As yet, there are no biological tests (e.g., genetic tests, brain scans) that can be used to reliably diagnose conditions on the autism spectrum. Diagnosis is therefore made on the basis of a set of behavioural symptoms. Our understanding of conditions on the autism spectrum have continued to evolve since they were first recognised by Leo Kanner in 1943[2] and Hans Asperger in 1944[3]. What changes have been made for autism spectrum disorders in DSM-5? There have been a number of changes made to the new edition, most notably: . The diagnostic labels Autistic Disorder, Asperger’s Disorder, PDD-NOS and Childhood Disintegrative Disorder that were in the previous DSM edition: the Diagnostic and Statistical Manual of Mental Disorders – Fourth Edition Text Revision (DSM-IV-TR)[4] under the heading Pervasive Developmental Disorders will no longer be used. These subcategories have been merged into the single broader diagnostic category of Autism Spectrum Disorder (ASD). -
LARSON-DISSERTATION-2020.Pdf
THE NEW “OLD COUNTRY” THE KINGDOM OF YUGOSLAVIA AND THE CREATION OF A YUGOSLAV DIASPORA 1914-1951 BY ETHAN LARSON DISSERTATION Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in History in the Graduate College of the University of Illinois at Urbana-Champaign, 2020 Urbana, Illinois Doctoral Committee: Professor Maria Todorova, Chair Professor Peter Fritzsche Professor Diane Koenker Professor Ulf Brunnbauer, University of Regensburg ABSTRACT This dissertation reviews the Kingdom of Yugoslavia’s attempt to instill “Yugoslav” national consciousness in its overseas population of Serbs, Croats, and Slovenes, as well as resistance to that same project, collectively referred to as a “Yugoslav diaspora.” Diaspora is treated as constructed phenomenon based on a transnational network between individuals and organizations, both emigrant and otherwise. In examining Yugoslav overseas nation-building, this dissertation is interested in the mechanics of diasporic networks—what catalyzes their formation, what are the roles of international organizations, and how are they influenced by the political context in the host country. The life of Louis Adamic, who was a central figure within this emerging network, provides a framework for this monograph, which begins with his arrival in the United States in 1914 and ends with his death in 1951. Each chapter spans roughly five to ten years. Chapter One (1914-1924) deals with the initial encounter between Yugoslav diplomats and emigrants. Chapter Two (1924-1929) covers the beginnings of Yugoslav overseas nation-building. Chapter Three (1929-1934) covers Yugoslavia’s shift into a royal dictatorship and the corresponding effect on its emigration policy. -
Timeline of Immunology
TIMELINE OF IMMUNOLOGY 1549 – The earliest account of inoculation of smallpox (variolation) occurs in Wan Quan's (1499–1582) 1718 – Smallpox inoculation in Ottoman Empire realized by West. Lady Mary Wortley Montagu, the wife of the British ambassador to Constantinople, observed the positive effects of variolation on the native population and had the technique performed on her own children. 1796 – First demonstration of smallpox vaccination (Edward Jenner) 1837 – Description of the role of microbes in putrefaction and fermentation (Theodore Schwann) 1838 – Confirmation of the role of yeast in fermentation of sugar to alcohol (Charles Cagniard-Latour) 1840 – Proposal of the germ theory of disease (Jakob Henle) 1850 – Demonstration of the contagious nature of puerperal fever (childbed fever) (Ignaz Semmelweis) 1857–1870 – Confirmation of the role of microbes in fermentation (Louis Pasteur) 1862 – Phagocytosis (Ernst Haeckel) 1867 – Aseptic practice in surgery using carbolic acid (Joseph Lister) 1876 – Demonstration that microbes can cause disease-anthrax (Robert Koch) 1877 – Mast cells (Paul Ehrlich) 1878 – Confirmation and popularization of the germ theory of disease (Louis Pasteur) 1880 – 1881 -Theory that bacterial virulence could be attenuated by culture in vitro and used as vaccines. Proposed that live attenuated microbes produced immunity by depleting host of vital trace nutrients. Used to make chicken cholera and anthrax "vaccines" (Louis Pasteur) 1883 – 1905 – Cellular theory of immunity via phagocytosis by macrophages and microphages (polymorhonuclear leukocytes) (Elie Metchnikoff) 1885 – Introduction of concept of a "therapeutic vaccination". Report of a live "attenuated" vaccine for rabies (Louis Pasteur and Pierre Paul Émile Roux). 1888 – Identification of bacterial toxins (diphtheria bacillus) (Pierre Roux and Alexandre Yersin) 1888 – Bactericidal action of blood (George Nuttall) 1890 – Demonstration of antibody activity against diphtheria and tetanus toxins.