FAQ: Questions You May Have About COVID-19 Vaccines
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
An Atlas of Potentially Water-Related Diseases in South Africa
AN ATLAS OF POTENTIALLY WATER-RELATED DISEASES IN SOUTH AFRICA Volume 2 Bibliography Report to the WATER RESEARCH COMMISSION by N Coetzee and D E Bourne Department of Community Health University of Cape Town Medical School WRC Report no. 584/2/96 ISBN 1 86845 245 X ISBN Set No 1 86845 246 8 1 CONTENTS VOLUME 2 BIBLIOGRAPHY 1 Introduction 2 2 Amoebiasis 3 3 Arthropod-borne viral diseases 7 4 Cholera 10 5 Diarrhoeal diseases in childhood 14 6 Viral hepatitis A and E 17 7 Leptospirosis 20 3 Pediculosis 22 9 Malaria 23 10 Poliomyelitis 29 11 Scabies 33 12 Schistosomiasis 35 13 Trachoma 39 14 Typhoid Fever 42 15 Intestinal helminthiasis 46 1. INTRODUCTION As many professionals involved in the management of water resources do not have a medical or public health background, it was thought that an explanatory bibliography of the major water related diseases in South Africa would be of use. Each section of the bibliography has (where appropriate) the following sections: 1. Aetiology 2. Transmission 3. Preventive and curative steps 4. South African data 5. References The MEDLINE data base of the national Library of Medicine, Washington DC, and the WATERLIT data base of the CSIR were searched. These were supplemented by South African journals and reports not appearing in the MEDLINE data base. 3 2. AMOEBIASIS 2.1. Aetiology The protozoan parasite Entamoeba histolytica which causes amoebiasis may exist as a hardy infective cyst or a more fragile and potentially pathogenic trophozoite (the "amoebic" form). Amoebiasis most commonly affects the colon and rectum as primary sitas of infection, with extraintestinal (most commonly liver abscesses), local or systemic, spread possible if not treated early. -
Estimating the Instantaneous Asymptomatic Proportion with a Simple Approach: Exemplified with the Publicly Available COVID-19 Surveillance Data in Hong Kong
ORIGINAL RESEARCH published: 03 May 2021 doi: 10.3389/fpubh.2021.604455 Estimating the Instantaneous Asymptomatic Proportion With a Simple Approach: Exemplified With the Publicly Available COVID-19 Surveillance Data in Hong Kong Chunyu Li 1†, Shi Zhao 2,3*†, Biao Tang 4,5, Yuchen Zhu 1, Jinjun Ran 6, Xiujun Li 1*‡ and Daihai He 7*‡ 1 2 Edited by: Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China, JC 3 Catherine Ropert, School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China, Chinese University of 4 Federal University of Minas Hong Kong (CUHK) Shenzhen Research Institute, Shenzhen, China, School of Mathematics and Statistics, Xi’an Jiaotong 5 Gerais, Brazil University, Xi’an, China, Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, ON, Canada, 6 School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Reviewed by: Hong Kong, China, 7 Department of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China Mohammad Javanbakht, Baqiyatallah University of Medical Sciences, Iran Background: The asymptomatic proportion is a critical epidemiological characteristic Changjing Zhuge, that modulates the pandemic potential of emerging respiratory virus, which may vary Beijing University of Technology, China *Correspondence: depending on the nature of the disease source, population characteristics, source–host Daihai He interaction, and environmental factors. [email protected] Xiujun Li Methods: We developed a simple likelihood-based framework to estimate the [email protected] instantaneous asymptomatic proportion of infectious diseases. Taking the COVID-19 Shi Zhao epidemics in Hong Kong as a case study, we applied the estimation framework [email protected] to estimate the reported asymptomatic proportion (rAP) using the publicly available † These authors share first authorship surveillance data. -
Food Handler Exclusion Guidelines
Food Handler Exclusion Guidelines A guide for determining suitable exclusion periods for ill food handlers November 2017 Food handler exclusion guidelines Published by the State of Queensland (Queensland Health), November 2017 This document is licensed under a Creative Commons Attribution 3.0 Australia licence. To view a copy of this licence, visit creativecommons.org/licenses/by/3.0/au © State of Queensland (Queensland Health) 2017 You are free to copy, communicate and adapt the work, as long as you attribute the State of Queensland (Queensland Health). For more information contact: Food Safety Standards and Regulation, Department of Health, GPO Box 48, Brisbane QLD 4001, email [email protected], phone 07 3328 9310. An electronic version of this document is available at www.health.qld.gov.au. Disclaimer: The content presented in this publication is distributed by the Queensland Government as an information source only. The State of Queensland makes no statements, representations or warranties about the accuracy, completeness or reliability of any information contained in this publication. The State of Queensland disclaims all responsibility and all liability (including without limitation for liability in negligence) for all expenses, losses, damages and costs you might incur as a result of the information being inaccurate or incomplete in any way, and for any reason reliance was placed on such information. Food Handler Exclusion Guidelines - ii - Contents 1. Introduction ............................................................................................... -
PEDIARIX Is a Vaccine
HIGHLIGHTS OF PRESCRIBING INFORMATION • If Guillain-Barré syndrome occurs within 6 weeks of receipt of a prior These highlights do not include all the information needed to use vaccine containing tetanus toxoid, the decision to give PEDIARIX should PEDIARIX safely and effectively. See full prescribing information for be based on potential benefits and risks. (5.2) PEDIARIX. • The tip caps of the prefilled syringes contain natural rubber latex which may cause allergic reactions. (5.3) PEDIARIX [Diphtheria and Tetanus Toxoids and Acellular Pertussis • Syncope (fainting) can occur in association with administration of Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus injectable vaccines, including PEDIARIX. Procedures should be in place Vaccine], Suspension for Intramuscular Injection to avoid falling injury and to restore cerebral perfusion following Initial U.S. Approval: 2002 syncope. (5.4) • If temperature ≥105°F, collapse or shock-like state, or persistent, ----------------------------- INDICATIONS AND USAGE ---------------------------- PEDIARIX is a vaccine indicated for active immunization against diphtheria, inconsolable crying lasting ≥3 hours have occurred within 48 hours after tetanus, pertussis, infection caused by all known subtypes of hepatitis B virus, receipt of a pertussis-containing vaccine, or if seizures have occurred and poliomyelitis. PEDIARIX is approved for use as a 3-dose series in infants within 3 days after receipt of a pertussis-containing vaccine, the decision born of hepatitis B surface antigen (HBsAg)-negative mothers. PEDIARIX to give PEDIARIX should be based on potential benefits and risks. (5.5) may be given as early as 6 weeks of age through 6 years of age (prior to the • For children at higher risk for seizures, an antipyretic may be 7th birthday). -
Global Dynamics of a Vaccination Model for Infectious Diseases with Asymptomatic Carriers
MATHEMATICAL BIOSCIENCES doi:10.3934/mbe.2016019 AND ENGINEERING Volume 13, Number 4, August 2016 pp. 813{840 GLOBAL DYNAMICS OF A VACCINATION MODEL FOR INFECTIOUS DISEASES WITH ASYMPTOMATIC CARRIERS Martin Luther Mann Manyombe1;2 and Joseph Mbang1;2 Department of Mathematics, Faculty of Science University of Yaounde 1, P.O. Box 812 Yaounde, Cameroon 1;2;3; Jean Lubuma and Berge Tsanou ∗ Department of Mathematics and Applied Mathematics University of Pretoria, Pretoria 0002, South Africa (Communicated by Abba Gumel) Abstract. In this paper, an epidemic model is investigated for infectious dis- eases that can be transmitted through both the infectious individuals and the asymptomatic carriers (i.e., infected individuals who are contagious but do not show any disease symptoms). We propose a dose-structured vaccination model with multiple transmission pathways. Based on the range of the explic- itly computed basic reproduction number, we prove the global stability of the disease-free when this threshold number is less or equal to the unity. Moreover, whenever it is greater than one, the existence of the unique endemic equilibrium is shown and its global stability is established for the case where the changes of displaying the disease symptoms are independent of the vulnerable classes. Further, the model is shown to exhibit a transcritical bifurcation with the unit basic reproduction number being the bifurcation parameter. The impacts of the asymptomatic carriers and the effectiveness of vaccination on the disease transmission are discussed through through the local and the global sensitivity analyses of the basic reproduction number. Finally, a case study of hepatitis B virus disease (HBV) is considered, with the numerical simulations presented to support the analytical results. -
The Hepatitis B Vaccine Is the Most Widely Used Vaccine in the World, with Over 1 Billion Doses Given
Hepatitis B Vaccine Protect Yourself and Those You Love What is Hepatitis B? Hepatitis B is the most common serious liver infection in the world. It is caused by the hepatitis B virus (HBV), which attacks liver cells and can lead to liver failure, cirrhosis (scarring), or liver cancer later in life. The virus is transmitted through direct contact with infected blood and bodily fluids, and from an infected woman to her newborn at birth. Is there a safe vaccine for hepatitis B? YES! The good news is that there is a safe and effective vaccine for hepatitis B. The vaccine is a series, typically given as three shots over a six-month period that will provide a lifetime of protection. You cannot get hepatitis B from the vaccine – there is no human blood or live virus in the vaccine. The hepatitis B vaccine is the most widely used vaccine in the world, with over 1 billion doses given. The hepatitis B vaccine is the first "anti-cancer" vaccine because it can help prevent liver cancer! Who should be vaccinated against hepatitis B? The World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) recommend the hepatitis B vaccine for all newborns and children up to 18 years of age, and all high-risk adults. All infants should receive the first dose of the vaccine in the delivery room or in the first 24 hours of life, preferably within 12 hours. (CDC recommends the first dose within 12 hours vs. the WHO recommendation of 24 hours.) The HBV vaccine is recommended to anyone who is at high risk of infection. -
COVID-19 Scientific Advisory Group Rapid Response Report
COVID-19 Scientific Advisory Group Rapid Response Report Key Research Question: What is the evidence supporting the possibility of asymptomatic transmission of SARS-CoV-2? [Updated April 13, 2020] Context • Asymptomatic transmission (including pre-symptomatic transmission) of SARS-CoV-2 could reduce the effectiveness of control measures that are related to symptom onset (isolation, face masks and enhanced hygiene for symptomatic persons, and parameters of contact tracing), particularly if routine practices, including the use of diligent hand hygiene and environmental disinfection after patient encounters are not adhered to. • Concerns regarding asymptomatic transmission are driven by observations in various populations that suggested 18% – 50.5% of people with positive RT-PCR in various settings were asymptomatic at testing, and epidemiologic modelling suggesting that asymptomatic or presymptomatic cases may be responsible for potentially significant transmission, with a wide range of estimates from 0% to 44%. However, this is discrepant from epidemiologic descriptions from the initial epidemic in China and elsewhere which do not suggest that asymptomatic transmission is a major driver for the COVID19 epidemic. • The Public Health Agency of Canada (PHAC) has indicated that wearing a non-medical (cloth) mask in the community has not been proven to protect the person wearing it, however, it can be an additional measure to protect others around you, and might be useful in situations where physical distancing is not possible (e.g., grocery stores and public transit). (Tasker, 2020; Public Health Agency of Canada, 2020) Key Messages from the Evidence Summary • It is biologically plausible that SARS-CoV-2 can be transmitted when patients are asymptomatic, pre-symptomatic, or mildly symptomatic (potentially from 2.5 days prior to onset of symptoms), based on the finding that RT-PCR levels are high early in infection. -
Engerix-B Data Sheet
NEW ZEALAND DATA SHEET 1. PRODUCT NAME ENGERIX-B 20 micrograms/mL, suspension for injection. ENGERIX-B paediatric 10 micrograms/0.5 mL, suspension for injection. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION ENGERIX-B paediatric dose: 10 microgram (µg) dose vaccine 1 dose (0.5 mL) contains: Hepatitis B surface antigen 1, 2 10 micrograms 1Adsorbed on aluminium hydroxide, hydrated Total: 0.25 milligrams Al3+ 2Produced in yeast cells (Saccharomyces cerevisiae) by recombinant DNA technology ENGERIX-B: 20 microgram (µg) dose vaccine 1 dose (1 mL) contains: Hepatitis B surface antigen1, 2 20 micrograms 1Adsorbed on aluminium hydroxide, hydrated Total: 0.50 milligrams Al3+ 2Produced in yeast cells (Saccharomyces cerevisiae) by recombinant DNA technology The vaccine is highly purified, and meets the WHO requirements for recombinant hepatitis B vaccines. No substances of human origin are used in its manufacture. For the full list of excipients, see section 6.1 List of excipients. 3. PHARMACEUTICAL FORM Suspension for injection. ENGERIX-B is a turbid white suspension. Upon storage, a fine white deposit with a clear colourless supernatant may be observed. 4. CLINICAL PARTICULARS 4.1 Therapeutic indications ENGERIX-B is indicated for active immunisation against hepatitis B virus infection. As part of the national immunisation schedule, the New Zealand Ministry of Health* recommend all infants, unvaccinated children up to the age of 16 years, and household and sexual contacts of known hepatitis B carriers receive a primary course of vaccination against hepatitis B. 1 Immunisation is also recommended for seronegative persons who are at substantial risk and have been demonstrated or judged to be susceptible to the hepatitis B virus (HBV). -
Diphtheria, Tetanus, Pertussis, Polio, Hib and Hepatitis B Vaccine for Babies and Children
Diphtheria, Tetanus, Pertussis, Polio, Hib and Hepatitis B vaccine for babies and children This leaflet tells you about the DTaP/IPV/Hib/ HepB vaccine, also known as “6 in 1” as it protects against six diseases, diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b and hepatitis B (HepB) disease. What does the vaccine protect against? Diphtheria Diphtheria is a serious disease that usually begins with a sore throat and can quickly cause breathing problems. It can damage the heart and nervous system and, in severe cases, can kill. Before diphtheria vaccine was introduced in the UK, there were up to 70,000 cases of diphtheria and around 5,000 deaths a year. Diphtheria can be spread from person to person through close contact. Tetanus Tetanus is a disease affecting the nervous system which can cause muscle spasms and breathing problems and can kill. It is caused when germs found in soil and manure get into the body through wounds or burns. Tetanus cannot be passed from person to person. 2 Published June 2018 Pertussis (whooping cough) Whooping cough is a disease that can cause long bouts of coughing and choking, making it hard to breathe. It can last for up to 10 weeks and babies under one year of age are most at risk. The disease is very serious and can kill. Before the pertussis vaccine was introduced, the average number of cases reported each year in the UK was 120,000 and 92 children died in the year before the vaccine was introduced. Whooping cough is usually spread by coughs and sneezes. -
Zoonotic Diseases Fact Sheet
ZOONOTIC DISEASES FACT SHEET s e ion ecie s n t n p is ms n e e s tio s g s m to a a o u t Rang s p t tme to e th n s n m c a s a ra y a re ho Di P Ge Ho T S Incub F T P Brucella (B. Infected animals Skin or mucous membrane High and protracted (extended) fever. 1-15 weeks Most commonly Antibiotic melitensis, B. (swine, cattle, goats, contact with infected Infection affects bone, heart, reported U.S. combination: abortus, B. suis, B. sheep, dogs) animals, their blood, tissue, gallbladder, kidney, spleen, and laboratory-associated streptomycina, Brucellosis* Bacteria canis ) and other body fluids causes highly disseminated lesions bacterial infection in tetracycline, and and abscess man sulfonamides Salmonella (S. Domestic (dogs, cats, Direct contact as well as Mild gastroenteritiis (diarrhea) to high 6 hours to 3 Fatality rate of 5-10% Antibiotic cholera-suis, S. monkeys, rodents, indirect consumption fever, severe headache, and spleen days combination: enteriditis, S. labor-atory rodents, (eggs, food vehicles using enlargement. May lead to focal chloramphenicol, typhymurium, S. rep-tiles [especially eggs, etc.). Human to infection in any organ or tissue of the neomycin, ampicillin Salmonellosis Bacteria typhi) turtles], chickens and human transmission also body) fish) and herd animals possible (cattle, chickens, pigs) All Shigella species Captive non-human Oral-fecal route Ranges from asymptomatic carrier to Varies by Highly infective. Low Intravenous fluids primates severe bacillary dysentery with high species. 16 number of organisms and electrolytes, fevers, weakness, severe abdominal hours to 7 capable of causing Antibiotics: ampicillin, cramps, prostration, edema of the days. -
Hepatitis B? HEPATITIS B Hepatitis B Is a Contagious Liver Disease That Results from Infection with the Hepatitis B Virus
What is Hepatitis B? HEPATITIS B Hepatitis B is a contagious liver disease that results from infection with the Hepatitis B virus. When first infected, a person can develop Are you at risk? an “acute” infection, which can range in severity from a very mild illness with few or no symptoms to a serious condition requiring hospitalization. Acute Hepatitis B refers to the first 6 months after someone is exposed to the Hepatitis B virus. Some people are able to fight the infection and clear the virus. For others, the infection remains and leads to a “chronic,” or lifelong, illness. Chronic Hepatitis B refers to the illness that occurs when the Hepatitis B virus remains in a person’s body. Over time, the infection can cause serious health problems. How is Hepatitis B spread? Hepatitis B is usually spread when blood, semen, or other body fluids from a person infected with the Hepatitis B virus enter the body of someone who is not infected. This can happen through having sex with an infected partner; sharing needles, syringes, or other injection drug equipment; or from direct contact with the blood or open sores of an infected person. Hepatitis B can also be passed from an infected mother to her baby at birth. Who should be tested for Hepatitis B? Approximately 1.2 million people in the United States and 350 million people worldwide have Hepatitis B. Testing for Hepatitis B is recommended for certain groups of people, including: Most are unaware of their infection. ■ People born in Asia, Africa, and other regions with moderate or high rates Is Hepatitis B common? of Hepatitis B (see map) Yes. -
Hepatitis A, B, and C: Learn the Differences
Hepatitis A, B, and C: Learn the Differences Hepatitis A Hepatitis B Hepatitis C caused by the hepatitis A virus (HAV) caused by the hepatitis B virus (HBV) caused by the hepatitis C virus (HCV) HAV is found in the feces (poop) of people with hepa- HBV is found in blood and certain body fluids. The virus is spread HCV is found in blood and certain body fluids. The titis A and is usually spread by close personal contact when blood or body fluid from an infected person enters the body virus is spread when blood or body fluid from an HCV- (including sex or living in the same household). It of a person who is not immune. HBV is spread through having infected person enters another person’s body. HCV can also be spread by eating food or drinking water unprotected sex with an infected person, sharing needles or is spread through sharing needles or “works” when contaminated with HAV. “works” when shooting drugs, exposure to needlesticks or sharps shooting drugs, through exposure to needlesticks on the job, or from an infected mother to her baby during birth. or sharps on the job, or sometimes from an infected How is it spread? Exposure to infected blood in ANY situation can be a risk for mother to her baby during birth. It is possible to trans- transmission. mit HCV during sex, but it is not common. • People who wish to be protected from HAV infection • All infants, children, and teens ages 0 through 18 years There is no vaccine to prevent HCV.