March 2009 Newsletter
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REVIEW Signal Transduction, Cell Cycle Regulatory, and Anti
Leukemia (1999) 13, 1109–1166 1999 Stockton Press All rights reserved 0887-6924/99 $12.00 http://www.stockton-press.co.uk/leu REVIEW Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs WL Blalock1, C Weinstein-Oppenheimer1,2, F Chang1, PE Hoyle1, X-Y Wang3, PA Algate4, RA Franklin1,5, SM Oberhaus1,5, LS Steelman1 and JA McCubrey1,5 1Department of Microbiology and Immunology, 5Leo Jenkins Cancer Center, East Carolina University School of Medicine Greenville, NC, USA; 2Escuela de Quı´mica y Farmacia, Facultad de Medicina, Universidad de Valparaiso, Valparaiso, Chile; 3Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, MN, USA; and 4Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Over the past decade, there has been an exponential increase growth factor), Flt-L (the ligand for the flt2/3 receptor), erythro- in our knowledge of how cytokines regulate signal transduc- poietin (EPO), and others affect the growth and differentiation tion, cell cycle progression, differentiation and apoptosis. Research has focused on different biochemical and genetic of these early hematopoietic precursor cells into cells of the 1–4 aspects of these processes. Initially, cytokines were identified myeloid, lymphoid and erythroid lineages (Table 1). This by clonogenic assays and purified by biochemical techniques. review will concentrate on IL-3 since much of the knowledge This soon led to the molecular cloning of the genes encoding of how cytokines affect cell growth, signal transduction, and the cytokines and their cognate receptors. -
Glossary Glossary
Glossary Glossary Albedo A measure of an object’s reflectivity. A pure white reflecting surface has an albedo of 1.0 (100%). A pitch-black, nonreflecting surface has an albedo of 0.0. The Moon is a fairly dark object with a combined albedo of 0.07 (reflecting 7% of the sunlight that falls upon it). The albedo range of the lunar maria is between 0.05 and 0.08. The brighter highlands have an albedo range from 0.09 to 0.15. Anorthosite Rocks rich in the mineral feldspar, making up much of the Moon’s bright highland regions. Aperture The diameter of a telescope’s objective lens or primary mirror. Apogee The point in the Moon’s orbit where it is furthest from the Earth. At apogee, the Moon can reach a maximum distance of 406,700 km from the Earth. Apollo The manned lunar program of the United States. Between July 1969 and December 1972, six Apollo missions landed on the Moon, allowing a total of 12 astronauts to explore its surface. Asteroid A minor planet. A large solid body of rock in orbit around the Sun. Banded crater A crater that displays dusky linear tracts on its inner walls and/or floor. 250 Basalt A dark, fine-grained volcanic rock, low in silicon, with a low viscosity. Basaltic material fills many of the Moon’s major basins, especially on the near side. Glossary Basin A very large circular impact structure (usually comprising multiple concentric rings) that usually displays some degree of flooding with lava. The largest and most conspicuous lava- flooded basins on the Moon are found on the near side, and most are filled to their outer edges with mare basalts. -
DEKLIM a German Contribution to the IGBP-PAGES Program
PAGES International Project Offi ce Sulgeneckstrasse 38 3007 Bern Switzerland Tel: +41 31 312 31 33 Fax: +41 31 312 31 68 [email protected] Text Editing: Leah Christen News Layout: Christoph Kull Frank Sirocko and Gerrit Lohmann, Guest Editors Circulation: 3400 Christoph Kull and Leah Christen, Editors VOL.12, N°2 – SEPTEMBER 2004 DEKLIM A German Contribution to the IGBP-PAGES Program www.pages-igbp.org Grouping of the 33 DEKLIM-Paleo projects into 13 bundles: This special issue presents results as well as working reports of the ongoing program. A DEKLIM overview is presented in the “Program News” section. Contents 2 Announcements - Climate Change around 117 ka BP - Editorial: DEKLIM Paleo - Climate Transitions: Forcings - Feedbacks - Inside PAGES - Tree Rings, Isotopes and Climate - New on the PAGES Bookshelf - Modeling the Last Glacial Cycle - Global Holocene Climate Variability 4 Program News - Late Glacial Changes in Central Europe - PROPER: Proxies in Paleoclimatology - The Global Carbon Cycle around 20 ka BP - Paleocat: A Catalan Paleo-Network - North Atlantic Coral Climate History - DEKLIM: German Climate Research 33 Workshop Reports 8 National Page - Holocene Climate in the Alps - France - Ethiopia - Holocene Monsoon Variability - India - African Paleoenvironments - Kenya 9 Science Highlights - Climate Change in Southern Patagonia 36 Last Page - Modeling the Atmospheric Circulation - Calendar - Solar Variability and Holocene Climate - The PAGES Product Database - 18O/16O Ratio during Heinrich Event 1 ISSN 1563–0803 The PAGES International Project Offi ce and its publications are supported by the Swiss and US National Science Foundations and NOAA. 2 Announcements Announcements 3 Editorial: DEKLIM - PALEO The results of climate research enjoy a high level of public interest. -
Bingo Carpet
V -A - PAGE TWENTY ■\ THURSDAY, JULY 17, 1969 AYwage Daily Net Press Run lEtiptttng ilf r a li Far The Week Ended June 28. 1666& The Weather les, Simsbury and Evelyn Rob R ockville erts. Prospect St,, Rockville.' Chance o4 scattered thunder Dlschagred Tuesday: Dale PJV.C. 15,459 showers toward evening, ’IV> Hospital Notes Schenk, Mt. Vernon Dr., Rock night cloudy, decreasing hu ville; Frank Mlffltt, Rockville; midity. Low 85 to TO. ’Tbtnor- Visltlniir hours are 12;S0 to 8 Thomas Lee, Franklin Park. MancheMer— 4 City of Village Charm row cloudy, idiowers likely. p.m. in all areas except mater Rockville; i Oliver Johnston, VOL, LXXXVm. MO, 2<5 (TWENTY-POUR PAGES-TWO SECTIONS) nity where they are 2 to 4 and Rockville; Katheryn Pippin, MANCHESTER, CONN., FRIDAY, JULY 18, 1969 6:30 to 8 p.m . ''' (Claaslfled Advertlstiig on Page 20) Broad Brook; B arbara Olen- I ~ ~ ^ ------- ------------ ^-------- PRICE TEN CENTS der, Gehring Rd., Tolland; Admitted Tuesday: Patricia* BINGO Louis Lavltt, Hillsdale Dr., Fournier, Cook Rd., Tolland; EVERY MONDAY-E P.M. Rockville; BMlen Gunther, Rock A Donald Johnson, Rock^lle; ville; Robertha H a^s, Rock 26 VILLAGE STREET, ROCKVILLE Apollo TV Schedule George Allen, Rt. 2, Tolland; ville, and Kathleen Duval, Vil P. A. C. BALLROOM NEW YORK (AP)—F^low- Vernon ;n-ald lage St,, RockvHle. Scott Tetro, Broad Brook; Mar Honduras Charges ing are the television s^ed- jorie Nelson, Tankerhoosan ules of major networiu for A liquor company In Peoria. Apollo 11 coverage; Birth Control Advice Rd., Vernon; John Bemache, 111., produces up to 1,500,000 bot ThompsonvlUe; Josephine Rob Read Herald Advertisements BMday : Live color trans- tles of liquor a day. -
Transportation Committee Thursday, May 2, 2013, at 10:00 A.M
Sacramento Area 1415 L Street, tel: 916.321.9000 Council of Suite 300 fax: 916.321.9551 Sacramento, CA tdd: 916.321.9550 Governments 95814 www.sacog.org Transportation Committee Thursday, May 2, 2013, at 10:00 a.m. Roll Call: Directors Cabaldon, Cohn, Crews (non-voting), Griego, Hesch, Hodges, Holmes (alternate), Joiner, Ex-officio Member Jones, Krovoza, Peters, Slowey, Vice Chairs Hagen and Sander, and Chair Saylor Public Communications: Any person wishing to address the committee on any item not on the agenda may do so at this time. After ten minutes of testimony, any additional testimony will be heard following the action items. 1. Minutes of the April 4, 2013, Meeting◄ (Mr. Carpenter) 2. Funding of Transit Projects Using Federal Transit Administration Section 5307 and 5339 FFY 2013 Apportionments to the Sacramento Urbanized Area◄ (Mr. Taylor) 3. Flexible Funds Programing Round Framework and Application Process◄ Ms. DeVere-Oki 4. Regional Bicycle, Pedestrian, and Trails Master Plan Update◄ (Ms. Cacciatore) 5. Transportation Investment Generating Economic Recovery (TIGER) V Nomination Process◄ (Ms. DeVere-Oki) 6. Fiscal Year 2013-14 Provisional Budget for the Capitol Valley Regional Service Authority for Freeways and Expressways (CVRS)◄ (Mr. Heiman) 7. Call Box Maintenance Request for Proposals Release◄ (Mr. Heiman) 8. SACOG Toll Credits Policy◄ (Mr. Carpenter/Ms. Arnold) 9. Background Briefing on Blueprint and Metropolitan Transportation Plan/Sustainable Communities Strategy 2035 (Mr. McKeever) 10. May Is Bike Month 2012 Recap and 2013 Campaign Update (Mr. Tendick) 11. Transportation Committee Planning Calendar Update (Mr. Carpenter) 12. Other Matters 13. Adjournment ◄ Indicates Action Prepared by: Approved by: Mike McKeever Don Saylor Chief Executive Officer Chair Next committee meeting: Thursday, June 6, 2013 The Meridian Plaza Building is accessible to the disabled. -
ICD-9 Diagnosis Codes Effective 10/1/2011 (V29.0) Source: Centers for Medicare and Medicaid Services
ICD-9 Diagnosis Codes effective 10/1/2011 (v29.0) Source: Centers for Medicare and Medicaid Services 0010 Cholera d/t vib cholerae 00801 Int inf e coli entrpath 01086 Prim prg TB NEC-oth test 0011 Cholera d/t vib el tor 00802 Int inf e coli entrtoxgn 01090 Primary TB NOS-unspec 0019 Cholera NOS 00803 Int inf e coli entrnvsv 01091 Primary TB NOS-no exam 0020 Typhoid fever 00804 Int inf e coli entrhmrg 01092 Primary TB NOS-exam unkn 0021 Paratyphoid fever a 00809 Int inf e coli spcf NEC 01093 Primary TB NOS-micro dx 0022 Paratyphoid fever b 0081 Arizona enteritis 01094 Primary TB NOS-cult dx 0023 Paratyphoid fever c 0082 Aerobacter enteritis 01095 Primary TB NOS-histo dx 0029 Paratyphoid fever NOS 0083 Proteus enteritis 01096 Primary TB NOS-oth test 0030 Salmonella enteritis 00841 Staphylococc enteritis 01100 TB lung infiltr-unspec 0031 Salmonella septicemia 00842 Pseudomonas enteritis 01101 TB lung infiltr-no exam 00320 Local salmonella inf NOS 00843 Int infec campylobacter 01102 TB lung infiltr-exm unkn 00321 Salmonella meningitis 00844 Int inf yrsnia entrcltca 01103 TB lung infiltr-micro dx 00322 Salmonella pneumonia 00845 Int inf clstrdium dfcile 01104 TB lung infiltr-cult dx 00323 Salmonella arthritis 00846 Intes infec oth anerobes 01105 TB lung infiltr-histo dx 00324 Salmonella osteomyelitis 00847 Int inf oth grm neg bctr 01106 TB lung infiltr-oth test 00329 Local salmonella inf NEC 00849 Bacterial enteritis NEC 01110 TB lung nodular-unspec 0038 Salmonella infection NEC 0085 Bacterial enteritis NOS 01111 TB lung nodular-no exam 0039 -
Sky and Telescope
SkyandTelescope.com The Lunar 100 By Charles A. Wood Just about every telescope user is familiar with French comet hunter Charles Messier's catalog of fuzzy objects. Messier's 18th-century listing of 109 galaxies, clusters, and nebulae contains some of the largest, brightest, and most visually interesting deep-sky treasures visible from the Northern Hemisphere. Little wonder that observing all the M objects is regarded as a virtual rite of passage for amateur astronomers. But the night sky offers an object that is larger, brighter, and more visually captivating than anything on Messier's list: the Moon. Yet many backyard astronomers never go beyond the astro-tourist stage to acquire the knowledge and understanding necessary to really appreciate what they're looking at, and how magnificent and amazing it truly is. Perhaps this is because after they identify a few of the Moon's most conspicuous features, many amateurs don't know where Many Lunar 100 selections are plainly visible in this image of the full Moon, while others require to look next. a more detailed view, different illumination, or favorable libration. North is up. S&T: Gary The Lunar 100 list is an attempt to provide Moon lovers with Seronik something akin to what deep-sky observers enjoy with the Messier catalog: a selection of telescopic sights to ignite interest and enhance understanding. Presented here is a selection of the Moon's 100 most interesting regions, craters, basins, mountains, rilles, and domes. I challenge observers to find and observe them all and, more important, to consider what each feature tells us about lunar and Earth history. -
Guide to the Identification of Precious and Semi-Precious Corals in Commercial Trade
'l'llA FFIC YvALE ,.._,..---...- guide to the identification of precious and semi-precious corals in commercial trade Ernest W.T. Cooper, Susan J. Torntore, Angela S.M. Leung, Tanya Shadbolt and Carolyn Dawe September 2011 © 2011 World Wildlife Fund and TRAFFIC. All rights reserved. ISBN 978-0-9693730-3-2 Reproduction and distribution for resale by any means photographic or mechanical, including photocopying, recording, taping or information storage and retrieval systems of any parts of this book, illustrations or texts is prohibited without prior written consent from World Wildlife Fund (WWF). Reproduction for CITES enforcement or educational and other non-commercial purposes by CITES Authorities and the CITES Secretariat is authorized without prior written permission, provided the source is fully acknowledged. Any reproduction, in full or in part, of this publication must credit WWF and TRAFFIC North America. The views of the authors expressed in this publication do not necessarily reflect those of the TRAFFIC network, WWF, or the International Union for Conservation of Nature (IUCN). The designation of geographical entities in this publication and the presentation of the material do not imply the expression of any opinion whatsoever on the part of WWF, TRAFFIC, or IUCN concerning the legal status of any country, territory, or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. The TRAFFIC symbol copyright and Registered Trademark ownership are held by WWF. TRAFFIC is a joint program of WWF and IUCN. Suggested citation: Cooper, E.W.T., Torntore, S.J., Leung, A.S.M, Shadbolt, T. and Dawe, C. -
August 2017 Posidonius P & Luther
A PUBLICATION OF THE LUNAR SECTION OF THE A.L.P.O. EDITED BY: Wayne Bailey [email protected] 17 Autumn Lane, Sewell, NJ 08080 RECENT BACK ISSUES: http://moon.scopesandscapes.com/tlo_back.html FEATURE OF THE MONTH – AUGUST 2017 POSIDONIUS P & LUTHER Sketch and text by Robert H. Hays, Jr. - Worth, Illinois, USA March 5, 2017 01:28-01:48; UT, 15 cm refl, 170x, seeing 7-8/10. I drew these craters on the evening of March 4/5, 2017 while the moon was hiding some Hyades stars. This area is in northeast Mare Serenitatis west of Posidonius itself. Posidonius P is the largest crater on this sketch. The smaller crater south of P is Posidonius F and Posidonius G is the tiny pit to the north. There is a halo around Posidonius G, but this crater is noticeably north of the halo's center. A very low round swelling is northeast of Posidonius G. Luther is the crater well to the west of Posidonius P. All four of these craters are crisp, symmetric features, differing only in size. There are an assortment of elevations near Luther. The peak Luther alpha is well to the west of Luther, and showed dark shadowing at this time. All of the other features near Luther are more subtle than Luther alpha. One mound is between Luther and Luther alpha. Two more mounds are north of Luther, and a low ridge is just east of this crater. A pair of very low mounds are south of Luther. These are the vaguest features depicted here, and may be too conspicuous on the sketch. -
Publications Supported by NOAA's Office of Ocean Exploration And
1 Publications Supported by NOAA’s Office of Ocean Exploration and Research Compiled by Chris Belter, NOAA Central Library Accurate as of 17 April 2012 Journal Articles (n=454) Ahyong ST. 2008. Deepwater crabs from seamounts and chemosynthetic habitats off eastern New Zealand (Crustacea : Decapoda : Brachyura). Zootaxa(1708):1-72. Aig D, Haywood K. 2008. Through the Sea Snow: The Central Role of Videography in the Deep Gulf Wrecks Mission. International Journal of Historical Archaeology 12(2):133-145. doi:10.1007/s10761-008-0049-7 Andrews AH, Stone RP, Lundstrom CC, DeVogelaere AP. 2009. Growth rate and age determination of bamboo corals from the northeastern Pacific Ocean using refined Pb-210 dating. Marine Ecology-Progress Series 397:173-185. doi:10.3354/meps08193 Angel MV. 2010. Towards a full inventory of planktonic Ostracoda (Crustacea) for the subtropical Northwestern Atlantic Ocean. Deep-Sea Research Part Ii-Topical Studies in Oceanography 57(24-26):2173-2188. doi:10.1016/j.dsr2.2010.09.020 Arellano SM, Young CM. 2009. Spawning, Development, and the Duration of Larval Life in a Deep-Sea Cold-Seep Mussel. Biological Bulletin 216(2):149-162. Auster PJ. 2007. Linking deep-water corals and fish populations. Bulletin of Marine Science 81:93-99. Auster PJ, Gjerde K, Heupel E, Watling L, Grehan A, Rogers AD. 2011. Definition and detection of vulnerable marine ecosystems on the high seas: problems with the "move-on" rule. ICES Journal of Marine Science 68(2):254-264. doi:10.1093/icesjms/fsq074 Auster PJ, Watling L. 2010. Beaked whale foraging areas inferred by gouges in the seafloor. -
List of Targets for the Lunar II Observing Program (PDF File)
Task or Task Description or Target Name Wood's Rükl Target LUNAR # 100 Atlas Catalog (chart) Create a sketch/map of the visible lunar surface: 1 Observe a Full Moon and sketch a large-scale (prominent features) L-1 map depicting the nearside; disk of visible surface should be drawn 2 at L-1 3 least 5-inches in diameter. Sketch itself should be created only by L-1 observing the Moon, but maps or guidebooks may be used when labeling sketched features. Label all maria, prominent craters, and major rays by the crater name they originated from. (Counts as 3 observations (OBSV): #1, #2 & #3) Observe these targets; provide brief descriptions: 4 Alpetragius 55 5 Arago 35 6 Arago Alpha & Arago Beta L-32 35 7 Aristarchus Plateau L-18 18 8 Baco L-55 74 9 Bailly L-37 71 10 Beer, Beer Catena & Feuillée 21 11 Bullialdus, Bullialdus A & Bullialdus B 53 12 Cassini, Cassini A & Cassini B 12 13 Cauchy, Cauchy Omega & Cauchy Tau L-48 36 14 Censorinus 47 15 Crüger 50 16 Dorsae Lister & Smirnov (A.K.A. Serpentine Ridge) L-33 24 17 Grimaldi Basin outer and inner rings L-36 39, etc. 18 Hainzel, Hainzel A & Hainzel C 63 19 Hercules, Hercules G, Hercules E 14 20 Hesiodus A L-81 54, 64 21 Hortensius dome field L-65 30 22 Julius Caesar 34 23 Kies 53 24 Kies Pi L-60 53 25 Lacus Mortis 14 26 Linne 23 27 Lamont L-53 35 28 Mairan 9 29 Mare Australe L-56 76 30 Mare Cognitum 42, etc. -
2017 Chicxulub Revealed
THE UNIVERSITY TEXAS OF AUSTIN AT JACKSON• SCHOOL GEOSCIENCES OF 2017 NEWSLETTER• Newsletter2 017 Chicxulub Revealed A first look at rocks from the crater left by the asteroid that wiped out non-avian dinosaurs WELCOME Dear Alumni and Friends he devastation that Hurricane Harvey brought to Texas communities in August was a tragic reminder of how vital it is to understand our planet and T its processes. Shortly after the hurricane struck, our scientists, through our Rapid Response program, began to conduct research to understand how Harvey has impacted the coast and offshore Gulf of Mexico. This research will help determine the best ways to deal with many coastal issues in the aftermath of the storm, and how we might better prepare for such events in the future. You can read more about the mission on page 18. Rapid response efforts on the effects of abrupt, catastrophic geoscience events COVER: GRANITE FROM THE PEAK RING OF provide critical science that can benefit society. This is what we strive to do here at the THE CHICXULUB CRATER FORMED BY THE Jackson School of Geosciences. This year’s Newsletter holds some tremendous examples. ASTEROID STRIKE THAT WIPED OUT ALL NON- AVIAN DINOSAURS I’d like to draw your attention to the story on page 58 about the scientific coring mission led by Peter Flemings to bring back samples of methane hydrate from ABOVE: MEMBERS OF THE JACKSON beneath the Gulf of Mexico. This is a cutting-edge research project on a potential SCHOOL-LED TEAM CORING FOR SAMPLES OF METHANE HYDRATE IN THE GULF OF MEXICO future energy source that very few schools in the world would be able to mount.