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REVIEW Signal Transduction, Cell Cycle Regulatory, and Anti
Leukemia (1999) 13, 1109–1166 1999 Stockton Press All rights reserved 0887-6924/99 $12.00 http://www.stockton-press.co.uk/leu REVIEW Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs WL Blalock1, C Weinstein-Oppenheimer1,2, F Chang1, PE Hoyle1, X-Y Wang3, PA Algate4, RA Franklin1,5, SM Oberhaus1,5, LS Steelman1 and JA McCubrey1,5 1Department of Microbiology and Immunology, 5Leo Jenkins Cancer Center, East Carolina University School of Medicine Greenville, NC, USA; 2Escuela de Quı´mica y Farmacia, Facultad de Medicina, Universidad de Valparaiso, Valparaiso, Chile; 3Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, MN, USA; and 4Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Over the past decade, there has been an exponential increase growth factor), Flt-L (the ligand for the flt2/3 receptor), erythro- in our knowledge of how cytokines regulate signal transduc- poietin (EPO), and others affect the growth and differentiation tion, cell cycle progression, differentiation and apoptosis. Research has focused on different biochemical and genetic of these early hematopoietic precursor cells into cells of the 1–4 aspects of these processes. Initially, cytokines were identified myeloid, lymphoid and erythroid lineages (Table 1). This by clonogenic assays and purified by biochemical techniques. review will concentrate on IL-3 since much of the knowledge This soon led to the molecular cloning of the genes encoding of how cytokines affect cell growth, signal transduction, and the cytokines and their cognate receptors. -
Bingo Carpet
V -A - PAGE TWENTY ■\ THURSDAY, JULY 17, 1969 AYwage Daily Net Press Run lEtiptttng ilf r a li Far The Week Ended June 28. 1666& The Weather les, Simsbury and Evelyn Rob R ockville erts. Prospect St,, Rockville.' Chance o4 scattered thunder Dlschagred Tuesday: Dale PJV.C. 15,459 showers toward evening, ’IV> Hospital Notes Schenk, Mt. Vernon Dr., Rock night cloudy, decreasing hu ville; Frank Mlffltt, Rockville; midity. Low 85 to TO. ’Tbtnor- Visltlniir hours are 12;S0 to 8 Thomas Lee, Franklin Park. MancheMer— 4 City of Village Charm row cloudy, idiowers likely. p.m. in all areas except mater Rockville; i Oliver Johnston, VOL, LXXXVm. MO, 2<5 (TWENTY-POUR PAGES-TWO SECTIONS) nity where they are 2 to 4 and Rockville; Katheryn Pippin, MANCHESTER, CONN., FRIDAY, JULY 18, 1969 6:30 to 8 p.m . ''' (Claaslfled Advertlstiig on Page 20) Broad Brook; B arbara Olen- I ~ ~ ^ ------- ------------ ^-------- PRICE TEN CENTS der, Gehring Rd., Tolland; Admitted Tuesday: Patricia* BINGO Louis Lavltt, Hillsdale Dr., Fournier, Cook Rd., Tolland; EVERY MONDAY-E P.M. Rockville; BMlen Gunther, Rock A Donald Johnson, Rock^lle; ville; Robertha H a^s, Rock 26 VILLAGE STREET, ROCKVILLE Apollo TV Schedule George Allen, Rt. 2, Tolland; ville, and Kathleen Duval, Vil P. A. C. BALLROOM NEW YORK (AP)—F^low- Vernon ;n-ald lage St,, RockvHle. Scott Tetro, Broad Brook; Mar Honduras Charges ing are the television s^ed- jorie Nelson, Tankerhoosan ules of major networiu for A liquor company In Peoria. Apollo 11 coverage; Birth Control Advice Rd., Vernon; John Bemache, 111., produces up to 1,500,000 bot ThompsonvlUe; Josephine Rob Read Herald Advertisements BMday : Live color trans- tles of liquor a day. -
ICD-9 Diagnosis Codes Effective 10/1/2011 (V29.0) Source: Centers for Medicare and Medicaid Services
ICD-9 Diagnosis Codes effective 10/1/2011 (v29.0) Source: Centers for Medicare and Medicaid Services 0010 Cholera d/t vib cholerae 00801 Int inf e coli entrpath 01086 Prim prg TB NEC-oth test 0011 Cholera d/t vib el tor 00802 Int inf e coli entrtoxgn 01090 Primary TB NOS-unspec 0019 Cholera NOS 00803 Int inf e coli entrnvsv 01091 Primary TB NOS-no exam 0020 Typhoid fever 00804 Int inf e coli entrhmrg 01092 Primary TB NOS-exam unkn 0021 Paratyphoid fever a 00809 Int inf e coli spcf NEC 01093 Primary TB NOS-micro dx 0022 Paratyphoid fever b 0081 Arizona enteritis 01094 Primary TB NOS-cult dx 0023 Paratyphoid fever c 0082 Aerobacter enteritis 01095 Primary TB NOS-histo dx 0029 Paratyphoid fever NOS 0083 Proteus enteritis 01096 Primary TB NOS-oth test 0030 Salmonella enteritis 00841 Staphylococc enteritis 01100 TB lung infiltr-unspec 0031 Salmonella septicemia 00842 Pseudomonas enteritis 01101 TB lung infiltr-no exam 00320 Local salmonella inf NOS 00843 Int infec campylobacter 01102 TB lung infiltr-exm unkn 00321 Salmonella meningitis 00844 Int inf yrsnia entrcltca 01103 TB lung infiltr-micro dx 00322 Salmonella pneumonia 00845 Int inf clstrdium dfcile 01104 TB lung infiltr-cult dx 00323 Salmonella arthritis 00846 Intes infec oth anerobes 01105 TB lung infiltr-histo dx 00324 Salmonella osteomyelitis 00847 Int inf oth grm neg bctr 01106 TB lung infiltr-oth test 00329 Local salmonella inf NEC 00849 Bacterial enteritis NEC 01110 TB lung nodular-unspec 0038 Salmonella infection NEC 0085 Bacterial enteritis NOS 01111 TB lung nodular-no exam 0039 -
2017 Chicxulub Revealed
THE UNIVERSITY TEXAS OF AUSTIN AT JACKSON• SCHOOL GEOSCIENCES OF 2017 NEWSLETTER• Newsletter2 017 Chicxulub Revealed A first look at rocks from the crater left by the asteroid that wiped out non-avian dinosaurs WELCOME Dear Alumni and Friends he devastation that Hurricane Harvey brought to Texas communities in August was a tragic reminder of how vital it is to understand our planet and T its processes. Shortly after the hurricane struck, our scientists, through our Rapid Response program, began to conduct research to understand how Harvey has impacted the coast and offshore Gulf of Mexico. This research will help determine the best ways to deal with many coastal issues in the aftermath of the storm, and how we might better prepare for such events in the future. You can read more about the mission on page 18. Rapid response efforts on the effects of abrupt, catastrophic geoscience events COVER: GRANITE FROM THE PEAK RING OF provide critical science that can benefit society. This is what we strive to do here at the THE CHICXULUB CRATER FORMED BY THE Jackson School of Geosciences. This year’s Newsletter holds some tremendous examples. ASTEROID STRIKE THAT WIPED OUT ALL NON- AVIAN DINOSAURS I’d like to draw your attention to the story on page 58 about the scientific coring mission led by Peter Flemings to bring back samples of methane hydrate from ABOVE: MEMBERS OF THE JACKSON beneath the Gulf of Mexico. This is a cutting-edge research project on a potential SCHOOL-LED TEAM CORING FOR SAMPLES OF METHANE HYDRATE IN THE GULF OF MEXICO future energy source that very few schools in the world would be able to mount. -
Summary of Sexual Abuse Claims in Chapter 11 Cases of Boy Scouts of America
Summary of Sexual Abuse Claims in Chapter 11 Cases of Boy Scouts of America There are approximately 101,135sexual abuse claims filed. Of those claims, the Tort Claimants’ Committee estimates that there are approximately 83,807 unique claims if the amended and superseded and multiple claims filed on account of the same survivor are removed. The summary of sexual abuse claims below uses the set of 83,807 of claim for purposes of claims summary below.1 The Tort Claimants’ Committee has broken down the sexual abuse claims in various categories for the purpose of disclosing where and when the sexual abuse claims arose and the identity of certain of the parties that are implicated in the alleged sexual abuse. Attached hereto as Exhibit 1 is a chart that shows the sexual abuse claims broken down by the year in which they first arose. Please note that there approximately 10,500 claims did not provide a date for when the sexual abuse occurred. As a result, those claims have not been assigned a year in which the abuse first arose. Attached hereto as Exhibit 2 is a chart that shows the claims broken down by the state or jurisdiction in which they arose. Please note there are approximately 7,186 claims that did not provide a location of abuse. Those claims are reflected by YY or ZZ in the codes used to identify the applicable state or jurisdiction. Those claims have not been assigned a state or other jurisdiction. Attached hereto as Exhibit 3 is a chart that shows the claims broken down by the Local Council implicated in the sexual abuse. -
March 2009 Newsletter
www.spnhc.org President Richard Rabeler President-Elect Jean-Marc Gagnon Past President Tim White Treasurer Barbara Brown Society for the Preservation March 2009 Secretary Volume 23, Number 1 Judith Price of Natural History Collections Managing Editor Jean F. DeMouthe Editor Scientific Collections: Mission-Critical Andrew C. Bentley Infrastructure for Federal Service Agencies Executive Summary from the report of the Interagency Working Group on Scientific Collections (IWGSC) Beginning in 2005, the White House Office of and human resources. Scientific collections, Science and Technology Policy (OSTP) and as discussed in this report, consist of physi- Office of Management and Budget (OMB) cal objects that are preserved, cataloged, and called on Federal agencies to focus attention managed by Federal agencies and other or- on integrated support and planning for their ganizations for research and other purposes. care and use of Federally held scientific col- Scientific collections do not include art or his- lections. Based in part on these recommen- torical objects, collectibles, or the books and dations, an Interagency Working Group on documents that are stored in libraries and ar- INSIDE... Scientific Collections (IWGSC) was created, chives. The specimens in scientific collections co-chaired by representatives of the were acquired as objects for scientific study, Scientific Collections .. 1 Smithsonian Institution (SI) and the U.S. not for their aesthetic or market value as col- Presidential Report ..... 3 Department of Agriculture (USDA) to exam- lectibles. In general, the contents of these sci- Committee Reports..... 4 ine the current state of Federal scientific col- entific collections are documented and publi- Sessional Committee lections and to make recommendations for cized with the goal of making the specimens reports .................... -
Et Mail Front Mexico Hints a T Icmocket Total
■ v'., : • ':■■ I* ^AOE rOURTEEN TUESDAY* KOVEBfBER 17,1989 Average Dally Net Ptcm Ron ifiatirlrf^pr lEofnhtg F ar Om Weak IM ae Tilt Weather N*4r. M. lese ! «r V. A waeaam . Center' Church Motheri'- Club plana calling for :only bna upatatra of 232 Spring SL which 'would be than regulations allow. The prop AboiilTciwii tl-iu mpet In the Federation room ^ B A D enies apartmant inauad of the formarly Closer to the street line than reg erty Li located east of 1768 Tol-. 13,041 'I tomoh-ow at 8 p'.m. Miaa M argaret propoaed two-in the building, were ulation* allow. Former Police land 'Tpke. T f l L f . Laar lAW . Parker M Children'* Service* udll submitted last-night. Atty. John D. Chief Herman ; O, Schendel and Tabled'sfas ,* request lor ah ex M anbar ^ WfiT AM H ' XI Ounm» dhapter of Beta SiR- hfe guest speaker. Refreshments Ware Bid to LsBelle repraschted the appllcsnt.. Atty^ Donald Richter qtoke In op tension of permiasidn eought by meftiu B m m irw f Otrewhrtiaa. Kc Wil will meet !> o’clock to- will be 'servrt, ^ In other action, tha toners ap position. Atty. LaBelle represent Samuel Lombkrdo to maintain a ManchmttBr"^A City of ViUoge Charm iam- mgk iHMMe to wnwr Ms. n llk t a t tka Tiome ot^Mra. Jamer '* , * ■ i proved a variance -request from ed the applicant. building, for storage and shelter FUchmend. ^4T Btimmlt St. , St. Anne's Mothers' Circle’ wilt Pack Chutes Dr. Robert. C. Walden Jr., 102 The board dented a request froth for a watchman on the east side : Find It At. -
Cong Sounds Peace Overture
■ < V'; The Weather Kaak First-Day Open Leader Fair tonight. Low 50 to 55, chance - of rain 10 per cent. Goudy Page 16 lEuf mnn I Tuesday with a 30 per cent V chance of showers; hl^ in the .low 80s. MANCHESTER — 4 City o f Village Charm TWENTY-TWO PAGES MANCHESTER, CONN., MONDAY, SEPTEMBER 11,19^2 VOL. XCI. No. 291 PRICE FIFTEEN CENTS Students Take Cong Sounds ^Strike’ Recess tj Over Nation Peace Overture previous formula for the makeup By THE ASSOaATED PRESS SAIGON (AP) - The Viet Once again it called on the of the government of national Cong issued a new peace United States to withdraw all its Negotiations remained deadlocked today in the concord—a three-segment coali statement today saying it is troops from Vietnam, to stop Philadelphia teachers strike, but Kansas City youngsters supporting the regime of Presi tion composed of (1) members of "prepared to accept a were back in class and there were signs of progress in several dent Nguyen Van Thieu, and to the Provisional Revolutionary other school walkouts across the country. - ^ provisional government of halt the bombing and mining of Government, (2) members of the national concord that shall be Saigon administration excluding Spokesmen for both the P'riday because custodians and North Vietnam. dominated by neither side." Thieu, and (3) representatives of teachers' union and the maintenance workers were on U.S, sources In Saigon inter " Should the U.S. government other political forces in South Philadelphia School Board ex strike and trash had accumulated preted this as a concession that really respect the South Viet Vietnam ""including those who, pressed doubt Sunday that the at the schools. -
Exemplar Texts for Grades
COMMON CORE STATE STANDARDS FOR English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects _____ Appendix B: Text Exemplars and Sample Performance Tasks OREGON COMMON CORE STATE STANDARDS FOR English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects Exemplars of Reading Text Complexity, Quality, and Range & Sample Performance Tasks Related to Core Standards Selecting Text Exemplars The following text samples primarily serve to exemplify the level of complexity and quality that the Standards require all students in a given grade band to engage with. Additionally, they are suggestive of the breadth of texts that students should encounter in the text types required by the Standards. The choices should serve as useful guideposts in helping educators select texts of similar complexity, quality, and range for their own classrooms. They expressly do not represent a partial or complete reading list. The process of text selection was guided by the following criteria: Complexity. Appendix A describes in detail a three-part model of measuring text complexity based on qualitative and quantitative indices of inherent text difficulty balanced with educators’ professional judgment in matching readers and texts in light of particular tasks. In selecting texts to serve as exemplars, the work group began by soliciting contributions from teachers, educational leaders, and researchers who have experience working with students in the grades for which the texts have been selected. These contributors were asked to recommend texts that they or their colleagues have used successfully with students in a given grade band. The work group made final selections based in part on whether qualitative and quantitative measures indicated that the recommended texts were of sufficient complexity for the grade band. -
The Planetary Turn
The Planetary Turn The Planetary Turn Relationality and Geoaesthetics in the Twenty- First Century Edited by Amy J. Elias and Christian Moraru northwestern university press evanston, illinois Northwestern University Press www .nupress.northwestern .edu Copyright © 2015 by Northwestern University Press. Published 2015. All rights reserved. Printed in the United States of America 10 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging- in- Publication Data The planetary turn : relationality and geoaesthetics in the twenty-first century / edited by Amy J. Elias and Christian Moraru. pages cm Includes bibliographical references. ISBN 978-0-8101-3073-9 (cloth : alk. paper) — ISBN 978-0-8101-3075-3 (pbk. : alk. paper) — ISBN 978-0-8101-3074-6 (ebook) 1. Space and time in literature. 2. Space and time in motion pictures. 3. Globalization in literature. 4. Aesthetics. I. Elias, Amy J., 1961– editor of compilation. II. Moraru, Christian, editor of compilation. PN56.S667P57 2015 809.9338—dc23 2014042757 Except where otherwise noted, this book is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. In all cases attribution should include the following information: Elias, Amy J., and Christian Moraru. The Planetary Turn: Relationality and Geoaesthetics in the Twenty-First Century. Evanston: Northwestern University Press, 2015. The following material is excluded from the license: Illustrations and an earlier version of “Gilgamesh’s Planetary Turns” by Wai Chee Dimock as outlined in the acknowledgments. For permissions beyond the scope of this license, visit http://www.nupress .northwestern.edu/. -
Cambridge University Press 978-1-107-15445-2 — Mercury Edited by Sean C
Cambridge University Press 978-1-107-15445-2 — Mercury Edited by Sean C. Solomon , Larry R. Nittler , Brian J. Anderson Index More Information INDEX 253 Mathilde, 196 BepiColombo, 46, 109, 134, 136, 138, 279, 314, 315, 366, 403, 463, 2P/Encke, 392 487, 488, 535, 544, 546, 547, 548–562, 563, 564, 565 4 Vesta, 195, 196, 350 BELA. See BepiColombo: BepiColombo Laser Altimeter 433 Eros, 195, 196, 339 BepiColombo Laser Altimeter, 554, 557, 558 gravity assists, 555 activation energy, 409, 412 gyroscope, 556 adiabat, 38 HGA. See BepiColombo: high-gain antenna adiabatic decompression melting, 38, 60, 168, 186 high-gain antenna, 556, 560 adiabatic gradient, 96 ISA. See BepiColombo: Italian Spring Accelerometer admittance, 64, 65, 74, 271 Italian Spring Accelerometer, 549, 554, 557, 558 aerodynamic fractionation, 507, 509 Magnetospheric Orbiter Sunshield and Interface, 552, 553, 555, 560 Airy isostasy, 64 MDM. See BepiColombo: Mercury Dust Monitor Al. See aluminum Mercury Dust Monitor, 554, 560–561 Al exosphere. See aluminum exosphere Mercury flybys, 555 albedo, 192, 198 Mercury Gamma-ray and Neutron Spectrometer, 554, 558 compared with other bodies, 196 Mercury Imaging X-ray Spectrometer, 558 Alfvén Mach number, 430, 433, 442, 463 Mercury Magnetospheric Orbiter, 552, 553, 554, 555, 556, 557, aluminum, 36, 38, 147, 177, 178–184, 185, 186, 209, 559–561 210 Mercury Orbiter Radio Science Experiment, 554, 556–558 aluminum exosphere, 371, 399–400, 403, 423–424 Mercury Planetary Orbiter, 366, 549, 550, 551, 552, 553, 554, 555, ground-based observations, 423 556–559, 560, 562 andesite, 179, 182, 183 Mercury Plasma Particle Experiment, 554, 561 Andrade creep function, 100 Mercury Sodium Atmospheric Spectral Imager, 554, 561 Andrade rheological model, 100 Mercury Thermal Infrared Spectrometer, 366, 554, 557–558 anorthosite, 30, 210 Mercury Transfer Module, 552, 553, 555, 561–562 anticline, 70, 251 MERTIS. -
Ellsworth American, a Newspaper Printea It Was Voted That the Road 1 the Leading from Under Him
■ ■ UBSCBIPTION American. PRIOB, $2.00 P» TIAB. LXV. IP PAID IN Vol. ADTANCB, $1.60. <EUstoortl| ELLSWORTH, MAINE, WEDNESDAY AFTERNOON, AUGUST 6, 1919. tfn 39. LOCAL AFFAIRS 'vv‘™ ■1 * >1 ovtrBeHs, Hmi recently aoumisrments. returned from France. nkw BURRILL aiivkktiskmknts this week The NATIONAL BANK body of Mrs. Hattie K. Jordan, who J A Haynes—Grocer died at Kenduskeag Monday, was brought here ELLSWORTH, MAINE Wood land and farm for sale to-day for interment. She was the Overland car wife touring for sale of Samuel P. Jordan, formerly of Notice of foreclosure—George A Arejr Ellsworth. She was forty-three years of The age. Banking Methods of SCHEDULE OP MAILS To-day Miss Mary Murphy, aged AT ELLSWORTH POSTOFFICE. twenty-four are while based upon the years, at the power station this principles re- In effect, June 30, 1919. and afternoon, came in contact with one of organized applied in the the high tension wires operation MAILS RKCUITBD. in the transformer of the room, burns from Federal Reserve Week Days.* receiving which it is Our embraces System. You From feared she not equipment every modern fa- West-7.00, 7.18, 11.60 a m; 4.80, 7.08 p m. may recover. owe it to to From yourself transact East—12.26, 8.41. 6.48, 10.37 p m. (10.37 that has for its your There will be a before the cility object the and mail not distributed until hearing State prompt business with a following morn- Industrial banking bank, which ing.) accident commission at the -efficient dispatch of business.