Facts About Drugs Booklet
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A User's Guide to Methamphetamine
A USER’S GUIDE TO METHAMPHETAMINE A self-help guide to reduce harm for people who use methamphetamine 1st Edition, March 2017 Acknowledgements This booklet was adapted from an original publication created by The National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia. This information does not constitute medical advice. Please seek the immediate help of a qualified medical practitioner about any personal health concerns. This booklet is being distributed for information purposes only. In the current state of crisis related to crystal methamphetamine, this booklet is intended as a guide to reduce harm for people who use methamphetamine. It lists the most common features of methamphetamine use, ways to reduce harm associated with the use of meth, and strategies for cutting down and quitting. The best way to avoid problems with drugs is to not use them. We are grateful for the contributions of the Integrated Drug Strategies in Waterloo Region and Guelph Wellington, in particular the leadership of Adrienne Crowder and Lindsay Sprague. Don Roth, Kerry Manthenga, Shirley Hilton, and our community review team provided great support and helpful edits. Marcey Gray provided exemplary skill on the design, images and editing, with final expert assistance from Arkay Design and Print. We are thankful for the financial support to print copies from the Waterloo-Wellington Human Services and Justice Coordinating Committee. For more information please contact: Wellington Guelph Drug Strategy www.wgdrugstrategy.ca Waterloo Region Integrated Drugs Strategy www.waterlooregiondrugstrategy.ca Circulated with the support of: WaterlooRegion Integrated Drugs Strategy WaterlooRegion Integrated Drugs Strategy The best way to avoid problems with drugs is to not use them. -
Alcohol Mixed with Other Drugs
Alcohol Mixed with Other Drugs Stimulants Stimulants or “uppers”: Drugs that temporarily +increase alertness and energy Examples: Adderall, Ritalin, cocaine, methamphetamine FOCUS: Alcohol + Adderall Adderall: Used to treat ADHD and narcolepsy. Some students misuse Adderall in hopes it will help them study. “Misuse” is defined as taking a medication that was not prescribed to you, taking more Alcohol than what was prescribed to you or taking it for a dierent purpose than prescribed. Eects: Because alcohol is a depressant Use CUPS to remember the and Adderall is a stimulant, Adderall will symptoms of alcohol poisoning: mask alcohol’s eects. Mixing alcohol with • Cold, clammy, pale or bluish skin. a stimulant makes you less aware of alcohol's • Unconscious or unable to be roused. intoxicating eects, which can result in an • Puking repeatedly or uncontrollably. overdose or death. Additionally, mixing alcohol with Adderall (or any other stimulant) • Slow or irregular breathing. can cause an irregular heartbeat and cause cardiovascular complications. Stat: 4.3 percent of UC Davis undergraduates reported using a prescription stimulant in the last 12 months that was not prescribed to them. Sedative Depressants or “downers”: Sedating drugs +that reduce stimulation Examples: opiates, Xanax, Valium FOCUS: Alcohol + Opiates/Opioids Opiates: A group of drugs that are used for treating pain -examples: heroin, morphine, codeine, oxycontin, vicodin, fentanyl Alcohol Eects: When alcohol and opioids are Symptoms: taken at the same time, the sedative • Slow or irregular breathing eects of both drugs will magnify. This • Lowered pulse and can depress or even stop involuntary blood pressure functions, such as breathing, and will • Unconscious or unable increase the risk of overdose and death. -
Modafinil: a Review of Neurochemical Actions and Effects on Cognition
Neuropsychopharmacology (2008) 33, 1477–1502 & 2008 Nature Publishing Group All rights reserved 0893-133X/08 $30.00 www.neuropsychopharmacology.org Perspective Modafinil: A Review of Neurochemical Actions and Effects on Cognition ,1 1 Michael J Minzenberg* and Cameron S Carter 1Imaging Research Center, Davis School of Medicine, UC-Davis Health System, University of California, Sacramento, CA, USA Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved medication with wake-promoting properties. Pre-clinical studies of modafinil suggest a complex profile of neurochemical and behavioral effects, distinct from those of amphetamine. In addition, modafinil shows initial promise for a variety of off-label indications in psychiatry, including treatment-resistant depression, attention- deficit/hyperactivity disorder, and schizophrenia. Cognitive dysfunction may be a particularly important emerging treatment target for modafinil, across these and other neuropsychiatric disorders. We aimed to comprehensively review the empirical literature on neurochemical actions of modafinil, and effects on cognition in animal models, healthy adult humans, and clinical populations. We searched PubMed with the search term ‘modafinil’ and reviewed all English-language articles for neurochemical, neurophysiological, cognitive, or information-processing experimental measures. We additionally summarized the pharmacokinetic profile of modafinil and clinical efficacy in psychiatric patients. Modafinil exhibits robust effects on catecholamines, serotonin, glutamate, gamma amino-butyric acid, orexin, and histamine systems in the brain. Many of these effects may be secondary to catecholamine effects, with some selectivity for cortical over subcortical sites of action. In addition, modafinil (at well-tolerated doses) improves function in several cognitive domains, including working memory and episodic memory, and other processes dependent on prefrontal cortex and cognitive control. -
Prescription Stimulants
Prescription Stimulants What are prescription stimulants? Prescription stimulants are medicines generally used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy— uncontrollable episodes of deep sleep. They increase alertness, attention, and energy. What are common prescription stimulants? • dextroamphetamine (Dexedrine®) • dextroamphetamine/amphetamine combination product (Adderall®) • methylphenidate (Ritalin®, Concerta®). Photo by ©iStock.com/ognianm Popular slang terms for prescription stimulants include Speed, Uppers, and Vitamin R. How do people use and misuse prescription stimulants? Most prescription stimulants come in tablet, capsule, or liquid form, which a person takes by mouth. Misuse of a prescription stimulant means: Do Prescription Stimulants Make You • taking medicine in a way or dose Smarter? other than prescribed Some people take prescription stimulants to • taking someone else’s medicine try to improve mental performance. Teens • taking medicine only for the effect it and college students sometimes misuse causes—to get high them to try to get better grades, and older adults misuse them to try to improve their When misusing a prescription stimulant, memory. Taking prescription stimulants for people can swallow the medicine in its reasons other than treating ADHD or normal form. Alternatively, they can crush narcolepsy could lead to harmful health tablets or open the capsules, dissolve the powder in water, and inject the liquid into a effects, such as addiction, heart problems, vein. Some can also snort or smoke the or psychosis. powder. Prescription Stimulants • June 2018 • Page 1 How do prescription stimulants affect the brain and body? Prescription stimulants increase the activity of the brain chemicals dopamine and norepinephrine. Dopamine is involved in the reinforcement of rewarding behaviors. -
METHAMPHETAMINE (Trade Name: Desoxyn®; Street Names: Meth, Speed, Crystal, Glass, Ice, Crank, Yaba)
Drug Enforcement Administration Diversion Control Division Drug & Chemical Evaluation Section METHAMPHETAMINE (Trade Name: Desoxyn®; Street Names: Meth, Speed, Crystal, Glass, Ice, Crank, Yaba) March 2020 Introduction: of dependence and addiction. “Ice,” “Glass,” and “Crystal” are all Methamphetamine is a highly addictive drug with potent terms for concentrated d-methamphetamine HCl chunks that are central nervous system (CNS) stimulant properties. In the smoked. Yaba is a Thai name for a colored tablet containing 1960s, methamphetamine pharmaceutical products were methamphetamine combined with caffeine which is gaining widely available and extensively diverted and abused. The popularity among individuals who frequent “raves.” According to placement of methamphetamine into schedule II of the the National Survey on Drug Use and Health (NSDUH), 14.5 Controlled Substance Act (CSA) in 1971 and the removal of million individuals, aged 12 and older, reported nonmedical use of methamphetamine injectable formulations from the United methamphetamine at least once in their lifetime, and 1.4 million States market, combined with a better appreciation for its high within the past year. For 2017, lifetime use continued to increase abuse potential, led to a drastic reduction in the abuse of this with 14.7 million individuals, aged 12 and older, with 1.6 million in drug. However, a resurgence of methamphetamine abuse the past year. And, for the same age group in 2018, lifetime use occurred in the 1980s and it is currently considered a major was 14.9 million with 1.9 million in the past year. The 2017 drug of abuse. The widespread availability of Monitoring the Future (MTF) survey indicates a past year methamphetamine today is largely fueled by illicit production prevalence of 0.5% for 8th graders, 0.4% for 10th graders, and in large and small clandestine laboratories throughout the 0.6% for 12th graders. -
The Use and Impact of Cognitive Enhancers Among University Students: a Systematic Review
brain sciences Systematic Review The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review Safia Sharif 1 , Amira Guirguis 1,2,* , Suzanne Fergus 1,* and Fabrizio Schifano 1 1 Psychopharmacology, Substance Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK; [email protected] (S.S.); [email protected] (F.S.) 2 Institute of Life Sciences 2, Swansea University, Swansea SA2 8PP, Wales, UK * Correspondence: [email protected] (A.G.); [email protected] (S.F.) Abstract: Introduction: Cognitive enhancers (CEs), also known as “smart drugs”, “study aids” or “nootropics” are a cause of concern. Recent research studies investigated the use of CEs being taken as study aids by university students. This manuscript provides an overview of popular CEs, focusing on a range of drugs/substances (e.g., prescription CEs including amphetamine salt mixtures, methylphenidate, modafinil and piracetam; and non-prescription CEs including caffeine, cobalamin (vitamin B12), guarana, pyridoxine (vitamin B6) and vinpocetine) that have emerged as being misused. The diverted non-prescription use of these molecules and the related potential for dependence and/or addiction is being reported. It has been demonstrated that healthy students (i.e., those without any diagnosed mental disorders) are increasingly using drugs such as methylphenidate, a mixture of dextroamphetamine/amphetamine, and modafinil, for the purpose of increasing their alertness, concentration or memory. Aim: To investigate the level of knowledge, perception and impact of the use of a range of CEs within Higher Education Institutions. -
Methamphetamine Use: Lessons Learned
The author(s) shown below used Federal funds provided by the U.S. Department of Justice and prepared the following final report: Document Title: Methamphetamine Use: Lessons Learned Author(s): Dana Hunt, Ph.D.; Sarah Kuck; Linda Truitt, Ph.D. Document No.: 209730 Date Received: February 2006 Award Number: 99-C-008 This report has not been published by the U.S. Department of Justice. To provide better customer service, NCJRS has made this Federally- funded grant final report available electronically in addition to traditional paper copies. Opinions or points of view expressed are those of the author(s) and do not necessarily reflect the official position or policies of the U.S. Department of Justice. ANALYTIC SUPPORT PROGRAM CONTRACT TASK REQUIREMENT T-043: Methamphetamine Use: Lessons Learned Contract No. 99-C-008 Cambridge, MA Lexington, MA Hadley, MA Bethesda, MD Chicago, IL January 31, 2006 Prepared for Raymond C. German Contracting Officer Christine Crossland Senior Social Science Analyst National Institute of Justice Office of Justice Programs Acquisition Management Division 810 Seventh Street, SW Washington, D.C. 20001 Prepared by Dana Hunt, Ph.D. Sarah Kuck Abt Associates Inc. Linda Truitt, Ph.D. 55 Wheeler Street Cambridge, MA 02138 Contents Executive Summary...............................................................................................................iii History of Methamphetamine Use .................................................................................iii Trends.............................................................................................................................iii -
Keeping Youth Drug Free PDF 3.87 MB
Keeping Youth DRUG FREE Keeping Youth DRUG FREE U.S. Department of Health and Human Services Substance Abuse and Mental Health Services Administration Center for Substance Abuse Prevention Acknowledgments Electronic Access and Copies of Publication This publication was prepared for the Substance This publication may be downloaded or ordered at Abuse and Mental Health Services Administration http://store.samhsa.gov. Or call SAMHSA’s Store (SAMHSA) by the Center for Substance Abuse at 1-877-SAMHSA-7 (1-877-726-4727) Prevention (CSAP) under contract number (English and Español). HHSS277201600001C, with SAMHSA, U.S. Department of Health and Human Services (HHS). Recommended Citation David Lamont Wilson served as the Government Project Officer. Keeping Youth Drug Free. HHS Publication No. (SMA) 17-3772. Rockville, MD: Center for Substance Abuse Prevention, Substance Abuse and Mental Health Disclaimer Services Administration, 2017. The views, opinions, and content of this publication are those of the author and do not necessarily reflect Originating Office the views, opinions, or policies of SAMHSA or HHS. SAMHSA complies with applicable Federal civil rights Center for Substance Abuse Prevention, Substance laws and does not discriminate on the basis of race, Abuse and Mental Health Services Administration, color, national origin, age, disability, or sex. SAMHSA 5600 Fishers Lane, Rockville, MD 20857. cumple con las leyes federales de derechos civiles HHS Publication No. (SMA) 17-3772. aplicables y no discrimina por motivos de raza, color, First printed 2002. Revised 2017. nacionalidad, edad, discapacidad o sexo. Public Domain Notice All material appearing in this report is in the public domain and may be reproduced or copied without permission from SAMHSA. -
Recreational Drugs and Sleep an Overview
Recreational Drugs and Sleep An overview Dr Claire Durant Imperial College London, UK Recreational Drugs • Not all are illegal; (eg caffeine and alcohol legal) • Chemical substances taken to improve life in some way • Used commonly to reduce stress/ promote wake • Used parties/night clubs to improve sociability, • ……and to increase (perceived) dancing ability • Can also used to self medicate • All affect the neurotransmitters involved in sleep and wake • Sleep can be affected differently depending on: • Dose and timing of administration • Occasional vs chronic use (dependence)- withdrawal of almost all leads to sleep disturbance1 • 2Commonly used drugs in Europe: • Cannabis, Cocaine, Ecstasy (MDMA), Opioids (Heroin) 1Angarita et al. Addict Sci Clin Pract. 2016 Apr 26;11(1):9. 2European Drug Report 2015: Trends and Developments. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), (http://www.emcdda.europa.eu) Neurotransmitters in sleep & wake Sleep and waking influenced by a wide range of neurotransmitters - drugs that affect these will potentially alter sleep. Increasing Increasing Examples of Examples of Endogenous function function drugs promoting drugs promoting transmitter maintains promotes wakefulness sleep wakefulness sleep GABA Benzodiazepines Most recreational (Alcohol) Z drugs (Alcohol) drugs have actions at multiple receptors. Melatonin Melatonin Adenosine Antagonist: Caffeine Street preparations/ those purchased on the Noradrenaline Amphetamines (Cocaine/MDMA) internet …might not be what Serotonin SSRIs Mirtazapine, -
Methamphetamine Abuse BRADFORD T
Methamphetamine Abuse BRADFORD T. WINSLOW, MD, Swedish Medical Center Family Medicine Residency, Littleton, Colorado KENTON I. VOORHEES, MD, University of Colorado at Denver and Health Sciences Center, Denver, Colorado KATHERINE A. PEHL, MD, Denver Health Medical Center, Denver, Colorado Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produces a rapid, pleasur- able rush followed by euphoria, heightened attention, and increased energy. Possible adverse effects include myocardial infarction, stroke, seizures, rhabdomyolysis, cardiomyopathy, psychosis, and death. Chronic methamphetamine use is associated with neurologic and psychiatric symptoms and changes in physical appearance. High-risk sexual activity and transmission of human immunodeficiency virus are also associated with methamphetamine use. Use of methamphet- amine in women who are pregnant can cause placental abruption, intrauterine growth retardation, and preterm birth, and there can be adverse consequences in children exposed to the drug. Treatment of methamphetamine intoxication is primarily supportive. Treatment of methamphetamine abuse is behavioral; cognitive behavior therapy, contingency management, and the Matrix Model may be effective. Pharmacologic treatments are under investigation. (Am Fam Physician 2007;76:1169-74, 1175-6. Copyright © 2007 American Academy of Family Physicians.) ▲ Patient information: he synthetic stimulant metham- sex with men had used methamphetamine A handout on metham- phetamine (most commonly in the preceding six months.4 Methamphet- phetamine abuse, written by Sarah Jane Keiser, known as “meth” or “crystal meth”) amine use has also been associated with Georgetown University is a commonly abused drug in hepatitis C virus infection.6 School of Medicine, is T the United States. -
The Science of Addiction
Drugs, Brains, and Behavior The Science of Addiction Image: White Matter Fibers, Parietal Areas • www.humanconnectomeproject.org This publication is in the public domain and may be used or reproduced in its entirety without permission from NIDA. Citation of the source is appreciated. NIH Pub No. 14-5605 Printed April 2007 Revised February 2008, August 2010, July 2014 CONTENTS Preface ............................................................................................................................................................................ 1 Introduction .................................................................................................................................................................... 3 I. Drug Abuse and Addiction ........................................................................................................................................... 5 II. Preventing Drug Abuse: The Best Strategy ................................................................................................................. 11 III. Drugs and the Brain ................................................................................................................................................ 15 IV. Addiction and Health ................................................................................................................................................ 21 V. Treatment and Recovery ........................................................................................................................................... -
US-Crack Cocaine Booklet.Indd
THE TRUTH ABOUT CRACKCocaine Ball BaseJelly beans Nuggets Rock drugfreeworld.org US-Crack Cocaine Booklet.indd 1 4/14/15 7:16 PM WHY THIS BOOKLET WAS PRODUCED here is a lot of talk about drugs in the world—on the streets, at school, Ton the Internet and TV. Some of it is true, some not. Much of what you hear about drugs actually comes from those selling them. Reformed drug dealers have confessed they would have said anything to get others to buy drugs. Don’t be fooled. You need facts to avoid becoming hooked on drugs and to help your friends stay off them. That is why we have prepared this booklet—for you. Your feedback is important to us, so we look forward to hearing from you. You can visit us on the web at drugfreeworld.org and e-mail us at [email protected]. US-Crack Cocaine Booklet.indd 2 4/14/15 7:16 PM What is Crack Cocaine? rack cocaine is the crystal form of cocaine, is smoked Cwhich normally comes in a powder form.* rather than It comes in solid blocks or crystals varying in snorted color from yellow to pale rose or white. (taken in through Crack is heated and smoked. It is so named the nose), because it makes a cracking or popping sound an abuser when heated. can become addicted after his or her first time Crack, the most potent form in which cocaine trying crack. appears, is also the riskiest. It is between 75% Because of cocaine’s high cost, it has long been and 100% pure, far stronger and more potent considered a “rich man’s drug.” Crack, on the than regular cocaine.