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BLOOD RESEARCH September 2020 ARTICLE
VOLUME 55ㆍNUMBER 3 ORIGINAL BLOOD RESEARCH September 2020 ARTICLE Use of generic imatinib as first-line treatment in patients with chronic myeloid leukemia (CML): the GIMS (Glivec to Imatinib Switch) study Maria Gemelli1#, Elena Maria Elli2#, Chiara Elena3, Alessandra Iurlo4, Tamara Intermesoli5, Margherita Maffioli6, Ester Pungolino7, Maria Cristina Carraro8, Mariella D’Adda9, Francesca Lunghi10, Michela Anghileri11, Nicola Polverelli12, Marianna Rossi13, Mattia Bacciocchi14, Elisa Bono3, Cristina Bucelli4, Francesco Passamonti6, Laura Antolini15, Carlo Gambacorti-Passerini2,14 1Oncology Unit, San Gerardo Hospital, ASST-Monza, 2Hematology Division and Bone Marrow Unit, Ospedale San Gerardo, ASST- Monza, Monza, 3Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, 4Hematology Division, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, 5Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, 6Hematology Unit, Ospedale di Circolo, Varese, 7Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, 8Hematology and Transfusional Medicine Unit, ASST Fatebenefratelli Sacco, Milan, 9Department of Hematology, ASST Spedali Civili di Brescia, Brescia, 10Hematology and Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, IRCCS Milano, 11Oncology Department, ASST Lecco, Lecco, 12Chair of Hematology, Unit of Blood Diseases and Stem Cell Transplantation, University of Brescia, ASST Spedali Civili di Brescia, Brescia, 13Department of Hematology, Cancer Center, IRCCS Humanitas Research Hospital/Humanitas University, Rozzano, 14Department of Medicine and Surgery, University of Milano-Bicocca, 15Center of Biostatistics for Clinical Epidemiology, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy p-ISSN 2287-979X / e-ISSN 2288-0011 Background https://doi.org/10.5045/br.2020.2020130 Generic formulations of imatinib mesylate have been introduced in Western Europe since Blood Res 2020;55:139-145. -
Eurostat: Recognized Research Entity
http://ec.europa.eu/eurostat/web/microdata/overview This list enumerates entities that have been recognised as research entities by Eurostat. In order to apply for recognition please consult the document 'How to apply for microdata access?' http://ec.europa.eu/eurostat/web/microdata/overview The researchers of the entities listed below may submit research proposals. The research proposal will be assessed by Eurostat and the national statistical authorities which transmitted the confidential data concerned. Eurostat will regularly update this list and perform regular re-assessments of the research entities included in the list. Country City Research entity English name Research entity official name Member States BE Antwerpen University of Antwerp Universiteit Antwerpen Walloon Institute for Evaluation, Prospective Institut wallon pour l'Evaluation, la Prospective Belgrade and Statistics et la Statistique European Economic Studies Department, European Economic Studies Department, Bruges College of Europe College of Europe Brussels Applica sprl Applica sprl Brussels Bruegel Bruegel Center for Monitoring and Evaluation of Center for Monitoring and Evaluation of Brussels Research and Innovation, Belgian Science Research and Innovation, Service public Policy Office fédéral de Programmation Politique scientifique Centre for European Social and Economic Centre de politique sociale et économique Brussels Policy Asbl européenne Asbl Brussels Centre for European Policy Studies Centre for European Policy Studies Department for Applied Economics, -
Additional Rules Concerning Admission to the University of Udine for Prospective Students with Foreign Qualifications
ADDITIONAL RULES CONCERNING ADMISSION TO THE UNIVERSITY OF UDINE FOR PROSPECTIVE STUDENTS WITH FOREIGN QUALIFICATIONS. ACADEMIC YEAR 2019/2020. General Information Each study programme has a number of vacant places reserved for foreign non-EU students. This information may be consulted on the online data bank of the Italian Ministry of Education, Universities and Research page - Vacant places reserved for foreign non-EU students (http://www.studiare-in-italia.it/studentistranieri/). Foreign non-EU students must submit their application for pre-enrolment to the Italian Embassy or Consulate in their Country of residence. On completion of the pre-enrolment procedure, a visa for study purposes will be issued in order to enter Italy. In addition, foreign non-EU students must submit the application for a residence permit for study to the competent police headquarters of the city in which they intend to establish their abode within 8 days after their arrival in Italy with a national D type visa for studies (university enrollment). Access requirements to Bachelor’s and Master’s Degree Courses are compulsory for all students with a foreign qualification, regardless of their nationality, whether an EU Country or non-EU Country releases it. Candidates are reminded that the “Declaration of value” or “Statement of comparability for foreign qualification – Cimea” will not affect the Teaching Committee’s academic evaluation. ADMISSION REQUIREMENTS FOR FIRST (BACHELOR DEGREES) AND SINGLE CYCLE DEGREES (5-YEAR OR 6-YEAR MASTER DEGREES) Prospective students who hold a foreign qualification and want to apply for a First Cycle Degree or a Single Cycle Degree Course must follow the recognition procedure for foreign qualifications. -
About the Authors
About the Authors Nicola Bellantuono is a Research Fellow in Operations Management at Politecnico di Bari (Italy). He holds a Laurea Degree in Management Engineering (2004) and a PhD in Environmental Engineering (2008). His main research interests deal with exchange mechanisms and coordination schemes for supply chain management, procurement of logistics services, open innovation processes, and corporate social responsibility. Valeria Belvedere is an Assistant Professor in Production and Operations Management at the Department of Management and Technology, Bocconi University, and Professor at the Operations and Technology Management Unit of the SDA Bocconi School of Management. Her main fields of research and publication concern: manufacturing and logistics performance measurement and management; manufacturing strategy; service operations management; and behavioral operations. Elliot Bendoly is an Associate Professor and Caldwell Research Fellow in Information Systems and Operations Management at Emory University’s Goizueta Business School. He currently serves as a senior editor at the Production and Operations Management journal, associate editor for the Journal of Operations Management (Business Week and Financial Times listed journals). Aside from these outlets, he has also published in such widely respected outlets at Information Systems Research, MIS Quarterly, Journal of Applied Psychology, Journal of Supply Chain Management, and Decision Sciences and Decision Support Systems. His research focuses on operational issues in IT utilization and behavioral dynamics in operations management. Stephanie Eckerd is an Assistant Professor at the University of Maryland’s Robert H. Smith School of Business where she teaches courses in supply chain management. Her research uses survey and experiment methodologies to investigate how social and psychological variables affect buyer–supplier relationships. -
Demos / Posters
Demos / Posters The map of the rooms is available here DEMO SESSION 1 Tuesday, April 16 (10:30 - 16:00) Room: Corridoio Nizza Move-with-the-Sun or Move-with-the-Moon? Wide-area CloudNet Migrations Under Latency and Resource Constraints 1 / 14 Demos / Posters Johannes Grassler (TU Berlin & T-Labs, Germany); Stefan Schmid (T-Labs & TU Berlin, Germany); Anja Feldmann (TU-Berlin & Deutsche Telekom Laboratories, Germany) OPRSFEC: A Middleware of Packet Loss Recovery in Live Multicast Smart TV System Xiuyan Jiang (Fudan University, P.R. China); De jian Ye (Fudan University, P.R. China); Yiming Chen (Fudan University, P.R. China) Lossless Virtual Networks Daniel Crisan (ETHZ & IBM Research, Switzerland); Robert Birke (IBM Zurich Research Laboratory, Switzerland); Cyriel Minkenberg (IBM Research - Zurich, Switzerland); Mitchell Gusat (IBM Zurich research laboratory, Switzerland) Live Evaluation of Quality of Experience for Video Streaming and Web Browsing Louis Plissonneau (Orange Labs, France); Heng Cui (EURECOM, France); Ernst W Biersack (EURECOM, France) A User-centric Approach to Trust Management in Wi-Fi Networks Carlos Ballester (University of Geneva, Switzerland); Jean-Marc Seigneur (University of Geneva, Switzerland); Paolo Di Francesco (Level7, Italy); Valentin Moreno (FON, Spain); Rute C. Sofia (SITI, Universidade Lusófona, Portugal); Waldir Moreira (SITILabs, University Lusofona, Portugal); Alessandro Bogliolo (University of Urbino, Italy); Nuno Martins (Caixa Mágica Software, Portugal) User-centric Mobile Multimedia Service Delivery: -
Masters Erasmus Mundus Coordonnés Par Ou Associant Un EESR Français
Les Masters conjoints « Erasmus Mundus » Masters conjoints « Erasmus Mundus » coordonnés par un établissement français ou associant au moins un établissement français Liste complète des Masters conjoints Erasmus Mundus : http://eacea.ec.europa.eu/erasmus_mundus/results_compendia/selected_projects_action_1_master_courses_en.php *Master n’offrant pas de bourses Erasmus Mundus *ACES - Joint Masters Degree in Aquaculture, Environment and Society (cursus en 2 ans) UK-University of the Highlands and Islands LBG FR- Université de Nantes GR- University of Crete http://www.sams.ac.uk/erasmus-master-aquaculture ADVANCES - MA Advanced Development in Social Work (cursus en 2 ans) UK-UNIVERSITY OF LINCOLN, United Kingdom DE-AALBORG UNIVERSITET - AALBORG UNIVERSITY FR-UNIVERSITÉ PARIS OUEST NANTERRE LA DÉFENSE PO-UNIWERSYTET WARSZAWSKI PT-UNIVERSIDADE TECNICA DE LISBOA www.socialworkadvances.org AMASE - Joint European Master Programme in Advanced Materials Science and Engineering (cursus en 2 ans) DE – Saarland University ES – Polytechnic University of Catalonia FR – Institut National Polytechnique de Lorraine SE – Lulea University of Technology http://www.amase-master.net ASC - Advanced Spectroscopy in Chemistry Master's Course FR – Université des Sciences et Technologies de Lille – Lille 1 DE - University Leipzig IT - Alma Mater Studiorum - University of Bologna PL - Jagiellonian University FI - University of Helsinki http://www.master-asc.org Août 2016 Page 1 ATOSIM - Atomic Scale Modelling of Physical, Chemical and Bio-molecular Systems (cursus -
Emidio Capriotti Phd CURRICULUM VITÆ
Emidio Capriotti PhD CURRICULUM VITÆ Name: Emidio Capriotti Nationality: Italian Date of birth: February, 1973 Place of birth: Roma, Italy Languages: Italian, English, Spanish Positions Oct 2019 Associate Professor: Department of Pharmacy and Biotechnology (FaBiT). University of Bologna, Bologna, Italy 2016-2019 Senior Assistant Professor (RTD type B): Department of Pharmacy and Biotechnology (FaBiT) and Department of Biological, Geological, and Environmental Sciences (BiGeA). University of Bologna, Bologna, Italy. 2015-2016 Junior Group Leader: Institute of Mathematical Modeling of Biological Systems, University of Düsseldorf, Düsseldorf, Germany 2012-2015 Assistant Professor: Division of Informatics, Department of Pathology, University of Alabama at Birmingham (UAB), Birmingham (AL), USA. 2011-2012 Marie-Curie IOF: Contracted Researcher at the Department of Mathematics and Computer Science, University of Balearic Islands (UIB), Palma de Mallorca, Spain. 2009-2011 Marie-Curie IOF: Postdoctoral Researcher at the Helix Group, Department of Bioengineering, Stanford University, Stanford (CA), USA. 2006-2009 Postdoctoral Researcher in the Structural Genomics Group at Department of Bioinformatics and Genetics, Prince Felipe Research Center (CIPF) Valencia, Spain. 2004-2006 Contract researcher at Department of Biology, University of Bologna, Bologna, Italy. 2001-2003 Ph.D student in Physical Sciences at University of Bologna, Bologna, Italy. Education Sep 2004 Master in Bioinformatics (first level) University of Bologna, Bologna (Italy). Jun 2004 Ph.D. in Physical Sciences University of Bologna, Bologna (Italy). Jul 1999 Laurea (B.S.) Degree in Physical Sciences, score 106/110 University of Bologna, Bologna (Italy). Visiting Jun 2012 – Jul 2012 Prof. Frederic Rousseau and Prof. Joost Schymkowitz, VIB Switch Laboratory, KU Leuven, Leuven (Belgium) May 2009 Prof. -
Curriculum Vitae Carlo Filippi
Curriculum Vitae Carlo Filippi Office address and URLs Department of Economics and Management - University of Brescia Contrada S. Chiara 50 - 25122 BRESCIA. Tel: +39 - 030 298 8576 E-mail: [email protected] OR group: http://or-brescia.unibs.it/ Scopus: https://www.scopus.com/authid/detail.uri?authorId=7006884051 Publons: https://publons.com/researcher/532100/carlo-filippi Google Scholar: http://scholar.google.it/citations?user=Wrwp_L0AAAAJ&hl=it CURRENT POSITION Associate Professor of Operations Research (MAT / 09) National Scientific Qualification, Full Professor, Operations Research. PROFESSIONAL EXPERIENCE 01/09/2006 – to the current date: Associate Professor of Operations Research (MAT / 09) University of Brescia - Department of Economics and Management, Brescia (Italy) Teaching: Currently Professor of Introduction to Logistics (6CFU, Laurea Master's Degree in Management), Supply Chain Management (6 CFU, Master's Degree in Management), Business Decision Analysis - AG (6 CFU, Bachelor's Degrees in Economics). Previously, professor and substitute teacher of various courses on logistics topics and decision support methods for master's degrees and on basic computer science topics and optimization for three-year degrees. Supervisor over 50 final reports for three-year and master's degrees in Economics, on topics related to logistics, optimization, information systems, electronic marketing. Research: Production of articles in international scientific journals and presentations at national and international sector conferences on topics -
(Brachytherapy) Education in Italy: Results of the INTERACTS Survey
Review Papers Review paper Current state of interventional radiotherapy (brachytherapy) education in Italy: results of the INTERACTS survey Luca Tagliaferri, MD, PhD1, György Kovács, MD, PhD2, Cynthia Aristei, MD3, Vitaliana De Sanctis, MD4, Fernando Barbera, MD5, Alessio Giuseppe Morganti, MD6, Calogero Casà, MD7, Bradley Rumwell Pieters, MD, PhD8, Elvio Russi, MD9, Lorenzo Livi, MD10, Renzo Corvò, MD11, Andrea Giovagnoni, MD12, Umberto Ricardi, MD13, Vincenzo Valentini, MD14,15, Stefano Maria Magrini, MD16 and the Directors of the Italian Radiation Oncology Schools** 1Chair of the Brachytherapy, Interventional Radiotherapy and IORT Study Group of the Italian Radiotherapy and Clinical Oncology Society (AIRO); Gemelli ART (Advanced Radiation Therapy), UOC Radioterapia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 2INTERACTS (Interventional Radiotherapy Active Teaching School) Educational Program Director; Head, Interdisciplinary Brachytherapy Unit, University of Lübeck/UKSH CL, Lübeck, Germany, 3Past Chair of AIRO Brachytherapy study group; Head, Radiation Oncology Section, Department of Surgery and Biomedical Sciences, University of Perugia and Perugia General Hospital, Perugia, Italy, 4Deputy Chair of the Brachytherapy, Interventional Radiotherapy and IORT AIRO Study Group; Department of Radiation Oncology, Faculty of Medicina e Psicologia, Sant’Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy, 5Board Member of the Brachytherapy, Interventional Radiotherapy and IORT AIRO Study Group; Head, Brachytherapy -
International Incoming Student's Guide
INTERNATIONAL INCOMING STUDENT’S GUIDE What you need to get the most out of Pavia and its university, and survive! UNIVERSITÀ DEGLI STUDI DI PAVIA Corso Strada Nuova 65, 27100 Pavia, Italy e-mail: [email protected] Tel. +39 0382 984021 Fax +39 0382 984695 Index 1. INTRODUCTION 9 1.1 THE INTERNATIONAL RELATIONS OFFICE AND WELCOME POINT 9 1.2 THE ITALIAN ACADEMIC SYSTEM 9 1.3 FACULTIES 10 1.4 PLACES YOU NEED FOR YOUR STUDIES 11 2. MEANS OF TRANSPORT 12 2.1 AIRPLANES AND AIRPORTS GETTING TO PAVIA 12 2.2 TRAINS AND STATIONS 12 2.2.1 TICKET BIGLIETTO 12 2.3 BUSES AND COACHES AUTOBUS E CORRIERE 13 3. BUREAUCRACY 15 3.1 LOST PASSPORT 15 4. UNIVERSITY OF PAVIA 16 4.1 SERVICES 16 4.1.1 CANTEENS MENSA 16 4.1.2 COMPUTER FACILITIES AND WI-FI CONNECTION 17 4.1.3 BOOKS LIBRI 17 4.1.4 LIBRARIES AND OPAC BIBLIOTECHE 17 4.1.5 BOOKSTORES LIBRERIE 18 4.2 UNIVERSITY LIFE VITA UNIVERSITARIA 19 4.2.1 C.U.S. UNIVERSITY SPORTS CENTRE 19 4.2.2 S.A.I.S.D. FACILITIES FOR DISABLED STUDENTS 19 4.2.3 STUDENT ASSOCIATIONS 19 4.2.4 MERCHANDISING 20 4.2.5 UCAMPUS 20 5. HEALTH 21 5.1 HEALTH INSURANCE ASSICURAZIONE SANITARIA 21 5.2 FIRST AID PRONTO SOCCORSO 21 5.3 PHARMACIES FARMACIA 22 5.4 MEDICINES MEDICINALI 23 6. FOOD AND FUN 25 6.1 SUPERMARKETS AND MARKET PLACES 25 6.2 BARS, PIZZERIAS AND RESTAURANTS 26 6.3 NIGHTLIFE - WHAT DOES PAVIA OFFER AT NIGHT? 27 7. -
HLA Matching Affects Clinical Outcome of Adult Patients
Bone Marrow Transplantation (2009) 44, 571–577 & 2009 Macmillan Publishers Limited All rights reserved 0268-3369/09 $32.00 www.nature.com/bmt ORIGINAL ARTICLE HLA matching affects clinical outcome of adult patients undergoing haematopoietic SCT from unrelated donors: a study from the Gruppo Italiano Trapianto di Midollo Osseo and Italian Bone Marrow Donor Registry R Crocchiolo1,5, F Ciceri1, K Fleischhauer2, R Oneto3, B Bruno3, S Pollichieni4, N Sacchi4, MP Sormani5, R Fanin6, G Bandini7, F Bonifazi7, A Bosi8, A Rambaldi9, PE Alessandrino10, M Falda11 and A Bacigalupo3 1Department of Oncology, Hematology and Bone Marrow Transplantation Unit, S Raffaele Scientific Institute, Milano, Italy; 2Immunogenetics Laboratory, S Raffaele Scientific Institute, Milano, Italy; 3Department of Hemato-Oncology, Division of Hematology, Ospedale San Martino, Genova, Italy; 4Italian Bone Marrow Donor Registry, Ospedale Galliera, Genova, Italy; 5Biostatistics Unit, Department of Health Sciences (DISSAL), University of Genova, Genova, Italy; 6Division of Hematology and Bone Marrow Transplantation, University of Udine, Udine, Italy; 7Institute of Hematology and Clinical Oncology ‘LA Seragnoli’, Bologna, Italy; 8Department of Hematology, University of Florence, Florence, Italy; 9Department of Oncology and Hematology, Division of Hematology, Ospedali Riuniti, Bergamo, Italy; 10Division of Hematology, University of Pavia, Pavia, Italy and 11Division of Hematology, Ospedale San Giovanni Battista, Torino, Italy The importance of HLA donor–recipient matching in Keywords: haematopoietic SCT; haematological malig- unrelated haematopoietic SCT (HSCT) is the subject of nancy; unrelated donor; HLA matching. debate. In this retrospective study, we analyzed 805 adult patients from the Italian Registry receiving HSCT for a haematological malignancy from January 1999 to June 2006 and correlated the degree of HLA matching with Introduction transplant outcome. -
Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma In
www.nature.com/scientificreports OPEN Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Received: 5 September 2018 Accepted: 23 January 2019 Liver Disease Published: xx xx xxxx Serena Pelusi1,2,16, Guido Baselli 1, Alessandro Pietrelli2, Paola Dongiovanni2, Benedetta Donati1, Misti Vanette McCain3, Marica Meroni1, Anna Ludovica Fracanzani1,2, Renato Romagnoli 4, Salvatore Petta5, Antonio Grieco6, Luca Miele 6, Giorgio Soardo7, Elisabetta Bugianesi8, Silvia Fargion1,2, Alessio Aghemo9, Roberta D’Ambrosio10, Chao Xing 11, Stefano Romeo12,13, Rafaele De Francesco14, Helen Louise Reeves3,15 & Luca Vittorio Carlo Valenti1,2,16 Nonalcoholic fatty liver disease (NAFLD) is a rising cause of hepatocellular carcinoma (HCC). We examined whether inherited pathogenic variants in candidate genes (n = 181) were enriched in patients with NAFLD-HCC. To this end, we resequenced peripheral blood DNA of 142 NAFLD-HCC, 59 NAFLD with advanced fbrosis, and 50 controls, and considered 404 healthy individuals from 1000 G. Pathogenic variants were defned according to ClinVar, likely pathogenic as rare variants predicted to alter protein activity. In NAFLD-HCC patients, we detected an enrichment in pathogenic (p = 0.024), and likely pathogenic variants (p = 1.9*10−6), particularly in APOB (p = 0.047). APOB variants were associated with lower circulating triglycerides and higher HDL cholesterol (p < 0.01). A genetic risk score predicted NAFLD-HCC (OR 4.96, 3.29–7.55; p = 5.1*10−16), outperforming the diagnostic accuracy of common genetic risk variants, and of clinical risk factors (p < 0.05). In conclusion, rare pathogenic variants in genes involved in liver disease and cancer predisposition are associated with NAFLD-HCC development.