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JMIR Research Protocols Ongoing Trials, Grant Proposals, Formative Research, Methods, Early Results Volume 9 (2020), Issue 1 ISSN: 1929-0748 Contents Protocols Factors Associated With Trial Completion and Adherence in App-Based N-of-1 Trials: Protocol for a Randomized Trial Evaluating Study Duration, Notification Level, and Meaningful Engagement in the Brain Boost Study (e16362) Jason Bobe, Jacqueline Buros, Eddye Golden, Matthew Johnson, Michael Jones, Bethany Percha, Ryan Viglizzo, Noah Zimmerman. 5 Caring Near and Far by Connecting Community-Based Clients and Family Member/Friend Caregivers Using Passive Remote Monitoring: Protocol for a Pragmatic Randomized Controlled Trial (e15027) Lorie Donelle, Sandra Regan, Michael Kerr, Merrick Zwarenstein, Michael Bauer, Grace Warner, Wanrudee Isaranuwatchai, Aleksandra Zecevic, Elizabeth Borycki, Dorothy Forbes, Lori Weeks, Bev Leipert, Emily Read. 14 Using Augmented Reality to Motivate Oral Hygiene Practice in Children: Protocol for the Development of a Serious Game (e10987) Susy Amantini, Alexandre Montilha, Bianca Antonelli, Kim Leite, Daniela Rios, Thiago Cruvinel, Natalino Lourenço Neto, Thais Oliveira, Maria Machado. 23 Relationship Education and HIV Prevention for Young Male Couples Administered Online via Videoconference: Protocol for a National Randomized Controlled Trial of 2GETHER (e15883) Michael Newcomb, Elissa Sarno, Emily Bettin, James Carey, Jody Ciolino, Ricky Hill, Christopher Garcia, Kathryn Macapagal, Brian Mustanski, Gregory Swann, Sarah Whitton. 33 Behavioral, Nutritional, and Genetic Risk Factors of Colorectal Cancers in Morocco: Protocol for a Multicenter Case-Control Study (e13998) Meimouna Mint Sidi Ould Deoula, Inge Huybrechts, Khaoula El Kinany, Hanae Boudouaya, Zineb Hatime, Achraf El Asri, Abdelilah Benslimane, Chakib Nejjari, Ibrahimi Sidi Adil, Karima El Rhazi. 48 Assessing Whether Meditation Improves Quality of Life for Adolescent Girls With Polycystic Ovary Syndrome: Protocol for a Randomized Controlled Trial (e14542) Erandi Hewawasam, Leah Brennan, Lynne Giles, Mary Hull, Asha Short, Robert Norman, Alexia Peña. 58 Design and Development of a Viral Hepatitis and HIV Infection Screening Program (Hprolipsis) for the General, Greek Roma, and Migrant Populations of Greece: Protocol for Three Cross-Sectional Health Examination Surveys (e13578) Giota Touloumi, Argiro Karakosta, Vana Sypsa, Ioanna Petraki, Olga Anagnostou, Agis Terzidis, Niki Voudouri, Doctors Of The World Greek Delegation, Magda Gavana, Apostolos Vantarakis, George Rachiotis, Maria Kantzanou, Theofilos Rosenberg, George Papatheodoridis, Angelos Hatzakis, Hprolipsis Study Group. 68 JMIR Research Protocols 2020 | vol. 9 | iss. 1 | p.1 XSL·FO RenderX Early Signs Monitoring to Prevent Relapse in Psychosis and Promote Well-Being, Engagement, and Recovery: Protocol for a Feasibility Cluster Randomized Controlled Trial Harnessing Mobile Phone Technology Blended With Peer Support (e15058) Andrew Gumley, Simon Bradstreet, John Ainsworth, Stephanie Allan, Mario Alvarez-Jimenez, Louise Beattie, Imogen Bell, Max Birchwood, Andrew Briggs, Sandra Bucci, Emily Castagnini, Andrea Clark, Sue Cotton, Lidia Engel, Paul French, Reeva Lederman, Shon Lewis, Matthew Machin, Graeme MacLennan, Claire Matrunola, Hamish McLeod, Nicola McMeekin, Cathrine Mihalopoulos, Emma Morton, John Norrie, Frank Reilly, Matthias Schwannauer, Swaran Singh, Lesley Smith, Suresh Sundram, David Thomson, Andrew Thompson, Helen Whitehill, Alison Wilson-Kay, Christopher Williams, Alison Yung, John Farhall, John Gleeson. 85 Effects of Bluetooth-Enabled Desk Ellipticals on Office Work Performance: Rationale, Design, and Protocol for a Randomized Trial With Overweight and Obese Adults (e16275) Liza Rovniak, Marc Adams, Christopher Sciamanna, Lan Kong, Nicole Sullivan, Sara Costalas, Melissa Bopp, Ashley Kuzmik. 104 The Use of Web-Based Support Groups Versus Usual Quit-Smoking Care for Men and Women Aged 21-59 Years: Protocol for a Randomized Controlled Trial (e16417) Cornelia Pechmann, Douglas Calder, Connor Phillips, Kevin Delucchi, Judith Prochaska. 118 A Mobile Phone±Based Telemonitoring Program for Heart Failure Patients After an Incidence of Acute Decompensation (Medly-AID): Protocol for a Randomized Controlled Trial (e15753) Emily Seto, Heather Ross, Alana Tibbles, Steven Wong, Patrick Ware, Edward Etchells, Jeremy Kobulnik, Tamanna Chibber, Stephanie Poon. 128 Self-Management Characterization for Families of Children With Medical Complexity and Their Social Networks: Protocol for a Qualitative Assessment (e14810) Rupa Valdez, Christopher Lunsford, Jiwoon Bae, Lisa Letzkus, Jessica Keim-Malpass. 137 Smartphone Cardiac Rehabilitation, Assisted Self-Management Versus Usual Care: Protocol for a Multicenter Randomized Controlled Trial to Compare Effects and Costs Among People With Coronary Heart Disease (e15022) Jonathan Rawstorn, Kylie Ball, Brian Oldenburg, Clara Chow, Sarah McNaughton, Karen Lamb, Lan Gao, Marj Moodie, John Amerena, Voltaire Nadurata, Christopher Neil, Stuart Cameron, Ralph Maddison. 146 Movement-Evoked Pain Versus Pain at Rest in Postsurgical Clinical Trials and Meta-Analyses: Protocol for a Follow-Up Systematic Review (e15309) Daenis Camiré, Jason Erb, Henrik Kehlet, Timothy Brennan, Ian Gilron. 164 Mobile Apps for Health Behavior Change: Protocol for a Systematic Review (e16931) Madison Milne-Ives, Ching Lam, Michelle Van Velthoven, Edward Meinert. 168 Teaching Real-World Evidence: Protocol for a Systematic Review (e16941) Ching Lam, Michelle van Velthoven, Hassan Chaudhury, Edward Meinert. 174 The Association Between Selected Molecular Biomarkers and Ambulatory Blood Pressure Patterns in African Chronic Kidney Disease and Hypertensive Patients Compared With Normotensive Controls: Protocol for a Longitudinal Study (e14820) Abiodun Adeoye, Oladimeji Adebayo, Busayo Abiola, Bamidele Iwalokun, Bamidele Tayo, Fadi Charchar, Akinlolu Ojo, Richard Cooper. 179 A Smartphone App Combining Global Positioning System Data and Ecological Momentary Assessment to Track Individual Food Environment Exposure, Food Purchases, and Food Consumption: Protocol for the Observational FoodTrack Study (e15283) Maartje Poelman, Frank van Lenthe, Simon Scheider, Carlijn Kamphuis. 187 JMIR Research Protocols 2020 | vol. 9 | iss. 1 | p.2 XSL·FO RenderX An Electronic Health Platform for Monitoring Health Conditions of Patients With Hypertension in the Brazilian Public Health System: Protocol for a Nonrandomized Controlled Trial (e15299) Ana De Marchi, Ana Alves, Carla Gonçalves, Cristiano Cervi, Daiana Biduski, Ericles Bellei, Guilherme Madalozzo, Ivana Da Cruz, Jeangrei Veiga, João Rodriguez, Luciano Ferretto, Luiz Bin, Marcelo Rebonatto, Marilene Portella, Mateus Roman, Nathália Cechetti, Rafael Rieder, Raquel Debon, Simiane Volpi. 202 A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study (e14525) Amber Brooks, David Miller Jr, Jason Fanning, Erin Suftin, M Reid, Brian Wells, Xiaoyan Leng, Robert Hurley. 212 Using Mobile Devices to Deliver Lifestyle Interventions Targeting At-Risk High School Students: Protocol for a Participatory Design Study (e14588) Ulrika Müssener, Marie Löf, Preben Bendtsen, Marcus Bendtsen. 221 Development of Serious Games (Equit'Game) to Address Health and Environmental Inequalities: Protocol for an App-Delivered Program to Perform a Territorial Diagnosis (e11786) Wahida Kihal Talantikite, Damien Renou, Arnold Magdelaine, William Harang, Denis Zmirou-Navier, Severine Deguen. 230 Evaluation of a Health Information Technology±Enabled Panel Management Platform to Improve Anticoagulation Control in a Low-Income Patient Population: Protocol for a Quasi-Experimental Design (e13835) Valy Fontil, Dhruv Kazi, Roy Cherian, Shin-Yu Lee, Urmimala Sarkar. 241 Screening University Students for Health Checks With an Electronic Health Questionnaire in Finland: Protocol for a Retrospective, Register-Based Cohort Study (e14535) Susanna Paldanius, Noora Seilo, Kristina Kunttu, Reija Autio, Minna Kaila. 251 The Canadian Partnership Against Cancer Rectal Cancer Project: Protocol for a Pan-Canadian, Multidisciplinary Quality Improvement Initiative to Optimize the Quality of Rectal Cancer Care (e15535) Amandeep Pooni, Selina Schmocker, Carl Brown, Anthony MacLean, Lara Williams, Nancy Baxter, Marko Simunovic, Alexander Liberman, Sebastien Drolet, Katerina Neumann, Kartik Jhaveri, Richard Kirsch, Erin Kennedy. 260 Quality of Inpatient Tuberculosis Health Care in High-Burden Resource-Limited Settings: Protocol for a Comprehensive Mixed Methods Assessment Study (e13903) Nune Truzyan, Zaruhi Grigoryan, Lusine Musheghyan, Byron Crape, Varduhi Petrosyan. 282 Developing an Evidence-Based Nursing Handover Standard for a Multi-Site Public Hospital in Switzerland: Protocol for a Web-Based, Modified Delphi Study (e15910) Nadine Tacchini-Jacquier, Els de Waele, Peter Urben, Pierre Turini, Henk Verloo. 289 Testing the Effectiveness of Enhanced Alcohol Warning Labels and Modifications Resulting From Alcohol Industry Interference in Yukon, Canada: Protocol for a Quasi-Experimental Study (e16320) Kate Vallance, Timothy Stockwell, David Hammond, Simran Shokar, Nour Schoueri-Mychasiw, Thomas Greenfield, Jonathan McGavock, Jinhui Zhao, Ashini Weerasinghe, Erin Hobin. 300 The Impact of Hearing Impairment on the Life Trajectories of Aboriginal Children in Remote Australia: Protocol for the Hearing Loss in Kids Project (e15464) Jiunn-Yih Su, Vincent