FACULTY PROFILE BRAIN 2020

Sandra is currently based at the Chinese University of as an Associate Professor in the Department of Psychiatry and Assistant Dean for Student Support in the Faculty of Medicine.

Sandra received her MBChB from the Chinese University of Hong Kong and is a Fellow of the Royal College of Psychiatrists (UK), the Hong Kong College of Psychiatrists, and the Hong Kong Academy of Medicine (Psychiatry). Her current clinical expertise encompasses mood disorders, neuroimaging-guided neuromodulation for treatment-refractory depression, and psychodynamic psychotherapy; while her research interests lie in functional brain mapping for mood disorders, and network- informed transcranial magnetic stimulation for treatment-refractory major depressive disorder. Sandra CHAN Her research has been widely published in leading international peer- review journals. She has received multiple competitive grants and funding for both population-based and clinic-based studies from organisations such as the US National Institute of Health, the Hong Kong Research Grant Council and the Hospital Authority Health Care & Promotion Fund, where she regularly collaborates with local and international institutions in the

capacity of principle or co-investigator. Aside from her everyday duties, Sandra is actively involved with professional societies, and holds many positions including, among many others, the incumbent Chair of the Research Committee and Council Member of the Hong Kong College of Psychiatrists; Chair and Convenor of the DEC Subcommittee for MMR, the Mental Health Association of Hong Kong; and a Member of the World Psychiatric Association Psychotherapy Section.

Carol is an Assistant Professor at Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong. Carol’s main research interest is “imaging of the eye”, based on the concept that the eyes are the “window” to the human circulation and nervous systems. She has been working in the field of ocular imaging for more than 13 years in Hong Kong and in , focus on development and application of image analysis techniques and artificial intelligence for studying eye diseases, and also relationship between retinal imaging markers and Alzheimer’s diseases. Carol is a principal investigator of multiple research grants on the Carol CHEUNG development and application of novel imaging techniques, and how these techniques can be used to improve clinical practice and public health outcomes.

Carol has authored more than 190 original research articles and 21 review articles in SCI international indexed peer reviewed journals, and 10 book chapters. In addition to Carol’s research and teaching, she serves as a regular reviewer for international scientific journals and for international grant funding agencies. She is a secretary-general of Asia Pacific Ocular Imaging Society. She is a council board member and treasurer of Asia Pacific Tele-Ophthalmology Society.

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Xiujuan has over 10 years of research experience in neuroimaging and neuroscience. Her research ranges from advanced methodology development in neuroimaging to the investigation of neural basis of cognitive/emotional processing under developing brain and mentally diseased populations. Before moving to the Chinese University of Hong Kong, she worked as a research faculty member at the University of North Carolina (UNC), USA and the University of Hong Kong (HKU). She serves as regular reviewers and board members for world-leading journals and conferences in neuroimaging and medical imaging fields.

Xiujuan GENG Xiujuan research has been published in high-impact international journals, such as Brain, Cerebral Cortex, Neuroimage, IEEE Transactions on Medical Imaging, etc. Her current research focuses on building multi- modal imaging and machine learning algorithms to study the early brain developmental trajectory in infants and children, and the neuroimaging markers predictive to later behavioural outcomes.

Ying-Yi is Choh-Ming Li Professor of Marketing at The Chinese University of Hong Kong (CUHK). Ying-Yi obtained her Ph.D. from Columbia University. Before returning to teach at CUHK, Ying-Yi has taught at Hong Kong University of Science and Technology, University of Illinois at Urbana-Champaign (USA), and Nanyang Technological University (Singapore). Her research focuses on culture and cognition, multicultural identity and intergroup relations, and uses multidisciplinary methods, including social psychological (e.g., priming), economic (behavioral games), and bio-physiological methods (e.g., fMRI, genetic analysis). Ying-Yi HONG Ying-Yi has published over 120 journal articles and book chapters and her

work has been extensively cited (H=58). She has received several awards for her pioneering work, including the Otto Klineberg Intercultural and International Relations Award in 2001, the International Society for Self and Identity Outstanding Early Career Award in 2004 and the Nanyang Award for Research Excellence in 2013. Her book The Oxford Handbook of Multicultural Identity has won the 2015 Ursula Gielen Global Psychology Book Award. She just completed a fellowship (2018-2019) at Center for Advanced Study in the Behavioral Sciences at Stanford University. FACULTY PROFILE

Yaou, as a neuroradiologist, has been dedicating to basic and clinical neuroimaging research and focusing on elucidating the MRI features of neuroimmune disease especially neuromyelitis optica spectrum disorder (NMOSD) and its clinical relevance. He has symmetrically demonstrated the specific patterns of brain damage in NMOSD including alterations of visual, motor and cognition related brain areas and subtle widespread white matter demyelination. Furthermore, the neural mechanism of cognitive impairment in NMOSD was revealed mainly in deep gray matter specifically hippocampus and thalamus. Then he mainly focused on thalamus and spinal cord to pursue the MRI biomarkers to monitor the clinical disability and disease progression. He utilized Yaou LIU these MRI biomarkers to achieve early diagnosis, assess therapeutic effect and predict clinical conversion. These findings offered theoretical principles and clinical biomarkers for cognitive impairment and clinical disability of NMOSD, with

scientific and clinical significance, and can be extended and applied to other neurological diseases.

Yaou was awarded two PhD from Capital Medical University (, 2013) and VU University, Amsterdam (The Netherlands,2017) , he has published 55 SCI papers including Immunity, Brain, Neurology, Radiology, which have been cited 747 times. He is the chief editor of the book “Neuroimage in central nervous system demyelinating diseases”(in Chinese). Fifteen international prizes in neuroimage and neuroimmune disease field were awarded including McDonald Fellowship from Multiple Sclerosis International Federation (MSIF), Young investigator award and Best poster award of Pan-Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Educational award from American society of MS (ACTRIMS), Merit Award from Radiological Society of North America (RSNA). He serves as the committee member for several international scientific organizations e.g. Central Organizing and Scientific Committee of PACTRIMS, Editor of Neuroradiology and principle investigator of three national funds.

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Urs is an Associate Professor at the Department of Psychology at the Chinese University of Hong Kong.

His research focuses on cognitive and neural aspects of spoken and written language processing. He is particularly interested in reading acquisition, dyslexia, and second language learning. One goal of his work is to use neural markers of language processing to inform screening and intervention practices for dyslexia. His research involves behavioral and functional neuroimaging techniques, such as EEG and fMRI.

He received his PhD at the University of Zurich, Switzerland. He then pursued postdoctoral studies at the University of Zurich and at the Weill Urs MAURER Medical College of Cornell University in . Before joining the Chinese University of Hong Kong he was an Assistant Professor at the University of Zurich, funded through the Swiss National Science Foundation’s prestigious research professor scheme.

Lin is an Associate Professor in Department of Imaging and Interventional Radiology (DIIR), The Chinese University of Hong Kong. She is the Director of Division of Imaging Informatics, DIIR. Her research interests are mainly in the field of multimodal image quantification of brain to support clinical research and practice. She has been awarded the Best Young Engineer’s Paper Award, by Biomedical Division, The Hong Kong Institution of Engineers. She founded a startup company, BrainNow Ltd. to promote the clinical applications of neuroimage analysis technology, which won the Gold Award with the Congratulations of the Jury in the 46th International Lin SHI Exhibition of Inventions Geneva in 2018.

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Yannie is a Neurologist, Clinical Professional Consultant and Honorary Clinical Assistant Professor at CUHK. After graduating from CUHK in year 2000, she underwent neurology training at Prince of Wales Hospital, and overseas training in stroke neuroimaging in Massachusetts General Hospital, Boston. In 2012, she pioneered 24-hour thrombolysis using telestroke with iPad in Hong Kong, which won the Asia Pacific HIMSS Healthcare award in 2013 and the Hospital Authority Outstanding Team award in Hong Kong in 2019. She is one of the founders of the CU Stroke Angels, and is currently leading the Pre-hospital Stroke Notification Yannie SOO Programme at Prince of Wales Hospital. Her major research interests include safety of anti-thrombotic therapy in patients with cerebral microbleeds, cardioembolic stroke, stroke rehabilitation with robotic devices and intracranial stenosis.

Yannie is the Principal Investigator of a number of local and international clinical trials, (e.g. IPAAC, i-SAVE, THALES, ESUS, ETNA- AF studies etc) and Steering Committee of the Microbleeds International Collaborative Network. She is also leading a number of research projects supported by local and international competitive grants, including HMRF and EMRISTA etc.

Raymond is a Biomedical Engineer and he is currently a Professor and Chairman in the Department of Biomedical Engineering, CUHK. His research interests include Rehabilitation Robotics (e.g. Hand of Hope), Brain-Computer Control Interface (BCI), Neural Engineering, Functional Electrical Stimulation(FES) and Cognitive Assessment Software. Prof. Tong is recognized for his accomplishment in innovation and applied scientific research in neuro-rehabilitation for stroke patients and the elderly. Over the years, he has made great strides in developing a wide range of rehabilitation devices. His innovative work on rehabilitation robot system “Hand of Hope” was

Raymond TONG the first Hong Kong invention to have received the grand prize in the 40-year history of the International Exhibition of Inventions of Geneva.

Recently, Raymond using advanced 3D printing technology to

develop a new generation of robotic hand for stroke rehabilitation.

The personalized soft robot hand is light and comfort for more hand

function training. His research, innovation and service have received Awardee of the 2013 Hong Kong Ten Outstanding Young Persons; Winner Award(e-Health) in the Asia Pacific ICT Award 2012; and HKIE innovation awards for young members(2008), gold awards in international invention exhibitions (04’, 07’,10’,15’ &16’). Webpage: http://www.bme.cuhk.edu.hk/kytong

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Patrick holds the Stanley Ho Chair in Cognitive Neuroscience, is Professor of Linguistics and Professor of Otolaryngology (by courtesy), and serves as the Founding Director of the Brain and Mind Institute at The Chinese University of Hong Kong. Prior to joining CUHK in 2013, he was a tenured faculty at Northwestern University where he had begun his faculty career a decade before. After undergraduate and graduate training in linguistics and cognitive psychology at the University of Texas at Austin, Patrick completed a postdoctoral fellowship in neuroscience at the University of Chicago Medical School in 2003. During the same period, he also received clinical training in speech-language pathology and is licensed to practice in the State of Illinois. He is admitted to full (registered/certified) membership of the Hong Kong Institute of Speech Therapists and the American Speech- Patrick WONG Language-Hearing Association. A versatile and effective teacher, research mentor, and clinical educator, Patrick is a two-time recipient of the Faculty Outstanding Teaching Award at CUHK.

As a cognitive neuroscientist, linguist, and speech-language pathologist, Patrick’s research covers a wide range of basic and translational issues concerning the neural basis and disorders of language and music. His work on language learning attempts to explain the sources of individual differences by focusing on the neural and neurogenetic markers of learning. His work on the association between language and music provides evidence for the neurophysiological mechanisms behind such an association at the auditory brainstem. In what is now considered

traditional phonetics, Patrick s research addresses phonetic constancy and representation, as well as phonetic learning. For over a decade, his research team has been funded continuously by the National Institutes of Health in the US, with current funding from both US and Hong Kong sources. He has also served on funding agency review panels in Hong Kong and the US, including the Research Grants Council (RGC) (Hong Kong), the NIH, and the US Department of Veteran Affairs. His research has appeared in a broad array of interdisciplinary scholarly venues covering both neuroscience and language works including journals such as Nature Neuroscience, Proceedings of the National Academy of Sciences of the USA, Journal of Neuroscience, Neuroscience & Biobehavioral Reviews, and Journal of Speech, Language, and Hearing Research. He was awarded the Independent Scientist Award and the Humanities and Social Sciences Prestigious Fellowship by the NIH and RGC, respectively. Patrick’s research has also received public attention from media outlets such as The New York Times and The Wall Street Journal, and the British Broadcasting Corporation/Public Radio International.

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Savio is an Associate Professor at the Department of Educational Psychology and the director of the Laboratory for Brain and Education (LABBE) at CUHK. Savio received his Bachelor in Cognitive Science and Ph.D. in Psychology from the University of Hong Kong. Before joining CUHK in 2017, he served as a Postdoctoral Research Associate at the University of Western Ontario and the University of Southern California, the Founding Director of the Centre for Brain and Education and Associate Head of the Department of Special Education and Counselling at the Education University of Hong Kong. He received Fulbright-RGC HK Senior Research Scholar Award and was appointed as a Visiting Associate Professor at the Massachusetts Institute of Technology in 2018. Savio WONG Savio has been studying the neural mechanism and physiological correlate of impulsivity and decision-making in adolescents using fMRI and psychophysiology. Recently, Savio and his collaborators have developed a wearable sensor system which can be used to monitor the emotional responses of students with special educational needs (e.g. Autism and ADHD) in a classroom setting. Savio's projects are funded by the Research Grant Council and the Innovation and Technology Fund.

. Zsolt is a British-Hungarian Neurosurgeon completing his fellowship training at the University of Toronto. He has a passion to create translational bridges between neuroscience and applied machine learning. His areas of research include untangling the heterogeneity of diseases using advanced data analytics.

He earned his medical degree and PhD from the University of Szeged, Hungary and completed his postdoctoral fellowship at the University of California San Francisco, Department of Neurosurgery.

Zsolt ZADOR For his neurosurgical training he moved to Manchester, where he was awarded an NIHR Academic Lectureship and was granted an NHS Entrepreneur award. He is a fellow of the Royal College of Surgeons of England. Whilst in Manchester he became devoted to coding, machine learning and started formal training in health data sciences. He subsequently completed a cranial base fellowship at the University of Toronto and currently holds the Michael and Amira Dan Fellowship in Neurosurgery.

His most recent publications appeared in Critical Care, AMIA and Journal of Neurosurgery, studies that use machine learning tools to improve diagnostics and treatments for biologically heterogenous diseases.