Learning from Lister
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Epidemic Models
Chapter 9 Epidemic Models 9.1 Introduction to Epidemic Models Communicable diseases such as measles, influenza, and tuberculosis are a fact of life. We will be concerned with both epidemics, which are sudden outbreaks of a disease, and endemic situations, in which a disease is always present. The AIDS epidemic, the recent SARS epidemic, recurring influenza pandemics, and outbursts of diseases such as the Ebola virus are events of concern and interest to many peo- ple. The prevalence and effects of many diseases in less-developed countries are probably not as well known but may be of even more importance. Every year mil- lions, of people die of measles, respiratory infections, diarrhea, and other diseases that are easily treated and not considered dangerous in the Western world. Diseases such as malaria, typhus, cholera, schistosomiasis, and sleeping sickness are endemic in many parts of the world. The effects of high disease mortality on mean life span and of disease debilitation and mortality on the economy in afflicted countries are considerable. We give a brief introduction to the modeling of epidemics; more thorough de- scriptions may be found in such references as [Anderson & May (1991), Diekmann & Heesterbeek (2000)]. This chapter will describe models for epidemics, and the next chapter will deal with models for endemic situations, but we begin with some general ideas about disease transmission. The idea of invisible living creatures as agents of disease goes back at least to the writings of Aristotle (384 BC–322 BC). It developed as a theory in the sixteenth century. The existence of microorganisms was demonstrated by van Leeuwenhoek (1632–1723) with the aid of the first microscopes. -
Medicine in 18Th and 19Th Century Britain, 1700-1900
Medicine in 18th and 19th century Britain, 1700‐1900 The breakthroughs th 1798: Edward Jenner – The development of How had society changed to make medical What was behind the 19 C breakthroughs? Changing ideas of causes breakthroughs possible? vaccinations Jenner trained by leading surgeon who taught The first major breakthrough came with Louis Pasteur’s germ theory which he published in 1861. His later students to observe carefully and carry out own Proved vaccination prevented people catching smallpox, experiments proved that bacteria (also known as microbes or germs) cause diseases. However, this did not put an end The changes described in the Renaissance were experiments instead of relying on knowledge in one of the great killer diseases. Based on observation and to all earlier ideas. Belief that bad air was to blame continued, which is not surprising given the conditions in many the result of rapid changes in society, but they did books – Jenner followed these methods. scientific experiment. However, did not understand what industrial towns. In addition, Pasteur’s theory was a very general one until scientists begun to identify the individual also build on changes and ideas from earlier caused smallpox all how vaccination worked. At first dad bacteria which cause particular diseases. So, while this was one of the two most important breakthroughs in ideas centuries. The flushing toilet important late 19th C invention wants opposition to making vaccination compulsory by law about what causes disease and illness it did not revolutionise medicine immediately. Scientists and doctors where the 1500s Renaissance – flushing system sent waste instantly down into – overtime saved many people’s lives and wiped‐out first to be convinced of this theory, but it took time for most people to understand it. -
Medicine in Eighteenth and Nineteenth Century Britain, C.1700-C.1900
Year 10 History Knowledge Organiser – Key topic 3: Medicine in eighteenth and nineteenth century Britain, c.1700-c.1900 2. Key dates 1. Key terms 1 1796 Edward Jenner tested his vaccine on James Phipps. He infected him with cowpox, and this 1 Microbes A living organism which is too small to see prevented him catching smallpox. without a microscope, this includes 2 1842 Edwin Chadwick published his ‘Report on the Sanitary Conditions of the Labouring Classes’. bacteria. 1847 James Simpson discovered that chloroform could be used as an anaesthetic. 2 The A movement of European intellectuals that 3 Enlightenment emphasised reason rather than tradition. 4 1848 First Public Health Act – set up Boards of Health but was not compulsory. 3 Decaying Matter Material, such as vegetables or animals, that has died and is rotting. 5 1854 John Snow mapped the spread of disease around the Broad Street pump to prove that cholera was caused by dirty water. 4 Bacteriology The study of bacteria. 6 1858 The Great Stink near the Houses of Parliament prompted action on sewage. 5 Tuberculosis A disease which affects the lungs causing serious difficulties in breathing. 7 1861 Louis Pasteur published the Germ Theory 6 Cholera A waterborne disease which killed many 1865 Joseph Lister used carbolic acid for the first time. He wrapped up a leg after an operation in th 8 people in the 19 century by causing the acid-soaked bandages and the wound healed cleanly. body to become dehydrated. 9 1875 Second Public Health Act, made government intervention in public health compulsory. -
Information Issued by The
Volume XXIII No. 4 April, 1968 INFORMATION ISSUED BY THE ASSOCIATION OF JEWISH REFUGEES IN GREAT BRITAIN fiobert Wehsch Elly Heuss were present. They were waiting for an attack on Stolper's house that evening which, however, did not occur then (it took place three nights later). All were very pessi DATES TO REMEMBER mistic but did not know what to do. Miss Wiskemann was not in Berlin on the When the first great blow fell on German Jews a strong sense of destiny and of soli 1st of April and she does not mention that Jewry just 35 years ago, only very few people darity, but they also made possible an orderly spectacular date at all. She went back to realised that this was an event of universal emigration of a large part of the Jewish London on March 26 and was deeply dis importance which opened the floodgate to population. appointed when she noticed the apathy and destruction and chaos in the whole of Europe, This was by no means an easy job. It is incredulity of the public. Even such men ^^i indeed in the whole world. unnecessary to point out that emigration from as Sir Herbert Samuel and Colonel Wedgwood The 1st of April, 1933, remains inscribed a country where one had thought to be secure are said to have been unresponsive to her 5s a black day in the Jewish Calendar. Those is a shattering event, not only economically warnings. In London, she felt, " it was quite Who remember it know well that on that day and socially but also psychologically. -
History of Biostatistics
History of biostatistics J. Rosser Matthews University of Maryland, College Park, MD, USA Correspondence to: J. Rosser Matthews Professional Writing Program English Department 1220 Tawes Hall University of Maryland College Park, MD, USA +1 (301) 405-3762 [email protected] Abstract The history of biostatistics could be viewed as an ongoing dialectic between continuity and change. Although statistical methods are used in current clinical studies, there is still ambivalence towards its application when medical practitioners treat individual patients. This article illustrates this dialectic by highlighting selected historical episodes and methodological innovations – such as debates about inoculation and blood - letting, as well as how randomisation was introduced into clinical trial design. These historical episodes are a catalyst to consider assistance of non-practitioners of medicine such as statisticians and medical writers. Methodologically, clinical trials and dialectic by discussing examples from different types of diseases.1 While basically epidemiological studies are united by a antiquity to the emergence of the clinical qualitative, the work is historically population-based focus; they privilege the trial in the mid-20th century. significant because it looked beyond the group (i.e., population) over the clinically individual to suggest a role for larger unique individual. Over time, this pop - Ancient sources: Hippocratic geographic and environmental factors. ulation-based thinking has remained writings and the bible Furthermore, it relied on naturalistic constant; however, the specific statistical Although the Hippocrates writers (active in explanations rather than invoking various techniques to measure and assess group the 5th century BCE) did not employ deities to account for illness and therefore characteristics have evolved. -
Joseph Lister
JOSEPH LISTER By W. W. CH~PMAN, MONTREAL O-NIGHT is the fourteenth Convocation of our College, and Sir Ewen Maclean and myself are to say something to you. My own share of the honour and the Tobligation is to take the form of a Presidential Address, and you will agree that this is a serious undertaking. May I profess at once that I have been animated and encouraged to this task by the words of my predecessor in office, Rudolph Matas, of New Orleans. The admirable address of last year on "The Miasions and Ideals of the American College of Surgeons," has been to me, as to you all, a genuine help and inspiration; his well-timed message represents for the College, not only a prophecy but a fulfillment. A college of surgeons, if it means anything, is really a post-graduate school, a school in which we are enrolled during our. working life. As Fellows of this school, we enjoy many advantages, but we also incur a large responsibility. It is true that there is no definite academic staff, but what is much better, we teach one another; teach both by precept and example, the science and the art of surgery. And our curriculum comprises much more than this. We provide a common tribunal be- fore which new methods of surgical practice may be adjudged; we promote and encourage research; and we are earnestly concerned with the character and repu- tation of our Fellows. In a word, by attendance at this school, we are stimulated and encouraged to greater usefulness, more completely to find ourselves. -
Infection Control Through the Ages
American Journal of Infection Control 40 (2012) 35-42 Contents lists available at ScienceDirect American Journal of Infection Control American Journal of Infection Control journal homepage: www.ajicjournal.org Major article Infection control through the ages Philip W. Smith MD a,*, Kristin Watkins MBA b, Angela Hewlett MD a a Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE b Center for Preparedness Education, College of Public Health, University of Nebraska Medical Center, Omaha, NE Key Words: To appreciate the current advances in the field of health care epidemiology, it is important to understand History the history of hospital infection control. Available historical sources were reviewed for 4 different Hospitals historical time periods: medieval, early modern, progressive, and posteWorld War II. Hospital settings Nosocomial for the time periods are described, with particular emphasis on the conditions related to hospital infections. Copyright Ó 2012 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Approximately 1.7 million health careeassociated infections One of the few public health measures was the collection of (HAIs) occur in the United States each year.1 Hospital infection bodies of plague victims. The bodies were left in the street to be control programs are nearly universal in developed nations and have picked up by carts and placed in mass graves outside of town.3,4 significantly lowered the risk of acquiring a HAI since their inception Other infection control measures included hanging people who in the mid 20th century. As we debate the preventability of HAIs, as wandered in from an epidemic region into an uninfected area, well as the ethical and logistic aspects of patient safety, it is impor- shutting up plague victims in their homes, and burning clothing tant to recall the historical context of hospital infection control. -
Medicine Through Time
RENAISSANCE MODERN MEDICINE Antibiotics Harvey Vesalius Pare Chemotherapy Blood anatomy Ligature Circulation detailed illustrations War surgeon Diabetes DNA Veins student observation cauterisation Arteries grave robbing battlefields Gene therapy Genetics Dissection challenged Galen wound MEDICINE THROUGH Experiments septum printing press Heart transplant Observations human jaw re-birth Influenza Heart Fabric of the Human body questioning Magic bullet TIME blood re-circulated Microscope experimentation Key hole surgery heart similar to pump Penicillin Radiotherapy GREEK AND ROMAN TIMES Jenner inoculation NHS Four Humours army supernatural Smallpox opposition Bevan Galen balanced/unbalanced natural Cowpox Stem cell research Hippocrates Asclepius gymnasium Milk lady X Ray Hippocratic oath dissection hygiene Vaccine Test tube baby Observation and Recording herbs theory of the Government MRSA Diet votive opposites Observation Exercise temple sewer Aqueduct bath latrine Drain slaves sauna MEDIEVAL MEDICINE INDUSTRIAL MEDICINE SURGERY Four humours Cholera Bazelgette Blood Purging The great stink sewers Anaesthetics Theory of the opposites Germs Chadwick Antiseptics Bloodletting Bacteria report Blood transfusions Quacks Government recommendations Hygiene Barber surgeons Laissez faire acts Scrubs Leeches Factories tax Sterilisation Plague Overcrowding local councils Operating theatre Black death Pollution Medical officers Inhalation Superstitious Cess pits Bacteria Religion Toilets Carbolic acid punishment Water pumps Infection The church Death rates Pain Disease Miasma Blood loss Galen & Hippocrates Poor living conditions Ether Hotel De Dieu Sewerage Laughing gas Almshouses Slums Chloroform Leper houses Epidemic Joseph Lister Monasteries Typhoid James Simpson Hospitals Tuberculous Nuns Rubbish Urine chart population Herbal remedies Prayer miasma . -
Gibraltar's 1804 Yellow Fever Scourge: the Search for Scapegoats
See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/51307253 Gibraltar's 1804 Yellow Fever Scourge: The Search for Scapegoats Article in Journal of the History of Medicine and Allied Sciences · January 1998 DOI: 10.1093/jhmas/53.1.3 · Source: PubMed CITATIONS READS 7 354 2 authors: Larry Sawchuk Stacie Burke University of Toronto University of Manitoba 32 PUBLICATIONS 138 17 PUBLICATIONS 61 CITATIONS CITATIONS SEE PROFILE SEE PROFILE Some of the authors of this publication are also working on these related projects: influenza 1918 View project All content following this page was uploaded by Larry Sawchuk on 22 January 2016. The user has requested enhancement of the downloaded file. Gibraltar's 1804 Yellow Fever Scourge: The Search for Scapegoats LAWRENCE A. SAWCHUK and STACIE D. A. BURKE Mrs Baynes was obliged to put both Mr Frome [the garrison chaplain] and his wife in their coffins, not having any creature near her, nor could she get them buried till the Governor ordered some men who were then in the street to be pressed for that purpose. How the town is to be cleansed we can scarcely tell, we fear dead bodies are at this moment shut up ... our men at the sick lines need to be for ever running to the main guard to beg them to remove the dead from our street, there being six persons lying there, and there was no other chance of getting their dead buried but by doing so. Miss Fletcher, who is now a very pretty young woman, was seen . -
Provision and Access to Healthcare in a Historical Perspective
HYGIEA INTERNATIONALIS An Interdisciplinary Journal for the History of Public Health Volume 5, No. 1, 2006 Special Issue Provision and access to healthcare in a historical perspective Editors Martin Dinges, Jan Sundin and Sam Willner ISSN, Print: 1403-8668; Electronic: 1404-4013 URL: http://www.ep.liu.se/ej/hygiea/ Editorial Board Giovanni Berlinguer, University of Rome “La Sapienza”, Italy Virginia Berridge, London School of Hygiene and Tropical Medicine, U.K. Patrice Bourdelais, École des Hautes Études en Sciences Sociales, France Linda Bryder, University of Auckland, New Zealand Marcos Cueto, Instituto de Estudios Peruanos, Peru Christopher Hamlin, University of Notre Dame, U.S.A. Robert Jütte, Robert Bosch Stiftung, Germany Øivind Larsen, University of Oslo, Norway Marie C. Nelson, Linköping University, Sweden Dorothy E. Porter, University of California, U.S.A. Günter B. Risse, University of California, U.S.A. Esteban Rodriguez-Ocaña, University of Granada, Spain John Rogers, Uppsala University, Sweden Jan Sundin, Linköping University, Sweden Lars-Göran Tedebrand, Umeå University, Sweden John H. Woodward, The University of Sheffield, U.K. Editorial Committee Laurinda Abreu, Patrice Bourdelais, Peter Berkesand, Jan Sundin and Sam Willner Copyright This journal is published under the auspices of Linköping University Electronic Press. All Authors retain the copyright of their articles. © Linköping University Electronic Press and the Authors Table of Contents Volume 5, No. 1, 2006 Editorial Sam Willner Preface 5 Martin Dinges Introduction -
EJC Cover Page
Early Journal Content on JSTOR, Free to Anyone in the World This article is one of nearly 500,000 scholarly works digitized and made freely available to everyone in the world by JSTOR. Known as the Early Journal Content, this set of works include research articles, news, letters, and other writings published in more than 200 of the oldest leading academic journals. The works date from the mid-seventeenth to the early twentieth centuries. We encourage people to read and share the Early Journal Content openly and to tell others that this resource exists. People may post this content online or redistribute in any way for non-commercial purposes. Read more about Early Journal Content at http://about.jstor.org/participate-jstor/individuals/early- journal-content. JSTOR is a digital library of academic journals, books, and primary source objects. JSTOR helps people discover, use, and build upon a wide range of content through a powerful research and teaching platform, and preserves this content for future generations. JSTOR is part of ITHAKA, a not-for-profit organization that also includes Ithaka S+R and Portico. For more information about JSTOR, please contact [email protected]. [ 441 ] PRESENTSP R E S E N- T S RECEIVED BY THE ROYAL SOCIETY, From November 1820 to July 1821. WITH THE NAMES OF THE DONORS. 1.820, PRESENTS. DONORS. Nov. 9. Karamania, or a brief Description of the South Capt. Francis Beaufort. Coast of Asia Minor, and of the Remains of An- tiquity, with Plans, Views, &c. Collected du- ring a Survey of that Coast under the orders of the Lords Commissioners of the Admiralty, in 1811 and 1812, by Francis Beaufort, Esq. -
Final Copy 2018 11 06 Zarok
This electronic thesis or dissertation has been downloaded from Explore Bristol Research, http://research-information.bristol.ac.uk Author: Zarokostas, Evangelos Title: From observatory to dominion geopolitics, colonial knowledge and the origins of the British Protectorate of the Ionian Islands, 1797-1822 General rights Access to the thesis is subject to the Creative Commons Attribution - NonCommercial-No Derivatives 4.0 International Public License. A copy of this may be found at https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode This license sets out your rights and the restrictions that apply to your access to the thesis so it is important you read this before proceeding. Take down policy Some pages of this thesis may have been removed for copyright restrictions prior to having it been deposited in Explore Bristol Research. However, if you have discovered material within the thesis that you consider to be unlawful e.g. breaches of copyright (either yours or that of a third party) or any other law, including but not limited to those relating to patent, trademark, confidentiality, data protection, obscenity, defamation, libel, then please contact [email protected] and include the following information in your message: •Your contact details •Bibliographic details for the item, including a URL •An outline nature of the complaint Your claim will be investigated and, where appropriate, the item in question will be removed from public view as soon as possible. From observatory to dominion: geopolitics, colonial knowledge and the origins of the British Protectorate of the Ionian Islands, 1797-1822 Evangelos (Aggelis) Zarokostas A dissertation submitted to the University of Bristol in accordance with the requirements for award of the degree of PhD, Historical Studies in the Faculty of the Arts, School of Humanities, June 2018 word count: 73,927 1 Abstract The thesis explores official information-gathering and colonial rule during the transition which led to the British Protectorate of the Ionian Islands, between 1797 and 1822.