O0041 Catch-up vaccination practices of French physicians for migrants arriving in France Vignier Nicolas*1,2,3,2, Sohela Moussaoui2, Louise Luan1, Anne Marie Aurousseau4,5, Sylvain Nappez6, Julian Cornaglia7, Gaylord Delobre8, Sophie Blanchi9, Olivier Bouchaud10, Odile Launay11, Matthieu Méchain12

1 Groupe hospitalier Sud Ile-de-France, Melun, France, 2 Institut Pierre Louis d’Epidé miologie et de Santé Publique (IPLESP, Inserm, Sorbonne Université, UMRS 1136), Department of Social Epidemiology, Paris, France, 3 Société de Pathologie Infectieuse de Langue Française, Groupe Vaccination Prévention, Paris, France, 4 Université de Bordeaux, 5 France, 6 Amiens University Hospital, France, 7 Perpignan Hospital, Perpignan, 8 Réseau Louis Guilloux, Rennes, France, 9 Hospital Center - Le Mans, Le Mans, France, 10 Avicenne Hospital (AP-HP), Bobigny, France, 11 Hospital Cochin, Paris, France, 12 Hospital Saint-André - Hospital Group Saint-André Chu De Bordeaux, Bordeaux, France Background: Migrants often underwent an incomplete vaccination scheme regarding the French recommendations. The aim of this study is to evaluate the practices of French doctors in terms of catch-up vaccination. Materials/methods: A study of French physicians’ practices about infectious diseases prevention among migrants was conducted in 2016-2018 using an auto-administered questionnaire. Physicians were asked to participate via email widely broadcast, in partnership with several scientific societies representing several specialties (general practitioners, paediatricians, infectious diseases, etc.) Results: In total, 371 practitioners answered the survey. The respondents were 42 years old in median, 65% were female, 43% worked in Paris region, 37% in infectious and tropical diseases units and/or in free and anonymous screening centres. They were questioned on the modalities of the catch-up vaccination in case of management of a 35 years old migrant from Africa having an unknown vaccination status: 33% of them perform a complete immunisation catch up 26% consider that the childhood immunisations have been done, and continue the immunisation schedule (more often for general practitioners 31% vs 27%, p<0.05) 23% use a specialised website to learn more about the country of origin vaccination schedule 33% use pre-vaccination serologies (mainly hepatitis B) 17% use post-vaccination serologies (mainly tetanus, more often physicians in infectious diseases units and/or vaccination centres or screening centres, p<0.001) When a migrant declares to be up-to-date with his immunisations, only 53% of doctors consider this information reliable. Majority of respondents do not perform more than 2 injections on the same day. Regarding serologies, when we take the example of the catch-up immunisation of a 4 years-old Eritrean child, 67% use a pre-vaccination hepatitis B serology, 53% use a HIV serology, 53% do a tuberculin skin test or a IGRA test, 38% a measles serology, 20% a tetanus pre-vaccination serology, 20% a tetanus post-vaccination serology, and 12% make no blood sample. Conclusions: Practices among French doctors regarding the catch-up immunisation is heterogeneous. The redaction of practical recommendations on the basis of available data, and taking into account the difficulties in implementation is necessary to enhance the vaccination of this population.

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