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Hypertension by Classification 10/22/02 5:21 PM

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HYPERTENSION MEDICATIONS BY CLASSIFICATION

ADRENERGIC NEURON ANTAGONISTS (PERIPHERALLY ACTING)

HYLOREL () ISMELIN () SERPALAN () SERPASIL (reserpine)

COMBINATIONS: ( + ) DIUPRES (reserpine + ) DIUTENSEN-R (reserpine + ) ENDURONYL ( + methyclothiazide) ESIMIL (guanethidine + ) HYDROPRES (reserpine + hydrochlorothiazide) HYDRO-SERP (reserpine + hydrochlorothiazide) HYDROSERPINE (reserpine + hydrochlorothiazide) METATENSIN (reserpine + ) RAUZIDE (rauwolfia serpentina + ) RENESE-R (reserpine + ) SALUTENSIN (reserpine + )

COMBINATIONS: (adrenergic antagonist + vasodilator + thiazide diuretic) HYDRAP-ES (reserpine + hydralazine + hydrochlorothiazide) MARPRES (reserpine + hydralazine + hydrochlorothiazide) SER-AP-ES (reserpine + hydralazine + hydrochlorothiazide) TRI-HYDROSERPINE (reserpine + hydralazine + hydrochlorothiazide)

COMBINATIONS: (adrenergic antagonist + monosulfamyl diuretic) DEMI-REGROTON (reserpine + chlorthalidone) REGROTON (reserpine + chlorthalidone)

ALPHA ADRENERGIC AGONISTS (CENTRALLY ACTING) http://www.hypertensionmeds.com/bpmed3.html Page 1 of 7 Hypertension Medications by Classification 10/22/02 5:21 PM

ALDOMET () AMODOPA (methyldopa) CATAPRES () CATAPRES-TTS(clonidine) TENEX () WYTENSIN ()

COMBINATIONS: (alpha agonist + thiazide diuretic) ALDOCLOR (methyldopa + chlorothiazide) ALDORIL (methyldopa + hydrochlorothiazide)

COMBINATIONS: (alpha agonist + monosulfamyl diuretic) CLORPRES (clonidine + chlorthalidone) COMBIPRES (clonidine + chlorthalidone)

ALPHA ADRENERGIC BLOCKERS

CARDURA () HYTRIN (terazosin) MINIPRESS ()

COMBINATIONS: (alpha adrenergic blocker + thiazide diuretic) MINIZIDE (prazosin + polythiazide)

ALPHA & BETA BLOCKERS

COREG (carvedilol) NORMODYNE (labetalol) TRANDATE (labetalol)

ANGIOTENSIN II RECEPTOR BLOCKERS

ATACAND (candesartan cilexetil) AVAPRO (irbesartan) BENICAR (olmesartan medoxomil) COZAAR (losartan) DIOVAN (valsartan) MICARDIS (telmisartan) TEVETEN (eprosartan)

COMBINATIONS: (angiotensin II receptor blocker + thiazide diuretic) ATACAND HCT (candesartan cilexetil + hydrochlorothiazide) AVALIDE ( irbesartan + hydrochlorothiazide)

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DIOVAN HCT (valsartan + hydrochlorothiazide) HYZAAR (losartan + hydrochlorothiazide) MICARDIS HCT (telmisartan + hydrochlorothiazide)

ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS

ACCUPRIL (quinapril) ACEON (perindopril) ALTACE (ramipril) CAPOTEN (captopril) LOTENSIN (benazepril) MAVIK (trandolapril) MONOPRIL (fosinopril) PRINIVIL (lisinopril) UNIVASC (moexipril) VASOTEC (enalapril) ZESTRIL (lisinopril)

COMBINATIONS: (ace inhibitor + thiazide diuretic) ACCURETIC (quinapril + hydrochlorothiazide CAPOZIDE (captopril + hydrochlorothiazide) LOTENSIN HCT (benazepril + hydrochlorothiazide) PRINIZIDE (lisinopril + hydrochlorothiazide) UNIRETIC (moexipril + hydrochlorothiazide) VASERETIC (enalapril + hydrochlorothiazide) ZESTORETIC (lisinopril + hydrochlorothiazide)

COMBINATIONS: (ace inhibitor + calcium channel blocker) LEXXEL (enalapril + felodipine) LOTREL (benazepril + amlodipine) TARKA (trandolapril + verapamil) TECZEM (Discontinued) (enalapril + diltiazem)

BETA ADRENERGIC BLOCKERS

BETACHRON E-R (propranolol) BLOCADREN (timolol) CORGARD () INDERAL (propranolol) KERLONE (betaxolol) LOPRESSOR (metoprolol) TENORMIN (atenolol) TOPROL XL (metoprolol) ZEBETA (bisoprolol)

BETA ADRENERGIC BLOCKERS WITH INSTRINSIC SYMPATHOMIMETIC ACTIVITY (ISA) CARTROL (carteolol)

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LEVATOL () SECTRAL (acebutolol) VISKEN (pindolol)

COMBINATIONS: (beta adrenergic blocker + thiazide diuretic) CORZIDE (nadolol + bendroflumethiazide) INDERIDE (propranolol + hydrochlorothiazide) LOPRESSOR HCT (metoprolol + hydrochlorothiazide) TIMOLIDE (timolol + hydrochlorothiazide) ZIAC (bisoprolol + hydrochlorothiazide)

COMBINATIONS: (beta adrenergic blocker + monosulfamyl diuretic) TENORETIC (atenolol + chlorthalidone)

CALCIUM CHANNEL BLOCKERS

DIHYDROPYRIDINES ADALAT CC (nifedipine) CARDENE SR (nicardipine) CARDENE (nicardipine) DYNACIRC CR (isradipine) DYNACIRC (isradipine) NORVASC (amlodipine) PLENDIL (felodipine) PROCARDIA XL (nifedipine) PROCARDIA (nifedipine) SULAR (nisoldipine)

PHENYLAKYLAMINES CALAN SR (verapamil) CALAN (verapamil) COVERA HS (verapamil) ISOPTIN SR (verapamil) ISOPTIN (verapamil) VERELAN PM (verapamil) VERELAN (verapamil)

BENZOTHIAZEPINES CARDIZEM CD (diltiazem) CARDIZEM SR (diltiazem) CARDIZEM (diltiazem) DILACOR XR (diltiazem) TIAZAC (diltiazem)

TETRALOL POSICOR (mibefradil) WITHDRAWN FROM THE MARKET

COMBINATIONS: (calcium channel blocker + ace inhibitor) LEXXEL (felodipine + enalapril)

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LOTREL (amlodipine + benazepril) TARKA (verapamil + trandolapril) TECZEM (Discontinued) (diltiazem + enalapril)

THIAZIDES & RELATED

THIAZIDE DIURETICS ANHYDRON () AQUATENSEN (methyclothiazide) DIUCARDIN (hydroflumethiazide) DIURESE (trichlormethiazide) DIURIGEN (chlorothiazide) DIURIL (chlorothiazide) ENDURON (methyclothiazide) ESIDRIX (hydrochlorothiazide) EXNA (benzthiazide) EZIDE (hydrochlorothiazide) HYDREX (benzthiazide) HYDRODIURIL (hydrochlorothiazide) HYDRO-PAR (hydrochlorothiazide) METAHYDRIN (trichlormethiazide) MICROZIDE (hydrochlorothiazide) NAQUA (trichlormethiazide) NATURETIN (bendroflumethiazide) ORETIC (hydrochlorothiazide) RENESE (polythiazide) SALURON (hydroflumethiazide)

SULFONAMIDE DIURETICS HYGROTON (chlorthalidone) LOZOL () THALITONE (chlorthalidone)

QUINAZOLINE DIURETICS DIULO () {extended form which is interchangeable with zaroxolyn} HYDROMOX () MYKROX (metolazone) {prompt form which is not interchangeable with zaroxolyn} ZAROXOLYN (metolazone) {extended form which is not interchangeable with mykrox}

LOOP DIURETICS BUMEX () DEMADEX (torsemide) EDECRIN (ethacrynic acid) LASIX ()

POTASSIUM SPARING DIURETICS ALDACTONE () DYRENIUM () MIDAMOR ()

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COMBINATIONS: (potassium sparing diuretic + thiazide diuretic) ALDACTAZIDE (spironolactone + hydrochlorothiazide) DYAZIDE (triamterene + hydrochlorothiazide) MAXZIDE (triamterene + hydrochlorothiazide) MODURETIC (amiloride + hydrochlorothiazide)

COMBINATIONS: (thiazide diuretic + ace inhibitor) ACCURETIC (hydrochlorothiazide + quinapril) CAPOZIDE (hydrochlorothiazide + captopril) LOTENSIN HCT (hydrochlorothiazide + benazepril) PRINIZIDE (hydrochlorothiazide + lisinopril) UNIRETIC (hydrochlorothiazide + moexipril) VASERETIC (hydrochlorothiazide + enalapril) ZESTORETIC (hydrochlorothiazide + lisinopril)

COMBINATIONS: (thiazide diuretic + angiotensin II receptor blocker) ATACAND HCT (candesartan cilexetil + hydrochlorothiazide) AVALIDE (hydrochlorothiazide + irbesartan) DIOVAN HCT (hydrochlorothiazide + valsartan) HYZAAR (hydrochlorothiazide + losartan) MICARDIS HCT (hydrochlorothiazide + telmisartan)

COMBINATIONS: (thiazide diuretic + adrenergic antagonist) DIUPRES (chlorothiazide + reserpine) DIUTENSEN-R (methyclothiazide + reserpine) HYDROPRES (hydrochlorothiazide + reserpine) HYDRO-SERP (hydrochlorothiazide + reserpine HYDROSERPINE (hydrochlorothiazide + reserpine) METATENSIN (trichlormethiazide + reserpine) RAUZIDE (bendroflumethiazide + rauwolfia serpentina) RENESE-R (polythiazide + reserpine) SALUTENSIN (hydroflumethiazide + reserpine)

COMBINATIONS: (thiazide diuretic + adrenergic antagonist + vasodilator) HYDRAP-ES (hydrochlorothiazide + reserpine + hydralazine) MARPRES (hydrochlorothiazide + reserpine + hydralazine) SER-AP-ES (hydrochlorothiazide + reserpine + hydralazine) TRI-HYDROSERPINE (hydrochlorothiazide + reserpine + hydralazine)

COMBINATIONS: (thiazide diuretic + vasodilator) APRESAZIDE (hydrochlorothiazide + hydralazine)

COMBINATIONS: (thiazide diuretic + alpha agonist) ALDORIL (hydrochlorothiazide + methyldopa) ALDOCLOR (chlorothiazide + methyldopa)

COMBINATIONS: (monosulfamyl diuretic + alpha agonist) CLORPRES (chlorthalidone + clonidine) COMBIPRES (chlorthalidone + clonidine)

COMBINATIONS: (thiazide diuretic + alpha blocker) MINIZIDE (polythiazide + prazosin) http://www.hypertensionmeds.com/bpmed3.html Page 6 of 7 Hypertension Medications by Classification 10/22/02 5:21 PM

COMBINATIONS: (thiazide diuretic + beta adrenergic blocker) CORZIDE (bendroflumethiazide + nadolol) INDERIDE (hydrochlorothiazide + propranolol) LOPRESSOR HCT (hydrochlorothiazide + metoprolol) TIMOLIDE (hydrochlorothiazide + timolol) ZIAC (hydrochlorothiazide + bisoprolol)

COMBINATIONS: (monosulfamyl diuretic + ) TENORETIC (chlorthalidone + atenolol)

COMBINATIONS: (thiazide diuretic + adrenergic antagonist) ENDURONYL (methyclothiazide + deserpidine) ESIMIL (hydrochlorothiazide + guanethidine)

VASODILATORS (DIRECT RELAXATION OF VASCULAR SMOOTH MUSCLES)

APRESOLINE (hydralazine) LONITEN (minoxidil)

COMBINATIONS: (vasodilator + thiazide diuretic) APRESAZIDE (hydralazine + hydrochlorothiazide)

COMBINATIONS: (vasodilator + adrenergic antagonist + thiazide diuretic) HYDRAP-ES (hydralazine + reserpine + hydrochlorothiazide) MARPRES (hydralazine + reserpine + hydrochlorothiazide) SER-AP-ES (hydralazine + reserpine + hydrochlorothiazide) TRI-HYDROSERPINE (hydralazine + reserpine + hydrochlorothiazide)

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